CN106266618A - A kind of for endo-medicine treating diabetes and preparation method thereof - Google Patents

A kind of for endo-medicine treating diabetes and preparation method thereof Download PDF

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Publication number
CN106266618A
CN106266618A CN201610814807.8A CN201610814807A CN106266618A CN 106266618 A CN106266618 A CN 106266618A CN 201610814807 A CN201610814807 A CN 201610814807A CN 106266618 A CN106266618 A CN 106266618A
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herba
medicine
endo
radix
diabetes
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孙素蓉
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Sichuan Juhao Biotechnology Co Ltd
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Sichuan Juhao Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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Abstract

The invention belongs to field of traditional Chinese, purpose is a kind of endo-medicine for treating diabetes according to the traditional Chinese medical science, diabetes being recognized mechanism and providing, and each component of described medicine and mass parts ratio thereof are as follows: Herba Potentillae Discoloris 150~260g, Semen Euryales 150~320g, the Radix Astragali 90~380g, Fructus Trichosanthis 90~200g, Herba Dendrobii 60~160g, the Rhizoma Atractylodis Macrocephalae 30~160g, Herba Lespedezae Cuneatae 250~500g, the Radix Rehmanniae 120~350g, Radix Angelicae Sinensis 80~160g, Herba potentillae kleinianae 80~160g, Poria 150~260g;The medicine that the present invention provides is the Chinese prescription of a treating both the principal and secondary aspects of a disease.

