CN104740762B - Self energizing brain pacemaker - Google Patents
Self energizing brain pacemaker Download PDFInfo
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- CN104740762B CN104740762B CN201310731416.6A CN201310731416A CN104740762B CN 104740762 B CN104740762 B CN 104740762B CN 201310731416 A CN201310731416 A CN 201310731416A CN 104740762 B CN104740762 B CN 104740762B
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- main body
- generating main
- self energizing
- heart
- brain pacemaker
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Abstract
The present invention provides a kind of self energizing brain pacemaker, it is characterised in that including impulse generator, stimulating electrode and Power Generation Section.Power Generation Section includes generating main body, output unit, energy storage unit, fixed cell and encapsulated layer.Wherein, generating main body is multi-layer film structure, including positioned at the piezoelectric material layer of generating main center, and the electrode layer positioned at piezoelectric material layer both sides, and generating main body is used to produce electric energy by being attached at heart surface to gather cardiac energy.Output unit is connected with electrode layer, and the electric current for generating main body to be produced is exported to energy storage unit.Energy storage unit is used to store electric energy and power for impulse generator.Fixed cell is located at the edge of generating main body, for generating main body to be fixed on into the external membrane of heart.Encapsulated layer is covered in the surface of generating main body, output unit, energy storage unit and fixed cell.The self energizing brain pacemaker of the present invention need not change battery, can use all the life.
Description
Technical field
The present invention relates to a kind of self energizing brain pacemaker, belong to medical instruments field.
Background technology
As the mankind deepen continuously to the understanding of various diseases, increasing disease can use implanted electronics
Device is diagnosed or treated.
Wherein, implantation brain pacemaker can by controlled in Stimulation of The Brain motion related neural, suppression cause Parkinsonian symptoms
Abnormal signal, alleviate and even eliminate the symptoms such as the trembling of patient, stiff and slow movement, its is recovered original movable energy
Power and self-care ability.But, the battery of brain pacemaker is 5~8 years, and electricity must pass through surgical operation after exhausting
Mode changes the battery of brain pacemaker.This can both cause painful and psychological frightened and anxiety physiologically to patient, also
The financial burden of patient and its family can be increased.
The content of the invention
To solve the above problems, the present invention provides a kind of self energizing brain pacemaker, it is characterised in that including pulse generation
Device, stimulating electrode and Power Generation Section.Power Generation Section includes generating main body, output unit, energy storage unit, fixed cell and envelope
Fill layer.Wherein, generating main body is multi-layer film structure, including positioned at the piezoelectric material layer of generating main center, and positioned at pressure
The electrode layer of material layer both sides, generating main body is used to produce electric energy by being attached at heart surface to gather cardiac energy.It is defeated
Go out unit with electrode layer to be connected, the electric current for generating main body to be produced is exported to energy storage unit.Energy storage unit
For storing electric energy and being powered for impulse generator.Fixed cell is located at the edge of generating main body, for generating main body to be fixed
In the external membrane of heart.Encapsulated layer is covered in the surface of generating main body, output unit, energy storage unit and fixed cell.
In addition, in the self energizing brain pacemaker of the present invention, can also have the feature that:Wherein, generating main body
Quadrangle is shaped as, fixed cell is located at the centre on two narrow sides of quadrangle.
In addition, in the self energizing brain pacemaker of the present invention, can also have the feature that:Wherein, generating main body
Triangle is shaped as, fixed cell is located at three summits of triangle.
In addition, in the self energizing brain pacemaker of the present invention, can also have the feature that:Wherein, generating main body
It is shaped as Long Circle.
In addition, in the self energizing brain pacemaker of the present invention, can also have the feature that:Wherein, piezoelectric material layer
Containing nanoscale piezoelectric, nanoscale piezoelectric is any in piezo-electric crystal, piezoelectric ceramics and organic piezopolymer
It is a kind of.
In addition, in the self energizing brain pacemaker of the present invention, can also have the feature that:Wherein, piezo-electric crystal is
At least one layer of zinc oxide nano-wire array.
In addition, in the self energizing brain pacemaker of the present invention, can also have the feature that:Wherein, piezo-electric crystal, pressure
Electroceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
In addition, in the self energizing brain pacemaker of the present invention, can also have the feature that:Wherein, output unit has
There are output electrode and current rectifying and wave filtering circuit.
In addition, in the self energizing brain pacemaker of the present invention, can also have the feature that:Wherein, encapsulated layer is with life
The good flexible macromolecule insulating materials of thing compatibility is used as encapsulating material.
