CN104893935A - Abalone and sea cucumber compound wine with effect of delaying senescence - Google Patents

Abalone and sea cucumber compound wine with effect of delaying senescence Download PDF

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CN104893935A
CN104893935A CN201510371236.0A CN201510371236A CN104893935A CN 104893935 A CN104893935 A CN 104893935A CN 201510371236 A CN201510371236 A CN 201510371236A CN 104893935 A CN104893935 A CN 104893935A
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abalone
sea cucumber
sea
herbal medicine
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徐伦超
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Great Marine Health Food Co Ltd In Qingdao
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Great Marine Health Food Co Ltd In Qingdao
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    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)

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Abstract

The invention discloses abalone and sea cucumber compound wine with an effect of delaying senescence. The abalone and sea cucumber compound wine with the effect of delaying senescence comprises abalone, sea cucumbers and Chinese herbal medicine raw materials which are compatible scientifically, preferably comprises the following raw materials in part by weight: 20-30 parts of sea cucumbers, 20-30 parts of abalone, 5-10 parts of radix astragali, 5-10 parts of wolfberries, 2-5 parts of ginseng, 10-15 parts of rhodiola rosea, 3-5 parts of dandelion, 3-5 parts of sea-buckthorn, 2-3 parts of polygonum multiflorum, 3-5 parts of cordyceps sinensis and 3-5 parts of stevia rebaudiana, and is technologically prepared by the following procedures of enzymolysis, extraction, mixing, blending, filling and sterilizing. The abalone and sea cucumber compound wine has the advantages that by a synergistic effect of the abalone, the sea cucumber and the Chinese herbal medicines, and the abalone and sea cucumber compound wine has obvious effects of resisting ageing, tonifying qi, strengthening and consolidating body resistance, resisting fatigue and prolonging life, is safe, does not have side effects, is convenient to drink and has a good market application prospect.

