CN105535679A - Probiotic enzyme ecological-restoration composition - Google Patents
Probiotic enzyme ecological-restoration composition Download PDFInfo
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- CN105535679A CN105535679A CN201511029169.0A CN201511029169A CN105535679A CN 105535679 A CN105535679 A CN 105535679A CN 201511029169 A CN201511029169 A CN 201511029169A CN 105535679 A CN105535679 A CN 105535679A
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- 230000001225 therapeutic effect Effects 0.000 description 1
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- 230000017423 tissue regeneration Effects 0.000 description 1
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Abstract
A probiotic enzyme ecological-restoration composition uses centella asiatica as a main raw material, uses multiple Chinese herbal medicines including angelica sinensis and the like and food materials as auxiliary materials and is prepared by performing aerobic fermentation and anaerobic fermentation, adding filtrate emu oil, badger oil and horse oil and performing homogeneous processing. The probiotic enzyme ecological-restoration composition can expand the intercellular space of the skin, dredge pores and loosen sweat ducts, promotes the skin to absorb a large amount of beneficial nutritional substances in the composition so as to play the special effects of modification, moisture preserving, moisturizing and immunity enhancement, can rapidly repair the skin, has the obvious effect on scalds, wound infection and scar repair and can also serve as a daily skin care products.
Description
Technical field
The present invention relates to technical field of skin care, be specifically related to a kind of probiotic bacteria ferment restoration of the ecosystem compositions, fast and effeciently can repair skin trauma.
Background technology
Skin is the maximum organ of people's bulk area, is also one of most important organ, plays protection organ, resists the intrusion of microorganism and antibacterial etc. in external environment condition, external substance that the adjustment participating in body temperature, perception touch.Skin trauma is generally divided into exopathogenic factor and endogenous cause of ill two aspects.Exopathogenic factor refers to that external influence is in the causative factors of injury of human body.Endogenous cause of ill refers to inside of human body impact and causes the factor of damage, as intrinsic factor such as age, body constitution, topography.Compare in general daily life and common are incised wound, scald, stab.
Skin surface is brick wall structure state, although can play the effect resisting bacterial disease invasion, also counteracts that absorbing nutrient substance simultaneously.Skin ultrastructure is a kind of process of complexity, in this course, different cell, there is complicated relation between cytokine and extracellular matrix.Current clinical medicine, the treatment means of skin injury mainly passes through topical therapeutic.The preparations such as protective agent, antibiotic, vitamin and trace element promote that the effect of wound healing is very limited, because base rests on the stage waiting for wound surface normal healing substantially.Although some somatomedin have the stronger effect promoting wound healing by promoting cell proliferation, but the healing due to wound surface needs multiple somatomedin jointly to participate in, compatibility is complicated, and cell hyperproliferation likely forms hyperplastic scar and even causes canceration, so its safety is the emphasis that people pay close attention to always.
Traditional Chinese medical herbal treatment skin injury is with a long history, for how promoting that wound repair is about unique understanding and rich experience.Chinese medicine external is to promoting that the primary treatment principle of injury repairing is " promoting flow of QI and blood, push away Chen Zhixin, dampness receives pus, evacuation of pus granulation promoting, sour and astringent closing in, promoting tissue regeneration and wound healing ".At present, the external application Chinese medicine that major part is used for the treatment of skin trauma just forms composite for several kinds of Chinese medicinal materials, not through special process.Although these Chinese crude drugs can repair trauma skin, repair time is long, can not reach the effect of repairing fast.
Summary of the invention
The object of the invention is to the defect overcoming above-mentioned prior art, a kind of probiotic bacteria ferment restoration of the ecosystem compositions is provided, adopt composite bacteria several kinds of Chinese medicinal materials is fermented and makes, skin trauma can be repaired fast, comprise scald, stab, wound infection, cicatrix reparation.
