CN106266706B - It is a kind of to treat Chinese medicine composition of diabetes and preparation method thereof - Google Patents
It is a kind of to treat Chinese medicine composition of diabetes and preparation method thereof Download PDFInfo
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Abstract
The invention provides a kind of Chinese medicine composition for treating diabetes, the Chinese medicine being made up of following parts by weight is made：Ramulus euonymi 10 30, stevia rebaudian leaf 5 20, snake lotus 2 15, corn stigma 10 30, balsam pear 10 30, potentilla discolor 10 30, Chinese lizardtail rhizome 5 20 is made.The Chinese medicine composition of the present invention has effects that promoting blood circulation and removing blood stasis, nourishing Yin and clearing heat, Li Shui dehumidifying, reducing blood lipid, and so as to be obviously improved or alleviate the symptom of diabetes, and evident in efficacy, toxic and side effect is small, and preparation method raw material is easy to get, step is simple, reproducible.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for treating diabetes and its preparation side
Method.
Background technology
Diabetes are a kind of common endocrine metabolism diseases.Its basic pathology feature be insulin secretion definitely or phase
To deficiency, or peripheral tissues are to insulin insensitivity, cause based on carbohydrate metabolism disturbance, including fat, protein metabolism disorder
A kind of systemic disease.It is mainly characterized in that lasting hyperglycemia state, the glucose in urine positive and Impaired Glucose Tolerance Treated.The master of diabetes
Be characterized in many drink, diuresis, eat and become thin more, tired, urine it is sweet, the category of " quenching one's thirst " should be belonged in traditional Chinese medicine." disappearing " with
" thirsty " the two be the traditional Chinese medical science disease title, and the title of diabete, then head, which sees the Tang Dynasty doctor and discriminated, expounds one's ideas in writing《Proved recipe is recorded at all times》.
According to the difference of sick position, the cause of disease, the interpretation of the cause, onset and process of an illness and clinical symptom, thirst and drinking is above to disappear；Bulimia disappears in being；Drink one overflows one
Under disappear.
With the fast development of Chinese society economy, people's living standard is improved constantly, China's diabetic
Quantity is also drastically increasing with surprising rapidity.According to 20~74 years old population epidemiology sample survey results of national 11 province in 1996
Display：Diabetes prevalence is 4.8 times in 1980, reaches 3.21%.Impaired glucose tolerance (IGT) illness rate is 4.76%, than
0.8% in 1980 increases nearly 5 times.Meanwhile, China's diabetes increasing degree shows the distinguishing feature that rural area is more than city.
Estimate that there is diabetic in current China up to more than 3,000 ten thousand people, mainly diabetes B.IGT person nearly 6,000 ten thousand, wherein having 60%
~70% people is the diabetes patient for not obtaining diagnosis, and both amount to number and reach nearly 100,000,000.China turns into the generation for being only second to India
Second largest diabetes big country of boundary.Diabetes B illness rate is up to 11.34%, IGT up to 11.62% in crowd more than 60 years old.
In the crowd of 65 years old to 74 years old, diabetes patient and IGT person, which add up, can account for the 40% of the age bracket total number of persons, it is predicted that 2025
Year diabetes mellitus in China number will be up to 50,000,000.Being widely current for diabetes, increasingly becomes serious social hygiene's problem.
Traditional Chinese medicine long history in terms of the prevention and treatment of diabetes, the traditional Chinese medical science thinks, " accumulation of pathogen in YANG MING resulting in diabetes ", it is believed that
Gastrointestine dryness heat, causes the main pathogenesis that body fluid loss is the morbidity of diabetes.For the scorching basic pathogenesis of the deficiency of Yin, traditional Chinese medical science successive dynasties doctor
Family is constantly explored to it, and summarizing its therapy should be with nourishing Yin and clearing heat master.In addition, promoting blood circulationization is applied in also many researchs
The stasis of blood, kidney tonifying, qi-restoratives rush down the treatment diabetes such as real, achieve good result.Not only adverse reaction is small for TCM treatment of diabetes, and
And immunity of organisms can also be strengthened, improve diabetic symptom.
The content of the invention
In order to solve the present situation that diabetic increasingly increases, reduce because of the pain that diabetic symptom is brought, the present invention is carried
A kind of Chinese medicine composition for treating diabetes is supplied, the Chinese medicine composition has promoting blood circulation and removing blood stasis, nourishing Yin and clearing heat, Li Shui dehumidifying, drop
Effect of blood fat, can obviously improve or alleviate the symptom of diabetes, and evident in efficacy, toxic and side effect is small.In addition, Chinese medicine of the present invention
The preparation method raw material of composition is easy to get, step is simple, reproducible.
