CN103127366B - Chinese materia medica preparation for treating diabetic heart disease - Google Patents

Chinese materia medica preparation for treating diabetic heart disease Download PDF

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CN103127366B
CN103127366B CN201210558720.0A CN201210558720A CN103127366B CN 103127366 B CN103127366 B CN 103127366B CN 201210558720 A CN201210558720 A CN 201210558720A CN 103127366 B CN103127366 B CN 103127366B
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heart disease
diabetic heart
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materia medica
medica preparation
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CN103127366A (en
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丰桂云
刘登富
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Abstract

The invention discloses a Chinese materia medica preparation for treating diabetic heart disease, and belongs to the field of traditional Chinese medicines. The Chinese materia medica preparation for treating the diabetic heart disease is made of the following bulk drugs, by part of weight, rhizoma anemarrhenae 9, pseudo-ginseng 12, the root of red-rooted salvia 12, mangnolia officinalis 8, paeonia suffruticosa 8, angelica sinensis 6, schisandra chinensis 9, lignum dalbergiae odoriferae 10, cape jasmine fruit 10, platycladi seed 8, radix asparagi 9, trichosanthes kirilowii maxim 9, dogwood 6, immature bitter orange 9 and herba epimedii 8. According to the Chinese materia medica preparation for treating the diabetic heart disease, natural traditional Chinese medicines are used as raw materials, curative effects are good, toxic and side effects do not exist, and a total effective rate for treating the diabetic heart disease reaches 97%.

