CN108524814A - A kind of Chinese medicine composition and preparation method thereof for reducing blood glucose - Google Patents

Abstract

The invention discloses a kind of Chinese medicine composition and preparation method thereof for reducing blood glucose, which is made of the following raw material:4 kinds of mineral matter elements such as 6 kinds of Chinese medicines and Cr-enriched yeast such as 24 kinds of extracts such as Ba Naba extracts, fenugreek extract, Astragalus Root P.E, mulberry-leaf extract and ginseng, spirulina.After the essential trace elements of the human body is added in pharmaceutical composition of the present invention, any type clinically acceptable Suitable pharmaceutical preparations are prepared into according to this field conventional formulation method.It is good hypoglycemic that Pharmacological test results show that pharmaceutical composition of the present invention has the function of, preparation method science is simple, without any side effects, is suitble to all age group crowd, while conditioning engine body reduces blood glucose, has good effect for reducing blood fat.

Description

A kind of Chinese medicine composition and preparation method thereof for reducing blood glucose

Technical field

More particularly, to a kind of with hypoglycemic effect, the Chinese medicine composition of control diabetic complication and its preparation side Method belongs to medicine, food, field of health care products.

Background technology

Hyperglycemia refers to that the blood glucose of people is higher than normal level, equal to each section of human body if this situation persistently exists It is harmful.There are many reason of causing hyperglycemia, diabetes be by inherent cause, immunologic function disorder, microorganism infection and its toxin, The effects that free radical toxin, mental element, leads to hypoinsulinism, insulin resistance etc. and sugar, the albumen of initiation in body A series of metabolism disturbance syndromes such as matter, fat, water and electrolyte.But with the continuous improvement of modern life level, mostly Number factor is often that bad life habits and environment, present young man are mostly delithted with fast food, does not like vegetables and fruit, long Long eating habit may lead to high blood glucose;In addition, with the pollution of environment, negative oxygen ion content in air is caused to reduce sharply, The negative oxygen ion of human intake is insufficient, this is also a major reason for leading to hyperglycemia.

The clinical manifestation of diabetes is hyperglycemia and glycosuria.There is more foods, more drinks, diuresis, dry and general weakness in patient Etc. symptoms, belong to the scope that Chinese medicine is quenched one's thirst.Diabetes and cancer, cardiovascular and cerebrovascular disease is same is considered as worldwide three big diseases.

The world today, with the acceleration of rapid development of economy and process of industrialization, human health faces non-infectious disease The threat of disease is increasingly being, and diabetes prevalence and diabetic's quantity steeply rise.Diabetes and its complication are to people Class health and social development bring serious burden.

The pathogenic process of diabetes complexity makes the method that the mankind not yet find radical cure so far, this means that patient needs end Body receives treatment, but regrettably, even in developed country, also has about 2/3 patient that cannot effectively manage.Long-term blood glucose Control bad diabetic occur together various complication the life and quality of life of patient are threatened it is very big, to family and Patient individual brings heavy financial burden.

It is counted according to International Diabetes Federation, has a diabetic 3.31 hundred million in the whole world in 2016, and current patient of diabetes Person, according to current growth rate, estimates that the year two thousand thirty whole world will have 600,000,000 people to suffer from diabetes up to 3.85 hundred million.According to world health Tissue discloses, and the whole world just has 1 people to die of diabetes for every 10 seconds, just has within every 30 seconds 1 people because of diabetes amputation, blinds in addition, heart and brain The complication such as blood vessel, diabetes have become serious public health problem.Diabetes endanger human life's safety, thus cause Psychological problems, social concern also becomes increasingly conspicuous.Therefore, relevant expert points out, " diabetes are no longer that diabetic individual asks Topic, even more a global problem.”

Hypoglycemic medicine is clinically still based on Western medicine at present, but because that there are hypoglycemia and gastrointestinal reactions etc. is many bad anti-for it It answers, therefore the target for finding high-efficiency low-toxicity reduction hypoglycemic medicament is urgently realized.

Recent study find, Chinese medicine hypoglycemic effect is mildly lasting, and adverse reaction is few, the mechanism of action have manifold effect, Multidigit point and it is multi-functional the features such as, sugar tolerance and the occurrence and development that diabetic complication is effectively relieved can be improved, be develop drop One new approach of blood glucose new drug.

TCM Treatment of Diabetes has thousands of years of history, recorded in medical book a large amount for the treatment of diabetes Chinese medicine and its Compound preparation, thus from Chinese traditional herbs research and develop Novel antidiabetic Chinese medicine preparation have great importance with it is wide Foreground.Currently, being flooded with all kinds of hypoglycemic products in the market, but the seldom of real effect can be played, therefore provided a kind of The drug that hypoglycemic effect can really be played is critically important.

There is the present invention pharmaceutical composition of effect of lowering blood sugar extracted from a variety of natural plants rich in hypoglycemic control blood glucose Active ingredient, the research to hyperglycaemic conditions mechanism and its principle of reatment based on traditional Chinese medicine, at the same according to pharmaceutical research at Fruit controls blood glucose from source, meets international newest healthy trend.

The present invention has the function of the pharmaceutical composition composition formula of effect of lowering blood sugar with more hypoglycemic, control blood glucose, hyperglycemia Crowd is used for a long time its control hypoglycemic effect and becomes apparent from, and hypoglycemic effect is more reliable.

The present invention has the pharmaceutical composition of hypoglycemic effect, belongs to the Chinese medical extract of integration of drinking and medicinal herbs, secondary without any poison Effect can adjust blood sugar level steadily, reduce hyperglycemia, and low hyperglycemia will not be caused to react, and be suitble to patient of diabetes Person takes for a long time, not will produce dependence and drug resistance.

Invention content

The purpose of the present invention is to solve deficiencies existing for above-mentioned technical problem, provide a kind of for reducing in blood glucose Drug composition and preparation method thereof, the composition have drawn from extensive common Chinese material or its extract, and add micro Element adjusts the acid-base balance of human body, improves the immunity of human body, to reach reduction blood glucose, in the medical history for reducing blood glucose It is upper to become new breakthrough point.

The Ultramicro-powder and 4 kinds of micro members of the present invention innovatively extract of the pure natural Chinese herbal medicine of 24 tastes, 6 kinds of Chinese herbal medicines Element carries out ideally organic assembling, is equipped with advanced technological process, using up to standard selected, cleaning, purification, tanning extraction, dusting After synthesis, with new technologies such as dry, wet fermentation, Ultramicro-powder, vibration of ultrasonic wave, reach in conjunction with scientific compatibility naturally, environmental protection, peace Entirely, the effective purpose of health.

In view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to provide a kind of pharmaceutical composition with hypoglycemic effect Object;It is a further object to provide the preparation methods of the pharmaceutical composition.

To achieve the goals above, the present invention is to realize by the following technical solutions：

A kind of Chinese medicine composition for reducing blood pressure includes the substance of following parts by weight:

60-100 parts of banaba leaf extract, 60-100 parts of faenum graecum seed extract, 60-100 parts of money willow extract, hypoglycemic grass 60-100 parts of extract, 60-100 parts of guava leaf extract, 30-60 parts of garlic P.E, 60-130 parts of burdock extract, 40-90 parts of Corn silk P.E, 30-90 parts of Shorthorned Epimedium P.E, 60-120 parts of Astragalus Root P.E, Cortex Lycii extract 30-60 Part, 30-60 parts of mulberry bark extract, 60-120 parts of mulberry-leaf extract, 30-60 parts of Fructus lycii P.E, kudzu root extract 30-60 Part, 60-120 parts of Bitter Melon P.E, 60-120 parts of cinnamomum cassia extract, 20-30 parts of Salvia root P.E, 30-60 parts of Rhizoma Polygonati extract, 20-40 parts of Semen Coicis extract, 60-100 parts of Radix Trichosanthis extract, 30-60 parts of Rhizoma Polygonati Odorati extract, cornel extractive 60-120 Part, 30-60 parts of anemarrhena asphodefoides extract;30-80 parts of ginseng, 60-100 parts of spirulina, 60-100 parts of Ramulus euonymi, 15-45 parts of the coptis, life 20-40 parts of glutinous rehmannia, 30-60 parts of Schisandra chinensis;2-6 parts of Cr-enriched yeast, 2-4 parts of Se-enriched yeast, 1-3 parts of Zinc-rich saccharomyces cerevisiae, magnesium stearate 2-6 parts.

The present invention's this is for reducing the Chinese medicine composition preparation method of blood pressure：

Step 1: by 30-80 parts of ginseng, 60-100 parts of spirulina, 60-100 parts of Ramulus euonymi, 15-45 parts of the coptis, radix rehmanniae recen 20- 40 parts, 30-60 parts of Schisandra chinensis, cleaning selected with single product, air-dry purification, are respectively crushed into coarse powder, the granularity of coarse powder is 24-50 Mesh is uniformly mixed, it is spare that coarse powder mixture is made;It is divided into three parts;

Step 2: first part of coarse powder mixture is put into sealing porcelain, temperature is under 25-30 degree, spontaneous fermentation 5-7 days, fermentation After the completion, it is cleaned and is dried with clear water, obtain dry fermentation coarse powder mixture；Second part of coarse powder mixture is eluted with pure water, The cellulase of the 2-5% of second part of coarse powder total weight of the mixture is added, carries out vibration of ultrasonic wave 20-30 minutes, is sufficiently stirred, Then fermentation being sealed to coarse powder mixture, temperature is fermented 1-3 days under 25-30 degree, after fermentation, 6-8 times clear of progress It washes, squeeze, dry, obtain wet fermentation coarse powder mixture；Third part coarse powder mixture carries out naturally dry；First part, second Part and third part mixture are mixed, and mixing coarse powder mixture is obtained；Mixing coarse powder mixture is ground, ultra micro is obtained Powder mixture, the granularity of ultra micro powder mixture is at 0.1 μm -10 μm;

