CN106636239B - 一种氯霉素的制备方法 - Google Patents
一种氯霉素的制备方法 Download PDFInfo
- Publication number
- CN106636239B CN106636239B CN201611007636.4A CN201611007636A CN106636239B CN 106636239 B CN106636239 B CN 106636239B CN 201611007636 A CN201611007636 A CN 201611007636A CN 106636239 B CN106636239 B CN 106636239B
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- Prior art keywords
- chloramphenicol
- reaction
- dichloroacetylation
- nitro
- preparing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (9)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201611007636.4A CN106636239B (zh) | 2016-11-16 | 2016-11-16 | 一种氯霉素的制备方法 |
PCT/CN2017/076528 WO2018086287A1 (zh) | 2016-11-11 | 2017-03-14 | 一种氯霉素类化合物的制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201611007636.4A CN106636239B (zh) | 2016-11-16 | 2016-11-16 | 一种氯霉素的制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN106636239A CN106636239A (zh) | 2017-05-10 |
CN106636239B true CN106636239B (zh) | 2019-12-31 |
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CN201611007636.4A Active CN106636239B (zh) | 2016-11-11 | 2016-11-16 | 一种氯霉素的制备方法 |
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CN (1) | CN106636239B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN111808893B (zh) * | 2019-04-10 | 2022-03-29 | 上海医药工业研究院 | 一种氨基醇类药物中间体的生物制备新方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010025238A2 (en) * | 2008-08-27 | 2010-03-04 | Codexis, Inc. | Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
WO2011022548A2 (en) * | 2009-08-19 | 2011-02-24 | Codexis, Inc. | Ketoreductase polypeptides for the preparation of phenylephrine |
CN102399161A (zh) * | 2011-12-21 | 2012-04-04 | 武汉武药科技有限公司 | 一种氯霉素的制备方法 |
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2016
- 2016-11-16 CN CN201611007636.4A patent/CN106636239B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010025238A2 (en) * | 2008-08-27 | 2010-03-04 | Codexis, Inc. | Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
WO2011022548A2 (en) * | 2009-08-19 | 2011-02-24 | Codexis, Inc. | Ketoreductase polypeptides for the preparation of phenylephrine |
CN102399161A (zh) * | 2011-12-21 | 2012-04-04 | 武汉武药科技有限公司 | 一种氯霉素的制备方法 |
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Publication number | Publication date |
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CN106636239A (zh) | 2017-05-10 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of chloramphenicol Effective date of registration: 20210222 Granted publication date: 20191231 Pledgee: Changde finance finance Company limited by guarantee Pledgor: SUZHOU LEAD BIOTECHNOLOGY Co.,Ltd. Registration number: Y2021980001248 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20220826 Granted publication date: 20191231 Pledgee: Changde finance finance Company limited by guarantee Pledgor: SUZHOU LEAD BIOTECHNOLOGY Co.,Ltd. Registration number: Y2021980001248 |