CN105168522A - Medicament for treating abdominal distension and preparation method thereof - Google Patents
Medicament for treating abdominal distension and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicament for treating abdominal distension and a preparation method thereof. The medicament is prepared from the following components in parts by weight: 9 to 15 parts of evodia, 7 to 16 parts of phymatopsis griffithiana, 6 to 12 parts of burmann cinnamon bark, 10 to 15 parts of minced orchid root, 8 to 14 parts of cynanchum glaucescens, 11 to 15 parts of beet root, 9 to 14 parts of coriander seed, 7 to 15 parts of phoebe sheareri root, 8 to 12 parts of asiatic striga, 10 to 16 parts of clove, 8 to 17 parts of thunbergia fragrans, 6 to 14 parts of tetrapanax papyriferus, and 9 to 13 parts of valerian root. The medicament is safe, does not have any side effect or adverse reaction, has a prominent curative effect, and can treat both the root and symptoms of abdominal distension, and the relapse is difficult.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of medicament and the method for making of curing abdominal distention.
Background technology
Abdominal distention, namely abdominal part swells or distension discomfort.Can be a kind of subjective sensation, feel a part for abdominal part or full abdominal part distension, usually normal with relevant symptom, as vomiting, diarrhoea, belch etc.; Also can be a kind of inspection finding objectively, find an abdominal part part or full abdominal tympanites.Abdominal distention is a kind of common gastrointestinal symptom, causes the reason of abdominal distention to be mainly seen in ascites, belly cavity tumor etc. caused by gastrointestinal tract flatulence, a variety of causes.Flatulence all has abdominal tympanites in general, the bulge being confined to epigastrium is more common in caused by stomach or transverse colon pneumatosis, little intestinal gas abdominal tympanites can be confined to midriff, also can be full abdominal tympanites, aerocoly abdominal tympanites can be confined to hypogastric region or left lower abdomen, during pyloric obstruction, epigastrium can have gastric pattern and peristalsis, visible visible peristalsis visible intestinal peristalsis and peristaltic wave during intestinal obstruction, bowel sound hyperaction or weaken, peritonitis patient can have tenderness and muscle tonus." General Treatise on the Cause and Symptoms of Diseases abdominal distention time ": " abdominal distention person, by the outer void of yang-energy, cloudy gas inner product therefore also.Yang-energy is outer empty by air-cooled pathogen, and air-cooled, cloudy gas also.Cold amassing is not fallen apart between mansion is dirty, stops up mutually with temper, and void is then swollen, therefore abdominal distention and feeble QI is breathed heavily." (1) spleen injury.Due to children's's excess in feeding, hungry full immoderate, or malnutrition, all can impairing the spleen and stomach, make dysfunction of the spleen in transportation, lifting is forfeited one's integrity, and the stagnation of QI can not normally be run and cause distension and fullness in the abdomen.(2) emotional factors.Have wilfulness, being unable to satisfy the wants owing to pampering children's, feelings will is unhappy, and irritability is pent-up thus, disorder of movement of QI more, can cause abdominal distention out of breath.(3) damp-heat accumulation.The damp and hot heresy of summer and autumn diseases caused by exogenous pathogenic factor, must not Xuanhua, stops up stagnant in middle Jiao, the strongly fragrant resistance of mechanism of qi, taste elevating function is lacked of proper care, so that abdominal distention uncomfortable in chest.(4) invasion by pathogenic cold.Children's's polyphagia cold drink or clothing are excessively thin, experience cold-evil, and pathogenic cold attacking directly the spleen and stomach makes hypoactivity of spleen-YANG, and can not wet by Wen Huashui, essence of water and grain material can not defeated cloth, stop up to amass to form abdominal distention in middle Jiao.In addition, liver hinders then coagulation of QI-blood, and venation is blocked, and formation is gathered.Disease is impairment of the kidney for a long time, insufficiency of kidney-YANG, is difficult replenishing vital QI with drugs of warm nature spleen soil, evaporates water and wets, damage of kidney-YIN, and liver is lost and nourishes, and all can cause abdominal distention.