Description

A kind of Bao ginseng compound assembled alcoholic drinks with function of delaying senility
Technical field
The present invention relates to a kind of Bao ginseng compound assembled alcoholic drinks with function of delaying senility, particularly a kind of Bao ginseng compound assembled alcoholic drinks made for raw material with abalone, sea cucumber and vegetable Chinese herbal medicine, belongs to field of health care food.
Background technology
Abalone, ancient claims abalone, have another name called minute surface fish, nine hole spiral shells, improving eyesight fish, by army cap, be a kind of extra large mollush, belonging to the raw shellfish in monoshell sea of Gastropoda Bao Ke, is also the famous and precious food materials of Chinese tradition, ancient title abalone, the one in all kinds of delicacies, have the saying of " a bite abalone a bite gold "." Shiliao Bencao " is recorded, and abalone enters liver and leads to the stasis of blood, enters intestines and washs dirt, do not hinder vigour.Establishing-Yang, raw hundred arteries and veins, cure mainly the hot superinverse of liver, have a dizzy spell, hectic fever due to yin labor heat, blue or green the region between the heart and the diaphragm cataract or glaucoma, hypertension, the diseases such as retinal hemorrhage; Modern study result shows, the nutritive value of abalone is very abundant, containing 20 multiple amino acids, every hectogram Fresh abalone flesh of fish contains abundant protein 23.4 grams, 3.4 grams, fat, inorganic salt calcium 32 milligrams, 3.0 milligrams of iron, also have the iodine of a great deal of, zinc, phosphorus and vitamin A, B 1deng, often eat the yin-nourishing of abalone energy, flat liver, reinforce the kidney, adjustable acth secretion, regulate blood pressure, moisturize sharp intestines, control menoxenia, the illness such as constipation.
Sea cucumber is a kind of important marine invertebrate, fine and tender taste, nutritious, typical high protein, low-fat food, there is high nutritive value and pharmaceutical use, dietotherapy good merchantable brand for the patients such as hypertension, coronary heart disease, hepatitis and the elderly, it both can the immunizing power of enhancing body and hemopoietic function, can suppress again the growth and transfer etc. of multiple mould and human cancer cell.Before more than 1,000 years, just there is the custom of beche-de-mer in China, and sea cucumber is considered as a kind of invigorant of preciousness, is classified as first of " extra large eight delicacies ".In " new compilation of materia medica ", record sea cucumber has the effect of " sweet, salty, warm, tonifying kidney and benefiting sperm, establishing-Yang treatment impotence ", record in Qing Dynasty's supplementary Amplifications of the Compendium of Materia Medica " sea cucumber benefit warm in nature, sufficient enemy joins therefore named sea cucumber; Sweet-salty, kidney tonifying warp, beneficial marrow, dissolving phlegm prolong, take the photograph urine, establishing-Yang treats impotence, kills sore worm ".
Current abalone, sea cucumber are favored by consumers in general deeply as precious marine product, and edible way is mainly based on instant and dry products, and there is certain drawback, one is that tonic is single, or based on abalone, or based on sea cucumber; Two is a large amount of nutrient loss in cooking process, affects effect; Three is inconvenient eating.Therefore, the exploitation of abalone, sea cucumber nutritional health product can give full play to abalone, the food effect of sea cucumber, pharmacodynamic feature, is convenient to again human consumer and eats, comply with the market requirement, have good market outlook.
Aging is that each organ of body engenders the progressive process that hypofunction and reserve capabillity decline along with the continuous increase at age, and with advancing age, the same miopragia of various organs of human body, produces various pathology, little by little enters ageing state.Therefore prevent and delay senility to become current social medical research focus.Chinese herbal medicine resource is the rarity of Chinese traditional culture, because of its effect significantly, green, safely, have no side effect, the application in field of health care food is further extensive.Traditional Chinese medicine is thought: the major cause of human senility is deficient five internal organs, disorder of vital energy and blood etc., and by nourishing the five internal organs, QI and blood regulating is the important means that the traditional Chinese medical science delays senility.Chinese medicine has the advantage of rich experience and uniqueness in the research in anti-ageing.。Along with the continuous enhancing of people's prevention and health care consciousness, society increases day by day to the demand with function of delaying senility protective foods.Result of study shows, the healthcare products utilizing herbal medicine to develop contain abundant nutritive ingredient, be rich in the trace element such as polysaccharide, flavones, amino acid, potassium calcium, VITAMIN isoreactivity nutritive ingredient, there is adjustment function of human body, strengthening immunity, nourishing and fit keeping function, the effect such as to promote longevity.
At present, also there is more drawback in the application of herbal medicine in field of health care food, is difficult to the health-care effect really playing herbal medicine.The present invention is directed to the problems referred to above, develop a kind of Bao ginseng compound assembled alcoholic drinks with function of delaying senility utilizing abalone, sea cucumber and composite Chinese herbal, meet the demand of market to sea cucumber and herbal health care food.
Summary of the invention
For overcoming the deficiencies in the prior art, the object of the present invention is to provide a kind of Bao ginseng compound assembled alcoholic drinks with function of delaying senility, this Bao ginseng compound assembled alcoholic drinks has anti-ageing, tonifying Qi help, strengthens the body resistance to consolidate the constitution, antifatigue, the effect such as to promote longevity.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The invention provides a kind of Bao ginseng compound assembled alcoholic drinks with function of delaying senility, it is characterized in that Bao ginseng compound assembled alcoholic drinks raw material composition and quality proportioning are: sea cucumber 20 ~ 30 parts, abalone 20 ~ 30 parts, the Radix Astragali 5 ~ 10 parts, matrimony vine 5 ~ 10 parts, ginseng 2 ~ 5 parts, Root of Kirilow Rhodiola 10 ~ 15 parts, taraxacum 3 ~ 5 parts, sea-buckthorn 3 ~ 5 parts, Tuber Fleeceflower Root 2 ~ 3 parts, Cordyceps sinensis 3 ~ 5 parts, sweet Stevia 3 ~ 5 parts.
The preferred technical solution of the present invention is: a kind of Bao ginseng compound assembled alcoholic drinks with function of delaying senility, is characterized in that: it is characterized in that Bao ginseng compound assembled alcoholic drinks raw material composition and quality proportioning are: sea cucumber 25 parts, abalone 25 parts, the Radix Astragali 8 parts, matrimony vine 7 parts, ginseng 4 parts, Root of Kirilow Rhodiola 12 parts, taraxacum 4 parts, sea-buckthorn 4 parts, Tuber Fleeceflower Root 2.5 parts, Cordyceps sinensis 4 parts, sweet Stevia 4 parts.
The invention provides a kind of Bao ginseng compound assembled alcoholic drinks with function of delaying senility, it is characterized in that being prepared by following steps:
(1) abalone, sea cucumber preprocessing: adopt pollution-free, grow normal, healthy abalone, sea cucumber, remove silt and dirt settling thereof with water that is clean, flowing, pulverize with tissue mashing machine;
(2) enzymolysis: abalone, sea cucumber are mixed in proportion, adds the pure water of matter 5 times of mass ratioes, adds the neutral protease of mass percent 3 ~ 5%, mixes, enzymolysis 2 ~ 3h under 50 ~ 60 DEG C of conditions;
(3) deactivation: enzymolysis post-heating boils, maintains 15 ~ 20min by enzyme-deactivating, obtains Bao ginseng enzymolysis solution;
(4) herbal medicine pre-treatment: be mixed in proportion by herbal raw material, crosses 200 mesh sieves after pulverizing;
(5) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 5 times, hot digestion 30 ~ 60min;
(6) filter: filter, obtain Chinese herbal medicine leaching liquor;
(7) mix: Bao is joined enzymolysis solution and Chinese herbal medicine leaching liquor mixing;
(8) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging, obtains clarification fricassee sea cucumbers with abalone complex liquid;
(9) allocate: allocate with edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(10) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(11) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining fricassee sea cucumbers with abalone compound assembled alcoholic drinks.
The invention provides a kind of Bao ginseng compound assembled alcoholic drinks with function of delaying senility, carried out toxicology test and the safety evaluation of Bao ginseng compound assembled alcoholic drinks by animal experiment.Chmice acute Oral toxicity test-results shows, this Bao ginseng compound assembled alcoholic drinks is greater than high dose group 75mg/kgbw to chmice acute per os maximum tolerated dose; Genetic toxicity test mouse marrow cell micro nuclear test and mouse inbred strain two test-results are feminine gender, show that this Bao ginseng compound assembled alcoholic drinks is without mutagenesis; From rat 30d feeding study, the behavior of rat sign is normal, figure is healthy, blood and blood parameters also change without exception, and therefore the dosage (150 times of human body recommended amounts) of 75mg/kgbw belongs to safe dose; Genetic toxicity test and rat 30d feeding study result are feminine gender, and therefore determine that this Bao ginseng compound assembled alcoholic drinks belongs to non-toxic type food, people can be safe relieved edible.
The invention provides a kind of Bao ginseng compound assembled alcoholic drinks with function of delaying senility, it is advantageous that scientific compatibility abalone, sea cucumber and multiple herbal medicine, by the synergy between sea cucumber and herbal medicine can effectively anti-ageing, tonifying Qi help, strengthen the body resistance to consolidate the constitution, antifatigue, the effect such as to promote longevity, safety has no side effect, instant.Different herbal medicine nature and flavor are different, effect also exists huge difference, complicated interaction relationship is there is after different herbal medicine combinations, and proportioning between herbal medicine is closer, different ratio also will make monarch relation that substantial change occurs, thus make the relation generation material alterations of composite Chinese herbal.The application passes through abalone, sea cucumber and the Radix Astragali, matrimony vine, ginseng, Root of Kirilow Rhodiola, taraxacum, sea-buckthorn, Tuber Fleeceflower Root, Cordyceps sinensis, there is complicated interaction relationship to each other in the herbal medicine such as sweet Stevia, rational proportion, achieve unforeseeable technique effect, Bao is made to join the relation generation material alterations of compound assembled alcoholic drinks, adopt RNA isolation kit determination experiment mice skin tissue superoxide-dismutase (SOD), Selenoperoxidase (GSH-Px), the indexs such as mda (MDA) and oxyproline (Hyp), result shows SOD, GSH-Px, the indexs such as Hyp are significantly higher than blank group (P<0.01), MDA is significantly lower than blank group (P<0.01), illustrate that product has the activity that delays senility preferably, and test-results shows to change the anti-ageing ability (P<0.01) that Bao ginseng compound assembled alcoholic drinks raw material composition or proportioning can reduce Bao ginseng compound assembled alcoholic drinks, abalone is described, synergy between sea cucumber and herbal medicine serves and significantly promote the effect that Bao joins compound assembled alcoholic drinks functionally active.
