CN106619592A - Medicine for treating acute pharyngitis - Google Patents

Medicine for treating acute pharyngitis Download PDF

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Publication number
CN106619592A
CN106619592A CN201611023827.XA CN201611023827A CN106619592A CN 106619592 A CN106619592 A CN 106619592A CN 201611023827 A CN201611023827 A CN 201611023827A CN 106619592 A CN106619592 A CN 106619592A
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CN
China
Prior art keywords
parts
medicine
pharyngitises
cefalexin
vitamin
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611023827.XA
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Chinese (zh)
Inventor
不公告发明人
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Zhengzhou Zhengxian Pharmaceutical Technology Co Ltd
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Zhengzhou Zhengxian Pharmaceutical Technology Co Ltd
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Priority to CN201611023827.XA priority Critical patent/CN106619592A/en
Publication of CN106619592A publication Critical patent/CN106619592A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/191Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/41521,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Abstract

The invention discloses a medicine for treating acute pharyngitis. The medicine for treating the acute pharyngitis is prepared from the following main raw materials in parts by weight: 5 to 12 parts of cefalexin, 8 to 15 parts of methimazole, 13 to 18 parts of vitamin E, 5 to 9 parts of phenprobamate, 11 to 16 parts of analginum, 2 to 6 parts of calcium gluconate, 4 to 10 parts of acyclovir and 5 to 8 parts of bromhexine hydrochloride. The medicine disclosed by the invention is used for treating the acute pharyngitis; the medicine is convenient to take, small in side effect, has the effects of clearing heat and relieving sore throat, and has the major function of treating the acute pharyngitis; practical inspection shows that the medicine has an obvious relieving effect on the acute pharyngitis.

