CN104998199A - Composite for treating various types of cancer - Google Patents

Abstract

The invention discloses a composite for treating various types of cancer. The composite is composed of moringa oleifera roots, moringa oleifera leaves, wild red-rooted salvia roots, bear gall powder, semen armeniacae amarae, sculellaria barbata, common peony roots, curcuma zedoary, pseudo-ginseng, ternate buttercup roots, liquorice and dendrobe. The composite is effective in shrinking lumps, controlling the transference, relieving pains, stabilizing the illness state, prolonging the lifetime and curing the cancer within a short period. The composite is clinically used for treating intestinal cancer, liver cancer, uterine cancer, bone cancer, brain cancer, gastric cancer, esophagus cancer and hemangioma, and the remarkable curative effect can be achieved.

Description

The compositions for the treatment of kinds cancer

Technical field

The invention belongs to field of medicaments, relate to a kind of compositions, said composition has good therapeutic effect to kinds cancer.

Background technology

Cancer, also known as malignant tumor, is commonly encountered diseases and the frequently-occurring disease of serious harm human health.In cancer, also do not find special therapy at present, for the generation of transfer of invasion and attack how controlling cancer, be still in the preliminary research stage.Modern medicine is extremely rare for the Therapeutic Method of cancer, and the life cycle that effectively can extend patient has been just be considered to more effective therapeutic effect.

Why fearful cancer is, be its have many as autonomy, aggressive, transitivity, abnormal differentiation, lose the biological properties such as contact inhibition.But endangering maximum is its aggressive and transitivity, and namely cancerous cell is taken to another away from position or organ by Lymph flow, blood flow, continues survival and flourish there, forms the overall process with the secondary tumor of primary tumor same-type.

Causing the morbidity of cancer to have the factor of exopathogenic factor and endogenous cause of ill two aspect, the dietary habit that its exopathogenic factor is mainly bad, as often eaten Pickles, the food that goes mouldy, food roasting and excessively edible acidic food, forming acidic physique etc.; Bad life habits is also the one of the main reasons causing cancer as indulged in excessive drinking excessively, smoking, stay up late; In addition, as the environmental pollutions such as atmospheric pollution, pollution of waterhead, pollution by pesticides also can direct cause cancer.Cause mainly gloomy, the anxious state of mind of mood of the endogenous cause of ill of cancer, stress, love angry.Because above reason carries out pessimal stimulation to human body information conducting system, thus cause gene mutation, cause new first portion cell to form the cancerous cell system of overgrowing, just become cancer.

In the early stage non-diffusion phase of cancer, had an opportunity by operative treatment, this depends on early stage examination and finds, because cancer inspection is in early days more difficult, majority also seldom do screening for cancer in daily health check-up, and the discovery therefore for early-stage cancer is more limited.Arrive the pernicious period that tumor expands match, conventional embolic chemotherapy, very big to the injury of health, the great pain making patient endure chemicotherapy to the fullest extent to bring, but therapeutic effect is also very limited.The expense for the treatment of of cancer costliness causes compatriots due to illness to cause poor major reason.In addition, treat the side effect profiles analysis produced from modern Western medicine, radiotherapy consumption impairment of QI is cloudy, belongs to the heresy of pyretic toxicity; Chemotherapy damages spleen, being impairment of the kidney belongs to cold-evil; Targeted therapy causes diarrhoea, erythra, belongs to the card of severe pathogenic cold refusing yang.Therefore, for through chemotherapy or the patient of radiotherapy too much course for the treatment of, corresponding Chinese traditional treatment method should be taked according to the character of poison.

Chinese medicine is of long standing and well established, and the understanding for cancer is also very unique.The traditional Chinese medical science is thought, human-body viscera function is normal, and QI and blood fills, and healthy energy is vigorous, and pathogenic factor is just difficult to invade, even if pathogen invasion, then healthy energy must rise and resist it, and tumor is just difficult to occur, and cancer would not occur.The traditional Chinese medical science is for the definition of malignant tumor: positive QI-insufficiency, causes the pathogens such as expectorant is turbid, blood stasis, tumor poison to be cemented in the lump formed in body.In neoplastic process, tumor poison plays a crucial role, the function that tumor poison tool attracts the pathological products such as the expectorant stasis of blood to assemble.Benign tumor, tumor poison is slight, and the expectorant stasis of blood that institute gather is healthy energy removing just, tumor long-term stability.Malignant tumor, tumor poison is heavier, and the ability of the poly-expectorant stasis of blood of poison exceedes the Scavenging activity of healthy energy, and tumor constantly grows.Although theory of Chinese medical science understanding is more, for the treatment of cancer, still rarely has wonderful recipe.

The present invention inherits the multiple general plan of traditional medicine for cancer research and treatment, provide a kind of compositions, all obvious to kinds cancer effect, clinical practice is in the treatment of all kinds of each phase cancer patient, its effect can reduce lump in a short time, control is shifted, palliate the agonizing sufferings, stablize the state of an illness, extend life cycle, even reaches clinical cure.

Technology contents

The object of this invention is to provide a kind of compositions various cancer all to therapeutic effect, clinical practice, in the treatment of all kinds of each phase cancer patient, has good curative effect.

The compositions that the present invention treats kinds cancer is made up of following Chinese medicine ingredients:

Moringa root, leaf of Moringa, wild loyal heart, Fel Ursi powder, Semen Armeniacae Amarum, Herba Scutellariae Barbatae, Radix Paeoniae Rubra, three spirits, Rhizoma Curcumae, Radix Notoginseng, Radix Ranunculi Ternati, Radix Glycyrrhizae, Herba Dendrobii.