The purpose of the present invention is realized by following technical scheme.
First, it is by Ramulus euonymi, stevia rebaudian leaf, She Lian, jade the invention provides a kind of Chinese medicine composition for treating diabetes
Rice palpus, balsam pear, potentilla discolor, Chinese lizardtail rhizome is made.Under normal circumstances, Chinese medicine material can be directly ground to end and be taken after well mixed
With.But, various formulations will be made after the extracts active ingredients of Chinese medicine, it is easier to be accepted by patients, so as to improve patient's medication
Compliance, and therapeutic effect is also more preferably.Therefore, for the Chinese medicine composition of the present invention, Ramulus euonymi, stevia rebaudianum are preferably comprised
Leaf, She Lian, corn stigma, balsam pear, potentilla discolor, the decocting liquid of Chinese lizardtail rhizome.
As a preferred embodiment, the Chinese medicine system that Chinese medicine composition of the invention is made up of following parts by weight
Into：Ramulus euonymi 10-30, stevia rebaudian leaf 5-20, snake lotus 2-15, corn stigma 10-30, balsam pear 10-30, potentilla discolor 10-30, Chinese lizardtail rhizome
5-20 is made.
It is highly preferred that the Chinese medicine that the Chinese medicine composition of the present invention is made up of following parts by weight is made：Ramulus euonymi 12-18 is sweet
Chrysanthemum leaf 8-15, snake lotus 3-10, corn stigma 12-18, balsam pear 12-18, potentilla discolor 12-18, Chinese lizardtail rhizome 8-15 are made.
Most preferably, the Chinese medicine that Chinese medicine composition of the invention is made up of following parts by weight is made：Ramulus euonymi 15, stevia rebaudian leaf
10, snake lotus 6, corn stigma 15, balsam pear 15, potentilla discolor 15, Chinese lizardtail rhizome 10 is made.
In the pharmaceutical composition of the present invention, used Chinese medicine material is the common natural drug in this area.In each
The source of medicine and effect are as follows.
Ramulus euonymi：For the branch or aliform adjunct of the tool fin of Celastraceae plant winged euonymus.Property it is bitter, tremble with fear.Enter sufficient the moon of fainting
Through.With blood-breaking, stimulate the menstrual flow, effect of desinsection.For treating Amenorrhea, abdominal mass, postpartum stasis of blood, abdominal pain due to enterositosis.Ye Hanbiao without
Bridle terpene alcohol, freidelin, Quercetin, dulcitol.Containing saturated fatty acid (20%), oleic acid, linoleic acid, leukotrienes, in seed oil
Acid, acetic acid and benzoic acid etc., with hypoglycemic effect.
Stevia rebaudian leaf：For the leaf of feverfew STEVIA REBAUDIANA.It is sweet；Bosom is flat.With promoting the production of body fluid to quench thirst；Blood pressure reduction effect.Master quenches one's thirst；
High blood pressure.Stevia rebaudianum leaf composition Stevia rebaudiana acid waits the synthesis for suppressing sugar in renal cortex of rats tubule and the absorption of oxygen.
She Lian：Alias adder-wort, chicken feet king, hornet seven, Angiospermae, Latin literary fame：Hemsleya
Sphaerocarpa Kuang et A.M.Lu, are Curcurbitaceae Genus Hemsleya herbaceous species plant.Property puckery slight bitter, put down, it is nontoxic.Have
Heat-clearing, detoxifies, convergence, effect of myogenic.For treat stomach damp and hot, dysentery characterized by blood in the stool, aphthous stomatitis, carbuncle swells, hemorrhoid, burn.
Corn stigma：For grass family Zea plant Zea mays Zea mays L. style and fresh idea.Property it is sweet, light, put down.Return
Bladder, liver, gallbladder channel.With inducing diuresis to remove edema, effect of soothing the liver cholagogic.For acute and chronic ephritis, oedema, acute hepatitis, chronic hepatitis is high
Blood pressure, diabetes, chronic nasosinusitis, lithangiuria, Biliary Calculi, the disease such as difficult urination, neonatal jaundice caused by dampness-heat.And habituation can be prevented
Miscarriage.
