CN106466340A - A kind of Herba indigoferae Pseudotinctoriae is aid digestion bath effervescent tablets and preparation method thereof - Google Patents
A kind of Herba indigoferae Pseudotinctoriae is aid digestion bath effervescent tablets and preparation method thereof Download PDFInfo
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- CN106466340A CN106466340A CN201510513370.XA CN201510513370A CN106466340A CN 106466340 A CN106466340 A CN 106466340A CN 201510513370 A CN201510513370 A CN 201510513370A CN 106466340 A CN106466340 A CN 106466340A
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Abstract
A kind of Herba indigoferae Pseudotinctoriae is aid digestion bath effervescent tablets and preparation method thereof, it is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Herba indigoferae Pseudotinctoriae 50-70 part, Radix Loti Corniculati 15-20 part, Radix Ardisiae Crispae 15-20 part, Pulvis Fumi Carbonisatuss 8-12 part, Herba Beesiae Calthaefoliae 8-12 part, Folium Perillae Frutescentiss 5-8 part, Caulis Perillae Frutescentiss 5-8 part, Flos micheliae Albae 5-8 part, Caulis et Folium Sinapis albee 5-8 part, Resina Liquidambariss 5-8 part, the mainly comprising the following steps of preparation method：Step 1, prepare Chinese medicine extract：Clean, remove impurity, mixing, extraction；Step 2, mixing：Prepare acid particles, prepare alkali grain, mixing, tabletting.A kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae of the present invention, life-time service has functions that aid digestion, qi-restoratives, heat clearing away.
Description
Technical field
The present invention relates to a kind of health body-wash articles for use, particularly a kind of Herba indigoferae Pseudotinctoriae is aid digestion bath effervescent tablets and preparation method thereof.
Background technology
In the traditional Chinese medical science, dipping method is one of external treatment, that is, use medicinal liquid or a kind of method containing medicinal liquid water washing bath whole body or local, and its form is varied：Have full bath and claim " liquid medicine bath "；The title again having " scalding ", " fumigation and wash method ", " demibain ", " foot bath " etc. of local bathing, especially scalds the most commonly used.
Chinese dipping, have existed since ancient times.Earliest hospital of China<52 Bingfang>In just have the dipping side controlling baby's epilepsy.《Book of Rites》In say " head has skin ulcer then to wash one's hair, and body has infectionss then to bathe ",《Huang di's Canon of Medicine》In have the record of " its be subject to exopathogen person, bathing the body with hot decoction to induce diaphoresis ", can say, the history of dipping is of long standing and well established, be laid a foundation in the Qin Dynasty, be developed in Chinese Tang, enrich in Song Ming, ripe in the Qing Dynasty.
The common dipping species in current market is broadly divided into three classes, including：Full bath, demibain, foot bath, using method is also very simply it is only necessary in the liquid medicine having dissolved to the bidet entering to mix up water temperature and the water yield or bath bucket, then steep body in water；Client progressively can experience the change of body generation during bathing.
The dipping mechanism of action in general, be medicine act on whole body flesh table, locally, affected part, and through absorb, circulation meridians blood vessels, inside reach internal organs, from outward appearance to inner essence, thus produce effect.Dipping bathing, can play dredging the meridian, activating blood circulation to dissipate blood stasis, wind dispelling cold expelling, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, regulating YIN and YANG, coordinate internal organs, current QI and blood, moisten the health maintenance effect such as foster whole body.Modern pharmacology also confirms that, can improve the content of some immunoglobulins in blood after dipping, strengthens elasticity and the vigor of skin.
Medicine used by dipping on market mostly is medicinal liquid or medicated powder, medicinal liquid or medicated powder is not portable, and composition easily runs off, and medicinal liquid that most of Chinese herbal medicine process or medicated powder cannot the sufficiently effective effective ingredient playing Chinese crude drug, loss or the waste of drug effect can be caused, and be prepared into effervescent tablet and be then easy to preserve and carry, dissolution velocity is fast, bioavailability is high, can improve clinical efficacy.
At present, digestant medicine or health product have much on market, but the effect of most drug is not very well, and the side effect of most drug is more, and health can be damaged, and therefore, market is badly in need of a kind of
Herba indigoferae Pseudotinctoriae is aid digestion bath effervescent tablets and preparation method thereof.
Content of the invention
It is an object of the invention to provide aid digestion bath effervescent tablets of a kind of Herba indigoferae Pseudotinctoriae and preparation method thereof, life-time service has aid digestion, qi-restoratives, the effect of heat clearing away.
