CN105031752A - Drainage system containing silver bactericide release sleeve - Google Patents

Drainage system containing silver bactericide release sleeve Download PDF

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Publication number
CN105031752A
CN105031752A CN201510447401.6A CN201510447401A CN105031752A CN 105031752 A CN105031752 A CN 105031752A CN 201510447401 A CN201510447401 A CN 201510447401A CN 105031752 A CN105031752 A CN 105031752A
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Prior art keywords
silver ion
silver
ion
drainage
antimicrobial agent
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CN201510447401.6A
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CN105031752B (en
Inventor
许均卫
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Cheng Pin Bio Tech Ltd Jiangsu
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Cheng Pin Bio Tech Ltd Jiangsu
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    • A61M1/0023
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84Drainage tubes; Aspiration tips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0056Catheters; Hollow probes characterised by structural features provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

Provided is a drainage system containing a silver bactericide release sleeve. The drainage system is characterized in that the drainage system comprises a drainage pipe (1), an anti-reflux valve (2), a silver bactericide release sleeve body (3), a cannula (4), a catheter (5) and a drainage bag (6); one end of the anti-reflux valve (2) is connected with the drainage pipe (1); the drainage pipe (1) is connected with the cannula (4) by means of the silver bactericide release sleeve body (3); and the cannula (4) is connected with the drainage bag (6). The drainage system containing the silver bactericide release sleeve has following beneficial effects: it is clinically indicated that the drainage system can decrease the rate of urinary tract infection (CAUTI) associated with an indwelling catheter at 53%; the system is capable of continuously preventing a biological membrane from being formed in a liquid channel of a urination system; and single therapy has the effective effect on microorganisms of all pathogenic urinary tracts.