Balsam pear：For Curcurbitaceae balsam pear platymiscium.Property melon, root, leaf：Hardship, it is cool.With clearing heat and detoxicating effect.For heatstroke
Heating, toothache, enteritis, dysentery is had blood in stool；Prickly heat, furunculosis furuncle are controlled in external application.
Potentilla discolor：For rose family potentilla plants potentilla discolor Potentilla discolor Bunge with herb or
Root.Property sweet, slight bitter, put down.Root contains tannin and flavonoids.With clearing heat and detoxicating, effect of cooling blood and hemostasis.It is bacillary for enteritis
Dysentery, amoebic dysentery is spitted blood, and bleeding from five sense organs or subcutaneous tissue is had blood in stool, leukorrhea；Wound, carbuncle furuncle poison are controlled in external application.
Chinese lizardtail rhizome：For the rhizome of Saururaceae plant saururus chinensis.Property it is sweet pungent, tremble with fear.Root contains amino acid, organic acid, carbohydrate,
And condensed tannin (0.48%).With Li Shui dehumidifying, clearing heat and detoxicating effect.Cure mainly tinea pedis shin to swell, stranguria with turbid discharge, under band, carbuncle
It is swollen, mange.
In the Chinese medicine preparation of the present invention, Ramulus euonymi has promoting blood circulation blood sugar reducing function, She Lian, balsam pear, potentilla discolor and saururus chinensis
The effect of root has clearing heat and detoxicating, stevia rebaudian leaf, corn stigma have effects that enriching yin step-down, soothing the liver cholagogic, and these medicines are carried out
Scientific and reasonable compatibility, can play a part of mutually cooperateing with, and promoting blood circulation and removing blood stasis, nourishing Yin and clearing heat, Li Shui dehumidifying, the work(of reducing blood lipid are played altogether
Effect, so as to be obviously improved or alleviate the symptom of diabetes, and evident in efficacy, toxic and side effect is small.
For the Chinese medicine composition of the present invention, the conventional form of Chinese drug in this area, example can be made after active component is extracted
Such as pill, tablet, capsule, pill, powder, granule, oral liquid.
Secondly there is provided the method for preparing pharmaceutical composition of the present invention, this method comprises the following steps：
(1) Ramulus euonymi, is weighed, stevia rebaudian leaf, She Lian, corn stigma, balsam pear, potentilla discolor, Chinese lizardtail rhizome dry, pulverize into thin
End；
(2), the decocting of 6-10 times of volume is added to boil twice the smalls of step (1), first time 2-5 hour, second of 0.5-2
Hour, collecting decoction；
(3), the decocting liquid of step (2) is filtered, it is the clear of 1.02-1.15 (60 DEG C) that filtrate decompression, which is concentrated into relative density,
Cream, then crosses the filtration of 200-400 mesh sieves while hot, and filtrate is spray-dried, and produces spray powder.
The active ingredient higher in order to obtain concentration, preferred steps (2) is add the decocting of 6-8 times of volume to boil twice, and first
It is secondary 2-3.5 hours, second 1-2 hours, collecting decoction；The spray drying condition of step (3) is：70-100 DEG C of outlet temperature,
130-160 DEG C of inlet temperature, flow velocity 8-12%, 25-30 DEG C of feed temperature.
The spray powder that the step of for above-mentioned preparation method (3) is obtained, preferably crosses 20-40 mesh sieves, then optionally adds
Enter pharmaceutically acceptable auxiliary material, pill, tablet, capsule, pill, powder, granule, oral liquid is made.
Finally, purposes of the Chinese medicine composition of the present invention in the medicine for preparing treatment diabetes is additionally provided.
Compared with prior art, it is of the invention to include following advantage：
(1), the present invention is on study of pathogenesis basis of motherland's traditional Chinese medicine for diabetes, by Ramulus euonymi, stevia rebaudian leaf,
She Lian, corn stigma, balsam pear, potentilla discolor, Chinese lizardtail rhizome carries out scientific and reasonable compatibility, can play a part of mutually cooperateing with, play altogether
Promoting blood circulation and removing blood stasis, nourishing Yin and clearing heat, effect of Li Shui dehumidifying, so as to be obviously improved or alleviate the symptom of diabetes, and evident in efficacy,
Toxic and side effect is small；
(2), Chinese medicine composition of the invention is after water boiling and extraction, and active constituent content is higher, and can further make
The standby form for being easier to receive into patients such as pill, tablet, capsule, pill, powder, granule, oral liquids, so that patient
Drug compliance it is more preferable；
(3), for preparing, the method raw material of Chinese medicine preparation of the present invention is easy to get, step is simple, reproducible, meets industry
The need for production.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, below in conjunction with tool of the embodiment to the present invention
Body embodiment is clearly and completely described.
