CN104383049A - Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method thereof - Google Patents
Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method thereof Download PDFInfo
- Publication number
- CN104383049A CN104383049A CN201410728292.0A CN201410728292A CN104383049A CN 104383049 A CN104383049 A CN 104383049A CN 201410728292 A CN201410728292 A CN 201410728292A CN 104383049 A CN104383049 A CN 104383049A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- chinese medicine
- traditional chinese
- medicine formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/55—Linaceae (Flax family), e.g. Linum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine formula for treating severe acute pancreatitis and a preparation method thereof. The traditional Chinese medicine formula is prepared from the following traditional Chinese medicine raw materials in parts by weight: 5-8 parts of capillary wormwood herb, 5-8 parts of giant knotweed rhizome, 5-8 parts of rubus alceaefolius poir, 5-8 parts of Chinese thorowax root, 3-6 parts of tasteless preserved soybean, 3-6 parts of Wilson barberry root, 3-5 parts of white flower cacalia seed, 3-5 parts of longhairy antenoron herb, 3-6 parts of linseed, 3-6 parts of Chinese herbaceous peony, 3-8 parts of rheum officinale, 3-8 parts of mirabilite, 3-5 parts of salvia miltiorrhiza, 3-5 parts of cape jasmine fruit and 3-5 parts of kansui root. The preparation method comprises the step of preparing a water decoction. Because traditional Chinese medicines have the effects of regulating qi and alleviating mental depression, activating blood and dissolving stasis, and tonifying qi and supplementing yin, the traditional Chinese medicine formula disclosed by the invention can be used for reducing the pancreatic gland secretion, rapidly adjusting the self-inflammatory response, preventing endotoxin translocation, relieving the pain of patients and saving lives of the patients.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine formula for the treatment of Severe Acute Pancreatitis SAP and preparation method thereof.
Background technology
Acute pancreatitis causes pancreatic tissue autodigestion, edema, hemorrhage even downright bad inflammatory reaction after Different types of etiopathogenises causes pancreatin to be activated in pancreas.Clinically to increase etc. as feature with acute upper abdominal pain, Nausea and vomiting, heating and blood pancreatin.Not etc., the lighter is not based on pancreas edema, clinical common for lesion degree weight, and the state of an illness is often in self limiting, and prognosis bona, is also called mild acute pancreatitis.The pancreatic hemorrhage of minority severe one is downright bad, and normal secondary infection, peritonitis and shock etc., case fatality rate is high, is called Severe Acute Pancreatitis SAP.
The Severe Acute Pancreatitis SAP of 70% ~ 80% is caused by biliary tract, excessive drinking and eating and drinking too much at one meal, pathogenesis mainly pancreatic juice to the result of pancreas and surrounding tissue autodigestion thereof, interrelated and the cumulative function of inflammatory cytokine, causes the generation of the crisis such as vascular leakage, Hypovolemia, multiple system organ failure.The most most important link for the treatment of acute pancreatitis reduces pancreatic secretion, Chinese patent (CN103191322A) discloses a kind of Chinese medicine for the treatment of Severe Acute Pancreatitis SAP, by improve the anxious patient of serious symptom gastrointestinal function, suppress the secretion of Digestive system, suppress tryptic activity, thus alleviate pancreatic tissue inflammation
Disease, reduce the order of severity of the state of an illness, but Severe Acute Pancreatitis SAP rapid onset, development are swift and violent, need fast onset, contain PD rapidly, can the medicine of recuperating depleted YANG and rescuing the patient from collapse treat.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine formula for the treatment of Severe Acute Pancreatitis SAP, by the effect of the regulating the flow of QI to alleviate depression of Chinese medicine, blood circulation promoting and blood stasis dispelling, benefiting QI and recuperating YIN-fluid, pancreatic juice glandular secretion can be reduced, quick adjustment auto-inflammatory reacts, prevention Endotoxin Translocation, alleviates patient's misery, saves patients ' lives.