The effect of invention and effect
According to the self energizing brain pacemaker of the present invention, because generating main body is attached directly to heart surface, therefore, it is possible to have
The contraction by heart of effect deforms upon nanoscale piezoelectric with diastole, so as to be converted into electric energy.As long as therefore heart is jumped
Dynamic, the present invention provides electric energy using the biological energy source of patient itself, eliminates the necessity for using battery as power supply, solves
The energy content of battery needs the problem of battery is changed in operation after exhausting.
Further, since electricity generation system is fixed on the external membrane of heart, a side by the generating main body of the present invention by the way of point is fixed
Face can effectively gather the energy of heart movement generation, on the other hand also the contraction and diastole campaign of heart will not be produced bright
Aobvious influence.
, not only can be effectively by internal biological energy source due to the present invention using nanoscale piezoelectric as generating main body
Electric energy is converted into, and volume is small, is more suitable for et al. Ke.
Further, since the present invention is encapsulated using the flexible macromolecule insulating materials of good biocompatibility, therefore it will can send out
Electric main body is isolated with vivo environment, can also effectively conduct the heart-shaped pressure for becoming generation to piezoelectric.
Also, because the generating main body of the present invention is located at heart exterior, do not contacted directly with blood, thus in the absence of thrombus
Formed and apoplexy(Miocardial infarction or cerebral infarction)Risk.
Brief description of the drawings
Fig. 1 is that the generating main body of the self energizing brain pacemaker of the embodiment of the present invention one is the schematic diagram of quadrangle;
Fig. 2 is the partial section of the generating main body of the self energizing brain pacemaker of the embodiment of the present invention one;
Fig. 3 is that the generating main body of the self energizing brain pacemaker of the embodiment of the present invention two is the schematic diagram of triangle;
Fig. 4 is that the generating main body of variation of the present invention is the schematic diagram of Long Circle;And
Fig. 5 is the circuit diagram of the embodiment of the present invention one.
Embodiment
Illustrate the embodiment of self energizing brain pacemaker of the present invention below in conjunction with accompanying drawing,
<Embodiment one>
Fig. 1 is that the generating main body of self energizing brain pacemaker in embodiment 1 is the schematic diagram of quadrangle, as shown in figure 1, confession
Energy brain pacemaker 20 has Power Generation Section 200, impulse generator 17 and stimulating electrode 18.Wherein, Power Generation Section 200 includes generating main body
21, output unit, energy storage unit 16, fixed cell 22 and encapsulated layer.Generating main body 21 is rectangle, at two of rectangle
Respectively there is a fixed cell 22, for generating main body 11 to be fixed on long axis direction along systaltic direction on narrow side
On the external membrane of heart.When being implanted into generating main body, heart is manifested by way of surgical operation, by generating main body along systaltic
Direction, which is set, is simultaneously sewn to fixed part on the external membrane of heart so that generating main body fits with the external membrane of heart, and now generating main body can be with
The bounce for heart produces deformation.
Fixed cell 22 is made up of encapsulated layer, and the inside of fixed cell 22 does not have the generating knot such as electrode or piezoelectric
Structure, therefore the electrification structure of generating main body 21 will not be destroyed when being fixed using suture.Because generating main body employs rectangle, and
And installation direction is consistent with systaltic direction, therefore it can be very good to gather the mechanical energy that heart contraction is produced.
The remainder in addition to being fixed with fixed cell 22 of generating main body 21 is not fixed, in favor of systaltic
During generating main body 21 is preferably deformed upon.Output unit has output electrode 14 and current rectifying and wave filtering circuit
15, the electric energy that output electrode 14 is used to produce generating main body 21 is exported to energy storage unit 16, in energy storage unit 16
Also there is current rectifying and wave filtering circuit 15 before, the electric current for being exported to output electrode 14 carries out rectifying and wave-filtering.Energy storage unit
16 are supplied to electric energy the impulse generator 17 of self energizing brain pacemaker.Stimulating electrode 18 is implanted into encephalic, and impulse generator 17 is produced
Raw high frequency electric pulse stimulates brain to control the related neural of motion by stimulating electrode 18, suppresses to cause the exception of Parkinsonian symptoms
Signal.
