CN105687586A - Medicine for stopping bleeding of acute soft-tissue injury and wound - Google Patents

Medicine for stopping bleeding of acute soft-tissue injury and wound Download PDF

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CN105687586A
CN105687586A CN201610052151.0A CN201610052151A CN105687586A CN 105687586 A CN105687586 A CN 105687586A CN 201610052151 A CN201610052151 A CN 201610052151A CN 105687586 A CN105687586 A CN 105687586A
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radix
medicine
blood
tissue injury
soft tissue
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梁建强
韩玲玲
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XINXIANG ZUOJINMING PHARMACEUTICAL CO Ltd
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XINXIANG ZUOJINMING PHARMACEUTICAL CO Ltd
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Abstract

The invention relates to a traditional Chinese medicine and particularly relates to a medicine for stopping bleeding of acute soft-tissue injury and wound. The medicine is prepared from the following components in parts by weight: 460g-500g of dragon blood, 58g-62g of mastic, 58g-62g of myrrh, 100g-110g of catechu, 46g-50g of radix notoginseng, 46g-50g of radix angelicae sinensis, 36g-40g of lignum dalbergiae odoriferae, 36g-40g of radix dipsaci, 36g-40g of rhizoma drynariae, 100g-110g of radix salviae miltiorrhizae and 36g-40g of radix astragali which are used as crude drugs. The medicine has the main functions of diminishing swelling, stopping pain and stopping bleeding, and is mainly used for treating the pain of traumatic blood stasis.

Description

A kind of medicine for acute soft tissue injury, wound hemostasis
Technical field
The present invention relates to a kind of Chinese medicine, particularly relate to a kind of medicine for acute soft tissue injury, wound hemostasis。
Technical background
Acute soft tissue injury mean a series of acute contusion that the tissue outside the following skeleton of human motion system, skin occurs or (with) laceration, the acute injury of the different situations of tissue and peripheral nerve, blood vessel such as including muscle, ligament, fascia, tendon, synovial membrane, fat, joint capsule, it it is clinical common external wounds illness, the existing mid-sales patent medicine treating this illness has YUNNAN BAIYAO, pill for traumatic injuries, Flos Carthami wet goods, have a certain curative effect, but hemostasis, pain relieving, detumescence speed undesirable。
Summary of the invention
The present invention provides a kind of medicine for acute soft tissue injury, wound hemostasis, and the present invention is good at detumescence, pain relieving, hemostasis on function cures mainly, and cures mainly traumatic blood stasis pain。
The technical solution adopted in the present invention is:
A kind of medicine for acute soft tissue injury, wound hemostasis, is made up of following component: Sanguis Draxonis 460g~500g, Olibanum 58g~62g, Myrrha 58g~62g, catechu 100g~110g, Radix Notoginseng 46g~50g, Radix Angelicae Sinensis 46g~50g, Lignum Dalbergiae Odoriferae 36g~40g, Radix Dipsaci 36g~40g, Rhizoma Drynariae 36g~40g, Radix Salviae Miltiorrhizae 100g~110g, Radix Astragali 36g~40g make as crude drug。
A kind of medicine for acute soft tissue injury, wound hemostasis, is made up of following component: Sanguis Draxonis 460g, Olibanum 58g, Myrrha 58g, catechu 100g, Radix Notoginseng 46g, Radix Angelicae Sinensis 46g, Lignum Dalbergiae Odoriferae 36g, Radix Dipsaci 36g, Rhizoma Drynariae 36g, Radix Salviae Miltiorrhizae 100g, Radix Astragali 36g make as crude drug。
A kind of medicine for acute soft tissue injury, wound hemostasis, is made up of following component: Sanguis Draxonis 480g, Olibanum 60g, Myrrha 60g, catechu 105g, Radix Notoginseng 48g, Radix Angelicae Sinensis 48g, Lignum Dalbergiae Odoriferae 38g, Radix Dipsaci 38g, Rhizoma Drynariae 38g, Radix Salviae Miltiorrhizae 105g, Radix Astragali 38g make as crude drug。
A kind of medicine for acute soft tissue injury, wound hemostasis, is made up of following component: Sanguis Draxonis 500g, Olibanum 62g, Myrrha 62g, catechu 110g, Radix Notoginseng 50g, Radix Angelicae Sinensis 50g, Lignum Dalbergiae Odoriferae 40g, Radix Dipsaci 40g, Rhizoma Drynariae 40g, Radix Salviae Miltiorrhizae 110g, Radix Astragali 40g make as crude drug。
A kind of preparation method for acute soft tissue injury, the medicine of wound hemostasis, specifically comprises the following steps that
A, take above-mentioned raw materials medicine, remove impurity;
B, under clean environment adopt superfine powder be broken into fine powder;
C, mix homogeneously, cross No. six sieve series and become capsule, every dress 0.4g, packaging, puts airtight, lucifuge, namely shady and cool dry place obtains Chinese medicine。
A kind of medicine for acute soft tissue injury, wound hemostasis, described Chinese medicine adopts micronizing to obtain crude drug fine powder, and crude drug fine powder particle diameter is less than 10~25 μm。
Fang Xie: in side, Sanguis Draxonis is sweet salty, enters pericardium, Liver Channel, for oral administration can clots absorbing pain relieving, external application can be stopped blooding, granulation promoting, holds back mouth, is the conventional key medicine of the external wounds illness such as traumatic injury, gold creates blood, wound does not conform to, and dose is several times as much as other medicine, therefore be monarch drug。
Olibanum, Myrrha all with eliminating stasis to stop pain for, because the two gas is fragrant, perfume (or spice) can be walked to alter and benefaction, thus can promoting the circulation of blood dissipating blood stasis, promoting the circulation of QI dredging collateral, blood diarrhea due to disorder of QI, then pain is from only, therefore for the special medicine of pain relieving, the two Chang Xiangwu is use, and treatment cellulitis skin ulcer swells, traumatic injury;The sweet temperature of Radix Notoginseng enters liver stomach, and dissipating blood stasis stops blooding, and subduing swelling and relieving pain is good at hemostasis especially;Catechu removing dampness, granulation promoting, sore, for the common medicine that routed skin ulcer is not held back;Radix Angelicae Sinensis Gan Xinwen, returns liver, the heart, spleen channel, sweet in the mouth and weigh, therefore specially can enrich blood, for enriching blood the first medicine, gas is light and pungent, therefore again can promoting the circulation of blood, activating collaterals to relieve pain;Above-mentioned five kinds of Chinese medicine is ministerial drug altogether, can help Sanguis Draxonis promoting blood circulation to remove blood stasis, has again and enriches blood, and analgesic hemostatic holds back the merit of mouthful granulation promoting。Gas row then blood, the stagnation of QI is blood clotting then, and the pungent temperature of Lignum Dalbergiae Odoriferae returns liver spleen channel, the special promoting flow of QI and blood of medicine, and can hemostasis and pain-relieving, with circulation of qi promoting in Lignum Dalbergiae Odoriferae blood with dissipating blood stasis;The Radix Astragali is sweet, tepor, returns lung, spleen, Liver Channel, and enriching spleen-QI is to help gastric qi;Rhizoma Drynariae hardship temperature enters kidney channel, invigorating the kidney and strengthening the bones;The bitter sweet temperature of Radix Dipsaci, can invigorating the liver and kidney, reuniting the fractured tendons and bones;Three share, and tonifying liver is with replenishing essence, and the kidney invigorating is with bone strengthening, and spleen reinforcing is with angry blood;Radix Salviae Miltiorrhizae bitter in the mouth, cold nature;The heart, spleen, liver, kidney blood system medicine, can break stagnated blood, mend fresh blood, special regulating menstruation arteries and veins, reason iliacus is ached;Five medicines share, and both can prevent from invading in traumatic stasis, accelerate blood stasis and dissipate, and can mend again internal organs to promote that injury of tendon and muscle fracture is recovered early, be adjuvant altogether。
The traditional Chinese medical science is thought, traumatic injury, injures QI and blood more, the then stagnation of QI of feeling frustrated, and blood trouble is blood stasis then, and traumatic injury is inevitable with pain, pain certainty wasting QI-blood, and blood stasis is jammed meridians, makes QI and blood cervical carcinoma with cachexia;Under physiological conditions, qi as the commander of blood, blood being the mother of qi, and QI and blood complements each other, if the stagnation of QI, blood clotting, otherwise, blood clotting is the stagnation of QI then;The blood stasis stagnation of QI or the meridians that are jammed, or stagnant in muscle, more there are blood circulating out of vessels resistance and skin and flesh fascia, cause meridians muscles functional activity of QI being not smooth, stop up stagnant obstructed, stagnation of QI and blood may bring about pain。
Adding Flos Carthami in some formula, and the effect of the Radix Salviae Miltiorrhizae in Flos Carthami and the present invention collides with each other, although two taste medicines all have function of promoting blood circulation to disperse blood clots, but nature and flavor are contrary, Flos Carthami is pungent, warm;Radix Salviae Miltiorrhizae is bitter, be slightly cold;Both can enter blood system and play function of promoting blood circulation to disperse blood clots, but the medicine contrary due to two taste nature and flavor uses simultaneously, function of promoting blood circulation to disperse blood clots does not increase and weakens on the contrary, it is impossible to reach therapeutic effect, and in side, pungent dry property medicine is more, pungent dry property medicine easily dissipates cloudy blood, therefore, new disease will not be caused again to cure the disease simultaneously, so, without Flos Carthami, use the theory of cloudy blood of avoiding in the red sage root formula side of may conform to dissipating instead。
Modern medical knowledge also indicates that traumatic injury is for standing direct wound, or the tissue of wound and long-term strain indirectly, occur in that microcirculation disturbance, due to capillary wall sepage or hemorrhage, cause the formation of the hypostasis thing of tissue, and there occurs aseptic inflammation, cause swollen tissue pain, if the absorption of hypostasis thing can not be promoted, adhesion will be produced, muscle, ischemic contracture can be there is in the adhesion of tendon, adhesion outside intraarticular, just cause the tetanic of joint, therefore the gastric qi of patient is strengthened, improve gasification function, it it is the key point for the treatment of traumatic injury。
The spleen and the stomach are interior-exteriorly related, the not normal digestion affecting stomach of the transportation capabilities of spleen, therefore add Radix Astragali enriching spleen-QI on Sanguis Draxonis recovers from injury scattered basis, and then increase gastric qi, improve the absorbability of food, with its process reaching to increase body reparation by strengthening the immunologic function of self, rather than simple supporting by medicine, also comply with the thought recuperated of modern, general hemorrhage with in various degree again of traumatic injury, therefore Radix Angelicae Sinensis replenishing and activating blood is added, the traditional Chinese medical science is thought, Radix Angelicae Sinensis sweet in the mouth and weigh, therefore specially can enrich blood, for the first medicine of enriching blood, its gas is light and pungent, therefore again can promoting the circulation of blood, invigorating middle warmer has, row has benefit, for the key medicine in blood, thus, it can be enriched blood, can invigorate blood circulation again, both can stimulate the menstrual flow, again can be active, modern pharmacology shows that Radix Angelicae Sinensis can also remarkably promote body hemopoietic function;" pharmacy dictionary " is said " when attribution energy regulating QI is nourished blood, QI and blood is made respectively to return to some extent, therefore named Radix Angelicae Sinensis ", visible, Radix Angelicae Sinensis speciality in taking good care of QI and blood, and QI and blood tune is freely the place of traumatic injury pathogenesis, drug for invigorating blood circulation and eliminating stasis totally has the effect of dissipation, cross to have used and will consume impairment of YIN blood, and activating blood and removing stasis drug contained in former side has pungent dry property mostly, and the course for