The invention provides a kind of Chinese medicine formula for the treatment of Severe Acute Pancreatitis SAP, formulated by the raw material of Chinese medicine of following parts by weight: Herba Artemisiae Scopariae 5 ~ 8 parts, Rhizoma Polygoni Cuspidati 5 ~ 8 parts, Radix seu Folium Rubi alceaefolii 5 ~ 8 parts, Radix Bupleuri 5 ~ 8 parts, tasteless preserved soybean 3 ~ 6 parts, little Radix Berberidis 3 ~ 6 parts, Semen Caesalpiniae Minacis 3 ~ 5 parts, Herba Lysimachiae 3 ~ 5 parts, Semen Lini 3 ~ 6 parts, Radix Paeoniae 3 ~ 6 parts, Radix Et Rhizoma Rhei 3 ~ 8 parts, 3 ~ 8 parts, Natrii Sulfas, Radix Salviae Miltiorrhizae 3 ~ 5 parts, Fructus Gardeniae 3 ~ 5 parts, Radix Kansui 3 ~ 5 parts.
More preferably formulated by the raw material of Chinese medicine of following parts by weight: Herba Artemisiae Scopariae 7 parts, Rhizoma Polygoni Cuspidati 6 parts, Radix seu Folium Rubi alceaefolii 6 parts, Radix Bupleuri 7 parts, tasteless preserved soybean 4 parts, little Radix Berberidis 4 parts, Semen Caesalpiniae Minacis 4 parts, Herba Lysimachiae 4 parts, Semen Lini 5 parts, Radix Paeoniae 5 parts, Radix Et Rhizoma Rhei 6 parts, 5 parts, Natrii Sulfas, Radix Salviae Miltiorrhizae 4 parts, Fructus Gardeniae 4 parts, Radix Kansui 4 parts.
Preparation method following steps form: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, do not have medical material 2 ~ 5cm, soak 1 ~ 2 hour; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 20 ~ 40min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
Pharmacology analysis:
Herba Artemisiae Scopariae: bitter, pungent, is slightly cold.Return spleen, stomach, liver, gallbladder meridian.Clearing away heat-damp and promoting diuresis; Jaundice eliminating.Cure mainly jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis etc.Pharmaceutical research has function of gallbladder promoting, liver function protecting, antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering, the effects such as coronary dilating.
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature; Return liver, gallbladder, lung meridian.Effect dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, relieving cough and resolving phlegm; For jaundice due to damp-heat, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, burn due to hot liquid or fire, amenorrhea, lump in the abdomen, instep plays damage, cough due to lung-heat.
Radix seu Folium Rubi alceaefolii: sweet light is flat.Function blood circulation promoting and blood stasis dispelling, clearing away heat to stop bleeding; Treating acute and chronic hepatitis, hepatosplenomegaly, march hemoglobinuria, mastitis, traumatic hemorrhage, stomatitis.
Radix Bupleuri: nature and flavor are bitter, are slightly cold.Return liver, gallbladder meridian.There is reconciling superficies and interior, soothing the liver, effect of yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.
Tasteless preserved soybean: bitter in the mouth, cold, nontoxic; Enter lung, stomach warp.Effect is induced sweat, relieving restlessness, Xuan Yu, removing toxic substances; Cure mainly typhoid fever calentura, cold and heat, headache, irritated, uncomfortable in chest.
Little Radix Berberidis: bitter, cold.Function heat-clearing and toxic substances removing, antiinflammatory, dysentery relieving; Cure mainly dysentery, sore, carbuncle and painful swelling, conjunctivitis, children's's oral erosion, enteritis, pneumonia, upper respiratory tract infection, acute binding film is scorching, mastitis, acute icterohepatitis, furuncle.
Semen Caesalpiniae Minacis: property bitter cold, has dissipating blood stasis, pain relieving, heat clearing away, the effect of drying.
