CN105434237B - Cosmetic composition containing durian extract - Google Patents
Cosmetic composition containing durian extract Download PDFInfo
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- CN105434237B CN105434237B CN201510902930.0A CN201510902930A CN105434237B CN 105434237 B CN105434237 B CN 105434237B CN 201510902930 A CN201510902930 A CN 201510902930A CN 105434237 B CN105434237 B CN 105434237B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention discloses a kind of cosmetic composition containing durian extract.The cosmetic composition count by weight percentage, includes following components：Durian pulp extract 0.001%~10%, emulsifying agent 1.0~6.0%, thickener 0.4~0.8%, emollient 17.0~27.0%, preservative 0.6~1.6% and balance deionized water.Durian extract contains the material to skin beneficiating such as vitamin C, vitamin E (tocopherol), selenium.Cosmetic composition containing durian pulp extract is mitigating Skin pigmentation, is mitigating skin oxidative and stress work well with wrinkle of skin is reduced, and because of itself fragrance of durian pulp extract, without adding essence in cosmetic composition, reduce the anaphylactogen of skin.
Description
Technical field
The present invention relates to a kind of cosmetic composition containing plant extracts, contains durian pulp more particularly to one kind
The cosmetic composition of extract, belongs to personal-care supplies technical field.
Background technology
Durian, also known as nephelium lappaceum, linsang fruit, golden pillow.Durian is one of famous fruit in the torrid zone, originates in Malaysia.East
Some country's plantations of South Asia are more, wherein most with Thailand.Also there is plantation in Zhong states Guang Dong ﹑ Hainan.Durian contains abundant albumen
In addition matter, fat, carbohydrate and cellulose also contain vitamin A, vitamin B, vitamin C, vitamin E (tocopherol),
Folic acid, nicotinic acid, niacin, palmitic acid, arachidic acid, palmitolic acid, inorganic elements calcium, iron, phosphorus, potassium, sodium, magnesium, selenium etc., nutrition is close
Degree is high and balanced, has the laudatory title of " king of fruit ".
Vitamin C is also known as ascorbic acid, is considered safety by dermatologist earliest and can make the oral of color spot desalination
Medicine, is famous antioxidant, has positive effect to removing posteriority melanocyte deposition, and with anti-oxidant and removing free radical
Effect.
Vitamin E (tocopherol) has skin protective effect, protects the unrighted acid in cell membrane in light, heat and spoke
It is not oxidized under the conditions of penetrating, to prevent the accumulation of abnormal, hair wrinkle and lipofuscin from can simultaneously improve microcirculation.
Selenium is the important component of glutathione peroxidase, its main Physiological Function is by glutathione peroxidating
The form of thing enzyme, plays antioxidation to prevent lipid peroxidation, so as to delay the formation of lipofuscin.Selenium can also improve human body
Immune function, by suppress radical reaction influence cross-linking process, so as to play the effect of anti-aging.
In recent years, as the raising of people's living standard and aesthetical standard, more and more people pursue the tender careful flesh of water
Skin.It is by preventing the loss of moisture in skin and absorbing in external environment and moisturizing is the most important link of skin care
Moisture keeps moisture of skin to improve the elastic and smooth of skin to achieve the purpose that to keep to contain certain moisture in skin
Degree, is to ensure skin health, the important measures of anti-aging.The stream of the idea such as " Chinese prescription ", " advocating nature ", " subtraction skin care "
OK, the research and development of plant source skin-protecting factor are made there is great realistic meaning.
In fact, the durian as food is the outstanding source of vitamin and mineral, when durian pulp extract by with
When skin, its effect can be diverted directly to skin.Therefore, durian pulp extract is as a kind of new cosmetics
Additive also has realistic meaning.
The content of the invention
The object of the present invention is to provide a kind of cosmetic composition containing durian extract, which has
Mitigate Skin pigmentation and the excellent effect for improving skin elasticity and reducing wrinkle of skin.
To achieve these goals, a kind of cosmetic composition for including durian extract of present invention offer, by weight hundred
Divide than calculating, include following components：Durian pulp extract 0.001%~10%, emulsifying agent 1.0~6.0%, thickener 0.4
~0.8%, emollient 17.0~27.0%, preservative 0.6~1.6% and deionized water surplus.
