CN105218554B - 4‑氯吡咯并[2,3‑d]嘧啶的合成工艺 - Google Patents
4‑氯吡咯并[2,3‑d]嘧啶的合成工艺 Download PDFInfo
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- CN105218554B CN105218554B CN201510741146.6A CN201510741146A CN105218554B CN 105218554 B CN105218554 B CN 105218554B CN 201510741146 A CN201510741146 A CN 201510741146A CN 105218554 B CN105218554 B CN 105218554B
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- amino
- pyrimidine
- water
- hydroxy pyrimidines
- synthesis technique
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Catalysts (AREA)
Abstract
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Claims (6)
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CN201510741146.6A CN105218554B (zh) | 2015-11-04 | 2015-11-04 | 4‑氯吡咯并[2,3‑d]嘧啶的合成工艺 |
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CN201510741146.6A CN105218554B (zh) | 2015-11-04 | 2015-11-04 | 4‑氯吡咯并[2,3‑d]嘧啶的合成工艺 |
Publications (2)
Publication Number | Publication Date |
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CN105218554A CN105218554A (zh) | 2016-01-06 |
CN105218554B true CN105218554B (zh) | 2017-12-15 |
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CN201510741146.6A Active CN105218554B (zh) | 2015-11-04 | 2015-11-04 | 4‑氯吡咯并[2,3‑d]嘧啶的合成工艺 |
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CN (1) | CN105218554B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112645956A (zh) * | 2020-12-29 | 2021-04-13 | 天津全和诚科技有限责任公司 | 一种胸苷磷酸化酶抑制剂的前药中间体的制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007116412A1 (en) * | 2006-04-11 | 2007-10-18 | Hadasit Medical Research Services & Development Limited | Substituted pyrimidines, process for their production and their use as effective absorbents of uv irradiation |
CN101830904A (zh) * | 2010-05-18 | 2010-09-15 | 兰州联云志精细化工有限公司 | 一种4-氯吡咯并嘧啶的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104447758B (zh) * | 2014-11-19 | 2017-04-05 | 上海泰坦科技股份有限公司 | 吡唑并[3,4‑d]嘧啶类化合物的合成工艺 |
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2015
- 2015-11-04 CN CN201510741146.6A patent/CN105218554B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007116412A1 (en) * | 2006-04-11 | 2007-10-18 | Hadasit Medical Research Services & Development Limited | Substituted pyrimidines, process for their production and their use as effective absorbents of uv irradiation |
CN101830904A (zh) * | 2010-05-18 | 2010-09-15 | 兰州联云志精细化工有限公司 | 一种4-氯吡咯并嘧啶的制备方法 |
Non-Patent Citations (1)
Title |
---|
Titanium dioxide supported on MWCNTs as an eco-friendly catalyst in the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones accelerated under microwave irradiation;Javad Safari et al.;《New J. Chem.》;20141231;第38卷;第3514-3521页 * |
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Publication number | Publication date |
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CN105218554A (zh) | 2016-01-06 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Synthesis of 4-chloropyrrolo [2,3-d] pyrimidine Effective date of registration: 20220615 Granted publication date: 20171215 Pledgee: The Bank of Shanghai branch Caohejing Limited by Share Ltd. Pledgor: SHANGHAI TITAN TECHNOLOGY Co.,Ltd. Registration number: Y2022310000059 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
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Date of cancellation: 20230802 Granted publication date: 20171215 Pledgee: The Bank of Shanghai branch Caohejing Limited by Share Ltd. Pledgor: SHANGHAI TITAN TECHNOLOGY Co.,Ltd. Registration number: Y2022310000059 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Synthesis process of 4-chloropyrrolo [2,3-d] pyrimidine Effective date of registration: 20230829 Granted publication date: 20171215 Pledgee: The Bank of Shanghai branch Caohejing Limited by Share Ltd. Pledgor: SHANGHAI TITAN TECHNOLOGY Co.,Ltd. Registration number: Y2023310000500 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |