Summary of the invention
Technical problem to be solved by this invention is to provide a kind of effective, the safe and reliable Chinese medicine composition for skin whitening.
Technical problem to be solved by this invention realizes by the following technical solutions:
For a Chinese medicine composition for skin whitening, be made up of the crude drug of following weight,
Colla Corii Asini 19-21 gram, Arillus Longan 14-16 gram, Fructus Citri Limoniae 19-21 gram, Semen Coicis 19-21 gram, Radix Scutellariae 14-16 gram, Fructus Lycii 14-16 gram, Fructus Crataegi 19-21 gram, Semen Persicae 11-13 gram, Rhizoma Dioscoreae 14-16 gram, Fructus Mori 14-16 gram, Exocarpium Citri Rubrum 11-13 gram, Rhizoma Polygonati 14-16 gram, Fructus Jujubae 19-21 gram.
Preferred weight part of each crude drug is:
20 grams, Colla Corii Asini, Arillus Longan 15 grams, 20 grams, Fructus Citri Limoniae, Semen Coicis 20 grams, Radix Scutellariae 15 grams, Fructus Lycii 15 grams, Fructus Crataegi 20 grams, 12 grams, Semen Persicae, Rhizoma Dioscoreae 15 grams, Fructus Mori 15 grams, Exocarpium Citri Rubrum 12 grams, Rhizoma Polygonati 15 grams, 20 grams, Fructus Jujubae.
Crude drug used by the present invention can be bought from common Chinese shop and obtain, and its specification meets national Chinese crude drug standard.
Another object of the present invention is to provide a kind of method preparing the present composition, comprises the steps,
1) each taste crude drug is taken by weight described in prescription;
2) by above-mentioned each taste crude drug pulverization, incapsulate.
1, pharmacology analysis:
Colla Corii Asini: YIN nourishing of enriching blood, moisturizes, hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.
Arillus Longan: invigorating the heart and spleen, nourishing blood to tranquillize the mind.For insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion.
Fructus Citri Limoniae: sour in the mouth is sweet, property is flat, enters liver, stomach warp.There is preventing phlegm from forming and stopping coughing, promote the production of body fluid, effect of spleen invigorating.
Semen Coicis: correction gas, sharp the intestines and stomach, detumescence, removes pathogen in the heart.
Radix Scutellariae: heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.
Fructus Lycii: conditioner body immunity function, can effectively Tumor suppression growth and cell mutation, there is the effect of the aspects such as slow down aging, anti-fatty liver, adjusting blood lipid and blood glucose.
Fructus Crataegi: the immunity of enhancing body, has anti-aging, anticancer effect.
Semen Persicae: blood stasis removing and clots absorbing; Moisturize laxation.
Rhizoma Dioscoreae: sweet, flat.Strengthening the spleen and stomach, lung benefiting kidney, tonify deficiency are won.
Fructus Mori: nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Having a dizzy spell of main deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.
Exocarpium Citri Rubrum: cold expelling, dampness, promoting the circulation of QI, expectorant.
Rhizoma Polygonati: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.
Fructus Jujubae: there is the effects such as tonify deficiency QI invigorating, nourishing blood to tranquillize the mind, invigorating the spleen and regulating the stomach.
2, usage and consumption:
The dosage of medicine of the present invention depends on concrete dosage form, and the factor such as the age of patient, body weight, health status.
Instruction: each 6, every day 3 times, the morning, noon and afternoon take, and a course for the treatment of is 1 month.
3, the present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and disease therapy, drops into the use link of disease therapy provide science and objective foundation to this medicine.
Its test method and result of the test are distinguished as follows:
1) animal acute toxicity test is carried out to capsule prepared by the present invention:
Medicine: the crude drug used by the present invention is bought from common Chinese shop and obtained, and its specification meets national Chinese crude drug standard.
Experimental animal: white mice, body weight is at about 50g, and male and female Stochastic choice, is bought by market.
Method and result: get white mice 30, hungry 20 hours, feeding 50g by filling with several times every every day, feeding one week continuously, observing 10 days, and mice is movable normal, non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical medicine dose safety.
2) long-term toxicity test for animals is carried out to capsule prepared by the present invention:
Experimental animal: rat, body weight is at 120-130g, and male and female Stochastic choice, is bought by market.
Method and result: get rat 20, be divided into 2 groups, often organize 10, wherein the 1st group as administration group, 40-50g is fed by filling with several times every every day, 2nd group of diet as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without significant change with matched group, equal non-toxic reaction, a kind of safe drugs.
4, diagnostic criteria
1) clinical diagnosis: face has chloasma in various degree, xerosis cutis, easily ftracture, senile plaque, freckle, the symptoms such as pigmentation.
2) in order to verify clinical efficacy, this prescription is tried out in Jieshou City, Anhui Province First People's Hospital respectively, and random selecting is 50 routine female patients wherein.