Description

A kind of Chinese medicine preparation for the treatment of diabetic cardiopathy
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of diabetic cardiopathy, belong to the field of Chinese medicines.
Background technology
Diabetic cardiopathy is the one of the main reasons that diabetics is lethal, especially in type 2 diabetes mellitus patient.The diabetic cardiopathy of broad sense comprises coronary atherosclerotic heart disease (coronary heart disease), diabetic cardiomyopathy and diabetic heart autonomic neuropathy etc.Diabetic cardiopathy compared with ND normal onset relatively early, diabetics companion coronary heart disease often shows as painless myocardial infarction, infarct size is larger, wears wall infarction many, much more serious the state of an illness is, prognosis is poor, case fatality rate is higher.
The atherosclerotic heart disease that diabetics accelerates and myocardiac generation are except hyperglycemia, mainly also relevant with its normal merging abnormalities of sugar/lipid metabolism, mortality of hypertension increase Abnormal Blood Rheology and insulin resistant or hyperinsulinemia etc.
At present, the method of effectively not curing completely for the treatment of diabetic cardiopathy, modal method is exactly that the Western medicine such as long-term taking atenolol maintain the state of an illness, but long-term taking Western medicine, know from experience and bring larger side effect to people, and can not effect a radical cure.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation that can effectively treat diabetic cardiopathy, this Chinese medicine preparation determined curative effect, cheap and have no side effect.
Technical scheme of the present invention is:
A Chinese medicine preparation for the treatment of diabetic cardiopathy, is characterized in that, is made up of the crude drug of following weight parts:
The Rhizoma Anemarrhenae 9, Radix Notoginseng 12, Radix Salviae Miltiorrhizae 12, Cortex Magnoliae Officinalis 8, Cortex Moutan 8, Radix Angelicae Sinensis 6, Fructus Schisandrae Chinensis 9, Lignum Dalbergiae Odoriferae 10, Fructus Gardeniae 10, Semen Platycladi 8, Radix Asparagi 9, Fructus Trichosanthis 9, Fructus Corni 6, Fructus Aurantii Immaturus 9, Herba Epimedii 8.
Single dose dose (unit: gram): the Rhizoma Anemarrhenae 9, Radix Notoginseng 12, Radix Salviae Miltiorrhizae 12, Cortex Magnoliae Officinalis 8, Cortex Moutan 8, Radix Angelicae Sinensis 6, Fructus Schisandrae Chinensis 9, Lignum Dalbergiae Odoriferae 10, Fructus Gardeniae 10, Semen Platycladi 8, Radix Asparagi 9, Fructus Trichosanthis 9, Fructus Corni 6, Fructus Aurantii Immaturus 9, Herba Epimedii 8.
Preparation and instructions of taking: be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later, within 10 days, was a course for the treatment of.
The pharmacological action of each Chinese medicine:
The Rhizoma Anemarrhenae: bitter, sweet, cold.Return lung, stomach, kidney channel.Effect with cure mainly: clearing away heat-fire, promote the production of body fluid and moisturize.For fever caused by exogenous pathogenic factors. high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Radix Notoginseng: sweet, micro-hardship, temperature.Return liver, stomach warp.Effect with cure mainly: dissipating blood stasis hemostasis, subduing swelling and relieving pain.For spitting of blood, to spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Radix Salviae Miltiorrhizae: hardship, is slightly cold.GUIXIN, Liver Channel.Effect with cure mainly: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea , lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Cortex Magnoliae Officinalis: bitter, pungent, temperature.Return spleen, stomach, lung, large intestine channel.Effect with cure mainly: dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, stagnation of QI due to dyspepsia, and abdominal distention constipation, phlegm retention is breathed with cough.
Cortex Moutan: bitter, pungent, be slightly cold.GUIXIN, liver, kidney channel.Effect with cure mainly: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Effect with cure mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.Effect with cure mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Lignum Dalbergiae Odoriferae: pungent, temperature.Return liver, spleen channel.Effect with cure mainly: promoting flow of QI and blood, pain relieving, hemostasis.For epigastric pain, hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge, injury from falling down, traumatic hemorrhage.
Fructus Gardeniae: hardship, cold.GUIXIN, lung, tri-jiao channel.Effect with cure mainly: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, yellow cellulitis dark coloured urine, blood strangury and dry pain, heat in blood is told nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Semen Platycladi: sweet, flat.GUIXIN, kidney, large intestine channel.Effect with cure mainly: tranquilizing by nourishing the heart, hidroschesis, intestine moistening.For fidgets due to deficiency insomnia, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation.
Radix Asparagi: sweet, bitter, cold.Return lung, kidney channel.Effect with cure mainly: nourishing YIN to relieve dryness, lung heat clearing is promoted the production of body fluid.For dryness of the lung dry cough, pertussis expectorant is glutinous, dry throat and mouth, dryness of the intestine constipation.
Semen Trichosanthis: sweet, cold.Return lung, stomach, large intestine channel.Effect with cure mainly: moistening the lung and resolving phlegm, laxation relieving constipation.Glutinous for cough caused by dryness expectorant, dryness of the intestine constipation.
Fructus Corni: sour, puckery, tepor.Return liver, kidney channel.Effect with cure mainly: liver and kidney tonifying, essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, sun is passed out semen repeatly.Enuresis frequent micturition, bleeding not during menses. profuse sweating collapse, interior-heat is quenched one's thirst.
Fructus Aurantii Immaturus: bitter, pungent, sour, temperature.Return spleen, stomach warp.Effect with cure mainly: dispelling the stagnated QI removing food stagnancy, the loose painful abdominal mass of reducing phlegm.In stagnant, stop, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant, blocked-up chest; Gastroptosis, proctoptosis, uterine prolapse.
Herba Epimedii: acrid, sweet, warm.Return liver, kidney channel.Effect with cure mainly: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
The invention has the beneficial effects as follows: it is raw material that the present invention adopts natural Chinese medicine, determined curative effect and having no side effect, for the treatment of diabetic cardiopathy, total effective rate reaches 97%.
Below in conjunction with clinical trial and model case, the present invention is further described.
One, clinical trial
1, clinical data: choose at random 42-68 diabetic cardiopathy patient 100 examples in year, its mean age is 57 years old, wherein, male's 48 examples, women's 52 examples.
2, Therapeutic Method: treatment group is taken medicine of the present invention, and every day is oral meal at twice, 7 days is a course for the treatment of, takes altogether 6 courses for the treatment of.
3, efficacy assessment standard:
Effective: strengthen by treating rear body constitution, with it energetically, and feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating symptom such as overrun is obviously alleviated, and the visible scheming blood supply of electrocardiogram improves;
Effective: strengthen by treating rear body constitution, with it energetically, and feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating symptom such as overrun is alleviated and is not healed to some extent:
Invalid: after treatment, symptom is unchanged.
4, therapeutic outcome: at clinical use medicine of the present invention, the 100 routine patients that take medicine, took medicine after 3 courses for the treatment of, and symptom is alleviated to some extent, takes medicine after 6 courses for the treatment of, and symptom is obviously improved.In the routine patient of clinical trial 100, effective 75 examples, effective 22 examples, invalid 3 examples, total effective rate is 97%.
Two, model case
Case 1: Liu, female, 57 years old, suffer from diabetes 5 years, find diabetic cardiopathy half a year, cardiac insufficiency, atrial fibrillation, cardiopalmus is uncomfortable in chest, inability to breathe regularly due to shortness of breath, and dry pharynx, brings up phlegm when one coughs, fatigue and weak, edema of pair of lower extremities, dysuria.Once oral antidiabetic drug, blood glucose is still controlled bad, can't take care of oneself.Introduce and start to take Chinese medicine of the present invention through acquaintance, take medicine after 3 courses for the treatment of, the symptom such as uncomfortable in chest, to breathe hard is obviously improved, and takes medicine after 6 courses for the treatment of, and the visible blood supply of cardiac muscle of electrocardiogram also obviously improves on inspection, and the state of an illness is basicly stable, after 1 year, follows up a case by regular visits to, and the state of an illness is without recurrence.
Case 2: Tan, man, 65 years old, suffer from 8 years of diabetic cardiopathy, body constitution obviously dies down than before, and health is weak, often occur feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating symptom such as overrun, took after 4 courses for the treatment of of medicine of the present invention, above-mentioned symptom obviously improves, take medicine after 6 courses for the treatment of, energetically, the symptoms such as feeling of oppression and pain in the chest, palpitation and uneasiness disappear health substantially, drug withdrawal was followed up a case by regular visits to after 1 year, and the state of an illness is without recurrence.
Detailed description of the invention
Embodiment
Proportioning (unit: gram): the Rhizoma Anemarrhenae 9, Radix Notoginseng 12, Radix Salviae Miltiorrhizae 12, Cortex Magnoliae Officinalis 8, Cortex Moutan 8, Radix Angelicae Sinensis 6, Fructus Schisandrae Chinensis 9, Lignum Dalbergiae Odoriferae 10, Fructus Gardeniae 10, Semen Platycladi 8, Radix Asparagi 9, Fructus Trichosanthis 9, Fructus Corni 6, Fructus Aurantii Immaturus 9, Herba Epimedii 8.
Preparation and instructions of taking: be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later, within 7 days, was a course for the treatment of.

