CN104740776B - Self energizing Ventricular resynchronization cardioverter defibrillators - Google Patents
Self energizing Ventricular resynchronization cardioverter defibrillators Download PDFInfo
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- CN104740776B CN104740776B CN201310733117.6A CN201310733117A CN104740776B CN 104740776 B CN104740776 B CN 104740776B CN 201310733117 A CN201310733117 A CN 201310733117A CN 104740776 B CN104740776 B CN 104740776B
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- main body
- generating main
- self energizing
- cardioverter defibrillators
- heart
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Abstract
The present invention provides a kind of self energizing Ventricular resynchronization cardioverter defibrillators, with rhythm of the heart monitoring portion, impulse generator, stimulating electrode and Power Generation Section.Power Generation Section includes generating main body, output unit, energy storage unit, fixed cell and encapsulated layer.Wherein, generating main body is multi-layer film structure, including positioned at the piezoelectric material layer of generating main center, and the electrode layer positioned at piezoelectric material layer both sides, and generating main body is used to produce electric energy by being attached at heart surface to gather cardiac energy.Output unit is connected with electrode layer, for electric current to be exported to energy storage unit.Energy storage unit is that impulse generator and stimulating electrode are powered.Fixed cell is located at the edge of generating main body, for generating main body to be fixed on into the external membrane of heart.Encapsulated layer is covered in the surface of generating main body, output unit, energy storage unit and fixed cell.It can be employed without changing battery all the life after the self energizing Ventricular resynchronization cardioverter defibrillators implantation of the present invention.
Description
Technical field
The present invention relates to a kind of Ventricular resynchronization cardioverter defibrillators, belong to medical instruments field.
Background technology
As the mankind deepen continuously to the understanding of various diseases, increasing disease can use implanted electronics
Device is diagnosed or treated.
, can be by being implanted into Ventricular resynchronization cardioverter defibrillators for there is the nonsynchronous Serious heart Failure patient of ventricular contraction
Treated, to improve the heart function of patient, mitigate the symptoms of heart failure of patient.But the existing Ventricular resynchronization implanted
Cardioverter defibrillators use battery as power supply, and its service life is 3-6.Once the energy content of battery is exhausted, it is necessary to pass through operation
Mode change battery.This can both cause physiology and psychological pain to patient, can also increase the economy of patient and its family
Burden.
The content of the invention
To solve the above problems, the present invention provides a kind of self energizing Ventricular resynchronization cardioverter defibrillators, it is characterised in that tool
There are rhythm of the heart monitoring portion, impulse generator, stimulating electrode and Power Generation Section.Power Generation Section includes generating main body, output unit, electric energy and deposited
Storage unit, fixed cell and encapsulated layer.Wherein, generating main body is multi-layer film structure, including positioned at generating main center
Piezoelectric material layer, and the electrode layer positioned at piezoelectric material layer both sides, generating main body is by being attached at heart surface to gather the heart
Dirty energy is used to produce electric energy.Output unit is connected with electrode layer, and the electric current for generating main body to be produced is exported to electric energy
Memory cell.Energy storage unit is for storing electric energy and being that impulse generator and stimulating electrode are powered.Fixed cell is located at hair
The edge of electric main body, for generating main body to be fixed on into the external membrane of heart.Encapsulated layer is covered in generating main body, output unit, electric energy and deposited
The surface of storage unit and fixed cell.
In addition, in the self energizing Ventricular resynchronization cardioverter defibrillators of the present invention, can also have the feature that:Its
In, generating main body is shaped as quadrangle, and fixed cell is located at the centre on two narrow sides of quadrangle.
In addition, in the self energizing Ventricular resynchronization cardioverter defibrillators of the present invention, can also have the feature that:Its
In, generating main body is shaped as triangle, and fixed cell is located at three summits of triangle.
In addition, in the self energizing Ventricular resynchronization cardioverter defibrillators of the present invention, can also have the feature that:Its
In, generating main body is shaped as Long Circle.
In addition, in the self energizing Ventricular resynchronization cardioverter defibrillators of the present invention, can also have the feature that:Its
In, piezoelectric material layer contains nanoscale piezoelectric, and nanoscale piezoelectric is that piezo-electric crystal, piezoelectric ceramics and organic piezoelectricity are poly-
Any one in compound.
In addition, in the self energizing Ventricular resynchronization cardioverter defibrillators of the present invention, can also have the feature that:Its
In, piezo-electric crystal is at least one layer of zinc oxide nano-wire array.