Treatment: one, Syndrome Differentiation of Chinese Medicine is controlled: " Zhang Shi cure inflation full ": " all cards of abdominal distention, though it is many to belong to cold person, belong to hot person few, right generation is controlled swollen, likes the medicine of the gas that to fall apart by pungent temperature.Have the deficiency of vital energy not wrap up in blood, blood is loose do swollen, must its people stool tight, or time knot time half congealed, half congealed, slightly subtract, knot then gradually adds; Urine is sharp clearly, and very then muddy in vain as water from washing rice, its moderate pulse is large and stagnant, and very, the medicine of careful unavailable pungent temperature consumption gas, should four gentleman go the Rhizoma Atractylodis Macrocephalae to add the Radix Aucklandiae, Rhizoma Alismatis, Radix Angelicae Sinensis, Radix Paeoniae with the blood in its gas solid to QI KOU benefit.Have blood deficiency can not astringing QI, gas is loose do swollen, must its people's dysphoria with smothery sensation just dry, yellow urine number, its floating and rapid pulse and string, more so, the medicine that careful unavailable bitter cold injures one's stomach, should SIWU TANG go Radix Rehmanniae to add the Radix Astragali, Cortex Cinnamomi, Radix Glycyrrhizae, Roast Rhizoma Zingiberis Recens in Renying, with the gas in its blood.Exopathogenic factor six gas becomes swollen, huoxiang zhengqi powder; Endogenous cause of ill seven emotions become swollen, and Lignum Aquilariae Resinatum sending down the abnormal ascending QI falls apart.Be worried excessively, taste of causing injury, trusted subordinate's tympanites, dyspnea with rapid and short breath is unhappy, and borborygmus are made leave with rage, and filter sound, defecation is unfavorable, deficient pulse and puckery, office side seven gas soup.Turbid QI failing to descend, then give birth to (moon is true) swollen, Shengjian Xiexin Tang adds the Radix Aucklandiae, Cortex Magnoliae Officinalis.(" simple and clear doctor draws a bow to the full " the pleasant soup of the opinion Radix Aucklandiae).Taste are not warm, can not digesting food and swollen, cling conditions.Kidney deficiency and coldness, can not biochemical spleen soil and swollen, JISHENG SHENQI WAN." heart spleen is injured for troubled thoughts, abdominal distention has dyspnea with rapid and short breath, vomiting, borborygmus, difficulty in urination and defecation person concurrently.Available Fructus Perillae soup.It also can cause abdominal distention as food stagnation, malnutrition due to parasitic infestation etc.Two, the nonprescription drugs selected: 1, Western medicine nonprescription drugs: simethicone also claims polydimethyl siloxane fluid is antiflatulent.This medicine can reduce surface tension, eliminates the foam in gastrointestinal tract, the gas by foam stores is got rid of, thus alleviates flatulence.Its dosage form is tablet, oral application.Medicinal charcoal also claims active carbon, can adsorb the gas that enteral abnormal fermentation produces, alleviate abdominal distention.Its dosage form is tablet, oral application.Lactasinum also claims biofermin, is enterococcal drying agent of living.This medicine generates lactic acid at intestinal degradation saccharide, and enteral acidity is increased, and suppresses the growth and breeding of enteral putrefaction bacteria, alleviates fermentation and aerogenesis.Its dosage form is tablet, oral application.Oral Bacillus licheniformis viable bacteria granular also claims Bacillus Licheniformis Capsule, adjustable alteration of intestinal flora, maintains ecological balance, eliminates the disease such as dyspepsia, abdominal distention.Its dosage form is capsule, granule, oral application.Domperidone, also known as motilium, Domperidone, can increase gastrointestinal smooth muscular tension and wriggling, and gastric emptying speed is accelerated, digestion and propelling food, promotes that food and intestinal gas are discharged.For dyspepsia, abdominal distention, belch etc.Its dosage form is tablet, oral application.2, Chinese patent medicine nonprescription drugs have aplotaxis carminative pill, XIANGSHA YANGWEI WAN, 'Chenxiang Huaqi sheet, fourth sink diaphragm ball, regulating QI ball, compound recipe Fortunella crassifolia Swingle electuary, Hewei Pinggan Pills, HOUTOU JIANWEI JIAONANG, add taste four and to disappear ball, spleen-strengthening bolus, Jiebai capsule, long-pending art ball, ease pill, Liuwei-Nengxiao capsules, MOLUO DAN etc.Three, self-medication: Western medicine: galactenzyme raw cook, be grown up one time 0.3 gram ~ 0.9 gram, 3 times on the one.Also can take bacillus cicheniformis (Bacillus Licheniformis Capsule), adult, granule, one time 1 bag; Capsule, one time 2,3 times on the one, first dose doubles.Child dose reduces by half.Domperidone (motilium), tablet, be grown up one time 1 (10 milligrams), one day 1 ~ 2 time.Chinese patent medicine: as patient is willing to eat Chinese patent medicine, then according to theory of Chinese medical science, can select by syndrome is dialectical.Abdominal distention caused by dampness hampering qi movement, available aplotaxis carminative pill, oral, one time 6 grams ~ 9 grams, 2 ~ 3 times on the one.Abdominal distention caused by irritability stasis, available ease pill, oral, one time 6 grams ~ 9 grams, 2 times on the one.Abdominal distention caused by the insufficiency of the spleen stagnation of QI, available Aurantii Immaturi and Atractylodis Pill, oral, one time 6 grams, 2 times on the one.Also spleen-strengthening bolus can be taken.
Application publication number CN103041334A(application number 201210560883.2) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of abdominal distention, it is made up of the raw material of Chinese medicine of following weight portion: Rhizoma Pinelliae 5-20 part, Rhizoma Coptidis 5-20 part, Radix Scutellariae 5-20 part, Rhizoma Zingiberis 5-20 part, Radix Codonopsis 10-25 part, Fructus Amomi 5-20 part, Cortex Magnoliae Officinalis 5-20 part, Endothelium corneum 10-25 part, Fructus Aurantii Immaturus 5-20 part, Rhizoma Atractylodis Macrocephalae (parched) 10-30 part, Fructus Evodiae 3-15 part, Radix Angelicae Dahuricae 10-25 part, Herba Taraxaci 10-30 part, fry BUZI 10-25 part, Os Sepiae 10-40 part.Application publication number CN103721194A(application number 201410005443.X) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of abdominal distention, its raw material of Chinese medicine and weight are: Radix Et Rhizoma Rhei 5-20 part, Cortex Phellodendri 5-25 part, Fructus Aurantii 10-30 part, Radix Curcumae 5-25 part, Semen Ziziphi Spinosae 10-40 part, Pheretima 5-25 part, Semen Raphani 10-30 part, Radix Angelicae Sinensis 5-25 part, Rhizoma Cyperi 5-25 part, Poria cum Radix Pini 10-30 part, Radix Ophiopogonis 5-20 part, Radix Panacis Quinquefolii 5-25 part, Radix Polygalae 5-20 part, Fructus Amomi 5-25 part, Os Draconis 5-25 part, Concha Ostreae 10-30 part, Cornu Bubali 5-25 part, Fructus Gardeniae 5-25 part, Rhizoma Coptidis 5-20 part, Colla Corii Asini 5-20 part, Radix Glycyrrhizae 5-15 part.Application publication number CN103463502A(application number 201310451833.5) Chinese patent literature disclose a kind of medicine for the treatment of abdominal distention, particularly relate to a kind of Chinese medicine preparation for the treatment of abdominal distention, crude drug primarily of following weight portion is made: Radix Bupleuri 7 ~ 13 parts, Fructus Forsythiae 7 ~ 13 parts, Herba Lophatheri 7 ~ 13 parts, Radix Scutellariae 7 ~ 13 parts, Cortex Moutan 7 ~ 13 parts, Herba Artemisiae Scopariae 12 ~ 18 parts, Fructus Arctii (parched) 3 ~ 9 parts, Flos Lonicerae 12 ~ 18 parts.