The cosmetic composition of the present invention, the content range of the durian pulp extract is 1%~8%.
The present invention cosmetic composition, the durian pulp extract be using durian pulp as raw material, through solvent extraction,
Concentration, then by spray drying, obtained powdered durian extract.
The cosmetic composition of the present invention, the preparation process of the durian extract comprise the following steps：
1) pre-treatment：Durian is peeled off, remove seed, take durian pulp to be extracted；
2) extract：Durian pulp is placed in 8 times of amount deionized waters and is extracted 2 times in 60 DEG C, is stirred frequently in extraction process,
When being heated to keeping temperature 2 small after seething with excitement, extraction feed liquid for the first time is collected, extracts the deionized waters for adding 5 times of amounts for the second time,
When ebuillition of heated insulation 2 is small, second of extraction feed liquid is collected；
3) filter：Extracting solution is filtered by centrifuge；
4) concentrate：Extracting solution after filtering is imported in inspissator and is concentrated under reduced pressure, temperature control is below 60 DEG C, very
Reciprocal of duty cycle is controlled in more than 0.06MPa, and it is 1.21~1.26 or so to be concentrated into density, that is, is concentrated into the 1/5- of original extracting liquid volume
1/3, obtain pasta durian extracting solution；
5) it is spray-dried：Pasta durian extracting solution is again by spray drying, 160~200 DEG C of intake air temperature, air outlet
80~110 DEG C of temperature, obtains powdered durian extract.
The cosmetic composition of the present invention, the emulsifying agent are alkyl glycosides series, high-carbon fatty alcohol polyoxyethylene ether system
Row, polyethylene glycol stearate, ethoxylated methyl glucose glucosides stearate, polyoxyethylene sorbitan monostearate
Series, sucrose fatty ester, fatty glyceride, lecithin, anhydrous sorbitol mono fatty acid ester, fatty acid citrate acid glyceride
One or both of it is mixed above.
The cosmetic composition of the present invention, the thickener is polyacrylate and polyacrylamide copolymer, polypropylene
Hydrochlorate and polyacrylamide dimethyltaurate copolymer, hydroxy ethyl methacrylate and acrylic acid dimethyltaurate copolymerization
One or both of thing, xanthans, cellulose, hyaluronic acid are mixed above.
The present invention cosmetic composition, the emollient for macadimia nut oil, shea butter, dimethicone, flash
Bar oil, lanolin, Isoeicosane, white oil, vaseline, avocado oil, glycerine, 1,3-BDO, apricot kernel oil, pentaerythrite four are stearic
Two or more mixing in acid esters, high-carbon fatty alcohol, carbonic acid dioctyl ester.
The cosmetic composition of the present invention, the preservative is Phenoxyethanol and Sensiva SC50 compound, fragrant fresh ketone,
Two or more mixing in methylisothiazolinone and polyalcohol, nipagin esters series, iodo propinyl butyl carbamate.
The cosmetic composition containing durian extract of the present invention has the following technical effect that：
1st, the present inventor has been carried out largely studying on durian pulp extract to the effect of skin, knot
Fruit shows that durian pulp extract has mitigation Skin pigmentation, mitigation skin oxidative stress be with the effect of reduction wrinkle of skin
Fruit, so as to fulfill the present invention.
2nd, cosmetic composition of the invention contains durian pulp extract, and said composition can mitigate skin pigment and sink
Product, the antioxidation activity for improving skin and the effect with excellent raising skin elasticity and reduction wrinkle of skin.
3rd, because of itself fragrance of durian pulp extract, without adding essence in cosmetic composition, skin is reduced
Anaphylactogen.
Embodiment
Below by specific embodiment, the present invention is further explained, but these embodiments are used only for that it is described in more detail
With, and be not applied to limit the present invention in any form.
1st, the preparation method of durian extract
The durian extract used in the present invention is using durian pulp as raw material, through solvent extraction, concentration, then by spraying
It is dry, obtained powdered durian extract.Specific step is：
1) pre-treatment：Durian is peeled off, remove seed, take durian pulp to be extracted.