It is impregnated 60 minutes Step 3: small molecule energy water is added in the ultra micro powder mixture that step 2 is obtained, is made to impregnate and mix Material is closed, wherein the weight for the small molecule energy water being added and ginseng, spirulina, Ramulus euonymi, the coptis, radix rehmanniae recen, Schisandra chinensis coarse powder The ratio between total weight of mixture is 6:1;

Step 4: the mixture that step 3 obtains is placed in Multifunctional Chinese medicine extraction kettle, open multi-functional extraction kettle power supply into Row is heated to 100 DEG C, keep at this temperature constant temperature lift 1 hour, produce the first extraction mixture, then filter, obtain the No. one time extracting solution is spare;

Step 5: small molecule energy water, the weight of the weight and coarse powder mixture of the small molecule energy water of addition are added into filter residue The ratio between amount is 2:1, heating extraction, heating temperature is 100 DEG C, and extraction time is 1 hour, and second of extracting solution is obtained by filtration;

Step 6: the merging of extracting solution twice is placed in triple effect vacuum high energy evaporation concentrator, be decompressed to relative pressure be- 0.07MPa is heated to 80 DEG C, and extracting solution is condensed into the medicinal extract that proportion is 1.30, is then dried, obtains at 45-50 DEG C To dry extract;

Step 7: after dry extract is broken into 100-150 targeted fine powders, 60-100 parts of banaba leaf extract, faenum graecum is added 60-100 parts of seed extract, 60-100 parts of money willow extract, 60-100 parts of hypoglycemic grass extract, guava leaf extract 60- 100 parts, 30-60 parts of garlic P.E, 60-130 parts of burdock extract, 40-90 parts of Corn silk P.E, Shorthorned Epimedium P.E 30-90 parts, 60-120 parts of Astragalus Root P.E, 30-60 parts of Cortex Lycii extract, 30-60 parts of mulberry bark extract, mulberry-leaf extract 60-120 parts, 30-60 parts of Fructus lycii P.E, 30-60 parts of kudzu root extract, 60-120 parts of Bitter Melon P.E, cinnamomum cassia extract 60-120 parts, 20-30 parts of Salvia root P.E, 30-60 parts of Rhizoma Polygonati extract, 20-40 parts of Semen Coicis extract, Radix Trichosanthis extract 60-100 parts, 30-60 parts of Rhizoma Polygonati Odorati extract, 60-120 parts of cornel extractive, 30-60 parts of anemarrhena asphodefoides extract；It adds chromium-rich 2-6 parts of yeast, 2-4 parts of Se-enriched yeast, 1-3 parts of Zinc-rich saccharomyces cerevisiae, 2-6 parts of magnesium stearate are packed into gelatin hard after mixing Capsule to get:The present invention of every 0.45 gram of weight.

Number is parts by weight in wherein all steps.

The unavailable tap water of the useful water of present composition institute, mineral water, distilled water use, and process is all using small Molecular energy water.

Wherein in the present composition is pure natural plant extract, no incompatibility.

Wherein in step 1, the granularity of coarse powder is 24-50 mesh, cannot be too thin, can not be too thick, is in order to subsequently dry, wet The technique of fermentation, medicinal ingredient that can utmostly in extraction of substance.

After first part of coarse powder mixture dry fermentation wherein in step 2, it can be maximally maintained Chinese medicine nutritional ingredient, And the alcoholic degree of final products can be improved.

Second part of coarse powder mixture wherein in step 2, which impregnates, carries out vibration of ultrasonic wave 20-30 minutes, is in order to will be thick The cell wall of powder mixture is broken, it is allowed to discharge the gamma aminobutyric acid of cell interior and the pure grade substances of plant.

The cellulase of the 2-5% of overstriking powder mixture total weight wherein in step 2 is in order to which cellulase can be broken The structure of coarse powder mixture cell wall, destroys the structure of cell wall, and intracellular ingredient is made to dissolve, to reach the mesh of extraction 's.

The granularity of this 4 taste Chinese herbal ultra-fine powder mixture after being ground wherein in step 2 is at 0.1 μm -10 μm, due to people This 6 taste Chinese medicine of ginseng, spirulina, Ramulus euonymi, the coptis, radix rehmanniae recen, Schisandra chinensis is hard in heterogeneity, and general be crushed can not break completely The cell wall of this 6 taste Chinese medicine, because the dissolution of effective medicinal component needs guiding through several or even dozens of cell wall in cell, and And quite a few Cell Component can not possibly pass through cell wall, this part that can only waste, therefore can not make intracellular Active ingredient all fully release, the present invention reaches Ultramicro-powder by way of grinding, makes intracellular effective Ingredient all fully releases, to improve the bioavilability of medicinal material, and this Chinese medicine mixed-powder granularity after grinding It is very tiny, it is more advantageous to human body and drug is absorbed and utilized.

Extraction twice has been carried out to mixture in step 4 and five, has been more preferably more to extract medical substance.

Dry extract is broken into 100-150 targeted fine powders wherein in step 7, is because fine powder has reached ultra micro Powder is not only conducive to the absorption of human body, and whole drug effects in the present invention is made to bring into play, and, the mouthfeel of user can be improved, no Feel the pain of medication.

The present invention select banaba leaf extract, faenum graecum seed extract, money willow extract, hypoglycemic grass extract, kind Pomegranate leaf extract, garlic P.E, burdock extract, Corn silk P.E, Shorthorned Epimedium P.E, Astragalus Root P.E, Bone bark extract, mulberry bark extract, mulberry-leaf extract, wolfberry fruit extract, kudzu root extract, Bitter Melon P.E, Chinese cassia tree extraction Object, Rhizoma Polygonati extract, Semen Coicis extract, Radix Trichosanthis extract, Rhizoma Polygonati Odorati extract, cornel extractive, is known Salvia root P.E 6 kinds of Chinese herbal medicines and the richness such as 24 kinds of extracts such as female extract and ginseng, spirulina, Ramulus euonymi, the coptis, radix rehmanniae recen, Schisandra chinensis The mineral trace element combination needed by human of 4 kinds of selenium yeast, Cr-enriched yeast, Zinc-rich saccharomyces cerevisiae, magnesium stearate etc. is prepared, respectively Active constituent in kind drug generates synergistic effect, mutually promotes improvement insulin secretion, increases insulin sensitivity, influence pancreas Island element receptor promotes the approach such as absorption and the decomposition of glycogen of glucose to play reduction blood glucose, control blood glucose, reduce complication Effect is repaired the vital organs of the human body, balanced human's negative and positive, is changed in addition under the common participation effect of supplement human body mineral matter trace element Kind metabolism in vivo, filling liver kidney is deficiency of the spleen-yin, to reach the effect for the treatment of diabetes.Formula uniqueness, obvious effect, according to diabetes The pathogenesis of people carries out specific aim adjusting, systemic conditioning, and help combines, and having significantly reduces blood glucose and control blood glucose Effect.It is the specific short of the treatment diabetes of a new generation that the present invention, which has the pharmaceutical composition of hypoglycemic effect,.

The present composition is using technology with banaba leaf extract, faenum graecum seed extract, money willow extract, hypoglycemic Careless extract, guava leaf extract, garlic P.E, burdock extract, Corn silk P.E, Shorthorned Epimedium P.E, Huang Stilbene extract, Cortex Lycii extract, mulberry bark extract, mulberry-leaf extract, wolfberry fruit extract, kudzu root extract, balsam pear extraction Object, cinnamomum cassia extract, Salvia root P.E, Rhizoma Polygonati extract, Semen Coicis extract, Radix Trichosanthis extract, Rhizoma Polygonati Odorati extract, mountain Zhu 24 kinds of Chinese herbal medicine extracts such as cornel extract, anemarrhena asphodefoides extract and ginseng, spirulina, Ramulus euonymi, the coptis, radix rehmanniae recen, Schisandra chinensis Deng 6 kinds of Chinese herbal medicines with advanced technological process, using up to standard selected, cleaning, purification, tanning extraction, after dusting synthesis, with hair 4 kinds of trace element combination scientific compatibilities such as ferment new technology addition Cr-enriched yeast, Se-enriched yeast, Zinc-rich saccharomyces cerevisiae and magnesium stearate reach Naturally, environmentally friendly, safety, the effective purpose of health.

Present composition formula is unique, obvious effect, the pathogenesis of foundation diabetes patient, the adjusting of progress specific aim, Systematicness conditioning, help combine, and hypoglycemic effect will significantly open the door of health to diabetic, are combined with scientific compatibility existing Generationization medicine has thoroughly broken hyperglycemia and has belonged to lifelong disease and can not cure, the mythology of rehabilitation.With its safety, surely Qualitative, generality, validity have brought Gospel, due contribution are made that for the healthy cause of the mankind, in medical row Its unique effect is played in industry.

The present invention is innovatively micro the extract of the pure natural Chinese herbal medicine of 24 tastes, the Ultramicro-powder of 6 kinds of Chinese herbal medicines and 4 kinds Element carries out ideally organic assembling, and according to the characteristic of these three components, is divided into three kinds of different preparation methods, further according to this The performance of medicinal ingredient contained by three groups of raw material, extracts medicinal ingredient with differently method respectively, in treatment diabetes Meanwhile it also functioning to liver protection, protecting kidney, the healthcare functions such as enrich blood；The present invention is not only at low cost, simple for process, without side-effects, Ke Yichang Phase takes, and reaches nature hypoglycemic, steady sugar, repairs pancreas islet, activation insulin secretion function, can gradually be withdrawn using the present invention Western medicine reduces the toxic side effect of Western medicine, effectively controls the injection of insulin dosage.