Embodiment 1：
Formula and parts by weight composition：Ramulus euonymi 15, stevia rebaudian leaf 10, snake lotus 6, corn stigma 15, balsam pear 15, potentilla discolor 15, three
Root of Pennisetum centrasiaticum Tzvel 10.
Preparation method：Ramulus euonymi is weighed, stevia rebaudian leaf, She Lian, corn stigma, balsam pear, potentilla discolor, Chinese lizardtail rhizome dry, pulverize
Into smalls；The decocting of smalls plus 8 times of volumes is boiled twice, 3 hours for the first time, second 1 hour, collecting decoction；Decocting liquid is filtered
Cross, filtrate decompression is concentrated into the clear cream that relative density is 1.05 (60 DEG C), the filtration of 400 mesh sieves is then crossed while hot, filtrate is sprayed
Mist is dried, and produces spray powder, spray drying condition is：80 DEG C of outlet temperature, 140 DEG C of inlet temperature, flow velocity 10%, feed temperature
30℃；Spray powder crosses 40 mesh sieves, adds appropriate cornstarch and talcum powder, is well mixed, and fills to capsule shells, produces capsule
Agent.
Embodiment 2：
Formula and parts by weight composition：Ramulus euonymi 12, stevia rebaudian leaf 10, snake lotus 4, corn stigma 12, balsam pear 12, potentilla discolor 12, three
Root of Pennisetum centrasiaticum Tzvel 10.
Preparation method：Ramulus euonymi is weighed, stevia rebaudian leaf, She Lian, corn stigma, balsam pear, potentilla discolor, Chinese lizardtail rhizome dry, pulverize
Into smalls；The decocting of smalls plus 6 times of volumes is boiled twice, 2 hours for the first time, second 2 hours, collecting decoction；Decocting liquid is filtered
Cross, filtrate decompression is concentrated into the clear cream that relative density is 1.02 (60 DEG C), the filtration of 300 mesh sieves is then crossed while hot, filtrate is sprayed
Mist is dried, and produces spray powder, spray drying condition is：90 DEG C of outlet temperature, 150 DEG C of inlet temperature, flow velocity 8%, feed temperature
25℃；Spray powder crosses 20 mesh sieves, adds appropriate lactose, starch and magnesium stearate, is well mixed, direct tablet compressing produces tablet.
Embodiment 3：
Formula and parts by weight composition：Ramulus euonymi 17, stevia rebaudian leaf 9, snake lotus 5, corn stigma 17, balsam pear 17, potentilla discolor 17, three is white
Grass roots 8.
Preparation method：Ramulus euonymi is weighed, stevia rebaudian leaf, She Lian, corn stigma, balsam pear, potentilla discolor, Chinese lizardtail rhizome dry, pulverize
Into smalls；The decocting of smalls plus 10 times of volumes is boiled twice, 4 hours for the first time, second 1 hour, collecting decoction；Decocting liquid is filtered
Cross, filtrate decompression is concentrated into the clear cream that relative density is 1.12 (60 DEG C), the filtration of 200 mesh sieves is then crossed while hot, filtrate is sprayed
Mist is dried, and produces spray powder, spray drying condition is：70 DEG C of outlet temperature, 130 DEG C of inlet temperature, flow velocity 12%, feed temperature
28℃；Spray powder crosses 20 mesh sieves, adds appropriate maltodextrin, starch and honey, and pill is made after being well mixed.
Test example 1：Animal model therapeutic effect
1st, experimental animal
Healthy mice totally 50, male and female half and half, weight range is 20-28g.It is randomly divided into three groups, wherein normal group 10
Only, model group 20, treatment group 20.
