CN106492018A - A kind of Chinese medicine composition for treating insomnia and preparation method thereof - Google Patents

A kind of Chinese medicine composition for treating insomnia and preparation method thereof Download PDF

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CN106492018A
CN106492018A CN201611016851.0A CN201611016851A CN106492018A CN 106492018 A CN106492018 A CN 106492018A CN 201611016851 A CN201611016851 A CN 201611016851A CN 106492018 A CN106492018 A CN 106492018A
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chinese medicine
radix
medicine composition
raw material
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邹赢锌
巨大维
储智勇
冯旭
陈松
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Navy Medicine Research Institute of PLA
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Abstract

The present invention relates to a kind of Chinese medicine composition for treating insomnia and preparation method thereof, the raw material of Chinese medicine of the Chinese medicine composition includes:9 25 parts of Semen Ziziphi Spinosae, 9 18 parts of Radix Polygalae, 12 30 parts of Radix Codonopsis, 12 30 parts of the Radix Astragali, 9 18 parts of Radix Angelicae Sinensis, 6 12 parts of Arillus Longan, 6 15 parts of Radix Bupleuri, 9 18 parts of the Radix Paeoniae Alba, 6 12 parts of Poria cum Radix Pini, 6 12 parts of Herba Lophatheri, 6 12 parts of Semen Platycladi, 6 15 parts of Radix Glycyrrhizae;Its preparation method is to weigh Chinese crude drug, is mixed in proportion and is ground into granule;Immersion and/or decoction, by extracting solution heating concentration;Prepare fluid extract;It is spray-dried powder processed.Compared with prior art, Chinese medicine composition of the present invention, its preparation method is simple, each compatibility of drugs rationally, effect clearly, have no adverse reaction, there is tranquilize the mind and promote the intelligence, vigorate qi and replenish the blood, clearing heat and relieving fidgetness, evident in efficacy in terms for the treatment of deficiency of vital energy insomnia, it is particularly suited for the treatment of Chief Petty Officer's oceangoing voyage officers and men insomnia.

Description

A kind of Chinese medicine composition for treating insomnia and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, and in particular to a kind of Chinese medicine composition for treating insomnia and its preparation side Method.
Background technology
Insomnia refers to that patient is unsatisfactory on the length of one's sleep and (or) quality and affects a kind of subjective body of social function in the daytime Test.The clinical manifestation of insomnia includes sleep procedure obstacle, and such as difficulty falling asleep, sleep quality decline and the length of one's sleep is reduced etc.;Day Between cognitive dysfunction, such as memory function decline, aprosexia, spiritlessness and weakness etc.;Cerebral limbic system and its plant of surrounding The disorder of thing nervous dysfunction, such as cardiovascular system, digestive system disorder, emotion control reduced capability etc..
Although the medicine species of clinical treatment insomnia at present is various, the main usess of most drug are not that treatment is lost Sleep, and simply there is syngignoscism, all kinds of Western medicine have a certain degree of toxic and side effects, easy infringement liver after taking Kidney, causes gastrointestinal upset, dizzy, weak, vomiting, diarrhoea and a series of allergic conditions occurs, and its Time of Administration is long, Some medicines have additive, easily recur after deactivation, it is impossible to thoroughly effect a radical cure.