The application method and explanation of the present invention

[primary raw material] banaba leaf extract, faenum graecum seed extract, money willow extract, hypoglycemic grass extract, kind stone Pomegranate leaf extract, garlic P.E, burdock extract, Corn silk P.E, Shorthorned Epimedium P.E, Astragalus Root P.E, bone Bark extract, mulberry bark extract, mulberry-leaf extract, wolfberry fruit extract, kudzu root extract, Bitter Melon P.E, cinnamomum cassia extract, Salvia root P.E, Rhizoma Polygonati extract, Semen Coicis extract, Radix Trichosanthis extract, Rhizoma Polygonati Odorati extract, cornel extractive, burdock Seed extract, anemarrhena asphodefoides extract are primary raw material and ginseng, spirulina, Ramulus euonymi, the coptis, radix rehmanniae recen, Schisandra chinensis and minerals Micro- Cr-enriched yeast, Se-enriched yeast, Zinc-rich saccharomyces cerevisiae, magnesium stearate.

[primary efficacy] adjusts blood glucose, adjusts blood fat, prevents complication.

[suitable population] hyperglycemia, hyperlipemic patients take the patient of hypoglycemic Western medicine for a long time.

[instructions of taking and dosage] 0.5g capsules, three times per day, one time 2-3, warm water delivery service.

[points for attention] pregnant woman forbids taking, and forbids edible maror during medication and drinks.

The suitable crowd of the present invention

1. taking a variety of hypoglycemic medicines, the patient of long-term persistent high blood sugar.

2. refusing the patients with NIDDM of insulin therapy.

The diabetic of drink more than 3., more foods, diuresis and weight loss.

4. having generated insulin resistance, blood glucose is unstable, there is apparent complications.

5. refusing the patient of Western medicine toxic side effect treatment.

Six big advantages of the advantageous effect of the technology of the present invention during hypoglycemic

One, good effect, cure mechanism science, clear, treating both manifestation and root cause of disease.

1. can quick and stable blood glucose, it is quick.

2. diabetic complication can be improved, improve the quality of life of diabetic.

3. not only supplementing " insulin gene ", but also repair and create regeneration islet cells, ensures fundamentally rehabilitation.

Two, steady hypoglycemic while adjusting blood fat, protecting blood vessel and heart and brain organ simultaneously for recovery of melituria.

Three, prescription science, raw material is natural, has no toxic side effect.

Pancreas islet Vitality Source is the pure natural preparation for collecting gene biological technical ability and plant extracts, and bioactivity is common hypoglycemic Ten times or more of product.Pancreas islet Vitality Source is without any side effects according to clinical verification, not the impariment of the liver, kidney, and diabetic can put The heart is taken for a long time.

Four, high-end dosage form, it is rapid-action, effect is good.

Present composition dosage form is advanced, high in technological content.Take rear easy disintegrating, rapid-action, good absorbing.It is substantially better than biography The formula of system.

Five, diabetic does not have to lifelong medication.

The extraction of active ingredient height, the hyperconcetration of the present composition, breach stimulation and discomfort of the previous capsule to stomach Reaction, and broken the shortcomings of Chinese traditional herbs dosage is big, absorption is few, it is ensured that human body fully absorbing and utilizing to drug. The treatment phase of drug has been greatly shortened, has achieved the purpose that short-term rehabilitation is discontinued.

The invention has the advantages that

1. 24 kinds of Chinese herbal medicine extracts of the composition selection of the present invention, Chinese herbal medicine material its extract for having drawn from common, no It sticks to tradition and produces Chang Fang, the different pathogeny interpretation of the cause, onset and process of an illness of hyperglycemia is directed to using pure natural Chinese herbal medicine extract, has broken clinic In conventional treatments, it is rapid-action, absorb thorough, significant effect, reduce side effect, conditioning viscera, Yin Yang balancing is comprehensive to adjust Manage diabetes.

2. the composition of the present invention is mutually acted synergistically using the active constituent of 24 kinds of Chinese herbal medicine extracts, mutually increase work( Effect matches mineral trace element chromium needed by human, selenium, zinc, magnesium, formula uniqueness, obvious effect, the hair according to diabetes patient Anttdisease Mechanism carries out specific aim adjusting, systematicness conditioning, and help combines, and has apparent blood sugar reducing function.

3. the composition compatibility of the present invention is made a general survey of, full side, proportioning is proper, hangs together, and both improves human metabolism function, The resistance of insulin is enhanced, and promotes the digestion, absorption, transportation capabilities of liver and spleen and stomach and intestine, reaches the work for reducing blood glucose With.

4. prepared by the present invention has the composition for reducing blood glucose effect, to hyperglycemia the effect of notable, total effective rate reaches It is the specific short of the wholistic therapy diabetes of a new generation to 96% or more.

1. banaba leaf extract：Lagerstroemia speciosa (Linn.) Pers. Extract is called it is observed that various plants extract is thin to ehrlich ascites cancer It is found after the effect of born of the same parents' intake mouth glucose, banaba is one of the plant for promoting intake.Therefrom be separated to laughable Soviet Union's acid and Two kinds of triterpene compounds of maslinic acid, the former is the promotion object of glucose transport, therefore has hypoglycemic activity.Banaba Extract promotes absorption and utilization of the cell to glucose, to realize its effect of lowering blood sugar by the transhipment of excited glucose. Lagerstroemia speciosa (Linn.) Pers. Extract is similar to insulin to the excitation of glucose transport, and therefore, Lagerstroemia speciosa (Linn.) Pers. Extract is also referred to as Glucokinin.Clinical research discovery can adjust internal insulin and blood-sugar content after taking the drug, have and significantly subtract Fertile trend, the process are relatively more slow and without diet.Lagerstroemia speciosa (Linn.) Pers. Extract total triterpene can very significantly improve diabetic Glucose tolerance, reduce the blood glucose of diabetic, glucose in urine and saccharification hemalbumin, have hypoglycemic effect to diabetic.

2. faenum graecum seed extract:Its primary efficacy has, and has mitigation climacteric syndrome, treatment constipation, dysentery, digestion are not It is good, diabetes are controlled, cholesterol is reduced, releive sore throat and cough promote mammary development and the effects that pregnancy period milk production.From Gu To 19 th century laters, faenum graecum, using a key player is above played, is one of foremost chest enlarge draft in the whole world in herbal medicine. Modern scientific research confirms that faenum graecum can also reduce cholesterol, control and treatment diabetes and climacteric syndrome.In India, It is mixed into curry powder.India traditional herbal medicines scholar is just one of the prescription for exciting breast milk it.

The main component of faenum graecum seed has the alkaloids such as erythricine, carpaine, choline, trigonelline, sapogenin master If diosgenin, Yamogenin and a small amount of gitogenin, trace Tigogenin.Still isolate Polygonum Bi elements or different Polygonum The Arabic glucoside of careless element, two glucoside of glucose rhamnose of flavones, the flavonoids such as cyanidenon.General group of seed becomes: Moisture 10.30%, ash content 3.15%, lipase 37 .61%, total protein 16.97%, total reducing sugar 3.68%, cellulose 6.4%, hemicellulose 11.98%.Solid fatty acid 92.9%, volatile fatty acid 1.5%, not saponification ingredient 0.9% in fat oil;Lecithin 6.25% is planted Object sterol 0.5 reveals.It is mainly linoleic acid and palmitic acid in aliphatic acid, and has a small amount of oleic acid and leukotrienes.Nucleoprotein in protein 55%.It is mainly galactomannan, also -320 microgram % containing vitamin B1 in total reducing sugar.Leaf about 43 milligrams of % containing ascorbic acid. Herb is also rich in calcium, iron, carrotene etc..The mucus of galactomannans class contained by faenum graecum and steroid saponin have drop in ten days Blood glucose, diuresis, anti-inflammatory isoreactivity.Clinical report, control diabetes often take daily 25g faenum graecum seeds, take 21 days, can significantly drop altogether The blood glucose and glucose in urine content of low diabetes patient.

3. guava leaf extract:Guava Leaf itself is rich in abundant nutritional ingredient, wherein protein and Vitamin C In addition the height of content especially also contains vitamin A, B and microelements of calcium, phosphorus, iron, potassium etc..Guava Leaf, which is also rich in, meals Eat the nutritional ingredients such as fiber, carrotene, fat.In addition contain the nutritional ingredients such as fructose, sucrose, amino acid in Guava Leaf.① Most of glycosurias have a significantly scarce chromium phenomenon in patient body, and micro " have containing abundant in Guava Leaf fruit and leaf Machine chromium ", chromium are the essential trace elements of the human bodys, are played an important role in normal glycometabolism and fat metabolism.2. containing fibre Dimension is high, can effectively drain and accumulate residue extra in the intestine.3. rich in vitamin C, iron, calcium, the minerals such as phosphorus have anti-old Change and anti-oxidation efficacy, energy skin whitening prevent blackspot and freckle from being formed, increases skin to the resistance of ultraviolet light, be Ms Skin of staying pale optimal selection.Body vitamin at least demand is supplemented, there is antialcoholism function to the excess person that drinks.

Efficacy effect:Guava Leaf originates in South America, the cultivation of In South China various regions.Guava Leaf both can with belt leather or It is edible with peeling, it fresh fruit can be done eats it raw and also cook, there is the effect of astringing to arrest diarrhea, anti-inflammation hemostasia, can be used for acute and chronic Enteritis, dysentery, the illnesss such as children's indigestion.1. strengthen immunity:Guava Leaf is best one of vitamin C sources, is contained Measure very rich, and vitamin C is a kind of antioxidant, can enhance siberian crabapple altogether function, and protection human body is resisted disease and invaded It attacks such as flu and influenza.2. hypoglycemic:Contain abundant trace element " Organic Chromium " in Guava Leaf fruit and leaf, chromium is human body Required trace element plays an important role in normal glycometabolism and fat metabolism.3. anticancer:Guava Leaf with it is western red Persimmon is equally rich in lycopene, this is a carotenoid compounds, has very strong inoxidizability, tumour can be inhibited thin Born of the same parents are proliferated and prevent healthy cell canceration;In addition, abundant VC contents, which also contribute to human body, removes vivo oxidation free radical, reduce Cell damage has the function of preventing colon cancer, cutaneum carcinoma, prostate cancer, gastric cancer, carcinoma of mouth, breast cancer and lung cancer.3. dropping blood Pressure:Guava Leaf contains the potassium of a large amount, the pressure for contributing to balanced human's extracellular Na+ion to generate.Potassium ion additionally aids blood The logical effect of liquid stream, reduces the risk of heart attack and apoplexy.5. Guava Leaf contains vitamin, as vitamin E, K, pantothenic acid, The minerals such as vitamin B6, niacin, folic acid and copper, manganese, magnesium promote blood to be formed.Vitamin C in Guava Leaf can also promote Body absorbs more iron, to promote hemoglobin to generate.6. anti aging effect:Because being melted into rich in antioxygen in Guava Leaf Vitamin C and lycopene can effectively reduce detrimental effect of the free radical to skin.7. anti-inflammatory:Guava Leaf and Guava Leaf Leaf extract has anti-inflammatory property.The edible this fruit of people for suffering from chronic ache is invaded to resist inflammation.8. protecting eye Eyeball:The vitamin A of improving eyesight is rich in Guava Leaf, and antioxidant content has the function of that protect eyes are lacked by free radical injury, Because antioxidant content can protect retina.Mostly edible Guava Leaf can be effectively improved eyesight, protect eyes from old age Property macula lutea and senile cataract puzzlement.

