CN105582333A - Okra wine capable of preserving health and tonifying kidneys and preparation method thereof - Google Patents

Okra wine capable of preserving health and tonifying kidneys and preparation method thereof Download PDF

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CN105582333A
CN105582333A CN201610097297.7A CN201610097297A CN105582333A CN 105582333 A CN105582333 A CN 105582333A CN 201610097297 A CN201610097297 A CN 201610097297A CN 105582333 A CN105582333 A CN 105582333A
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parts
extract
okra
wine
root
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彭海英
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Chen Junjie
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Priority to PCT/CN2016/103573 priority patent/WO2017143798A1/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • C12G3/05Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides
    • C12G3/055Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides extracted from plants
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    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
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Abstract

The invention provides an okra wine capable of preserving health and tonifying kidneys and a preparation method thereof. The okra wine is prepared from the following components in parts by weight: 3-10 parts of okra extract, 10-20 parts of Chinese wolfberry extract, 3-10 parts of tribulus terrestris extract, 1-5 parts of propolis, 10-20 parts of Chinese yam, 5-15 parts of herba cistanche, 3-10 parts of angelica, 3-10 parts of eucommia, 3-10 parts of astragalus root, 3-10 parts of seeds of wild jujubes, 5-15 parts of fleece-flower root, 3-10 parts of white peony root, 5-15 parts of dendrobium, 3-10 parts of dogwood, 3-10 parts of rehmannia root, 5-15 parts of tuckahoe, 3-10 parts of rhizoma alismatis, 10-20 parts of licorice, 20-40 parts of honey and 1000-2000 parts of white spirit. The okra wine is reasonable in formula; through oxidative decoloration, macroporous resin decoloration and adsorption decoloration, the color of the wine is more clear and beautiful; and by adding the okra extract, the Chinese wolfberry extract and the tribulus terrestris extract, the effect of the okra wine can be further enhanced.

Description

A kind of health kidney tonifying okra wine and preparation method thereof
Technical field
The present invention relates to a kind of health preserving wine.
Background technology
The traditional Chinese medical science thinks that the kidney being the origin of congenital constitution, built-in nephroyin and nephroyang. The habits and customs accumulation that mostly is for a long time bad of suffering from a deficiency of the kidney forms, along withThe quickening of live and work rhythm, the pressure that people bear is also increasing, and the general level of the health is on a declining curve year by year, and occursSuffer from a deficiency of the kidney, insufficiency of vital energy and blood etc. Suffer from a deficiency of the kidney and be divided into the deficiency of Yin and the deficiency of yang, mostly be and roll up for a long time disease, can't suddenly mend it with anxious medicine, simplyEstablishing-Yang meeting is run counter to desire, and makes health weaker.
Alcoholic strength temperature, taste is pungent and bitter sweet, has warm promoting blood circulation, the loose efficacy of a drug of a surname, warm stomach, the dispersing wind and cold of dispelling, rouses oneself the effects such as yang-energy.By the health care product that improve the health and wine " molten ", in the health-care white spirit of one, not only preparation is convenient but also safe and effective. InThe white wine of high alcohol content is a kind of good medium polar solvent, can be by health care the active ingredient in food materials as alkaloid, tannin,The leachings such as volatile oil, organic acid, resin, carbohydrate and pigment, can health care, beauty treatment moisturizing; Also can do aftercare and dayOften drink use and promote longevity.
Summary of the invention
For above-mentioned technical problem, the invention provides a kind of health kidney tonifying okra wine and preparation method thereof. Health of the present invention is mendedKidney okra wine is made up of the component of following weight portion: 3~10 parts of Abelmoschus Esculentus Linn extracts, 10~20 parts of wolfberry fruit extracts, tribulus terrestris3~10 parts of extracts, 1~5 part of propolis, 10~20 parts of Chinese yams, 5~15 parts of saline cistanches, 3~10 parts of Radix Angelicae Sinensis, 3~10 parts of the barks of eucommia,3~10 parts of the Radixs Astragali, 3~10 parts of spina date seeds, 5~15 parts of the fleece-flowers root, 3~10 parts of the root of herbaceous peonys, 5~15 parts of the stems of noble dendrobium, Fructus Corni 3~10Part, 3~10 parts of glutinous rehmannia, 5~15 parts, Poria cocos, 3~10 parts of rhizoma alismatis, 10~20 parts, Radix Glycyrrhizae, 20~40 parts of honey, white wine 1000~500Part.
Further, formed by the component of following weight portion: 5~8 parts of Abelmoschus Esculentus Linn extracts, 12~18 parts of wolfberry fruit extracts, thorn5~8 parts of tribulus fruit extracts, 2~4 parts of propolis, 12~18 parts of Chinese yams, 8~12 parts of saline cistanches, 5~8 parts of Radix Angelicae Sinensis, the bark of eucommia 5~8Part, 5~8 parts of the Radixs Astragali, 5~8 parts of spina date seeds, 8~12 parts of the fleece-flowers root, 5~8 parts of the root of herbaceous peonys, 8~12 parts of the stems of noble dendrobium, Fructus Corni 5~8Part, 5~8 parts of glutinous rehmannia, 8~12 parts, Poria cocos, 5~8 parts of rhizoma alismatis, 12~18 parts, Radix Glycyrrhizae, 25~35 parts of honey, white wine 1200~1800Part.
