CN108684660A - A kind of long-acting bacteriostatic disinfectant containing plants essential oil and preparation method - Google Patents

A kind of long-acting bacteriostatic disinfectant containing plants essential oil and preparation method Download PDF

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Publication number
CN108684660A
CN108684660A CN201710226094.8A CN201710226094A CN108684660A CN 108684660 A CN108684660 A CN 108684660A CN 201710226094 A CN201710226094 A CN 201710226094A CN 108684660 A CN108684660 A CN 108684660A
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China
Prior art keywords
essential oil
disinfectant
long
oil
plants essential
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CN201710226094.8A
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Chinese (zh)
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不公告发明人
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Aiboston (shenzhen) Biotechnology Co Ltd
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Aiboston (shenzhen) Biotechnology Co Ltd
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Priority to CN201710226094.8A priority Critical patent/CN108684660A/en
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A01N65/12—Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Pest Control & Pesticides (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Botany (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A kind of long-acting bacteriostatic disinfectant containing plants essential oil and preparation method, belong to the technical field of disinfectant.Purpose of the present invention is to be directed to current most of disinfectants not having long-acting bacteriostatic function, smell is pungent, and oxidisability is strong, and destruction is led to the problem of to skin and other action faces.The disinfectant is PEI(10%),PHMB(20%), Artemisia oil, plants essential oil, Tween 80, made of edible alcohol and deionized water.The method of the present invention:By PEI(10%)And PHMB(20%)It is dissolved in deionized water, and Artemisia oil and plants essential oil is added, vibration of ultrasonic wave 1~5 minutes;Then Tween 80 mixing is added, adds95%Edible alcohol, vibration of ultrasonic wave.The present invention can reduce disinfectant access times while not reducing disinfection effect, reduce wasting of resources environmental pollution.Present invention safety, it is nontoxic, it is nonirritant, bacterium is used for a long time and does not develop immunity to drugs and there is long-effective protection effect.