For achieving the above object, the present invention adopts following technical scheme:
A kind of probiotic bacteria ferment restoration of the ecosystem compositions, is characterized in that adopting and makes with the following method:
S1, zymocyte liquid prepare: percentage, get pure water 80 ~ 90%, add composite bacteria 2 ~ 8%, then add oligofructose 4 ~ 9%, egg albumen powder 1 ~ 5% is mixed thoroughly, makes zymocyte liquid;
S2: raw material soaking: get Herba Centellae 30 ~ 50 parts, Fructus Fici 5 ~ 10 parts, red Punica granatum L. 5 ~ 10 parts, Folium Rhododendri Simsii 3 ~ 8 parts, the Radix Angelicae Dahuricae 1 ~ 4 part, Radix Salviae Miltiorrhizae 3 ~ 5 parts, fiery sour jujube 3 ~ 5 parts, Radix Ginseng 1 ~ 3 part, Radix Angelicae Sinensis 1 ~ 3 part, Aloe 5 ~ 8 parts, Ramulus et Folium Bauhiniae Faberi 2 ~ 5 parts, Semen Coicis 2 ~ 5 parts, Herba Schizonepetae 0.5 ~ 3 part, Radix Saposhnikoviae 2 ~ 5 parts, 0.5 ~ 2 part, silver ear, Rhizoma Polygoni Cuspidati 1 ~ 3 part, Herba Sedi Linearis 1 ~ 3 part, Radix Ampelopsis 2 ~ 5 parts, 2 ~ 5 parts, Radix Glycyrrhizae, Herba Portulacae 2 ~ 5 parts by weight, add normal-temperature water cleaning, remove impurity, then soak 1-2 days;
S3: raw material sterilizing: the water vapour passing into more than 121 DEG C in the raw material of immersion carries out sterilizing;
S4: be cooled to 30-40 DEG C;
S5: the raw material after sterilizing is inserted fermentation tank, is filled with zymocyte liquid and ferments;
S6: at aerobic conditions lower seal fermentation 8-10 days;
S7: sealing and fermenting 18-25 days under anaerobic;
S8: filter after obtaining filtrate, by weight, add fat of Oromaius norvaehollandeae, the badger seed oil of 0.3-0.5% and the house oil of 0.1-0.3% that weight is filtrate weight 0.1-0.5%, homogenizing process;
Described composite bacteria is photosynthetic bacteria, yeast, Deshi Lactobacillus, Bulgaria's kinds, Lactobacillus bulgaricus, Streptococcus lactis (Lister) Lohnis 1909.554., Lactobacillus fermenti, lactobacillus curvatus, solidify three kinds or more in bacillus cereus, adhesion bacillus cereus, lactobacillus lactis and mix
Preferably, the temperature of sterilizing is 121 DEG C, and the time is 40 ~ 60min.
Preferably, described raw material counts Herba Centellae 40 parts, Fructus Fici 8 parts, red Punica granatum L. 10 parts, Folium Rhododendri Simsii 5 parts, the Radix Angelicae Dahuricae 2 parts, Radix Salviae Miltiorrhizae 3 parts, fiery sour jujube 4 parts, Radix Ginseng 1 part, Radix Angelicae Sinensis 3 parts, Aloe 6 parts, Ramulus et Folium Bauhiniae Faberi 3 parts, Semen Coicis 4 parts, Herba Schizonepetae 1 part, Radix Saposhnikoviae 2 parts, Herba Centellae 1 part, 0.5 part, silver ear, Rhizoma Polygoni Cuspidati 3 parts, Herba Sedi Linearis 2 parts, Radix Ampelopsis 5 parts, 2 points, Radix Glycyrrhizae, Herba Portulacae 4 parts by weight.
Preferably, the charge of zymocyte liquid is to be advisable a little more than raw material surface.
Preferably, during aerobic fermentation, every day passes through 1-3 cubic meter oxygen in fermentation tank, first to fermentation tank aerofluxus at every turn before passing into oxygen.
Preferably, during anaerobic fermentation, every day arranges a gas to fermentation tank.
Present invention also offers containing the external-applied ointment of above-mentioned probiotic bacteria ferment ecological assemblage thing, external plaster, lotion, astringent, protective skin cream, facial treatment milk or facial film
In the present invention, the effect of each raw material is as follows:
Herba Centellae: there is heat-clearing and toxic substances removing, inducing diuresis and reducing edema, nourishing, antiinflammatory, quelling effect, can stimulate deep skin cell to substitute, can compact epidermis and corium coupling part, skin is limbered up, smooth flexible; The Asiaticoside contained, can treat skin ulcer, leprosy.
Fructus Fici: include superoxides, have slow down aging, on the effect that lengthens one's life.
Red Punica granatum L.: there is good toxin expelling, anti-oxidation efficacy.
Folium Rhododendri Simsii: there is curing rheumatism, regulating menstruation and blood, effect that is dry, whitening and speckle dispelling of calming the nerves.
The Radix Angelicae Dahuricae: can improve microcirculation in human body, eliminates pigment excess accumulation, dispels facial colour spot trace trace, the grey pain scabies for the treatment of skin etc.
Radix Gentianae: no matter be for oral administration or external, be all precious beauty treatment superfine product, have effect of whitening and moisturizing simultaneously concurrently.
Radix Ginseng: invigorating primordial QI, tonifying YIN promotes the production of body fluid, and can treat cardiovascular system diseases, diabetes and neurasthenia.
Fire sour jujube: have whitening curative effect, " histamine " can be suppressed to stimulate chromoplast to produce too much melanin, has magical effect of desalination Mai Laning pigment and moisturizing.
Radix Angelicae Sinensis: have antiinflammatory, anticancer, antibacterial, antidotal effect, can scavenging free radicals, improves immunity.
Aloe: be a kind of perennial Liliaceae fleshiness herbaceous plant, containing nutrients such as vitamin A, vitamin B, vitamin C, vitamin Es, can anti-inflammation, moistening skin protection, containing Aloin A, wound hormone and polysaccharide peptide manna, having viral diseases to infect, promote effect that wound healing restores, is the ideal medicament for the treatment of skin injury.
Ramulus et Folium Bauhiniae Faberi: annual vegetation, containing chemical compositions such as flavonoid glycoside, gallic acid, taraxerol, alkaloids, can control eczema, tinea pedis, skin pruritus, has antiallergic, sedation-analgesia, the effect of bringing down a fever.
Semen Coicis: have another name called Semen Coicis, annual sturdy draft, has clearing away heat and discharging pus, skin-care functional.
Herba Schizonepetae: one of conventional medical herbs, antipyretic, can town expectorant, dispel the wind, removing heat from blood.
Radix Saposhnikoviae: there is expelling pathogenic wind from the body surface, removing dampness to relieve pain, effect of relieving convulsion.
Silver ear: replenishing YIN and removing heat, heart tonifying detoxifies, nourishing YIN and moistening the lung.
Rhizoma Polygoni Cuspidati: the effect with heat-clearing and toxic substances removing, eliminating stasis to stop pain, relieving cough and resolving phlegm, can control burn due to hot liquid or fire, traumatic injury.
Herba Sedi Linearis: heat clearing away, detumescence, removing toxic substances.
Radix Ampelopsis: each seed amino acid containing needed by human, and content is higher, the amino acid content especially with special pharmacological effect is high, multivitamin simultaneously containing the needed by human body such as inulin, cellulose, protein, calcium, phosphorus, ferrum and mineral, have defying age and scavenging free radicals and anticancer effect
Radix Glycyrrhizae: have antiinflammatory, anti-allergic effects, can also block the effect of Induced by Carcinogen tumor growth simultaneously.
Herba Portulacae: heat-clearing and toxic substances removing, loose blood detumescence.
Fat of Oromaius norvaehollandeae: have analgesic effect to myalgia.
Badger seed oil: have sterilization, sterilizing function, can promote cell regeneration.
House oil: Glycerin, promotion vis medicatrix naturae and metabolism, resists mottle, alleviates the effect such as dermatitis and scald.
Compared with prior art, the invention has the beneficial effects as follows:
1, compositions of the present invention can skin expansion intercellular substance, dredging pore, and lax antiperspirant pipe, impels the nutritional benefit material in a large amount of absorbing composition of skin, thus plays the special role of amendment, moisturizing, moisturizing, raising immunity.