2nd, animal test method
Mouse is weighed, model group and treatment group are injected with alloxan abdominal cavity, and dosage is 220mg/kg body weight, and 48 is small
Shi Hou, determines 6 hours blood glucoses on an empty stomach, and fasting blood-glucose >=8.0mmol/L is to model successfully.Treatment group's glue of the embodiment of the present application 1
Intracapsular tolerant aqueous dispersions treatment, every gavage 0.4ml, once a day, and continuous 7 days, model group equivalent distilled water gavage,
Determine before and after modeling, test the fasting blood-glucose terminated.Experiment end takes eyeball blood to centrifuge, and separates serum, determines T-CHOL, sweet
The concentration of oily three fat, urea and total protein.
3rd, result of the test
(1), change of blood sugar
Change of blood sugar result (P before and after each group mouse test of table 1<0.01)
As can be seen from Table 1, the blood glucose of model group and treatment group mouse is significantly raised after modeling, with the embodiment of the present application
After 1 traditional Chinese medicine composition for treating, the mouse blood sugar for the treatment of group is decreased obviously.
(2), changes of weight
Body weight result of variations (P before and after each group mouse test of table 2<0.01)
| Group | Quantity (only) | Before experiment (g) | After experiment (g) |
| Normal group | 10 | 25.49±1.58 | 25.72±0.85 |
| Model group | 20 | 26.84±1.26 | 21.36±1.23 |
| Treatment group | 20 | 26.05±1.54 | 22.64±1.85 |
As can be seen from Table 2, the body weight of normal group mouse does not have a significant change after off-test, but model group and controls
Body weight substantially mitigates the mouse for the treatment of group after experiment, because a large amount of blood glucose in diabetic mice body are arranged from urine
Walk, body consumes a large amount of protein to provide enough energy demands or fat causes and become thin.But, compared with model group, control
The Mouse Weight for the treatment of group mitigates less.
(3), serum composition changes of contents
Serum composition changes of contents result (P before and after each group mouse test of table 3<0.01)
The total protein content of model group and treatment group is below normal group before being tested it can be seen from the result of table 3, but passes through
Cross after treatment, the total protein content for the treatment of group illustrates that medicine promotes the synthesis of machine vivo protein apparently higher than model group.Generally
Diabetes can be raised with cholesterol and triglycerides isoconcentration, but compared with model group, treatment group's cholesterol after experiment
Significantly reduced with the content of triglycerides, illustrating the Chinese medicine composition of the present invention also has certain effect for reducing fat.In addition, and mould
Type group is compared, and treatment group's urea content after experiment is substantially reduced, and shows the Chinese medicine composition of the present invention and has certain to kidney
Protective effect.
4th, conclusion
Above-mentioned result of the test shows that Chinese medicine composition of the invention can not only reduce blood-sugar content, moreover it is possible to alleviate because of sugared generation
Thank to abnormal caused body to become thin rapidly, in addition, the Chinese medicine composition of the present invention can also reduce the total cholesterol of serum and sweet
Oily three ester contents, and advantageously increase the content of total protein, sugar can be relieved by thus proving the Chinese medicine composition of the present invention
The symptom of disease is urinated, there is significant therapeutic effect for diabetic.
Test example 2：Model case
Model case 1：Chen, man, 39 years old.Nearly hyperposia daily over the past half year, lean body mass substantially, usually feels easy
Fatigue, measures fasting blood-glucose 13.2mmol/l, and two hours blood glucoses are 19.5mmol/l after meal, and dose a patient with the embodiment of the present invention
1 Chinese medicine capsules, two months are a course for the treatment of twice daily.It is recommended that daily normal work and rest, and it is aided with appropriate exercise.Take
After one course for the treatment of, the tired sense of body disappears, and energy recovers normal, surveys its fasting blood-glucose 6.3mmol/l, 2 hours blood glucoses are after meal
8.6mmol/l。
Model case 2：Yao, man, 32 years old.It is type ii diabetes, glucose in urine (++), fasting blood-glucose through hospital diagnosis
12.7mmol/L, soreness and weakness of waist and knees, metal fatigue is hard and dry.The Chinese medicine capsules of the embodiment of the present invention 1 are taken, twice daily,
It is within two months a course for the treatment of.Checked after one course for the treatment of, fasting blood-glucose 5.8mmoI/L, glucose in urine (one), and two courses for the treatment of of continuous treatment,
It is discontinued, follow-up is not recurred so far.