China's Chinese Traditional Medicine has good curative effect in terms for the treatment of insomnia.Insomnia is referred to as " being insomnia ", the traditional Chinese medical science in the traditional Chinese medical science Also there are the titles such as " must not crouch ", " insomnia ", " unable to close the eyes ", " sleeplessness ", " sleeping less " in ancient books.The traditional Chinese medical science is classified as in mental diseases A kind of common disease.The traditional Chinese medical science has 3 principles to the treatment having a sleepless night:One is adjustment internal organs yang blood and qi.Internal organs imbalance of YIN and YANG, gas Blood become estranged so that malaise and be insomnia, therefore answer invigorating the heart and spleen, soothing liver-QI blood-nourishing, QI invigorating is relieving convulsion.Two is tranquilizing the mind.The disease being insomnia Machine it is critical only that irritability, thus answer blood-nourishing to clear away heart-fire, QI invigorating supplementing the brain.Three is to strengthen psychotherapy.Feelings will is not relaxed, overanxiexty etc. Mental symptom is the common factors for causing to be insomnia, therefore answers soothing liver-QI for relieving depression, easing the affected liver blood-nourishing.And Chinese medicine species is various, the monarch drug of employing, Ministerial drug, adjuvant drug, the type of feed for making medicine and proportioning are different, and its curative effect difference is very big, and different the reason for cause insomnia, which adopts Medicine is also not quite similar, and how to select the Chinese medicine formula of excellent treatment effect according to particular condition to the treatment had a sleepless night and human body Health is all highly important.
Content of the invention
Present invention is primarily targeted at overcoming defect of the prior art, there is provided a kind of Chinese medicine composition for treating insomnia And preparation method thereof, mainly for the insomnia that the treatment deficiency of vital energy causes.
For achieving the above object, the present invention is adopted the following technical scheme that:
On the one hand, the present invention provides a kind of Chinese medicine composition for treating insomnia, and its raw material of Chinese medicine and weight proportion are:
Semen Ziziphi Spinosae 9-25 parts, Radix Polygalae 9-18 part, Radix Codonopsis 12-30 parts, Radix Astragali 12-30 parts, Radix Angelicae Sinensis 9-18 parts, Arillus Longan 6-12 Part, Radix Bupleuri 6-15 parts, Radix Paeoniae Alba 9-18 parts, Poria cum Radix Pini's 6-12 parts, Herba Lophatheri 6-12 parts, Semen Platycladi 6-12 parts, Radix Glycyrrhizae 6-15 parts.
Preferably, the raw material of Chinese medicine and weight proportion of the Chinese medicine composition is:
20 parts of Semen Ziziphi Spinosae, 15 parts of Radix Polygalae, 20 parts of Radix Codonopsis, 20 parts of the Radix Astragali, 15 parts of Radix Angelicae Sinensis, 9 parts of Arillus Longan, 9 parts of Radix Bupleuri, the Radix Paeoniae Alba 15 parts, 9 parts of Poria cum Radix Pini, 6 parts of Herba Lophatheri, 9 parts of Semen Platycladi, 9 parts of Radix Glycyrrhizae.
The Chinese medicine composition for the treatment of insomnia of the present invention fully follows the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs principle of the traditional Chinese medical science, particular for gas Void is had a sleepless night and is invented.The effect of this Chinese medicine composition has tranquilize the mind and promote the intelligence, vigorate qi and replenish the blood, clearing heat and relieving fidgetness.We reuse Semen Ziziphi Spinosae Mind tranquilizing and the heart calming, for controlling the key medicine of restlessness of asrhenia type and insomnia, is the monarch drug of we;Radix Codonopsis, Radix Astragali invigorating the spleen and replenishing QI, blood-nourishing consolidating superficial resistance, are we's Ministerial drug;Chinese angelica blood supplementing is invigorated blood circulation, and Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver, Herba Lophatheri clearing heat and relieving fidgetness, Radix Polygalae eliminating the phlegm are had one's ideas straightened out, Poria cum Radix Pini Mind tranquilizing and the heart calming, Arillus Longan reinforcing the heart spleen, replenishing QI and blood, Semen Platycladi loosening bowel to relieve constipation are adjuvant drug altogether.Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription is to make medicine.All medicine phases Close, not only mind tranquilizing and the heart calming, nourishing qi and blood but also clearing heat and relieving fidgetness, close the disease for controlling deficiency of vital energy sleeplessness.We follow above-mentioned traditional Chinese medicine in treating insomnia 3 principles, rationally, therapeutic effect is satisfied with compatibility of drugs.