Particularly, formed by the component of following weight portion: 6 parts of Abelmoschus Esculentus Linn extracts, 15 parts of wolfberry fruit extracts, tribulus terrestris are extracted6 parts of things, 3 parts of propolis, 15 parts of Chinese yams, 10 parts of saline cistanches, 6 parts of Radix Angelicae Sinensis, 6 parts of the barks of eucommia, 6 parts of the Radixs Astragali, spina date seed 6Part, 10 parts of the fleece-flowers root, 6 parts of the root of herbaceous peonys, 10 parts of the stems of noble dendrobium, 6 parts of Fructus Cornis, 6 parts of glutinous rehmannia, 10 parts, Poria cocos, 6 parts of rhizoma alismatis,15 parts, Radix Glycyrrhizae, 30 parts of honey, 1500 parts of white wine.
Wherein, the alcoholic strength of described white wine is 40~60%.
The preparation method of health kidney tonifying okra wine of the present invention comprises the following steps:
(1). by Chinese yam, saline cistanche, Radix Angelicae Sinensis, the bark of eucommia, spina date seed, the fleece-flower root, the root of herbaceous peony, the stem of noble dendrobium, Fructus Corni, glutinous rehmannia, FuSiberian cocklebur, rhizoma alismatis and Radix Glycyrrhizae are cleaned, cut into slices after sterilizing, oven dry;
(2). section and Abelmoschus Esculentus Linn extract, wolfberry fruit extract, tribulus terrestris extraction, propolis, honey that step (1) is made addEnter in white wine, stir propolis and honey are dissolved;
(3). the medicinal liquor that step (2) is made joins in the wine jar through sterilizing, and sealing stores 40~60 days at 15~25 DEG C.
Particularly, the preparation method of described Abelmoschus Esculentus Linn extract is: after tender okra pod is cleaned, put into 90~100 DEG C of hot waterAfter 3~5min, take out, be cooled to room temperature, add in the water of 5 times of weight and wear into slurries shape, the centrifugal 1~3min of 3000~5000r/minAfter discard insoluble matter, supernatant is described Abelmoschus Esculentus Linn extract.
Particularly, the preparation of described wolfberry fruit extract comprises the following steps:
(1). matrimony vine is shone to dry grinding, matrimony vine powder is added to the 0.5~3h that refluxes in the extract a of 5 times of weight, abandon after being cooled to room temperatureDesolventizing,
(2). the last residue of step (1) is added to the 1~3h that refluxes in the ethanol of 3 times of weight, discard solvent after being cooled to room temperature,
(3). the last residue of step (2) is added in 10 times of weight water, add sodium hydrate regulator solution pH value to 9~11,75~90 DEG CLower ultrasonic extraction 30min~2h, extracts 2 times altogether, merges extract extract, adds ethanol to make its precipitation,
(4). precipitation is leached, add water and after redissolution, add sodium hydrate regulator solution pH value to 8.0 completely, add 1/20 volumeThe mass fraction hydrogenperoxide steam generator that is 30%, stir 0.5~1h at 60 DEG C, adding ethanol after cooling precipitates again, and gained is precipitatedBe drying to obtain described wolfberry fruit extract.
Wherein, described extract a is the mixed solution that benzinum and acetone volume ratio are 1: 1.
Particularly, the preparation of described tribulus terrestris extraction comprises the steps:
(1). tribulus terrestris fruit is dried to rear pulverizing, in the ethanolic solution that the percent by volume that adds 5 times of weight is 50~80%, reflux1~2h, lets cool to room temperature, gets supernatant after centrifugal;
(2). the supernatant that step (1) the is made large pore resin absorption column of flowing through adsorbs, and uses successively 3~5 post bed bodies after upper propThe percent by volume of long-pending water and 3~5 bed volumes is that 10~30% ethanolic solution washes away color, then uses percent by volumeBe 60~90% ethanolic solution wash-out, collect eluent, be dried to medicinal extract, to obtain final product.
Particularly, described macroporous absorbent resin is HPD300 macroreticular resin.
In component of the present invention:
Okra is containing 2.5 grams, protein, 0.1 gram, fat, 2.7 grams of carbohydrates, cellulose A660 international unit. Vitamin B1,0.2 milligram, 0.06 milligram of vitamin B2,44 milligrams of vitamins, 81 milligrams of calcium, 63 milligrams, phosphorus, 0.8 milligram of iron, andContain a large amount of stick-slip juice, in its juice, contain and be mixed with pectin, the compositions such as cow's milk glycan and my glycan, its pectin is solvableProperty fiber, have strong stomach, nourishing negative and positive effect.