2) extract：Durian pulp is placed in 8 times of amount deionized waters and is extracted 2 times in 60 DEG C, is stirred frequently in extraction process,
When being heated to keeping temperature 2 small after seething with excitement, extraction feed liquid for the first time is collected, extracts the deionized waters for adding 5 times of amounts for the second time,
When ebuillition of heated insulation 2 is small, second of extraction feed liquid is collected.
3) filter：Extracting solution is filtered by centrifuge.
4) concentrate：Extracting solution after filtering is imported in inspissator and is concentrated under reduced pressure, temperature control is below 60 DEG C, very
Reciprocal of duty cycle is controlled in more than 0.06MPa, and it is 1.21~1.26 or so to be concentrated into density, that is, is concentrated into the 1/5- of original extracting liquid volume
1/3, obtain pasta durian extracting solution.
5) it is spray-dried：Pasta durian extracting solution is again by spray drying, 160~200 DEG C of intake air temperature, air outlet
80~110 DEG C of temperature, obtains powdered durian extract.
2nd, durian extract suppresses melanogenesis effect test method and its result.
Using above-mentioned durian extract as test specimen, measure in accordance with the following methods, evaluate melanogenesis inhibition.
1) addition of cell inoculation, substances
Murine melanoma cells B16 is inoculated in 6 orifice plates with 100,000 cells/wells.Second day, addition substances were molten
Liquid (solvent is DMSO in the case of dried object).
2) cell proliferation test
Attract within 3 days to remove culture medium afterwards in addition substances solution, then addition is containing 10% alma indigo plant solution
EMEM culture medium 1ml, make its reaction at 37 DEG C.100 μ l are moved into 96 orifice plates after 30 minutes, in excitation wavelength 544nm, measure
Fluorescence is measured under conditions of wavelength 590nm.Relative value using the value as cell number, the group for calculating addition substances are opposite
In the cell percentage (% cell numbers) for the group (only adding solvent) for being not added with substances.% cell numbers are higher, then mean
Cytotoxicity is lower, will be less than 80% and is judged as " toxic ".
3) measure of melanocyte amount
Attract to remove culture medium, washed using buffer solution (phosphate buffer 50mM, pH 6.8), then add 1M NaOH
Cell is dissolved, measures the absorbance of 475nm.Relative value using the value as melanocyte amount, calculates the group phase of addition substances
Melanocyte amount ratio (%) for the group (only adding solvent) for being not added with substances.Melanocyte amount ratio is lower, then means black
Element generation inhibition is higher.
Will using each plant extracts melanocyte amount ratio (%) the results are shown in table 1.Table 1 is using the melanocyte amount of control as base
Standard, is represented with the melanocyte amount of addition durian extract relative to the percentage of control.Only with the addition of without durian extract
Solvent situation for control.
Table 1 uses the result of the melanocyte amount ratio (%) of the durian extract of various concentrations
As shown in Table 1, the durian extract used in the present invention has excellent melanocyte inhibitory action, can mitigate skin-color
Element deposition.
The durian extract of the present invention can be used in the cosmetic compositions such as toner, lotion, cream, be not particularly limited agent
Type.
Embodiment 1
A kind of Essence or surfactant that with the addition of durian pulp extract, the raw material and each original of the Essence or surfactant
The percentage by weight of material is：
Preparation process is as follows：
1st, first hydroxyethyl cellulose, Sodium Hyaluronate, durian extract are dissolved in propane diols and 1,3 butylene glycol；2、
Glycerine and deionized water are added, stirring is warming up to 80-85 DEG C, insulated and stirred 20-30min；
3rd, continue to stir 30-45min after being cooled to 45 DEG C of addition preservatives.
Embodiment 2
The percentage by weight of a kind of lotion that with the addition of durian pulp extract, the raw material of the lotion and each raw material is：
Preparation process is as follows：
1st, water phase configuration：First Sodium Hyaluronate, durian extract, xanthans are dissolved in propane diols, add glycerine,
Dipropylene glycol, EDTA-2Na, allantoin, deionized water stirring are warming up to 80-85 DEG C, and dissolving is complete, continues insulated and stirred 20-
30min；
2nd, oil phase configures：16/octadecyl alcolol, high-carbon fatty alcohol glucan emulsifying agent, PEG-100 stearates and list is sweet
The mixture of ester, monoglyceride, isomery hexadecane hydrocarbon, caprylic capric glyceryl ester, dimethicone stirring are warming up to 80-85 DEG C,
Dissolving is complete, insulated and stirred 20-30min；
3rd, at 80-85 DEG C, oil phase is added into water phase stirring and emulsifying 5-10min, then with homogenizer in 10000-15000rpm
Homogeneous 3-5min, then it is slowly added to polyacrylate and polyacrylamide dimethyltaurate in 3000-5000rpm homogeneous
Copolymer, continues in 10000-15000rpm homogeneous 1-2min；
4th, slow cooling adds preservative to less than 45 DEG C, continues to stir 30-45min.
