CN105232669A - 一种酸枣叶黄酮提取物及其制备方法和应用 - Google Patents
一种酸枣叶黄酮提取物及其制备方法和应用 Download PDFInfo
- Publication number
- CN105232669A CN105232669A CN201510747487.4A CN201510747487A CN105232669A CN 105232669 A CN105232669 A CN 105232669A CN 201510747487 A CN201510747487 A CN 201510747487A CN 105232669 A CN105232669 A CN 105232669A
- Authority
- CN
- China
- Prior art keywords
- ziziphi spinosae
- folium ziziphi
- flavone extract
- preparation
- extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930003944 flavone Natural products 0.000 title claims abstract description 60
- 235000011949 flavones Nutrition 0.000 title claims abstract description 60
- 239000000284 extract Substances 0.000 title claims abstract description 58
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 title claims abstract description 53
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 title claims abstract description 53
- 150000002212 flavone derivatives Chemical class 0.000 title claims abstract description 48
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 238000000605 extraction Methods 0.000 title claims abstract description 16
- 240000008866 Ziziphus nummularia Species 0.000 title abstract description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 67
- 239000011347 resin Substances 0.000 claims abstract description 34
- 229920005989 resin Polymers 0.000 claims abstract description 34
- 238000000034 method Methods 0.000 claims abstract description 23
- 238000001179 sorption measurement Methods 0.000 claims abstract description 17
- 230000003064 anti-oxidating effect Effects 0.000 claims abstract description 10
- 238000010992 reflux Methods 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000003814 drug Substances 0.000 claims abstract description 7
- 238000010438 heat treatment Methods 0.000 claims abstract description 7
- 239000007788 liquid Substances 0.000 claims abstract description 6
- 239000012141 concentrate Substances 0.000 claims abstract description 5
- 235000013402 health food Nutrition 0.000 claims abstract description 3
- 230000001476 alcoholic effect Effects 0.000 claims description 12
- 238000010828 elution Methods 0.000 claims description 9
- 239000012535 impurity Substances 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 7
- 239000003480 eluent Substances 0.000 claims description 6
- 238000005507 spraying Methods 0.000 claims description 6
- 238000010521 absorption reaction Methods 0.000 claims description 3
- 239000004793 Polystyrene Substances 0.000 claims description 2
- 238000007654 immersion Methods 0.000 claims description 2
- 229920002223 polystyrene Polymers 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 19
- 238000004587 chromatography analysis Methods 0.000 abstract description 5
- 238000005516 engineering process Methods 0.000 abstract description 5
- 238000001914 filtration Methods 0.000 abstract description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract description 3
- 235000013305 food Nutrition 0.000 abstract description 3
- 229940079593 drug Drugs 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 33
- 229930003935 flavonoid Natural products 0.000 description 12
- 150000002215 flavonoids Chemical class 0.000 description 12
- 235000017173 flavonoids Nutrition 0.000 description 12
- KJCVRFUGPWSIIH-UHFFFAOYSA-N 1-naphthol Chemical compound C1=CC=C2C(O)=CC=CC2=C1 KJCVRFUGPWSIIH-UHFFFAOYSA-N 0.000 description 10
- 230000003078 antioxidant effect Effects 0.000 description 9
- 239000000523 sample Substances 0.000 description 8
- 238000006243 chemical reaction Methods 0.000 description 7
- 238000003795 desorption Methods 0.000 description 7
- 150000002213 flavones Chemical class 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 6
- 230000008030 elimination Effects 0.000 description 6
- 238000003379 elimination reaction Methods 0.000 description 6
- -1 flavone compound Chemical class 0.000 description 5
- 230000036541 health Effects 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 4
- 235000013361 beverage Nutrition 0.000 description 4
- 239000002775 capsule Substances 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 230000002000 scavenging effect Effects 0.000 description 4