Herba Lysimachiae: sweet in the mouth, micro-hardship, cool in nature; Return liver, gallbladder, kidney, urinary bladder channel.Effect relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling; Cure mainly liver and gall and urinary system calculus, pyretic stranguria, oedema due to nephritis, jaundice due to damp-heat, sore carbuncle, venom, traumatic injury.
Semen Lini: sweet in the mouth, tepor, nontoxic; Return lung, liver, large intestine channel.There are lubrication, abirritant effect, can be used for treating local inflammation.
Radix Paeoniae: Radix Paeoniae contains the multi-medicament such as peoniflorin and paeoniflorin composition, has the effect of blood vessel dilating, blood pressure lowering analgesia, heat clearing away spasmolytic, has higher medical value.
Radix Et Rhizoma Rhei: bitter in the mouth, cold; Return spleen, stomach, large intestine, liver, pericardium channel.Effect is attacked stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances; Cure mainly excess-heat constipation, the accumulation of heat feeling of stuffiness in chest, damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria, conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting, spits blood, spitting of blood, and epistaxis, has blood in stool, hematuria, blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, lump in the abdomen, traumatic injury, pyretic toxicity carbuncle and ulcer, erysipelas, scalds.
Natrii Sulfas: salty, bitter, cold; Return stomach warp, lung meridian, spleen channel, kidney channel, small intestine meridian, tri-jiao channel, large intestine channel.Function purging heat to relax the bowels, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat, cures mainly brokenly painful abdominal mass, in room temperature, helps digestion, relieves oedema or abdominal distension through diuresis or purgation, cathartic.For gastral cavilty painful abdominal mass, food painful abdominal mass, dyspepsia, edema, edema, swelling of the breast, amenorrhea, constipation.
Radix Salviae Miltiorrhizae: nature and flavor are bitter, are slightly cold; GUIXIN, Liver Channel.There is stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Fructus Gardeniae: heat clearing away, pathogenic fire purging, removing heat from blood; Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, haematemesis, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprain and swell and ache, there is the effects such as hepatoprotective, function of gallbladder promoting, blood pressure lowering, calmness, hemostasis, detumescence.
Radix Kansui: bitter in the mouth; Cold in nature, poisonous; Return spleen channel, lung meridian, kidney channel, urinary bladder channel, large intestine channel, small intestine meridian.Function removing water retention by purgation by swollen, dispersing swelling and dissipating binds; Cure mainly edema, ascites, prolonged fluid-retention blocked-up chest, epilepsy, breathes with cough, sphincter disturbance.
Chinese medicine of the present invention, by the effect of the regulating the flow of QI to alleviate depression of Chinese medicine, blood circulation promoting and blood stasis dispelling, benefiting QI and recuperating YIN-fluid, can reduce pancreatic juice glandular secretion, and quick adjustment auto-inflammatory reacts, and prevention Endotoxin Translocation, alleviates patient's misery, saves patients ' lives.
Outcome measure:
Effective: in 3 days, symptom, sign are alleviated, and in 7 days, blood, amylase in urine recover normal substantially.
Effective: in 7 days, symptom, sign alleviate, blood, amylase in urine have downward trend;
Invalid: in 7 days, symptom does not alleviate or worsens;
Therapeutic outcome: treat 129 severe acute pancreatitis 1st is 1 course for the treatment of, 1 day 2 doses.After taking medicine of the present invention, effective 62 examples, account for 48.1%, and effective 65 examples, account for 50.4%, and invalid 2 examples, account for 1.5%.