Matrimony vine is nourishing liver and kidney, benefiting shrewd head. Lose for consumptive disease essence, soreness of waist and knee joint, dizzy tinnitus, interior heat is quenched one's thirst, and the deficiency of blood is sallow,Blurred vision is not clear. Immunity is had to facilitation, there is immunoregulation effect simultaneously; Can improve plasma testosterone level, play strong effect;Hematopoiesis function is had to facilitation; Normal healthy people is also had to remarkable effect in increasing leukocyte; Anti-ageing, anti-sudden change in addition, anti-swollenKnurl, reducing blood lipid, protect the liver and AFL, hypoglycemic, hypotensive activity. Calcic 112.50mg in every 100 grams of matrimony vines, slightly fineDimension 7.78g, carbohydrate 57.82g, phosphorus 203.10mg, crude fat 7.14g, ascorbic acid 18.4g, iron 8.42mg,Crude protein 12.10g, niacin 4.32g, thiamine 0.153mg, riboflavin 1.27mg, carrotene 7.38g, sugarMatter 46.50mg.
It is silver-colored linden glucoside that tribulus terrestris contains puncture vine glucoside, Kaempferol, and Kaempferol-glycoside, Kaempferol-rutinoside, Quercetin,Vitamin C, also containing diosgenin, peroxidase etc. Fructus Tribulus total saponins can promote the sexual organ development of mouse childhood,Illustrate that it has the effect of promoting sexual gland hormone sample, its pharmacological action is that first Hypothalamic Stimulation discharges GnRF, the latterRealize by anterior pituitary again.
Chinese yam taste is sweet, property flat, returns spleen, lung, kidney channel. Compendium of Material Medica is pointed out: Chinese yam control weakness, treat general debility,Decaptitate seborrheic dematitis, only pain in the back, except dysphoria with smothery sensation, bushing unsaturated vapor, reach heart hole, many accounts, kidney-nourishing gas, strengthening the spleen and stomach, antidiarrheal dysentery,Profit fur, raw swollen, the hard poison of subsides of smashing can be controlled ". Chinese yam contains glutinous albumen, amylase, saponin(e, free amino acid, polyphenol oxidaseDeng material, and content is compared with horn of plenty, has tonic effect, is the good merchantable brand of tonic, has the effect of strong body, nourishing kidney and replenishing pneuma.
Saline cistanche taste is sweet, salty, warm in nature; Return kidney; Large intestine channel. Kidney-replenishing; Benefiting essence-blood; Ease constipation road. Main decline of kidney-YANG; Essence and bloodThe impotence of deficiency; Seminal emission; Gonorrhoea; The frequent micturition heeltap; Pain in the back flaccidity of lower limbs; Tinnitus order flower; Menstruation is spread out the phase; Fertility; Intestines are just drySecret etc.
Fleece-flower root bitter, sweet, puckery, slightly warm in nature; Enter liver, kidney channel. Nourishing the blood and yin; Relax bowel; Preventing malaria; Dispel the wind; Removing toxic substances.Main deficiency of blood Light-headedness; Palpitaition; Insomnia; The soreness and weakness of waist and knees of the deficiency of liver-yin and kidney-yin; Poliosis; Tinnitus; Seminal emission; The dry constipation of intestines;Chronic malaria body void; Rubella itch; Sore carbuncle; Scrofula; Hemorrhoid.
Stem of noble dendrobium taste is sweet, cold nature, returns stomach, kidney channel. Reinforcing stomach reg fluid is nourishing Yin and clearing heat. For pyreticosis Tianjin wound, dry polydipsia, stomachAsthenic yin, food is less than to be vomitted, and abnormal heat is not moved back after being ill, fire excess from yin deficiency, hectic fever due to yin labor heat, order is secretly not clear, and muscles and bones is withered soft.
Poria cocos taste is sweet, light, and property is flat; The thoughts of returning home, lung, spleen, kidney channel. Clearing damp and promoting diuresis, invigorating the spleen, Ning Xin. For oedema oliguria,Phlegm and retained fluid is dizzy throbs with fear, and insufficiency of the spleen food is few, and have loose bowels in loose stool, confused and worried, palpitation with fear insomnia.
Compared with prior art, health kidney tonifying okra wine formula of the present invention is reasonable, and enriching yin is if the composition such as Poria cocos, Chinese yam is with strongSun, as the composition such as saline cistanche, tribulus terrestris combines, brings out the best in each other. By oxidative decoloration and macroreticular resin decolouring, make the color of wineMore limpid, attractive in appearance. Effect of the present invention can be further strengthened in the interpolation of okra, tribulus terrestris and wolfberry fruit extract. All medicinesCoordinate, whole reasonable recipe, rigorous, obviously tonifying kidney-yin, invigorating kidney yang, impels the autonomous production of sperm of kidney, makes vital essence full,Vigour is continuous. There is effect of good nourishing health and kidney tonifying.
