CN104397311A - Blueberry composite tablet candy capable of relieving visual fatigue and preparation method thereof - Google Patents
Blueberry composite tablet candy capable of relieving visual fatigue and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a blueberry composite tablet candy capable of relieving visual fatigue and a preparation method thereof. The blueberry composite tablet candy capable of relieving the visual fatigue comprises the following raw materials in percentage by weight: 13.25 percent of a blueberry extract, 0.5 percent of lutein esters, 0.3 percent of beta-carotene, 1.0 percent of citric acid, 64.45 percent of sorbitol, 2 percent of xylooligosaccharide, 3 percent of dextrin and 15 percent of microcrystalline cellulose, wherein the blueberry extract is extracted from a mixture of blackberry pomace dry matter and acid ethanol; the acid ethanol comprises ethanol and water with the volume percentage of 60 percent; the pH value of the acid ethanol is 1.5 to 3.0; the blackberry pomace dry matter and the acid ethanol are in the mass volume ratio of 1:50-1:70; the preparation method of the blueberry composite tablet candy capable of relieving the visual fatigue comprises the following main steps: 1, preparing the blueberry extract; 2, crushing; 3, mixing; 4, granulating; 5, tabletting; 6 packaging. The blueberry composite tablet candy capable of relieving the visual fatigue can effectively relieve the visual fatigue, can improve eyesight after long-term eating, and is convenient to take; a new using way is provided for utilizing fresh blueberry and fully playing intentional physiological and pharmacological efficacies.
Description
Technical field
the present invention relates to food processing technology field, particularly a kind of blueberry compound pressed candy and preparation method thereof of alleviating asthenopia.
Background technology
visual fatigue is also known as kopiopia, and main manifestations is vision disorder, during as close eye, occurs capable overlapping, the word jump of eye-blurred, ghost image, word; See near after when seeing again at a distance, need to see clearly gradually a moment.Eye symptom have eye sleepy, keep in dark place, eyelid is heavy, sour swollen sense or pain around difficulty in opening the eyes, eyeball and eye socket, shed tears, foreign body sensation, eye are dry and astringent, saccade etc.Serious visual fatigue patient also has constitutional symptom in various degree, as headache, dizzy, unable, n and V etc.
visual fatigue dependent illness in eye, but based on patient's subjective symptoms, the syndrome that eye or whole body apparatus factors and psychologic factors are interweaved, is also often called as kopiopia syndrome.Outside environmental elements causes asthenopic major reason, and as illumination is not enough or excessively strong, distribution of light sources is uneven or glimpse, and fixation object is too small, meticulous or unstable.In addition, some illness in eye and systemic disease also can cause asthenopic generation, and everybody should enhance your vigilance.
except kopiopia, eye is dry and astringent, foreign body sensation, eyelid sense of heaviness, blurred vision, photophobia are shed tears, eye distending pain and eye are congested, visual fatigue also may cause more obstinate headache, giddy, nauseating, One's spirits are drooping, absent minded, decrease of memory, poor appetite, and the symptom such as neck shoulder aching pain in waist and back and articulations digitorum manus numbness; Also can there is diplopia, stereoscopic vision dysfunction, intraocular pressure rising, corneal injury etc. in minority; There are glaucoma, eye surface or other eye disease patients also can cause or increase the weight of original illness in eye because of " visual fatigue "; In addition, visual fatigue also may cause the reduction of early ageing and body immunity.
there are medicine or the health products of various alleviating asthenopia in the market, but containing toxin or with side effect in most drug, and a kind of snacks that candy is people to be liked, but candy is in the market only based on sour-sweet taste, help be there is no to the health of human body, and sometimes candy is overeated the also illness such as easy induced Diabetic, decayed tooth.Therefore, blueberry compound pressed candy market being badly in need of a kind of candy with health role, particularly a kind of alleviating asthenopia and preparation method thereof.
Summary of the invention
blueberry compound pressed candy that the object of this invention is to provide a kind of alleviating asthenopia and preparation method thereof.
object of the present invention is achieved through the following technical solutions: blueberry compound pressed candy of a kind of alleviating asthenopia and preparation method thereof, raw materials by weight, blueberry extract 13.25%, lutein ester 0.5%, beta carotene 0.3%, citric acid 1.0%, D-sorbite 64.45%, xylo-oligosaccharide 2%, dextrin 3%, microcrystalline cellulose 15%, described blueberry extract is by blueberry pomace dry, extract after the mixing of acid ethanol, described sour ethanol: the volume fraction of ethanol and water is 60%, pH value is 1.5-3.0, described blueberry pomace dry and the mass volume ratio of sour ethanol are 1:50-1:70.