At present, western medical treatment abdominal distention is based on symptomatic treatment, and there is no the specific drug for abdominal distention, curative effect is not good enough, easily recurs after drug withdrawal, also has side effects to patient body.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of medicament and the method for making of curing abdominal distention.Safety of the present invention, has no side effect and untoward reaction, evident in efficacy, and treating both the principal and secondary aspects of a disease, not easily recurs after healing.
Technical scheme of the present invention is:
Cure the medicament of abdominal distention, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Evodiae 9-15, Phymatopsis griffithiana (Hook.) J. Sm. 7-16, Cortex Cinnamomi Burmannii 6-12, broken orchid root 10-15, Rhizoma Cynanchi Stauntonii 8-14 Radix Betae 11-15, Fructus Coriandri 9-14, Radix phoebes sheareri 7-15, Herba Strigae Asiaticae 8-12, Flos Caryophylli 10-16, Thunbergia fragrans Roxb. 8-17, Radix tetrapanacis Koch 6-14, Rhizoma et radix valerianae 9-13.
Cure the medicament of abdominal distention, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Fructus Evodiae 10-13, Phymatopsis griffithiana (Hook.) J. Sm. 11-14, Cortex Cinnamomi Burmannii 8-11, broken orchid root 12-14, Rhizoma Cynanchi Stauntonii 9-12 ， Radix Betae 12-14, Fructus Coriandri 10-13, Radix phoebes sheareri 10-13, Herba Strigae Asiaticae 9-11, Flos Caryophylli 12-15, Thunbergia fragrans Roxb. 10-15, Radix tetrapanacis Koch 8-12, Rhizoma et radix valerianae 10-12.
Cure the medicament of abdominal distention, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Fructus Evodiae 12, Phymatopsis griffithiana (Hook.) J. Sm. 13, Cortex Cinnamomi Burmannii 10, broken orchid root 13, Rhizoma Cynanchi Stauntonii 11 ， Radix Betae 13, Fructus Coriandri 12, Radix phoebes sheareri 11, Herba Strigae Asiaticae 10, Flos Caryophylli 14, Thunbergia fragrans Roxb. 12, Radix tetrapanacis Koch 11, Rhizoma et radix valerianae 11.
Present invention also offers the preparation method medicament of aforementioned treatment abdominal distention being made pharmaceutically acceptable powder, pill, tablet and granule.
The preparation method of described powder is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 12-18 minute (preferred slow fire stir-fries 15 minutes), takes out, smashs to pieces after cooling, and adds Fructus Coriandri weight 8-12 water (preferably adding the water of Fructus Coriandri weight 11 times) doubly, decocts 30 minutes, leach medicinal liquid;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 150-180 mesh sieve (preferred mistake 170 mesh sieve);
(3) all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli are cleaned, put into pot, add 11 taste crude drug 4.8-6 water (preferably adding the water of 11 taste crude drug 5.2 times) doubly, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 20-30 minute (fire of preferably larding speech with literary allusions boils 26 minutes), leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste (preferably the supernatant being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, put into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 150-180 mesh sieve (preferred mistake 170 mesh sieve);
(5) by step (2) and the mixing of step (4) gained, make popular with pot, after its cooling, encapsulate often to wrap in 4g loading sterile bag, to obtain final product.
The preparation method of described pill is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 12-18 minute (preferred slow fire stir-fries 15 minutes), takes out, smashs to pieces after cooling, and adds Fructus Coriandri weight 8-12 water (preferably adding the water of Fructus Coriandri weight 11 times) doubly, decocts 30 minutes, leach medicinal liquid;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(3) all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli are cleaned, put into pot, add 11 taste crude drug 4.8-6 water (preferably adding the water of 11 taste crude drug 5.2 times) doubly, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 20-30 minute (fire of preferably larding speech with literary allusions boils 26 minutes), leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste (preferably the supernatant being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, put into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(5) by step (2) and the mixing of step (4) gained, with the general ball of rice vinegar, make the pill that particle diameter is 3mm, 40 DEG C of water content being dried to pill, lower than 2%, to obtain final product.
The preparation method of described tablet is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 12-18 minute (preferred slow fire stir-fries 15 minutes), takes out, smashs to pieces after cooling, and adds Fructus Coriandri weight 8-12 water (preferably adding the water of Fructus Coriandri weight 11 times) doubly, decocts 30 minutes, leach medicinal liquid;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(3) all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli are cleaned, put into pot, add 11 taste crude drug 4.8-6 water (preferably adding the water of 11 taste crude drug 5.2 times) doubly, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 20-30 minute (fire of preferably larding speech with literary allusions boils 26 minutes), leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste (preferably the supernatant being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, put into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(5) by step (2) and the mixing of step (4) gained, stir, add 10% starch slurry, make soft material, with 14 mesh sieve wet granulars, 45 DEG C are dried to moisture less than 2%, are pressed into the tablet of the heavy 0.4g of every sheet, obtain final product.
