CN105343148A - Eye care preparation - Google Patents
Eye care preparation Download PDFInfo
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- CN105343148A CN105343148A CN201510749387.5A CN201510749387A CN105343148A CN 105343148 A CN105343148 A CN 105343148A CN 201510749387 A CN201510749387 A CN 201510749387A CN 105343148 A CN105343148 A CN 105343148A
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- eye
- eye care
- care preparation
- preparation
- eye health
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses an eye care preparation. The invention aims at providing an eye care preparation which is stable in property, strong in adaptability, significant in effect and is convenient to prepare and use. Functional components of the eye care preparation disclosed by the invention consist of the following ingredients in parts by weight: 2400-3600 parts of semen momordicae oil, 0.9-1.1 parts of astaxanthin, 0.9-1.1 parts of coenzyme Q-10 and 0.9-1.1 parts of a selenium-enriched yeast. By virtue of the special functional component, namely the semen momordicae oil which is rich in beta-carotene, the eye care preparation disclosed by the invention can supplement eye nutrition fundamentally, so that purposes of relieving and repairing are achieved; meanwhile, on the basis of a synergistic effect among the various raw materials, the eye care preparation is quite strong in antioxidant activity, and is easy to be absorbed by a human body and capable of eliminating free radicals timely so as to keep eye activity; and upon experiments, the eye care preparation is quite significant in eye care effect.
Description
Technical field
The invention belongs to food and field of health care products, particularly a kind of eye health preparation.
Background technology
Modern gets used to using computer for a long time, but computer radiate can cause health generation peroxidization.The people worked before computer of being everlasting is not only the harm being subject to radiation, and eyes also can often feel dry and astringent pain simultaneously, and eyeball is unglazed, little moisture loss god.Ocular tissue constantly produces free radical in physiological activity, more with eye, and eyes are more tired, and the free radical of generation is more.If people stares at a target for a long time, as seen computer, reading etc., the persistent period is oversize, and winking reflex is fewer, will cause a dry tack free, causes asthenopia symptom.
At present, on market, the product of alleviating asthenopia mostly is outer Tropfen.But outer Tropfen can only of short duration fatigue alleviating symptom, needs repeatedly to use, cannot solve eyestrain problem from source, and groups of people can have instillation mode and repel sense, and liquid medicine also can exist excitement to eyeball.For this reason, someone investigated the edible preparation for eye health, the Chinese patent being 201510186355.9 as application number discloses a kind of eye care preparation and preparation method thereof, the main component of preparation is lutein ester, zeaxanthin and astaxanthin, makes granule, capsule or tablet after adopting embedded material to embed with microcapsule embedded method; The main composition of said preparation is lutein ester, therefore obvious to the improvement effectiveness comparison of initial stage senile degeneration of macula (AMD) patient, but to alleviating eyestrain of general population, and the functions of prevention and health care of myopia and other ophthalmics is not given prominence to.Application number is the health care soft capsule that the Chinese patent of 201410801491.X discloses a kind of alleviating asthenopia, it is made up of flexible glue utricule and the content be encapsulated in flexible glue utricule, flexible glue utricule by gelatin, glycerol, water routinely ratio make, content is made up of yeast rich in selenium, astaxanthin, Pericarpium Citri tangerinae extract, phylloxanthin, Concha Ostreae powder, VB1, Margarita powder, Semen Lini oil and adjuvant; Content complicated component in this soft capsule, easily causes the reduction of the compatibility between composition and ingredient stability, thus cannot reach the health-care effect of expection.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, provide a kind of character to stablize, the suitability is strong, Be very effective and manufacturing and a kind of eye health preparation easy to use.
In order to achieve the above object, a kind of eye health preparation of the present invention, the functional component of preparation comprises following component by weight:
Semen Momordicae aril breakdown 2400-3600 part
Astaxanthin 0.9-1.1 part
Coenzyme q-10 0.9-1.1 part
Yeast rich in selenium 0.9-1.1 part
As preferably, the functional component of described eye health preparation comprises following component by weight:
Semen Momordicae aril breakdown 3000 parts
Astaxanthin 1 part
Coenzyme q-10 1 part
Yeast rich in selenium 1 part
As preferably, also comprise phylloxanthin in the functional component of described eye health preparation, its weight portion is 90-110 part.
As preferably, described eye health preparation is soft capsule preparation, and the functional component of preparation is encapsulated in the utricule of soft capsule, produces the eye health soft capsule that functional component content is 100mg ~ 200mg/ grain.