blueberry compound pressed candy of described a kind of alleviating asthenopia and preparation method thereof, by preferred weight number, be made up of blueberry extract 10 parts, lutein ester 0.5 part, beta carotene 0.3 part, citric acid 1.0 parts, D-sorbite 67.7 parts, xylo-oligosaccharide 2 parts, 3 parts, dextrin, microcrystalline cellulose 15 parts.
blueberry compound pressed candy of described a kind of alleviating asthenopia and preparation method thereof, by preferred weight number, blueberry extract 13.25 parts, lutein ester 0.5 part, beta carotene 0.3 part, citric acid 1.0 parts, D-sorbite 64.45 parts, xylo-oligosaccharide 2 parts, 3 parts, dextrin, microcrystalline cellulose 15 parts are made.
blueberry compound pressed candy of described a kind of alleviating asthenopia and preparation method thereof, by preferred weight number, blueberry extract 15 parts, lutein ester 0.5 part, beta carotene 0.3 part, citric acid 1.0 parts, D-sorbite 62.7 parts, xylo-oligosaccharide 2 parts, 3 parts, dextrin, microcrystalline cellulose 15 parts are made.
blueberry compound pressed candy of described a kind of alleviating asthenopia and preparation method thereof, the key step of its preparation method is:
the preparation of step 1, blueberry extract: blueberry pomace dry is mixed with sour ethanol, employing ultrasonic assistant extracts, the power that ultrasonic assistant extracts is 350W, Extracting temperature is 35-45 DEG C, extraction time is 45-50 minute, then extract is carried out spraying dry, obtain the powdery blueberry extract containing anthocyanin;
step 2, pulverizing: blueberry extract, lutein ester, beta carotene, citric acid, D-sorbite, xylo-oligosaccharide, dextrin, microcrystalline cellulose pulverizer are pulverized, cross 60 mesh sieves after pulverizing, for subsequent use;
step 3, mixing: by weight percentage, choose the blueberry extract after pulverizing and sieving, lutein ester, beta carotene, citric acid, D-sorbite, xylo-oligosaccharide, dextrin, microcrystalline cellulose, put into mixer and mix, obtain compound;
step 4, granulation: the 65% food grade alcohol of compound containing PVP is adopted Boiling Fuel Injection Spray granulation technique softwood, oscillating granulator is put into after softwood makes, cross 14 order nylon mesh to granulate, then dry, dried particle is again put into oscillating granulator and is carried out whole grain, crosses 60 mesh sieves;
step 5, compressing tablet: by the particle made, carry out compressing tablet with ZP35B rotary tablet machine, in tablet 0.5 gram/piece;
step 6, packaging: the tablet after compressing tablet is packed, the blueberry compound pressed candy of obtained a kind of alleviating asthenopia.
in candy raw material: blueberry, formal name used at school cowberry, belongs to Ericaceae genus vaccinium plant.Fruit is in blue, and drape layer white fruit powder, pulp is fine and smooth, and fruity is sour-sweet, unique flavor, nutritious.Containing particular matters such as multiple anthocyanin, natural visual purple, flavonoids and phenolic acid in Blueberry; experiment shows; anthocyanin is obtained by Sephadex LH-20 post and the separation and purification of column chromatography for separation gathering system; and identify 13 kinds of anthocyanin by HPLC-MS, be respectively the glucosides thing of cyanidin (Cy), delphinidin (Dp), paeonidin (Pn), morning glory pigment (Pt) and malvidin (Mv) and glucose, galactolipin or arabinose.Anthocyanin in blueberry can improve eyesight, it is dizzy to alleviate; Protection capillary, promotes to look regeneration of erythrocytes, strengthens the adaptive capacity to dark; Improve night vision, improve dark adaptation ability.But fresh fruit can not be preserved for a long time, and blueberry fresh fruit is no exception, and anthocyanidin is heavy very easily oxidized at air as a kind of antioxidant, thus loses value.
lutein ester has important protective effect to the macula lutea in retina, easily causes macular degeneration and eye-blurred during shortage. and then there is vision degeneration, the symptoms such as myopia.Lutein ester is the precursor of VA, can be converted into VA in human body.The main Physiological Function of lutein ester to eyes is as antioxidant and photoprotection. optic nerve is non-renewable, is very easily subject to the injury of harmful free radicals, and the antioxidation of lutein ester can suppress the formation of harmful free radicals.The a large amount of blue light of lutein ester Absorbable rod, wavelength and the ultraviolet light of blue visible light are close, to reach the maximum a kind of light of potential hazard in amphiblestroid visible ray. before arriving cell responsive on retina, light first through the highest accumulation regions of lutein, if at this moment just this injury can be reduced to minimum depending on the lutein content at macula lutea place is abundant.