The each Ingredients Weight proportioning of compositions that the present invention treats kinds cancer is:

Moringa root 15 parts, leaf of Moringa 20 parts, Radix Salviae simplicifoliae 9 parts, Fel Ursi powder 3 parts, Semen Armeniacae Amarum 2 parts, Herba Scutellariae Barbatae 10 parts, Radix Paeoniae Rubra 12 parts, three spirits 9 parts, Rhizoma Curcumae 11 parts, 15 parts, Radix Notoginseng, Radix Ranunculi Ternati 8 parts, 20 parts, Radix Glycyrrhizae, Herba Dendrobii 17 parts.

The method for preparing of the compositions of Therapeutic cancer of the present invention is:

(1) use as decoction, add 8-10 times amount clear water, intense fire changes slow fire into and continues decoction 30 minutes after boiling, cooling, and elimination medicinal residues are drunk, and every day sooner or later respectively once, drinks 200-300ml respectively depending on state of an illness weight at every turn, drinks after meal.

(2) use as powder, get recipe quantity compositions medical material after concocting, dry, pulverizing, crosses 100 mesh sieves, sterilization packaging, and every preparation unit is containing 10 grams of powders.Every day 4 times, each 10 grams, point early, middle and late, night takes.

Except traditional decoction, powder, the present composition can make the oral formulations such as tablet, capsule, solution, pill and injection and the form of administration such as externally used paste, patch according to pharmaceutics common method.

The therapeutic domain of compositions of the present invention is wide, all has significant curative effect for intestinal cancer, hepatocarcinoma, uterus carcinoma, osteocarcinoma, the brain cancer, gastric cancer, esophageal carcinoma, hemangioma.

The theories of Chinese materia medica of compositions institute of the present invention foundation is the heightened awareness of Traditional Chinese Medicine for tumor, cancer, the traditional Chinese medical science thinks that cancer pathogenesis comes from following situation: 1, positive QI-insufficiency, disturbance in functioning of QI, is difficult to effectively get rid of the metabolite in body and external toxin, causes poison to accumulate in body.2, positive QI-insufficiency, transporting is not good for, and takes in diet and effectively can not change nutrient substance into, the generation of renvoi expectorant (turbid).3, positive QI-insufficiency, promoting the circulation of blood, takes the photograph the function reduction of blood, and cause stopping in blood stasis, venation hindered by poison, produces blood stasis equally.4, phlegm stagnation in collateral, stagnant through vapour lock, internal organs contact imbalance, allomeric function declines, and shows as positive QI-insufficiency; Phlegm stagnation in collateral, gasification (metabolism) path is obstructed, and toxin expelling efficiency declines, and causes toxin to accumulate.5, tumor poison is independently virulence factor, and its concept is distinguished to some extent with traditional " pole of heresy just becomes poison ".Tumor hair growth promoting is centered by tumor poison, and the function that tumor poison tool attracts the expectorant stasis of blood to assemble, poison is more contained, and gravitation is stronger, and tumor growth rate is faster.6, treating the poisonous disease with poisonous drugs method (radiotherapy, chemotherapy comprise targeted therapy) is while treatment tumor, has the worry increasing the weight of tumor poison.

The stagnation of QI expectorant blood coagulation stasis of blood is the key of formation of cancer, and " Ling Shu Miraculous Pivot or Divine Axis all kinds of diseases and ailments begin raw " points out: do not fall apart in blood coagulation is accumulate ... and do not go and long-pending all one-tenth.Wang Qingren is pointed out: caking person, and blood that must be tangible also.Blood catches cold, and condense in bulk, and blood is heated, and decocts in bulk.The resistance of expectorant ecchymosis is that the important of cancer wants pathogenesis, applies eliminating evil therapy, must open the outlet of heresy.Gu Fuzheng gas is that the success or failure of Therapeutic cancer are crucial.Righting is this, " people lives without a break ", and " gas " exists people, and " gas " people of going out dies.The gas of nephrons comes from congenital heredity, the life span of vigour decider, and vigour can not be supplemented in the day after tomorrow, consumes vigour excessively and directly shortens the life-span.Spleen and stomach function will be not enough the day after tomorrow, positive QI-insufficiency, and the physiological function of human body can not coordinated operation, can increase the weight of vigour on the one hand and overrun, on the other hand due to the frequent intrusion of disease, more accelerate the consumption of vigour.Therefore, strengthening the body resistance, payes attention to the gas of spleen and stomach function, protection nephrons, impels that gasification is normal, mechanism of qi is normal, astringency inducing is normal, thus cuts off the source of the expectorant stasis of blood, is one of approach stoping cancer growth.Treatment of cancer is for the purpose of the life maintaining patient, and the modern times have wound therapy (operation, radiotherapy, chemotherapy, radio frequency, targeting) to damage wound to healthy energy, and cancer sustainable development also has damage to healthy energy, weigh both degree of injury.Herba Dendrobii energy reinforcing stomach reg fluid, strengthen the spleen and stomach, nourishing YIN and clearing away heat, health invigorating.

Zoopery confirms, righting medicine such as Fructus Ligustri Lucidi, the Fructus Lycii etc. of current conventional Therapeutic cancer have the effect significantly urging growth of cancers in vitro.In addition, cancer cell has the feature of infinite multiplication, and normal cell stops propagation automatically when returning to a certain degree, therefore, when healthy energy is not empty, for a long time, widely applies righting medicine unhelpful to the body that negative and positive are in a basic balance, have the worry promoting growth of cancers on the contrary.Herba Dendrobii, Radix Salviae simplicifoliae coordinate then invigorating the spleen and benefiting QI, turn round and look at gas righting effect well a lot.