The purpose of the present invention is achieved through the following technical solutions：
A kind of Herba indigoferae Pseudotinctoriae is aid digestion bath effervescent tablets and preparation method thereof, it is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Herba indigoferae Pseudotinctoriae 50-70 part, Radix Loti Corniculati 15-20 part, Radix Ardisiae Crispae 15-20 part, Pulvis Fumi Carbonisatuss 8-12 part, Herba Beesiae Calthaefoliae 8-12 part, Folium Perillae Frutescentiss 5-8 part, Caulis Perillae Frutescentiss 5-8 part, Flos micheliae Albae 5-8 part, Caulis et Folium Sinapis albee 5-8 part, Resina Liquidambariss 5-8 part.
In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Herba indigoferae Pseudotinctoriae, 18 parts of Radix Loti Corniculati, 17 parts of Radix Ardisiae Crispae, 12 parts of Pulvis Fumi Carbonisatuss, 10 parts of Herba Beesiae Calthaefoliae, 8 parts of Folium Perillae Frutescentiss, 7 parts of Caulis Perillae Frutescentiss, 6 parts of Flos micheliae Albae, 5 parts of Caulis et Folium Sinapis albee, 5 parts of Resina Liquidambariss.
Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
Described alkaline agent is sodium carbonate or sodium bicarbonate.
Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
Described binding agent is starch slurry or Microcrystalline Cellulose.
Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
Described aid digestion bath effervescent tablets of a kind of Herba indigoferae Pseudotinctoriae and preparation method thereof, the mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
a
, by weight, the Herba indigoferae Pseudotinctoriae of selection high-quality, Radix Loti Corniculati, Radix Ardisiae Crispae, Pulvis Fumi Carbonisatuss, Herba Beesiae Calthaefoliae, Folium Perillae Frutescentiss, Caulis Perillae Frutescentiss, Flos micheliae Albae, Caulis et Folium Sinapis albee, Resina Liquidambariss, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
b
, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
a
, the solid particle obtaining in step 1 is divided into uniform two parts, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
b
, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
c
, second part
Solid particle adds the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
d
, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae.
In medicine：Herba indigoferae Pseudotinctoriae controls scrofula, hemorrhoid, food stagnation, the cold cough of sense；Radix Loti Corniculati qi-restoratives；Heat clearing away；Quench the thirst；Main asthenia；Fever due to yin deficiency；Thirsty；Radix Ardisiae Crispae heat clearing away, eliminating the phlegm, dampness removing, control laryngopharynx swelling and pain, pneumonopathy is coughed, cough up phlegm not smooth, jaundice due to damp-heat, oedema due to nephritis, dysentery, nebulousurine, rheumatic ostalgia, toothache, painful and swollen testis；Pulvis Fumi Carbonisatuss stop blooding, and removing food stagnancy is controlled haematemesis, epistaxis, had blood in stool, metrorrhagia, leukorrhagia, dysentery, food stagnation, all skin ulcers of throat dispute；Herba Beesiae Calthaefoliae eases pain, dispersing wind and cold, dispelling the wind and dampness pathogens bones and muscles pain, waist and leg ache, dizzy and toothache；Folium Perillae Frutescentiss induce sweat, cold expelling, and qi-regulating helps digestion, and cure cold wind and cold, fever with aversion to cold, cough, asthma, and food stagnation is vomited and diarrhoea, cold-dysentery；Caulis Perillae Frutescentiss are pleasant to help digestion；Pain relieving；Antiabortive；Staple food is stagnant not to be changed；Abdominal distention；Flu；Frequent fetal movement；Flos micheliae Albae cough-relieving, changes turbid, controls chronic bronchitiss, prostatitis, women leucorrhea；Caulis et Folium Sinapis albee warming spleen and stomach for dispelling cold, controls cough out of breath, stomach, abdomen cold type of pain；Resina Liquidambariss are invigorated blood circulation, removing heat from blood, removing toxic substances, pain relieving, control carbuncle, sore scabies, urticaria, scrofula, incised wound, toothache, spit blood, epistaxis
.
Beneficial effects of the present invention：One kind of the present invention
Herba indigoferae Pseudotinctoriae is aid digestion bath effervescent tablets, to scrofula, hemorrhoid etc.
Main
Disease
Card serves to varying degrees
Aid digestion, qi-restoratives, heat clearing away
Effect,
There are health care, instant effect, pure natural, no side effectses.
The present invention uses the present invention through two groups of clinical verifications, one of which for treatment group, uses the present invention once daily, is within 7 days a course for the treatment of, and another group of matched group is taken
JIANWEI XIAOSHI PIAN in river
, daily using once, being within 7 days a course for the treatment of, every group selection outpatient 110, wherein man 55, female 55, max age 80 years old, minimal ages 35 years old, clinical manifestation is scrofula, hemorrhoid, food stagnation, the cold cough of sense, asthenia, fever due to yin deficiency
, table one is the contrasting data after taking a course for the treatment of：
Table 1 is taken two groups of courses for the treatment of of before and after and is compared (unit:People)
There were significant differences for treatment group and matched group, it will thus be seen that present invention application clinically has significant curative effect.