Description

A kind of long-acting bacteriostatic disinfectant containing plants essential oil and preparation method
Technical field
The invention belongs to the technical fields of disinfectant;More particularly to a kind of long-acting bacteriostatic disinfectant containing plants essential oil and preparation side Method.
Background technology
The sterilizing of medical instrument, life and office daily necessities etc. is particularly important.
Although current existing sterilizing product is very more, most products have been often accompanied by using the method for chemistry Penetrating odor, corrosivity or have residual etc. toxic side effects, certain threat is caused to health.It is with chlorine-containing disinfectant Example, chlorine-containing disinfectant have the advantages that cheap, efficient, are widely used in drinking water disinfection, environment disinfected, the necks such as health care disinfection Domain is to use to obtain widest a kind of disinfectant in the world at present.
However chlorine-containing disinfectant has the disadvantages that:Hypochlorous acid molecule decomposes release gas C1 in water2, gas C12No Environment is only polluted, but also can cause to shed tears, cough, skin and mucous membrane, severe patient is stimulated to cause to be poisoned, be choked to death and die.When When larger using concentration, people is unsuitable on the scene.Therefore, chlorine-containing disinfectant should not generally be applied to disinfection of indoor air.Have stronger Irritation generally should not be applied to human skin and mucous membrane sterilizes.Therefore a kind of safe and efficient disinfectant is to environmental protection, Human health has great importance, and social benefit is far-reaching.
Invention content
Purpose of the present invention is to be directed to current most of disinfectants not having long-acting bacteriostatic function, smell is pungent, and oxidisability is strong, Destruction is led to the problem of to skin and other action faces;And it provides a kind of long-acting bacteriostatic disinfectant containing plants essential oil and prepares Method.
A kind of long-acting bacteriostatic disinfectant containing plants essential oil is made of following raw materials in the present invention:PEI(10%)(Glass Enhance 10% PEI polyetherimide),PHMB(20%)(Hexamethylene PHMB20% aqueous solutions), Artemisia oil, Plants essential oil, Tween 80, edible alcohol and deionized water.
Plants essential oil be eucalyptus quintessence oil, tea tree ethereal oil, orange essential oil, dried orange peel essential oil, Rosa Damascana, lemon grass (Cymbopogon citratus) essential oil, Peppermint essential oil, thyme essential oil, clove oil, yulan flower essential oil, wormwood essential oil, Lavender, lemon or green tea essence Oil.
In terms of parts by weight, the proportioning of each raw material is:3 parts ~ 6.4 parts PEI(10%), 1.5 parts ~ 3.6 parts of PHMB (20%), 0.099 part ~ 0.186 part of Artemisia oil, 1.21 parts ~ 2.28 parts plants essential oils, 0.02 part ~ 0.35 part Tween 80,0.01 Made of part ~ 68.5 part of 95% edible alcohol and 309.17 parts ~ 990.37 parts deionized waters.
A kind of preparation method of long-acting bacteriostatic disinfectant containing plants essential oil of the present invention presses step progress:30 ~ 50 DEG C, under the conditions of 500-700rpm, by PEI(10%)And PHMB(20%)Magnetic agitation 10-12 hours, is then completely dissolved in In ionized water, Artemisia oil and plants essential oil, vibration of ultrasonic wave 1 are added~Form the micro- sol solution of milky within 5 minutes;Then it is added Tween 80 enables solution be uniformly mixed, adds using vortex agitator95%Edible alcohol, vibration of ultrasonic wave 1~It is formed within 3 minutes steady Fixed translucent solution;Obtain disinfectant.
The present invention can action face generate long-acting bacteriostatic film, fungistatic effect for different bacterium up to several weeks to the several months not Deng, under laboratory condition, long-acting bacteriostatic film formed three months after still may be used to the bacteriostasis rate of staphylococcus aureus and Escherichia coli Reach 98% or more, can also generate killing and inhibiting effect to multiple drug resistant bacteria.The present invention uses physical sterilization principle, through sweeping Electron microscope confirmation is retouched, sterilization component is attached to bacterium surface, its metabolism is blocked to lead to bacterial death, does not easily cause thin Bacterium generates drug resistance.There is this formula multiple sterilizations effect, the sterilization synergist in the present invention can quickly kill attached bacteria, liquid The bacteriostatic film generated after body volatilization has and long-acting bacteriostatic effect.The present invention contains plants essential oil, and natural aromatic is free of essence, peace Atoxic, no obvious irritation smell.According to the difference of added plants essential oil, this formula, which also has, to refresh the mind, and tranquilizing the mind helps Sleep and other effects.
The present invention utilizes the broad-spectrum sterilization effect of cationic surfactant and reduces the surface tension of monomer and water Pure natural sterilization component-the plants essential oil of oiliness is dissolved in deionized water by characteristic.And it is steady under ul-trasonic irradiation, being formed The micro- sol solution of fixed nanoscale, plants essential oil is wrapped in high molecular nanometer shell.The speed that evaporates can be improved in alcohol.It will After thimerosal is sprayed at action face, it can quickly kill and cure the disease bacterium and form antibacterial film, plants essential oil is via nanometer shell Empty slow release generates the effect of long-acting bacteriostatic.The different additions or removal of the visual action face of alcohol.
The present invention is directed to family, office space, mobile phone and other electronic products etc., under the premise of not reducing bactericidal effect Disinfectant access times are reduced, wasting of resources environmental pollution is reduced.This formula can be used for the electronic equipments such as mobile phone plane plate computer with And daily necessities surface of living and handle official business, prevent spread of germs, cross infection of disease.
Specific implementation mode
Specific implementation mode one:A kind of long-acting bacteriostatic disinfectant containing plants essential oil of present embodiment be by5.4ml PEI (10%),2.5mlPHMB(20%),0.125gArtemisia oil,2.28gEucalyptus quintessence oil,0.10mlTween 80,68 ml95%It is edible Alcohol and800mlMade of deionized water;Specifically press step progress:
At 30 ~ 50 DEG C, by PEI under the conditions of 500-700rpm(10%)And PHMB(20%)Magnetic agitation 12 hours, it is then fully molten Solution adds Artemisia oil and plants essential oil, vibration of ultrasonic wave 1 in deionized water~Form the micro- sol solution of milky within 5 minutes;So After Tween 80 is added, using vortex agitator enable solution be uniformly mixed, add95%Edible alcohol, vibration of ultrasonic wave 1~3 minutes Translucent solution is stablized in formation;Obtain disinfectant.
The disinfectant Soak Test microorganism suspension of present embodiment preparation 5 minutes, then applies the soak of 100 μ L Smear in being cultivated on agar plate, measure its to Pseudomonas aeruginosa (PA, ATCC15442 reference culture), Escherichia coli (EC, ATCC35401 reference cultures), Staphylococcus aureus (SA, ATCC259231 reference culture), Candida albicans (CA, ATCC1023 Reference culture) and black-koji mould (AN, ATCC16404 reference culture) killing effect, test bacterial concentration be 1 × 107~5 × 107Blank control group is arranged in CFU/mL.Neutralizer is the phosphate buffer solution of 0.3% soft phosphatide and 3% Tween 80 (PBS).As a result, it has been found that sterile on the agar of sample sets drop out now, and control group agar surface is paved with microorganism, illustrates tested micro- Biological growth is in order.The result shows that above-mentioned antimicrobial macromolecule disinfectant is good to the effect of mentioned microorganism, 5 points are impregnated Clock reaches 99.99% killing effect.