Semen Ziziphi Spinosae:Sweet, sour, flat.GUIXIN, liver, gallbladder meridian.There is tranquilizing by nourishing the heart, arresting sweating.
Radix Codonopsis:Sweet, flat.Returns spleen, lung meridian.There is invigorating the spleen and replenishing QI, blood-nourishing.Modern study shows that Radix Codonopsis can be adjusted Central nervous system, improves memory function.
The Radix Astragali:Sweet, tepor.Returns spleen, lung meridian.There is the effects such as invigorating QI to consolidate the body surface resistance, detoxification evacuation of pus granulation promoting, diuresis.Modern study Show, the Radix Astragali has calm, analgesia and hypermnesis effect.
Radix Polygalae:Acrid, bitter, warm.GUIXIN, kidney, lung meridian.There is tranquilize the mind and promote the intelligence, eliminating the phlegm to have one's ideas straightened out, subduing inflammation.
Radix Bupleuri:Bitter, be slightly cold.Return liver, gallbladder meridian.There is reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI, clearing gallbladder preventing the attack (or recurrence) of malaria, ascending up spleen-Qi and Yang.
The Radix Paeoniae Alba:Bitter, acid, it is slightly cold.Return liver, spleen channel.There is blood-nourishing yin fluid astringing, easing the affected liver to relieve pain, suppressing liver-YANG.
Radix Angelicae Sinensis:Sweet, pungent, warm.Return liver, the heart, spleen channel.There is replenishing and activating blood, pain relieving, intestine moistening.
Arillus Longan:Sweet, warm.GUIXIN, spleen channel.There is reinforcing the heart spleen, replenishing QI and blood, cure mainly deficiency of both the heart and spleen, palpitation with fear, lose Dormancy, forgetful, insufficiency of vital energy and blood.
Poria cum Radix Pini:Sweet, light, flat.GUIXIN, spleen, stomach, kidney channel.There is mind tranquilizing and the heart calming, promoting diuresis to eliminate damp pathogen, invigorating middle warmer spleen invigorating.With Semen Ziziphi Spinosae, Radix Polygalae collocation, mind tranquilizing and the heart calming effect are more preferable.
Herba Lophatheri:Sweet, light, cold.GUIXIN, stomach, small intestine meridian.There is heat clearing away, relieving restlessness, diuresis.Cure mainly the heart after calentura Tired, thirsty, aphtha of the mouth and tongue, toothache, urine burning pain.
Semen Platycladi:Sweet, flat.GUIXIN, liver, large intestine channel.There is tranquilizing by nourishing the heart, loosening bowel to relieve constipation.Cure mainly palpitation and insomnia, Dry constipation of intestines.
Radix Glycyrrhizae:Sweet, flat.GUIXIN, lung, spleen, stomach.There is invigorating middle warmer and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, tune Effect with all medicines.
On the other hand, the present invention provides a kind of preparation method of the Chinese medicine composition for treating insomnia, described preparation method Including following three kinds:
The first preparation method:
Step one, raw material of Chinese medicine as claimed in claim 1 is weighed, be mixed in proportion, and by mixed raw material of Chinese medicine It is ground into granule;
Step 2, by the feed particles obtained by step one with ethanol soak, reflux, extract, 2 times, merge alcohol extract, raw material Medicinal residues are standby;
Step 3, the raw material medicinal residues described in step 2 are boiled with decocting, decocted 2 times, merge decocting liquid;
Step 4, in the decocting liquid described in step 3,98% ethanol is added, which is heated and is concentrated into determining alcohol 70%, made Obtain Aqueous extracts;
Step 5, the alcohol extract described in step 2 and the Aqueous extracts described in step 4 are merged into mixed liquor, to mixed liquor Reduced pressure to reclaim alcohol solvent, and mixed liquor concentration is prepared fluid extract;
Step 6, the fluid extract obtained by step 5 is spray-dried, obtains and contain Chinese medicine composition effective ingredient Dry powder.