The preparation method of described granule is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 12-18 minute (preferred slow fire stir-fries 15 minutes), takes out, smashs to pieces after cooling, and adds Fructus Coriandri weight 8-12 water (preferably adding the water of Fructus Coriandri weight 11 times) doubly, decocts 30 minutes, leach medicinal liquid;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(3) all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli are cleaned, put into pot, add 11 taste crude drug 4.8-6 water (preferably adding the water of 11 taste crude drug 5.2 times) doubly, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 20-30 minute (fire of preferably larding speech with literary allusions boils 26 minutes), leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste (preferably the supernatant being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, put into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(5) by step (2) and the mixing of step (4) gained, stir, add 10% starch slurry, make soft material, with 14 mesh sieve wet granulars, 45 DEG C are dried to moisture less than 2%, and dry granule is again through 14 mesh sieve granulate, and subpackage, sealing, packaging, to obtain final product.
The drug prescription science for the treatment of abdominal distention provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:
1, safety, has no side effect and untoward reaction;
2, there is effect of dispersing cold for relieving pain, clearing away heat-damp and promoting diuresis, eliminating the pathogens from the lung sending down the abnormal ascending QI, stomach invigorating removing food stagnancy, warming middle-JIAO to send down the adverse QI, can autoimmune function be strengthened, finally reach the object of healing;
3, medicine source is extensive, and cheap;
4, evident in efficacy, treating both the principal and secondary aspects of a disease, not easily recurs after healing.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1cure the medicament of abdominal distention, the primary raw material medicine getting following weight parts is prepared from (every part is 560g): Fructus Evodiae 9 parts, Phymatopsis griffithiana (Hook.) J. Sm. 7 parts, Cortex Cinnamomi Burmannii 6 parts, broken orchid root 10 parts, Rhizoma Cynanchi Stauntonii 8 parts of Radix Betae 11 parts, Fructus Coriandri 9 parts, Radix phoebes sheareri 7 parts, Herba Strigae Asiaticae 8 parts, Flos Caryophylli 10 parts, Thunbergia fragrans Roxb. 8 parts, Radix tetrapanacis Koch 6 parts, Rhizoma et radix valerianae 9 parts.
The preparation method of the medicament powder of above-mentioned treatment abdominal distention is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 12 minutes, takes out, smashs to pieces, add the water of Fructus Coriandri weight 8 times, decoct 30 minutes, leach medicinal liquid after cooling;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 150 mesh sieves;
(3) cleaned by all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli, put into pot, add the water of 11 taste crude drug 4.8 times, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 20 minutes, leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste that relative density is 1.32, puts into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 150 mesh sieves;
(5) by step (2) and the mixing of step (4) gained, make popular with pot, after its cooling, encapsulate often to wrap in 4g loading sterile bag, to obtain final product.
The instructions of taking that gained of the present invention cures the medicament powder of abdominal distention is: oral, one day twice, each 4g, boiled water was taken after mixing it with water.
embodiment 2cure the medicament of abdominal distention, the primary raw material medicine getting following weight parts is prepared from (every part is 560g): Fructus Evodiae 15 parts, Phymatopsis griffithiana (Hook.) J. Sm. 16 parts, Cortex Cinnamomi Burmannii 12 parts, broken orchid root 15 parts, Rhizoma Cynanchi Stauntonii 14 parts of Radix Betae 15 parts, Fructus Coriandri 14 parts, Radix phoebes sheareri 15 parts, Herba Strigae Asiaticae 12 parts, Flos Caryophylli 16 parts, Thunbergia fragrans Roxb. 17 parts, Radix tetrapanacis Koch 14 parts, Rhizoma et radix valerianae 13 parts.
The preparation method of the medicament pill of above-mentioned treatment abdominal distention is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 15 minutes, takes out, smashs to pieces, add the water of Fructus Coriandri weight 11 times, decoct 30 minutes, leach medicinal liquid after cooling;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 130 mesh sieves;
(3) cleaned by all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli, put into pot, add the water of 11 taste crude drug 5.2 times, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 26 minutes, leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste that relative density is 1.34, puts into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 130 mesh sieves;
(5) by step (2) and the mixing of step (4) gained, with the general ball of rice vinegar, make the pill that particle diameter is 3mm, 40 DEG C of water content being dried to pill, lower than 2%, to obtain final product.
model case one:wu XX, female, 43 years old.Abdominal distention more than 1 year.Before 1 year, there is abdominal distention in patient, and borborygmus increases the weight of after meal.Once nearby clinic, gives Drug therapy, does not feel any better.Then to our hospital.Examine and see that gastral cavity abdomen is swollen, borborygmus, postprandial diarrhea, greasy, the raw and cold postemphasis of edible oil, abdomen has bearing down, and defecation seasonal epidemic pathogens goes out, and abdominal distention is alleviated after an action of the bowels, and companion's deficiency of QI with disinclination to talk, limbs are sleepy, pale tongue with white fur, thready and weak pulse.Take the medicament pill that the present embodiment gained cures abdominal distention, oral, three times on the one, each 2 balls, warm water takes.Take 5 days, abdominal distention obviously alleviates.Continue to take 1 week, all transference cures, cure.Follow up a case by regular visits to and do not recur.
embodiment 3cure the medicament of abdominal distention, the primary raw material medicine getting following weight parts is prepared from (every part is 560g): Fructus Evodiae 10 parts, Phymatopsis griffithiana (Hook.) J. Sm. 11 parts, Cortex Cinnamomi Burmannii 8 parts, broken orchid root 12 parts, Rhizoma Cynanchi Stauntonii 9 parts of Radix Betae 12 parts, Fructus Coriandri 10 parts, Radix phoebes sheareri 10 parts, Herba Strigae Asiaticae 9 parts, Flos Caryophylli 12 parts, Thunbergia fragrans Roxb. 10 parts, Radix tetrapanacis Koch 8 parts, Rhizoma et radix valerianae 10 parts.