Semen Momordicae aril breakdown is the seed envelopes extract of Semen Momordicae fruit.The beta-carotene of very high content is rich in Semen Momordicae aril breakdown; beta-carotene is the provitamin A that people find to protect eyes best at present; because it can be converted into vitamin A in human body; and vitamin A can protect eye retina and crystalline lens not by " free radical " infringement; the lubrication of protection cornea and transparency; promote eye health, wear contact lens for long-term or watch nutrient important especially the people of computer screen for a long time attentively.Content beta-carotene in Semen Momordicae fruit oil is more than 2 times of spirulina, is more than 20 times of Radix Dauci Sativae.By take in beta-carotene can protect eyes, alleviate the symptom of dry and astringent pain, and prevent old after xerophthalmia and cataract.
Astaxanthin is the antioxidant that the suppression absorption of human body free radical ability that finds at nature of the mankind is the strongest up to now.Astaxanthin has much important physiology and the biological functions such as antioxidation, antitumor, enhancing immunity, its biology oxidation resistance than the strong 100-500 of vitamin E doubly, stronger than carotene more than 10 times.Astaxanthin can increase the blood flow of retinal capillary; the retina cell that remarkable minimizing causes because of high intraocular pressure is withered; protect pregnable tyrosine residue and crystallin from the infringement of oxidative stress simultaneously, and delay crystallin precipitation and cataract to a certain extent.
High-quality protein in yeast rich in selenium is the effective ingredient that composition looks quality, and the catalysis of selenium energy also eliminates the free radical material harmful to eyes, thus the cell membrane of protection eyes;
Coenzyme q-10 has active cell vigor, promotes that cell is from collagenogenic effect.Astaxanthin and coenzyme q-10 belong to fat soluble nutrient, and fat soluble nutrient has higher human absorptivity.
Special efficacy composition Semen Momordicae aril breakdown in the present invention, owing to being rich in beta-carotene, can fundamentally increase eye nutrition, reaches the object alleviated and repair.Meanwhile, various raw material Synergistic, has very strong antioxidant activity, and is easily absorbed by the body, and energy is scavenging free radicals in time, keeps eye vigor, and through experiment, the effect of eye health is very remarkable.Eye health formulation components of the present invention is natural, reasonable mixture ratio, dimensionally stable, and raw material is oxidation Decomposition not easily, can ensure that the abundant absorption of human body and eye improve the lasting maintenance of effect.
Detailed description of the invention
Embodiment 1
A kind of eye health preparation, it is made up of flexible glue utricule and the functional component be encapsulated in flexible glue utricule,
Containing 150.15mg functional component, wherein Semen Momordicae aril breakdown 150mg, astaxanthin 0.05mg, coenzyme q-10 0.05mg and yeast rich in selenium 0.05mg in every soft capsule.
Embodiment 2
A kind of eye health preparation, it is made up of flexible glue utricule and the functional component be encapsulated in flexible glue utricule,
Containing 133.48mg functional component, wherein Semen Momordicae aril breakdown 133.33mg, astaxanthin 0.05mg, coenzyme q-10 0.05mg and yeast rich in selenium 0.05mg in every soft capsule.
Embodiment 3
A kind of eye health preparation, it is made up of flexible glue utricule and the functional component be encapsulated in flexible glue utricule,
Containing 163.79mg functional component, wherein Semen Momordicae aril breakdown 163.64mg, astaxanthin 0.05mg, coenzyme q-10 0.05mg and yeast rich in selenium 0.05mg in every soft capsule.
Embodiment 4
A kind of eye health preparation, it is made up of flexible glue utricule and the functional component be encapsulated in flexible glue utricule,
Containing 155.15mg functional component, wherein Semen Momordicae aril breakdown 150mg, phylloxanthin 5mg, astaxanthin 0.05mg, coenzyme q-10 0.05mg and yeast rich in selenium 0.05mg in every soft capsule.
Usage of the present invention and consumption are: by human body recommended intake be: each 1-2 grain.
Carry out human experimentation with the eye health preparation given by embodiment 1 below, further illustrate effect that the present invention has eye health.
1, subjects and method:
Tested material: with the eye health preparation given by embodiment 1 for given the test agent.
Study subject: select the age be 20-30 year, test group, matched group each 60 example.Test group is divided into test one group and test two groups, often organizes 30 examples; Matched group is divided into contrast one group and contrast two groups, often organizes 30 examples.
Method of testing: arrange two groups of test group and matched group simultaneously to watch the same film play by computer screen continuously, record starts to occur the time of ophthalmic uncomfortable symptom and various Symptoms, as ophthalmalgia, the symptom such as eye is dry, eye is puckery, ophthalmic bloated, blurred vision; After starting to occur ophthalmic uncomfortable symptom, take tested material respectively to test group, take placebo to matched group, tested material and placebo are each 1; Test one group and contrast one group to take after tested material and placebo and continue to observe various Symptoms; Test two groups and contrast two groups is tested the symptom taken before and after tested material and placebo respectively and improved effect and duration of photopic vision.