2, formula for raw stock of the present invention, there is heat-clearing and toxic substances removing, sedation-analgesia, evacuation of pus, viral infection resisting, antiallergic, promote effect that wound healing restores, have skin trauma and repair effect preferably, burn due to hot liquid or fire can be controlled, traumatic injury, simultaneously can also looks improving and the skin nourishing, after the fermentation of composite bacteria, form the microecological environment of a coexistence and co-prosperity, the product made contains multiple ferment, protease, aminoacid, vitamin, there is skin repair, scald and repair, effect that wound infection and cicatrix are repaired, simultaneously can also defying age and scavenging free radicals, can not only as the medicine for external use of skin trauma, can also use as skin care item.
3, product of the present invention is remarkable fast to the repairing effect of skin, as medicinal product and everyday skincare all suitable, can not allergic phenomena be produced.
Detailed description of the invention
Below by specific embodiment the present invention is described in further detail clearly to understand the claimed technical scheme of the present invention.
Embodiment 1
A kind of probiotic bacteria ferment restoration of the ecosystem compositions, it is adopted and makes with the following method:
S1, zymocyte liquid prepare: percentage, get pure water 85%, add composite bacteria 6%, then add oligofructose 6%, egg albumen powder 3% is mixed thoroughly, makes zymocyte liquid; Described compound bacteria is photosynthetic bacteria, yeast, Lactobacillus fermenti, solidify bacillus cereus and count 1:2:1:1 by weight and mix;
S2: raw material soaking: get Herba Centellae 40 parts, Fructus Fici 8 parts, red Punica granatum L. 10 parts, Folium Rhododendri Simsii 5 parts, the Radix Angelicae Dahuricae 2 parts, Radix Salviae Miltiorrhizae 3 parts, fiery sour jujube 4 parts, Radix Ginseng 1 part, Radix Angelicae Sinensis 3 parts, Aloe 6 parts, Ramulus et Folium Bauhiniae Faberi 3 parts, Semen Coicis 4 parts, Herba Schizonepetae 1 part, Radix Saposhnikoviae 2 parts, 0.5 part, silver ear, Rhizoma Polygoni Cuspidati 3 parts, Herba Sedi Linearis 2 parts, Radix Ampelopsis 5 parts, 2 points, Radix Glycyrrhizae, Herba Portulacae 4 parts by weight, add normal-temperature water cleaning, remove impurity, then soak 1 day;
S3: raw material sterilizing: the water vapour passing into more than 121 DEG C in the raw material of immersion carries out sterilizing;
S4: be cooled to 30-40 DEG C;
S5: the raw material after sterilizing is inserted fermentation tank, is filled with zymocyte liquid until do not have 2 centimetres, raw material surface to ferment;
S6: ferment 10 days at aerobic conditions lower seal, passes into 2 cubic metres of oxygen after arranging a gas every day;
S7: sealing and fermenting 25 days under anaerobic, arranges a gas every day;
S8: filter after obtaining filtrate, by weight, add fat of Oromaius norvaehollandeae, the badger seed oil of 0.4% and the house oil of 0.3% that weight is filtrate weight 0.2%, homogenizing process.
Embodiment 2
A kind of probiotic bacteria ferment restoration of the ecosystem compositions, it is adopted and makes with the following method:
S1, zymocyte liquid prepare: percentage, get pure water 80%, add composite bacteria 8%, then add oligofructose 7%, egg albumen powder 5% is mixed thoroughly, makes zymocyte liquid; The ratio mixing that described compound bacteria is photosynthetic bacteria, yeast, adhesion bacillus cereus, lactobacillus lactis count 1:2:1:1 by weight;
S2: raw material soaking: get by weight Herba Centellae 50 parts, Fructus Fici 5 parts, red Punica granatum L. 8 parts, Folium Rhododendri Simsii 8 parts, the Radix Angelicae Dahuricae 1 part, Radix Salviae Miltiorrhizae 4 parts, fiery sour jujube 3 parts, Radix Ginseng 2 parts, Radix Angelicae Sinensis 1 part, Aloe 5 parts, Ramulus et Folium Bauhiniae Faberi 5 parts, Semen Coicis 2 parts, Herba Schizonepetae 3 parts, Radix Saposhnikoviae 4 parts, 1.5 parts, silver ear, Rhizoma Polygoni Cuspidati 2 parts, Herba Sedi Linearis 1 part, Radix Ampelopsis 3 parts, 5 points, Radix Glycyrrhizae, Herba Portulacae 2 parts, add normal-temperature water cleaning, remove impurity, then soak 2 days;
S3: raw material sterilizing: the water vapour passing into more than 121 DEG C in the raw material of immersion carries out sterilizing;
S4: be cooled to 30-40 DEG C;
S5: the raw material after sterilizing is inserted fermentation tank, is filled with zymocyte liquid until do not have 2 centimetres, raw material surface to ferment;
S6: ferment 8 days at aerobic conditions lower seal, passes into 3 cubic metres of oxygen after arranging a gas every day;
S7: sealing and fermenting 18 days under anaerobic, arranges a gas every day;
S8: filter after obtaining filtrate, by weight, add fat of Oromaius norvaehollandeae, the badger seed oil of 0.5% and the house oil of 0.1% that weight is filtrate weight 0.1%, homogenizing process.
