CN104857320A - Anti-fatigue health-care food and preparation method thereof and application - Google Patents
Anti-fatigue health-care food and preparation method thereof and application Download PDFInfo
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- CN104857320A CN104857320A CN201510220847.5A CN201510220847A CN104857320A CN 104857320 A CN104857320 A CN 104857320A CN 201510220847 A CN201510220847 A CN 201510220847A CN 104857320 A CN104857320 A CN 104857320A
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Abstract
The invention discloses a health-care food with effect of anti-fatigue. The health-care food includes Japanese peristrophe herb, lung channel herb, rehmannia, rehmannia and so on; the dosage form is tablet, capsule or granula. The invention further discloses a preparation method and an application in preparing the anti-fatigue health-care food.
Description
Technical field
The present invention relates to technical field of medicine, be specifically related to health food of a kind of resisting fatigue and its preparation method and application.
Background technology
Fatigue be health overworked, for a long time nervous, sleep insuffience time normal and important reaction.But it also can be the non-specific performance of a kind of psychology or physiological barrier, especially virus or bacterial hormonal system, cardiovascular system or nervous system infection disease.Due to too fast consumption, damage repair mechanism, hormone produces not enough, or not enough cellular energy and the nutrient substance required for growth of all causing of nutrition intake lacks, the therefore tired situation reflecting hypermetabolism and metabolism attenuating.Up to now, people are finding a kind of health food of resisting fatigue making simple, taking convenience, have no side effect always.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of health food of resisting fatigue.
Technical scheme: the object of the invention is by following scheme realize:
Have a health food for anti-fatigue effect, it is prepared by the raw material of following parts by weight: Herba Peristrophes 20-30 part, sanicula lamelligera Hance 30-40 part, Radix Rehmanniae 15-25 part, Rhizoma Gastrodiae 30-40 part, Radix Paeoniae Alba 20-30 part, Flos Chrysanthemi 20-30 part, Fructus Lycii 30-40 part, Concha Haliotidis 15-25 part, Concha Margaritifera 30-40 part, Radix Astragali 20-30 part, Rhizoma Cimicifugae 20-30 part, Semen Ziziphi Spinosae 30-40 part, Fructus Corni 15-25 part, Fructus Ligustri Lucidi 30-40 part, Herba Ecliptae 20-30 part and Radix Glycyrrhizae 10-30 part.
Described a kind of health food with anti-fatigue effect, it is prepared by the raw material of following parts by weight: Herba Peristrophes 25 parts, sanicula lamelligera Hance 35 parts, Radix Rehmanniae 20 parts, 35 parts, Rhizoma Gastrodiae, the Radix Paeoniae Alba 25 parts, Flos Chrysanthemi 25 parts, Fructus Lycii 35 parts, Concha Haliotidis 20 parts, Concha Margaritifera 35 parts, the Radix Astragali 25 parts, Rhizoma Cimicifugae 25 parts, Semen Ziziphi Spinosae 35 parts, Fructus Corni 20 parts, Fructus Ligustri Lucidi 35 parts, Herba Ecliptae 25 parts and 20 parts, Radix Glycyrrhizae.
The described health food with anti-fatigue effect, preparation method is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The application had in anti-fatigue effect health food prepared by the described health food with anti-fatigue effect.
Herba Peristrophes, Classification system: Peristrophe japonica (Thunb.) Bremek., Acanthaceae, Premna microphylla Turez belongs to herbaceous plant, up to 50 centimetres.Leaf egg shape square is circular, and poly-umbrella flower top life or axil are born in top axil, and filigree is elongated, and flower pesticide is by long bristle, and capsule dredges raw pubescence, and during cracking, placenta is not upspring, and seed has little verruca.Be distributed in various places on the south basin, farm labourer river.Be born in the dark and damp places such as hillside, sylvan life, roadside, small stream limit.Pungent, the micro-hardship of nature and flavor, cool.Relieving the exterior syndrome by diaphoresis, heat-clearing and toxic substances removing, spasmolytic.For flu, laryngopharynx swelling and pain, diphtheria, infantile dyspepsia, infantile hyperpyrexia, carbuncle furuncle and phyma poison, venom.The present invention is with all herbal medicine.Sanicula lamelligera Hance is Umbelliferae sanicle platymiscium sanicula lamelligera Hance Sanicula lamelligera Hance, with all herbal medicine, and cold expelling cough-relieving, promoting the circulation of blood dysmenorrhea.For cough due to wind and cold, pertussis, menoxenia, amenorrhea, lumbago.All the other are pharmacopeia kind.
Beneficial effect:
From theory of Chinese medical science, in we, Herba Peristrophes, sanicula lamelligera Hance, Radix Rehmanniae, Rhizoma Gastrodiae, the Radix Paeoniae Alba are monarch drug, heat-clearing and toxic substances removing, benefiting QI for activating blood circulation, Flos Chrysanthemi, Fructus Lycii, Concha Haliotidis, Concha Margaritifera, the Radix Astragali, Rhizoma Cimicifugae, Semen Ziziphi Spinosae, Fructus Corni, Fructus Ligustri Lucidi, Herba Ecliptae are ministerial drug, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, plays heat-clearing and toxic substances removing, QI invigorating, the effect of invigorating blood circulation altogether, for alleviating physical fatigue.Formulation of the present invention is reasonable, and compatibility is rigorous.Consist of Chinese crude drug, have no side effect, low price.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, embodiment 1 is prepared
Get Herba Peristrophes 25g, sanicula lamelligera Hance 35g, Radix Rehmanniae 20g, Rhizoma Gastrodiae 35g, Radix Paeoniae Alba 25g, Flos Chrysanthemi 25g, Fructus Lycii 35g, Concha Haliotidis 20g, Concha Margaritifera 35g, Radix Astragali 25g, Rhizoma Cimicifugae 25g, Semen Ziziphi Spinosae 35g, Fructus Corni 20g, Fructus Ligustri Lucidi 35g, Herba Ecliptae 25g and Radix Glycyrrhizae 20g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, make granule.Also tablet or capsule can be conventionally prepared into.