Description

A kind of medicine for treating acute pharyngitises
Technical field
The present invention relates to a kind of field of medicine preparation, specifically a kind of medicine for treating acute pharyngitises.
Background technology
Pharyngolaryngitis, are a kind of diseases caused by antibacterial and virus, can be divided into two kinds of acute pharyngolaryngitises and chronic pharyngolaryngitiss. Acute pharyngolaryngitises winter-spring season is the most common, is secondary to acute rhinitises, acute sinusitis, acute tonsillitiss more, and is often measles, The complication of the infectious disease such as influenza, scarlet fever, adult based on pharyngeal symptom, disease is just pharyngeal have it is dry itch, it is scorching hot, gradually have pain Bitterly, increase when swallowing, excessive saliva, lateral pharyngeal band involvement then has obvious otalgia, General Symptomies significantly, have fever cold, headache, The symptoms such as inappetence, extremities aching pain;Chronic pharyngitiss be due to acute pharyngitises treatment not thorough recurrent exerbation, switch to it is chronic, Or because suffering from various cacorhinias, nose key obstruction, caused by long-term mouth breathing, the various chronic diseases of whole body, such as anemia, constipation, under Respiratory tract chronic inflammation, cardiovascular disease etc. also can secondary primary disease, patient feels pharyngeal discomfort, does, itches, swollen, secretions it is many and Causalgia, there is a foreign body sensation, and above symptom is being spoken slightly many, after edible irritable food, fatigue or is increased during Changes in weather.Treatment pharynx Laryngitis has various methods, such as tea therapy, dietetic therapy, western medicine, treatment by Chinese herbs.And traditional remedies are not suitable for the treatment of acute pharyngitises, Need the western medicine medicine that a kind of Small side effects, curative effect are fast.
The content of the invention
It is an object of the invention to provide a kind of medicine for treating acute pharyngitises, to solve above-mentioned background technology in propose Problem.
For achieving the above object, the present invention provides following technical scheme:
A kind of medicine for treating acute pharyngitises, be according to the primary raw material of weight portion:Cefalexin 5-12 part, thiamazole 8-15 parts, Vitamin E 13-18 part, phenprobamate 5-9 parts, dipyrone 11-16 parts, calcium gluconate 2-6 parts, acyclovir 4- 10 parts, Bisolvon 5-8 parts.
As further scheme of the invention:The medicine of the treatment acute pharyngitises, be according to the primary raw material of weight portion: Cefalexin 6-10 part, thiamazole 10-14 parts, Vitamin E 14-16 part, phenprobamate 5-9 parts, dipyrone 13-15 parts, Portugal Grape Calciofon 2-6 parts, acyclovir 5-9 parts, Bisolvon 5-8 parts.
As further scheme of the invention:The medicine of the treatment acute pharyngitises, be according to the primary raw material of weight portion: 8 parts of Cefalexin, 12 parts of thiamazole, 15 parts of Vitamin E, 8 parts of phenprobamate, 14 parts of dipyrone, 4 parts of calcium gluconate, Ah 8 parts of VCV, 7 parts of Bisolvon.
A kind of preparation method of the medicine for treating acute pharyngitises, concretely comprises the following steps:
First, in pharmaceutical grade clean area, Cefalexin, thiamazole, Vitamin E, phenylpropyl alcohol are weighed by above-mentioned metering ratio Urethane, dipyrone, calcium gluconate, acyclovir, Bisolvon, sieve, and machinery adds ultra-pure water after mixing, and place pharmacy In mixer, mix 4-8min, control RSD≤5%, tabletting and cold drying after mixing, at 4-8 DEG C, packaging is temperature control The medicine of acute pharyngitises must be treated.
As further scheme of the invention:Mix 6min in concrete steps.
As further scheme of the invention:Temperature control is at 6 DEG C in concrete steps.
Compared with prior art, the invention has the beneficial effects as follows:
Product of the present invention is used for the treatment of acute pharyngolaryngitises, and the drug administration is convenient, Small side effects, with relieving sore-throat by clearing away heat Effect, cures mainly acute pharyngitises, and Jing practice tests have obvious mitigation to acute pharyngitises.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the invention, rather than the embodiment of whole.Based in the present invention Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, all Belong to the scope of protection of the invention.
Embodiment 1
A kind of medicine for treating acute pharyngitises, be according to the primary raw material of weight portion:5 parts of Cefalexin, thiamazole 8 Part, 13 parts of Vitamin E, 5 parts of phenprobamate, 11 parts of dipyrone, 2 parts of calcium gluconate, 4 parts of acyclovir, Bisolvon 5 Part.
A kind of preparation method of the medicine for treating acute pharyngitises, concretely comprises the following steps:
First, in pharmaceutical grade clean area, Cefalexin, thiamazole, Vitamin E, phenylpropyl alcohol are weighed by above-mentioned metering ratio Urethane, dipyrone, calcium gluconate, acyclovir, Bisolvon, sieve, and machinery adds ultra-pure water after mixing, and place pharmacy In mixer, mix 4min, control RSD≤5%, tabletting and cold drying after mixing, at 4 DEG C, packaging is obtained final product to be controlled temperature control Treat the medicine of acute pharyngitises.