Attached several routine case is described further:
Case 1: grandson so-and-so, female, 52 years old, latter 1 hour upper abdomen center dull pain of taking food before 2 days, increase the weight of gradually, in persistence, to lower back radiation, lie on the back, cough or movable time increase the weight of, accompany low grade fever, feel sick, frequently vomit, spue food, gastric juice and bile, tells rear stomachache without alleviating, and repeatedly uses analgesic invalid.Result of having a medical check-up display T39 DEG C, P104 beat/min, R19 beat/min, Bp130/80mmHg, face of acute ill, curling position of lying on one's side, xerosis cutis, without petechia, superficial lymph knot does not touch, and sclera is without xanthochromia, and cardiopulmonary are without exception, and abdomen is smooth, epigastrium is slight muscle tonus, tenderness is obvious, suspicious rebound tenderness, do not touch lump, Murphy levies feminine gender, and Liver and kidney district is without obviously kowtowing pain, shifting dullness probable positive, borborygmus is slightly weak, two lower limb pneumonedema.Be diagnosed as acute critical pancreatitis, then give treatment by Chinese herbs of the present invention, effective after 3 days, inflammatory reaction is blocked, and after 7 days, blood, amylase in urine recover normal substantially.
Case 2: Hu, male, 60 years old, morbidity to break out tormina without obvious inducement the same day, from the beginning of to the right in ictal distending pain under chronognosis xiphoid-process, stomachache involves rapidly full abdominal part and changes into persistence, and the sample that lancinates has an intense pain, and to back radiation, companion's Nausea and vomiting, spue gastric content.Not defecation and aerofluxus since morbidity, and dare not stand up and also dare not deeply breathe, more dare not make abdominal part pressurized.Before 12 hours, stomachache increases the weight of and occurs dysphoria, and feel suffocated, companion body temperature rise emergency treatment then, disconnected disease is Severe Acute Pancreatitis SAP, then gives treatment by Chinese herbs of the present invention, and effective after 3 days, inflammatory reaction is blocked, and after 5 days, blood, amylase in urine recover normal substantially.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine formula for Severe Acute Pancreatitis SAP, formulated by the raw material of Chinese medicine of following parts by weight: Herba Artemisiae Scopariae 7 parts, Rhizoma Polygoni Cuspidati 6 parts, Radix seu Folium Rubi alceaefolii 6 parts, Radix Bupleuri 7 parts, tasteless preserved soybean 4 parts, little Radix Berberidis 4 parts, Semen Caesalpiniae Minacis 4 parts, Herba Lysimachiae 4 parts, Semen Lini 5 parts, Radix Paeoniae 5 parts, Radix Et Rhizoma Rhei 6 parts, 5 parts, Natrii Sulfas, Radix Salviae Miltiorrhizae 4 parts, Fructus Gardeniae 4 parts, Radix Kansui 4 parts.
Preparation method following steps form: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, do not have medical material 4cm, soak 1.5 hours; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 30min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
Embodiment 2:
Treat a Chinese medicine formula for Severe Acute Pancreatitis SAP, formulated by the raw material of Chinese medicine of following parts by weight: Herba Artemisiae Scopariae 5 parts, Rhizoma Polygoni Cuspidati 8 parts, Radix seu Folium Rubi alceaefolii 5 parts, Radix Bupleuri 8 parts, tasteless preserved soybean 3 parts, little Radix Berberidis 6 parts, Semen Caesalpiniae Minacis 3 parts, Herba Lysimachiae 5 parts, Semen Lini 3 parts, Radix Paeoniae 6 parts, Radix Et Rhizoma Rhei 3 parts, 8 parts, Natrii Sulfas, Radix Salviae Miltiorrhizae 3 parts, Fructus Gardeniae 5 parts, Radix Kansui 3 parts.
Preparation method following steps form: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, do not have medical material 2cm, soak 2 hours; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 20min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
Embodiment 3:
Treat a Chinese medicine formula for Severe Acute Pancreatitis SAP, formulated by the raw material of Chinese medicine of following parts by weight: Herba Artemisiae Scopariae 8 parts, Rhizoma Polygoni Cuspidati 5 parts, Radix seu Folium Rubi alceaefolii 8 parts, Radix Bupleuri 5 parts, tasteless preserved soybean 6 parts, little Radix Berberidis 3 parts, Semen Caesalpiniae Minacis 5 parts, Herba Lysimachiae 3 parts, Semen Lini 6 parts, Radix Paeoniae 3 parts, Radix Et Rhizoma Rhei 8 parts, 3 parts, Natrii Sulfas, Radix Salviae Miltiorrhizae 5 parts, Fructus Gardeniae 3 parts, Radix Kansui 5 parts.