The preparation method of the medicament tablet of above-mentioned treatment abdominal distention is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 15 minutes, takes out, smashs to pieces, add the water of Fructus Coriandri weight 11 times, decoct 30 minutes, leach medicinal liquid after cooling;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 130 mesh sieves;
(3) cleaned by all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli, put into pot, add the water of 11 taste crude drug 5.2 times, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 26 minutes, leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste that relative density is 1.34, puts into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 130 mesh sieves;
(5) by step (2) and the mixing of step (4) gained, stir, add 10% starch slurry, make soft material, with 14 mesh sieve wet granulars, 45 DEG C are dried to moisture less than 2%, are pressed into the tablet of the heavy 0.4g of every sheet, obtain final product.
model case two:wei, XX, male, 32 years old.Before 3 years, Mr. Wei starts to occur abdominal distention, and with the symptom such as nausea and vomiting, stomachache.Over 3 years, patient goes to a doctor everywhere, takes various medicine, and the state of an illness again and again, fails to cure.Then to our hospital.Examine and see abdominal part distension, nausea and vomiting, stomachache, rare water sample of defecating, smelly dirty, thick fur is greasy, rolling pulse.Take the medicament tablet that the present embodiment gained cures abdominal distention, oral, three times on the one, each two panels, warm water takes.Take 1 week, the symptom such as abdominal distention, stomachache obviously alleviates.Continue to take 1 week, all transference cures, cure.Follow up a case by regular visits to and do not recur.
embodiment 4cure the medicament of abdominal distention, the primary raw material medicine getting following weight parts is prepared from (every part is 560g): Fructus Evodiae 13 parts, Phymatopsis griffithiana (Hook.) J. Sm. 14 parts, Cortex Cinnamomi Burmannii 11 parts, broken orchid root 14 parts, Rhizoma Cynanchi Stauntonii 12 parts of Radix Betae 14 parts, Fructus Coriandri 13 parts, Radix phoebes sheareri 13 parts, Herba Strigae Asiaticae 11 parts, Flos Caryophylli 15 parts, Thunbergia fragrans Roxb. 15 parts, Radix tetrapanacis Koch 12 parts, Rhizoma et radix valerianae 12 parts.
The preparation method of the pharmacy particle agent of above-mentioned treatment abdominal distention is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 15 minutes, takes out, smashs to pieces, add the water of Fructus Coriandri weight 11 times, decoct 30 minutes, leach medicinal liquid after cooling;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 130 mesh sieves;
(3) cleaned by all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli, put into pot, add the water of 11 taste crude drug 5.2 times, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 26 minutes, leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste that relative density is 1.34, puts into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 130 mesh sieves;
(5) by step (2) and the mixing of step (4) gained, stir, add 10% starch slurry, make soft material, with 14 mesh sieve wet granulars, 45 DEG C are dried to moisture less than 2%, and dry granule is again through 14 mesh sieve granulate, and subpackage, sealing, packaging, to obtain final product.
model case three:king XX, man, 29 years old.Before half a year, abdominal postoperative, the symptoms such as abdominal distention appears in patient, inappetence.Once treated at local hospital, and failed to cure.Then to our hospital.Examine and see patient's tripe distention and fullness in the abdomen, inappetence, companion's belch is felt sick, and stool is few, white and greasy fur, thready and moderate pulse.Take the pharmacy particle agent that the present embodiment gained cures abdominal distention, oral, three times on the one, each 8g, boiled water is taken after mixing it with water.Take 5 days, symptom is eased.Continue to take 5 days, all transference cures, cure.Follow up a case by regular visits to and do not recur.
embodiment 5cure the medicament of abdominal distention, the primary raw material medicine getting following weight parts is prepared from (every part is 560g): Fructus Evodiae 12 parts, Phymatopsis griffithiana (Hook.) J. Sm. 13 parts, Cortex Cinnamomi Burmannii 10 parts, broken orchid root 13 parts, Rhizoma Cynanchi Stauntonii 11 parts of Radix Betae 13 parts, Fructus Coriandri 12 parts, Radix phoebes sheareri 11 parts, Herba Strigae Asiaticae 10 parts, Flos Caryophylli 14 parts, Thunbergia fragrans Roxb. 12 parts, Radix tetrapanacis Koch 11 parts, Rhizoma et radix valerianae 11 parts.
The preparation method of the medicament powder of above-mentioned treatment abdominal distention is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 15 minutes, takes out, smashs to pieces, add the water of Fructus Coriandri weight 11 times, decoct 30 minutes, leach medicinal liquid after cooling;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 170 mesh sieves;
(3) cleaned by all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli, put into pot, add the water of 11 taste crude drug 5.2 times, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 26 minutes, leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste that relative density is 1.34, puts into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 170 mesh sieves;
(5) by step (2) and the mixing of step (4) gained, make popular with pot, after its cooling, encapsulate often to wrap in 4g loading sterile bag, to obtain final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Fructus Evodiae: base is former: be the immature fruit of rutaceae Fructus Evodiae.The property of medicine: pungent, bitter, heat, mild toxicity.Return liver, stomach, spleen, large intestine, kidney channel.Function cures mainly: dispersing cold for relieving pain, the soothing the liver therapeutic method to keep the adverse QI flowing downwards, warming middle-JIAO dampness.Main coldness and pain in the epigastrium, headache due to JUE YIN disorder, colic, beriberi swells and ache, and vomiting acid regurgitation, cold-damp is had loose bowels.
Phymatopsis griffithiana (Hook.) J. Sm.: base is former: be the herb of Plants of Polypodiaceae Phymatopsis integrifolia Ching.The property of medicine: bitter; Cold; Nontoxic.GUIXIN, large intestine, small intestinal, spleen channel.Function cures mainly: clearing away heat and cooling blood; Removing toxic substances and promoting subsidence of swelling.Main carbuncle and ulcer; Toxic swelling; Scrofula; Malignant boil; Sudden and violent red acute catarrhal conjunctivitis; Cough due to lung-heat; Stranguria; Discharging fresh blood stool.
Cortex Cinnamomi Burmannii: base is former: be the cloudy fragrant bark of canella.The property of medicine: pungent; Micro-sweet; Warm in nature.Return spleen channel.Function cures mainly: warming middle-JIAO to relieve pain; Expelling wind and cold; Removing toxic substances and promoting subsidence of swelling; Hemostasis.Cure mainly cold stomachache; Stomachache is had loose bowels; Inappetence; Anemofrigid-damp arthralgia; Lumbago and skelalgia; Traumatic injury; Wound hemorrhage; Furuncle toxic swelling.
Broken orchid root: base is former: be the root of labiate Rabdosia coesta.The property of medicine: bitter in the mouth; Cool in nature.Function cures mainly: clearing away heat-damp and promoting diuresis; Promoting blood circulation and stopping pain.Main jaundice due to damp-heat; The pain over the hypochondriac region; Traumatic pain.
Rhizoma Cynanchi Stauntonii: base is former: be the root and rhizome of asclepiadaceae plant rhizoma et radix cynanchi stauntoni or leaves of Daphne genkwa Rhizoma Cynanchi Stauntonii.Chemical analysis: containing triterpenoid saponin, extra large opium poppy glycoside unit A, B, extra large Semen Papaveris glycoside A and extra large Semen Papaveris glycoside unit C-Semen Thevetiae monosaccharide glycoside etc.Leaves of Daphne genkwa Rhizoma Cynanchi Stauntonii is containing triterpenoid saponin.The property of medicine: pungent, sweet, tepor.Return lung meridian.Function cures mainly: eliminating the pathogens from the lung sending down the abnormal ascending QI, lower expectorant antitussive.Control excess of the lung dyspnea with fullness of the chest, cough, excessive phlegm, gastralgia.
Radix Betae: base is former: be the root of chenopod Radix Betae platymiscium Chard dish and preserved carrot.The property of medicine: principle of Correct Diet: " sweet, flat, nontoxic." function cures mainly: principle of Correct Diet: " qualcomm meridian, the therapeutic method to keep the adverse QI flowing downwards open chest.”
Fructus Coriandri: base is former: be the fruit of samphire coriander.The property of medicine: acrid in the mouth; Acid; Property is put down.Return lung, stomach, large intestine channel.Function cures mainly: stomach invigorating removing food stagnancy; Regulating QI to relieve pain; Rash is detoxified.Staple food amasss; Inappetence; Chest and diaphragm is full vexed; Abdominal distention; Vomiting and nausea regurgitation; Dysentery; Discharging fresh blood stool; Proctoptosis; Hernia; Measles; Peppery rash is not saturating; Tinea alba; Headache; Toothache; Boil of the external auditory meatus.
Radix phoebes sheareri: base is former: be the root of Lauraceae Phoebe Nees Cortex phoebes sheareri.The property of medicine: pungent, temperature.Function cures mainly: control traumatic injury, hastens parturition.Main traumatic injury; Edema abdominal distention; Anemia of pregnant woman crosses the moon and does not produce.
Herba Strigae Asiaticae: base is former: be the herb of goatweed Herba Lobeliae Chinensis.The property of medicine: sweet in the mouth; Micro-hardship; Cool in nature.Return liver, spleen, stomach warp.Function cures mainly: spleen invigorating removing food stagnancy; Heat clearing away parasite killing.Main child dyspepsia caused by overeating; Infantile malnutrition general edema with yellowish skin; Nyctalopia; Summer fever; Diarrhoea; Hepatitis.
Flos Caryophylli: base is former: be the alabastrum of dicotyledon medicine plant clove of myrtaceae.The property of medicine: acrid in the mouth; Warm in nature.Return spleen, stomach, kidney channel.Function cures mainly: warming middle-JIAO to send down the adverse QI, warming the kidney to activate YANG.Main singultus, coldness and pain in the epigastrium, lack of appetite leaf rushes down, impotence due to deficiency of the kidney, and the acid of waist knee joint is cold, carbuncle of yin nature.
Thunbergia fragrans Roxb.: base is former: be the stem and leaf of acanthaceous plant Thunbergia fragrans Roxb..The property of medicine: acrid in the mouth; Micro-acid; Property is put down.Function cures mainly: invigorating the stomach and promoting digestion; Removing toxic substances and promoting subsidence of swelling.Main dyspepsia; Abdominal distention; Diarrhoea; Carbuncle furuncle.
Radix tetrapanacis Koch: base is former: be the root of Araliaceae rice-paper plant.The property of medicine: lightly seasoned; Micro-hardship; Cold nature.Function cures mainly: clearing away heat and promoting diuresis; Promote qi circulation digestion promoting; To invigorate blood circulation stimulating milk secretion.Main edema; Stranguria; Food stagnation drink is swollen; Mass in the abdomen; Rheumatic arthralgia; Menoxenia; Agalactia.