It is long that cancer has disease time, the feature of pathology complexity, and the treatment of cancer needs long-time conditioning, is elder generation especially with toxin expelling.Due to the root that tumor poison is cancer return, transfer, therefore, recover completely in the healthy energy of cancer patient, now the emphasis of long term maintenance therapy should be placed on toxin expelling, press down poison, antitoxin on, be simultaneously suitably aided with righting.Radix Paeoniae Rubra, Herba Scutellariae Barbatae, Radix Ranunculi Ternati have effect of heat radiation removing toxic substances, blood circulation promoting and blood stasis dispelling, coordinate Herba Dendrobii, Radix Salviae simplicifoliae strengthening the body resistance, have good effects for lasting toxin expelling is antitoxin.

The traditional Chinese medical science is thought, YIN nourishing primordial QI reinforcing is also wanted in treatment of cancer, ignites descending.Cancer patient, the sign of common " upper excess and lower deficiency ", show as the symptoms such as paroxysm is scorching, short-tempered, flushed face with red ears, uneasy sleeping at night, chills and pain of the waist and kness, lower limbs edema, Chinese medical discrimination is pathogenic fire derived from stagnation of liver-QI, deficiency of kidney-YIN, stagnation of liver-QI is mark, deficiency of the kidney is this, and large agent application depressed liver-energy dispersing and QI regulating medicine can rescue the anxious of a period of time but permanent application can increase the weight of the state of an illness.Therefore, these type of disease feelings should be basic with nourishing kidney nourishing YIN, are aided with the medicine of depressed liver-energy dispersing and QI regulating, just can tackle the problem at its root.We adopt Moringa root leaf, coordinate Fel Ursi powder, Semen Armeniacae Amarum maintenance Liver and kidney.

Cancer is chronic disease, and generally from falling ill to clarifying a diagnosis, the course of disease may have 10 ~ 20 years.Pathogen usually intruding into collateral in protracted disease, prolonged illness at blood, therefore in the how evil poison of cancer is embedded in, general promoting flow of QI and blood is difficult to prove effective, cancer poison Nitrosamines, and the cancer of many end-stage patients is after radiotherapy and the chemotherapy of multiple course for the treatment of, the oncocyte toxicity of surviving is powerful, almost all tolerates all chemicalses.If now patient falls back in the traditional Chinese medical science, if healthy energy is still filled and endogenous toxin is powerful, for the evil gesture of folding, heavy prescription must be used.When with promoting flow of QI and blood medicine, add into Drug Prepared from Insects.The method risk of this treating the poisonous disease with poisonous drugs is comparatively large, since Moringa is as anticancer health-care drug dependence, obtains large-scale popularization application, and core part of the present invention is exactly use Moringa root leaf to instead of the larger Drug Prepared from Insects of toxicity.

Combine it, the present composition selects the pharmacologically active basis of medical material to be:

Moringa root is acrid in the mouth, slightly warm in nature, nontoxic.Moringa root has the effect of dampness removing, spleen invigorating, wind dispelling, antiinflammatory, stomach invigorating, diuresis, tonifying YANG.For controlling headache, dizzy, asthma, stomatitis, pharyngolaryngitis, flatulence, gastrointestinal convulsion, neurasthenia, hypertension, diabetes, vitamin C deficiency, vitamin B1 deficiency, dermatosis, pus infections and various cancer.Ayurvedic medicine treats ulcer and tumor with Moringa tree root.With leaf of Moringa treatment ulcer, tumor and research report in closely also quick-fried increasing; Aktar and Ahmad thinks that bud can control ulcer, and the research team of the people such as Murakami and Guevara confirms that leaf of Moringa has anticancer effect.The composition being developed to cancer therapy drug potentiality is had in India, at present at the food research gained (lnstituteofFoodResearch of Britain, Norwich, UK) 4-(a '-L-Rhamnopyrano-syloxy)-benxyl glucosinolateh and 3-Hydrosy is had in testing, 4 (a '-L-Rhamnopyranosyloxy) benzylglucosinolate etc.

Leaf of Moringa, leaf of Moringa has dehumidifying, cold relieving, the effect of tonifying YANG, diuresis, detumescence.Containing abundant nutrition, homovitamin A, B, B1, B2, B3, c1, E, high protein, high microsteping.Wherein containing six kinds of mineral elements (calcium, magnesium, phosphorus, potassium, sodium, sulfur), five kinds of trace element (zinc, copper, ferrum, manganese, selenium) and 11 kinds of essential amino acids.Aminoacid is the important element of activating cell, enhancing immunity, strengthening sexuality.Think that Moringa tree can prevention of various diseases according to Hindu medicine 1,100 checking, be medically applied to the diseases such as diabetes, hypertension, dermatosis, anemia, skeleton, anti-melancholy, arthritis, digestive organs, tumor.

The methanol of leaf of Moringa, ether or chloroform extraction thing have good control effects to dermatophytes.Dermatophytes is the pathogen of tinea pedis, leaf of Moringa extract reaches 10mg/mL concentration just can be suppressed, dermatophytes Trichophyton mentagrophyteS and T.Simmii (Ind.J.Pharmac.9 (4): 269-272,1977 then can be killed more than 20mg/mL.Tremble with dry leaf of Moringa powder and close the medicine for external use that vaseline or hydrophilic ointment can be used as tinea pedis.Pakistani researcher is separated from leaf of Moringa, be purified into three kinds of water miscible small molecular weight proteins, there is inhibition to various bacteria, comprise escherichia coli, Ke Leishi produces chlorine bacillus, Ke Leishi pneumobacillus, staphylococcus aureus, bacillus subtilis, melanomyces, yellow bacterium and penicillium.United States Patent (USP) the 6th, 383, No. 495 cold liquid, Aloe juice, the refreshing Herba Ocimi (Herba Ocimi Pilosi)s introduced with dry leaf of Moringa and lantern tridax leaf, quintessence oil, Olibanum (Gumolibanum) etc. makes ointment, can can send out in order to treatment and treat and have the eczema of burning sensation, also can with removing cornified dead bark, as clavus etc.The anti-inflammatory effects of visible Moringa tree has made the fine chemistry industry boundary of medicine from traditional folk custom therapy progress to extract component.And the initial tumor stage of cancer also be mostly caused by various inflammation, therefore, effect of anti-inflammation is the basis of Therapeutic cancer.