Embodiment 2
A kind of medicine for treating acute pharyngitises, be according to the primary raw material of weight portion:6 parts of Cefalexin, thiamazole 10 Part, 14 parts of Vitamin E, 5 parts of phenprobamate, 13 parts of dipyrone, 2 parts of calcium gluconate, 5 parts of acyclovir, Bisolvon 5 Part.
A kind of preparation method of the medicine for treating acute pharyngitises, concretely comprises the following steps:
First, in pharmaceutical grade clean area, Cefalexin, thiamazole, Vitamin E, phenylpropyl alcohol are weighed by above-mentioned metering ratio Urethane, dipyrone, calcium gluconate, acyclovir, Bisolvon, sieve, and machinery adds ultra-pure water after mixing, and place pharmacy In mixer, mix 4min, control RSD≤5%, tabletting and cold drying after mixing, at 4 DEG C, packaging is obtained final product to be controlled temperature control Treat the medicine of acute pharyngitises.
Embodiment 3
A kind of medicine for treating acute pharyngitises, be according to the primary raw material of weight portion:8 parts of Cefalexin, thiamazole 12 Part, 15 parts of Vitamin E, 8 parts of phenprobamate, 14 parts of dipyrone, 4 parts of calcium gluconate, 8 parts of acyclovir, Bisolvon 7 Part.
A kind of preparation method of the medicine for treating acute pharyngitises, concretely comprises the following steps:
First, in pharmaceutical grade clean area, Cefalexin, thiamazole, Vitamin E, phenylpropyl alcohol are weighed by above-mentioned metering ratio Urethane, dipyrone, calcium gluconate, acyclovir, Bisolvon, sieve, and machinery adds ultra-pure water after mixing, and place pharmacy In mixer, mix 6min, control RSD≤5%, tabletting and cold drying after mixing, at 6 DEG C, packaging is obtained final product to be controlled temperature control Treat the medicine of acute pharyngitises.
Embodiment 4
A kind of medicine for treating acute pharyngitises, be according to the primary raw material of weight portion:10 parts of Cefalexin, thiamazole 14 Part, 16 parts of Vitamin E, 9 parts of phenprobamate, 15 parts of dipyrone, 6 parts of calcium gluconate, 9 parts of acyclovir, Bisolvon 8 Part.
A kind of preparation method of the medicine for treating acute pharyngitises, concretely comprises the following steps:
First, in pharmaceutical grade clean area, Cefalexin, thiamazole, Vitamin E, phenylpropyl alcohol are weighed by above-mentioned metering ratio Urethane, dipyrone, calcium gluconate, acyclovir, Bisolvon, sieve, and machinery adds ultra-pure water after mixing, and place pharmacy In mixer, mix 8min, control RSD≤5%, tabletting and cold drying after mixing, at 8 DEG C, packaging is obtained final product to be controlled temperature control Treat the medicine of acute pharyngitises.
Embodiment 5
A kind of medicine for treating acute pharyngitises, be according to the primary raw material of weight portion:12 parts of Cefalexin, thiamazole 15 Part, 18 parts of Vitamin E, 9 parts of phenprobamate, 16 parts of dipyrone, 6 parts of calcium gluconate, 10 parts of acyclovir, Bisolvon 8 Part.
A kind of preparation method of the medicine for treating acute pharyngitises, concretely comprises the following steps:
First, in pharmaceutical grade clean area, Cefalexin, thiamazole, Vitamin E, phenylpropyl alcohol are weighed by above-mentioned metering ratio Urethane, dipyrone, calcium gluconate, acyclovir, Bisolvon, sieve, and machinery adds ultra-pure water after mixing, and place pharmacy In mixer, mix 8min, control RSD≤5%, tabletting and cold drying after mixing, at 8 DEG C, packaging is obtained final product to be controlled temperature control Treat the medicine of acute pharyngitises.
Medicine Jing acute and chronic toxicology tests prepared by embodiment of the present invention 1-5, without discovery toxic reaction.
Using method:
Take once every 4 hours warm water, each 2g, until recovery from illness.
Model case:
Wang, female, 21 years old, pharyngeal causalgia 8 hours, and there is low grade fever, and dry pharynx cough, diagnosis:Acute pharyngitises.Using this Medicine prepared by bright embodiment 3, after taking once, starts effective, symptom all disappearances after 8 hours after 4 hours.
Wu, man, 35 years old, pharyngeal causalgia 10 hours, and there is sputum band blood, and pronounce hoarse, diagnosis:Acute pharyngitises.Make With the embodiment of the present invention 3 prepare medicine, after taking once, symptom slows down, and takes again, start after 4 hours it is effective, 8 hours Afterwards symptom all disappears.
Liu, female, 47 years old, throat causalgia 6 hours, and occur swallowing pain, cough but no phlegm, diagnosis:Acute pharyngitises.Use The embodiment of the present invention 3 prepare medicine, after taking once, symptom slows down, and takes again, start after 6 hours it is effective, after 10 hours Symptom all disappears.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of spirit or essential attributes without departing substantially from the present invention, the present invention can be in other specific forms realized.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling Change is included in the present invention.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of description is only that for clarity those skilled in the art should Using description as an entirety, the technical scheme in each embodiment can also Jing it is appropriately combined, form those skilled in the art Understandable other embodiment.