Embodiment 3
The percentage by weight of a kind of cream that with the addition of durian pulp extract, the raw material of the cream and each raw material is：
Preparation process is as follows：
1st, water phase configuration：First Sodium Hyaluronate, durian extract, xanthans are dissolved in propane diols, add glycerine,
Allantoin, deionized water stirring are warming up to 80-85 DEG C, and dissolving is complete, continues insulated and stirred 20-30min；
2nd, oil phase configures：16/octadecyl alcolol, high-carbon fatty alcohol glucan emulsifying agent, PEG-100 stearates and list is sweet
The mixture of ester, monoglyceride, isomery hexadecane hydrocarbon, caprylic capric glyceryl ester, dimethicone stirring are warming up to 80-85 DEG C,
Dissolving is complete, insulated and stirred 20-30min；
3rd, at 80-85 DEG C, oil phase is added into water phase stirring and emulsifying 5-10min, then with homogenizer in 10000-15000rpm
Homogeneous 3-5min, then it is slowly added to polyacrylate and polyacrylamide dimethyltaurate in 3000-5000rpm homogeneous
Copolymer, continues in 10000-15000rpm homogeneous 1-2min；
4th, slow cooling adds preservative to less than 45 DEG C, continues to stir 30-45min.
2nd, senile-resistant efficacy is tested
2.1 test method：
Volunteer requires：40~50 years old age, each half of male and female, without any skin disease and skin allergy history, from
It is willing to participate in experiment, signature informed consent form, cannot use any cosmetics in 2 days before test, during experiment must not make before testing
With any cosmetics beyond test sample.Subject is with after warm water cleaning face, and face uses embodiment 1 or embodiment on one side
2 or embodiment 3 skin care item (being selected according to skin properties) once in the morning and once at night, try out 8 weeks.Control cream is used in another half of face
Frost.
2.2 evaluation criterion：
Trier, which changes autologous skin, to be evaluated；(German CK is public by graphical analysis instrument VISIA for medical practitioner
Master of ceremonies's device) front and rear face-image contrast is tried out trier, provide evaluation.
2.3 evaluation result：
98% trier has been evaluated as autologous skin larger improvement, specially has light using the face of this skin care item
Pool, wrinkle of skin have improvement.Medical practitioner is evaluated, and 90% trier's facial wrinkles have improvement, and skin shine improves, skin
What is become is smooth, and anti-aging effects are more apparent.
Result above proves：Skin care item of the invention containing durian extract, can be effectively improved skin shine, improve wrinkle
Line, delay skin aging.
The above described is only a preferred embodiment of the present invention, not make limitation in any form to the present invention, therefore
It is every without departing from technical solution of the present invention content, what the technical spirit according to the present invention made above example any simply repaiies
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (7)
1. a kind of cosmetic composition containing durian extract, it is characterised in that be by with the following group count by weight percentage
Divide and be made：Durian pulp extract 0.001%~10%, emulsifying agent 1.0~6.0%, thickener 0.4~0.8%, emollient
17.0~27.0%, preservative 0.6~1.6% and deionized water surplus；The durian pulp extract be using durian pulp as
Raw material, through solvent extraction, concentration, then by spray drying, obtained powdered durian extract；The system of the durian extract
Standby technique specifically includes following steps：
1) pre-treatment：Durian is peeled off, remove seed, take durian pulp to be extracted；
2) extract：Durian pulp is placed in 8 times of amount deionized waters and is extracted 2 times in 60 DEG C, stirs, heats frequently in extraction process
When keeping temperature 2 small after to boiling, extraction feed liquid for the first time is collected, second of extraction adds the deionized water of 5 times of amounts, heating
When boiling insulation 2 is small, second of extraction feed liquid is collected；
3) filter：Extracting solution is filtered by centrifuge；
4) concentrate：Extracting solution after filtering is imported in inspissator and is concentrated under reduced pressure, temperature control is below 60 DEG C, vacuum
Control in more than 0.06MPa, it is 1.21~1.26 to be concentrated into density, that is, is concentrated into the 1/5-1/3 of original extracting liquid volume, obtains
Pasta durian extracting solution；
5) it is spray-dried：Pasta durian extracting solution is again by spray drying, 160~200 DEG C of intake air temperature, air outlet temperature
80~110 DEG C, obtain powdered durian extract.
2. cosmetic composition according to claim 1, it is characterised in that：The content range of the durian pulp extract
1%~8%.
3. cosmetic composition according to claim 1, it is characterised in that：The emulsifying agent is alkyl glycosides series, height
Carbon fatty alcohol polyoxyethylene ether series, polyethylene glycol stearate, ethoxylated methyl glucose glucosides stearate, polyoxyethylene
Sorbitan monostearate series, sucrose fatty ester, fatty glyceride, lecithin, anhydrous sorbitol mono fatty acid
One or both of ester, fatty acid citrate acid glyceride are mixed above.
4. cosmetic composition according to claim 1, it is characterised in that：The thickener is polyacrylate and poly- third
Acrylamide copolymer, polyacrylate and polyacrylamide dimethyltaurate copolymer, hydroxy ethyl methacrylate and propylene
One or both of sour dimethyltaurate copolymer, xanthans, cellulose, hyaluronic acid are mixed above.
5. cosmetic composition according to claim 1, it is characterised in that：The emollient is macadimia nut oil, breast wood
Fruit oil, dimethicone, jojoba oil, lanolin, Isoeicosane, white oil, vaseline, avocado oil, glycerine, 1,3-BDO,
Two or more mixing in apricot kernel oil, pentaerythritol tetrastearate, high-carbon fatty alcohol, carbonic acid dioctyl ester.
6. cosmetic composition according to claim 1, it is characterised in that：The preservative is Phenoxyethanol and ethyl hexyl
Base glycerol compound, fragrant fresh ketone, methylisothiazolinone and polyalcohol, nipagin esters series, iodo propinyl fourth methyl carbamic
Two or more mixing in ester.
7. cosmetic composition according to claim 1, it is characterised in that：Its formulation is selected from toner, lotion, cream.
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| CN201510902930.0A CN105434237B (en) | 2015-12-09 | 2015-12-09 | Cosmetic composition containing durian extract |
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| CN201510902930.0A CN105434237B (en) | 2015-12-09 | 2015-12-09 | Cosmetic composition containing durian extract |
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| CN105434237A CN105434237A (en) | 2016-03-30 |
| CN105434237B true CN105434237B (en) | 2018-05-01 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111135128A (en) * | 2020-01-20 | 2020-05-12 | 名臣健康用品股份有限公司 | A cosmetic composition containing pineapple peel extract and its preparation method |
| CN112336651A (en) * | 2020-12-10 | 2021-02-09 | 广州市柏菲化妆品有限公司 | Hejoba moisturizing membrane and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101433500A (en) * | 2008-12-08 | 2009-05-20 | 广东名臣有限公司 | Low-viscosity skin lotion and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20070042064A1 (en) * | 2005-08-19 | 2007-02-22 | Access Business Group International Llc | Extracts of durian fruit for use in skin care compositions |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101433500A (en) * | 2008-12-08 | 2009-05-20 | 广东名臣有限公司 | Low-viscosity skin lotion and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 《Antioxidative Activity of the Durian Extract》;Yun Sun Ji et.al.;《Korean Journal of Medicinal Crop Science》;20131231;第21卷(第4期);第258-259页Table 3-4 * |
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Effective date of registration: 20221026 Address after: 515834 Liannan Industrial Zone, Chenghai District, Shantou City, Guangdong Province Patentee after: Guangdong Mingchen Daily Chemical Co.,Ltd. Address before: 515834 Liannan Industrial Zone, Lianxia Town, Chenghai District, Shantou City, Guangdong Province Patentee before: MINGCHEN HEALTH Co.,Ltd. |
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