Radix Salviae simplicifoliae, bitter in the mouth, micro-pungent, cold nature; GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, removing heat from blood is subsided a swelling.Radix Salviae simplicifoliae energy coronary artery dilator, increase coronary blood-flow volume, improve core ischemia, infarction and cardiac function, the adjustment rhythm of the heart, and can expand peripheral blood vessel, improves microcirculation; There is anticoagulant, promote fibrinolytic, anticoagulant, the effect of inhibition thrombosis; Energy blood fat reducing, can suppress or alleviate liver, cytopathy, necrosis and inflammatory reaction, promotes liver, cell regeneration, and has anti-fibrosis effect; The hypoxia-bearing capability of body can be improved; The reparation of tissue can be promoted, accelerate the healing of fracture, erythrocyte and hemoglobin return period can be shortened, make ceticulocytosis; There is suppression to various bacteria and tubercule bacillus, have the effect suppressing nervus centralis.Strengthen immunity in addition, reduce blood glucose and antitumor action.Radix Salviae simplicifoliae is different from common Radix Salviae Miltiorrhizae, is the high-quality Radix Salviae Miltiorrhizae coming from the plantation of wild Radix Salviae Miltiorrhizae seed cultivation, the effective ingredient of its imitative wild Radix Salviae Miltiorrhizae, more taller than wild Radix Salviae Miltiorrhizae go out nearly 1 times.

Fel Ursi powder, cold in nature, nontoxic, bitter in the mouth Hui Tian, the micro-raw meat of gas delicate fragrance.1. blood pressure lowering, coronary artery dilator, increases coronary flow, strengthens myocardial contraction and regulates Arrhythmia.2. antibacterial, antiinflammatory, antiallergic, function of gallbladder promoting, Detoxication, have protective effect to hepatocyte, and can relax ductus choledochus and Oddi's sphincter, promote bile secretion.3. function of gallbladder promoting, litholytic effect.Can Biosynthesis of cholesterol be reduced, and can choleresis be increased, improve the ability of bile dissolving cholesterol, reduce gall-stone formation rate.4. calmness, analgesia, convulsion, spasmolysis.5. blood fat reducing, hypoglycemic activity, can reduce blood viscosity and erythrocyte aggregation index and platelet adhesion rate, inhibition thrombosis.6. antitussive, eliminate the phlegm, relieving asthma, antiinflammation.7. antibacterial, pain relieving, detumescence, improving eyesight, removing nebula effect.8. suppress newborn acid in body to generate, in acceleration bodies, fatigue substances excretion, has resisting fatigue, the effect of regaining one's strength.

Semen Armeniacae Amarum, bitter in the mouth, tepor, slightly poisonous.Return liver, large intestine channel.Sending down the abnormal ascending QI relieving cough and asthma, loosening bowel to relieve constipation.Early in the twentieth century amygdaloside is separated first from Semen Armeniacae Amarum, and amygdaloside is used for controlling Semen Armeniacae Amarum in the U.S. and treats tumor by nineteen twenty first.Start amygdaloside from the 1950's to be used for treating tumor in the national widespread such as the U.S., Mexico, amygdaloside is a kind of laetrile, has the effect of prevention and therapy tumor.The suppression ratio of thick agent to Human cervical tumor JTC-26 strain of assistant Teng Zhaoyan (1979) report Semen Armeniacae Amarum hot water extract is 50%-70%.The result of study of Fang Wenlong etc. (1986) shows, Semen Armeniacae Amarum extract lumbar injection or gavage, is 61.7%-77.1% to the suppression ratio of hepatocarcinoma and sarcoma 180.First-class (1987) result of the test of car literary composition shows, the antitumor effective ingredient extracted from Semen Armeniacae Amarum is to the injection of transplanted hepatoma mouse peritoneal 300mg/kg, 400mg/kg, 600mg/kg, and its tumor control rate is respectively 72.0%, 60.8%, 51.0%.Freely absorb Semen Armeniacae Amarum to mice, the growth of ehrlich ascites cell can be suppressed, make life span extension.Also have report amygdaloside can prevent and treat the hepatocarcinoma of N-nitrosodimethylamine induction, tumor stove is reduced.