4. money willow extract:It is called blue or green money willow extract, contains many substances, money willow polysaccharide in money willow extract With good hypoglycemic effect, hyperglycemic patients sugar tolerance can be effectively improved.Blue or green money willow in money willow extract simultaneously Glycosides is a kind of natural sweetener, and is non-calorific value saponins, disclosure satisfy that demand of the hyperglycemic patients to sweet taste, without aggravating The state of an illness, while there is good effect in terms of hypoglycemic, lowering blood pressure and blood fat.Thus blue or green money willow extract/money willow carries It is good hypoglycemic product to take object.Blue or green money willow flavones in blue or green money willow extract can effectively remove internal oxygen radical, change Kind blood circulation, reduces cholesterol, and expansion of coronary artery prevents cardiovascular and cerebrovascular disease.1. hypoglycemic:Money willow contains rich Rich water extract and alcohol extracting can increase vasopermeability, and expansion artery improves blood circulation, and sugared generation is adjusted to play It thanks, reduces the purpose of blood glucose.2. reducing blood lipid:Money willow contains triterpene, flavones and polysaccharide etc., there is very strong effect for reducing blood fat, Internal metabolism is can effectively improve, to prevent the raising of total cholesterol.3. blood pressure lowering:Money willow can restore the pancreas islet of lesion The structure and function of cell, to increase internal peripheral organization pancreas islet receptor, thus reached the work to reduce blood pressure With.

5. hypoglycemic grass extract:Hypoglycemic agrostology name " Radix et Rhizoma Gynurae divaricatae " is called Radix Rhodiolae, composite family gynura segetum category perennial root Herbaceous plant.Its primary efficacy:Analgesia, hemostasis, anticoagulation, hypoglycemic, antitumor action.It has very magical health care work( Effect, contains very abundant nutriment, such as phycocolloid element, vitamin B, amino acid, it has extraordinary effect of reducing blood sugar Fruit, at the same it can also lowering blood pressure and blood fat, have very magical effect to the inhibition of diabetes.

6. garlic P.E:Garlic P.E is exactly allicin, and shape is faint yellow fine powder.With antibacterial, resist Hepatotoxicity wind agitation and anti-aging and other effects.Allicin is the important component for having extensive drug effect, have activating cell, promote energy production, The effects that increasing antibacterial and anti-virus ability, accelerating metabolism, relieve fatigue.Allicin can and other materials (carbohydrate, lipid, Protein etc.) generation compound action is combined, it also expands blood vessel, improve sanguimotor effect.Its primary efficacy:1. preventing dynamic Pulse atherosclerosis, cardioprotection is from invasion;2. having the function of clear pest, removing toxic substances, promoting blood circulation and removing blood stasis;3. antiviral effect;③ Reducing blood lipid, blood pressure lowering, hypoglycemic also anti-platelet aggregation;5. improving the activity of fibrinolytic enzyme, having inhibition to tumour cell and killing The effect of going out, anti-curing oncoma;It, can be with antithrombotic 6. it can reduce Coronary Atherosclerotic Plaque;7. health care, growth promotion are made With.In terms of garlic P.E is mainly used in sterilization, health care, growth promotion.

7. Shorthorned Epimedium P.E:Have effects that kidney-replenishing, strong muscles and bones, dispelling wind and eliminating dampness.It is mainly used for tonifying kidney and strengthening yang, controls Treat caused by wind, cold and wetness evils, strong muscles and bones, blood pressure lowering, enhancing sexual desire.It is wet to cure mainly impotence due to deficiency of the kidney, infertile, frequent micturition, muscles and bones impotence, chill The cards such as numbness, extremity numbness.

8. Radix Trichosanthis extract:For the root of cucurbitaceous plant snakegourd, it is a kind of clearing heat-fire class Chinese medicine, there is clearing heat-fire, It promotes the production of body fluid to quench thirst, fall fire is moisturized, the effect of apocenosis detumescence.Mainly act on that pyreticosis is thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle swells etc. Illness.The trichosanthin contained in root of Chinese trichosanthes being capable of effective antitumor, antiviral, raising body immunity.Contain in root of Chinese trichosanthes Root of Chinese trichosanthes agglutinin be a kind of phytolectin of gala sugar specificity, have proof, root of Chinese trichosanthes agglutinin in vitro experiment With Anti-lipolytic and promote the insulin-like effects such as Fatty synthesis, there is specific bond power, help to reduce glycosuria galactolipin The incidence of disease.The glucose contained in root of Chinese trichosanthes, galactolipin, fructose, the polysaccharide materials such as mannose can help anticancer, improve Immunocompetence.And radices trichosanthis polysaccharide also has hypoglycemic effect.

9. Corn silk P.E:.From the style and column cap of grass maize.Modern pharmacological studies have shown that 1. diuresis:There is diuresis to people or rabbit, chloride discharge rate can be increased, the insoluble part of aqueous extract methanol is passed through Dialysis person's diuresis is most strong.Diuresis is mainly the outer property of kidney, very weak to the effect of kidney.2. reducing the effect of blood glucose: The leavening of corn stigma has the reduction blood glucose of highly significant to act on rabbit.3. cholagogic, anastalsis:Corn stigma can promote Into bile excretion, its viscosity is reduced, reduces its BILE PIGMENTS content, thus it is medicinal to can be used as cholagogic.

10. burdock extract:Can be by inhibiting a- glucosidase activities to play hypoglycemic effect, it can significantly for a long time Reduction blood glucose, and improve to the dosis tolerata of carbohydrate.Great burdock achene is resistant to nephropathy, inhibits the work of the excretion of Urine proteins With there is certain therapeutic effect to hyperglycemia nephrosis;In addition its energy antibacterial, antiviral, raising immunity, are easy diseases caused by external factors, burdock Son is very useful to this.

11. Astragalus Root P.E:Pharmacological research shows that Radix Astragali has dual regulation to blood glucose, has and reinforces myocardial contraction Power, diastole coronary vasodilator, reduces blood pressure, and protects liver cell, reduces the effect of blood glucose.Astragaloside can be by promoting pancreas islet β thin Intracrine insulin plays hypoglycemic effect, and astragalus polyose has protective effect to the cardiac muscle of diabetes.Active constituent in Radix Astragali Astragalus polyose can mitigate endoplasmic reticulum damage by improving the er stress of liver, increase glycogen synthase activity, increase pancreas Island element signal protein synthetic quantity and activity, to play antidiabetic effect.Chinese herbal medicine astragalus can enhance and adjust immune response effect It answers, there is urine detumescence, prevent or reverse Urine proteins effect, fibrosis, the hardening process of renal tissue can be delayed, to diabetogenous nephrosis Disease progression has certain prevention effect.Astragalus in Treating diabetes recent studies have shown that astragalus polyose is that have to live compared with Johnson ＆ Johnson's object Property macromolecular compound, it is no matter oral or astragalus polyose is injected intraperitoneally, can significantly reduce KKAy Mouse Weight, blood glucose and insulin resistance index, moreover it is possible to improve impaired glucose tolerance, slim the abdomen, increase insulin sensitivity, But do not influence insulin secretion.

12. Cortex Lycii extract:Also known as boxthorn root, it is one kind of Chinese medicine, dark tan powder.With cool blood except steaming, clearing lung-heat The effect of fall fire.Root bark of Chinese wolf-berry decoction gives rabbit gavage, first makes the raising of blood glucose short time, then persistently reduces, and reduces within 4-5 hours It is most apparent, 14% is averagely reduced, is maintained 4-8 hours, it is oral to tissue of experimental diabetic mice pancreas then to restore normal root bark of Chinese wolf-berry decoction The morphosis damage of island B cell also has certain mitigation to act on.The root bark of Chinese wolf-berry is to mouse glucose and adrenal gland disposition hyperglycemia There is significant hypoglycemic effect..Pharmaceutical research shows that the root bark of Chinese wolf-berry has the function of apparent blood pressure lowering and hypoglycemic.

13. mulberry bark extract, mulberry-leaf extract:Hypoglycemic effect research to the drug of 50 kinds of traditional treatment diabetes Show there is significantly reducing blood glucose, especially it is the most apparent to reduce blood glucose effect for the root bark of white mulberry.Pharmacological research proves, Mulberry leaf have the function of that inhibition blood glucose rises, and can prevent and treat diabetes to a certain extent.With reduction blood glucose, reduce blood Pressure reduces the various health care functions such as blood fat, anti-aging.