Rhizoma et radix valerianae: base is former: be root, the rhizome of Valerianaceae plant Rhizoma et radix valerianae, Valeriana amurensis, Valeriana officinalis var. latifolia.The property of medicine: acrid in the mouth; Bitter; Warm in nature.GUIXIN, Liver Channel.Function cures mainly: tranquilizing mind.Main irritability; Palpitation and insomnia; Demented; Hysteria; Rheumatic arthralgia; Dysmenorrhea; Amenorrhea; Traumatic injury.
test example 1gained of the present invention cures the clinical practice of the medicament (embodiment 5) of abdominal distention: in October, 2011 in December ,-2012, screen 276 routine abdominal distention patients in 3 hospitals, wherein male 148 example, women 128 example, age 20-65 year.Be divided into two groups at random, experimental group and matched group (often organizing 138 examples).Between two groups of patients, the aspect such as sex, age, state of an illness compares, and no significant difference (P > 0.05), has comparability.
Therapeutic Method: experimental group uses gained of the present invention to cure the medicament of abdominal distention, and using method is: oral, one day twice, each 4g, and boiled water is taken after mixing it with water, and 7 days is a course for the treatment of.Matched group uses the Drug therapys such as Trimebutine sheet, Dispersible Mosapride citrate tablets, motilium, within 7 days, is a course for the treatment of.Comparitive study is carried out after two groups of patients all treat two courses for the treatment of.
Curative effect situation criterion: cure: clinical symptoms and sign disappear; Take a turn for the better: clinical symptoms and sign partial disappearance or alleviate; Invalid: clinical symptoms and sign are without improvement.
Table 1: gained of the present invention cures the pharmacy effect checking of abdominal distention
Efficacy analysis: after two groups of cases treat two courses for the treatment of, experimental group cures 100 examples, and take a turn for the better 36 examples, invalid 2 examples, total effective rate 98.55%; Matched group cures 46 examples, and take a turn for the better 65 examples, invalid 27 examples, total effective rate 80.43%.The clinical efficacy of experimental group is obviously better than matched group, and significant difference (P < 0.05), has statistical significance.
The present invention is primary raw material medicine with Fructus Evodiae, Phymatopsis griffithiana (Hook.) J. Sm., Cortex Cinnamomi Burmannii and broken orchid root etc., makes the medicament of curing abdominal distention.Fructus Evodiae dispersing cold for relieving pain in side, the soothing the liver therapeutic method to keep the adverse QI flowing downwards, warming middle-JIAO dampness.Phymatopsis griffithiana (Hook.) J. Sm. clearing away heat and cooling blood; Removing toxic substances and promoting subsidence of swelling.Cortex Cinnamomi Burmannii warming middle-JIAO to relieve pain; Expelling wind and cold; Removing toxic substances and promoting subsidence of swelling; Hemostasis.Broken orchid root clearing away heat-damp and promoting diuresis; Promoting blood circulation and stopping pain.Rhizoma Cynanchi Stauntonii eliminating the pathogens from the lung sending down the abnormal ascending QI, lower expectorant antitussive.Radix Betae qualcomm meridian, the therapeutic method to keep the adverse QI flowing downwards, opens chest.Fructus Coriandri stomach invigorating removing food stagnancy; Regulating QI to relieve pain; Rash is detoxified.Cortex phoebes sheareri radical cure traumatic injury, hastens parturition.Herba Strigae Asiaticae spleen invigorating removing food stagnancy; Heat clearing away parasite killing.Flos Caryophylli warming middle-JIAO to send down the adverse QI, warming the kidney to activate YANG.Thunbergia fragrans Roxb. invigorating the stomach and promoting digestion; Removing toxic substances and promoting subsidence of swelling.Radix tetrapanacis Koch clearing away heat and promoting diuresis; Promote qi circulation digestion promoting; To invigorate blood circulation stimulating milk secretion.Rhizoma et radix valerianae tranquilizing mind.All medicines share, and play the effect of dispersing cold for relieving pain, clearing away heat-damp and promoting diuresis, eliminating the pathogens from the lung sending down the abnormal ascending QI, stomach invigorating removing food stagnancy, warming middle-JIAO to send down the adverse QI altogether, can strengthen autoimmune function, finally reach the object of healing.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. cure the medicament of abdominal distention, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Evodiae 9-15, Phymatopsis griffithiana (Hook.) J. Sm. 7-16, Cortex Cinnamomi Burmannii 6-12, broken orchid root 10-15, Rhizoma Cynanchi Stauntonii 8-14 ， Radix Betae 11-15, Fructus Coriandri 9-14, Radix phoebes sheareri 7-15, Herba Strigae Asiaticae 8-12, Flos Caryophylli 10-16, Thunbergia fragrans Roxb. 8-17, Radix tetrapanacis Koch 6-14, Rhizoma et radix valerianae 9-13.
2. medicament of curing abdominal distention as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Evodiae 10-13, Phymatopsis griffithiana (Hook.) J. Sm. 11-14, Cortex Cinnamomi Burmannii 8-11, broken orchid root 12-14, Rhizoma Cynanchi Stauntonii 9-12 ， Radix Betae 12-14, Fructus Coriandri 10-13, Radix phoebes sheareri 10-13, Herba Strigae Asiaticae 9-11, Flos Caryophylli 12-15, Thunbergia fragrans Roxb. 10-15, Radix tetrapanacis Koch 8-12, Rhizoma et radix valerianae 10-12.
3. medicament of curing abdominal distention as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Evodiae 12, Phymatopsis griffithiana (Hook.) J. Sm. 13, Cortex Cinnamomi Burmannii 10, broken orchid root 13, Rhizoma Cynanchi Stauntonii 11 ， Radix Betae 13, Fructus Coriandri 12, Radix phoebes sheareri 11, Herba Strigae Asiaticae 10, Flos Caryophylli 14, Thunbergia fragrans Roxb. 12, Radix tetrapanacis Koch 11, Rhizoma et radix valerianae 11.