Herba Scutellariae Barbatae, acrid in the mouth, hardship, cold in nature.Return lung meridian; Liver Channel; Kidney channel.All herbal medicine, has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the function such as anticancer." Quanzhou book on Chinese herbal medicine ": heat clearing away, removing toxic substances, method wind, loose blood, circulation of qi promoting, diuretic, dredging collateral, removing blood stasis with potent drugs, pain relieving.Main stranguria with blood for oral administration, spits blood, epistaxis; External smelting venom, carbuncle, furuncle, innominate toxic swelling.Guangzhou army " conventional Chinese herbal medicine handbook ": heat-clearing and toxic substances removing.For cancerly see the effect improving symptom; Appendicitis, hepatitis.Chengdu " conventional herbtherapy handbook ": treatment of esophagus cancer, gastric cancer, uterus carcinoma.These product contain alkaloid, flavonoid glycoside, steroidal and phenols, tannin etc.Rivularin contained by it is a kind of flavone compound (2,5-dihydroxy-6,7,8-trimethoxy flavone), in addition, also have another two kinds of flavone compound Chinese Radix Scutellariae elements (5,7-dihydroxy-8 methoxy flavone) and 5-hydroxyl-7,8-dimethoxy flavone.Zoopery confirms, Herba Scutellariae Barbatae all has certain inhibitory action to sarcoma 180, ehrlich carcinoma, cerebroma 22 etc.Japanese scholars finds that there is 88 kinds of Chinese medicines to the suppression ratio of tumor cell proliferation more than 90% when making antitumor activity screening by experiment in vitro to 800 kinds of Chinese medicines, wherein Herba Scutellariae Barbatae reaches 100% to JTc-26 oncocyte extracorporeal inhibiting rate, and it is then only 50% to Normocellular suppression ratio.Finding when observing the clinical antineoplastic curative effect of these Chinese medicines, even the late tumor to the weary art for the treatment of, being also improved symptom, Tumor suppression propagation and extending the effect of patient vitals.Experiment also confirms, use methylene blue test tube method, BANJILIAN has slight inhibitory action to Acute granulocytic leukemia cell; Use Cellular respiration method, 75% is greater than to Acute granulocytic leukemia cell and suppression ratio.Sculellaria barbata formulation also all has certain inhibitory action [5] except antitumaous effect to animal tumors such as W256.U14.S186.EAC, ESC, antibacterial, diuresis, the cough-relieving in addition of these product, the multiple pharmacological effect such as to relieving asthma.Herba Scutellariae Barbatae is in clinical anticancer, and application is very extensive, and for the treatment of kinds of tumors, clinical have a large amount of report, do not enumerate herein.

Radix Paeoniae Rubra, bitter in the mouth, cold nature.Return Liver Channel.There is the function of clearing away heat and cooling blood, eliminating stasis to stop pain.Raw Radix Paeoniae Rubra wins with clearing away heat and cooling blood power.The fever of the body being used for the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases is hemorrhage, conjunctival congestion and swelling pain, carbuncle sore tumefacting virus." property of medicine opinion ": control pathogen of the lung gas, Fu Zhong Xu pain, vim and vigour are gathered, and logical a surname's internal organs gather around gas, control evil pain deteriorated blood, and disease bone heat time main, strong the five internal organs, the kidney invigorating gas, controls trusted subordinate's heavily fortified point swollen, and married woman's blood closes obstructed, and repercussive blood can lose pus.

Rhizoma Curcumae, aromatic turmeric oil preparation has the growth of the multiple tumor strains such as the L615 leukemia of Mouse Ehrlich Carcinoma Cells, 615 mouse inbred liness and ascites hepatoma cells in vitro and obviously suppresses and destruction.100% Ah Rhizoma Curcumae injection 0.3-0.5ml injects to mouse peritoneal, to euphorbia egg decoctum.There is good curative effect, inhibitory rate more than 50%.The monomer obtained from Rhizoma Curcumae volatile oil, when curcumenol and curdione 75mg/kg subcutaneous injection, to murine sarcoma S37, cervical carcinomal U14, ehrlich carcinoma (ECA) all have higher suppression ratio, tumor does not obviously reduce person, visible tumor tissue surrounding annulus cytosis, inside has one deck lymphocyte, phagocyte to surround the immunoreation such as tumor cell and occurs.Under Electronic Speculum, treatment group tumors cells show nucleo-cytoplasmic ratio reduces, and core profile trend is normal, and chromatin, kernel and interchromatin granule quantity reduce, therefore think that the nuclear metabolism of Rhizoma Curcumae to murine sarcoma has inhibitory action.In vitro tests proves that curcumenol and curdione have obvious destruction to ehrlich ascites cell, can make its degeneration necrosis.The Oleum Curcumae injection of variable concentrations all has significantly directly destruction to oncocyte, and have the feature that effect is fast and strong, oncocyte number is more, kill 90% the liquor strength needed for oncocyte larger.The existing direct effect of mode of Rhizoma Curcumae antitumaous effect, also has the immunoreation of host to participate in.Clinically make intratumoral injection cervical cancer with Oleum Curcumae, after treatment, visible tumor tissue necrosis comes off, and local lymphocytes infiltrates, and some cases lump disappears, and cervix uteri is smooth, and prompting Rhizoma Curcumae has the effect of directly killing oncocyte.The principle of Rhizoma Curcumae antitumaous effect, outside the direct cytotoxicity of Oleum Curcumae decapacitation, can also strengthen oncocyte immunogenicity, thus brings out or promote that body is to the immunological rejection of tumor, experiment proof ECA and L615 of Rhizoma Curcumae process.Tumor vaccine carries out active immunity, and Some Animals really can be made to obtain obvious protective effect.Good curative effect is had, in addition, for curing digestive system tumor, as hepatocarcinoma, cancer of pancreas, intestinal cancer, abdominal cavity malignant lymphoma etc. with the local tumor body administration of Rhizoma Curcumae preparation or Venous Arterial intravasal administration.The curcumenol injection gone on the market: function is anticancer.For various cancer.Intramuscular injection, each 5-10ml, every day 1 time.[" pharmacy circular " 1980,15 (11): ll].

Radix Notoginseng, sweet in the mouth, micro-hardship, warm in nature.Return Liver Channel, stomach warp, heart channel, lung meridian, large intestine channel.Hemostasis, loose blood, analgesic therapy.Congestive edema is flutterred, thoracic obstruction angor ， mass in the abdomen for falling; Blood stasis amenorrhea; Dysmenorrhea; Puerperal, stasis of blood the moon was suffered from abdominal pain; Sore, carbuncle and painful swelling.Ginsenoside Rh1 has inhibitory action to Hepatoma Cells In Vitro.The ginsenoside Rh contained in Radix Notoginseng can suppress the growth of murine melanoma (B16), and effect is in concentration-dependent relation.Arasaponin is when existing with canavaline (ConA) or phytohaemagglutinin (PHA) simultaneously, and the mouse boosting cell of its induction has stronger anti-tumor activity, may be the kill capability that PNS enhances the immunocyte be activated.