14. Fructus lycii P.E:With immunological regulation, hypoglycemic, reducing blood lipid and other effects.Modern analysis shows the fruit of Chinese wolfberry Contained nutritional ingredient is very abundant, also contain the multiple elements such as abundant potassium, sodium, calcium, magnesium, zinc and 24 kinds of amino acid and Multivitamin.Active ingredient is polysaccharides.There is kidney-supplementing liver-boosting, controls the deficiency of liver-yin and kidney-yin, quench one's thirst and other effects.With reduction blood Sugar reduces blood pressure and lipotropic effect.The decline that Fructus lycii P.E can promote diabetes glucose lasting, to diabetic Blood glucose, blood fat increase, and dysphotia has improvement result.Modern pharmacological studies have shown that the fruit of Chinese wolfberry is not only full of nutrition but also certain With various health functions.It is carried out with isolated sterling (pure fraction) polysaccharides (LBP-1,2,3,4) Function assessment evaluation experimental further demonstrates that:Polysaccharides is strictly the important function factor that the fruit of Chinese wolfberry has many pharmacological actions One of.

15. kudzu root extract:It is the main component of isoflavones in legume pueraria lobata root dry root.Through its multipath, more The mild action of target spot is sticked and is assembled in clinical antiplatelet, and Hemorheology state is improved, and expansion artery blood vessel adjusts blood Fat, it is hypoglycemic etc. to embody curative effect that is unique and determining.Pueraria lobata can reduce the blood of alloxan and streptozotocin rat Sugar and glycosylated hemoglobin, improve serum insulin level, and Puerarin can also enhance sensibility of the histocyte to insulin.Pueraria lobota Root can block contraction of the receptor,β to blood vessel, expand blood vessel, mitigate the effect of confrontation insulinotropic hormones, improve Insulin sensitivity.Microcirculation can also be improved, reduce whole blood viscosity, improve cell calcium-magnesium-ATPase activity, promoted Sugar entering and insulin transdermal delivery.Flavones in kudzu root extract can increase brain and coronal vascular flow, and vascular resistence reduces, tool It has antihypertensive effect, Puerarin can be such that blood glucose is decreased obviously, and hypoglycemic effect is lasting.

16. Bitter Melon P.E:Pharmacological research shows that balsam pear crude extract tool is significantly reduced blood glucose effect.Radiation is exempted from Epidemic disease method, which measures Bitter Melon P.E and insulin receptor, insulin antibody, apparent association reaction, shows that it is known as with pancreas islet Common antigenicity and bioactivity.Therefore balsam pear crude extract has the function of similar insulin.On the one hand balsam pear inhibits sugar different Raw key enzyme generates blood sugar reducing function, on the other hand reinforces grape by activating the glucose-6-phosphate dehydrogenase (G6PD) of alternative pathway The oxidation of sugar utilizes.Balsam pear can not only promote glucose tolerance in mice and insulin tolerance, but also can also adjust insulin receptor phosphorus Acidification level and its downstream signaling molecule, so as to improve body insulin resistance.

17. cinnamomum cassia extract:Modern pharmacological studies have shown that Chinese cassia tree can reduce the blood glucose of diabetic.Take high dose The average blood glucose levels of Chinese cassia tree drop to 8.0 from 8.9, and the average blood glucose levels for taking low dosage Chinese cassia tree drop to 8.2 from 8.9, The blood glucose for not taking in Chinese cassia tree does not change.Chinese cassia tree reduces the pharmacological mechanism of blood glucose effect mainly by protection, stimulation pancreas islet β Cell and the content for increasing serum insulin;Increase the sensibility of insulin, improves insulin resistance ability, contribute to internal Portugal The metabolism of grape sugar;Remove free radical, anti peroxidation of lipid;Promote insulin secretion, increases the content of serum insulin.

18. Salvia root P.E:There are promoting blood circulation, promoting circulation of blood, cool blood, blood-nourishing, it can stagnation resolvation, dredging collateral.Radix Salviae Miltiorrhizae decoction can be apparent Reduction blood glucose, as long as retaining potency for 5 hours, and blood fat and blood viscosity can be reduced.

19. Rhizoma Polygonati extract:With 1. bacteriostatic and disease prevention.Sealwort can play the effect of certain antibacterial and antibacterial action, And some illnesss caused by dermatophyte can also be alleviated.In addition to this, additionally it is possible to reinforce myocardial function, prevent The illness of cardiovascular aspect occurs.2. hypoglycemic.Modern medical studies have confirmed that sealwort contains clayey liquid, starch, carbohydrate, Tianmen Winter propylhomoserin, cardiac glycoside etc. can reduce blood pressure, coronary blood flow made to increased, and can inhibit glucose in urine and blood glucose, especially pair Blood glucose caused by adrenaline is excessively high apparent inhibiting effect.3. nourishing Yin and moistening lung.Sealwort has the effect of good nourishing Yin and moistening lung Fruit, while can also achieve the effect that promote the production of body fluid to quench thirst, kidney-tonifying health-care, can also it play the role of for benefiting the spleen for nourishing blood good.4, sealwort Also have the effect of blood pressure lowering, hypoglycemic, reducing blood lipid, be equally also prevented from atherosclerosis, reach anti-aging and resists The effect of bacterium, sealwort also have the function of immune activation.

20. Semen Coicis extract:In fine brownish-yellow powder, be tonifying lung invigorating the spleen, promoting urination and removing dampness food and medicament dual-purpose product, be Splendid beauty food materials, especially contained proteolytic enzyme can be such that skin keratin softens, and vitamin E has antioxygen to be turned into With.Modern pharmacological research shows that coix seed has the function of reducing blood glucose, is particularly suitable for obese diabetic with hypertension Person.

21. Rhizoma Polygonati Odorati extract:With nourishing yin to moisten dryness, QI invigorating nourishing the stomach, heat-clearing, promote the production of body fluid to quench thirst and other effects.As tonic, Cure mainly the diseases such as consumption of YIN caused by febrile disease, abnormal heat cough caused by dryness, heart disease, diabetes.It is mainly used for promoting the production of body fluid to quench thirst, drops internal heat, reducing blood lipid, cardiac stimulant shield The heart, anti-aging.

22. cornel extractive:The alcohol extracting thing of Fructus Corni is not only to alloxan and epinephrine glycosuria disease rat There is the apparent blood glucose that reduces to act on, and be formed by diabetes rat to streptozotocin (STZ) also to have similar effect, but right Normal rat blood glucose has no significant effect.Experiment shows:Fructus Corni pulvis, ether extract and the equal energy of ursolic acid further detached Blood glucose, glucose in urine, amount of drinking water and urine volume are significantly reduced, illustrates that ursolic acid is the active constituent of Fructus Corni anti-diabetic, there is report Announcement is pointed out, is tested with rat epididymis adipose tissue and is found that Fructus Corni has insulin-like effects, Fructus Corni tannic acid that can inhibit lipid mistake Oxidation prevents lipolysis, and adrenaline and adrenocorticotropic hormone can also be inhibited to promote the effect of lipolysis.Fructus Corni With tonifying the liver and kidney, puckery essence prevent prolapse.For dizziness and tinnitus, soreness of waist and knee joint, impotence and seminal emission, profuse sweating collapse, Heat Diabetes.

23. anemarrhena asphodefoides extract:The rhizome of Liliaceae herbaceos perennial rhizoma anemarrhenae is mainly extracted, appearance is brown color essence Fine powder.The active ingredient of anemarrhena asphodefoides extract includes containing a variety of steroid saponins, mucilaginous substance, niacin.Its primary efficacy:Heat-clearing is rushed down Fire, enriching yin cough caused by dryness, quench one's thirst, hectic fever due to yin labor heat, the diseases such as insomnia.Rhizoma anemarrhenae water logging extract, can reduce the blood glucose level of normal rabbit, especially It is more notable to the effect of alloxan diabetes rabbit.The application field of anemarrhena asphodefoides extract:1. anemarrhena asphodefoides extract is as sterilization The application of agent.2. application and anemarrhena asphodefoides extract of the anemarrhena asphodefoides extract in preparing improvement insulin resistance drug are preparing prevention Application in tachyarrhythmia and essential hypertension drug.

24. ginseng:It is for example weak, thirsty, empty that pharmacological research shows that ginseng treatment diabetes can not only improve general symptom It is weak etc., and blood glucose and glucose in urine can be reduced.Suitable for it is light-duty, diabetes mellitus type.Differential diagnosis in tcm kidney deficiency, gas deficiency of Yin person curative effect are more Good, the scorching person of the deficiency of Yin should not take.

25. spirulina extract:Spirulina, also known as " arthrospira ", are grown in various fresh water and seawater.Spirulina is rich in The substances such as chlorophyll, phycocyanobilin, creatine have the toxic side effect reaction for mitigating cancer radiation, chemotherapy, improve immune function, drop Low blood fat and other effects.1. adjusting blood glucose:It, can be by a variety of there are a variety of sugar reducing substances such as spirulina polysaccharide, magnesium, chromium in spirulina Approach (such as promote insulin secretion, slow down sugar absorption, promote metabolism, is anti-oxidant) adjusts metabolism of blood glucose.2. reducing courage Sterol:Cholesterol reduces the breaking-out that can effectively prevent heart disease and stroke disease, and the Y- leukotrienes in spirulina can drop Cholesterol contained by low human body lowers cholesterol so as to effectively reduce blood pressure and prevent heart disease.3. treating anemia:Spiral shell It revolves and contains abundant active iron, vitamin B12 and chlorophyll in algae, they are the raw material and coenzyme of synthesis hemoglobin, and Phycocyanin, polysaccharides in spirulina can enhance polychromatic erythrocyte and the ratio for just incarnadining cell in mouse bone marrow cells, therefore Spirulina can promote hemoglobin synthesis and hemopoietic function of bone marrow from many aspects, play the effect of anti-anemia action.3. antifatigue:Freely Base is one of the root of human senility and disease, and superoxide dismutase (S0D) can be reacted with catalytic disproportionation removes free radical.Spiral shell Rotation algae can mitigate oxygen free radical injury caused by movement, protect membrane structure, have anti-sports fatigue to act on.5. protecting intestines Stomach:Most of patients with gastric disease belongs to hyperhydrochloria, leads to the diseases such as gastritis, gastric ulcer, and spirulina is basic food, is inside contained Very high vegetable protein and abundant chlorophyll, beta carotene etc., these nutrients neutralize hydrochloric acid in gastric juice and gastrointestinal tract is viscous Film reparation, regeneration and normal secretions function are extremely effective, especially suitable for stomach patient.6. enhancing immune system:Due to spiral Polysaccharides and phycocyanin in algae can enhance the proliferation activity of bone marrow cell, promote the life of the immune organs such as thymus gland, spleen Biosynthesis that is long and promoting haemocyanin, therefore spirulina has immunological enhancement.7. anti-cancer tumor suppressor:Anti- mutation and anticancer The mechanism of action of drug is related with the reparation of DNA (DNA), polysaccharides, beta carotene, phycocyanin in spirulina There is this effect, therefore spirulina shows important function in terms of antitumor, anti-cancer.