Embodiment
below in conjunction with embodiment, the present invention will be further described.
embodiment 1:
There is a Bao ginseng compound assembled alcoholic drinks for function of delaying senility, prepared by following steps:
(1) abalone, sea cucumber preprocessing: adopt pollution-free, grow normal, healthy abalone, sea cucumber, remove silt and dirt settling thereof with water that is clean, flowing, pulverize with tissue mashing machine;
(2) enzymolysis: by abalone, sea cucumber in sea cucumber 20 parts, abalone 30 parts of ratio mixing, add the pure water of matter 5 times of mass ratioes, add the neutral protease of mass percent 3%, mix, enzymolysis 3h under 50 ~ 60 DEG C of conditions;
(3) deactivation: enzymolysis post-heating boils, maintains 15 ~ 20min by enzyme-deactivating, obtains Bao ginseng enzymolysis solution;
(4) herbal medicine pre-treatment: by herbal raw material in the Radix Astragali 5 parts, matrimony vine 10 parts, ginseng 2 parts, Root of Kirilow Rhodiola 15 parts, taraxacum 3 parts, sea-buckthorn 5 parts, Tuber Fleeceflower Root 2 parts, Cordyceps sinensis 5 parts, sweet Stevia 3 parts of ratio mixing, cross 200 mesh sieves after pulverizing;
(5) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 5 times, hot digestion 30 ~ 60min;
(6) filter: filter, obtain Chinese herbal medicine leaching liquor;
(7) mix: Bao is joined enzymolysis solution and Chinese herbal medicine leaching liquor mixing;
(8) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging, obtains clarification fricassee sea cucumbers with abalone complex liquid;
(9) allocate: allocate with edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(10) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(11) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining fricassee sea cucumbers with abalone compound assembled alcoholic drinks.
embodiment 2:
There is a Bao ginseng compound assembled alcoholic drinks for function of delaying senility, prepared by following steps:
(1) abalone, sea cucumber preprocessing: adopt pollution-free, grow normal, healthy abalone, sea cucumber, remove silt and dirt settling thereof with water that is clean, flowing, pulverize with tissue mashing machine;
(2) enzymolysis: by abalone, sea cucumber in sea cucumber 25 parts, abalone 25 parts of ratio mixing, add the pure water of matter 5 times of mass ratioes, add the neutral protease of mass percent 4%, mix, enzymolysis 2.5h under 50 ~ 60 DEG C of conditions;
(3) deactivation: enzymolysis post-heating boils, maintains 15 ~ 20min by enzyme-deactivating, obtains Bao ginseng enzymolysis solution;
(4) herbal medicine pre-treatment: by herbal raw material in the Radix Astragali 8 parts, matrimony vine 7 parts, ginseng 4 parts, Root of Kirilow Rhodiola 12 parts, taraxacum 4 parts, sea-buckthorn 4 parts, Tuber Fleeceflower Root 2.5 parts, Cordyceps sinensis 4 parts, sweet Stevia 4 parts of ratio mixing, cross 200 mesh sieves after pulverizing;
(5) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 5 times, hot digestion 30 ~ 60min;
(6) filter: filter, obtain Chinese herbal medicine leaching liquor;
(7) mix: Bao is joined enzymolysis solution and Chinese herbal medicine leaching liquor mixing;
(8) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging, obtains clarification fricassee sea cucumbers with abalone complex liquid;
(9) allocate: allocate with edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(10) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(11) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining fricassee sea cucumbers with abalone compound assembled alcoholic drinks.
embodiment 3:
There is a Bao ginseng compound assembled alcoholic drinks for function of delaying senility, prepared by following steps:
(1) abalone, sea cucumber preprocessing: adopt pollution-free, grow normal, healthy abalone, sea cucumber, remove silt and dirt settling thereof with water that is clean, flowing, pulverize with tissue mashing machine;
(2) enzymolysis: by abalone, sea cucumber in sea cucumber 30 parts, abalone 20 parts of ratio mixing, add the pure water of matter 5 times of mass ratioes, add the neutral protease of mass percent 5%, mix, enzymolysis 2h under 50 ~ 60 DEG C of conditions;
(3) deactivation: enzymolysis post-heating boils, maintains 15 ~ 20min by enzyme-deactivating, obtains Bao ginseng enzymolysis solution;
(4) herbal medicine pre-treatment: by herbal raw material in the Radix Astragali 10 parts, matrimony vine 5 parts, ginseng 5 parts, Root of Kirilow Rhodiola 10 parts, taraxacum 5 parts, sea-buckthorn 3 parts, Tuber Fleeceflower Root 3 parts, Cordyceps sinensis 3 parts, sweet Stevia 5 parts of ratio mixing, cross 200 mesh sieves after pulverizing;
(5) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 5 times, hot digestion 30 ~ 60min;
(6) filter: filter, obtain Chinese herbal medicine leaching liquor;
(7) mix: Bao is joined enzymolysis solution and Chinese herbal medicine leaching liquor mixing;
(8) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging, obtains clarification fricassee sea cucumbers with abalone complex liquid;
(9) allocate: allocate with edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(10) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(11) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining fricassee sea cucumbers with abalone compound assembled alcoholic drinks.
Above embodiment only for illustration of technical scheme of the present invention, but not is limited; Although be described in detail by invention with reference to previous embodiment, for the person of ordinary skill of the art, still the technical scheme described in previous embodiment can be modified, or equivalent replacement has been carried out to wherein portion of techniques feature; And to these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.