the treatment of treating traumatic injury is general longer, so former side's drawback is in that in therapeutic process can consume impairment of YIN blood, increase the weight of QI-blood circulation burden, thus finally not reaching the effect for the treatment of, therefore, add Radix Angelicae Sinensis and mend weak point in its side, most drug for traumatic injuries is all to treat soft tissue injury, but some traumatic injury are again with a degree of fracture, therefore, we add Radix Salviae Miltiorrhizae, largely compensate for the drawback of existing drug for traumatic injuries, modern pharmacological research shows, Radix Salviae Miltiorrhizae has the formation promoting fracture callus later, and the flexural capacity of callus can be strengthened, it it is the medicine desirably treating bones and muscles injury, also the effect that having invigorates blood circulation cures the wound, Shennong's Herbal being said, Radix Salviae Miltiorrhizae is mainly used in abolishing the effect of abdominal mass, Compendium of Material Medica is carried, Radix Salviae Miltiorrhizae cures mainly arthralgia, extremity are unsuccessful, broken stagnated blood, tissue regeneration promoting blood;Evacuation of pus pain relieving, blood activating and promoting tissue regeneration the function such as puts on flesh as can be seen here, Radix Salviae Miltiorrhizae has the effect disappeared with promoting blood circulation and stopping pain of invigorating blood circulation, the Radix Salviae Miltiorrhizae property of medicine is partially cold, in blood circulation promoting and blood stasis dispelling, not easily consumption impairment of YIN blood, and be conducive to the new life of nutrient blood, there is the merit of subduing swelling and relieving pain, use same with hematonic Radix Angelicae Sinensis, has row and does not hinder, and mends and not stagnant effect, and by cardiovascular drugs Radix Salviae Miltiorrhizae and Lignum Dalbergiae Odoriferae compatibility, Xin Xiang dredges network, promoting blood circulation to remove obstruction in the collateral, the dynamics of blood circulation promoting and blood stasis dispelling in the side of enhancing, largely accelerate the dissipation of the blood stasis speckle that traumatic injury causes, to reach the purpose of detumescence。
Adopt technique scheme, actively providing the benefit that acquired by the present invention:
The present invention stops blooding soon, and spreading on hemorrhage place can stop blooding;
Pain relieving of the present invention is fast, gets final product pain relieving after taking the present invention 1 minute, and analgesia time was up to 12 hours;
The present invention subsides a swelling soon, for traumatic injury swelling, takes the present invention and can subside a swelling after one day;
Take a broad view of the present invention, on the basis of Sanguis Draxonis drug for traumatic injuries function, add the Radix Astragali to moisten foster taste, Radix Angelicae Sinensis blood circulation promoting and enriching, pungent dry property in mitigation side, avoid consumption impairment of YIN blood, tissue repair after Radix Salviae Miltiorrhizae promotion fracture, not only remain the marrow of medication, simultaneously from strengthening its body, and expand scope of medication, make up existing drug for traumatic injuries drawback, combine with modern medication theory and be used for treating bright spot and the innovative point that traumatic injury is we by the cardiovascular drugs that treatment obstruction of qi in the chest and cardialgia, side of body rib twinge, carbuncle skin ulcer swell。
Total seeing full invention, link closely pathogenesis, sends medicine pool amount, therefore has the merit of blood circulation promoting and blood stasis dispelling reducing swelling and alleviating pain, hemostasis, restoring and treating injured soft tissues, cures mainly various soft tissue injury, can promote again healing after fracture, it is adaptable to the diseases such as blood stasis pain that traumatic injury causes, swelling, hemorrhage and fracture。
Reasonable recipe of the present invention, science, there is effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, hemostasis, restoring and treating injured soft tissues, and achieve good effect by clinic application, concrete test situation is as follows:
One, diagnostic criteria
With reference to standard formulation relevant in " new Chinese medicine guideline of clinical investigations ":
1. having clear and definite trauma history, sharp ache after wound, there is swelling in various degree, ecchymosis, joint movement function obstacle in local;
2. injury tenderness is obvious, may occur in which the livid purple ecchymosis in local, and severe patient may occur in which ecchymosis, and the positive is levied in fluctuation;
3. having swelling or have scleroma, have a dull ache, it is limited that limb activity has in various degree;
4.X ray examination gets rid of dislocation and osteopathia。
Two, therapeutic scheme
For oral administration: three times on the one, each 0.4g;
External: once-a-day, mixes well with 1%~5% Chinese liquor of drug weight of the present invention, external application affected part;
It within 2 weeks, it is a course for the treatment of。
Three, efficacy assessment standard
Clinical cure: pain disappears, and swelling is disappeared, functional rehabilitation, can extensive recovery operation。It is zero after integrated value treatment;
Effective: pain, swelling disappear substantially, and joint motion is normal, do not affect work。After integrated value treatment, relatively treatment is front reduced for more than 2/3 (including 2/3);
Effective: pain, swelling alleviate, and joint motion makes moderate progress, or without significant change, after integrated value treatment, relatively treatment is front reduced for more than 1/2 (including 1/2);
Invalid: pain, swelling, unchanged or slightly alleviate compared with when joint motion is with first visit。Relatively treat front unchanged after integrated value treatment or reduce less than 1/2。
Four, statistical disposition
Group for oral administration: in 315 example patients, male 195 people, female 120 people, the ratio of men and women is 1.62:1。Between age 18~35,164 examples, account for 52.06%, 73 example between 36~45, account for 23.17%, and 78 example between 46~65 accounts for 24.77%。Joint portion damages 150 examples, accounts for 47.62%, damages 165 examples, account for 52.38% outside joint。Dampen 160 examples, account for 50.79%, sprain 155 examples, account for 49.21%。Light 67 examples of the state of an illness, account for 21.27%, and 145 example in the state of an illness accounts for 46.03%, and the state of an illness weighs 103 examples, accounts for 32.7%;
External group: in 100 example patients, male 65 people, female 35 people, the ratio of men and women is 1.86:1;
Between age 18~35,41 examples, account for 41%, 36 example between 36~45, account for 36%, and 23 example between 46~65 accounts for 23%。Joint portion damages 39 examples, accounts for 65%, and injury in 21 cases outside joint accounts for 35%。Dampen 50 examples, account for 50%, sprain 50 examples, account for 50%。Light 23 examples of the state of an illness, account for 23%, and 47 example in the state of an illness accounts for 47%, and the state of an illness weighs 30 examples, accounts for 30%;See following table:
For oral administration group of 315 example patient's state of an illness distribution situations of the present invention taken by table 1
The for oral administration group of 315 example patient trauma site distribution situations of the present invention taken by table 2
Damage location Number of cases Percentage rate (%)
Joint portion damages 150 47.62
Damage outside joint 165 52.38
The for oral administration group of 315 example patient trauma property distribution situations of the present invention taken by table 3
Damage character Number of cases Percentage rate (%)
Dampen 160 50.79
Sprain 155 49.21
External group 100 example patient's state of an illness distribution situation of the present invention taken by table 4
The state of an illness Number of cases Percentage rate (%)
Gently 23 23
In 47 47
Weight 30 30
The external group 100 example patient trauma site distribution situation of the present invention taken by table 5
Damage location Number of cases Percentage rate (%)
Joint portion damages 56 56
Damage outside joint 44 44
The external group 100 example patient trauma property distribution situation of the present invention taken by table 6
Damage character Number of cases Percentage rate (%)
Dampen 50 50
Sprain 50 50
Severity extent decision method
Table 7 soft tissue injury weight grade scale table
Note: pain, swelling item integration × 2
Normal: 0 point slight :≤12 points of moderates: 14-24 divides severe: more than 26 points
Swelling index=(hindering side-normal side)/normal side × 100% (same position Zhou Jing)
Attached: application visual simulation scale using method (VAS)
Group for oral administration: clinical cure 215 example, accounts for 68.25%, and effective 82 examples account for 26.03%, effective 18 examples, account for 5.72%, and invalid 0 example, in Table 8;
External group: clinical cure 57 example, accounts for 57%, and effective 40 examples account for 40%, effective 3 examples, account for 3%, and invalid 0 example, in Table 9;
To cardinal symptom and sign comparitive study in Table 10
Table 8 present invention group for oral administration total effects statistics
Project Recovery from illness Effective Effectively Invalid Add up to
Number of cases 215 82 18 0 315
Percentage rate % 68.25 26.03 5.72 0 100
Table 9 external group total effects statistics of the present invention
Project Recovery from illness Effective Effectively Invalid Add up to
Number of cases 57 40 3 0 100
Percentage rate % 57 40 3 0 100
Table 10 is to cardinal symptom and sign comparitive study table
From table 10, it can be seen that group for oral administration compares with before and after the pain of external group, swelling, dysfunction, tenderness symptom treatment, illustrate that pain that acute soft tissue injury occurs by invention medicine, swelling, dysfunction, tenderness symptom all have certain curative effect;
The curative effect of the different state of an illness is had any different, in Table 11,12:
Table 11 present invention group for oral administration curative effect statistics example (%) to the different state of an illness
The state of an illness Number of cases Recovery from illness Effective Effectively Invalid
Slightly 67 53(79.10) 12(17.91) 2(2.99) 0
Moderate 145 104(71.72) 33(22.76) 8(5.52) 0
Severe 103 58(56.31) 37(35.92) 8(7.77) 0
The table 12 external group of the present invention curative effect statistics example (%) to the different state of an illness
The state of an illness Number of cases Recovery from illness Effective Effectively Invalid
Slightly 25 18(72) 6(24) 1(4) 0
Moderate 50 28(56) 20(40) 2(4) 0
Severe 25 11(44) 14(56) 0(0) 0
No matter from table 11,12 it can be seen that group for oral administration or external group, checking through t, mutually comparing of the interior severity extent of group, P < 0.05, illustrate that its curative effect and state of an illness weight have obvious relation。Group for oral administration and external group, check through t, and between group, identical severity extent compares, P > 0.05, no significant difference, illustrates that this medicine is for oral administration and has equal curative effect with external;
Treatment time and curative effect also have certain relation, in Table 13,14
Table 13 present invention group treatment time for oral administration and therapeutic effect relationship example (%)
Time Number of cases Recovery from illness Effective Effectively Invalid
One week 315 87(27.62) 114(36.19) 108(34.29) 6(1.9)
Two weeks 315 215(68.25) 82(26.03) 18(5.72) 0
Table 14 external of the present invention group treatment time and therapeutic effect relationship example (%)
Time Number of cases Recovery from illness Effective Effectively Invalid
One week 100 40(40) 34(34) 24(24) 2(2)
Two weeks 100 57(57) 40(40) 3(3) 0
No matter from table 13,14 it can be seen that group for oral administration or external group, different course compares, illustrate this Drug therapy acute soft tissue injury curative effect be in time incremental and increase;
Damage location and therapeutic effect relationship are in Table 15,16
Table 15 present invention group for oral administration damage location and therapeutic effect relationship example (%)