26. Ramulus euonymi:For the branch or aliform adjunct of the tool fin of Celastraceae plant winged euonymus, have blood-breaking promoting menstruation, The effect of removing toxicity for detumescence, desinsection, hypoglycemic, cardiac stimulant.Blood sugar reducing function Oxaloacetic sodium ingredient contained by Ramulus euonymi, can promote pancreas Insulin secretion is reinforced in beta cell hyperplasia, a- cellular atrophies, thus plays the role of reducing blood glucose.It is raised in Ramulus euonymi decoction Oxaloacetic sodium ingredient has blood sugar reducing function.Clinic Ramulus euonymi 30g, is equal with chinaroot greenbrier, raw pueraria lobata and uses, to mild diabetes, Or blood glucose maintains light, moderate increasing state after taking antidiabetic drug, adds with after these Chinese medicines, Chinese and Western medicine is used in combination, and can heighten the effect of a treatment, blood Sugar can decline at leisure, until normal range (NR).Winged euonymus cardiac glycoside contained by Ramulus euonymi has cardiac stimulant and coronary dilatation effect, Ji Nengzhi It connects and acts on cardiac muscle cell, play cardiac effect, and make coronary artery dilator and peripheral vessels play effect promoting blood circulation and removing blood stasis, it is right The heart diseases myocardial damages such as coronary heart disease, high heart, myocarditis have auxiliary therapeutic action.

27. the coptis:According to clinical report, coptis treatment diabetes can be such that blood glucose significantly reduces.Experiment shows berberine Hypoglycemic mechanism has no effect on the secretion and release of insulin, nor affects on the number and affinity of Hepatocyte Insulin, and It is to generate blood sugar reducing function by inhibiting gluconeogenesis and promoting glycolysis.

28. radix rehmanniae recen:There is nourishing Yin and clearing heat.Blood glucose can be made significantly to decline, also can inhibit and prevent adrenaline Caused blood glucose rises, and can improve the hyperlipidemia of diabetic keratopathy, the hyperglycemia state of an illness.Clinical application is when diabetes, mostly with life Glutinous rehmannia is with asparagus fern, fruit of Chinese wolfberry etc..

29. Schisandra chinensis:Its fruit contains schizandrin and vitamin C, resin, tannin and a small amount of carbohydrate, can enhance and be immunized, prolongs Seminal emission is controlled in slow aging;It also can gentle palmic rate and alleviation hypertension.1. Schisandra chinensis is that effect is distinguished, unisex yin-nourishing One of controlling nocturnal emission with astringent drugs tonic.2. liver protecting:Schisandra chinensis can promote the detoxification processes of liver, protect liver from poisoning, and can regenerate The impaired liver organization because of abuse of alcohol, drug or hepatitis.3. shield heart cardiac stimulant:It can generate protective effect to heart tissue, It also can gentle palmic rate and alleviation hypertension.3. anti-anti- free radical infringement:Free radical be cause atherosclerosis, cancer, Coronary heart disease and immune hypodynamic main cause, and cause the arch-criminal of ageing process acceleration.Wood contained by Schisandra chinensis Phenol element is potent antioxidants, can inhibit free radical, and can increase the level of antioxidant-glutathione of liver.5. enhancing Physical efficiency:Schisandra chinensis can enhance endurance and strength and accelerate antisecosis.6. enhancing anti-pressure ability:Schisandra chinensis is most effective plant One of agent is adapted to, intelligence, physical efficiency and sense organ function can be promoted, and enhance the resistance to pressure.In brief, it can help people Body bears the pressure factor of such as hot and cold, noise, mood excess load etc, thus contribute to promoted work performance, enhancing endurance and It lessens fatigue.Also have the function of that promoting intelligence perfects, slows down aging simultaneously.

30. Cr-enriched yeast:Chromium is one of safest the essential trace elements of the human body, many to be acted on diabetes about inscription Research shows that:Trace element chromium is in close relations with diabetes.Chromium mainly reinforces insulin function to the effect of glycometabolism. In the tissue for relying on insulin, even if the only increase of milli trace chromium, insulin function will be improved significantly;Chromium is taken in not Foot, body can increase the demand of insulin.Normal person's demand is 20-50 μ g/ days, and children, pregnant woman and old man are 50- 110 μ g/ days, diabetic and obese people are 50-200 μ g/ days.Chromium is nearly all trivalent in human body, in wholefood Content it is relatively low, in the form of trivalent exist.Trivalent chromium is the central active ingredient of glucose tolerance factor.Scarce chromium is to cause sugar The pathogeny sexual factor of urine disease, atherosclerosis.Scarce chromium can be with impaired glucose tolerance, the reduction of pancreas islet affinity, beta cell sensibility It reduces, insulin receptor reduction, blood glucose is too high or too low.Above-mentioned exception can be corrected after mending chromium.Cr-enriched yeast can reduce The blood glucose of diabetic can also improve its hypoglycemic reaction, have the dual regulation effect to blood glucose, can effectively control sugar Urine disease, eliminates the abnormal phenomenon in terms of glucose tolerance.Scientists point out how to go that diabetic is instructed rationally to absorb this Kind trace element, and be not to generate another side effect, then become a recent studies on project.And most safe, most effective side Method is most safe using glucose tolerance factor chromium, and yeast chromium is safest at present.

31. Se-enriched yeast:It is that selenium element is added during culture yeasts, selenium has been absorbed and utilized in when yeast growth, makes Selenium in yeast protein and polysaccharide organic combined and be converted into Biological Selenium, it is secondary anti-to the poison of human body to eliminate chemical selenium It should be stimulated with stomach, enable that selenium is more efficient, be more safely absorbed by the body utilization.Se-enriched yeast be also so far it is domestic most Efficiently, the most balanced selenium-replenishing preparation of most safe, nutrition.Selenium is micro- necessary to human body, and selenium can prevent and inhibit swollen Tumor, anti-aging, the normal function for maintaining cardiovascular system, the appearance of prevention of arterial hardening and coronary heart disease.Selenium-supply can reduce liver cancer, The incidence of gastric cancer, lung cancer, prostate cancer and the carcinoma of the rectum.Selenium is referred to as " treating liver necrosis protective factors ", is to prevent hepatonecrosis One of factor.Selenium can stimulate the generation of immunoglobulin, and the various immune functions of human body is made to be improved.Diabetes patient's blood selenium is bright The aobvious blood selenium less than normal person.Selenium-supply can reduce blood glucose level, while increase the activity of GPX.Selenium has insulin-like effects, Target tissue can be promoted not increase insulin level in blood while reducing blood glucose using glucose, cell in terms of fat can be stimulated The transport process of glucose transporter on film, this provides opportunity for the treatment of diabetes hyperinsulinemia patient.

32. Zinc-rich saccharomyces cerevisiae:Zinc is one of the essential trace elements of the human body, and the constituent as a variety of enzymes widely participates in Various metabolic activities.In human body, zinc is the widest essential trace element of distribution, and intracellular most abundant micro member Element.In vital movement, zinc plays " life gear " effect and DNA replication dna, the rna transcription of transhipment matter and energy metabolism The required structural constituent of required enzyme is synthesized with nucleic acid.

Specific implementation mode

To make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, with reference to Specific implementation mode, the present invention is further explained.

Embodiment 1

A kind of Chinese medicine composition for reducing blood pressure includes the substance of following parts by weight:

60 parts of banaba leaf extract, 100 parts of faenum graecum seed extract, 100 parts of money willow extract, hypoglycemic grass extract 60 Part, 100 parts of guava leaf extract, 60 parts of garlic P.E, 130 parts of burdock extract, 40 parts of Corn silk P.E, excessive sheep 30 parts of leaves of pulse plants extract, 60 parts of Astragalus Root P.E, 30 parts of Cortex Lycii extract, 60 parts of mulberry bark extract, mulberry-leaf extract 120 Part, 30 parts of Fructus lycii P.E, 60 parts of kudzu root extract, 60 parts of Bitter Melon P.E, 120 parts of cinnamomum cassia extract, Salvia root P.E 20 parts, 60 parts of Rhizoma Polygonati extract, 20 parts of Semen Coicis extract, 100 parts of Radix Trichosanthis extract, 30 parts of Rhizoma Polygonati Odorati extract, Fructus Corni 120 parts of extract, 60 parts of anemarrhena asphodefoides extract, 30 parts of ginseng, 100 parts of spirulina, 60 parts of Ramulus euonymi, 45 parts of the coptis, radix rehmanniae recen 40 Part, 30 parts of Schisandra chinensis, 2 parts of Cr-enriched yeast, 2 parts of Se-enriched yeast, 1 part of Zinc-rich saccharomyces cerevisiae, 6 parts of magnesium stearate.

