CN104686511A - Novel efficient sterilizing and bacteriostatic agent - Google Patents

Novel efficient sterilizing and bacteriostatic agent Download PDF

Info

Publication number
CN104686511A
CN104686511A CN201310662654.6A CN201310662654A CN104686511A CN 104686511 A CN104686511 A CN 104686511A CN 201310662654 A CN201310662654 A CN 201310662654A CN 104686511 A CN104686511 A CN 104686511A
Authority
CN
China
Prior art keywords
hyperbranched polyethylene
detection method
hyperbranched
rate
described detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201310662654.6A
Other languages
Chinese (zh)
Other versions
CN104686511B (en
Inventor
相鹏
李晓倩
王静
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
XI'AN IAMTECH POLYMER MATERIAL Ltd
Original Assignee
XI'AN IAMTECH POLYMER MATERIAL Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by XI'AN IAMTECH POLYMER MATERIAL Ltd filed Critical XI'AN IAMTECH POLYMER MATERIAL Ltd
Priority to CN201310662654.6A priority Critical patent/CN104686511B/en
Publication of CN104686511A publication Critical patent/CN104686511A/en
Application granted granted Critical
Publication of CN104686511B publication Critical patent/CN104686511B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a novel efficient sterilizing and bacteriostatic agent, belonging to the technical field of bacteria resistance and bacteriostasis. The novel efficient sterilizing and bacteriostatic agent mainly relates to the sterilizing and bacteriostatic effect of a hyperbranched polyolefin compound (HBP); and the hyperbranched polyolefin is applicable to the fields of various household chemicals, medicines and the like, and is the novel efficient sterilizing and bacteriostatic agent.