3) Therapeutic Method: take capsule of the present invention, divides for each person every day and takes for three times, one time 6, take 1 month continuously.
4) efficacy determination:
Recovery from illness: mottle all disappears, skin smooth, seamless.
Effective: mottle disappears more than 80%.
Effective: mottle disappears more than 10%, and part colours is thin out.
Invalid: the symptoms such as mottle are unchanged or worsen.
Concrete therapeutic outcome is see table 1;
Table 1
Number of cases |
Recovery from illness |
Effective |
Effectively |
Invalid |
Effective percentage (%) |
50 |
10 |
20 |
19 |
1 |
98 |
5, points for attention:
1. diet should be light, gives up alcohol and pungent, raw and cold, greasy food.
2. child, women breast-feeding their children, elderly and infirm should take under doctor instructs.
3. driver, work high above the ground person are cautious use of.
4. strictly take by usage and dosage.
5. pair this medicine and alcohol intolerance person forbidding, allergic constitution person be cautious use of.
6. prohibit the use when this property of drug changes.
7. please this medicine is placed on the place that child can not contact.
8. as used other medicines, please Ref Dr or pharmacist before using this medicine.
The invention has the beneficial effects as follows: the present invention is formed by multiple prepared from traditional Chinese medicines, can dredging the meridian, benefiting qi and nourishing blood blood stasis dispelling, invigorating kidney, promoting blood circulation, reinforce insufficiency and reduce excessiveness, soothing the liverly to repose, dynamic equilibrium is carried out to internal organs entirety, reverse endocrine regulation, improve hemorheology index, take good care of combination, there is taking convenience, feature that drug cost is low.
Detailed description of the invention
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
Each crude drug is taken: 20 grams, Colla Corii Asini, Arillus Longan 15 grams, 20 grams, Fructus Citri Limoniae, Semen Coicis 20 grams, Radix Scutellariae 15 grams, Fructus Lycii 15 grams, Fructus Crataegi 20 grams, 12 grams, Semen Persicae, Rhizoma Dioscoreae 15 grams, Fructus Mori 15 grams, Exocarpium Citri Rubrum 12 grams, Rhizoma Polygonati 15 grams, 20 grams, Fructus Jujubae by following weight.By above-mentioned each taste crude drug pulverization, be prepared into capsule according to a conventional method.
Embodiment 2
Each crude drug is taken: 21 grams, Colla Corii Asini, Arillus Longan 16 grams, 21 grams, Fructus Citri Limoniae, Semen Coicis 21 grams, Radix Scutellariae 16 grams, Fructus Lycii 16 grams, Fructus Crataegi 21 grams, 13 grams, Semen Persicae, Rhizoma Dioscoreae 16 grams, Fructus Mori 16 grams, Exocarpium Citri Rubrum 13 grams, Rhizoma Polygonati 16 grams, 21 grams, Fructus Jujubae by following weight.By above-mentioned each taste crude drug pulverization, be prepared into capsule according to a conventional method.
Embodiment 3
Each crude drug is taken: 19 grams, Colla Corii Asini, Arillus Longan 14 grams, 19 grams, Fructus Citri Limoniae, Semen Coicis 19 grams, Radix Scutellariae 14 grams, Fructus Lycii 14 grams, Fructus Crataegi 19 grams, 11 grams, Semen Persicae, Rhizoma Dioscoreae 14 grams, Fructus Mori 14 grams, Exocarpium Citri Rubrum 11 grams, Rhizoma Polygonati 14 grams, 19 grams, Fructus Jujubae by following weight.By above-mentioned each taste crude drug pulverization, be prepared into capsule according to a conventional method.
Model case:
Case 1
Scheme certain, female, 28 years old.Because of working principle, every day is all in the face of computer, causes face dry, although every day is all at use skin-protection product, effect is always not good.After take capsule of the present invention, after 4 courses for the treatment of, effect manifests, skin become glossy, pale, flexible.
Case 2
Side so-and-so, female, 40 years old.There is chloasma in face, is concerned with face, no conscious sympton.Take capsule of the present invention 2 months chloasma to disappear, face lubrication is glossy.
Case 3
Thank certain, female, 38 years old.Live in rural area, often need dry farm work, xerosis cutis, pigmentation, easy bursting by freezing in winter.After taking 4 courses for the treatment of of capsule of the present invention, xerosis cutis problem is effectively solved, after taken again 8 courses for the treatment of continuously, moisture of skin is better, and follow up a case by regular visits to 1 year, bursting by freezing phenomenon does not appear in winter.
Case 4
Huang, female, 32 years old.Face is long has freckle for many years, the black Huang of skin, and used a lot of speckle dispelling product, effect is undesirable, and take 4 courses for the treatment of of capsule of the present invention, freckle disappears, and blee bleaches.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.