In order to understand better and to implement, describe the present invention below in detail.
Detailed description of the invention
Embodiment 1: the preparation of Abelmoschus Esculentus Linn extract
After putting into 3kg90~100 DEG C hot water 3~5min after tender 1kg okra pod is cleaned, take out, be cooled to room temperature, add 5In the water of times weight, wear into slurries shape, after the centrifugal 1~3min of 3000~5000r/min, discard insoluble matter, supernatant is the described yellow autumnCertain herbaceous plants with big flowers extract.
Embodiment 2: the preparation of Abelmoschus Esculentus Linn extract
After putting into 8kg90~100 DEG C hot water 3~5min after tender 2kg okra pod is cleaned, take out, be cooled to room temperature, add 5In the water of times weight, wear into slurries shape, after the centrifugal 1~3min of 3000~5000r/min, discard insoluble matter, supernatant is the described yellow autumnCertain herbaceous plants with big flowers extract.
Embodiment 3: the preparation of Abelmoschus Esculentus Linn extract
After putting into 1kg90~100 DEG C hot water 3~5min after tender 0.5kg okra pod is cleaned, take out, be cooled to room temperature, addIn the water of 5 times of weight, wear into slurries shape, after the centrifugal 1~3min of 3000~5000r/min, discard insoluble matter, supernatant is described HuangGumbo extract.
Embodiment 4: the preparation of wolfberry fruit extract
The preparation of wolfberry fruit extract of the present invention comprises the following steps:
(1). matrimony vine is shone to dry grinding, and mixing that the benzinum that goes 1kg matrimony vine powder to join 5kg is 1: 1 with acetone volume ratio is moltenIn liquid, backflow 3h, discards solvent after being cooled to room temperature,
(2). the last residue of step (1) is added to the 3h that refluxes in the ethanol of 3 times of weight, discard solvent after being cooled to room temperature,
(3). the last residue of step (2) is added in 10 times of weight water, add sodium hydrate regulator solution pH value to 9, super at 75 DEG CSound extracts 2h, extracts altogether 2 times, merges extract extract, adds ethanol to make its precipitation,
(4). precipitation is leached, add water and after redissolution, add sodium hydrate regulator solution pH value to 8.0 completely, add 1/20 volumeThe mass fraction hydrogenperoxide steam generator that is 30%, stir 0.5h at 60 DEG C, adding ethanol after cooling precipitates again, by dry gained precipitationDryly obtain described wolfberry fruit extract.
Embodiment 5: the preparation of wolfberry fruit extract
The preparation of wolfberry fruit extract of the present invention comprises the following steps:
(1). matrimony vine is shone to dry grinding, go 2kg matrimony vine powder to join the benzinum and mixing that acetone volume ratio is 1: 1 of 10kgIn solution, backflow 1h, discards solvent after being cooled to room temperature,
(2). the last residue of step (1) is added to the 1h that refluxes in the ethanol of 3 times of weight, discard solvent after being cooled to room temperature,
(3). the last residue of step (2) is added in 10 times of weight water, add sodium hydrate regulator solution pH value to 10, at 80 DEG CUltrasonic extraction 1h, extracts 2 times altogether, merges extract extract, adds ethanol to make its precipitation,
(4). precipitation is leached, add water and after redissolution, add sodium hydrate regulator solution pH value to 8.0 completely, add 1/20 volumeThe mass fraction hydrogenperoxide steam generator that is 30%, stir 40min at 60 DEG C, adding ethanol after cooling precipitates again, and gained is precipitatedBe drying to obtain described wolfberry fruit extract.
Embodiment 6: the preparation of wolfberry fruit extract
The preparation of wolfberry fruit extract of the present invention comprises the following steps:
(1). matrimony vine is shone to dry grinding, go 3kg matrimony vine powder to join the benzinum and mixing that acetone volume ratio is 1: 1 of 15kgIn solution, backflow 0.5h, discards solvent after being cooled to room temperature,
(2). the last residue of step (1) is added to the 2h that refluxes in the ethanol of 3 times of weight, discard solvent after being cooled to room temperature,
(3). the last residue of step (2) is added in 10 times of weight water, add sodium hydrate regulator solution pH value to 11, at 90 DEG CUltrasonic extraction 30min, extracts 2 times altogether, merges extract extract, adds ethanol to make its precipitation,
(4). precipitation is leached, add water and after redissolution, add sodium hydrate regulator solution pH value to 8.0 completely, add 1/20 volumeThe mass fraction hydrogenperoxide steam generator that is 30%, stir 1h at 60 DEG C, adding ethanol after cooling precipitates again, by dry gained precipitationObtain described wolfberry fruit extract.
