CN104840824A - Medicine preparation for treating cervicitis - Google Patents
Medicine preparation for treating cervicitis Download PDFInfo
- Publication number
- CN104840824A CN104840824A CN201510293943.2A CN201510293943A CN104840824A CN 104840824 A CN104840824 A CN 104840824A CN 201510293943 A CN201510293943 A CN 201510293943A CN 104840824 A CN104840824 A CN 104840824A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- cervicitis
- treatment
- medicine preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention belongs to the field of medicines, and provides a medicine preparation for treating cervicitis. The medicine preparation is prepared from the following raw materials: 20 parts of pleomele cambodiana, 18 parts of methyl methionine, 15 parts of fruit of thin leaf buckthorn roots, 16 parts of rhizome of large leaf curculigo, 20 parts of tulip, 25 parts of hovenia acerba roots, 17 parts of gentianopsis barbata, 20 parts of coix lacryma-jobi, 12 parts of stems and leaves of hedge glorybind, 16 parts of campylotropis macrocarpa and 18 parts of roots of soulie barberry. The medicine preparation can be used for treating cervicitis.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of pharmaceutical preparation being used for the treatment of cervicitis and its preparation method and application.
Background technology
Cervicitis is one of gynecological's common disease, comprises vaginal part of cervix inflammation and cervical canal mucosal inflammation.Because cervical canal portio vaginalis squamous epithelial cancer continues mutually with vagina squamous, colpitis all can cause vaginal part of cervix inflammation.Because cervical canal mucosal epithelium is simple columnar epithelium, anti-infection ability is poor, easily infects.Clinical common cervicitis is Semen Impatientis cervical canal mucositis, if acute cervicitis is without timely diagnosis and treatment or pathogen sustainable existence, can cause chronic cervicitis disease.Because sickness rate is high, for this reason, be bursting to and develop the needs that more medicines for the treatment of cervicitis safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of cervicitis disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of pharmaceutical preparation being used for the treatment of cervicitis, the active component contained by it is extracted by following weight crude drug and is prepared from: Folium Dracaenae Cambnodianae 20 parts, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 18 parts, Radix rhamni leptophyllae 15 parts, Rhizoma Curculiginis Capitulatae 16 parts, Flos Tulipae Gesnerianae 20 parts, Radix Hoveniae 25 parts, Herba Gentianopsis Paludosae 17 parts, Radix Coicis 20 parts, Caulis et Folium Calystegiae sepii 12 parts, Radix Campylotropis Macrocarpae 16 parts, Radix Berberidis soulieanae 18 parts.
The described pharmaceutical preparation being used for the treatment of cervicitis, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described pharmaceutical preparation being used for the treatment of cervicitis, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make granule, tablet, capsule.
The described application of pharmaceutical preparation in preparation treatment cervicitis medicine being used for the treatment of cervicitis.
Folium Dracaenae Cambnodianae is the leaf of Agavaceae plant mountain Cycas revoluta.Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) is the root of Buxaceae plant open country fan flower.Radix rhamni leptophyllae is the root of Rhamnaceae plant fineflower buckthorn.Rhizoma Curculiginis Capitulatae is the rhizome of amrallid great Ye Rhizoma Curculiginis.Flos Tulipae Gesnerianae is the flower of liliaceous plant Flos Tulipae Gesnerianae.Radix Hoveniae is the root of Rhamnaceae plant Semen Hoveniae (Fructus Hoveniae).Herba Gentianopsis Paludosae is the herb of gentianaceae plant China Herba Gentianopsis Paludosae.Radix Coicis is the root of grass Semen Coicis.Caulis et Folium Calystegiae sepii is the stem and leaf of convolvulaceous plant bellbine.Radix Campylotropis Macrocarpae is the root of the leguminous plant Hang Zi tip.Radix Berberidis soulieanae is root and the peel of stem of the false porcupine quill of Berberidaceae plant.