- 244000269722 Thea sinensis Species 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 150000001875 compounds Chemical group 0.000 description 3
- 238000002481 ethanol extraction Methods 0.000 description 3
- 230000007760 free radical scavenging Effects 0.000 description 3
- 239000006187 pill Substances 0.000 description 3
- 229920006395 saturated elastomer Polymers 0.000 description 3
- 239000007901 soft capsule Substances 0.000 description 3
- 230000003068 static effect Effects 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 2
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 239000007919 dispersible tablet Substances 0.000 description 2
- 235000013376 functional food Nutrition 0.000 description 2
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 2
- 239000011259 mixed solution Substances 0.000 description 2
- WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 description 2
- 235000005875 quercetin Nutrition 0.000 description 2
- 229960001285 quercetin Drugs 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 238000007670 refining Methods 0.000 description 2
- 239000012488 sample solution Substances 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 238000002798 spectrophotometry method Methods 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- BHQCQFFYRZLCQQ-UHFFFAOYSA-N (3alpha,5alpha,7alpha,12alpha)-3,7,12-trihydroxy-cholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 BHQCQFFYRZLCQQ-UHFFFAOYSA-N 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 239000004380 Cholic acid Substances 0.000 description 1
- WHGYBXFWUBPSRW-UHFFFAOYSA-N Cycloheptaamylose Natural products O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO WHGYBXFWUBPSRW-UHFFFAOYSA-N 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 208000007443 Neurasthenia Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 241000219100 Rhamnaceae Species 0.000 description 1
- ZONYXWQDUYMKFB-UHFFFAOYSA-N SJ000286395 Natural products O1C2=CC=CC=C2C(=O)CC1C1=CC=CC=C1 ZONYXWQDUYMKFB-UHFFFAOYSA-N 0.000 description 1
- 241000612118 Samolus valerandi Species 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000019416 cholic acid Nutrition 0.000 description 1
- BHQCQFFYRZLCQQ-OELDTZBJSA-N cholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 BHQCQFFYRZLCQQ-OELDTZBJSA-N 0.000 description 1
- 229960002471 cholic acid Drugs 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000008298 dragée Substances 0.000 description 1
- 239000006196 drop Substances 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000007941 film coated tablet Substances 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 229930003949 flavanone Natural products 0.000 description 1
- 150000002207 flavanone derivatives Chemical class 0.000 description 1
- 235000011981 flavanones Nutrition 0.000 description 1
- HVQAJTFOCKOKIN-UHFFFAOYSA-N flavonol Natural products O1C2=CC=CC=C2C(=O)C(O)=C1C1=CC=CC=C1 HVQAJTFOCKOKIN-UHFFFAOYSA-N 0.000 description 1
- 150000007946 flavonol Chemical class 0.000 description 1
- 235000011957 flavonols Nutrition 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- GOMNOOKGLZYEJT-UHFFFAOYSA-N isoflavone Chemical compound C=1OC2=CC=CC=C2C(=O)C=1C1=CC=CC=C1 GOMNOOKGLZYEJT-UHFFFAOYSA-N 0.000 description 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
- 235000008696 isoflavones Nutrition 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229940093429 polyethylene glycol 6000 Drugs 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 229940079877 pyrogallol Drugs 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000007940 sugar coated tablet Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 238000002137 ultrasound extraction Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510747487.4A CN105232669B (zh) | 2015-11-05 | 2015-11-05 | 一种酸枣叶黄酮提取物及其制备方法和应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510747487.4A CN105232669B (zh) | 2015-11-05 | 2015-11-05 | 一种酸枣叶黄酮提取物及其制备方法和应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105232669A true CN105232669A (zh) | 2016-01-13 |
CN105232669B CN105232669B (zh) | 2019-05-17 |
Family
ID=55030667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510747487.4A Active CN105232669B (zh) | 2015-11-05 | 2015-11-05 | 一种酸枣叶黄酮提取物及其制备方法和应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105232669B (zh) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109288902A (zh) * | 2018-10-17 | 2019-02-01 | 山西大学 | 一种具有强抗氧化活性的酸枣叶总黄酮发酵产物的制备方法及其应用 |