Second preparation method:
Step one, raw material of Chinese medicine as claimed in claim 1 is weighed, be mixed in proportion, and by mixed raw material of Chinese medicine It is ground into granule;
Step 2, by the feed particles obtained by step one with ethanol soak, reflux, extract, 2 times, merge alcohol extract,
Step 3, the alcohol extract described in step 2 is reduced pressure to reclaim alcohol solvent, and be prepared by alcohol extract concentration Fluid extract;
Step 4, the fluid extract obtained by step 3 is spray-dried, obtains and contain Chinese medicine composition effective ingredient Dry powder.
The third preparation method:
Step one, raw material of Chinese medicine as claimed in claim 1 is weighed, be mixed in proportion, and by mixed raw material of Chinese medicine It is ground into granule;
Step 2, by the feed particles obtained by step one with water soak 1~2h;
Step 3, the immersion raw material in step 2 is boiled with decocting, decocted 2 times, merge decocting liquid;
Step 4, by obtained by step 3 decocting liquid heating concentration prepare fluid extract;
Step 5, the fluid extract obtained by step 4 is spray-dried, obtains and contain Chinese medicine composition effective ingredient Dry powder.
Preferably, in the first preparation method described and second preparation method, in step 2, concentration of alcohol is 70- 80%, soak time is 1.5-2.5h.
Preferably, in the first preparation method described and the third preparation method, the water yield is decocted for raw material in step 3 6-10 times, decocting time is 40-70min.
Preferably, in the first preparation method described, second preparation method and the third preparation method, the fluid extract Relative density be 1.15-1.35 (35 DEG C).
Finally, the present invention also provides a kind of application of Chinese medicine composition in medicament for treating insomnia is prepared, and by treating The Chinese medicine composition of effective dose and the preparation made by pharmaceutically acceptable pharmaceutic adjuvant.
The preparation of the preparation adopts conventional fabrication process, by fluid extract obtained in Chinese medicine composition of the present invention or Dry powder selects suitable adjuvant by this area Conventional wisdom, the dosage form needed for being obtained according to a conventional method, such as granule, oral liquid, Capsule, tablet, pill, syrup, teabag etc..
Compared with prior art, the invention has the advantages that:The Chinese medicine composition for the treatment of insomnia of the present invention Thing, rationally, effect clearly, has no adverse reaction each material medicine compatibility, and without drug dependence, and preparation method is simple.The present invention The Chinese medicine composition has functions that tranquilize the mind and promote the intelligence, vigorate qi and replenish the blood, clearing heat and relieving fidgetness, it is adaptable to the treatment of deficiency of vital energy insomnia, especially It is applied to the treatment of Chief Petty Officer's oceangoing voyage officers and men insomnia.
Specific embodiment
With reference to embodiment, the specific embodiment of the present invention is further described.Following examples are only used for more Plus technical scheme is clearly demonstrated, and can not be limited the scope of the invention with this.
Embodiment one
A kind of Chinese medicine composition for treating insomnia, its raw material of Chinese medicine and weight proportion are:Semen Ziziphi Spinosae 20g, Radix Polygalae 15g, party Ginseng 20g, Radix Astragali 20g, Radix Angelicae Sinensis 15g, Arillus Longan 9g, Radix Bupleuri 9g, Radix Paeoniae Alba 15g, Poria cum Radix Pini 9g, Herba Lophatheri 6g, Semen Platycladi 9g, Radix Glycyrrhizae 9g.
Preparation method is as follows:(1) Chinese crude drug is weighed, is mixed in proportion;(2) granule is ground into;(3) with 70- 80% ethanol soaks 1.5-2.5h;(4) reflux, extract, 2 times, merge alcohol extract;(5) filtration medicinal residues boil 40- with 6-10 times of decocting 70min, decocts 2 times, merges decocting liquid, and heating concentration adds 98% ethanol to determining alcohol 70%;(6) alcohol extract and water are merged Extract, decompression recycling ethanol solvent are concentrated into the fluid extract that relative density is 1.15-1.35 (35 DEG C);(7) it is spray-dried, obtains Obtain the dry powder of Chinese medicine composition effective ingredient of the present invention.