In addition, in the self energizing Ventricular resynchronization cardioverter defibrillators of the present invention, can also have the feature that:Its
In, piezo-electric crystal, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
In addition, in the self energizing Ventricular resynchronization cardioverter defibrillators of the present invention, can also have the feature that:Its
In, output unit has output electrode and current rectifying and wave filtering circuit.
In addition, in the self energizing Ventricular resynchronization cardioverter defibrillators of the present invention, can also have the feature that:Its
In, the flexible macromolecule insulating materials of encapsulated layer using good biocompatibility is used as encapsulating material.
The effect of invention and effect
According to the self energizing Ventricular resynchronization cardioverter defibrillators of the present invention, because generating main body is attached directly to heart table
Face, therefore, it is possible to effectively deform upon nanoscale piezoelectric the contraction of heart and diastole, so as to be converted into electric energy.Cause
As long as this heartbeat, the present invention provides electric energy using the biological energy source of patient itself, eliminates and uses battery as electricity
The necessity in source, solving after the energy content of battery is exhausted needs the problem of battery is changed in operation.
Further, since electricity generation system is fixed on the external membrane of heart, a side by the generating main body of the present invention by the way of point is fixed
Face can effectively gather the energy of heart movement generation, on the other hand also the contraction and diastole campaign of heart will not be produced bright
Aobvious influence.
, not only can be effectively by internal biological energy source due to the present invention using nanoscale piezoelectric as generating main body
Electric energy is converted into, and volume is small, is more suitable for et al. Ke.
Further, since the present invention is encapsulated using the flexible macromolecule insulating materials of good biocompatibility, therefore it will can send out
Electric main body is isolated with vivo environment, can also effectively conduct the heart-shaped pressure for becoming generation to piezoelectric.
Also, because the generating main body of the present invention is located at heart exterior, do not contacted directly with blood, thus in the absence of thrombus
Formed and apoplexy(Miocardial infarction or cerebral infarction)Risk.
Brief description of the drawings
Fig. 1 is the generating main body of the self energizing Ventricular resynchronization cardioverter defibrillators of the embodiment of the present invention one showing for quadrangle
It is intended to;
Fig. 2 is the partial cross section of the generating main body of the self energizing Ventricular resynchronization cardioverter defibrillators of the embodiment of the present invention one
Figure;
Fig. 3 is the generating main body of the self energizing Ventricular resynchronization cardioverter defibrillators of the embodiment of the present invention two showing for triangle
It is intended to;
Fig. 4 is that the generating main body of variation of the present invention is the schematic diagram of Long Circle;And
Fig. 5 is the circuit diagram of the embodiment of the present invention.
Embodiment
Illustrate the embodiment of self energizing Ventricular resynchronization cardioverter defibrillators of the present invention below in conjunction with accompanying drawing,
<Embodiment one>
Fig. 1 is that the generating main body of self energizing Ventricular resynchronization cardioverter defibrillators in embodiment 1 is the schematic diagram of quadrangle, such as
Shown in Fig. 1, self energizing Ventricular resynchronization cardioverter defibrillators 20 have Power Generation Section 200, rhythm of the heart monitoring portion(Do not shown in figure), pulse
Generator 17 and stimulating electrode 18.Wherein, Power Generation Section 200 includes generating main body 21, output unit, energy storage unit 16, solid
Order member 22 and encapsulated layer.Generating main body 21 is rectangle, respectively has a fixed cell 22 on two narrow sides of rectangle, is used
It is fixed in by generating main body 11 with long axis direction along systaltic direction on the external membrane of heart.When being implanted into generating main body, pass through
The mode of surgical operation manifests heart, and generating main body is set along systaltic direction and fixed part is sewn to outside the heart
On film so that generating main body fits with the external membrane of heart, now generating main body can produce deformation with the bounce of heart.
Fixed cell 22 is made up of encapsulated layer, and the inside of fixed cell 22 does not have the generating knot such as electrode or piezoelectric
Structure, therefore the electrification structure of generating main body 21 will not be destroyed when being fixed using suture.Generating main body 21 is except with fixed cell
Remainder is not fixed outside 22 fixations, in favor of enabling generating main body 21 preferably to send out during heart contraction
Raw deformation.Because generating main body employs rectangle, and installation direction is consistent with systaltic direction, therefore can be very good
Gather the mechanical energy that heart contraction is produced.
Output unit has output electrode 14 and current rectifying and wave filtering circuit 15, and output electrode 14 is used to produce generating main body 21
Electric energy export to energy storage unit 16, before energy storage unit 16 also have current rectifying and wave filtering circuit 15, for defeated
The electric current for going out the output of electrode 14 carries out rectifying and wave-filtering.Electric energy is supplied to self energizing Ventricular resynchronization conversion by energy storage unit 16
The impulse generator 17 of defibrillator.Impulse generator 17 carries out electro photoluminescence by stimulating electrode 18 to ventricle, realizes that ventricle is same again
Stepization is treated.