Embodiment 3
A kind of probiotic bacteria ferment restoration of the ecosystem compositions, it is adopted and makes with the following method:
S1, zymocyte liquid prepare: percentage, get pure water 90%, add composite bacteria 8%, then add oligofructose 4%, egg albumen powder 6% is mixed thoroughly, makes zymocyte liquid; Described composite bacteria is photosynthetic bacteria, yeast, Deshi Lactobacillus, Lactobacillus bulgaricus, Streptococcus lactis (Lister) Lohnis 1909.554. mix;
S2: raw material soaking: get Herba Centellae 30 parts, Fructus Fici 10 parts, red Punica granatum L. 5 parts, Folium Rhododendri Simsii 3 parts, the Radix Angelicae Dahuricae 4 parts, Radix Salviae Miltiorrhizae 5 parts, fiery sour jujube 5 parts, Radix Ginseng 3 parts, Radix Angelicae Sinensis 2 parts, Aloe 8 parts, Ramulus et Folium Bauhiniae Faberi 2 parts, Semen Coicis 5 parts, Herba Schizonepetae 0.5 part, Radix Saposhnikoviae 5 parts, 2 parts, silver ear, Rhizoma Polygoni Cuspidati 1 part, Herba Sedi Linearis 3 parts, Radix Ampelopsis 2 parts, 3.5 points, Radix Glycyrrhizae, Herba Portulacae 5 parts by weight, add normal-temperature water cleaning, remove impurity, then soak 3 days;
S3: raw material sterilizing: the water vapour passing into more than 121 DEG C in the raw material of immersion carries out sterilizing;
S4: be cooled to 30-40 DEG C;
S5: the raw material after sterilizing is inserted fermentation tank, is filled with zymocyte liquid until do not have 2 centimetres, raw material surface to ferment;
S6: ferment 8 days at aerobic conditions lower seal, passes into 3 cubic metres of oxygen after arranging a gas every day;
S7: sealing and fermenting 20 days under anaerobic, arranges a gas every day;
S8: filter after obtaining filtrate, by weight, add fat of Oromaius norvaehollandeae, the badger seed oil of 0.3% and the house oil of 0.2% that weight is filtrate weight 0.3%, homogenizing process.
Embodiment 4 skin scald Experiment on therapy
One, experimental technique: get healthy adult ICR mice 20, after injecting anesthetic, lose hair or feathers in back place, depilation place is 1cm × 1cm, after back is scalded, be divided into blank group and experimental group at random, often organize 10 mices, the not administration of blank group, experimental group to be coated with 3 embodiments 1 obtained ecology amendment compositions every day, observation scabs time and the rate that scabs, and records result.
Two, experimental result
For a person skilled in the art, according to technical scheme described above and design, other various corresponding change and distortion can be made, and all these change and distortion all should belong within the protection domain of the claims in the present invention.