Embodiment two
A kind of Chinese medicine composition for treating insomnia, its raw material of Chinese medicine and weight proportion are with embodiment one.
Preparation method is as follows:(1) Chinese crude drug is weighed, is mixed in proportion;(2) granule is ground into;(3) 70-80% Ethanol soaks 1.5-2.5h;(4) reflux, extract, 2 times, merge alcohol extract;(5) decompression recycling ethanol solvent, is concentrated into relative density Fluid extract for 1.15-1.35 (35 DEG C);(6) it is spray-dried, obtains the alcohol extracting thing effective ingredient of Chinese medicine composition of the present invention Dry powder.
Embodiment three
A kind of Chinese medicine composition for treating insomnia, its raw material of Chinese medicine and weight proportion are with embodiment one.
Preparation method is as follows:(1) Chinese crude drug is weighed, is mixed in proportion;(2) granule is ground into;(3) soaked with water 2-3h;(4) 6-10 times of decocting boils 40-70min, decocts 2 times;(5) merge decocting liquid, heating is concentrated into relative density 1.15- 1.35(35℃);(6) it is spray-dried, obtains the dry powder of the water extract effective ingredient of Chinese medicine composition of the present invention.
Example IV
A kind of Chinese medicine composition for treating insomnia, its raw material of Chinese medicine and weight proportion are:Semen Ziziphi Spinosae 9g, Radix Polygalae 9g, Radix Codonopsis 12g, Radix Astragali 12g, Radix Angelicae Sinensis 9g, Arillus Longan 6g, Radix Bupleuri 6g, Radix Paeoniae Alba 9g, Poria cum Radix Pini 6g, Herba Lophatheri 6g, Semen Platycladi 6g, Radix Glycyrrhizae 6g.
Preparation method step is with embodiment one.
Embodiment five
A kind of Chinese medicine composition for treating insomnia, its raw material of Chinese medicine and weight proportion are:Semen Ziziphi Spinosae 12g, Radix Polygalae 9g, Radix Codonopsis 18g, Radix Astragali 18g, Radix Angelicae Sinensis 9g, Arillus Longan 12g, Radix Bupleuri 15g, Radix Paeoniae Alba 18g, Poria cum Radix Pini 12g, Herba Lophatheri 9g, Semen Platycladi 9g, Radix Glycyrrhizae 15g.
Preparation method step is with embodiment one.
Embodiment six
A kind of preparation prepared using Chinese medicine composition of the present invention
Capsule:The active dry powder of the Chinese medicine composition prepared by embodiment one is crushed, mixes, loads gelatin hard Capsule.
Tablet:The active component dry powder of the Chinese medicine composition prepared by embodiment one is crushed, is mixed, adding adjuvant to make Granule, drying, tabletted.
Granule:The active component dry powder of the Chinese medicine composition prepared by embodiment one is crushed, is mixed, adding ethanol to make For binding agent, add starch as filler, be pressed into granule.
Embodiment seven
Patient 128, wherein man 57, female 71, age 18-52 year, the course of disease 2 weeks to 1.5 years.The lighter falls asleep tired Easily wake up after difficult or sleep, severe one is lain awake all night, and is often accompanied by the diseases such as dreaminess, forgetful, hypomnesis, lustreless complexion, through clinical inspection Look into each system no abnormal.The Chinese medicine capsules oral 3 times daily of the application embodiment of the present invention one, each 3-6 grains 15 days are One course for the treatment of, continuously with after the 2-3 course for the treatment of, therapeutic effect see the table below:
In therapeutic process, untoward reaction is had no.Model case is as follows:
1 Lee of case ×, man, 32 years old, workman, pale complexion, short breath, spiritlessness and too weak to speak, dizziness, dysphoria insomnia, asthenia Lack of appetite, insomnia forgetfulness are had a surplus for 1 year, with pale tongue fat tender, have indentation.After taking this medicine 7 days, sleep quality is substantially good Turn, appetite recovers normal, dizzy fidgets due to deficiency symptom mitigation.