Fig. 2 is the sectional view of the generating main part of the self energizing brain pacemaker of the embodiment of the present invention, and generating main body 21 is
Multi-layer film structure, as shown in Fig. 2 the central core of generating main body 21 is piezoelectric material layer 31, in the present embodiment, piezoelectric
Layer 31 is made up of ZnO nanowire array, and the both sides of piezoelectric material layer 31 are respectively electrode layer 32 and electrode layer 33, the He of electrode layer 32
Electrode layer 33 is connected with output electrode 14 respectively(Do not shown in figure).Encapsulated layer 34 is located at the outer of electrode layer 32 and electrode layer 33
Side, encapsulated layer 34 has good insulating properties and biocompatibility.
Fig. 5 is the circuit diagram of the embodiment of the present invention, as shown in figure 5, generating main body 21 is connected with current rectifying and wave filtering circuit 15,
The electric energy that generating main body 21 is produced charges after current rectifying and wave filtering circuit 15 to energy storage unit 16, energy storage unit
16 for being that the impulse generator in the present embodiment is powered for electrical appliance.
<Embodiment two>
Fig. 3 is that the Power Generation Section of the embodiment of the present invention is the self energizing brain pacemaker schematic diagram of triangle, as shown in figure 3, this
The generating main body 12 of the self energizing brain pacemaker 11 of invention is triangle, and each vertex position of triangle is respectively provided with a fixation
Unit 13, output electrode 14 and electrode layer(See Fig. 2)It is connected, current rectifying and wave filtering circuit 15 is connected with output electrode 14, electric energy
Memory cell 16 is used to store the electric energy that Power Generation Section is produced after being connected to current rectifying and wave filtering circuit 15.
Fig. 2 is the sectional view of the self energizing brain pacemaker of the embodiment of the present invention, as shown in Fig. 2 the central core of generating main body
For piezoelectric material layer 31, piezoelectric material layer 31 is made up of ZnO nanowire array, and the both sides of piezoelectric material layer 31 are respectively electrode layer
32 and electrode layer 33, electrode layer 32 and electrode layer 33 are connected with output electrode 14 respectively.Encapsulated layer 34 is located at electrode layer electrode
The outside of layer 32 and electrode layer 33.The surface of actually whole self energizing brain pacemaker 11 is all covered with the envelope of one layer of good insulating
Layer 34 is filled, macromolecule polymeric material can be used in encapsulated layer 34, and encapsulated layer 34 has good biocompatibility so that confession
Energy brain pacemaker 11 will not cause rejection when implanting.
As shown in figure 3, generating main body 12 is shaped as triangle, when being installed on the external membrane of heart, using positioned at three
Generating main body 12 is fixed on the external membrane of heart of myocardial wall by the fixed cell 13 on angular three summits.And the three of generating main body 12
Each angular side is not fixed, contraction and diastole so both without limitation on heart, additionally aids piezoelectric material layer with the heart
Dirty motion deforms upon to produce electric energy.
The advantage that generating main body 12 makes triangularity is that can more gather the energy of heartbeat, because
The not only contraction and diastole of transverse direction, also has longitudinal contraction and diastole, when using triangle during heartbeat
During shape, a summit of triangle is set to the direction towards the apex of the heart, and two other summit is set to laterally receive with heart
The direction of contracting is parallel, and so whether heart cross-direction shrinkage is longitudinal contraction, can drive generating main body 12 to deform.Therefore
The shape of triangle can more utilize the energy of heartbeat generation than the shape of quadrangle.
Fixed cell 13 is extended by encapsulated layer and formed in corresponding position, and the inside of fixed cell 13 does not contain piezoresistive material
Material and electrode material, therefore damage piezoelectric material layer and electrode layer in suture can be avoided.
Electric energy is supplied to the energy storage unit 16 of biological energy source self energizing brain pacemaker by electric energy by energy storage unit 16
It is supplied to the impulse generator 17 of self energizing brain pacemaker.Impulse generator 17 produces high frequency electric pulse and pierced by stimulating electrode 18
Swash the related neural of intracerebral control motion, suppress to cause the abnormal signal of Parkinsonian symptoms.
<Variation>
This variation compared with embodiment one, except generating main body be shaped as Long Circle in addition to, others set homogeneous
Together.As shown in figure 4, generating main body 42 is shaped as Long Circle, in two apexes of Long Circle there is fixed cell 41, generate electricity
The advantage for being shaped as Long Circle of main body 42 is, without sharp corner, to help to mitigate the damage to heart.
Certainly, the shape of the generating main body of self energizing brain pacemaker of the invention can be various shapes, be not limited only to
State triangle, quadrangle and the Long Circle in two embodiments.