CN110063993A (zh) * | 2019-04-16 | 2019-07-30 | 山西大学 | 一种酸枣叶总黄酮的用途 |
CN110229205A (zh) * | 2019-07-09 | 2019-09-13 | 山西大学 | 酸枣仁单体成分斯皮诺素钠的制备方法和应用 |
CN111450148A (zh) * | 2020-06-02 | 2020-07-28 | 中国科学院长春应用化学研究所 | 车前子活性部位及其制备方法 |
CN115844779A (zh) * | 2022-11-30 | 2023-03-28 | 中国药科大学 | 一种柑果肉中总黄酮和果酸部位及其制备方法、应用 |
CN115957250A (zh) * | 2022-10-21 | 2023-04-14 | 青海民族大学 | 大籽獐牙菜总黄酮的提取及其在清除氧自由基中的应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101926452A (zh) * | 2009-12-25 | 2010-12-29 | 河北农业大学 | 酸枣叶总黄酮浸膏及其制备方法 |
-
2015
- 2015-11-05 CN CN201510747487.4A patent/CN105232669B/zh active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101926452A (zh) * | 2009-12-25 | 2010-12-29 | 河北农业大学 | 酸枣叶总黄酮浸膏及其制备方法 |
Non-Patent Citations (2)
Title |
---|
李全国: "乐陵枣叶总黄酮的提取、分离纯化、鉴定及其抗氧化活性研究", 《中国优秀硕士学位论文全文数据库,工程科技Ⅰ辑》 * |
白莉等: "山西不同产地野生酸枣叶总黄酮的含量测定", 《山西中医学院学报》 * |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109288902A (zh) * | 2018-10-17 | 2019-02-01 | 山西大学 | 一种具有强抗氧化活性的酸枣叶总黄酮发酵产物的制备方法及其应用 |
CN109288902B (zh) * | 2018-10-17 | 2021-07-27 | 山西大学 | 一种具有强抗氧化活性的酸枣叶总黄酮发酵产物的制备方法及其应用 |
CN110063993A (zh) * | 2019-04-16 | 2019-07-30 | 山西大学 | 一种酸枣叶总黄酮的用途 |
CN110229205A (zh) * | 2019-07-09 | 2019-09-13 | 山西大学 | 酸枣仁单体成分斯皮诺素钠的制备方法和应用 |
CN111450148A (zh) * | 2020-06-02 | 2020-07-28 | 中国科学院长春应用化学研究所 | 车前子活性部位及其制备方法 |
CN115957250A (zh) * | 2022-10-21 | 2023-04-14 | 青海民族大学 | 大籽獐牙菜总黄酮的提取及其在清除氧自由基中的应用 |
CN115844779A (zh) * | 2022-11-30 | 2023-03-28 | 中国药科大学 | 一种柑果肉中总黄酮和果酸部位及其制备方法、应用 |
CN115844779B (zh) * | 2022-11-30 | 2024-05-28 | 中国药科大学 | 一种柑果肉中总黄酮和果酸部位及其制备方法、应用 |
Also Published As
Publication number | Publication date |
---|---|
CN105232669B (zh) | 2019-05-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105232669A (zh) | 一种酸枣叶黄酮提取物及其制备方法和应用 | |
CN105998109B (zh) | 一种芒果核多酚提取物及其制备方法 | |
CN104710391B (zh) | 利用花生壳提取木犀草素和β-谷甾醇的方法 | |
CN102302592B (zh) | 胡柚皮黄酮的制备工艺及其用途 | |
CN102920830A (zh) | 一种高效提取龙眼核中多酚的方法 | |
CN102432582A (zh) | 一种原花青素的制备方法 | |
CN101497594B (zh) | 一种从木豆根茎中提取、分离和纯化染料木素的方法 | |
CN101774955A (zh) | 一种由万寿菊干花颗粒制备高含量反式叶黄素晶体的方法 | |
CN105132172B (zh) | 一种从鸢尾根中制备烟草用鸢尾根黄酮类物质的方法 | |
CN102617673B (zh) | 一种从胡柚白皮层分离纯化柚皮苷和新橙皮苷的方法 | |
CN105267275A (zh) | 一种菊花中黄酮的提取方法 | |
CN101392000A (zh) | 银杏内酯a、b、c、j和白果内酯单体的高效分离纯化方法 | |
CN102659864B (zh) | 一种抗过敏天然产物thbp的制备方法 | |
CN104926767A (zh) | 一种采用大孔吸附树脂纯化制备柑橘黄酮的方法 | |
CN102078341A (zh) | 高纯度银杏黄酮及组合物 | |
CN102302539B (zh) | 一种红车轴草异黄酮的生产方法 | |
CN104000935B (zh) | 一种从马铃薯皮渣中提取抗氧化酚酸的方法 | |
CN106511406B (zh) | 一种银杏叶提取物的制备方法 | |
CN106138130B (zh) | 一种芒果核黄酮提取物及其制备方法 | |
CN101255183A (zh) | 从葫芦巴中提取原薯蓣皂甙的方法 | |
CN107903293A (zh) | 一种金花茶皂苷提取物的萃取工艺 | |
CN111595972A (zh) | 一种多穗柯总黄酮提取物的制备方法及质量检测方法 | |
CN105503981B (zh) | 从紫甘蓝中提取紫甘蓝花青素的方法 | |
CN105294793B (zh) | 景天三七中柚皮苷的分离方法 | |
CN108743632B (zh) | 一种超声波辅助去除白果中银杏酸的方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CP01 | Change in the name or title of a patent holder | ||
CP01 | Change in the name or title of a patent holder |
Address after: 030006 Taiyuan, Xiaodian District, Shanxi City Road, No. 92 Co-patentee after: SHANXI University OF CHINESE MEDICINE Patentee after: Shanxi University Address before: 030006 Taiyuan, Xiaodian District, Shanxi City Road, No. 92 Co-patentee before: SHANXI University OF TRADITIONAL CHINESE MEDICINE Patentee before: Shanxi University |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20200818 Address after: Room 301, building 7, 503 Xingguo Road, Yuhang Economic and Technological Development Zone, Hangzhou City, Zhejiang Province Patentee after: Hangzhou LvXiang Biotechnology Co.,Ltd. Address before: 030006 Taiyuan, Xiaodian District, Shanxi City Road, No. 92 Co-patentee before: SHANXI University OF CHINESE MEDICINE Patentee before: Shanxi University |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20230831 Address after: 334000 Floor 2, Entrepreneurship Base, Fenglingtou Town, Guangxin District, Shangrao City, Jiangxi Province Patentee after: Jiangxi Lvtian Food Co.,Ltd. Address before: 311100 Room 301, building 7, 503 Xingguo Road, Yuhang Economic and Technological Development Zone, Hangzhou City, Zhejiang Province Patentee before: Hangzhou LvXiang Biotechnology Co.,Ltd. |