Beneficial effect: heat-clearing and toxic substances removing of the present invention, blood circulation promoting and blood stasis dispelling, invigorating the spleen and replenishing QI, eliminating blood stasis to promote regeneration of blood, full side's treatment cervicitis successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Folium Dracaenae Cambnodianae 20g, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 18g, Radix rhamni leptophyllae 15g, Rhizoma Curculiginis Capitulatae 16g, Flos Tulipae Gesnerianae 20g, Radix Hoveniae 25g, Herba Gentianopsis Paludosae 17g, Radix Coicis 20g, Caulis et Folium Calystegiae sepii 12g, Radix Campylotropis Macrocarpae 16g, Radix Berberidis soulieanae 18g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Folium Dracaenae Cambnodianae 20g, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 18g, Radix rhamni leptophyllae 15g, Rhizoma Curculiginis Capitulatae 16g, Flos Tulipae Gesnerianae 20g, Radix Hoveniae 25g, Herba Gentianopsis Paludosae 17g, Radix Coicis 20g, Caulis et Folium Calystegiae sepii 12g, Radix Campylotropis Macrocarpae 16g, Radix Berberidis soulieanae 18g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Folium Dracaenae Cambnodianae 20g, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 18g, Radix rhamni leptophyllae 15g, Rhizoma Curculiginis Capitulatae 16g, Flos Tulipae Gesnerianae 20g, Radix Hoveniae 25g, Herba Gentianopsis Paludosae 17g, Radix Coicis 20g, Caulis et Folium Calystegiae sepii 12g, Radix Campylotropis Macrocarpae 16g, Radix Berberidis soulieanae 18g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, pharmaceutical preparation treatment cervicitis of the present invention clinical research
Case selection: as the medicine for the treatment of cervicitis, select the routine clinical observation of virus in patients with cervicitis 60 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 30 example, 28 ~ 45 years old age, 36.8 years old mean age, the course of disease 1 ~ 2 year; Matched group women 30 example, 22 ~ 53 years old age, 39.8 years old mean age, the course of disease 1 ~ 2 year; The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
Diagnostic criteria: (one) clinical manifestation 1. vaginal secretions increases, many in mucus purulence, or be mixed with blood.2. pruritus vulvae and burning sensation, caused by how per vaginam secretions stimulates.(2) auxiliary examination 1. secretions white blood cell detection: Gram's staining made by cervical canal purulent secretion smear, neutrophilic granulocyte >30/HPF; Or vaginal secretions humidity strip checks, leukocyte >10/HPF, and get rid of colpitis.2. cervix uteri is drawn materials pathogen detection: should do gonococcus and chlamydial detection, and with or without the detection of bacterial vaginosis and trichomonal vaginitis.(1) detection method that gonococcus is conventional: 1. secretions smear Gram's staining: search in neutrophilic granulocyte with or without gram-negative diplococcus; 2. gonococcus is cultivated: for diagnosing the goldstandard of gonorrhea; 3. detection of nucleic acids: comprise nucleic acid hybridization and nucleic acid amplification.(2) detection method that chlamydia trachomatis is conventional: 1. cell culture: be diagnosis meeting standard, because its method is complicated, clinical less application; 2. elisa: detecting Chlamydia antigen, is clinical common method; 3. detection of nucleic acids: comprise nucleic acid hybridization and nucleic acid amplification, especially the latter detects responsive, the special method of chlamydia infection.
Medicament selection: the preparation method that treatment group takes above-mentioned granule embodiment prepares medicine of the present invention, oral, every day 3 times, each 1 time sooner or later, each 10g, after meal warm water delivery service; Within 15 days, be 1 course for the treatment of, 2 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.Matched group takes moldin sheet, oral, every day 2 times, each 1 time sooner or later, each 2; Within 10 days, be 1 course for the treatment of, take 3 ~ 5 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Efficacy determination: (1) cures: with transference cures such as the bloods streak in leucorrhoea grow in quantity, purulence and leucorrhea, physical distress malaise symptoms disappears.(2) effective: to alleviate to some extent with symptoms such as the bloods streak in leucorrhoea grow in quantity, purulence and leucorrhea, physical distress malaise symptoms alleviates.(3) invalid: clinical symptoms is without obvious change.
Therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Cure | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 30 | 15 | 14 | 1 | 96.7 |
| Blank group | 30 | 1 | 2 | 27 | 10 |
Visible the present invention has good therapeutic effect to cervicitis, and toxic and side effects does not occur treatments period.