Description

A kind of new and effective sterilization bacteriostat
Technical field
The present invention relates to a kind of new and effective sterilization bacteriostat, belong to antibacterial bacteriostatic technical field.Described invention relates generally to hyperbranched polyolefinic bactericidal and bacteriostatic effect, it can kill Escherichia coli, staphylococcus aureus, green copper pseudomonad, colon bacillus etc., has the characteristics such as composition is single, antimicrobial efficiency is high, broad-spectrum antibacterial, stable performance, effect length, safety non-toxic, nonirritant.This kind of hyperbranched poly alkene is applicable to various daily chemical products, medicine and other fields, is a kind of new and effective sterilization bacteriostat.
Background technology
Antibacterial agent within a certain period of time, to make the growth of certain micro-organisms (bacterium, fungi, saccharomycete, algae and virus etc.) or breeding remain on chemical substance necessary below horizontal.Antibacterial agent is that a class has antibacterial and New-type adjuvant that is bactericidal property.Bacteria growing inhibiting, reduce bacterium to the harm of the mankind, various novel anti-biotic material continues to bring out out, is especially with a wide range of applications at medical treatment, health industry.The antibacterial agent adopting easy method to prepare to have high antimicrobial efficiency and bactericide are paid close attention to by domestic and international always.Antibacterial agent is divided into the large class of inorganic antiseptic and organic antibacterial agent two, and wherein organic antibacterial agent is divided into again natural, low molecule and macromolecule organic antibacterial agent.Tradition low molecule organic bactericide bacteriostatic agent is volatile, not easily processing, poor chemical stability, toxicity are large, big for environment pollution, release is difficult to control, timeliness is short, high in cost of production defect.The research and development of antibacterial agent mainly concentrate on characteristics such as improving antimicrobial efficiency, stability and low toxicity.
The object of the invention is, in order to provide a kind of sterilization bacteriostat efficiently, to solve containing harmful material in traditional germicide constituent, threaten human health; The sterilization kind of bactericide traditional is in addition single, and component needs number of chemical composition, the defect that manufacturing cost is high.
Summary of the invention
In the present invention the synthetic method of one of monomer used HBPE see patent of invention 201110366937.7,201210027742.4,201210068685.4, the correlation technique of 201310248390X and 201310277998.5, its microstructure is highly branched approximate sphericity structure, and its sphere diameter is 10 -15~ 10 -17m.The invention solves the defect existed in traditional organic antibacterial agent, and provide a kind of new hyperbranched TPO antibiotic bactericide.
The antimicrobial efficiency that the object of this invention is to provide a kind of market demand is high, broad-spectrum antibacterial, stable performance, long shelf-life, safety non-toxic, the characteristic such as non-stimulated new and effective antibiotic bacteriostat.
The present invention has the following advantages compared with existing antibiotic bacteriostat: antimicrobial efficiency is high, broad-spectrum antibacterial, stable performance, long shelf-life, safety non-toxic, the characteristic such as non-stimulated new and effective antibiotic bacteriostat.
Embodiment
Below by specific embodiment, technical scheme of the present invention is described in further detail, but application of the present invention is not only confined to the scope of embodiment.
Embodiment 1
Hyperbranched hydrogenated polyvinyl and pseudomonas aeruginosa ATCC9027 activity are 1:1, and action time is 20 min, and its sterilizing rate reaches 79%.Described sterilizing rate is measured by QB/T 2738-2012.Testing result is as shown in table 1.
Embodiment 2
Hyperbranched hydrogenated polyvinyl and colon bacillus 8099 activity are 1:1, and action time is 20 min, and its sterilizing rate reaches 79%.Described sterilizing rate is measured by QB/T 2738-2012.Testing result is as shown in table 1.
Embodiment 3
Hyperbranched hydrogenated polyvinyl and staphylococcus aureus ATCC6538 activity are 1:1, and action time is 20 min, and its sterilizing rate reaches 92%.Described sterilizing rate is measured by QB/T 2738-2012.
Embodiment 4
Hyperbranched hydrogenated polyvinyl and Escherichia coli ATCC 25922 act on, and action time is 24h, its sterilizing rate > 99.98%.Described sterilizing rate passes through disinfection technology standard " version-2.1.11.3.1 measured 2002 years.Testing result is as shown in table 2.
Embodiment 5
Hyperbranched hydrogenated polyvinyl and staphylococcus aureus ATCC 6538 act on, and action time is 24h, its sterilizing rate > 99.98%.Described sterilizing rate is measured by " disinfection technology standard " version-2.1.11.3.1 in 2002.Testing result is as shown in table 2.
Embodiment 6
Hyperbranched hydrogenated polyvinyl and Escherichia coli effect, and action time be 24h, its antibiotic rate > 99.99%.Described antibiotic rate is measured by JIS Z 2801:2010.Testing result is as shown in table 3.
Embodiment 7
Hyperbranched hydrogenated polyvinyl and staphylococcus aureus ATCC 6538P effect, and action time be 24h, its antibiotic rate > 99.97%.Described antibiotic rate is measured by JIS Z 2801:2010.Testing result is as shown in table 3.
Embodiment 8
Hyperbranched hydrogenated polyvinyl and aspergillus niger * effect, and action time be 24h, its antibiotic rate is 89.09%.Described antibiotic rate is measured by JIS Z 2801:2010.Testing result is as shown in table 3.
  
the structural formula of hyperbranched polyethylene.
Experimental result is in table 1, table 2 and table 3.
The testing result of table 1 antibacterial bacteriostatic effect
The testing result of table 2 antibacterial bacteriostatic effect
The testing result of table 3 bactericidal and bacteriostatic effect
The above; it is only preferred embodiment of the present invention; not the present invention is imposed any restrictions, every above embodiment is done according to the technology of the present invention essence any simple modification, change and equivalent structure change, all still belong in the protection domain of technical solution of the present invention.