Embodiment 7: the preparation of tribulus terrestris extraction
The preparation of tribulus terrestris extraction of the present invention comprises the following steps:
(1). 1kg tribulus terrestris fruit is dried to rear pulverizing, adds the 2h that refluxes in the ethanolic solution of 50% (v/v) of 5kg, let cool toRoom temperature, gets supernatant after centrifugal;
(2). the supernatant that step (1) the is made HPD300 large pore resin absorption column of flowing through adsorbs, and uses successively 3 after upper propThe ethanolic solution of 30% (v/v) of the water of bed volume and 3 bed volumes washes away color, then uses the ethanolic solution of 60% (v/v)Wash-out, collects eluent, is dried to medicinal extract, to obtain final product.
Embodiment 8: the preparation of tribulus terrestris extraction
The preparation of tribulus terrestris extraction of the present invention comprises the following steps:
(1). 2kg tribulus terrestris fruit is dried to rear pulverizing, add the 1.5h that refluxes in the ethanolic solution of 70% (v/v) of 10kg, let coolTo room temperature, get supernatant after centrifugal;
(2). the supernatant that step (1) the is made HPD300 large pore resin absorption column of flowing through adsorbs, and uses successively 4 after upper propThe ethanolic solution of 20% (v/v) of the water of bed volume and 4 bed volumes washes away color, then uses the ethanolic solution of 80% (v/v)Wash-out, collects eluent, is dried to medicinal extract, to obtain final product.
Embodiment 9: the preparation of tribulus terrestris extraction
The preparation of tribulus terrestris extraction of the present invention comprises the following steps:
(1). 3kg tribulus terrestris fruit is dried to rear pulverizing, add the 1h that refluxes in the ethanolic solution of 80% (v/v) of 15kg, let coolTo room temperature, get supernatant after centrifugal;
(2). the supernatant that step (1) the is made HPD300 large pore resin absorption column of flowing through adsorbs, and uses successively 5 after upper propThe ethanolic solution of 10% (v/v) of the water of bed volume and 5 bed volumes washes away color, then uses the ethanolic solution of 90% (v/v)Wash-out, collects eluent, is dried to medicinal extract, to obtain final product.
Embodiment 10: the preparation of health kidney tonifying okra wine
The preparation of health kidney tonifying okra wine of the present invention comprises the following steps:
(1). by Chinese yam 10g, saline cistanche 5g, Radix Angelicae Sinensis 3g, bark of eucommia 3g, Radix Astragali 3g, spina date seed 3g, fleece-flower root 5g, the root of herbaceous peony3g, stem of noble dendrobium 5g, Fructus Corni 3g, glutinous rehmannia 3g, Poria cocos 5g, rhizoma alismatis 3g, Radix Glycyrrhizae 10g clean, cut into slices after sterilizing, oven dry;
(2). the Abelmoschus Esculentus Linn extract that the section that step (1) is made and 3g embodiment 1 make, the matrimony vine that 10g embodiment 4 makesIt is that 50% 1000g is white that tribulus terrestris extraction, 1g propolis, the 20g honey that extract, 3g embodiment 7 make adds alcoholic strengthIn wine, stir propolis and honey are dissolved;
(3). the medicinal liquor that step (2) is made joins in the wine jar through sterilizing, and sealing stores 60 days at 15 DEG C.
Embodiment 11: the preparation of health kidney tonifying okra wine
The preparation of health kidney tonifying okra wine of the present invention comprises the following steps:
(1). by Chinese yam 20g, saline cistanche 15g, Radix Angelicae Sinensis 10g, bark of eucommia 10g, Radix Astragali 10g, spina date seed 10g, fleece-flower root 15g,Root of herbaceous peony 10g, stem of noble dendrobium 15g, Fructus Corni 10g, glutinous rehmannia 10g, Poria cocos 15g, rhizoma alismatis 10g, Radix Glycyrrhizae 20g clean, sterilizing, bakingSection after dry;
(2). the Abelmoschus Esculentus Linn extract that the section that step (1) is made and 10g embodiment 1 make, the matrimony vine that 20g embodiment 4 makesIt is 50% 2000g that tribulus terrestris extraction, 5g propolis, the 40g honey that extract, 10g embodiment 7 make adds alcoholic strengthIn white wine, stir propolis and honey are dissolved;
(3). the medicinal liquor that step (2) is made joins in the wine jar through sterilizing, and sealing stores 40 days at 25 DEG C.
Embodiment 12: the preparation of health kidney tonifying okra wine
The preparation of health kidney tonifying okra wine of the present invention comprises the following steps:
(1). by Chinese yam 12g, saline cistanche 8g, Radix Angelicae Sinensis 5g, bark of eucommia 5g, Radix Astragali 5g, spina date seed 5g, fleece-flower root 8g, the root of herbaceous peony5g, stem of noble dendrobium 8g, Fructus Corni 5g, glutinous rehmannia 5g, Poria cocos 8g, rhizoma alismatis 5g, Radix Glycyrrhizae 12g clean, cut into slices after sterilizing, oven dry;
(2). the Abelmoschus Esculentus Linn extract that the section that step (1) is made and 5g embodiment 2 make, the matrimony vine that 12g embodiment 5 makesTribulus terrestris extraction, 2g propolis, the 25g honey that extract, 5g embodiment 8 make add 1200g alcoholic strength be 40% whiteIn wine, stir propolis and honey dissolved:
(3). the medicinal liquor that step (2) is made joins in the wine jar through sterilizing, and sealing stores 50 days at 20 DEG C.