Radix Ranunculi Ternati, sweet in the mouth, pungent, tepor.Return liver, lung meridian.Dissipating phlegm and resolving masses, removing toxic substances and promoting subsidence of swelling.Wang Aiwu etc. inquire into the different extracts of Radix Ranunculi Ternati to the effect of the tumor cell of In vitro culture, adopt systematic solvent extraction to extract Radix Ranunculi Ternati saponin and polysaccharide, use MTT and Colony forming laboratory method to observe the impact on the euphorbia egg decoctum of In vitro culture, ehrlich ascites tumor EAC and MCF-7 cell strainHJ2mm of the saponin of variable concentrations and polysaccharide.Found that Radix Ranunculi Ternati saponin and polysaccharide all have impact in various degree to the growth of three kinds of tumor cell lines and Colony forming, saponin dosage and tumour inhibiting rate and Colony forming correlation significantly, and polysaccharide there is an optium concentration.The research such as Zhou Li finds that the ethanol extract of Radix Ranunculi Ternati has stronger induction role to tumor necrosis factor (TNF), and in screened 36 kinds of Chinese herbal medicine, Radix Ranunculi Ternati (ethanol extract of 70%) production of TNF induced effect is the strongest.Jiang Shi reports, adds that the wart soup that disappears is for oral administration controls thyroid tumor 50 example with liver cancer tablet (Radix Ranunculi Ternati compound recipe).Therapeutic outcome: recovery from illness 26 example.Effective 4 examples, take a turn for the better 17 examples, and invalid 3 examples, total effective rate is 94%, and average cure time is 28.5.Chen Shi reports, substantially just adds Radix Ranunculi Ternati, seed of Livistona chinensis R.Br. treats various malignant lymphoma 11 example with Chinese medicine, decoct or make pill and take orally, and coordinates application, obtains good therapeutic effect.Li Shi reports, to malignant lymphoma fever patient 68 example, all on dialectical basis, add Radix Ranunculi Ternati, Herba Solani Nigri etc., to improving, symptom curative effect is better.Young is reported, makes slow grain ball with Radix Ranunculi Ternati compound recipe (Mongolian gazelle, Radix Sophorae Flavescentis, Radix Ranunculi Ternati, Radix Angelicae Sinensis etc.), every ball containing crude drug amount 3g, every day 4.5 ~ 9g, maintenance dose 3 ~ 6g every day, treats slow grain patient 12 example altogether.Result complete incidence graph 6 example, partial rcsponse 1 example, progressive 4 examples, invalid 1 example, total effective rate is 91.7%; After treatment, leukocyte starts fall time is 20 ~ 42 days, and average 30 days, taking during leukopenia to 10 × below 109/L was 31 ~ 180 days, average 78.6 days.Zhang Shi also reports, (coated tablet made by Radix Ranunculi Ternati, Radix Sophorae Flavescentis, Radix Scutellariae etc. to make slow grain sheet by Radix Ranunculi Ternati compound recipe, every sheet is containing crude drug 0.25g), treatment chronic myelocytic leukemia 30 example, therapeutic dose is 5 ~ 7.5g every day, maintenance dose is 2.5 ~ 5g/d, several oral, and rotates for a long time with Western medicine Busulfan and use.The routine alone Busulfan treatment of matched group 28.Counting life cycle in result Chinese medicine and western medicine group is 61 months, and matched group is 40 months, significant difference (P < 0.01).Confirming to rotate slow grain sheet and Busulfan, to treat the more alone Busulfan therapeutic effect of slow grain good.Chen Shi reports, with the careless soup of compound recipe three (composition such as Herba Houttuyniae, Herba Agrimoniae, Radix Ranunculi Ternati) plus-minus treatment advanced lung cancer 95 example.Be decocted in water for oral dose, every day 1 dose.Total effective rate is 61.1% (58 example), and the cancer person of reducing 6 example, cancer stablizes 3 ~ 5 months person 32 examples, stablizes more than 6 months persons 15 example.Life cycle, more than 1 year 31 example, more than 2 years 7 examples, within more than 3 years, person 5 was routine less than 1 year person 52 example.Within more than 1 year, survival rate is 45.3%, and middle several life cycle is 11 months.In addition, Wang Shi reports, treats hysteromyoma 98 example, the blood stasis-eliminating and stagnation-dissipating medicine composition compound treatments such as medicinal Radix Ranunculi Ternati, result recovery from illness 64 example, effective, effective totally 28 examples, invalid 6 examples.Zhao Shi reports, treatment early, mid-term nasopharyngeal carcinoma, apply anticancer substantially square (composition such as Rhizoma Paridis, Rhizoma Arisaematis, Radix Ranunculi Ternati, Gekko Swinhonis) and close wuwei xiaodu drink and take orally, clinical have good therapeutic effect.Traditional Chinese medical science succession aspect: (1) Radix Ranunculi Ternati, Spica Prunellae, each 50g.Be decocted in water for oral dose, every day potion.Add XIAOJIN DAN, each 3g, every day 2 times.[Chinese medicine (traditional Chinese medical science) digest, 1996, (4)]; (2) Radix Ranunculi Ternati, Herba Houttuyniae, Herba Agrimoniae, Radix Codonopsis lanceolatae, Rhizoma Paridis, each 30g, Radix Asparagi 20g, each 15g of Rhizoma Pinelliae, Bulbus Fritillariae Thunbergii, Semen Lepidii (Semen Descurainiae) 12g, is decocted in water for oral dose, every day 1 dose.Divide 2 clothes.(" effect for cancer of anti-tumor Chinese medicine ").

