CN104398858A - Traditional Chinese medicine for treating diabetic heart disease - Google Patents

Traditional Chinese medicine for treating diabetic heart disease Download PDF

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CN104398858A
CN104398858A CN201410736427.8A CN201410736427A CN104398858A CN 104398858 A CN104398858 A CN 104398858A CN 201410736427 A CN201410736427 A CN 201410736427A CN 104398858 A CN104398858 A CN 104398858A
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chinese medicine
heart disease
traditional chinese
treating diabetic
diabetic heart
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唐芳刚
于朝霞
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    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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Abstract

The invention relates to the field of traditional Chinese medicine preparations and in particular to a traditional Chinese medicine for treating diabetic heart disease. The traditional Chinese medicine for treating diabetic heart disease is characterized by being prepared from the following medicine materials in percentage by weight: 12-16% of semen lepidii, 9-12% of allium macrostemon, 6-9% of polygonum cuspidatum, 5-9% of mesona blumes, 9-13% of gynostemma pentaphylla, 6-9% of blackend swallowwort root, 3-6% of fructus citri, 5-7% of rhizoma polygonati, 5-7% of sophora fruit, 3-5% of semen celosiae, 3-6% of radix ophiopogonis, 3-6% of myrrh, 3-6% of fructus psoraleae, 2-5% of cortex lycii radicis, 2-4% of hippophae rhamnoides and 3-5% of gastrodia elata. A method of the traditional Chinese medicine for treating diabetic heart disease comprises the following steps: soaking the sixteen kinds of medicine materials with water, decocting and then removing residues to obtain filtrate. The traditional Chinese medicine for treating diabetic heart disease has the benefits of being low in cost, high in curative effect of treating diabetic heart disease and free of toxic and side effects.

Description

Be used for the treatment of the Chinese medicine of diabetic cardiopathy
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine being used for the treatment of diabetic cardiopathy.
Background technology
As everyone knows, diabetic cardiopathy is the one of the main reasons that diabetics is lethal, especially in type 2 diabetes mellitus patient.The diabetic cardiopathy of broad sense comprises coronary atherosclerotic heart disease (coronary heart disease), diabetic cardiomyopathy and diabetic heart autonomic neuropathy etc.Diabetic cardiopathy compared with ND normal onset relatively early, diabetics companion coronary heart disease often shows as painless myocardial infarction, and infarct size is larger, it is many to wear wall infarction, and the state of an illness is many relatively seriously, and prognosis is poor, and case fatality rate is higher.
Diabetics accelerate atherosclerotic heart disease and myocardiac generation except hyperglycemia, mainly also often merge abnormalities of sugar/lipid metabolism with it, mortality of hypertension increase Abnormal Blood Rheology and insulin resistant or hyperinsulinemia etc. relevant.
At present, for the method that the treatment of diabetic cardiopathy is not effectively cured completely, modal method be exactly the Western medicine such as long-term taking atenolol to maintain the state of an illness, but long-term taking Western medicine, know from experience to people and bring larger side effect, and can not effect a radical cure.
Summary of the invention
Object of the present invention is exactly to overcome above-mentioned existing technical deficiency, provides a kind of Chinese medicine being used for the treatment of diabetic cardiopathy, this Chinese medicine preparation determined curative effect, cheap and have no side effect.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine being used for the treatment of diabetic cardiopathy, it is characterized in that being made up of following crude drug by weight percentage, Semen Lepidii (Semen Descurainiae) 12 ~ 16%, Bulbus Allii Macrostemonis 9 ~ 12%, Rhizoma Polygoni Cuspidati 6 ~ 9%, Herba mesonae chinensis 5 ~ 9%, Herb Gynostemmae Pentaphylli 9 ~ 13%, Radix Cynanchi Atrati 6 ~ 9%, Fructus Citri 3 ~ 6%, Rhizoma Polygonati 5 ~ 7%, Fructus Sophorae 5 ~ 7%, Semen Celosiae 3 ~ 5%, Radix Ophiopogonis 3 ~ 6%, Myrrha 3 ~ 6%, Fructus Psoraleae 3 ~ 6%, Cortex Lycii 2 ~ 5%, Fructus Hippophae 2 ~ 4%, Rhizoma Gastrodiae 3 ~ 5%, above-mentioned 16 taste crude drug are soaked, to remove slag after decocting to obtain filtrate.
The invention has the beneficial effects as follows, this Chinese medicine preparation determined curative effect, cheap and have no side effect.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
Semen Lepidii (Semen Descurainiae), Bulbus Allii Macrostemonis, Rhizoma Polygoni Cuspidati, Herba mesonae chinensis, Herb Gynostemmae Pentaphylli, Radix Cynanchi Atrati, Fructus Citri, Rhizoma Polygonati, Fructus Sophorae, Semen Celosiae, Radix Ophiopogonis, Myrrha, Fructus Psoraleae, Cortex Lycii, Fructus Hippophae, Rhizoma Gastrodiae is adopted to be that crude drug is prepared from.Its component (% by weight) is often paid as Semen Lepidii (Semen Descurainiae) 13.7, Bulbus Allii Macrostemonis 10.3, Rhizoma Polygoni Cuspidati 8.2, Herba mesonae chinensis 8.1, Herb Gynostemmae Pentaphylli 10.3, Radix Cynanchi Atrati 8.2, Fructus Citri 4.1, Rhizoma Polygonati 6.3, Fructus Sophorae 6.2, Semen Celosiae 4.1, Radix Ophiopogonis 3.9, Myrrha 4.1, Fructus Psoraleae 3.9, Cortex Lycii 3.4, Fructus Hippophae 2.1, Rhizoma Gastrodiae 3.1.Getting above-mentioned 16 taste raw material gross weights is 146 grams, and add water to 900 ~ 1000ml, water covers powder, soak 2 ~ 3 hours, make effective ingredient be easy to fried, then boil with high heat and slowly decoct about 40 minutes with slow fire again, remove slag to obtain filtrate about 150ml, medicinal residues add water 200 ~ 300ml again, and decoct 15 ~ 20 minutes, remove slag to obtain filtrate 50 ~ 70ml, be total to obtain about 200 ~ 220ml medicinal liquid, the i.e. decoction of obtained treatment diabetic cardiopathy, load in sterile glass vials, seal bottle cap is for subsequent use.Every day potion divide 2 times oral, each (medicine) being taken before meal 100 ~ 110ml.
Semen Lepidii (Semen Descurainiae) sputum of the present invention stops up the dyspnea and cough with excessive sputum of lung, lung abscess, edema, breast abdomen hydrops, dysuria, chronic pulmonary heart disease, and breathing heavily of heart failure is swollen; Bulbus Allii Macrostemonis cures mainly the thorough back of the body of obstruction of qi in the chest and cardialgia, and gastral cavity painful abdominal mass is not relaxed, and retches, heavy after dysentery; Rhizoma Polygoni Cuspidati dispels the wind, dampness removing, and removing blood stasis with potent drugs stimulates the menstrual flow.Dispelling the wind and dampness pathogens bones and muscles pain, arrhythmia and anti-cardiac muscle are lost blood; Herba mesonae chinensis clearing away summer-heat, quenches one's thirst, except pyretic toxicity.Control high blood, diabetes, heatstroke, quench one's thirst, hypertension, muscle, arthralgia; Herb Gynostemmae Pentaphylli can treat hypertension, hyperlipidemia, hyperglycemia, the diseases such as fatty liver; Radix Cynanchi Atrati clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment.For pathogenic warmth wound battalion heating, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, puerperal fever due to deficiency of blood; It is vexed that Fructus Citri cures mainly breast abdominal distention, distending pain over the hypochondrium, cough with copious phlegm; Rhizoma Polygonati boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying; Fructus Sophorae dispelling wind heat, lung moistening is dry, cool large intestine.Improving eyesight arresting lacrimation, teeth consolidating crow moustache, parasite killing; Semen Celosiae treating disorders in five ZANG-organs pathogen, beneficial brains, improve visual and auditory acuity, town liver, hard muscles and bones, removes anemofrigid-damp arthralgia; Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia; Raw property arthralgia controlled by Myrrha, sciatica, and oral cavity pain, has sore throat, cold cough, moist abundant expectoration, bronchiectasis; Fructus Psoraleae kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, lumbago due to renal deficiency, frequent micturition, bed-wetting, kidney leaks, warming spleen and stopping diarrha, helping inspiration to relieve asthma; Cortex Lycii has removing heat from blood except effects such as steaming, lung heat clearing pathogenic fire reducing; Cough-relieving sea-buckthorn eliminates the phlegm, relieving dyspepsia, promoting blood circulation to remove blood stasis.For cough with copious phlegm, dyspepsia, abdominal pain due to retention of food; Rhizoma Gastrodiae endogenous wind stopping, arresting convulsion.Control dizzy pupil, wind syndrome of head is had a headache, numb limbs and tense tendons, hemiplegia.The ingenious prescription of 16 taste Chinese herbal medicine, scientific compatibility: mutual reinforcement between, the mutual-assistance can play synergism, can improve drug effect; Mutual restraint between two drugs, the mutual-detoxication can alleviate or eliminate toxic and side effects, and the mutual coordinative role of medicine, plays the specially good effect of " diabetic cardiopathy " altogether.
The each raw material of the present invention also can the embodiment that mixes of ratio (percentage by weight) listed by according to the form below realize, and its processing method is identical with embodiment one.
The clinical trial carried out below in conjunction with my institute is done further the present invention, is described in detail:
1, case selection
Random selecting 42-68 year diabetic cardiopathy patient 100 example, its mean age is 57 years old, wherein, male 48 example, women 52 example.
2, Therapeutic Method
Every day 1 dose point 2 times is oral, and each (medicine) being taken before meal 100 ~ 110ml 7 days is a course for the treatment of, takes 6 courses for the treatment of altogether.
3, curative effect determinate standard
Effective: to strengthen by treating rear body constitution, with it energetically, feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating symptom such as to overrun obviously is alleviated, and the visible scheming blood supply of electrocardiogram improves; Effective: to strengthen by treating rear body constitution, with it energetically, feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating symptom such as to overrun is alleviated to some extent and is not healed; Invalid: after treatment, symptom is unchanged.
4, therapeutic outcome
At Clinical practice medicine of the present invention, take medicine 100 routine patients, take medicine after 3 courses for the treatment of, symptom is alleviated to some extent, and take medicine after 6 courses for the treatment of, symptom is obviously improved.In the routine patient of clinical trial 100, effective 75 examples, effective 22 examples, invalid 3 examples, total effective rate is 97%.
Model case
Normal certain, female, 53 years old, suffers from diabetes 4 years, and find diabetic cardiopathy half a year, cardiac insufficiency, atrial fibrillation, cardiopalmus is uncomfortable in chest, inability to breathe regularly due to shortness of breath, and dry pharynx, brings up phlegm when one coughs, fatigue and weak, edema of pair of lower extremities, dysuria.Once oral antidiabetic drug, blood glucose still controls bad, can't take care of oneself.Start to take Chinese medicine of the present invention through friend introduction, after 3 courses for the treatment of of taking medicine, the symptom such as uncomfortable in chest, to breathe hard obviously is improved, and after 6 courses for the treatment of of taking medicine, the visible blood supply of cardiac muscle of electrocardiogram also obviously improves on inspection, and the state of an illness is basicly stable, follows up a case by regular visits to after 1 year, and the state of an illness is without recurrence.
Zhang, man, 61 years old, suffer from diabetic cardiopathy 9 year, body constitution obviously dies down than before, and health is weak, often occur feeling of oppression and pain in the chest, palpitation and uneasiness, heart beating such as to be overrun at the symptom, after taking 4 courses for the treatment of of medicine of the present invention, above-mentioned symptom obviously improves, take medicine after 6 courses for the treatment of, energetically, the symptom such as feeling of oppression and pain in the chest, palpitation and uneasiness disappears health substantially, drug withdrawal was followed up a case by regular visits to after 1 year, and the state of an illness is without recurrence.

Claims (1)

1. one kind is used for the treatment of the Chinese medicine of diabetic cardiopathy, it is characterized in that being made up of following crude drug by weight percentage, Semen Lepidii (Semen Descurainiae) 12 ~ 16%, Bulbus Allii Macrostemonis 9 ~ 12%, Rhizoma Polygoni Cuspidati 6 ~ 9%, Herba mesonae chinensis 5 ~ 9%, Herb Gynostemmae Pentaphylli 9 ~ 13%, Radix Cynanchi Atrati 6 ~ 9%, Fructus Citri 3 ~ 6%, Rhizoma Polygonati 5 ~ 7%, Fructus Sophorae 5 ~ 7%, Semen Celosiae 3 ~ 5%, Radix Ophiopogonis 3 ~ 6%, Myrrha 3 ~ 6%, Fructus Psoraleae 3 ~ 6%, Cortex Lycii 2 ~ 5%, Fructus Hippophae 2 ~ 4%, Rhizoma Gastrodiae 3 ~ 5%, above-mentioned 16 taste crude drug are soaked, filtrate of removing slag after decocting to obtain.
CN201410736427.8A 2014-11-28 2014-11-28 Traditional Chinese medicine for treating diabetic heart disease Pending CN104398858A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106110203A (en) * 2016-08-02 2016-11-16 王昭霞 The Chinese medicine composition for the treatment of diabetic cardiopathy

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103127366A (en) * 2012-12-20 2013-06-05 刘登富 Chinese materia medica preparation for treating diabetic heart disease
WO2014077425A1 (en) * 2012-11-14 2014-05-22 한국한의학연구원 Pharmaceutical composition and functional health food containing paulownia extract for preventing or treating diabetes complications

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014077425A1 (en) * 2012-11-14 2014-05-22 한국한의학연구원 Pharmaceutical composition and functional health food containing paulownia extract for preventing or treating diabetes complications
CN103127366A (en) * 2012-12-20 2013-06-05 刘登富 Chinese materia medica preparation for treating diabetic heart disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106110203A (en) * 2016-08-02 2016-11-16 王昭霞 The Chinese medicine composition for the treatment of diabetic cardiopathy

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