Embodiment 13: the preparation of health kidney tonifying okra wine
The preparation of health kidney tonifying okra wine of the present invention comprises the following steps:
(1). by Chinese yam 18g, saline cistanche 12g, Radix Angelicae Sinensis 8g, bark of eucommia 8g, Radix Astragali 8g, spina date seed 8g, fleece-flower root 12g, whiteChinese herbaceous peony 8g, stem of noble dendrobium 12g, Fructus Corni 8g, glutinous rehmannia 8g, Poria cocos 12g, rhizoma alismatis 8g, Radix Glycyrrhizae 18g clean, cut after sterilizing, oven drySheet;
(2). the Abelmoschus Esculentus Linn extract that the section that step (1) is made and 8g embodiment 2 make, the matrimony vine that 18g embodiment 5 makesIt is that 60% 1800g is white that tribulus terrestris extraction, 4g propolis, the 35g honey that extract, 8g embodiment 8 make adds alcoholic strengthIn wine, stir propolis and honey are dissolved;
(3). the medicinal liquor that step (2) is made joins in the wine jar through sterilizing, and sealing stores 50 days at 20 DEG C.
Embodiment 14: the preparation of health kidney tonifying okra wine
The preparation of health kidney tonifying okra wine of the present invention comprises the following steps:
(1). by Chinese yam 15g, saline cistanche 10g, Radix Angelicae Sinensis 6g, bark of eucommia 6g, Radix Astragali 6g, spina date seed 6g, fleece-flower root 10g, whiteChinese herbaceous peony 6g, stem of noble dendrobium 10g, Fructus Corni 6g, glutinous rehmannia 6g, Poria cocos 10g, rhizoma alismatis 6g, Radix Glycyrrhizae 15g clean, cut after sterilizing, oven drySheet;
(2). the Abelmoschus Esculentus Linn extract that the section that step (1) is made and 6g embodiment 3 make, the matrimony vine that 15g embodiment 6 makesIt is that 50% 1500g is white that tribulus terrestris extraction, 3g propolis, the 30g honey that extract, 6g embodiment 9 make adds alcoholic strengthIn wine, stir propolis and honey are dissolved;
(3). the medicinal liquor that step (2) is made joins in the wine jar through sterilizing, and sealing stores 50 days at 20 DEG C.
Embodiment 15 (comparative example): the preparation of health kidney tonifying okra wine
The preparation of health kidney tonifying okra wine of the present invention comprises the following steps:
(1). by Chinese yam 15g, saline cistanche 10g, Radix Angelicae Sinensis 6g, bark of eucommia 6g, Radix Astragali 6g, spina date seed 6g, fleece-flower root 10g, whiteChinese herbaceous peony 6g, stem of noble dendrobium 10g, Fructus Corni 6g, glutinous rehmannia 6g, Poria cocos 10g, rhizoma alismatis 6g, Radix Glycyrrhizae 15g clean, cut after sterilizing, oven drySheet;
(2). it is, in 50% 1500g white wine, to stir that the section that step (1) is made and 3g propolis, 30g honey add alcoholic strengthPropolis and honey are dissolved;
(3). the medicinal liquor that step (2) is made joins in the wine jar through sterilizing, and sealing stores 50 days at 20 DEG C.
Embodiment 16: the experimental study of the present composition aspect antifatigue
Get 160 the male SPF level of health mouse, body weight is 18~22g, and the conventional illumination of mouse, drinking-water are raised in 25 DEG C of environmentSupport. Mouse is equally divided into 8 batchings at random, 20 every group, carries out Loaned swimming test. 1st~6 groups give respectively embodiment10~15 health kidney tonifying okra wines that make, the 7th group gives commercially available product health kidney-tonifying wine, and the 8th group gives physiological saline. OftenDay gavage 1 time, gavage amount be in mouse body weight 1%, gastric infusion 30d continuously. After last administration 30min, bear a heavy burdenSwimming test. Swimming trunk depth of water 30cm, water temperature is 25 ± 0.5 DEG C, mouse tail root weighing load is the lead of Mouse Weight 3.5%Skin, records mouse and starts to submerge the time that 10s can not emerge in water to head from swimming, as mice burden swimming timeBetween. Result is as shown in table 1:
Impact (min) > of < table 1 the present invention on the mice burden swimming time
Note: * * is and reference substance and commercially available product comparison, p < 0.05; * be and the comparison of physiological saline group, p < 0.05
As seen from the above table, the mouse endurance time that the embodiment of the present invention is 10~14 groups is obviously longer than comparative example group and commercially available product group,And comparative example group and commercially available product group are also obviously longer than physiological saline group, all there were significant differences. Can draw and add okra extractionThe health preserving wine of thing, wolfberry fruit extract and tribulus terrestris extraction has extraordinary health, antifatigue effect.