2, the pharmacodynamic study of resisting fatigue
Laboratory animal: Kunming mouse, male, body weight 18-22g, Shanghai Slac Experimental Animal Co., Ltd. provides, production licence: SCXK (Shanghai) 2007-0005.
Experimental agents: prepare by the preparation method of above-described embodiment 1, specification is 10g crude drug/bag.
Positive drug Radix Panacis Quinquefolii buccal tablets, Xiamen good fortune has come health food company limited, the strong word G20040446 of state's food, lot number: 20140513.Specification: every dress 1.25g.Patient uses generally each 2, every day 2 times, i.e. people's consumption per day 5g, and being equivalent to every 20g mice consumption is 5*0.0026=0.013g, and calculate by per kilogram mice, namely positive drug group gives Radix Panacis Quinquefolii buccal tablets 0.65g/kg.
Experimentation: select healthy mice 50, separate 10 at random as normal group, all the other 40 mices, be divided into 4 groups at random: high dose group, middle dosage group, low dose group, positive drug Radix Panacis Quinquefolii buccal tablets group, wherein 3 dosage component Gei 0.8, 0.4, the health food of 0.2g, Radix Panacis Quinquefolii buccal tablets group is by above-mentioned dosage gastric infusion, normal group is to the water of 0.2ml, every morning 1 time, continuous 30d, carry out mice burden swimming test, mouse tail bears the sheet lead of Mouse Weight 5%, putting into water temperature is 25 DEG C, in the swimming trunk of depth of water 35cm, the dead time is exhausted from swimming to power with stopwatch record, each group of data represent with means standard deviation, t test is carried out between group.The results are shown in Table 1
The impact (n=10) that this health food of table 1. is tested mice burden swimming
Note: compare * p<0.05**<0.01 with normal group, compares with positive drug group
#p<0.05
Conclusion: this health food compares with normal group, obviously extends the mice burden swimming time, illustrates that the present invention has antifatigue effect, compare with positive drug, time lengthening, illustrate that resisting fatigue effect of the present invention is better than positive drug.
Claims (4)
1. one kind has the health food of anti-fatigue effect, it is characterized in that, it is prepared by the raw material of following parts by weight: Herba Peristrophes 20-30 part, sanicula lamelligera Hance 30-40 part, Radix Rehmanniae 15-25 part, Rhizoma Gastrodiae 30-40 part, Radix Paeoniae Alba 20-30 part, Flos Chrysanthemi 20-30 part, Fructus Lycii 30-40 part, Concha Haliotidis 15-25 part, Concha Margaritifera 30-40 part, Radix Astragali 20-30 part, Rhizoma Cimicifugae 20-30 part, Semen Ziziphi Spinosae 30-40 part, Fructus Corni 15-25 part, Fructus Ligustri Lucidi 30-40 part, Herba Ecliptae 20-30 part and Radix Glycyrrhizae 10-30 part.
2. a kind of health food with anti-fatigue effect as claimed in claim 1, it is characterized in that, it is prepared by the raw material of following parts by weight: Herba Peristrophes 25 parts, sanicula lamelligera Hance 35 parts, Radix Rehmanniae 20 parts, 35 parts, Rhizoma Gastrodiae, the Radix Paeoniae Alba 25 parts, Flos Chrysanthemi 25 parts, Fructus Lycii 35 parts, Concha Haliotidis 20 parts, Concha Margaritifera 35 parts, the Radix Astragali 25 parts, Rhizoma Cimicifugae 25 parts, Semen Ziziphi Spinosae 35 parts, Fructus Corni 20 parts, Fructus Ligustri Lucidi 35 parts, Herba Ecliptae 25 parts and 20 parts, Radix Glycyrrhizae.
3. there is the health food of anti-fatigue effect as claimed in claim 1, it is characterized in that, preparation method is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. the application had in anti-fatigue effect health food prepared by the health food as claimed in claim 1 with anti-fatigue effect.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510220847.5A CN104857320A (en) | 2015-05-05 | 2015-05-05 | Anti-fatigue health-care food and preparation method thereof and application |
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| CN201510220847.5A CN104857320A (en) | 2015-05-05 | 2015-05-05 | Anti-fatigue health-care food and preparation method thereof and application |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101850030A (en) * | 2010-06-02 | 2010-10-06 | 烟台大洋制药有限公司 | Anti-fatigue medicament or health food |
| CN102961584A (en) * | 2012-12-08 | 2013-03-13 | 南京正宽医药科技有限公司 | Traditional Chinese medicine composition capable of relieving fatigue, as well as preparation method and application thereof |
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2015
- 2015-05-05 CN CN201510220847.5A patent/CN104857320A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101850030A (en) * | 2010-06-02 | 2010-10-06 | 烟台大洋制药有限公司 | Anti-fatigue medicament or health food |
| CN102961584A (en) * | 2012-12-08 | 2013-03-13 | 南京正宽医药科技有限公司 | Traditional Chinese medicine composition capable of relieving fatigue, as well as preparation method and application thereof |
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Application publication date: 20150826 |