As can be seen from Table 15, joint part compares with outside joint, P > 0.05, illustrates that medicine of the present invention is for oral administration substantially equivalent to the therapeutic effect of damage location, unrelated with position
Table 16 external group damage location of the present invention and therapeutic effect relationship example (%)
As can be seen from Table 16, joint part compares with outside joint, P > 0.05, illustrates that medicine external of the present invention is substantially equivalent to the therapeutic effect of damage location, unrelated with position;
Damage character and therapeutic effect relationship are in Table 17,18
Table 17 present invention group damage character for oral administration and therapeutic effect relationship example (%)
As can be seen from Table 17, sprain and compare with contusion, P > 0.05, illustrate that the curative effect of medicine of the present invention is unrelated with damage character, there is identical therapeutic effect
Table 18 external group damage character of the present invention and therapeutic effect relationship example (%)
As can be seen from Table 18, spraining of external group is compared with contusion, P > 0.05, illustrates that the curative effect of medicine of the present invention is unrelated with damage character, has identical therapeutic effect。
Detailed description of the invention
Hereinafter specific embodiment of the invention is further illustrated。
Embodiment 1
The present invention is made up of following crude drug: Sanguis Draxonis 460g, Olibanum 58g, Myrrha 58g, catechu 100g, Radix Notoginseng 46g, Radix Angelicae Sinensis 46g, Lignum Dalbergiae Odoriferae 36g, Radix Dipsaci 36g, Rhizoma Drynariae 36g, Radix Salviae Miltiorrhizae 100g, Radix Astragali 36g make as crude drug, and preparation method is:
A, take above-mentioned raw materials medicine, remove impurity;
B, under clean environment adopt superfine powder be broken into fine powder;
C, mix homogeneously, cross No. six sieve series and become capsule, every dress 0.4g, packaging, puts airtight, lucifuge, namely shady and cool dry place obtains Chinese medicine。
Embodiment 2
The present invention is made up of following crude drug: Sanguis Draxonis 480g, Olibanum 60g, Myrrha 60g, catechu 105g, Radix Notoginseng 48g, Radix Angelicae Sinensis 48g, Lignum Dalbergiae Odoriferae 38g, Radix Dipsaci 38g, Rhizoma Drynariae 38g, Radix Salviae Miltiorrhizae 105g, Radix Astragali 38g make as crude drug, and preparation method is:
A, take above-mentioned raw materials medicine, remove impurity;
B, under clean environment adopt superfine powder be broken into fine powder;
C, mix homogeneously, cross No. six sieve series and become capsule, every dress 0.4g, packaging, puts airtight, lucifuge, namely shady and cool dry place obtains Chinese medicine。
Embodiment 3
The present invention is made up of following crude drug: Sanguis Draxonis 500g, Olibanum 62g, Myrrha 62g, catechu 110g, Radix Notoginseng 50g, Radix Angelicae Sinensis 50g, Lignum Dalbergiae Odoriferae 40g, Radix Dipsaci 40g, Rhizoma Drynariae 40g, Radix Salviae Miltiorrhizae 110g, Radix Astragali 40g make as crude drug, and preparation method is:
A, take above-mentioned raw materials medicine, remove impurity;
B, under clean environment adopt superfine powder be broken into fine powder;
C, mix homogeneously, cross No. six sieve series and become capsule, every dress 0.4g, packaging, puts airtight, lucifuge, namely shady and cool dry place obtains Chinese medicine。
The embodiment of the above, simply presently preferred embodiments of the present invention, and the practical range of the unrestricted present invention, therefore all equivalence changes done according to the structure described in the scope of the claims of the present invention, feature and principle or modify, all should be included in the present patent application the scope of the claims。

Claims (6)

1. the medicine for acute soft tissue injury, wound hemostasis, it is characterized in that, be made up of following component: Sanguis Draxonis 460g~500g, Olibanum 58g~62g, Myrrha 58g~62g, catechu 100g~110g, Radix Notoginseng 46g~50g, Radix Angelicae Sinensis 46g~50g, Lignum Dalbergiae Odoriferae 36g~40g, Radix Dipsaci 36g~40g, Rhizoma Drynariae 36g~40g, Radix Salviae Miltiorrhizae 100g~110g, Radix Astragali 36g~40g make as crude drug。
2. a kind of medicine for acute soft tissue injury, wound hemostasis according to claim 1, it is characterized in that, be made up of following component: Sanguis Draxonis 460g, Olibanum 58g, Myrrha 58g, catechu 100g, Radix Notoginseng 46g, Radix Angelicae Sinensis 46g, Lignum Dalbergiae Odoriferae 36g, Radix Dipsaci 36g, Rhizoma Drynariae 36g, Radix Salviae Miltiorrhizae 100g, Radix Astragali 36g make as crude drug。
3. a kind of medicine for acute soft tissue injury, wound hemostasis according to claim 1, it is characterized in that, be made up of following component: Sanguis Draxonis 480g, Olibanum 60g, Myrrha 60g, catechu 105g, Radix Notoginseng 48g, Radix Angelicae Sinensis 48g, Lignum Dalbergiae Odoriferae 38g, Radix Dipsaci 38g, Rhizoma Drynariae 38g, Radix Salviae Miltiorrhizae 105g, Radix Astragali 38g make as crude drug。
4. a kind of medicine for acute soft tissue injury, wound hemostasis according to claim 1, it is characterized in that, be made up of following component: Sanguis Draxonis 500g, Olibanum 62g, Myrrha 62g, catechu 110g, Radix Notoginseng 50g, Radix Angelicae Sinensis 50g, Lignum Dalbergiae Odoriferae 40g, Radix Dipsaci 40g, Rhizoma Drynariae 40g, Radix Salviae Miltiorrhizae 110g, Radix Astragali 40g make as crude drug。
5. a kind of preparation method for acute soft tissue injury, the medicine of wound hemostasis according to Claims 1 to 4 any one, it is characterised in that specifically comprise the following steps that
A, take above-mentioned raw materials medicine, remove impurity;
B, under clean environment adopt superfine powder be broken into fine powder;
C, mix homogeneously, cross No. six sieve series and become capsule, every dress 0.4g, packaging, puts airtight, lucifuge, namely shady and cool dry place obtains Chinese medicine。
6. a kind of medicine for acute soft tissue injury, wound hemostasis according to claim 5, it is characterised in that described Chinese medicine adopts micronizing to obtain crude drug fine powder, and crude drug fine powder particle diameter is less than 10~25 μm。
CN201610052151.0A 2016-01-19 2016-01-19 Medicine for stopping bleeding of acute soft-tissue injury and wound Pending CN105687586A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113144018A (en) * 2021-04-07 2021-07-23 重庆三峡医药高等专科学校 Traditional Chinese medicine composition for treating blunt injury of soft tissues and extract and application thereof
CN113827679A (en) * 2021-11-09 2021-12-24 上海市宝山区中西医结合医院(上海中医药大学附属曙光医院宝山分院) Traditional Chinese medicine composition for treating stable angina pectoris qi deficiency phlegm stasis syndrome and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1985903A (en) * 2006-12-26 2007-06-27 张志平 Dead bone regenerating bolus for treating aseptic femoral head necrosis
CN102205020A (en) * 2011-05-18 2011-10-05 王法印 Traditional Chinese medicine for treating traumatic injury
CN102274365A (en) * 2011-06-30 2011-12-14 王奇 Traditional Chinese medicine powder for treating bedsore

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1985903A (en) * 2006-12-26 2007-06-27 张志平 Dead bone regenerating bolus for treating aseptic femoral head necrosis
CN102205020A (en) * 2011-05-18 2011-10-05 王法印 Traditional Chinese medicine for treating traumatic injury
CN102274365A (en) * 2011-06-30 2011-12-14 王奇 Traditional Chinese medicine powder for treating bedsore

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
胡志忠: "龙血竭在急性软组织损伤中的应用体会", 《中国社区医生.医学专业》 *
高佃华: "跌打七厘片联合龙血竭外用治疗急性软组织损伤128例观察", <中华中医药学会中医药治疗软组织损伤学术交流会论文汇编> *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113144018A (en) * 2021-04-07 2021-07-23 重庆三峡医药高等专科学校 Traditional Chinese medicine composition for treating blunt injury of soft tissues and extract and application thereof
CN113144018B (en) * 2021-04-07 2022-03-25 重庆三峡医药高等专科学校 Traditional Chinese medicine composition for treating blunt injury of soft tissues and extract and application thereof
CN113827679A (en) * 2021-11-09 2021-12-24 上海市宝山区中西医结合医院(上海中医药大学附属曙光医院宝山分院) Traditional Chinese medicine composition for treating stable angina pectoris qi deficiency phlegm stasis syndrome and application thereof

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Application publication date: 20160622