Embodiment 2

A kind of Chinese medicine composition for reducing blood pressure includes the material composition of following parts by weight:

100 parts of banaba leaf extract, 60 parts of faenum graecum seed extract, 100 parts of money willow extract, hypoglycemic grass extract 60 Part, 100 parts of guava leaf extract, 30 parts of garlic P.E, 130 parts of burdock extract, 90 parts of Corn silk P.E, excessive sheep 90 parts of leaves of pulse plants extract, 120 parts of Astragalus Root P.E, 60 parts of Cortex Lycii extract, 30 parts of mulberry bark extract, mulberry-leaf extract 6120 Part, 30 parts of Fructus lycii P.E, 60 parts of kudzu root extract, 120 parts of Bitter Melon P.E, 120 parts of cinnamomum cassia extract, Salvia root P.E 20 parts, 60 parts of Rhizoma Polygonati extract, 40 parts of Semen Coicis extract, 100 parts of Radix Trichosanthis extract, 60 parts of Rhizoma Polygonati Odorati extract, Fructus Corni 120 parts of extract, 60 parts of anemarrhena asphodefoides extract, 80 parts of ginseng, 100 parts of spirulina, 100 parts of Ramulus euonymi, 15 parts of the coptis, radix rehmanniae recen 20 Part, 60 parts of Schisandra chinensis, 6 parts of Cr-enriched yeast, 4 parts of Se-enriched yeast, 1 part of Zinc-rich saccharomyces cerevisiae, 2 parts of magnesium stearate.

Embodiment 3

A kind of Chinese medicine composition for reducing blood pressure includes the material composition of following parts by weight:

80 parts of banaba leaf extract, 90 parts of faenum graecum seed extract, 60 parts of money willow extract, 100 parts of hypoglycemic grass extract, 70 parts of guava leaf extract, 50 parts of garlic P.E, 100 parts of burdock extract, 60 parts of Corn silk P.E, Herba Epimedii carry Take 70 parts of object, 80 parts of Astragalus Root P.E, 40 parts of Cortex Lycii extract, 50 parts of mulberry bark extract, 80 parts of mulberry-leaf extract, matrimony vine 50 parts of seed extract, 60 parts of kudzu root extract, 110 parts of Bitter Melon P.E, 110 parts of cinnamomum cassia extract, 30 parts of Salvia root P.E, Huang 60 parts of essence extract, 40 parts of Semen Coicis extract, 80 parts of Radix Trichosanthis extract, 60 parts of Rhizoma Polygonati Odorati extract, cornel extractive 120 Part, 30 parts of anemarrhena asphodefoides extract, 50 parts of ginseng, 80 parts of spirulina, 80 parts of Ramulus euonymi, 35 parts of the coptis, 30 parts of radix rehmanniae recen, Schisandra chinensis 50 Part, 5 parts of Cr-enriched yeast, 3 parts of Se-enriched yeast, 2 parts of Zinc-rich saccharomyces cerevisiae, 4 parts of magnesium stearate.

The preparation method of above example is：

Step 1: by 30-80 parts of ginseng, 60-100 parts of spirulina, 60-100 parts of Ramulus euonymi, 15-45 parts of the coptis, radix rehmanniae recen 20- 40 parts, 30-60 parts of Schisandra chinensis, cleaning selected with single product, air-dry purification, are respectively crushed into coarse powder, the granularity of coarse powder is 24-50 Mesh is uniformly mixed, it is spare that coarse powder mixture is made;It is divided into three parts;

Step 2: first part of coarse powder mixture is put into sealing porcelain, temperature is under 25-30 degree, spontaneous fermentation 5-7 days, fermentation After the completion, it is cleaned and is dried with clear water, obtain dry fermentation coarse powder mixture；Second part of coarse powder mixture is eluted with pure water, The cellulase of the 2-5% of second part of coarse powder total weight of the mixture is added, carries out vibration of ultrasonic wave 20-30 minutes, is sufficiently stirred, Then fermentation being sealed to coarse powder mixture, temperature is fermented 1-3 days under 25-30 degree, after fermentation, 6-8 times clear of progress It washes, squeeze, dry, obtain wet fermentation coarse powder mixture；Third part coarse powder mixture carries out naturally dry；First part, second Part and third part mixture are mixed, and mixing coarse powder mixture is obtained；Mixing coarse powder mixture is ground, ultra micro is obtained Powder mixture, the granularity of ultra micro powder mixture is at 0.1 μm -10 μm;

It is impregnated 60 minutes Step 3: small molecule energy water is added in the ultra micro powder mixture that step 2 is obtained, is made to impregnate and mix Material is closed, wherein the weight for the small molecule energy water being added and ginseng, spirulina, Ramulus euonymi, the coptis, radix rehmanniae recen, Schisandra chinensis coarse powder The ratio between total weight of mixture is 6:1;

Step 4: the mixture that step 3 obtains is placed in Multifunctional Chinese medicine extraction kettle, open multi-functional extraction kettle power supply into Row is heated to 100 DEG C, keep at this temperature constant temperature lift 1 hour, produce the first extraction mixture, then filter, obtain the No. one time extracting solution is spare;

Step 5: small molecule energy water, the weight of the weight and coarse powder mixture of the small molecule energy water of addition are added into filter residue The ratio between amount is 2:1, heating extraction, heating temperature is 100 DEG C, and extraction time is 1 hour, and second of extracting solution is obtained by filtration;

Step 6: the merging of extracting solution twice is placed in triple effect vacuum high energy evaporation concentrator, be decompressed to relative pressure be- 0.07MPa is heated to 80 DEG C, and extracting solution is condensed into the medicinal extract that proportion is 1.30, is then dried, obtains at 45-50 DEG C To dry extract;

Step 7: after dry extract is broken into 100-150 targeted fine powders, 60-100 parts of banaba leaf extract, faenum graecum is added 60-100 parts of seed extract, 60-100 parts of money willow extract, 60-100 parts of hypoglycemic grass extract, guava leaf extract 60- 100 parts, 30-60 parts of garlic P.E, 60-130 parts of burdock extract, 40-90 parts of Corn silk P.E, Shorthorned Epimedium P.E 30-90 parts, 60-120 parts of Astragalus Root P.E, 30-60 parts of Cortex Lycii extract, 30-60 parts of mulberry bark extract, mulberry-leaf extract 60-120 parts, 30-60 parts of Fructus lycii P.E, 30-60 parts of kudzu root extract, 60-120 parts of Bitter Melon P.E, cinnamomum cassia extract 60-120 parts, 20-30 parts of Salvia root P.E, 30-60 parts of Rhizoma Polygonati extract, 20-40 parts of Semen Coicis extract, Radix Trichosanthis extract 60-100 parts, 30-60 parts of Rhizoma Polygonati Odorati extract, 60-120 parts of cornel extractive, 30-60 parts of anemarrhena asphodefoides extract；It adds chromium-rich 2-6 parts of yeast, 2-4 parts of Se-enriched yeast, 1-3 parts of Zinc-rich saccharomyces cerevisiae, 2-6 parts of magnesium stearate are packed into gelatin hard after mixing Capsule to get:The present invention of every 0.45 gram of weight.

The related experimental data of hypoglycemic effect of the present invention is as follows:

1. material

1.1 sample:It is provided by central hospital of Xinxiang City, is divided into No. 1, No. 2 capsules, wherein No. 1 capsule is placebo, No. 2 capsules For the present composition.Human oral's recommended dose is 2 times a day, 2 tablets each time.Capule size:0.5g/.

1.2 love examination person's selections

1.2.1 inclusion criteria

Subject's male or female, age 18-65 Sui.Blood sampling 2 times in half a year, 2 serum total cholesterols >=5.2mmo1/L or blood Clear triglycerides >=1.65mmo1/L, simple dyslipidemia, without apparent brain, the heart, liver, lung, kidney, Hematological Diseases, no Long-term taking medicine History, voluntarily tested guarantee cooperation.

1.2.2 subject excludes mark Huaihe River

Gestation or women breast-feeding their children, to drug allergy person;Merge intentionally, liver, the serious diseases patient such as kidney and hemopoietic system;In short term Article related with tested function is inside taken, is influenced to result judgement person;Inclusion criteria is not met, it is practical not tested by regulation Sample, can not judging effect or data, umbra does not ring effect or safe sex determination person.

2. experiment

2.1 designs and grouping

Using itself between group two kinds of control designs.It is randomly divided into capsule for treating group and comfort of the present invention by subject's blood lipid level Agent control group considers the principal element such as age, gender, diet etc. for influencing result, carries out harmonious inspection, as far as possible to ensure Comparativity between group.Therapeutic test is carried out by double-blind study.

2.2 experimental method

Subject takes sample by recommended dose daily, continuously takes 45 days.Original eating habit is not changed during experiment, just Normal diet.

3. observation index

Every observation index in therapeutic test start and at the end of respectively measure it is primary.

3.1 safety indexes

3.1.1 general physical examination:The feelings such as detailed spirit, sleep, diet, stool and urine inquired and understand subject before experiment Condition measures weight, blood pressure, changes in heart rate before and after experimenter.

3.1.2 blood routine:Red blood cell count(RBC), white blood cell count(WBC) and classification, content of hemoglobin measurement etc..

3.1.3 routine urinalysis:PH value, leucocyte, glucose in urine etc..

3.1.4 stool routine examination.

3.1.5 abdominal B-scan ultrasonography, electrocardiogram, Ⅹ line fluoroscopy of chest inspection (being measured before on-test primary).

3.1.6 blood biochemistry index inspection:Total serum protein (TP), albumin (ALB), glutamic-pyruvic transaminase (ALT), millet straw turn The measurement such as ammonia enzyme (AST), uric acid (UA), urea nitrogen (BUN), creatinine (Cr), blood glucose (GLU).

3.1.7 adverse reaction is observed.

3.2 efficacy measures

Serum total cholesterol (CH0L), triglycerides (TG), high-density lipoprotein sterol (HDL-C).

4. result judgement

4.1CH0L reducing>10%;TG is reduced>15%;HDL-C rises>0.104mmo1/L;Each functional observation index Test is front and back certainly Comparison among groups have statistical significance after body compares and treats, and can judge the index positive.

Two 4.2 serum total cholesterols, triglycerides index positives, high-density lipoprotein cholesterol, which is not significantly lower than, to be compareed Group can determine that tested material has auxiliary reducing blood lipid work(effect;A positive in two serum total cholesterol, triglycerides indexs, High-density lipoprotein cholesterol is not significantly lower than control group, can determine that there is tested material auxiliary to reduce serum total cholesterol or auxiliary Reduce triglycerides effect.