4. the medicament of the treatment abdominal distention as described in as arbitrary in claims 1 to 3, it is characterized in that, the medicament of this treatment abdominal distention is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 12-18 minute, takes out, smashs to pieces after cooling, and adds Fructus Coriandri weight 8-12 water doubly, decocts 30 minutes, leach medicinal liquid;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 150-180 mesh sieve;
(3) all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli are cleaned, put into pot, add 11 taste crude drug 4.8-6 water (preferably adding the water of 11 taste crude drug 5.2 times) doubly, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 20-30 minute (fire of preferably larding speech with literary allusions boils 26 minutes), leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste (preferably the supernatant being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, put into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 150-180 mesh sieve (preferred mistake 170 mesh sieve);
(5) by step (2) and the mixing of step (4) gained, make popular with pot, after its cooling, encapsulate often to wrap in 4g loading sterile bag, to obtain final product.
5. the medicament of the treatment abdominal distention as described in as arbitrary in claims 1 to 3, it is characterized in that, the medicament of this treatment abdominal distention is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 12-18 minute (preferred slow fire stir-fries 15 minutes), takes out, smashs to pieces after cooling, and adds Fructus Coriandri weight 8-12 water (preferably adding the water of Fructus Coriandri weight 11 times) doubly, decocts 30 minutes, leach medicinal liquid;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(3) all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli are cleaned, put into pot, add 11 taste crude drug 4.8-6 water (preferably adding the water of 11 taste crude drug 5.2 times) doubly, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 20-30 minute (fire of preferably larding speech with literary allusions boils 26 minutes), leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste (preferably the supernatant being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, put into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(5) by step (2) and the mixing of step (4) gained, with the general ball of rice vinegar, make the pill that particle diameter is 3mm, 40 DEG C of water content being dried to pill, lower than 2%, to obtain final product.
6. the medicament of the treatment abdominal distention as described in as arbitrary in claims 1 to 3, it is characterized in that, the medicament of this treatment abdominal distention is made pharmaceutically acceptable tablet, and the preparation method of described tablet is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 12-18 minute (preferred slow fire stir-fries 15 minutes), takes out, smashs to pieces after cooling, and adds Fructus Coriandri weight 8-12 water (preferably adding the water of Fructus Coriandri weight 11 times) doubly, decocts 30 minutes, leach medicinal liquid;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(3) all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli are cleaned, put into pot, add 11 taste crude drug 4.8-6 water (preferably adding the water of 11 taste crude drug 5.2 times) doubly, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 20-30 minute (fire of preferably larding speech with literary allusions boils 26 minutes), leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste (preferably the supernatant being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, put into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(5) by step (2) and the mixing of step (4) gained, stir, add 10% starch slurry, make soft material, with 14 mesh sieve wet granulars, 45 DEG C are dried to moisture less than 2%, are pressed into the tablet of the heavy 0.4g of every sheet, obtain final product.
7. the medicament of the treatment abdominal distention as described in as arbitrary in claims 1 to 3, it is characterized in that, the medicament of this treatment abdominal distention is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) getting Fructus Coriandri puts in pot, and slow fire stir-fries 12-18 minute (preferred slow fire stir-fries 15 minutes), takes out, smashs to pieces after cooling, and adds Fructus Coriandri weight 8-12 water (preferably adding the water of Fructus Coriandri weight 11 times) doubly, decocts 30 minutes, leach medicinal liquid;
(2) Flos Caryophylli is dried, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(3) all the other the 11 taste crude drug except Fructus Coriandri and Flos Caryophylli are cleaned, put into pot, add 11 taste crude drug 4.8-6 water (preferably adding the water of 11 taste crude drug 5.2 times) doubly, soak 40 minutes, intense fire boils, and fire of larding speech with literary allusions boils 20-30 minute (fire of preferably larding speech with literary allusions boils 26 minutes), leaches medicinal liquid;
(4) step (1) and step (3) gained medicinal liquid are merged, leave standstill 12 hours, the supernatant is condensed into the thick paste (preferably the supernatant being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, put into 65 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 100-140 mesh sieve (preferred mistake 130 mesh sieve);
(5) by step (2) and the mixing of step (4) gained, stir, add 10% starch slurry, make soft material, with 14 mesh sieve wet granulars, 45 DEG C are dried to moisture less than 2%, and dry granule is again through 14 mesh sieve granulate, and subpackage, sealing, packaging, to obtain final product.
8. the preparation method curing the medicament powder of abdominal distention as claimed in claim 4, is characterized in that, in step (1), slow fire stir-fries 15 minutes.
9. the preparation method curing the medicament powder of abdominal distention as claimed in claim 4, is characterized in that, add the water of Fructus Coriandri weight 11 times in step (1).
10. the preparation method curing the medicament powder of abdominal distention as claimed in claim 4, is characterized in that, crosses 170 mesh sieves in step (2).
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| CN105535770A (en) * | 2016-01-15 | 2016-05-04 | 夏放军 | Traditional Chinese medicine condensed decoction for treating abdominal distension and preparation method thereof |
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| CN105435068A (en) * | 2015-12-14 | 2016-03-30 | 迟岳峰 | Traditional Chinese medicine composition treating abdominal distension after belly operation |
| CN105535770A (en) * | 2016-01-15 | 2016-05-04 | 夏放军 | Traditional Chinese medicine condensed decoction for treating abdominal distension and preparation method thereof |
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