Description

The drainage system of silver ion antibacterial releasing sleeve
Technical field
The present invention relates to medical drain antimicrobial technology field, especially a kind of drainage system of silver ion antibacterial releasing sleeve.
Background technology
Problem: medical care infections relating (HAI) is the 4th large cause of the death of the Western countries, is also one of global modal cause of the death.In west, the medical treatment and nursing infections relating of about 40% is urinary tract infection (UTI), and wherein majority occurs along with urinary tract intubation.
At acute (short-term) indwelling intubation, modal germ contamination source is by the tube chamber outer pathway between urethra and conduit.But the most serious urinary tract infection threatens the retrograde growth coming from high concentration antibacterial, the biomembranous urine collection system that antibacterial can not penetrate in formation is bred on the surface.
As shown in Figure 1, the antibacterial 9 in drainage-fluid 8 breeds, and form biomembrane at the inwall of drainage tube 1, conduit 5 and drainage bag 6, biomembrane contains a large amount of antibacterials, and these antibacterials can rise along the length of urination system in less than three days and enter in bladder.Antibacterials a large amount of in biomembrane can cause bacteriuria disease, symptomatic infection, bacteremia and septicemia fast.It is extremely important that pre-bacteriological protection gets back to human body drain tissue 7 (bladder).
Electron micrograph shows that uropathogen can move to urinal from mouth of urinating; To adhere, biomembranous form enters conduit and bladder by check valve and along pipeline of urinating.These biomembranous survival abilities explain the infection why floss hole, check-valves, vent plug and other equipment fail to prevent generation in tube chamber.
Therefore, the drug resistance of bacterial antibiotic treatment has caused healthcare givers to need to seek preventative equipment helping infection.
Summary of the invention
The object of the present invention is to provide a kind of drainage system of silver ion antibacterial releasing sleeve, to overcome above-mentioned defect, realize the effect suppressing the antibacterial bred on urine collection system or drain gathering system.
Technical scheme of the present invention is:
A kind of drainage system of silver ion antibacterial releasing sleeve, comprise drainage tube 1, inverse reflux valve 2, silver ion antimicrobial agent releasing sleeve 3, sleeve pipe 4, conduit 5 and drainage bag 6, described inverse reflux valve 2 one end is connected with drainage tube 1, drainage tube 1 is by silver ion antimicrobial agent releasing sleeve 3 joint sleeve 4, and sleeve pipe 4 is connected with drainage bag 6.
Described silver ion antimicrobial agent releasing sleeve 3 comprises silver ion antimicrobial agent releasing sleeve body 30, silver-ion antibiotic glass column 31 and muff joint 32, silver-ion antibiotic glass column 31 is arranged in silver ion antimicrobial agent releasing sleeve body 30, muff joint 32 is connected with silver ion antimicrobial agent releasing sleeve body 30 is airtight, silver ion antimicrobial agent releasing sleeve body 30 one end is connected with drainage tube 1, and muff joint 32 is connected with sleeve pipe 4.
Described silver ion antimicrobial agent releasing sleeve body 30 comprises drainage tube interface 33, leading-in end shunting wing plate 34 and silver ion antimicrobial agent release chamber 35, described drainage tube interface 33 is taper, drainage tube interface 33 inside is taper official road, its conical pipeline inwall is arranged multiple leading-in end shunting wing plate 34, be columniform silver ion antimicrobial agent release chamber 35 below drainage tube interface 33, in silver ion antimicrobial agent release chamber 35, place silver-ion antibiotic glass column 31.
Described leading-in end shunting wing plate 34 is triangle, and along drainage tube interface 33 radial distribution, and a limit of leading-in end shunting wing plate 34 and silver ion antimicrobial agent releasing sleeve body 30 centerline parallel.
Described muff joint 32 comprises telescopic joint body 36, sleeve connection body 37 and exit shunting wing plate 38, described sleeve connection body 37 and exit shunting wing plate 38 lay respectively at the two ends of muff joint 32, and exit shunting wing plate 38 is arranged on muff joint 32 inwall.
Described exit shunting wing plate 38 is along muff joint 32 radial distribution, and an exit shunting limit of wing plate 38 and the centerline parallel of muff joint 32.7
Described silver-ion antibiotic glass column 31 is cylindrical, and its inside is provided with through cavity 39.
The material of described silver-ion antibiotic glass column 31 is water-soluble glass, it comprises antimicrobial component described in antimicrobial component and comprises one in silver ion, copper ion, zinc ion, magnesium ion, tin ion or gallium ion, or antimicrobial component comprises the combination in any of mentioned component.
The invention has the beneficial effects as follows:
The drainage system of silver ion antibacterial releasing sleeve of the present invention can reduce inlying catheter associated urinary tract infections CAUTI through clinical proof and reach 53%.
The drainage system of silver ion antibacterial releasing sleeve of the present invention continues the formation of prevention biomembrane on urination system fluid passage.
The drainage system single therapy of silver ion antibacterial releasing sleeve of the present invention is effective to the microorganism of all pathogenicity urinary tracts.
The drainage system of silver ion antibacterial releasing sleeve of the present invention can reduce acute conduit through clinical proof and to be correlated with urinary tract infection.
The drainage system of regular use silver ion antibacterial of the present invention releasing sleeve can prevent from being formed the bacterial biof iotalm that may cause infecting.
The drainage system of silver ion antibacterial releasing sleeve of the present invention is applied widely, not only can be applied to urine drainage, can also be applied to the drain of other Organ and tissues.
Silver ion antimicrobial agent releasing sleeve of the present invention is according to fluid mechanical design, be provided with leading-in end shunting wing plate and exit shunting wing plate respectively, shunting evenly, effect is not by the impact of drain uninterrupted, the lasting slow release silver ion antimicrobial agent of silver-ion antibiotic glass column of the present invention, the silver ion content that the release that can maintain a long-term stability is enough, can not be fewer and feweri.
Simultaneously, employing cylindrical drum designs, greatly can increase the contact area with liquid, ensure to be contacted with draining fluids by silver ion antimicrobial agent evenly fully, silver-ion antibiotic glass column is water solublity, in use, while its outer cylinder surface amasss and reduces gradually, its inner periphery amasss equivalent and increases, and ensures that the gross area contacted with drainage-fluid keeps constant, achieves stable releasing effect.
Clinical effectiveness:
A joint study demonstrated the clinical efficacy of the drainage system of silver ion antibacterial releasing sleeve of the present invention.Closed system technology is all employ in the drainage system group of matched group and silver ion antibacterial releasing sleeve of the present invention.
Table 1. matched group and infection ratio contrast table of the present invention
Initial data shows that infection is reduced to 15.3% from 35.2% generally.Consider each center, sex and the possible difference between Therapeutic Method contrast and the present invention, after statistical correction, infection rate is reduced to 16.4%p=0.028 from 35.2%, have dropped 53%.
When result describes intubation in detail, urine is through the situation of 130 patients of sterilizing.Result shows, regardless of the baseline values at each center, infection rate is all decreased significantly.
Accompanying drawing explanation
Fig. 1 is the using state schematic diagram of the drainage system of prior art.
Fig. 2 is the using state schematic diagram of the drainage system of silver ion antibacterial releasing sleeve of the present invention.
Fig. 3 is the integral installation distribution structure schematic diagram of silver ion antimicrobial agent releasing sleeve of the present invention.
Fig. 4 is the stereo decomposing structural representation of silver ion antimicrobial agent releasing sleeve of the present invention.
Fig. 5 is the sectional structure schematic diagram of silver ion antimicrobial agent releasing sleeve body of the present invention.
Fig. 6 is the axial viewing angle constructions schematic diagram of silver ion antimicrobial agent releasing sleeve body of the present invention.
Fig. 7 is the sectional structure schematic diagram of muff joint of the present invention.
Fig. 8 is the axial viewing angle constructions schematic diagram of muff joint of the present invention.
Fig. 9 is the sectional structure schematic diagram of silver-ion antibiotic glass column of the present invention.
Figure 10 is point flow diagram of silver ion antimicrobial agent releasing sleeve of the present invention.
Figure 11 is the electron micrograph not adopting the colon bacillus in drainage bag of the present invention, guide passage and valve surface to breed.
Figure 12 adopts electron micrograph of the present invention, shows that the present invention can suppress the formation of biomembrane on drainage bag, inverse reflux valve and drainage line.
In figure: 1 is drainage tube, 2 is inverse reflux valve, 3 is silver ion antimicrobial agent releasing sleeve, 4 is sleeve pipe, 5 is conduit, 6 is drainage bag, 7 is human body drain tissue, 8 is drainage-fluid, 9 is antibacterial, 10 is silver-ion antibiotic film, 30 is silver ion antimicrobial agent releasing sleeve body, 31 is silver-ion antibiotic glass column, 32 is muff joint, 33 is drainage tube interface, 34 is leading-in end shunting wing plate, 35 is silver ion antimicrobial agent release chamber, 36 is telescopic joint body, 37 is sleeve connection body, 38 is exit shunting wing plate, 39 is cavity.
Detailed description of the invention
Below in conjunction with accompanying drawing, the invention will be further described:
As Fig. 3 to Figure 10, a kind of drainage system of silver ion antibacterial releasing sleeve, comprise drainage tube 1, inverse reflux valve 2, silver ion antimicrobial agent releasing sleeve 3, sleeve pipe 4, conduit 5 and drainage bag 6, described inverse reflux valve 2 one end is connected with drainage tube 1, drainage tube 1 is by silver ion antimicrobial agent releasing sleeve 3 joint sleeve 4, and sleeve pipe 4 is connected with drainage bag 6.
Silver ion antimicrobial agent releasing sleeve 3 comprises silver ion antimicrobial agent releasing sleeve body 30, silver-ion antibiotic glass column 31 and muff joint 32, silver-ion antibiotic glass column 31 is arranged in silver ion antimicrobial agent releasing sleeve body 30, muff joint 32 is connected with silver ion antimicrobial agent releasing sleeve body 30 is airtight, silver ion antimicrobial agent releasing sleeve body 30 one end is connected with drainage tube 1, and muff joint 32 is connected with sleeve pipe 4.
Silver ion antimicrobial agent releasing sleeve body 30 comprises drainage tube interface 33, leading-in end shunting wing plate 34 and silver ion antimicrobial agent release chamber 35, described drainage tube interface 33 is taper, drainage tube interface 33 inside is taper official road, its conical pipeline inwall is arranged multiple leading-in end shunting wing plate 34, be columniform silver ion antimicrobial agent release chamber 35 below drainage tube interface 33, in silver ion antimicrobial agent release chamber 35, place silver-ion antibiotic glass column 31.
Leading-in end shunting wing plate 34 is triangle, and along drainage tube interface 33 radial distribution, and a limit of leading-in end shunting wing plate 34 and silver ion antimicrobial agent releasing sleeve body 30 centerline parallel.
Muff joint 32 comprises telescopic joint body 36, sleeve connection body 37 and exit shunting wing plate 38, and described sleeve connection body 37 and exit shunting wing plate 38 lay respectively at the two ends of muff joint 32, and exit shunting wing plate 38 is arranged on muff joint 32 inwall.
Exit shunting wing plate 38 is along muff joint 32 radial distribution, and an exit shunting limit of wing plate 38 and the centerline parallel of muff joint 32.
Silver-ion antibiotic glass column 31 is cylindrical, and its inside is provided with through cavity 39.
The material of silver-ion antibiotic glass column 31 is water-soluble glass, and it comprises antimicrobial component, and described antimicrobial component comprises the one in silver ion, copper ion, zinc ion, magnesium ion, tin ion or gallium ion, or antimicrobial component comprises the combination in any of mentioned component.
As Figure 10, the liquid flowed through in drainage tube, silver ion antimicrobial agent release chamber 35 is flowed into after being introduced into end shunting wing plate 34 uniform divided flows, and fully contact with silver-ion antibiotic glass column 31 wherein, a separating liquid part flows through from the cavity 39 at silver-ion antibiotic glass column 31 center by silver-ion antibiotic glass column 31 further, remainder liquid flows through from the outer cylinder surface of silver-ion antibiotic glass column 31, realize fully contact, silver-ion antibiotic glass column 31 dissolves by liquid, antimicrobial component in silver-ion antibiotic glass column 31 is discharged into liquid by equivalent, liquid containing antimicrobial component is again by flowing into drainage bag 6. after the shunting of exit shunting wing plate 38
As Fig. 2, Figure 12, illustrate for drainage of urine, human body drain tissue 7 is bladder, and drainage-fluid 8 is urine.The present invention can form one deck silver-ion antibiotic film 10 at the inner surface of sleeve pipe 4, conduit 5 and drainage bag 6, stops biomembranous formation.
Figure 11 is the electron micrograph not adopting the colon bacillus in drainage bag of the present invention, guide passage and valve surface to breed.
Figure 12 adopts electron micrograph of the present invention, shows that the present invention can suppress the formation of biomembrane on drainage bag, inverse reflux valve and drainage line.
The present invention is not limited in the drain of urinary system, also goes in any drainage system and device.
Embodiment recited above is only be described the preferred embodiment of the present invention; not the spirit and scope of the present invention are limited; do not departing under design concept prerequisite of the present invention; the various modification that in this area, common engineers and technicians make technical scheme of the present invention and improvement; all should fall into protection scope of the present invention, the technology contents of request protection of the present invention is all recorded in detail in the claims.