Claims (2)
1. one kind is used for the treatment of the pharmaceutical preparation of cervicitis, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Folium Dracaenae Cambnodianae 20 parts, Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) 18 parts, Radix rhamni leptophyllae 15 parts, Rhizoma Curculiginis Capitulatae 16 parts, Flos Tulipae Gesnerianae 20 parts, Radix Hoveniae 25 parts, Herba Gentianopsis Paludosae 17 parts, Radix Coicis 20 parts, Caulis et Folium Calystegiae sepii 12 parts, Radix Campylotropis Macrocarpae 16 parts, Radix Berberidis soulieanae 18 parts.
2. be used for the treatment of the application of pharmaceutical preparation in treatment cervicitis medicine of cervicitis according to claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510293943.2A CN104840824A (en) | 2015-06-01 | 2015-06-01 | Medicine preparation for treating cervicitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510293943.2A CN104840824A (en) | 2015-06-01 | 2015-06-01 | Medicine preparation for treating cervicitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104840824A true CN104840824A (en) | 2015-08-19 |
Family
ID=53841069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510293943.2A Pending CN104840824A (en) | 2015-06-01 | 2015-06-01 | Medicine preparation for treating cervicitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104840824A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080088834A (en) * | 2007-03-30 | 2008-10-06 | 강홍구 | Herbal composition for relieving and treating primary dysmenorrhea |
-
2015
- 2015-06-01 CN CN201510293943.2A patent/CN104840824A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080088834A (en) * | 2007-03-30 | 2008-10-06 | 강홍구 | Herbal composition for relieving and treating primary dysmenorrhea |
Non-Patent Citations (2)
| Title |
|---|
| 成都中医学院妇科教研室: "《中医妇科学》", 31 October 1986 * |
| 陆鹏飞等: "《陆氏中医诊治验方》", 30 April 2014 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101628108B (en) | Traditional Chinese medicinal granules for treating wind-cold evil and preparation method thereof | |
| CN103301271B (en) | Tibetan medicine for treating pharyngitis and preparation method thereof | |
| CN104840687A (en) | Pharmaceutical preparation for treating pelvic inflammation | |
| CN114903944B (en) | Composition and preparation for improving cervical HPV infection symptoms and preparation method | |
| CN104436150A (en) | Traditional Chinese medicine composition used for treating rhinitis | |
| CN104258236A (en) | Traditional Chinese medicine composition for nursing vaginas of women in puerperium | |
| CN104225472A (en) | Traditional Chinese medicine preparation for treating oral mucosa lesions as well as preparation method and application thereof | |
| CN104857096A (en) | Traditional Chinese medicine composition for treating cervicitis | |
| CN103341059A (en) | Chinese medicine composition for treating non-gonococcal urethritis | |
| CN104840824A (en) | Medicine preparation for treating cervicitis | |
| CN103301415B (en) | Medicinal composition for preventing and treating intrauterine adhesion after induced abortion operation and application thereof | |
| CN105055831A (en) | Traditional Chinese medicine for treating leukorrhagia of women and preparation method thereof | |
| CN104815151A (en) | Traditional Chinese medicine for treating warm-dryness lung injury type cough | |
| CN104337901A (en) | Chinese medicinal preparation for treating nonspecific cystitis and preparation method thereof | |
| CN1318061C (en) | Method for preparing medicine | |
| CN105055702A (en) | Pharmaceutical preparation for treating chronic pelvic inflammatory disease | |
| CN105106419A (en) | Medicinal preparation for treating pelvic inflammation | |
| CN105055786A (en) | Medicinal preparation for treating cough | |
| CN104800497A (en) | Traditional Chinese medicine composition for treating irregular menstruation of gynecology | |
| CN105267400A (en) | Medicine preparation for treating gynecological vaginitis | |
| CN105168397A (en) | Medicine composition for preventing and treating nephrosis | |
| CN104707124A (en) | Traditional Chinese medicine preparation for treating chronic endometritis | |
| CN114533778A (en) | Chitosan sophora flavescens medicament and preparation method and application thereof | |
| CN115590940A (en) | A vaginal medicated membrane for treating vaginal diseases and removing odor and fragrance, and its preparation method | |
| CN104257974A (en) | Traditional Chinese medicine for treating exuberant heat-toxicity type acute pelvic inflammatory disease |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| EXSB | Decision made by sipo to initiate substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150819 |
|
| RJ01 | Rejection of invention patent application after publication |