Fig. 2 is the sectional view of the generating main part of the self energizing Ventricular resynchronization cardioverter defibrillators of the embodiment of the present invention,
Generating main body 21 is multi-layer film structure, as shown in Fig. 2 the central core of generating main body 21 is piezoelectric material layer 31, in this implementation
In example, piezoelectric material layer 31 is made up of ZnO nanowire array, and the both sides of piezoelectric material layer 31 are respectively electrode layer 32 and electrode layer
33, electrode layer 32 and electrode layer 33 are connected with output electrode 14 respectively(Do not shown in figure).Encapsulated layer 34 is located at electrode layer 32
With the outside of electrode layer 33, encapsulated layer 34 has good insulating properties and biocompatibility.
Fig. 5 is the circuit diagram of the embodiment of the present invention, as shown in figure 5, generating main body 21 is connected with current rectifying and wave filtering circuit 15,
The electric energy that generating main body 21 is produced charges after current rectifying and wave filtering circuit 15 to energy storage unit 16, energy storage unit
16 are used to be that rhythm of the heart monitoring portion in the present embodiment and impulse generator are powered for electrical appliance.
<Embodiment two>
Fig. 3 is that the Power Generation Section of the embodiment of the present invention is the self energizing Ventricular resynchronization cardioverter defibrillators schematic diagram of triangle,
As shown in figure 3, the present invention self energizing Ventricular resynchronization cardioverter defibrillators 11 generating main body 12 be triangle, triangle it is every
Individual vertex position is respectively provided with a fixed cell 13, output electrode 14 and electrode layer(See Fig. 2)It is connected, current rectifying and wave filtering circuit 15
It is connected with output electrode 14, energy storage unit 16 is used to store Power Generation Section generation after being connected to current rectifying and wave filtering circuit 15
Electric energy.
Fig. 2 is the sectional view of the self energizing Ventricular resynchronization cardioverter defibrillators of the embodiment of the present invention, as shown in Fig. 2 generating electricity
The central core of main body is piezoelectric material layer 31, and piezoelectric material layer 31 is made up of ZnO nanowire array, the both sides of piezoelectric material layer 31
Respectively electrode layer 32 and electrode layer 33, electrode layer 32 and electrode layer 33 are connected with output electrode 14 respectively.Encapsulated layer 34
In the outside of electrode layer electrode layer 32 and electrode layer 33.The surface of actually whole self energizing Ventricular resynchronization cardioverter defibrillators 11
The encapsulated layer 34 of one layer of good insulating is all covered with, macromolecule polymeric material can be used in encapsulated layer 34, and encapsulated layer 34 has
Good biocompatibility so that self energizing Ventricular resynchronization cardioverter defibrillators 11 will not cause rejection anti-when implanting
Should.
As shown in figure 3, generating main body 12 is shaped as triangle, when being installed on the external membrane of heart, using positioned at three
Generating main body 12 is fixed on the external membrane of heart of myocardial wall by the fixed cell 13 on angular three summits.And the three of generating main body 12
Each angular side is not fixed, contraction and diastole so both without limitation on heart, additionally aids piezoelectric material layer with the heart
Dirty motion deforms upon to produce electric energy.
The advantage that generating main body 12 makes triangularity is that can more gather the energy of heartbeat, because
The not only contraction and diastole of transverse direction, also has longitudinal contraction and diastole, when using triangle during heartbeat
During shape, a summit of triangle is set to the direction towards the apex of the heart, and two other summit is set to laterally receive with heart
The direction of contracting is parallel, and so whether heart cross-direction shrinkage is longitudinal contraction, can drive generating main body 12 to deform.Therefore
The shape of triangle can more utilize the energy of heartbeat generation than the shape of quadrangle.
Fixed cell 13 is extended by encapsulated layer and formed in corresponding position, and the inside of fixed cell 13 does not contain piezoresistive material
Material and electrode material, therefore damage piezoelectric material layer and electrode layer in suture can be avoided.
<Variation>
This variation compared with embodiment one, except generating main body be shaped as Long Circle in addition to, others set homogeneous
Together.As shown in figure 4, generating main body 42 is shaped as Long Circle, in two apexes of Long Circle there is fixed cell 41, generate electricity
The advantage for being shaped as Long Circle of main body 42 is, without sharp corner, to help to mitigate the damage to heart.