Description

A kind of for endo-medicine treating diabetes and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of endo-medicine for treating diabetes, particularly supply The field of the endo-medicine that diabetics uses and preparation method thereof.
Background technology
Diabetes are a kind of metabolic diseases, particularly type Ⅱdiabetes mellitus, are the diseases that cause of one way of life mode, its Pathogenesis system is the most closely related with h and E factor, and the traditional Chinese medical science is thought: diabetes are owing to yin-Yang is unbalance, yin deficiency is scorching The hepatic and renal YIN deficiency caused, and then three-many-one-little occurs: i.e. polydipsia, polyphagia, polyuria, the symptom lost weight.Therefore the traditional Chinese medical science is to sugar The treatment of urine disease needs to catch liver nourishing, this important step of the kidney invigorating, and human body is carried out across-the-board regulation, makes Liver and kidney have the essence of abundance Gas, thus cure diabetes and complication.
So, just how to find a kind of medicine that can effectively treat above-mentioned diabetes, be that we are badly in need of to be solved at present Problem.
Summary of the invention
Along with the development of China's Chinese medicine, in treatment diabetes, people gradually appreciate Chinese traditional treatment The advantage of diabetes, and good effect, instant effect, without any side effects over the course for the treatment of, can allow the blood glucose of patient quickly The stable advantage such as within normal range, for the present situation of existing western medical treatment diabetes, it is an object of the invention to be to provide one Plant the endo-medicine for treating diabetes, to solve the most restorative problem of diabetics.This medicine is with common Chinese medicine be raw material.Can effectively treat above-mentioned diabetes.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide one to be used for treating diabetes Endo-medicine and preparation method thereof, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:
Herba Potentillae Discoloris 150~260g, Semen Euryales 150~320g, the Radix Astragali 90~380g, Fructus Trichosanthis 90~200g, Herba Dendrobii 60~160g, the Rhizoma Atractylodis Macrocephalae 30~160g, Herba Lespedezae Cuneatae 250~500g, the Radix Rehmanniae 120~350g, Radix Angelicae Sinensis 80~160g, Herba potentillae kleinianae 80~160g, Poria 150~ 260g。
A kind of for endo-medicine treating diabetes and preparation method thereof, it is characterised in that each group of described medicine Divide and mass parts ratio be as follows:
Herba Potentillae Discoloris 180~230g, Semen Euryales 200~280g, the Radix Astragali 150~340g, Fructus Trichosanthis 110~170g, Herba Dendrobii 80~135g, white Art 80~135g, Herba Lespedezae Cuneatae 300~420g, the Radix Rehmanniae 200~300g, Radix Angelicae Sinensis 100~135g, Herba potentillae kleinianae 100~135g, Poria 180 ~230g.
A kind of for endo-medicine treating diabetes and preparation method thereof, it is characterised in that described " preferred plan " Each component of medicine and mass parts ratio thereof are as follows:
Herba Potentillae Discoloris 200g, Semen Euryales 250g, Radix Astragali 300g, Fructus Trichosanthis 150g, Herba Dendrobii 115g, Rhizoma Atractylodis Macrocephalae 115g, Herba Lespedezae Cuneatae 360g, the Radix Rehmanniae 260g, Radix Angelicae Sinensis 115g, Herba potentillae kleinianae 115g, Poria 200g.
A kind of for endo-medicine treating diabetes and preparation method thereof, it is characterised in that described method includes as follows Step is prepared from:
A, above-mentioned raw materials Chinese medicine is picked decontamination and dust after, be ground into superfine end according to mass parts ratio stand-by;
B, the method preparing Chinese medicine capsules according to tradition, after being sieved by ground superfine myrrh thing, put in medicine device and mix Uniformly, capsule (the sealed rear total length of its capsule is 23.3mm, medicated powder capacity 0.4~0.5g/ grain), Jin Erfen then it are prepared as Dress seals.
A kind of for endo-medicine treating diabetes and preparation method thereof, it is characterised in that described instructions of taking is: will The capsule medicine prepared is to take three times a day, and the morning, noon and afternoon service once, and dosage 8g/time, within three months, it is a treatment Journey, can make blood sugar recovery normal two to three courses for the treatment of.Effective percentage is up to 98%.
Each raw material Chinese medicine in prescription of the present invention all has detailed note in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine Carry.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Herba Potentillae Discoloris, nature and flavor: hardship sweet, micro-, flat, nontoxic, there is heat clearing away, removing toxic substances, effect of dysentery relieving hemostasis, be used for treating women red in vain Band and menorrhagia disease, according to clinical verification, this product has therapeutic efficiency to diabetes;
Semen Euryales, nature and flavor: sweet, puckery, flat, there is reinforcing the kindey to control nocturnal emission, effect of spleen reinforcing stopping leak, be used for treating seminal emission, nebulousurine, stranguria with turbid discharge, band Under, incontinence of urine, loose stool and diarrhea;
The Radix Astragali, nature and flavor: sweet, tepor, there is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation, be used for treating the deficiency of vital energy Weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty burst, burst for a long time do not hold back, The diseases such as blood deficiency dull yellowish colored skin, interior-heat are quenched one's thirst, chronic nephritis proteinuria, diabetes;
Fructus Trichosanthis, nature and flavor: sweet in the mouth, micro-hardship, cold in nature, there is removing heat-phlegm, wide born of the same parents' eliminating stagnation, moisturize effect of laxation, be used for treating clear Transconversion into heat expectorant, wide born of the same parents' eliminating stagnation, moisturize the diseases such as laxation;
Herba Dendrobii, nature and flavor: sweet, be slightly cold, there is the stomach reinforcing that promotes the production of body fluid, nourishing YIN and clearing away heat, lung moistening kidney tonifying, effect of the strong waist of improving eyesight, be used for treating Consumption of body fluid caused by febrile disease, xerostomia excessive thirst, deficiency of stomach-Yin, stomachache retch, dryness of the lung dry cough, deficiency-heat do not move back, the moon hinders that mesh is dark, waist knee joint is weak;
The Rhizoma Atractylodis Macrocephalae, nature and flavor: bitter in the mouth, sweet, warm in nature, there is invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, be used for treating temper The few abdominal distention of weakness, spiritlessness and weakness, lack of appetite, big loose stool are thin, fluid-retention stagnating in the interior, dysuria, edema, dizziness due to fluid-retention, temperature numbness are ached, gas The empty disease such as spontaneous perspiration, frequent fetal movement;
Herba Lespedezae Cuneatae, nature and flavor: hardship sweet, micro-, flat, there is clearing away heat-damp and promoting diuresis, help digestion except long-pending, effect of expelling phlegm for arresting cough, be used for treating children's Infantile malnutrition, dyspepsia, gastroenteritis, bacillary dysentery, stomachache, icterohepatitis, oedema due to nephritis, leucorrhea, stomatitis, cough, Tracheitis, herpes zoster, venom are controlled in external;
The Radix Rehmanniae, nature and flavor: Radix Rehmanniae, sweet, bitter, there is effect of Radix Rehmanniae, clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis, be used for treating calentura wound The moon, crimson tongue excessive thirst, send out speckle dermexanthesis, haematemesis, epistaxis, laryngopharynx swelling and pain, Radix Rehmanniae, clearing away heat and cooling blood, yin nourishing, the disease such as promote the production of body fluid;
Radix Angelicae Sinensis, nature and flavor: warm in nature, sweet in the mouth is pungent, there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, be used for treating blood deficiency, Shallow complexion, dizziness cardiopalmus, blood deficiency or have concurrently the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea, deficient cold type stomachache, the coronary heart disease heart strand Bitterly, the disease such as rheumatic arthralgia, traumatic injury;
Herba potentillae kleinianae, nature and flavor: toil, cool, there is effect of heat clearing away, removing toxic substances, be used for treating infantile convulsion high heat, malaria, cough, have sore throat, wet The diseases such as numbness, carbuncle tinea skin ulcer, erysipelas, prurigo, Serpentis, insect bite wound;
Poria, nature and flavor: sweet, light, flat, there is effect of eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, be used for treating dysuria, Edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, have loose bowels, palpitation and restlessness, insomnia forgetfulness, the disease such as seminal emission nebulousurine.
Medicine of the present invention is differential diagnosis of diseases based on TCM treatment of diabetes and the dialectical principle combined, from pharmacological action and work Think by mechanism: with regard to diabetes, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has above-mentioned disease very well Therapeutic effect.
Detailed description of the invention
The present invention is aiming at the treatment of above-mentioned diabetes and a kind of Chinese medicine formula of proposing, uses medicine prepared by this formula Thing good drug efficacy, instant effect, it is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Tool below in conjunction with the present invention Body embodiment is described in further detail:
Embodiment 1:
A kind of endo-medicine for treating diabetes, it is characterised in that each component of described medicine and mass parts thereof are such as Shown in lower:
Herba Potentillae Discoloris 200g, Semen Euryales 250g, Radix Astragali 300g, Fructus Trichosanthis 150g, Herba Dendrobii 115g, Rhizoma Atractylodis Macrocephalae 115g, Herba Lespedezae Cuneatae 360g, the Radix Rehmanniae 260g, Radix Angelicae Sinensis 115g, Herba potentillae kleinianae 115g, Poria 200g.
Embodiment 2:
A kind of endo-medicine for treating diabetes, it is characterised in that each component of described medicine and mass parts thereof are such as Shown in lower:
Herba Potentillae Discoloris 230g, Semen Euryales 280g, Radix Astragali 340g, Fructus Trichosanthis 170g, Herba Dendrobii 135g, Rhizoma Atractylodis Macrocephalae 135g, Herba Lespedezae Cuneatae 420g, the Radix Rehmanniae 300g, Radix Angelicae Sinensis 135g, Herba potentillae kleinianae 135g, Poria 230g.
Embodiment 3:
A kind of endo-medicine for treating diabetes, it is characterised in that each component of described medicine and mass parts thereof are such as Shown in lower:
Herba Potentillae Discoloris 260g, Semen Euryales 320g, Radix Astragali 380g, Fructus Trichosanthis 200g, Herba Dendrobii 160g, Rhizoma Atractylodis Macrocephalae 160g, Herba Lespedezae Cuneatae 500g, the Radix Rehmanniae 350g, Radix Angelicae Sinensis 160g, Herba potentillae kleinianae 160g, Poria 260g.
Model case
Through clinical conditions diabetics totally 600 example, the age is 390 examples of more than 62 years old, only 210 examples be 62 years old with Under.591 examples of recovery from illness in 600 example patients, 9 invalid examples, total effective rate reaches 98.5%.