Embodiment 17: the present composition is at the experimental study improving aspect sexual function
Pick out 80 of male mices normally healthy and that property vigor is similar by preliminary experiment, 240 of female mices, body weight is18~22g, is divided into 8 groups at random by male mice, and 10 every group, 1st~6 groups give respectively the health that embodiment 10~15 makesKidney tonifying okra wine, the 7th group gives commercially available product health kidney-tonifying wine, and the 8th group gives physiological saline. Every day gavage 1 time, gavageAmount is 1% of body weight in mouse, gastric infusion 5d continuously. After last administration 1h, in 1: 3 ratio, male mouse and female mouse are mated,Record the mating number of times in each group of male mouse mating incubation period (from mating the time of the female mouse of mating for the first time) and 2h. Result is as table 2Shown in.
The affect > of < table 2 the present invention on male mice vigor
Note: * * is and reference substance and commercially available product comparison, p < 0.05; * be and the comparison of physiological saline group, p < 0.05
As seen from the above table, show that the health preserving wine that has added Abelmoschus Esculentus Linn extract, wolfberry fruit extract and tribulus terrestris extraction has veryGood effect.
Embodiment 18: model case
Week certain, man, 49 years old, conscious weak all over, breathe hard, night sweat. Due to tcm diagnosis thinks and suffers from a deficiency of the kidney. Suggestion is drunkHealth kidney tonifying okra wine of the present invention is taken good care of. Respectively drink 1 time after ante cibum and supper morning every day, each 10 milliliters. Through 5After within individual month, drinking, above-mentioned symptom disappears.
5 certain, female 40 years old, has pain in low back and legs, insomnia, dreaminess, irregular menstruation symptom, 2015 3 for many years alwaysThe moon starts to drink health kidney tonifying okra wine of the present invention and takes good care of. Respectively drink 1 time after ante cibum and supper morning every day, each20 milliliters. After 4 months drink, above-mentioned symptom disappears, so far without recurrence.
3. Zheng, man, 65 years old, easily palpitation and short breath, was short of physical strength, manual labor lethargy. Be for suffering from a deficiency of the kidney through tcm diagnosis.Rise in January, 2015 and start to drink health kidney tonifying okra wine of the present invention and take good care of. Respectively drink 1 after ante cibum and supper morning every dayInferior, each 15 milliliters. After 6 months, muscle power is restored with energy, conscious strong.
The present invention is not limited to above-mentioned embodiment, if various changes of the present invention or distortion are not departed to spirit of the present inventionAnd scope, if within these changes and distortion belong to claim of the present invention and equivalent technologies scope, the present invention is also intended toComprise these changes and distortion.

Claims (9)

1. a health kidney tonifying okra wine, is characterized in that being made up of the component of following weight portion: 3~10 parts of Abelmoschus Esculentus Linn extracts,10~20 parts of wolfberry fruit extracts, 3~10 parts of tribulus terrestris extractions, 1~5 part of propolis, 10~20 parts of Chinese yams, saline cistanche 5~15Part, 3~10 parts of Radix Angelicae Sinensis, 3~10 parts of the barks of eucommia, 3~10 parts of the Radixs Astragali, 3~10 parts of spina date seeds, 5~15 parts of the fleece-flowers root, the root of herbaceous peony3~10 parts, 5~15 parts of the stems of noble dendrobium, 3~10 parts of Fructus Cornis, 3~10 parts of glutinous rehmannia, 5~15 parts, Poria cocos, 3~10 parts of rhizoma alismatis,10~20 parts, Radix Glycyrrhizae, 20~40 parts of honey, 1000~2000 parts of white wine.
2. health kidney tonifying okra wine according to claim 1, is characterized in that being made up of the component of following weight portion: Huang Qiu5~8 parts of certain herbaceous plants with big flowers extracts, 12~18 parts of wolfberry fruit extracts, 5~8 parts of tribulus terrestris extractions, 2~4 parts of propolis, Chinese yam 12~18Part, 8~12 parts of saline cistanches, 5~8 parts of Radix Angelicae Sinensis, 5~8 parts of the barks of eucommia, 5~8 parts of the Radixs Astragali, 5~8 parts of spina date seeds, the fleece-flower root8~12 parts, 5~8 parts of the root of herbaceous peonys, 8~12 parts of the stems of noble dendrobium, 5~8 parts of Fructus Cornis, 5~8 parts of glutinous rehmannia, 8~12 parts, Poria cocos, rhizoma alismatis5~8 parts, 12~18 parts, Radix Glycyrrhizae, 25~35 parts of honey, 1200~1800 parts of white wine.