Radix Glycyrrhizae, property is put down, and sweet in the mouth, returns 12 warps.There is removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, relieving cough and moistening lung, emergency is detoxified, and is in harmonious proportion hundred medicines.

Herba Dendrobii, sweet in the mouth, cold nature, returns stomach, kidney channel.Reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Except there being antipyretic effect, gastric secretion can be promoted, aid digestion, there is enhancing metabolism, outside the anti-ageing effect of waiting for a long time, also have Tumor suppression effect, modern medicine study confirms that Herba Dendrobii some cell to malignant tumor such as pulmonary carcinoma, ovarian cancer and promyelocytic leukemias has killing action, has stronger anti-tumor activity.The clinical auxiliary treatment for malignant tumor, can improve the symptom of tumor patient, alleviate the side effect of Radiotherapy chemotherapy, enhancing immunity, improves life quality, extends life span.

Research shows, only have when body obviously reduces the immunologic function of cancer or loses, cancer just can be taken advantage of a weak point.If when occurring from first cancerous cell just prophylaxis of cancer, almost can obtain the effect of 100%.These medicines can enhancing human body immunity function to reach anticancer growth, do not have side effects again simultaneously, its main direction, all for cancer anticancer while, enhancing human body immunity power, cures cancer completely to reach, the object of beat cancer.

The cancerous cell of effective ingredient to exception of these traditional medicines has congenital exclusiveness, and directly affects the life-information conducting system of the mankind.The interdependent flora of cancerous cell can be killed after active ingredient in these Chinese medicines enters human body, can promote that leukocyte generates rapidly and invigorates, and increase the function activation phagocyte of immunocyte with the speed of several times, suppress to kill cancerous cell.Particularly can generate new nitrogen tyrosine and collagen protein, these materials enjoy a lot to be attached on cancerous cell, and then cancerous cell are tightly wrapped suppression and kill.

In sum, these Chinese medicines directly can not only kill cancerous cell, the more important thing is that the active ingredient of these medicines can the normal vitality of human activin immediately, strengthen the immune system of human body, correct Information Conduction system and the brain centres dependent instruction system of Hemapoiesis.Thus make Hemapoiesis Information Conduction system recovery normal, make cerebral central nervous system send the Normocellular instruction of growth, stop sending the false command generating unnecessary cancerous cell, reach thorough destruction, eliminate cancerous cell generation system, prevention and radical cure cancer.It is also like this for having the morbidity of cancer family history crowd and controlling mechanism in advance.It is emphasized that these Chinese medicines to just in forming process and the cancer of early origin there is the preventive effect of special treatment meaning.

The scope of application of anti-cancer composition of the present invention:

1, serious symptom cancer patient, taking its effect of this Chinese medicine formula can reduce lump in a short time, controls transfer and spreads, palliates the agonizing sufferings, stablizes the state of an illness, extends life cycle, improve life quality, even reach clinical cure, have the possibility of rehabilitation.

2, the cancer patient made a definite diagnosis is waited for, because need the wait of a period of time to the further diagnosis of pathology, at this moment should promptly take this Chinese medicine formula, immunity of organisms can be improved fast, the development of the stability contorting state of an illness, can realize the therapeutic effect of " prevention of diseae, see disease anti-rotation ".

3, preoperative cancer patient, takes this Chinese medicine formula and can soften and reduce lump, improve body function, reduces operation risk, makes patient steadily tide over average of operation periods.

4, postoperative cancer patient, takes this Chinese medicine formula and can kill remaining cancerous cell fast, prevents transfer, recurrence.

5, convalescent cancer patient, takes this Chinese medicine formula and can prevent remaining cancerous cell from staging a comeback, stop relapse and metastasis.

Leading reference: [1] tribute great waves, Ge Xinguo. the progress [J] of TCM on Tumor leukopenia after chemotherapy. Chinese medicine Leader, 2010,16 (12): 105; [2] Wang Lifang, Xu Zhenye. Chinese medicine malignant tumor and circular for confirmation medical science [J]. Chinese medicine academic periodical, 2005,23 (9): 1642; [3] Liu Xingan, Wang Wenping. Chinese medicine Advanced cancers outlines [J]. practical tcm internal medicine magazine, 2009,23 (7): 38; [4] Li Peifu. Chinese medicine is debated my opinion about curing oncoma. the academic conference of international Chinese medicine tumor, 2007,43; [5] Zhou Yiqiang. Chinese medicine is in the therapeutical effect of malignant tumor different phase and status. the academic conference of Chinese tumor & well-known doctor, 2008; [6] Wang Yong. TCM on Tumor clinical enter [J]. Anhui medicine, 2004,8 (3): 224; [7] Wang Jinan, Ou Yangxuenong. the status and prospects [J] of TCM on Tumor. Chinese medicine, 2008; [8] Li Weidong, Hua Baojin. different method for the treatment of general introduction [J] of Chinese medicine prevention tumor. Medical review, 2012,18 (2): 269; [9] Wu Dan, Li Hongzhi, Liu Jieting etc. treatment by Chinese herbs tumor research overview [J]. Mudanjiang Medical College's journal, 2011,32 (3): 72; [10] Liu Luming, Chen Zhen, Chen Peifeng. to the thinking [J] of blood-activating and stasis-removing treatment malignant tumor. Journal of Traditional Chinese Medicine, 2007,48 (9): 776.