Certainly, the shape of the generating main body of self energizing Ventricular resynchronization cardioverter defibrillators of the invention can be a variety of shapes
Shape, is not limited only to triangle, quadrangle and Long Circle in above-mentioned two embodiment.
Claims (9)
1. a kind of self energizing Ventricular resynchronization cardioverter defibrillators, it is characterised in that including:
Monitoring portion for monitoring cardiac electrical activity;
Impulse generator for producing electro photoluminescence;
The stimulating electrode being connected with the impulse generator;And
The Power Generation Section powered for the monitoring portion and impulse generator,
Wherein, the Power Generation Section includes generating main body, output unit, energy storage unit, fixed cell and encapsulated layer,
The generating main body is multi-layer film structure, including positioned at the piezoelectric material layer of the generating main center, and be located at
The electrode layer of piezoelectric material layer both sides, the generating main body is used to produce electricity by being attached at heart surface to gather cardiac energy
Can,
The output unit is connected with the electrode layer, and the electric current for generating main body to be produced is exported to the power storage
Unit,
The energy storage unit is used to store electric energy and powered for the monitoring portion and impulse generator,
The fixed cell is located at the edge of the generating main body, is pasted for generating main body to be fixed along systaltic direction
Together in the external membrane of heart,
The encapsulated layer is covered in the generating main body, the output unit, the energy storage unit and the fixed list
The surface of member.
2. self energizing Ventricular resynchronization cardioverter defibrillators as claimed in claim 1, it is characterised in that:
Wherein, the generating main body is shaped as quadrangle, and the centre that the fixed cell is located at two narrow sides of quadrangle makes
The generating main body is fixed along the systaltic direction with long axis direction and fits in the external membrane of heart.
3. self energizing Ventricular resynchronization cardioverter defibrillators as claimed in claim 1, it is characterised in that:
Wherein, the generating main body is shaped as triangle, and three summits that the fixed cell is located at triangle make the hair
Two summits of electric main body fit in the external membrane of heart parallelly with the direction of heart cross-direction shrinkage.
4. self energizing Ventricular resynchronization cardioverter defibrillators as claimed in claim 1, it is characterised in that:
Wherein, the generating main body is shaped as Long Circle, the fixed cell be located at the Long Circle two summits make it is described
Generating main body is fixed along the systaltic direction with long axis direction and fits in the external membrane of heart.
5. self energizing Ventricular resynchronization cardioverter defibrillators as claimed in claim 1, it is characterised in that:
Wherein, the piezoelectric material layer contains nanoscale piezoelectric, and the nanoscale piezoelectric is piezo-electric crystal, piezoelectricity pottery
Any one in porcelain and organic piezopolymer.
6. self energizing Ventricular resynchronization cardioverter defibrillators as claimed in claim 5, it is characterised in that:
Wherein, the piezo-electric crystal is at least one layer of zinc oxide nano-wire array.
7. self energizing Ventricular resynchronization cardioverter defibrillators as claimed in claim 5, it is characterised in that:
Wherein, the piezo-electric crystal, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift of nanoscale piezoelectric
Structure.
8. self energizing Ventricular resynchronization cardioverter defibrillators as claimed in claim 1, it is characterised in that:
Wherein, output unit has output electrode and current rectifying and wave filtering circuit.
9. self energizing Ventricular resynchronization cardioverter defibrillators as claimed in claim 1, it is characterised in that:
Wherein, the flexible macromolecule insulating materials of the encapsulated layer using good biocompatibility is used as encapsulating material.
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CN108379740A (en) * | 2018-01-19 | 2018-08-10 | 南华大学 | A kind of self energizing device and its installation method |
CN112436757A (en) * | 2019-08-26 | 2021-03-02 | 河北工程大学 | Micro-nano flexible power generation system of heart |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101394807A (en) * | 2005-12-12 | 2009-03-25 | 弗吉尼亚州立大学 | Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials |
CN203989481U (en) * | 2013-12-26 | 2014-12-10 | 中国人民解放军第二军医大学 | Self energizing ventricle is synchronous cardioverter defibrillators again |
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US7729768B2 (en) * | 2005-03-25 | 2010-06-01 | Proteus Biomedical, Inc. | Implantable cardiac motion powered piezoelectric energy source |
US20100171394A1 (en) * | 2008-07-06 | 2010-07-08 | Glenn Richard A | Energy harvesting for implanted medical devices |
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CN101394807A (en) * | 2005-12-12 | 2009-03-25 | 弗吉尼亚州立大学 | Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials |
CN203989481U (en) * | 2013-12-26 | 2014-12-10 | 中国人民解放军第二军医大学 | Self energizing ventricle is synchronous cardioverter defibrillators again |
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