Claims (6)

1. a kind of medicine for treating acute pharyngitises, it is characterised in that the primary raw material according to weight portion is:Cefalexin 5-12 Part, thiamazole 8-15 parts, Vitamin E 13-18 part, phenprobamate 5-9 parts, dipyrone 11-16 parts, calcium gluconate 2-6 Part, acyclovir 4-10 parts, Bisolvon 5-8 parts.
2. it is according to claim 1 treatment acute pharyngitises medicine, it is characterised in that the medicine of the treatment acute pharyngitises Thing, be according to the primary raw material of weight portion:Cefalexin 6-10 part, thiamazole 10-14 parts, Vitamin E 14-16 part, phenylpropyl alcohol Urethane 5-9 part, dipyrone 13-15 parts, calcium gluconate 2-6 parts, acyclovir 5-9 parts, Bisolvon 5-8 parts.
3. it is according to claim 1 and 2 treatment acute pharyngitises medicine, it is characterised in that the treatment acute pharyngitises Medicine, be according to the primary raw material of weight portion:8 parts of Cefalexin, 12 parts of thiamazole, 15 parts of Vitamin E, phenprobamate 8 Part, 14 parts of dipyrone, 4 parts of calcium gluconate, 8 parts of acyclovir, 7 parts of Bisolvon.
4. a kind of preparation method of the medicine of the treatment acute pharyngitises as described in claim 1-3 is arbitrary, it is characterised in that concrete Step is:
First, in pharmaceutical grade clean area, by above-mentioned metering ratio weigh Cefalexin, thiamazole, Vitamin E, phenprobamate, Dipyrone, calcium gluconate, acyclovir, Bisolvon, sieve, and machinery adds ultra-pure water after mixing, and place pharmacy mixing In machine, mix 4-8min, control RSD≤5%, tabletting and cold drying after mixing, at 4-8 DEG C, packaging is obtained final product to be controlled temperature control Treat the medicine of acute pharyngitises.
5. it is according to claim 4 treatment acute pharyngitises medicine preparation method, it is characterised in that in concrete steps mix Close 6min.
6. it is according to claim 4 treatment acute pharyngitises medicine preparation method, it is characterised in that the middle temperature of concrete steps Degree control is at 6 DEG C.
CN201611023827.XA 2016-11-17 2016-11-17 Medicine for treating acute pharyngitis Pending CN106619592A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611023827.XA CN106619592A (en) 2016-11-17 2016-11-17 Medicine for treating acute pharyngitis

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Application Number Priority Date Filing Date Title
CN201611023827.XA CN106619592A (en) 2016-11-17 2016-11-17 Medicine for treating acute pharyngitis

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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CN1424084A (en) * 2002-12-19 2003-06-18 中国人民解放军第二军医大学 Honeysuckle flower and coptis root powder injection and its preparing method
CN101340902A (en) * 2005-11-28 2009-01-07 奥加生物药业(香港)有限公司 Materials and methods for treating viral infections with a cysteamine compound
CN101466716A (en) * 2006-04-07 2009-06-24 德维洛根股份公司 Thienopyrimidines having MNKL/MNK2 inhibiting activity for pharmaceutical compositions
CN101912368A (en) * 2010-09-26 2010-12-15 上海理工大学 Compound cefaclor suspension and preparation method thereof
CN104107171A (en) * 2014-01-22 2014-10-22 邓学峰 Cefradine composition
CN105851758A (en) * 2016-05-18 2016-08-17 何凤祥 Amino acid drink

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020160491A1 (en) * 2000-01-28 2002-10-31 Jian Ni Human Serpin polynucleotides, polypeptides, and antibodies
CN1424084A (en) * 2002-12-19 2003-06-18 中国人民解放军第二军医大学 Honeysuckle flower and coptis root powder injection and its preparing method
CN101340902A (en) * 2005-11-28 2009-01-07 奥加生物药业(香港)有限公司 Materials and methods for treating viral infections with a cysteamine compound
CN101466716A (en) * 2006-04-07 2009-06-24 德维洛根股份公司 Thienopyrimidines having MNKL/MNK2 inhibiting activity for pharmaceutical compositions
CN101912368A (en) * 2010-09-26 2010-12-15 上海理工大学 Compound cefaclor suspension and preparation method thereof
CN104107171A (en) * 2014-01-22 2014-10-22 邓学峰 Cefradine composition
CN105851758A (en) * 2016-05-18 2016-08-17 何凤祥 Amino acid drink

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Title
王兰等: "咽立爽治疗急性咽炎的疗效观察", 《山东医大基础医学院学报》 *

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Application publication date: 20170510