Claims (9)
1. a kind of self energizing brain pacemaker, it is characterised in that including:
Impulse generator for producing electro photoluminescence;
The stimulating electrode being connected with the impulse generator;And
The Power Generation Section powered for the impulse generator,
Wherein, the Power Generation Section includes generating main body, output unit, energy storage unit, fixed cell and encapsulated layer,
The generating main body is multi-layer film structure, including positioned at the piezoelectric material layer of the generating main center, and be located at
The electrode layer of piezoelectric material layer both sides, the generating main body is attached directly to heart surface to be used to produce electricity to gather cardiac energy
Can,
The output unit is connected with the electrode layer, and the electric current for generating main body to be produced is exported to the power storage
Unit,
The energy storage unit is used to store electric energy and power for the impulse generator,
The fixed cell is located at the edge of the generating main body, for by generating main body with long axis direction along systaltic
Direction is fixed on the external membrane of heart so that generating main body fits with the external membrane of heart,
The encapsulated layer is covered in the generating main body, the output unit, the energy storage unit and the fixed list
The surface of member.
2. self energizing brain pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the generating main body is shaped as quadrangle, and the centre that the fixed cell is located at two narrow sides of quadrangle makes
The generating main body is fixed along the systaltic direction with long axis direction and fits in the external membrane of heart.
3. self energizing brain pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the generating main body is shaped as triangle, and three summits that the fixed cell is located at triangle make the hair
Two summits of electric main body fit in the external membrane of heart parallelly with the direction of heart cross-direction shrinkage.
4. self energizing brain pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the generating main body is shaped as Long Circle, the fixed cell be located at the Long Circle two summits make it is described
Generating main body is fixed along the systaltic direction with long axis direction and fits in the external membrane of heart.
5. self energizing brain pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the piezoelectric material layer contains nanoscale piezoelectric, and the nanoscale piezoelectric is piezo-electric crystal, piezoelectricity pottery
Any one in porcelain and organic piezopolymer.
6. self energizing brain pacemaker as claimed in claim 5, it is characterised in that:
Wherein, the piezo-electric crystal is at least one layer of zinc oxide nano-wire array.
7. self energizing brain pacemaker as claimed in claim 5, it is characterised in that:
Wherein, the piezo-electric crystal, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift of nanoscale piezoelectric
Structure.
8. self energizing brain pacemaker as claimed in claim 1, it is characterised in that:
Wherein, output unit has output electrode and current rectifying and wave filtering circuit.
9. self energizing brain pacemaker as claimed in claim 1, it is characterised in that:
Wherein, the flexible macromolecule insulating materials of the encapsulated layer using good biocompatibility is used as encapsulating material.
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CN201310731416.6A CN104740762B (en) | 2013-12-26 | 2013-12-26 | Self energizing brain pacemaker |
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CN201310731416.6A CN104740762B (en) | 2013-12-26 | 2013-12-26 | Self energizing brain pacemaker |
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CN104740762B true CN104740762B (en) | 2017-07-18 |
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CN201310731416.6A Expired - Fee Related CN104740762B (en) | 2013-12-26 | 2013-12-26 | Self energizing brain pacemaker |
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US10463864B2 (en) * | 2015-09-15 | 2019-11-05 | The Regents Of The University Of Michigan | Energy harvesting for leadless pacemakers |
CN105233407B (en) * | 2015-10-19 | 2017-11-21 | 徐醒忠 | A kind of biological electro-therapeutic apparatus and its electrotherapeutic method |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101394807A (en) * | 2005-12-12 | 2009-03-25 | 弗吉尼亚州立大学 | Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials |
CN204073100U (en) * | 2013-12-26 | 2015-01-07 | 中国人民解放军第二军医大学 | Self energizing brain pacemaker |
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US7729768B2 (en) * | 2005-03-25 | 2010-06-01 | Proteus Biomedical, Inc. | Implantable cardiac motion powered piezoelectric energy source |
WO2010005915A2 (en) * | 2008-07-06 | 2010-01-14 | Synecor Llc | Energy harvesting for implanted medical devices |
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CN101394807A (en) * | 2005-12-12 | 2009-03-25 | 弗吉尼亚州立大学 | Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials |
CN204073100U (en) * | 2013-12-26 | 2015-01-07 | 中国人民解放军第二军医大学 | Self energizing brain pacemaker |
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Granted publication date: 20170718 Termination date: 20171226 |