Claims (1)

1. treat a Chinese medicine preparation for diabetic cardiopathy, it is characterized in that being made by the crude drug of following weight parts: the Rhizoma Anemarrhenae 9, Radix Notoginseng 12, Radix Salviae Miltiorrhizae 12, Cortex Magnoliae Officinalis 8, Cortex Moutan 8, Radix Angelicae Sinensis 6, Fructus Schisandrae Chinensis 9, Lignum Dalbergiae Odoriferae 10, Fructus Gardeniae 10, Semen Platycladi 8, Radix Asparagi 9, Fructus Trichosanthis 9, Fructus Corni 6, Fructus Aurantii Immaturus 9, Herba Epimedii 8.
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CN104096058A (en) * 2014-07-02 2014-10-15 胥玲 Traditional Chinese medical pill for treating dilated cardiomyopathy
CN104367984A (en) * 2014-11-19 2015-02-25 伏淼 Traditional Chinese medicine formula for treating aged coronary heart disease
CN104398858A (en) * 2014-11-28 2015-03-11 唐芳刚 Traditional Chinese medicine for treating diabetic heart disease
CN106110203A (en) * 2016-08-02 2016-11-16 王昭霞 The Chinese medicine composition for the treatment of diabetic cardiopathy

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CN100542554C (en) * 2006-06-29 2009-09-23 李筱蓉 A kind of Chinese medicine composition and preparation method that is used for the treatment of type and complication

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