Claims (7)
1. a probiotic bacteria ferment restoration of the ecosystem compositions, is characterized in that adopting and makes with the following method:
S1, zymocyte liquid prepare: percentage, get pure water 80 ~ 90%, add composite bacteria 2 ~ 8%, then add oligofructose 4 ~ 9%, egg albumen powder 1 ~ 5% is mixed thoroughly, makes zymocyte liquid;
S2: raw material soaking: get by weight Herba Centellae 30 ~ 50 parts, Fructus Fici 5 ~ 10 parts, red Punica granatum L. 5 ~ 10 parts, Folium Rhododendri Simsii 3 ~ 8 parts, the Radix Angelicae Dahuricae 1 ~ 4 part, Radix Salviae Miltiorrhizae 3 ~ 5 parts, fiery sour jujube 3 ~ 5 parts, Radix Ginseng 1 ~ 3 part, Radix Angelicae Sinensis 1 ~ 3 part, Aloe 5 ~ 8 parts, Ramulus et Folium Bauhiniae Faberi 2 ~ 5 parts, Semen Coicis 2 ~ 5 parts, Herba Schizonepetae 0.5 ~ 3 part, Radix Saposhnikoviae 2 ~ 5 parts, 0.5 ~ 2 part, silver ear, Rhizoma Polygoni Cuspidati 1 ~ 3 part, Herba Sedi Linearis 1 ~ 3 part, Radix Ampelopsis 2 ~ 5 parts, 2 ~ 5 parts, Radix Glycyrrhizae, Herba Portulacae 2 ~ 5 parts, add normal-temperature water cleaning, remove impurity, then soak 1-2 days;
S3: raw material sterilizing: the water vapour passing into more than 121 DEG C in the raw material of immersion carries out sterilizing;
S4: be cooled to 30-40 DEG C;
S5: the raw material after sterilizing is inserted fermentation tank, is filled with zymocyte liquid and ferments;
S6: at aerobic conditions lower seal fermentation 8-10 days;
S7: sealing and fermenting 18-25 days under anaerobic;
S8: filter after obtaining filtrate, by weight, add fat of Oromaius norvaehollandeae, the badger seed oil of 0.3-0.5% and the house oil of 0.1-0.3% that weight is filtrate weight 0.1-0.5%, homogenizing process;
Described composite bacteria is photosynthetic bacteria, yeast, Deshi Lactobacillus, Bulgaria's kinds, Lactobacillus bulgaricus, Streptococcus lactis (Lister) Lohnis 1909.554., Lactobacillus fermenti, lactobacillus curvatus, solidify three kinds or more in bacillus cereus, adhesion bacillus cereus, lactobacillus lactis and mix.
2. probiotic bacteria ferment restoration of the ecosystem compositions as claimed in claim 1, is characterized in that: the temperature of sterilizing is 121 DEG C, and the time is 40 ~ 60min.
3. probiotic bacteria ferment restoration of the ecosystem compositions as claimed in claim 1, is characterized in that: described raw material counts Herba Centellae 40 parts, Fructus Fici 8 parts, red Punica granatum L. 10 parts, Folium Rhododendri Simsii 5 parts, the Radix Angelicae Dahuricae 2 parts, Radix Salviae Miltiorrhizae 3 parts, fiery sour jujube 4 parts, Radix Ginseng 1 part, Radix Angelicae Sinensis 3 parts, Aloe 6 parts, Ramulus et Folium Bauhiniae Faberi 3 parts, Semen Coicis 4 parts, Herba Schizonepetae 1 part, Radix Saposhnikoviae 2 parts, Herba Centellae 1 part, 0.5 part, silver ear, Rhizoma Polygoni Cuspidati 3 parts, Herba Sedi Linearis 2 parts, Radix Ampelopsis 5 parts, 2 points, Radix Glycyrrhizae, Herba Portulacae 4 parts by weight.
4. probiotic bacteria ferment restoration of the ecosystem compositions as claimed in claim 1, is characterized in that: the charge of zymocyte liquid is to be advisable a little more than raw material surface.
5. probiotic bacteria ferment restoration of the ecosystem compositions as claimed in claim 1, is characterized in that: during aerobic fermentation, and every day passes through 1-3 cubic meter oxygen in fermentation tank, first to fermentation tank aerofluxus at every turn before passing into oxygen.
6. probiotic bacteria ferment restoration of the ecosystem compositions as claimed in claim 1, is characterized in that: during anaerobic fermentation, every day arranges a gas to fermentation tank.
7. contain the external-applied ointment of the probiotic bacteria ferment restoration of the ecosystem compositions described in claim 1 to 6 any one, external plaster, lotion, astringent, protective skin cream, facial treatment milk or facial film.
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