Claims (8)

1. the drainage system of a silver ion antibacterial releasing sleeve, it is characterized in that comprising drainage tube (1), inverse reflux valve (2), silver ion antimicrobial agent releasing sleeve (3), sleeve pipe (4), conduit (5) and drainage bag (6), described inverse reflux valve (2) one end is connected with drainage tube (1), drainage tube (1) is by silver ion antimicrobial agent releasing sleeve (3) joint sleeve (4), and sleeve pipe (4) is connected with drainage bag (6).
2. the drainage system of silver ion antibacterial releasing sleeve according to claim 1, it is characterized in that described silver ion antimicrobial agent releasing sleeve (3) comprises silver ion antimicrobial agent releasing sleeve body (30), silver-ion antibiotic glass column (31) and muff joint (32), silver-ion antibiotic glass column (31) is arranged in silver ion antimicrobial agent releasing sleeve body (30), muff joint (32) is connected with silver ion antimicrobial agent releasing sleeve body (30) is airtight, silver ion antimicrobial agent releasing sleeve body (30) one end is connected with drainage tube (1), muff joint (32) is connected with sleeve pipe (4).
3. the drainage system of silver ion antibacterial releasing sleeve according to claim 2, it is characterized in that described silver ion antimicrobial agent releasing sleeve body (30) comprises drainage tube interface (33), leading-in end shunting wing plate (34) and silver ion antimicrobial agent release chamber (35), described drainage tube interface (33) is taper, drainage tube interface (33) inside is taper official road, its conical pipeline inwall is arranged multiple leading-in end shunting wing plate (34), drainage tube interface (33) below is columniform silver ion antimicrobial agent release chamber (35), silver-ion antibiotic glass column (31) is placed in silver ion antimicrobial agent release chamber (35).
4. the drainage system of silver ion antibacterial releasing sleeve according to claim 3, it is characterized in that described leading-in end shunting wing plate (34) is triangle, and along drainage tube interface (33) radial distribution, and a limit of leading-in end shunting wing plate (34) and silver ion antimicrobial agent releasing sleeve body (30) centerline parallel.
5. the drainage system of silver ion antibacterial releasing sleeve according to claim 2, it is characterized in that described muff joint (32) comprises telescopic joint body (36), sleeve connection body (37) and exit shunting wing plate (38), described sleeve connection body (37) and exit shunting wing plate (38) lay respectively at the two ends of muff joint (32), and exit shunting wing plate (38) is arranged on muff joint (32) inwall.
6. the drainage system of silver ion antibacterial releasing sleeve according to claim 5, it is characterized in that described exit shunting wing plate (38) is along muff joint (32) radial distribution, and a limit of exit shunting wing plate (38) and the centerline parallel of muff joint (32).7
7. the drainage system of silver ion antibacterial releasing sleeve according to claim 2, it is characterized in that described silver-ion antibiotic glass column (31) is for cylindrical, its inside is provided with through cavity (39).
8. the drainage system of silver ion antibacterial releasing sleeve according to claim 2, the material that it is characterized in that described silver-ion antibiotic glass column (31) is water-soluble glass, it comprises antimicrobial component, described antimicrobial component comprises the one in silver ion, copper ion, zinc ion, magnesium ion, tin ion or gallium ion, or antimicrobial component comprises the combination in any of mentioned component.
CN201510447401.6A 2015-07-27 2015-07-27 The drainage system of silver ion antiseptic releasing sleeve Active CN105031752B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109069791A (en) * 2016-03-14 2018-12-21 观察医学有限责任公司 Biomembrane in conduit system prevents part

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050004525A1 (en) * 2003-07-01 2005-01-06 Shantha Sarangapani Leg bad accessory
CN1597009A (en) * 2003-09-17 2005-03-23 邵贤斌 Nanometer antibacterial urinary catheter
JP2007332131A (en) * 2006-05-15 2007-12-27 Tottori Univ Gradually disintegrating antibacterial agent, antibacterial liquid by using the same and device for forming the antibacterial liquid
CN101815546A (en) * 2007-10-03 2010-08-25 艾斯特勒科技公司 Catheter receptacle provided with an antimicrobial compound
US20130245496A1 (en) * 2012-01-09 2013-09-19 Mark Edward Wells Urinary catheter anti-reflux and pathogen block device
CN204972409U (en) * 2015-07-27 2016-01-20 江苏诚品生物科技有限公司 Contain telescopic drainage system of silver ion antiseptic release

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050004525A1 (en) * 2003-07-01 2005-01-06 Shantha Sarangapani Leg bad accessory
CN1597009A (en) * 2003-09-17 2005-03-23 邵贤斌 Nanometer antibacterial urinary catheter
JP2007332131A (en) * 2006-05-15 2007-12-27 Tottori Univ Gradually disintegrating antibacterial agent, antibacterial liquid by using the same and device for forming the antibacterial liquid
CN101815546A (en) * 2007-10-03 2010-08-25 艾斯特勒科技公司 Catheter receptacle provided with an antimicrobial compound
US20130245496A1 (en) * 2012-01-09 2013-09-19 Mark Edward Wells Urinary catheter anti-reflux and pathogen block device
CN204972409U (en) * 2015-07-27 2016-01-20 江苏诚品生物科技有限公司 Contain telescopic drainage system of silver ion antiseptic release

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109069791A (en) * 2016-03-14 2018-12-21 观察医学有限责任公司 Biomembrane in conduit system prevents part
CN109069791B (en) * 2016-03-14 2021-03-26 观察医学有限责任公司 Biofilm prevention element in a catheter system
US11213651B2 (en) 2016-03-14 2022-01-04 Observe Medical Aps Biofilm prevention in catheter systems

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