beta carotene is the retinol precursor forming visual pigment in retinal photoreceptor, eyes are when experiencing light and shade and the color change of light, constantly will consume retinol, if used up retinol can not get enough in time supplementing, the adaptation adaptability to changes causing eyes to the light and shade of light and color change is reduced, so long-term, also will cause blind.Beta carotene can promote the synthesis of retinol, the various diseases such as in addition, beta carotene also has anti-photosensitive dermatitis, delays senility, radiation proof, anticancer and prevention cardiovascular and cerebrovascular diseases.Changing into dimolecular vitamin A under the effect of beta carotene enzyme in vivo, be the important sources of vitamin A, and vitamin A effectively can improve eyesight, alleviating asthenopia.Research shows, take examination trencherman containing beta carotene for control group, eye be swollen, ophthalmodynia, photophobia, eye-blurred, dry and astringent symptom be improved significantly.
beneficial effect of the present invention: the blueberry compound pressed candy of a kind of alleviating asthenopia of the present invention, can effective alleviating asthenopia, long-term eating can improve eyesight, taking convenience of the present invention, for blueberry fresh fruit utilization and give full play to its physiology of having a mind to, pharmacological effect provides a kind of new occupation mode.
the present invention is through two groups of clinical verifications, and wherein one group is that treatment group takes the present invention, takes the present invention every day once, within 7 days, be a course for the treatment of, another group control group uses eyedrops, and every day uses once, it within 7 days, is a course for the treatment of, every group selection outpatient 110 example, wherein man 40 example, female 70 example, max age 75 years old, minimal ages 35 years old, clinical manifestation is red eye, swell pain, hot eyes is dim-sighted, eye is swollen, ophthalmodynia, photophobia, eye-blurred, eyes are dry and astringent, and table one is for taking the contrasting data after the course for the treatment of:
table 1 is taken front and back and is compared (unit: people) two groups of courses for the treatment of
there were significant differences for treatment group and control group, thus can find out that the present invention's application clinically has significant curative effect.
Detailed description of the invention
embodiment 1
blueberry compound pressed candy of a kind of alleviating asthenopia and preparation method thereof, raw materials by weight, blueberry extract 13.25%, lutein ester 0.5%, beta carotene 0.3%, citric acid 1.0%, D-sorbite 64.45%, xylo-oligosaccharide 2%, dextrin 3%, microcrystalline cellulose 15%, described blueberry extract is extracted after being mixed by blueberry pomace dry, sour ethanol, described sour ethanol: the volume fraction of ethanol and water is 60%, pH value is 1.5-3.0, and described blueberry pomace dry and the mass volume ratio of sour ethanol are 1:50-1:70.
embodiment 2
blueberry compound pressed candy of a kind of alleviating asthenopia and preparation method thereof, by preferred weight number, be made up of blueberry extract 10 parts, lutein ester 0.5 part, beta carotene 0.3 part, citric acid 1.0 parts, D-sorbite 67.7 parts, xylo-oligosaccharide 2 parts, 3 parts, dextrin, microcrystalline cellulose 15 parts.
embodiment 3
blueberry compound pressed candy of a kind of alleviating asthenopia and preparation method thereof, by preferred weight number, blueberry extract 13.25 parts, lutein ester 0.5 part, beta carotene 0.3 part, citric acid 1.0 parts, D-sorbite 64.45 parts, xylo-oligosaccharide 2 parts, 3 parts, dextrin, microcrystalline cellulose 15 parts are made.
embodiment 4
blueberry compound pressed candy of a kind of alleviating asthenopia and preparation method thereof, by preferred weight number, blueberry extract 15 parts, lutein ester 0.5 part, beta carotene 0.3 part, citric acid 1.0 parts, D-sorbite 62.7 parts, xylo-oligosaccharide 2 parts, 3 parts, dextrin, microcrystalline cellulose 15 parts are made.
embodiment 5
blueberry compound pressed candy of a kind of alleviating asthenopia and preparation method thereof, the key step of its preparation method is:
the preparation of step 1, blueberry extract: blueberry pomace dry is mixed with sour ethanol, employing ultrasonic assistant extracts, the power that ultrasonic assistant extracts is 350W, Extracting temperature is 35-45 DEG C, extraction time is 45-50 minute, then extract is carried out spraying dry, obtain the powdery blueberry extract containing anthocyanin;
step 2, pulverizing: blueberry extract, lutein ester, beta carotene, citric acid, D-sorbite, xylo-oligosaccharide, dextrin, microcrystalline cellulose pulverizer are pulverized, cross 60 mesh sieves after pulverizing, for subsequent use;
step 3, mixing: by weight percentage, choose the blueberry extract after pulverizing and sieving, lutein ester, beta carotene, citric acid, D-sorbite, xylo-oligosaccharide, dextrin, microcrystalline cellulose, put into mixer and mix, obtain compound;
step 4, granulation: the 65% food grade alcohol of compound containing PVP is adopted Boiling Fuel Injection Spray granulation technique softwood, oscillating granulator is put into after softwood makes, cross 14 order nylon mesh to granulate, then dry, dried particle is again put into oscillating granulator and is carried out whole grain, crosses 60 mesh sieves;
step 5, compressing tablet: by the particle made, carry out compressing tablet with ZP35B rotary tablet machine, in tablet 0.5 gram/piece;
step 6, packaging: the tablet after compressing tablet is packed, the blueberry compound pressed candy of obtained a kind of alleviating asthenopia.
Claims (5)
1. the blueberry compound pressed candy and preparation method thereof of an alleviating asthenopia, it is characterized in that: raw materials by weight, blueberry extract 13.25%, lutein ester 0.5%, beta carotene 0.3%, citric acid 1.0%, D-sorbite 64.45%, xylo-oligosaccharide 2%, dextrin 3%, microcrystalline cellulose 15%, described blueberry extract is extracted after being mixed by blueberry pomace dry, sour ethanol, described sour ethanol: the volume fraction of ethanol and water is 60%, pH value is 1.5-3.0, and described blueberry pomace dry and the mass volume ratio of sour ethanol are 1:50-1:70.
2. the blueberry compound pressed candy and preparation method thereof of a kind of alleviating asthenopia according to claim 1, it is characterized in that: by preferred weight number, be made up of blueberry extract 10 parts, lutein ester 0.5 part, beta carotene 0.3 part, citric acid 1.0 parts, D-sorbite 67.7 parts, xylo-oligosaccharide 2 parts, 3 parts, dextrin, microcrystalline cellulose 15 parts.
3. the blueberry compound pressed candy and preparation method thereof of a kind of alleviating asthenopia according to claim 1, it is characterized in that: by preferred weight number, blueberry extract 13.25 parts, lutein ester 0.5 part, beta carotene 0.3 part, citric acid 1.0 parts, D-sorbite 64.45 parts, xylo-oligosaccharide 2 parts, 3 parts, dextrin, microcrystalline cellulose 15 parts are made.
4. the blueberry compound pressed candy and preparation method thereof of a kind of alleviating asthenopia according to claim 1, it is characterized in that: by preferred weight number, blueberry extract 15 parts, lutein ester 0.5 part, beta carotene 0.3 part, citric acid 1.0 parts, D-sorbite 62.7 parts, xylo-oligosaccharide 2 parts, 3 parts, dextrin, microcrystalline cellulose 15 parts are made.
5. the blueberry compound pressed candy and preparation method thereof of a kind of alleviating asthenopia according to claim 1, is characterized in that: the key step of its preparation method is:
The preparation of step 1, blueberry extract: blueberry pomace dry is mixed with sour ethanol, employing ultrasonic assistant extracts, the power that ultrasonic assistant extracts is 350W, Extracting temperature is 35-45 DEG C, extraction time is 45-50 minute, then extract is carried out spraying dry, obtain the powdery blueberry extract containing anthocyanin;
Step 2, pulverizing: blueberry extract, lutein ester, beta carotene, citric acid, D-sorbite, xylo-oligosaccharide, dextrin, microcrystalline cellulose pulverizer are pulverized, cross 60 mesh sieves after pulverizing, for subsequent use;
Step 3, mixing: by weight percentage, choose the blueberry extract after pulverizing and sieving, lutein ester, beta carotene, citric acid, D-sorbite, xylo-oligosaccharide, dextrin, microcrystalline cellulose, put into mixer and mix, obtain compound;
Step 4, granulation: the 65% food grade alcohol of compound containing PVP is adopted Boiling Fuel Injection Spray granulation technique softwood, oscillating granulator is put into after softwood makes, cross 14 order nylon mesh to granulate, then dry, dried particle is again put into oscillating granulator and is carried out whole grain, crosses 60 mesh sieves;
Step 5, compressing tablet: by the particle made, carry out compressing tablet with ZP35B rotary tablet machine, in tablet 0.5 gram/piece;
Step 6, packaging: the tablet after compressing tablet is packed, the blueberry compound pressed candy of obtained a kind of alleviating asthenopia.
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Application publication date: 20150311 |