Model case 3：Certain is solved, man, 42 years old.Main suit's fasting blood-glucose 10mmol/l or so always, body is partially fat, with dizziness
Tired, abdominal distension uncomfortable in chest, hidrosis are hard and dry, thirsty many drinks.The Chinese medicine capsules of the embodiment of the present invention 1 are taken, twice daily,
It is within two months a course for the treatment of.Treat after a course for the treatment of, patient feels that all diseases mitigate, and advises it to be continuing with, and is detected after two courses for the treatment of
Fasting blood-glucose is down to 5.6mmol/l, and eyesight is clearly better, and continues to take after 2 courses for the treatment of, glycemic control in normal range (NR), and
And blood fat and blood pressure is also back to normal.
Model case 4：Cui, female, 60 years old.Main suit suffers from diabetes 1 year, detects fasting blood-glucose 8.7mmoL/L, glycerine three
Fat 1.83mmoL/L, HDL 0.96mmoL/L, low-density lipoprotein 5.02mmoL/L, T-CHOL 6.95mmoL/
L, is diagnosed as hyperlipidemia with diabetes.The Chinese medicine capsules of the embodiment of the present invention 1 are taken, are within two months one twice daily
The individual course for the treatment of.Checked after one course for the treatment of, indices are normal, follow-up blood fat no abnormality seen after 1 year.
Model case 5：Business, man, 36 years old.Main suit is felt run-down recent months, and build is become thin, although appetite increase,
But body weight has no growth, pain in low back and legs is hard and dry, and is type ii diabetes through hospital diagnosis.Take the embodiment of the present invention 1
Chinese medicine capsules, two months are a course for the treatment of twice daily.Checked after one course for the treatment of, fasting blood-glucose 5.5mmoI/L, body weight increases
Plus, and the elimination of all diseases.
Claims (8)
1. a kind of Chinese medicine composition for treating diabetes, it is characterised in that be made up of the Chinese medicine of following parts by weight：Ramulus euonymi 15 is sweet
Chrysanthemum leaf 10, snake lotus 6, corn stigma 15, balsam pear 15, potentilla discolor 15, Chinese lizardtail rhizome 10 is made.
2. Chinese medicine composition as claimed in claim 1, it is characterised in that formulation is pill, tablet, capsule, powder, particle
Agent, oral liquid.
3. Chinese medicine composition as claimed in claim 1, it is characterised in that formulation is pill.
4. the preparation method of the Chinese medicine composition as described in 1-3 any claims, it is characterised in that comprise the following steps：
(1) Ramulus euonymi, is weighed, stevia rebaudian leaf, She Lian, corn stigma, balsam pear, potentilla discolor, Chinese lizardtail rhizome dry, pulverize into smalls；
(2), the decocting of 6-10 times of volume is added to boil twice the smalls of step (1), first time 2-5 hour, second of 0.5-2 is small
When, collecting decoction；
(3), the decocting liquid of step (2) is filtered, 60 DEG C of filtrate is concentrated under reduced pressure into the clear cream that relative density is 1.02-1.15, then
The filtration of 200-400 mesh sieves is crossed while hot, and filtrate is spray-dried, and produces spray powder.
5. preparation method as claimed in claim 4, it is characterised in that：Step (2) is plus the decocting of 6-8 times of volume is boiled twice,
First time 2-3.5 hour, second 1-2 hours, collecting decoction；The spray drying condition of step (3) is：Outlet temperature 70-100
DEG C, 130-160 DEG C of inlet temperature, flow velocity 8-12%, 25-30 DEG C of feed temperature.
6. preparation method as claimed in claim 4, it is characterised in that the spray powder of step (3) is crossed into 20-40 mesh sieves, optionally
Pharmaceutically acceptable auxiliary material is added, pill, tablet, capsule, powder, granule, oral liquid is made.
7. preparation method as claimed in claim 4, it is characterised in that the spray powder of step (3) is crossed into 20-40 mesh sieves, optionally
Pharmaceutically acceptable auxiliary material is added, pill is made.
8. purposes of the Chinese medicine composition in the medicine for preparing treatment diabetes as described in 1-3 any claims.
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Citations (1)
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| CN103461997A (en) * | 2013-08-13 | 2013-12-25 | 娄志 | Hypoglycemic composite fruit and vegetable powder and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103461997A (en) * | 2013-08-13 | 2013-12-25 | 娄志 | Hypoglycemic composite fruit and vegetable powder and preparation method thereof |
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| Title |
|---|
| 白羽连玉合剂对四氧嘧啶诱导的大鼠糖尿病作用的实验研究;邓棋卫等;《时珍国医国药》;20101231;第1910-1911页 * |
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