Claims (5)

1. a kind of long-acting bacteriostatic disinfectant containing plants essential oil, it is characterised in that the disinfectant is PEI(10%),PHMB(20%), Made of Artemisia oil, plants essential oil, Tween 80, edible alcohol and deionized water.
2. a kind of long-acting bacteriostatic disinfectant containing plants essential oil according to claim 1, it is characterised in that plants essential oil is outstanding adds Sharp essential oil, tea tree ethereal oil, orange essential oil, dried orange peel essential oil, Rosa Damascana, lemon grass (Cymbopogon citratus) essential oil, Peppermint essential oil, thyme essential oil, fourth Essential oil, yulan flower essential oil, wormwood essential oil, Lavender, lemon or green tea essential oil.
3. a kind of long-acting bacteriostatic disinfectant containing plants essential oil according to claim 2, it is characterised in that the disinfectant is 3 parts ~ 6.4 parts of PEI(10%), 1.5 parts ~ 3.6 parts of PHMB(20%), 0.099 part ~ 0.186 part of Artemisia oil, 1.21 parts ~ 2.28 parts plants Object essential oil, 0.02 part ~ 0.35 part Tween 80,0.01 part ~ 68.5 part 95% edible alcohol and 309.17 parts ~ 990.37 parts go from Made of sub- water.
4. a kind of long-acting bacteriostatic disinfectant containing plants essential oil according to claim 2, it is characterised in that the disinfectant is By 5.4ml PEI(10%),2.5ml PHMB(20%), 0.125g Artemisia oils, 2.28g eucalyptus quintessence oils, 0.10ml Tween 80s, 68 Made of ml95% edible alcohols and 800ml deionized waters.
5. such as a kind of preparation method of long-acting bacteriostatic disinfectant containing plants essential oil of claim 1-4 any one, it is characterised in that The preparation method presses step progress:
By PEI under the conditions of 30 ~ 50 DEG C(10%)And PHMB(20%)Magnetic agitation 10 ~ 12 hours, be then completely dissolved in from In sub- water, Artemisia oil and plants essential oil are added, vibration of ultrasonic wave forms the micro- sol solution of milky in 1 ~ 5 minute;Then it is added and spits Temperature 80 enables solution be uniformly mixed using vortex agitator, adds 95% edible alcohol, and vibration of ultrasonic wave forms and stablizes for 1 ~ 3 minute Translucent solution;Obtain disinfectant.
CN201710226094.8A 2017-04-08 2017-04-08 A kind of long-acting bacteriostatic disinfectant containing plants essential oil and preparation method Withdrawn CN108684660A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110583702A (en) * 2019-09-18 2019-12-20 禹州市天源生物科技有限公司 Preparation method of tea tree essential oil disinfectant for animals
CN111264566A (en) * 2020-03-06 2020-06-12 吉林云飞医药有限公司 Household disinfectant and preparation method thereof
CN111418616A (en) * 2020-05-12 2020-07-17 杨冬 Environment-friendly efficient composite disinfectant and preparation method thereof
CN111543442A (en) * 2020-06-11 2020-08-18 杭州云昇科技有限公司 Composite sterilization liquid based on traditional Chinese medicine volatile oil and preparation method thereof
CN113057181A (en) * 2021-03-29 2021-07-02 安徽高梵电子商务有限公司 Soaking type disinfectant capable of removing peculiar smell of down feather

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CN105519597A (en) * 2016-01-11 2016-04-27 安佑生物科技集团股份有限公司 Animal barn air disinfectant containing plant essential oil, and application method thereof
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US20070042198A1 (en) * 2003-04-04 2007-02-22 Lars Schonemyr Antimicrobial substrate, a method and a composition for producing it
CN102793942A (en) * 2012-08-14 2012-11-28 合肥安森日化用品有限公司 Pure natural plant essential oil air freshener
CN106455553A (en) * 2014-09-19 2017-02-22 香港科技大学 Antimicrobial coating for long-term disinfection of surfaces
CN105519597A (en) * 2016-01-11 2016-04-27 安佑生物科技集团股份有限公司 Animal barn air disinfectant containing plant essential oil, and application method thereof

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110583702A (en) * 2019-09-18 2019-12-20 禹州市天源生物科技有限公司 Preparation method of tea tree essential oil disinfectant for animals
CN111264566A (en) * 2020-03-06 2020-06-12 吉林云飞医药有限公司 Household disinfectant and preparation method thereof
CN111418616A (en) * 2020-05-12 2020-07-17 杨冬 Environment-friendly efficient composite disinfectant and preparation method thereof
CN111543442A (en) * 2020-06-11 2020-08-18 杭州云昇科技有限公司 Composite sterilization liquid based on traditional Chinese medicine volatile oil and preparation method thereof
CN113057181A (en) * 2021-03-29 2021-07-02 安徽高梵电子商务有限公司 Soaking type disinfectant capable of removing peculiar smell of down feather

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Application publication date: 20181023