Claims (3)

1. the endo-medicine being used for treating diabetes, it is characterised in that each component of described medicine and mass parts ratio thereof As follows:
Herba Potentillae Discoloris 150~260g, Semen Euryales 150~320g, the Radix Astragali 90~380g, Fructus Trichosanthis 90~200g, Herba Dendrobii 60~160g, the Rhizoma Atractylodis Macrocephalae 30~160g, Herba Lespedezae Cuneatae 250~500g, the Radix Rehmanniae 120~350g, Radix Angelicae Sinensis 80~160g, Herba potentillae kleinianae 80~160g, Poria 150~ 260g。
Endo-medicine for treating diabetes the most according to claim 1, it is characterised in that each group of described medicine Divide and mass parts ratio be as follows:
Herba Potentillae Discoloris 180~230g, Semen Euryales 200~280g, the Radix Astragali 150~340g, Fructus Trichosanthis 110~170g, Herba Dendrobii 80~135g, white Art 80~135g, Herba Lespedezae Cuneatae 300~420g, the Radix Rehmanniae 200~300g, Radix Angelicae Sinensis 100~135g, Herba potentillae kleinianae 100~135g, Poria 180 ~230g.
3. according to described in claim 1 to 2 for treating the endo-medicine of diabetes, it is characterised in that described medicine each Individual component and mass parts ratio thereof are as follows:
Herba Potentillae Discoloris 200g, Semen Euryales 250g, Radix Astragali 300g, Fructus Trichosanthis 150g, Herba Dendrobii 115g, Rhizoma Atractylodis Macrocephalae 115g, Herba Lespedezae Cuneatae 360g, the Radix Rehmanniae 260g, Radix Angelicae Sinensis 115g, Herba potentillae kleinianae 115g, Poria 200g.
CN201610814807.8A 2016-09-12 2016-09-12 A kind of for endo-medicine treating diabetes and preparation method thereof Withdrawn CN106266618A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014077425A1 (en) * 2012-11-14 2014-05-22 한국한의학연구원 Pharmaceutical composition and functional health food containing paulownia extract for preventing or treating diabetes complications
CN104547237A (en) * 2014-12-25 2015-04-29 广东聚智诚科技有限公司 Traditional Chinese medicinal composition for treating diabetes and method for preparing traditional Chinese medicinal composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014077425A1 (en) * 2012-11-14 2014-05-22 한국한의학연구원 Pharmaceutical composition and functional health food containing paulownia extract for preventing or treating diabetes complications
CN104547237A (en) * 2014-12-25 2015-04-29 广东聚智诚科技有限公司 Traditional Chinese medicinal composition for treating diabetes and method for preparing traditional Chinese medicinal composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
焦素杰等: "《中华医学基础与疾病特色疗法》", 30 April 2016, 林科学技术出版社 *

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