2 Zhai's ×× of case, man, 39 years old, soldier, because being busy with one's work, mental burden weight causes dreaminess to have a sleepless night, daily sleep 3-5 hours, next day spiritlessness and weakness, hypomnesis, while partially dry, not well after an action of the bowels with mood agitation, stool.Through taking this medicine After 10 days, it is relieved up to 6-8 hours, dreaminess phenomenon the length of one's sleep, spiritlessness and weakness phenomenon disappears, stool is normal.
Case 3 applies ××, female, and 44 years old, housewife thought much on ordinary days, is apt to melancholy irritability, and insomnia forgetfulness is had a surplus with exhaling for 3 years Air-breathing is short, enlarged tongue has indentation.After taking this medicine 15 days, phenomenon is clearly better, hyoid tooth trace substantially mitigates for insomnia, it is normal to breathe, Spiritual optimism.
Above-described embodiment understands that the Chinese medicine composition for the treatment of insomnia of the present invention, each material medicine compatibility rationally, are made With clear and definite, have no adverse reaction, without drug dependence, and preparation method is simple.Chinese medicine composition of the present invention has benefit of calming the nerves Intelligence, vigorate qi and replenish the blood, effect of clearing heat and relieving fidgetness, it is adaptable to the treatment of deficiency of vital energy insomnia, are particularly suited for Chief Petty Officer's oceangoing voyage officers and men insomnia Treatment.
Above the specific embodiment of the present invention is described in detail, but which has been only used as example, the present invention has been not intended to limit In particular embodiments described above.To those skilled in the art, any equivalent modifications carried out by the practicality and replace In generation, is also all among scope of the invention.Therefore, the equalization that is made without departing from the spirit and scope of the invention is converted and is repaiied Change, should all cover within the scope of the invention.

Claims (10)

1. a kind of Chinese medicine composition for treating insomnia, it is characterised in that the raw material of Chinese medicine and weight proportion of the Chinese medicine composition For:
Semen Ziziphi Spinosae 9-25 parts, Radix Polygalae 9-18 part, Radix Codonopsis 12-30 parts, Radix Astragali 12-30 parts, Radix Angelicae Sinensis 9-18 parts, Arillus Longan 6-12 parts, Radix Bupleuri 6-15 parts, Radix Paeoniae Alba 9-18 parts, Poria cum Radix Pini's 6-12 parts, Herba Lophatheri 6-12 parts, Semen Platycladi 6-12 parts, Radix Glycyrrhizae 6-15 parts.
2. the Chinese medicine composition that treatment according to claim 1 is had a sleepless night, it is characterised in that the Chinese medicine of the Chinese medicine composition Raw material and weight proportion are:
20 parts of Semen Ziziphi Spinosae, 15 parts of Radix Polygalae, 20 parts of Radix Codonopsis, 20 parts of the Radix Astragali, 15 parts of Radix Angelicae Sinensis, 9 parts of Arillus Longan, 9 parts of Radix Bupleuri, the Radix Paeoniae Alba 15 Part, 9 parts of Poria cum Radix Pini, 6 parts of Herba Lophatheri, 9 parts of Semen Platycladi, 9 parts of Radix Glycyrrhizae.