Specific embodiment
Embodiment 1
A kind of Herba indigoferae Pseudotinctoriae is aid digestion bath effervescent tablets and preparation method thereof, it is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Herba indigoferae Pseudotinctoriae 50-70 part, Radix Loti Corniculati 15-20 part, Radix Ardisiae Crispae 15-20 part, Pulvis Fumi Carbonisatuss 8-12 part, Herba Beesiae Calthaefoliae 8-12 part, Folium Perillae Frutescentiss 5-8 part, Caulis Perillae Frutescentiss 5-8 part, Flos micheliae Albae 5-8 part, Caulis et Folium Sinapis albee 5-8 part, Resina Liquidambariss 5-8 part.
In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Herba indigoferae Pseudotinctoriae, 18 parts of Radix Loti Corniculati, 17 parts of Radix Ardisiae Crispae, 12 parts of Pulvis Fumi Carbonisatuss, 10 parts of Herba Beesiae Calthaefoliae, 8 parts of Folium Perillae Frutescentiss, 7 parts of Caulis Perillae Frutescentiss, 6 parts of Flos micheliae Albae, 5 parts of Caulis et Folium Sinapis albee, 5 parts of Resina Liquidambariss.
Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
Described alkaline agent is sodium carbonate or sodium bicarbonate.
Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
Described binding agent is starch slurry or Microcrystalline Cellulose.
Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
Described aid digestion bath effervescent tablets of a kind of Herba indigoferae Pseudotinctoriae and preparation method thereof, the mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
a
, by weight, the Herba indigoferae Pseudotinctoriae of selection high-quality, Radix Loti Corniculati, Radix Ardisiae Crispae, Pulvis Fumi Carbonisatuss, Herba Beesiae Calthaefoliae, Folium Perillae Frutescentiss, Caulis Perillae Frutescentiss, Flos micheliae Albae, Caulis et Folium Sinapis albee, Resina Liquidambariss, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
b
, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
a
, the solid particle obtaining in step 1 is divided into uniform two parts, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
b
, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
c
, second part
Solid particle adds the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
d
, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae.
Claims (8)
1. a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae it is characterised in that：It is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Herba indigoferae Pseudotinctoriae 50-70 part, Radix Loti Corniculati 15-20 part, Radix Ardisiae Crispae 15-20 part, Pulvis Fumi Carbonisatuss 8-12 part, Herba Beesiae Calthaefoliae 8-12 part, Folium Perillae Frutescentiss 5-8 part, Caulis Perillae Frutescentiss 5-8 part, Flos micheliae Albae 5-8 part, Caulis et Folium Sinapis albee 5-8 part, Resina Liquidambariss 5-8 part.
2. a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae according to claim 1 it is characterised in that：In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Herba indigoferae Pseudotinctoriae, 18 parts of Radix Loti Corniculati, 17 parts of Radix Ardisiae Crispae, 12 parts of Pulvis Fumi Carbonisatuss, 10 parts of Herba Beesiae Calthaefoliae, 8 parts of Folium Perillae Frutescentiss, 7 parts of Caulis Perillae Frutescentiss, 6 parts of Flos micheliae Albae, 5 parts of Caulis et Folium Sinapis albee, 5 parts of Resina Liquidambariss.
3. a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae according to claim 1 it is characterised in that：Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
4. a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae according to claim 1 it is characterised in that：Described alkaline agent is sodium carbonate or sodium bicarbonate.
5. a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae according to claim 1 it is characterised in that：Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
6. a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae according to claim 1 it is characterised in that：Described binding agent is starch slurry or Microcrystalline Cellulose.
7. a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae according to claim 1 it is characterised in that：Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
8. aid digestion bath effervescent tablets of a kind of Herba indigoferae Pseudotinctoriae according to claim 1-7 and preparation method thereof it is characterised in that：The mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
A, by weight, the Herba indigoferae Pseudotinctoriae of selection high-quality, Radix Loti Corniculati, Radix Ardisiae Crispae, Pulvis Fumi Carbonisatuss, Herba Beesiae Calthaefoliae, Folium Perillae Frutescentiss, Caulis Perillae Frutescentiss, Flos micheliae Albae, Caulis et Folium Sinapis albee, Resina Liquidambariss, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
B, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
A, the solid particle obtaining in step 1 is divided into uniform two parts, chooses sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
B, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
C, second part of solid particle add the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
D, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of aid digestion bath effervescent tablets of Herba indigoferae Pseudotinctoriae.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107551187A (en) * | 2017-09-08 | 2018-01-09 | 常州市鼎日环保科技有限公司 | A kind of preparation method of aid digestion effervescent tablet |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107551187A (en) * | 2017-09-08 | 2018-01-09 | 常州市鼎日环保科技有限公司 | A kind of preparation method of aid digestion effervescent tablet |
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