5. statistical procedures

As a result mean ± standard deviation is used to indicate, self pair data uses paired t-test, in variance between test group and control group Under the premise of neat, mean compares using independent samples t-test, otherwise carries out variables transformations, meets variance and uses t to examine afterwards together, if Variance is still uneven, using rank sum test.

6. result

6.1 safety observations

6.1.1 ordinary circumstance:Treatment group 53, control group 53.Before and after treatment, curer's spirit, sleep, diet, stool and urine Situation no abnormality seen;Control group:Male/female is 20/33, and the age is 46.74 ± 11.56 years old;Treatment group:Male/female is 20/33, year Age is 46.72 ± 11.55.

6.1.2 abdominal B-scan ultrasonography, electrocardiogram, x-ray fluoroscopy of chest detection:In normal range (NR).

6.1.3 weight, blood pressure, heart rate, routine urinalysis, stool routine examination, routine blood indexes situation of change.

1 pretherapy and post-treatment weight of table, blood pressure, heart rate, routine urinalysis, stool routine examination and blood routine situation of change (Ⅹ ± S)

By table 1 as it can be seen that the forward and backward treatment group for the treatment of tested material and control group weight, blood pressure, heart rate, routine urinalysis, stool routine examination and blood Conventional rule are showed no obvious abnormalities variation, illustrate the harmful effect of the invention without above-mentioned aspect.

6.1.4 blood biochemistry index situation of change before and after therapeutic test

Changes of biochemical indexes situation (X ± S) before and after 2 therapeutic test of table

As can be seen from Table 2, the forward and backward treatment group for the treatment of tested material and control group total serum protein (TP), albumin (ALB), Gu Bingzhuan Ammonia enzyme (ALT), glutamic-oxalacetic transaminease (AST), creatinine (Cr), blood glucose (GLU), uric acid (UA), urea nitrogen (BUN) are showed no apparent different Often variation illustrates the harmful effect of the invention without above-mentioned aspect.

6.1.5 obvious adverse reaction is had no during treating.

6.2 functional observation

Change of serum C H0L, TG, HDL-C levels (X ± S) before and after 3 therapeutic test of table

Change of serum C H0L, TG, HDL-C levels (X ± S) before and after 4 therapeutic test of table

Note:* the P ﹤ 0.05 compared with before treatment, # P ﹤ 0.05 compared with the control group.

5 pretherapy and post-treatment change of serum C H0L, TG, HDL-C situation of change of table.

It by table 3-5 as it can be seen that taking a blood sample in half a year twice, respectively treats preceding 1 and treats preceding 2 blood fat data, close taken with the date 2 blood lipid levels are grouped and statistical disposition before the treatment of tested material.Control group and treatment group's change of serum C H0L, TG are horizontal before experiment Compare, no significant difference (P>0.05) it is comparable between, prompting two groups.After treatment group's treatment before CH0L, TG and treatment And compare after control group treatment, difference is significant (P ﹤ 0.05).Pretherapy and post-treatment HDL-C levels are to substantially change (P> 0.05)。

7. conclusion

Using counter point between own control and group, after selecting the volunteer for meeting experimental condition to take tested material 45 days, knot Fruit shows:CH0L, TG are compared with before treatment after taking tested material test group treatment of the present invention, the significant (P of difference<0.05), And decline 10.21%, 20.99% more respectively before CH0L, TG and treatment after treating;After treatment before treatment group CH0L, TG and treatment And compare after control group treatment, the significant (P of difference<0.05);After treatment treatment group HDL-C compared with the control group difference without aobvious Work property (P>0.05).Obvious adverse reaction is had no during treatment.The above clinical study results show, it is possible to determine that the present invention combines Object has hypoglycemic effect.

Claims (5)

1. a kind of Chinese medicine composition for reducing blood glucose, it is characterised in that：Include the substance of following parts by weight:Banaba leaf 60-100 parts of extract, 60-100 parts of faenum graecum seed extract, 60-100 parts of money willow extract, hypoglycemic grass extract 60-100 Part, 60-100 parts of guava leaf extract, 30-60 parts of garlic P.E, 60-130 parts of burdock extract, Corn silk P.E 40-90 parts, 30-90 parts of Shorthorned Epimedium P.E, 60-120 parts of Astragalus Root P.E, 30-60 parts of Cortex Lycii extract, the root bark of white mulberry extraction 30-60 parts of object, 60-120 parts of mulberry-leaf extract, 30-60 parts of Fructus lycii P.E, 30-60 parts of kudzu root extract, Bitter Melon P.E 60-120 parts, 60-120 parts of cinnamomum cassia extract, 20-30 parts of Salvia root P.E, 30-60 parts of Rhizoma Polygonati extract, Semen Coicis extract 20-40 parts, 60-100 parts of Radix Trichosanthis extract, 30-60 parts of Rhizoma Polygonati Odorati extract, 60-120 parts of cornel extractive, rhizoma anemarrhenae extraction 30-60 parts of object;30-80 parts of ginseng, 60-100 parts of spirulina, 60-100 parts of Ramulus euonymi, 15-45 parts of the coptis, radix rehmanniae recen 20-40 Part, 30-60 parts of Schisandra chinensis;2-6 parts of Cr-enriched yeast, 2-4 parts of Se-enriched yeast, 1-3 parts of Zinc-rich saccharomyces cerevisiae, 2-6 parts of magnesium stearate.

2. a kind of preparation method of Chinese medicine composition for reducing blood glucose according to claim 1, it is characterised in that：Step Rapid one, by 30-80 parts of ginseng, 60-100 parts of spirulina, 60-100 parts of Ramulus euonymi, 15-45 parts of the coptis, 20-40 parts of radix rehmanniae recen, five 30-60 parts of taste, cleaning selected with single product, air-dry purification, are respectively crushed into coarse powder, are uniformly mixed, coarse powder mixture is made It is spare;It is divided into three parts;Step 2: first part of coarse powder mixture is put into sealing porcelain, temperature is under 25-30 degree, spontaneous fermentation It 5-7 days, after fermentation, is cleaned and is dried with clear water, obtain dry fermentation coarse powder mixture；Second part of coarse powder mixture pure water It is eluted, the cellulase of the 2-5% of second part of coarse powder total weight of the mixture is added, carry out vibration of ultrasonic wave 20-30 minutes, It is sufficiently stirred, fermentation then is sealed to coarse powder mixture, temperature is fermented 1-3 days under 25-30 degree, after fermentation, carries out 6- 8 cleanings are squeezed, and are dried, are obtained wet fermentation coarse powder mixture；Third part coarse powder mixture carries out naturally dry；First Part, second part and third part mixture are mixed, and mixing coarse powder mixture is obtained；Mixing coarse powder mixture is ground, Obtain ultra micro powder mixture;Step 3: small molecule energy water is added in the ultra micro powder mixture that step 2 is obtained impregnates 60 points Clock is made and impregnates mixture, wherein the weight for the small molecule energy water being added and ginseng, spirulina, Ramulus euonymi, the coptis, Radix Rehmanniae The ratio between yellow, Schisandra chinensis coarse powder mixture total weight is 6:1;Step 4: the mixture that step 3 obtains is placed in the more work(of Chinese medicine It can extract in kettle, open multi-functional extraction kettle power supply and carry out being heated to 100 DEG C, constant temperature lifts 1 hour at this temperature for holding, makes The first extraction mixture is taken, is then filtered, it is spare to obtain first time extracting solution;Step 5: small molecule energy is added into filter residue Water, the weight of the small molecule energy water of addition are 2 with the weight ratio of coarse powder mixture:1, heating extraction, heating temperature 100 DEG C, extraction time is 1 hour, and second of extracting solution is obtained by filtration;Step 6: extracting solution merging twice is placed on triple effect vacuum In high energy evaporation concentrator, it is -0.07MPa to be decompressed to relative pressure, is heated to 80 DEG C, and it is 1.30 that extracting solution, which is condensed into proportion, Medicinal extract, be then dried at 45-50 DEG C, obtain dry extract;Step 7: after dry extract is broken into fine powder, addition bar By 60-100 parts of bar leaf extract, 60-100 parts of faenum graecum seed extract, 60-100 parts of money willow extract, hypoglycemic grass extract 60-100 parts, 60-100 parts of guava leaf extract, 30-60 parts of garlic P.E, 60-130 parts of burdock extract, corn stigma 40-90 parts of extract, 30-90 parts of Shorthorned Epimedium P.E, 60-120 parts of Astragalus Root P.E, 30-60 parts of Cortex Lycii extract, Sang Bai 30-60 parts of bark extract, 60-120 parts of mulberry-leaf extract, 30-60 parts of Fructus lycii P.E, 30-60 parts of kudzu root extract, balsam pear 60-120 parts of extract, 60-120 parts of cinnamomum cassia extract, 20-30 parts of Salvia root P.E, 30-60 parts of Rhizoma Polygonati extract, coix seed 20-40 parts of extract, 30-60 parts of Rhizoma Polygonati Odorati extract, 60-120 parts of cornel extractive, is known 60-100 parts of Radix Trichosanthis extract Female extract 30-60 parts；Add 2-6 parts of Cr-enriched yeast, 2-4 parts of Se-enriched yeast, 1-3 parts of Zinc-rich saccharomyces cerevisiae, magnesium stearate 2-6 Part, after mixing, be packed into snap fit capsule to get:The present invention of every 0.45 gram of weight.

3. a kind of preparation method of Chinese medicine composition for reducing blood glucose according to claim 2, it is characterised in that：Step Coarse granularity in rapid one is 24-50 mesh.

4. a kind of preparation method of Chinese medicine composition for reducing blood glucose according to claim 2, it is characterised in that：Step The granularity of ultra micro powder mixture is at 0.1 μm -10 μm in rapid two.

5. a kind of preparation method of Chinese medicine composition for reducing blood glucose according to claim 2, it is characterised in that：Step Dry extract is broken into 100-150 targeted fine powders in rapid seven.