Claims (1)

1. there is a Bao ginseng compound assembled alcoholic drinks for function of delaying senility, it is characterized in that being prepared by following steps:
(1) abalone, sea cucumber preprocessing: adopt pollution-free, grow normal, healthy abalone, sea cucumber, remove silt and dirt settling thereof with water that is clean, flowing, pulverize with tissue mashing machine;
(2) enzymolysis: by abalone, sea cucumber in sea cucumber 20 ~ 30 parts, abalone 20 ~ 30 parts of ratio mixing, add the pure water of matter 5 times of mass ratioes, add the neutral protease of mass percent 3 ~ 5%, mix, enzymolysis 2 ~ 3h under 50 ~ 60 DEG C of conditions;
(3) deactivation: enzymolysis post-heating boils, maintains 15 ~ 20min by enzyme-deactivating, obtains Bao ginseng enzymolysis solution;
(4) herbal medicine pre-treatment: by herbal raw material in the Radix Astragali 5 ~ 10 parts, matrimony vine 5 ~ 10 parts, ginseng 2 ~ 5 parts, Root of Kirilow Rhodiola 10 ~ 15 parts, taraxacum 3 ~ 5 parts, sea-buckthorn 3 ~ 5 parts, Tuber Fleeceflower Root 2 ~ 3 parts, Cordyceps sinensis 3 ~ 5 parts, sweet Stevia 3 ~ 5 parts of ratio mixing, cross 200 mesh sieves after pulverizing;
(5) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 5 times, hot digestion 30 ~ 60min;
(6) filter: filter, obtain Chinese herbal medicine leaching liquor;
(7) mix: Bao is joined enzymolysis solution and Chinese herbal medicine leaching liquor mixing;
(8) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging, obtains clarification fricassee sea cucumbers with abalone complex liquid;
(9) allocate: allocate with edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(10) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(11) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining fricassee sea cucumbers with abalone compound assembled alcoholic drinks.
CN201510371236.0A 2015-06-30 2015-06-30 Abalone and sea cucumber compound wine with effect of delaying senescence Pending CN104893935A (en)

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CN115844023A (en) * 2022-12-29 2023-03-28 江西沐恩堂生物科技有限公司 Sea cucumber peptidase sea buckthorn powder and preparation method thereof

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