3. a kind of method for preparing Chinese medicine composition as claimed in claim 1, it is characterised in that comprise the steps:
Step one, raw material of Chinese medicine as claimed in claim 1 is weighed, be mixed in proportion, and mixed raw material of Chinese medicine is crushed Into granule;
Step 2, by the feed particles obtained by step one with ethanol soak, reflux, extract, 2 times, merge alcohol extract, raw material medicinal residues Standby;
Step 3, the raw material medicinal residues described in step 2 are boiled with decocting, decocted 2 times, merge decocting liquid;
Step 4, in the decocting liquid described in step 3,98% ethanol is added, which is heated and is concentrated into determining alcohol 70%, water is obtained Extract;
Step 5, the alcohol extract described in step 2 and the Aqueous extracts described in step 4 are merged into mixed liquor, mixed liquor is carried out Decompression is to reclaim alcohol solvent, and prepared by mixed liquor concentration fluid extract;
Step 6, the fluid extract obtained by step 5 is spray-dried, is obtained dry containing Chinese medicine composition effective ingredient Powder.
4. a kind of method for preparing Chinese medicine composition as claimed in claim 1, it is characterised in that comprise the steps:
Step one, raw material of Chinese medicine as claimed in claim 1 is weighed, be mixed in proportion, and mixed raw material of Chinese medicine is crushed Into granule;
Step 2, by the feed particles obtained by step one with ethanol soak, reflux, extract, 2 times, merge alcohol extract,
Step 3, the alcohol extract described in step 2 is reduced pressure to reclaim alcohol solvent, and alcohol extract concentration is prepared stream leaching Cream;
Step 4, the fluid extract obtained by step 3 is spray-dried, is obtained dry containing Chinese medicine composition effective ingredient Powder.
5. a kind of method for preparing Chinese medicine composition as claimed in claim 1, it is characterised in that comprise the steps:
Step one, raw material of Chinese medicine as claimed in claim 1 is weighed, be mixed in proportion, and mixed raw material of Chinese medicine is crushed Into granule;
Step 2, by the feed particles obtained by step one with water soak 1-2h;
Step 3, the immersion raw material in step 2 is boiled with decocting, decocted 2 times, merge decocting liquid;
Step 4, by obtained by step 3 decocting liquid heating concentration prepare fluid extract;
Step 5, the fluid extract obtained by step 4 is spray-dried, is obtained dry containing Chinese medicine composition effective ingredient Powder.
6. the method according to claim 3 or 4, it is characterised in that concentration of alcohol is 70-80% in the step 2, leaching The bubble time is 1.5-2.5h.
7. the method according to claim 3 or 5, it is characterised in that decoct 6-10 of the water yield for raw material in the step 3 Times, decocting time is 40-70min.
8. the method according to any one of claim 3-5, it is characterised in that the relative density of the fluid extract is 1.15-1.35(35℃).
9. application of a kind of Chinese medicine composition as claimed in claim 1 in medicament for treating insomnia is prepared.
10. a kind of Chinese medicine composition as claimed in claim 1 containing therapeutically effective amount is medicinal with pharmaceutically acceptable The preparation of adjuvant composition.
CN201611016851.0A 2016-11-18 2016-11-18 A kind of Chinese medicine composition for treating insomnia and preparation method thereof Pending CN106492018A (en)

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN107319222A (en) * 2017-08-23 2017-11-07 宁波甬鸿优尚餐饮有限公司 A kind of Anshen Bunao gynostemma pentaphylla Chinese herbal health-caring beverage and preparation method thereof
CN108743757A (en) * 2018-08-21 2018-11-06 刁静武 A kind of Chinese medicine composition and the preparation method and application thereof for treating insomnia
CN112471467A (en) * 2020-12-10 2021-03-12 广东生和堂健康食品股份有限公司 Tortoise jelly with sleep-aiding efficacy and preparation method thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107319222A (en) * 2017-08-23 2017-11-07 宁波甬鸿优尚餐饮有限公司 A kind of Anshen Bunao gynostemma pentaphylla Chinese herbal health-caring beverage and preparation method thereof
CN108743757A (en) * 2018-08-21 2018-11-06 刁静武 A kind of Chinese medicine composition and the preparation method and application thereof for treating insomnia
CN112471467A (en) * 2020-12-10 2021-03-12 广东生和堂健康食品股份有限公司 Tortoise jelly with sleep-aiding efficacy and preparation method thereof

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Application publication date: 20170315