Clinical efficacy

1. sample information

Apply this compositions and treat various cancer 63 example.Be out-patient for many years.Man 34 example in case, female 29 example, wherein age reckling 27 years old, the oldest person 92 years old.

2. Therapeutic Method

Observe the medication cycle according to conditions of patients, choose medical material in prescription ratio, make decoction or powder, take treatment by doctor's advice.

3. model case

(1) river, man, 58 years old.In March, 2005 is diagnosed as hemangioma and multiple card at local hospital, after cause apoplexy, western medical treatment is many for half a year, and cause health seriously to be got fat, breach appears in skin, can not leave the bed.Find me through acquaintance at the end of the same year, use the treatment of present composition powder, within one week, the state of an illness obviously alleviates, and within one month, be almost recovered, being used in conjunction two months can take care of oneself, and walks, runs, by bike etc. can be substantially the same with normal person.Follow up a case by regular visits to so far without any recurrence sign.

(2) Liu, man, 62 years old.Within 2006, suffer from esophageal carcinoma, bad at local hospital therapeutic effect, the state of an illness constantly worsens, and adopts present composition powder to treat in November, 2006, treats a month state of an illness and is clearly better, and treatment canceration in 52 days disappears substantially continuously, transference cure.Follow up a case by regular visits to and do not recur so far.And it is with suffering from the disease of this disease by because not adopting this therapy for treating in hospital, in Shanghai, tumour hospital is dead.

(3) Wang, man, 68 years old.In May, 2010 is diagnosed as gastric cancer at local hospital, and 9 centimeters, large tumor, is dispersed in little tumor in addition, invalid at local hospital western medical treatment, the state of an illness constantly increases the weight of, and then starts to adopt present composition decoction to treat in July, 2010, within one month, sb.'s illness took a favorable turn, is used in conjunction six months tumors and substantially disappears.Follow up a case by regular visits to stable disease so far.

(4) so-and-so is thanked, man, anti-Japanese hero.Within 2009, suffer from hemangioma, at local hospital western medical treatment 1 year, aggravation, then adopt the treatment of present composition powder, within one month, sb.'s illness took a favorable turn, and be used in conjunction two months month state of an illness and turn for the better by and large, month in and month out, canceration disappears substantially in rear after treatment one.

(5) grandson, female.Within 2008, find and suffer from cervical cancer late period, western medical treatment 1 year, aggravation, after use instead and adopt the treatment of present composition decoction, within one month, the state of an illness is clearly better, and be used in conjunction two months, symptom disappears substantially.Follow up a case by regular visits to so far not repeatedly.

Specific embodiment

Embodiment one

The preparation of decoction

Prescription: Moringa root 15 grams, leaf of Moringa 20 grams, Radix Salviae simplicifoliae 9 grams, Fel Ursi powder 3 grams, Semen Armeniacae Amarum 2 grams, Herba Scutellariae Barbatae 10 grams, Radix Paeoniae Rubra 12 grams, three spirits 9 grams, Rhizoma Curcumae 11 grams, 15 grams, Radix Notoginseng, Radix Ranunculi Ternati 8 grams, 20 grams, Radix Glycyrrhizae, Herba Dendrobii 17 grams.

Preparation method: recipe quantity medical material of weighing is placed in frying pan, add 1.5 the lucid yang sending up water, intense fire is boiled, and changes slow fire into and continues decoction 30 minutes, cooling, elimination medicinal residues.

Usage: every day sooner or later respectively once, drinks 200-300ml respectively depending on state of an illness weight at every turn, drinks after meal.

Embodiment two

The preparation of powder

Prescription: Moringa root 30 grams, leaf of Moringa 40 grams, Radix Salviae simplicifoliae 18 grams, Fel Ursi powder 6 grams, Semen Armeniacae Amarum 4 grams, Herba Scutellariae Barbatae 20 grams, Radix Paeoniae Rubra 24 grams, three spirits 18 grams, Rhizoma Curcumae 22 grams, 30 grams, Radix Notoginseng, Radix Ranunculi Ternati 16 grams, 40 grams, Radix Glycyrrhizae, Herba Dendrobii 34 grams.

Preparation method: get recipe quantity medical material of weighing, mixing, pulverizing, cross 100 mesh sieves, sterilization packaging, and every preparation unit is containing 10 grams of powders.Every day 4 times, each 10 grams, point early, middle and late, night takes.

Taboo: anemia of pregnant woman and deficiency and coldness body constitution patient forbidding.

Claims (3)

1. treat a compositions for kinds cancer, its feature is made up of following medical material: Moringa root, leaf of Moringa, wild loyal heart, Fel Ursi powder, Semen Armeniacae Amarum, Herba Scutellariae Barbatae, Radix Paeoniae Rubra, three spirits, Rhizoma Curcumae, Radix Notoginseng, Radix Ranunculi Ternati, Radix Glycyrrhizae, Herba Dendrobii.

2. treat the compositions of kinds cancer as claimed in claim 1, its each Parts by Ingredients proportioning is: Moringa root 15 parts, leaf of Moringa 20 parts, Radix Salviae simplicifoliae 9 parts, Fel Ursi powder 3 parts, Semen Armeniacae Amarum 2 parts, Herba Scutellariae Barbatae 10 parts, Radix Paeoniae Rubra 12 parts, three spirits 9 parts, Rhizoma Curcumae 11 parts, 15 parts, Radix Notoginseng, Radix Ranunculi Ternati 8 parts, 20 parts, Radix Glycyrrhizae, Herba Dendrobii 17 parts.

3. compositions as described in claim 1,2, for intestinal cancer, hepatocarcinoma, uterus carcinoma, osteocarcinoma, the brain cancer, gastric cancer, esophageal carcinoma, angiomatous treatment.