2, result of the test:
(1) result of the test of a group and contrast one group is tested:
Test one group of ophthalmic uncomfortable symptom all starting after 2 hours to occur in various degree at continuous viewing film with contrast one group; Test one group take tested material after about 15 minutes various symptom all have and alleviate in various degree, in ensuing viewing process, wherein again not there is ophthalmic uncomfortable symptom in 12 examples in 3 hours, and wherein 18 examples did not again occur ophthalmic uncomfortable symptom in 5 hours; And contrasting one group in ensuing viewing process, 30 examples all continue sensation ophthalmic uncomfortable.
(2) result of the test of two groups and contrast two groups is tested:
1. symptom improves effective percentage: it is that symptom improves number of cases/test-meal number of cases × 100 that symptom improves effective percentage (%) computational methods.Comprise that eye is ached, ophthalmic bloated, photophobia, blurred vision, eye are dry and astringent, foreign body sensation, to shed tears, general malaise 8 kinds of symptoms.
Table 1: test two groups of symptoms and improve effective percentage
Table 2: contrast two groups of symptoms and improve effective percentage
2. duration of photopic vision change is compared
Test two groups of durations of photopic vision and rise to 0.82 ± 0.14 after test-meal by 0.65 ± 0.13 before test-meal, improve 0.17 ± 0.13, difference has statistical significance (P < 0.01); Test two groups of durations of photopic vision (0.82 ± 0.14) after test-meal and contrast two groups (0.66 ± 0.14) and compare and have statistical significance (P < 0.01).
3, result judges
(1) compare between test group with matched group group, symptom is effectively improved;
(2) compare between test group with matched group group, duration of photopic vision difference has significance (P < 0.01), and average duration of photopic vision raising is more than or equal to 10%;
Therefore can judge that this tested material has eye health function; In the process of lasting eye, can significantly improve ophthalmic uncomfortable symptom at short notice by taking eye health preparation of the present invention, and the retention time that symptom improves effect can continue 3-5 hour, being extended between making just to commonly use at the moment.
Claims (4)
1. an eye health preparation, is characterized in that: the functional component of described eye health preparation comprises following component by weight:
Semen Momordicae aril breakdown 2400-3600 part
Astaxanthin 0.9-1.1 part
Coenzyme q-10 0.9-1.1 part
Yeast rich in selenium 0.9-1.1 part.
2. a kind of eye health preparation according to claim 1, is characterized in that: the functional component of described eye health preparation comprises following component by weight:
Semen Momordicae aril breakdown 3000 parts
Astaxanthin 1 part
Coenzyme q-10 1 part
Yeast rich in selenium 1 part.
3. a kind of eye health preparation according to claim 1, it is characterized in that: also comprise phylloxanthin in the functional component of described eye health preparation, its weight portion is 90-110 part.
4. a kind of eye health preparation according to claim 1 or 3, it is characterized in that: described eye health preparation is soft capsule preparation, the functional component of preparation is encapsulated in the utricule of soft capsule, produces the eye health soft capsule that functional component content is 100mg ~ 200mg/ grain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510749387.5A CN105343148A (en) | 2015-11-06 | 2015-11-06 | Eye care preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510749387.5A CN105343148A (en) | 2015-11-06 | 2015-11-06 | Eye care preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105343148A true CN105343148A (en) | 2016-02-24 |
Family
ID=55319308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510749387.5A Pending CN105343148A (en) | 2015-11-06 | 2015-11-06 | Eye care preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105343148A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101243875A (en) * | 2008-03-24 | 2008-08-20 | 北京维尼康生物技术有限公司 | Health care preparation rich in xanthophyll and beta-carotene and preparation method |
| CN104474018A (en) * | 2014-12-22 | 2015-04-01 | 威海百合生物技术股份有限公司 | Health-care soft capsule for relieving asthenopia |
| CN104839688A (en) * | 2015-04-20 | 2015-08-19 | 华北制药秦皇岛有限公司 | Eye care preparation and preparation method thereof |
-
2015
- 2015-11-06 CN CN201510749387.5A patent/CN105343148A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101243875A (en) * | 2008-03-24 | 2008-08-20 | 北京维尼康生物技术有限公司 | Health care preparation rich in xanthophyll and beta-carotene and preparation method |
| CN104474018A (en) * | 2014-12-22 | 2015-04-01 | 威海百合生物技术股份有限公司 | Health-care soft capsule for relieving asthenopia |
| CN104839688A (en) * | 2015-04-20 | 2015-08-19 | 华北制药秦皇岛有限公司 | Eye care preparation and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 杨永青 等: "杨永青 等", 《食品科学》 * |
| 马莉: "《维生素保健康全书》", 31 May 2013, 天津科学技术出版社 * |
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Application publication date: 20160224 |