3. health kidney tonifying okra wine according to claim 2, is characterized in that being made up of the component of following weight portion: Huang Qiu6 parts of certain herbaceous plants with big flowers extracts, 15 parts of wolfberry fruit extracts, 6 parts of tribulus terrestris extractions, 3 parts of propolis, 15 parts of Chinese yams, saline cistanche10 parts, 6 parts of Radix Angelicae Sinensis, 6 parts of the barks of eucommia, 6 parts of the Radixs Astragali, 6 parts of spina date seeds, 10 parts of the fleece-flowers root, 6 parts of the root of herbaceous peonys, the stem of noble dendrobium10 parts, 6 parts of Fructus Cornis, 6 parts of glutinous rehmannia, 10 parts, Poria cocos, 6 parts of rhizoma alismatis, 15 parts, Radix Glycyrrhizae, 30 parts of honey, white wine1500 parts.
4. according to the health kidney tonifying okra wine described in claim 1~3 any one, it is characterized in that: the alcoholic strength of described white wineBe 40~60%.
5. a preparation method for health kidney tonifying okra wine, is characterized in that comprising the following steps:
(1). by weight portion described in claim 1~3 any one, by Chinese yam, saline cistanche, Radix Angelicae Sinensis, the bark of eucommia, spina date seed, whatThe tuber of multiflower knotweed, the root of herbaceous peony, the stem of noble dendrobium, Fructus Corni, glutinous rehmannia, Poria cocos, rhizoma alismatis and Radix Glycyrrhizae are cleaned, cut into slices after sterilizing, oven dry;
(2). section and Abelmoschus Esculentus Linn extract, wolfberry fruit extract, tribulus terrestris extraction, propolis, honey that step (1) is made addEnter in white wine, stir propolis and honey are dissolved;
(3). the medicinal liquor that step (2) is made joins in the wine jar through sterilizing, and sealing stores 40~60 days at 15~25 DEG C.
6. the method for health kidney tonifying okra wine according to claim 5, is characterized in that the preparation of described Abelmoschus Esculentus Linn extractMethod is: after putting into 90~100 DEG C of hot water 3~5min after tender okra pod is cleaned, take out, be cooled to room temperature, add 5In the water of times weight, wear into slurries shape, after the centrifugal 1~3min of 3000~5000r/min, discard insoluble matter, described in supernatant isAbelmoschus Esculentus Linn extract.
7. the method for health kidney tonifying okra wine according to claim 5, is characterized in that the preparation bag of described wolfberry fruit extractDraw together following steps:
(1). matrimony vine is shone to dry grinding, matrimony vine powder is added to the 0.5~3h that refluxes in the extract a of 5 times of weight, abandon after being cooled to room temperatureDesolventizing,
(2). the last residue of step (1) is added to the 1~3h that refluxes in the ethanol of 3 times of weight, discard solvent after being cooled to room temperature,
(3). the last residue of step (2) is added in 10 times of weight water, add sodium hydrate regulator solution pH value to 9~11,75~90 DEG CLower ultrasonic extraction 30min~2h, extracts 2 times altogether, merges extract extract, adds ethanol to make its precipitation,
(4). precipitation is leached, add water and after redissolution, add sodium hydrate regulator solution pH value to 8.0 completely, add 1/20 volumeThe mass fraction hydrogenperoxide steam generator that is 30%, stir 0.5~1h at 60 DEG C, adding ethanol after cooling precipitates again, and gained is heavyShallow lake is drying to obtain described wolfberry fruit extract;
Wherein said extract a is the mixed solution that benzinum and acetone volume ratio are 1: 1.
8. the method for health kidney tonifying okra wine according to claim 5, is characterized in that the preparation of described tribulus terrestris extractionComprise the steps:
(1). tribulus terrestris fruit is dried to rear pulverizing, in the ethanolic solution that the percent by volume that adds 5 times of weight is 50~80%, reflux1~2h, lets cool to room temperature, gets supernatant after centrifugal;
(2). the supernatant that step (1) the is made large pore resin absorption column of flowing through adsorbs, and uses successively 3~5 post bed bodies after upper propThe percent by volume of long-pending water and 3~5 bed volumes is that 10~30% ethanolic solution washes away color, then uses volume percentageThan the ethanolic solution wash-out that is 60~90%, collect eluent, be dried to medicinal extract, to obtain final product.
9. the method for health kidney tonifying okra wine according to claim 9, is characterized in that: described macroporous absorbent resin isHPD300 macroreticular resin.
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WO2017143798A1 (en) * 2016-02-22 2017-08-31 彭海英 Health preserving and kidney tonifying okra wine and preparation method therefor
CN107841432A (en) * 2017-12-12 2018-03-27 合肥市绿之林农业开发有限公司 A kind of okra health liquor of tonifying kidney and strengthening yang and preparation method thereof

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