Claims (12)

1. a new and effective sterilization bacteriostat, has following structural formula:
2. according to described in claim 1, it is characterized in that, liquid hyperbranched polyethylene (HBPE) number-average molecular weight used be 300 ~ 600.
3., according to described in claim 1, hyperbranched polyethylene has 1.7 to 6.7 mm 2s -1kinematic viscosity (40 DEG C); Described kinematic viscosity is measured by GB/T 265-1988 (2004).
4., according to described in claim 1, hyperbranched polyethylene has the viscosity-temperature characteristics that viscosity index (VI) is greater than 130; Described viscosity index (VI) is measured by GB/T 1995-1998 (2004).
5. according to described in claim 1, hyperbranched polyethylene is 92% to the sterilizing rate of staphylococcus aureus ATCC6538, and described detection method is QB/T2738-2012.
6. according to described in claim 1, hyperbranched polyethylene is 79% to the sterilizing rate of pseudomonas aeruginosa ATCC9027, and described detection method is QB/T2738-2012.
7. according to described in claim 1, hyperbranched polyethylene is 79% to the sterilizing rate of colon bacillus 8099, and described detection method is QB/T2738-2012.
8. according to described in claim 1, hyperbranched polyethylene is ﹥ 99.98% to the sterilizing rate of Escherichia coli ATCC25922, and described detection method is " disinfection technology standard " version-2.1.11.3.1 in 2002.
9. according to described in claim 1, hyperbranched polyethylene is ﹥ 99.98% to the sterilizing rate of staphylococcus aureus ATCC6538, and described detection method is " disinfection technology standard " version-2.1.11.3.1 in 2002.
10., according to described in claim 1, hyperbranched polyethylene is to the antibiotic rate ﹥ 99.99% of Escherichia coli ATCC8739, and described detection method is JIS Z 2801:2010.
11. according to described in claim 1, and hyperbranched polyethylene is to the antibiotic rate ﹥ 99.97% of staphylococcus aureus ATCC 6538P, and described detection method is JIS Z 2801:2010.
12. according to described in claim 1, and hyperbranched polyethylene is 89.09% to the antibiotic rate of aspergillus niger ATCC 16404, and described detection method is JIS Z 2801:2010.
CN201310662654.6A 2013-12-10 2013-12-10 Novel efficient sterilizing and bacteriostatic agent Active CN104686511B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310662654.6A CN104686511B (en) 2013-12-10 2013-12-10 Novel efficient sterilizing and bacteriostatic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310662654.6A CN104686511B (en) 2013-12-10 2013-12-10 Novel efficient sterilizing and bacteriostatic agent

Publications (2)

Publication Number Publication Date
CN104686511A true CN104686511A (en) 2015-06-10
CN104686511B CN104686511B (en) 2017-02-08

Family

ID=53334409

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310662654.6A Active CN104686511B (en) 2013-12-10 2013-12-10 Novel efficient sterilizing and bacteriostatic agent

Country Status (1)

Country Link
CN (1) CN104686511B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106309023A (en) * 2015-07-01 2017-01-11 西安艾姆高分子材料有限公司 Production method for liquid-state organic nanoscale long-acting antibacterial sanitary towel
CN106619485A (en) * 2015-11-02 2017-05-10 西安艾姆高分子材料有限公司 Organic nanometer ointment for quickly restoring burn, scald and wound
CN106880514A (en) * 2017-03-10 2017-06-23 西安艾姆高分子材料有限公司 A kind of new organic nano material for substituting preservative
CN106913509A (en) * 2015-12-25 2017-07-04 西安艾姆高分子材料有限公司 A kind of organic nano level long-acting bacteriostatic sterilization hand lotion and preparation method thereof
CN110974727A (en) * 2019-12-27 2020-04-10 西安艾姆高分子材料有限公司 Long-acting antibacterial mouthwash and preparation method thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109197865A (en) * 2018-01-26 2019-01-15 西安艾姆高分子材料有限公司 A kind of swimming pool long-acting fungicide

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103122265A (en) * 2011-11-17 2013-05-29 西安艾姆高分子材料有限公司 Novel polyethylene synthetic lubricating oil/lubricating oil additive and preparation method thereof
CN103242118A (en) * 2012-02-08 2013-08-14 西安艾姆高分子材料有限公司 Method for synthesizing novel ethene oligomer
CN103304717A (en) * 2012-03-15 2013-09-18 西安艾姆高分子材料有限公司 Method for preparing high-viscosity-index synthetic lubricating oil through copolymerization of ethylene and alpha-olefin and applications thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103122265A (en) * 2011-11-17 2013-05-29 西安艾姆高分子材料有限公司 Novel polyethylene synthetic lubricating oil/lubricating oil additive and preparation method thereof
CN103242118A (en) * 2012-02-08 2013-08-14 西安艾姆高分子材料有限公司 Method for synthesizing novel ethene oligomer
CN103304717A (en) * 2012-03-15 2013-09-18 西安艾姆高分子材料有限公司 Method for preparing high-viscosity-index synthetic lubricating oil through copolymerization of ethylene and alpha-olefin and applications thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106309023A (en) * 2015-07-01 2017-01-11 西安艾姆高分子材料有限公司 Production method for liquid-state organic nanoscale long-acting antibacterial sanitary towel
CN106619485A (en) * 2015-11-02 2017-05-10 西安艾姆高分子材料有限公司 Organic nanometer ointment for quickly restoring burn, scald and wound
CN106913509A (en) * 2015-12-25 2017-07-04 西安艾姆高分子材料有限公司 A kind of organic nano level long-acting bacteriostatic sterilization hand lotion and preparation method thereof
CN106880514A (en) * 2017-03-10 2017-06-23 西安艾姆高分子材料有限公司 A kind of new organic nano material for substituting preservative
CN110974727A (en) * 2019-12-27 2020-04-10 西安艾姆高分子材料有限公司 Long-acting antibacterial mouthwash and preparation method thereof

Also Published As

Publication number Publication date
CN104686511B (en) 2017-02-08

Similar Documents

Publication Publication Date Title
CN104686511B (en) Novel efficient sterilizing and bacteriostatic agent
AU2009204189B2 (en) Disinfectant alcohol-soluble quaternary ammonium polymers
CN102246753A (en) Compound quaternary ammonium salt disinfectant
Abi-Ayad et al. Antibacterial activity of Pinus halepensis essential oil from Algeria (Tlemcen)
AU2015234234A1 (en) Antimicrobial sanitizer compositions and their use
CN105670078A (en) Antistatic and antibacterial plastics and preparation method
Sajeshkumar et al. Synthesis of silver nanoparticles from neem leaf (Azadirachta indica) extract and its antibacterial activity
CN108684660A (en) A kind of long-acting bacteriostatic disinfectant containing plants essential oil and preparation method
US9095731B2 (en) Anti-microbial composition
CN104559648A (en) Bactericidal coating
CN103891772B (en) A kind of compound disinfecting antibacterial
Salman Evaluation and comparison the antibacterial activity of silver nano particles (AgNPs) and silver nitrate (AgNO3) on some pathogenic bacteria
Alam et al. Highly sustained release of bactericides from complex coacervates
Dubey et al. Evalution of antibacterial and antioxidant activity of methanolic and hydromethanolic extract of sweet orange peels
Kader Effects of nano-silver holding and pulse treatments, in comparison with traditional silver nitrate pulse on water relations and vase life and quality of the cut flowers of Rosa hybrida l. cv.‘tineke’
CN107412213B (en) Multifunctional external antibacterial and sterilizing agent and preparation method thereof
Suryawanshi et al. Formulation, evaluation and anti-microbial efficiency of alcohol based herbal hand sanitizer
CN111418587A (en) Efficient household fabric disinfectant and preparation method thereof
CN106665649A (en) Daily chemical product bacteriostat and preparation method thereof
CN104686578A (en) Composite antibacterial powder
Eliasa et al. Evaluation of efficacy of disinfectants using standard methods in healthcare facilities in Kogi state, Northcentral Nigeria
JP6417503B1 (en) Antibacterial agent that maintains antibacterial and antifungal properties for a long time by using platinum shield technology and antibacterial composition using the same
CN108605976B (en) Antibacterial agent for inhibiting and killing bacteria
Bouryabaf et al. Biofilm removal and antimicrobial activities of agar hydrogel containing colloid nano-silver against Staphylococcus aureus and Salmonella typhimurium
Mahami et al. Comparative susceptibility of in vitro biofilm and planktonic cells of Staphylococcus aureus to antimicrobials

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant