CN105125702A - White poplar bark wind-dispelling bath effervescent tablet and preparing method of white poplar bark wind-dispelling bath effervescent tablet - Google Patents

White poplar bark wind-dispelling bath effervescent tablet and preparing method of white poplar bark wind-dispelling bath effervescent tablet Download PDF

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CN105125702A
CN105125702A CN201510509819.5A CN201510509819A CN105125702A CN 105125702 A CN105125702 A CN 105125702A CN 201510509819 A CN201510509819 A CN 201510509819A CN 105125702 A CN105125702 A CN 105125702A
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parts
wind
bath effervescent
cortex populi
dispelling
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尹海全
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Harbin Lingcaoshu Biotechnology Co Ltd
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Harbin Lingcaoshu Biotechnology Co Ltd
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Abstract

The invention relates to a white poplar bark wind-dispelling bath effervescent tablet and a preparing method of the white poplar bark wind-dispelling bath effervescent tablet. The white poplar bark wind-dispelling bath effervescent tablet is prepared from the following ingredients in percentage by weight: 20 to 35 percent of traditional Chinese medicine extracts, 10 to 20 percent of acid agents, 10 to 20 percent of alkaline agents, 30 to 50 percent of filling agents, 1 to 10 percent of bonding agents, 1 to 10 percent of lubricating agents and 0.1 to 1 percent of aromatic agents, wherein the traditional Chinese medicine extracts comprise the following ingredients in parts by weight: 50 to 70 parts of white poplar barks, 15 to 20 parts of hawksbills, 15 to 20 parts of radix puerariae, 8 to 12 parts of cornus officinalis, 8 to 12 parts of walnut kernels, 5 to 8 parts of chrysanthemums, 5 to 8 parts of pearls, 5 to 8 parts of cherokee rose fruits, 5 to 8 parts of ginseng and 5 to 8 parts of myrobalan. The preparing method comprises the following main steps of: 1, traditional Chinese medicine extract preparation: cleaning, impurity removal, mixing and extraction; and 2, mixing: acid particle preparation, alkaline particle preparation, mixing and tabletting. The white poplar bark wind-dispelling bath effervescent tablet has the effects of dispelling wind, removing stasis and dissolving phlegm after being used for a long time.

Description

A kind of Cortex Populi Davidianae dispels the wind bath effervescent tablets and preparation method thereof
Technical field
the present invention relates to a kind of health body-wash articles for use, particularly a kind of Cortex Populi Davidianae to dispel the wind bath effervescent tablets and preparation method thereof.
Background technology
in the traditional Chinese medical science, dipping method is one of external treatment, and namely by medicinal liquid or a kind of method containing medicinal liquid water washing bath whole body or local, its form is varied: have full bath and claim " liquid medicine bath "; The title having again " scalding ", " fumigation and wash method ", " demibain ", " foot bath " etc. of local bathing, especially scalds the most conventional.
china's dipping, have existed since ancient times.The dipping side controlling baby's epilepsy is just had in China hospital < 52 Bingfang > the earliest.Say in " Book of Rites " " head has skin ulcer then to wash one's hair, and body has infections then to bathe ", have the record of " it is by exopathogen person, bathing the body with hot decoction to induce diaphoresis " in Huangdi's Internal Classics, can say, the history of dipping is of long standing and well established, is laid a foundation in the Qin Dynasty, develops in Chinese Tang, enriches in Song Ming, ripe in the Qing Dynasty.
the common dipping kind in current market is mainly divided three classes, comprise: full bath, demibain, foot bath, using method also very simple, only needs the liquid medicine dissolved in the bidet entering to mix up water temperature and the water yield or bath bucket, then health is steeped in water; Client progressively can experience the change that health occurs in the process of bathing.
the dipping mechanism of action in general, be drug effect in whole body flesh table, locally, affected part, and through absorb, follow network blood vessels of passing through, inside reach internal organs, from outward appearance to inner essence, thus produce effect.Dipping bathing, can play dredging the meridian, activating blood circulation to dissipate blood stasis, wind dispelling cold expelling, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, regulating YIN and YANG, coordination internal organs, current QI and blood, moisten the health maintenance effect such as foster whole body.Modern pharmacology also confirms, can improve the content of some immunoglobulin in blood after dipping, strengthens elasticity and the vigor of skin.
the medicine that on market, dipping is used mostly is medicinal liquid or medicated powder, medicinal liquid or medicated powder are not portable, and composition easily runs off, and the medicinal liquid that most of Chinese herbal medicine processes or medicated powder fully effectively cannot play the effective ingredient of Chinese crude drug, loss or the waste of drug effect can be caused, be prepared into effervescent tablet to be then convenient to preserve and carry, dissolution velocity is fast, bioavailability is high, can improve clinical efficacy.
at present, the medicine dispeled the wind in market or health product have a lot, but the effect of most drug is not fine, and the side effect of most drug is more, can damage health, therefore, market is badly in need of a kind of Cortex Populi Davidianae and dispels the wind bath effervescent tablets and preparation method thereof.
Summary of the invention
the object of this invention is to provide a kind of Cortex Populi Davidianae to dispel the wind bath effervescent tablets and preparation method thereof, life-time service have dispel the wind, clots absorbing, expectorant effect.
object of the present invention is achieved through the following technical solutions:
a kind of Cortex Populi Davidianae dispels the wind bath effervescent tablets and preparation method thereof, be made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%; Described Chinese medicine extract Raw by weight, Cortex Populi Davidianae 50-70 part, Carapax Eretmochelydis 15-20 part, Radix Puerariae 15-20 part, Fructus Corni 8-12 part, Semen Juglandis 8-12 part, Flos Chrysanthemi 5-8 part, Margarita 5-8 part, Fructus Rosae Laevigatae 5-8 part, Radix Ginseng 5-8 part, Fructus Chebulae 5-8 part.
described Chinese medicine extract Raw presses optimum weight number, Cortex Populi Davidianae 60 parts, Carapax Eretmochelydis 18 parts, Radix Puerariae 17 parts, Fructus Corni 12 parts, Semen Juglandis 10 parts, Flos Chrysanthemi 8 parts, Margarita 7 parts, Fructus Rosae Laevigatae 6 parts, Radix Ginseng 5 parts, Fructus Chebulae 5 parts.
described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
described alkaline agent is sodium carbonate or sodium bicarbonate.
described filler is the mixing of microcrystalline Cellulose, sucrose, lactose, sodium chloride, calcium sulfate wherein one or more.
described binding agent is starch slurry or microcrystalline Cellulose.
described lubricant is one or both the mixing in magnesium stearate, sodium lauryl sulphate.
described a kind of Cortex Populi Davidianae dispels the wind bath effervescent tablets and preparation method thereof, and the key step of its preparation method is:
step 1, prepare Chinese medicine extract:
a, by weight, choose the Cortex Populi Davidianae of high-quality, Carapax Eretmochelydis, Radix Puerariae, Fructus Corni, Semen Juglandis, Flos Chrysanthemi, Margarita, Fructus Rosae Laevigatae, Radix Ginseng, Fructus Chebulae, clean and remove impurity, mix homogeneously after remove impurity, decoct with water three times, first time adds the little fire of 12-15 water doubly and decocts 90-120 minute, filters, extracts filtrate, second time adds 10-12 water moderate heat doubly and decocts 60-90 minute, filter, extract filtrate, third time adds 6-8 water big fire doubly and decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract;
b, mixed extract to be concentrated, use spray dryer dry after concentrated, obtain solids mixing extract, pulverized 60-80 mesh sieve, and obtained solid particle;
step 2, mixing:
a, divide uniformly two parts by the solid particle obtained in step 1, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves;
b, first part of solid particle add the sour agent after pulverizing, filler, binding agent, then trough type mixing machine is put into, open trough type mixing machine and mix 30 minutes, in trough type mixing machine, add the PVPK30 alcoholic solution that concentration is 1%, soft material processed, add to soft material moderate after, soft material is put into oscillating granulator, makes granule, 60 eye mesh screens on oscillating granulator, dry, obtain acid particles;
c, second part of solid particle add alkaline agent, filler, binding agent after pulverizing, then trough type mixing machine is put into, open trough type mixing machine and mix 30 minutes, in trough type mixing machine, add the PVPK30 alcoholic solution that concentration is 1%, soft material processed, add to soft material moderate after, soft material is put into oscillating granulator, makes granule, 60 eye mesh screens on oscillating granulator, dry, obtain alkali grain;
d, by acid particles, alkali grain, lubricant, aromatic mixing, fully put into automatic tableting press tabletting after mixing, aluminum-plastic packaged, obtain a kind of Cortex Populi Davidianae and to dispel the wind bath effervescent tablets.
in medicine: Cortex Populi Davidianae dispels the wind, clots absorbing, expectorant, controls migratory arthralgia, beriberi, flutters damage blood stasis, pregnant dysentery, toothache, aphtha; Carapax Eretmochelydis heat-clearing and toxic substances removing, relieving palpitation suppressing the hyperactive liver, goes mad for calentura, delirium, infantile convulsion, carbuncle sore tumefacting virus; Radix Puerariae yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness is temperature only, and cure the wound cold, warm headache, and dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, dysentery, and skin eruption is not saturating, hypertension, and angina pectoris is deaf; Fructus Corni liver and kidney tonifying, arresting seminal emission hidroschesis, has a dizzy spell, deaf, spontaneous perspiration, soreness of the waist and knees, and sexual impotence, sends essence, frequent micturition; Semen Juglandis temperature compensation lung kidney, Dingchuan intestine moistening; For lumbago due to renal deficiency, foot is soft, deficiency and coldness is breathed with cough, constipation due to dry stool; The heat clearing away of chrysanthemum powder forimproving wind, suppressing the hyperactive liver improving eyesight; For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted; Margarita is calmed the nerves arresting convulsion, improving eyesight removing nebula, removing toxic substances and promoting granulation; For insomnia of palpitating with fear, infantile convulsion epilepsy, the raw nebula of order, skin infection is not held back; Fructus Rosae Laevigatae controlling nocturnal emission with astringent drugs reducing urination, relieving diarrhea with astringents; For emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses, chronic diarrhea chronic dysentery; Ginseng qi-tonifying, Gu de-, promote the production of body fluid, calms the nerves, Fructus Alpiniae Oxyphyllae; For dyspnea with shortness of breath, palpitation and amnesia, thirsty hyperhidrosis, lack of appetite is unable, all acute and chronic diseases and the shock caused after losing blood, collapse; Fructus Chebulae astringes the lung; Astringing intestine to stop diarrhea; The therapeutic method to keep the adverse QI flowing downwards; Sore-throat relieving; Main chronic diarrhea; Chronic dysentery; Proctoptosis; To breath with cough phlegmatic cough; Chronic cough aphonia.
beneficial effect of the present invention: a kind of Cortex Populi Davidianae of the present invention dispels the wind bath effervescent tablets, to migratory arthralgia, the main disease such as beriberi serve in varying degrees dispel the wind, clots absorbing, expectorant effect, there is the advantages such as health care, instant effect, pure natural, no side effects.
the present invention is through two groups of clinical verifications, and wherein one group is that treatment group uses the present invention, uses the present invention every day once, within 7 days, is a course for the treatment of, another group matched group is taken Rhizoma Gastrodiae and to be dispeled the wind soup stock, and taking every day once, 7 days is a course for the treatment of, every group selection outpatient 110 example, wherein man 55 example, female 55 example, max age 75 years old, minimal ages 31 years old, clinical manifestation is migratory arthralgia, beriberi, flutters damage blood stasis, pregnant dysentery, toothache, aphtha, table 1 is for taking the contrasting data after the course for the treatment of:
table 1 is taken front and back and is compared (unit: people) two groups of courses for the treatment of
there were significant differences for treatment group and matched group, thus can find out that the present invention's application clinically has significant curative effect.
Detailed description of the invention
embodiment 1
a kind of Cortex Populi Davidianae dispels the wind bath effervescent tablets and preparation method thereof, be made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%; Described Chinese medicine extract Raw by weight, Cortex Populi Davidianae 50-70 part, Carapax Eretmochelydis 15-20 part, Radix Puerariae 15-20 part, Fructus Corni 8-12 part, Semen Juglandis 8-12 part, Flos Chrysanthemi 5-8 part, Margarita 5-8 part, Fructus Rosae Laevigatae 5-8 part, Radix Ginseng 5-8 part, Fructus Chebulae 5-8 part.
described Chinese medicine extract Raw presses optimum weight number, Cortex Populi Davidianae 60 parts, Carapax Eretmochelydis 18 parts, Radix Puerariae 17 parts, Fructus Corni 12 parts, Semen Juglandis 10 parts, Flos Chrysanthemi 8 parts, Margarita 7 parts, Fructus Rosae Laevigatae 6 parts, Radix Ginseng 5 parts, Fructus Chebulae 5 parts.
described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
described alkaline agent is sodium carbonate or sodium bicarbonate.
described filler is the mixing of microcrystalline Cellulose, sucrose, lactose, sodium chloride, calcium sulfate wherein one or more.
described binding agent is starch slurry or microcrystalline Cellulose.
described lubricant is one or both the mixing in magnesium stearate, sodium lauryl sulphate.
described a kind of Cortex Populi Davidianae dispels the wind bath effervescent tablets and preparation method thereof, and the key step of its preparation method is:
step 1, prepare Chinese medicine extract:
a, by weight, choose the Cortex Populi Davidianae of high-quality, Carapax Eretmochelydis, Radix Puerariae, Fructus Corni, Semen Juglandis, Flos Chrysanthemi, Margarita, Fructus Rosae Laevigatae, Radix Ginseng, Fructus Chebulae, clean and remove impurity, mix homogeneously after remove impurity, decoct with water three times, first time adds the little fire of 12-15 water doubly and decocts 90-120 minute, filters, extracts filtrate, second time adds 10-12 water moderate heat doubly and decocts 60-90 minute, filter, extract filtrate, third time adds 6-8 water big fire doubly and decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract;
b, mixed extract to be concentrated, use spray dryer dry after concentrated, obtain solids mixing extract, pulverized 60-80 mesh sieve, and obtained solid particle;
step 2, mixing:
a, divide uniformly two parts by the solid particle obtained in step 1, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves;
b, first part of solid particle add the sour agent after pulverizing, filler, binding agent, then trough type mixing machine is put into, open trough type mixing machine and mix 30 minutes, in trough type mixing machine, add the PVPK30 alcoholic solution that concentration is 1%, soft material processed, add to soft material moderate after, soft material is put into oscillating granulator, makes granule, 60 eye mesh screens on oscillating granulator, dry, obtain acid particles;
c, second part of solid particle add alkaline agent, filler, binding agent after pulverizing, then trough type mixing machine is put into, open trough type mixing machine and mix 30 minutes, in trough type mixing machine, add the PVPK30 alcoholic solution that concentration is 1%, soft material processed, add to soft material moderate after, soft material is put into oscillating granulator, makes granule, 60 eye mesh screens on oscillating granulator, dry, obtain alkali grain;
d, by acid particles, alkali grain, lubricant, aromatic mixing, fully put into automatic tableting press tabletting after mixing, aluminum-plastic packaged, obtain a kind of Cortex Populi Davidianae and to dispel the wind bath effervescent tablets.

Claims (8)

1. a Cortex Populi Davidianae dispels the wind bath effervescent tablets, it is characterized in that: be made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%; Described Chinese medicine extract Raw by weight, Cortex Populi Davidianae 50-70 part, Carapax Eretmochelydis 15-20 part, Radix Puerariae 15-20 part, Fructus Corni 8-12 part, Semen Juglandis 8-12 part, Flos Chrysanthemi 5-8 part, Margarita 5-8 part, Fructus Rosae Laevigatae 5-8 part, Radix Ginseng 5-8 part, Fructus Chebulae 5-8 part.
2. a kind of Cortex Populi Davidianae according to claim 1 dispels the wind bath effervescent tablets, it is characterized in that: described Chinese medicine extract Raw by optimum weight number, Cortex Populi Davidianae 60 parts, Carapax Eretmochelydis 18 parts, Radix Puerariae 17 parts, Fructus Corni 12 parts, Semen Juglandis 10 parts, Flos Chrysanthemi 8 parts, Margarita 7 parts, Fructus Rosae Laevigatae 6 parts, Radix Ginseng 5 parts, Fructus Chebulae 5 parts.
3. a kind of Cortex Populi Davidianae according to claim 1 dispels the wind bath effervescent tablets, it is characterized in that: described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
4. a kind of Cortex Populi Davidianae according to claim 1 dispels the wind bath effervescent tablets, it is characterized in that: described alkaline agent is sodium carbonate or sodium bicarbonate.
5. a kind of Cortex Populi Davidianae according to claim 1 dispels the wind bath effervescent tablets, it is characterized in that: described filler is the mixing of microcrystalline Cellulose, sucrose, lactose, sodium chloride, calcium sulfate wherein one or more.
6. a kind of Cortex Populi Davidianae according to claim 1 dispels the wind bath effervescent tablets, it is characterized in that: described binding agent is starch slurry or microcrystalline Cellulose.
7. a kind of Cortex Populi Davidianae according to claim 1 dispels the wind bath effervescent tablets, it is characterized in that: described lubricant is one or both the mixing in magnesium stearate, sodium lauryl sulphate.
8. a kind of Cortex Populi Davidianae according to claim 1-7 dispels the wind bath effervescent tablets and preparation method thereof, it is characterized in that: the key step of its preparation method is:
Step 1, prepare Chinese medicine extract:
A, by weight, choose the Cortex Populi Davidianae of high-quality, Carapax Eretmochelydis, Radix Puerariae, Fructus Corni, Semen Juglandis, Flos Chrysanthemi, Margarita, Fructus Rosae Laevigatae, Radix Ginseng, Fructus Chebulae, clean and remove impurity, mix homogeneously after remove impurity, decoct with water three times, first time adds the little fire of 12-15 water doubly and decocts 90-120 minute, filters, extracts filtrate, second time adds 10-12 water moderate heat doubly and decocts 60-90 minute, filter, extract filtrate, third time adds 6-8 water big fire doubly and decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract;
B, mixed extract to be concentrated, use spray dryer dry after concentrated, obtain solids mixing extract, pulverized 60-80 mesh sieve, and obtained solid particle;
Step 2, mixing:
A, divide uniformly two parts by the solid particle obtained in step 1, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves;
B, first part of solid particle add the sour agent after pulverizing, filler, binding agent, then trough type mixing machine is put into, open trough type mixing machine and mix 30 minutes, in trough type mixing machine, add the PVPK30 alcoholic solution that concentration is 1%, soft material processed, add to soft material moderate after, soft material is put into oscillating granulator, makes granule, 60 eye mesh screens on oscillating granulator, dry, obtain acid particles;
C, second part of solid particle add alkaline agent, filler, binding agent after pulverizing, then trough type mixing machine is put into, open trough type mixing machine and mix 30 minutes, in trough type mixing machine, add the PVPK30 alcoholic solution that concentration is 1%, soft material processed, add to soft material moderate after, soft material is put into oscillating granulator, makes granule, 60 eye mesh screens on oscillating granulator, dry, obtain alkali grain;
D, by acid particles, alkali grain, lubricant, aromatic mixing, fully put into automatic tableting press tabletting after mixing, aluminum-plastic packaged, obtain a kind of Cortex Populi Davidianae and to dispel the wind bath effervescent tablets.
CN201510509819.5A 2015-08-19 2015-08-19 White poplar bark wind-dispelling bath effervescent tablet and preparing method of white poplar bark wind-dispelling bath effervescent tablet Withdrawn CN105125702A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105782738A (en) * 2016-04-27 2016-07-20 句容市万福达工艺品厂 Deodorization led lamp
CN106309401A (en) * 2016-10-14 2017-01-11 杭州惠博士生物科技有限公司 Bathing effervescent tablets for preventing and treating skin diseases
CN108186372A (en) * 2017-12-29 2018-06-22 青岛百瑞吉生物工程有限公司 A kind of whitening and skin-protecting bathing effervescent tablet and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101961409A (en) * 2010-09-14 2011-02-02 广东养美医药投资有限公司 Bathing effervescent tablets for improving qi deficiency and blood stasis type chest numbness

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101961409A (en) * 2010-09-14 2011-02-02 广东养美医药投资有限公司 Bathing effervescent tablets for improving qi deficiency and blood stasis type chest numbness

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105782738A (en) * 2016-04-27 2016-07-20 句容市万福达工艺品厂 Deodorization led lamp
CN106309401A (en) * 2016-10-14 2017-01-11 杭州惠博士生物科技有限公司 Bathing effervescent tablets for preventing and treating skin diseases
CN108186372A (en) * 2017-12-29 2018-06-22 青岛百瑞吉生物工程有限公司 A kind of whitening and skin-protecting bathing effervescent tablet and preparation method thereof

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Application publication date: 20151209