Preparation method following steps form: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, do not have medical material 5cm, soak 1 hour; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 40min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.
Claims (3)
1. treat a Chinese medicine formula for Severe Acute Pancreatitis SAP, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Herba Artemisiae Scopariae 5 ~ 8 parts, Rhizoma Polygoni Cuspidati 5 ~ 8 parts, Radix seu Folium Rubi alceaefolii 5 ~ 8 parts, Radix Bupleuri 5 ~ 8 parts, tasteless preserved soybean 3 ~ 6 parts, little Radix Berberidis 3 ~ 6 parts, Semen Caesalpiniae Minacis 3 ~ 5 parts, Herba Lysimachiae 3 ~ 5 parts, Semen Lini 3 ~ 6 parts, Radix Paeoniae 3 ~ 6 parts, Radix Et Rhizoma Rhei 3 ~ 8 parts, 3 ~ 8 parts, Natrii Sulfas, Radix Salviae Miltiorrhizae 3 ~ 5 parts, Fructus Gardeniae 3 ~ 5 parts, Radix Kansui 3 ~ 5 parts.
2. a kind of Chinese medicine formula for the treatment of Severe Acute Pancreatitis SAP as claimed in claim 1, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Herba Artemisiae Scopariae 7 parts, Rhizoma Polygoni Cuspidati 6 parts, Radix seu Folium Rubi alceaefolii 6 parts, Radix Bupleuri 7 parts, tasteless preserved soybean 4 parts, little Radix Berberidis 4 parts, Semen Caesalpiniae Minacis 4 parts, Herba Lysimachiae 4 parts, Semen Lini 5 parts, Radix Paeoniae 5 parts, Radix Et Rhizoma Rhei 6 parts, 5 parts, Natrii Sulfas, Radix Salviae Miltiorrhizae 4 parts, Fructus Gardeniae 4 parts, Radix Kansui 4 parts.
3. the method for the Chinese medicine formula of preparation treatment as claimed in claim 1 Severe Acute Pancreatitis SAP, is characterized in that being made up of following steps: take raw material of Chinese medicine by above-mentioned weight portion, add cold water, there was not medical material 2 ~ 5cm, soak 1 ~ 2 hour; Then decoct, first boil with high heat, after boiling, transfer slow fire infusion 20 ~ 40min to; After cooked, leach medicine juice and decoct as head; Medicinal residues are repeated above-mentioned steps to decoct, after cooked, the medicine juice of twice decoction is merged.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410728292.0A CN104383049A (en) | 2014-12-03 | 2014-12-03 | Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410728292.0A CN104383049A (en) | 2014-12-03 | 2014-12-03 | Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104383049A true CN104383049A (en) | 2015-03-04 |
Family
ID=52601073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410728292.0A Pending CN104383049A (en) | 2014-12-03 | 2014-12-03 | Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104383049A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412373A (en) * | 2015-12-24 | 2016-03-23 | 范明月 | Traditional Chinese medicine for treating acute pancreatitis |
| CN105816685A (en) * | 2016-05-31 | 2016-08-03 | 徐秀堂 | Traditional Chinese medicine preparation for treating spleen and stomach heat type acute pancreatitis |
| CN105902916A (en) * | 2016-05-06 | 2016-08-31 | 张维霞 | Traditional Chinese medicine preparation for treating SAP (Severe Acute Pancreatitis) and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101385823A (en) * | 2008-10-23 | 2009-03-18 | 上海方心科技研究所 | Medicine for treating heavy acute pancreatitis and preparation method thereof |
| CN103463439A (en) * | 2013-08-19 | 2013-12-25 | 韩其厚 | Chinese herbal preparation for treating severe acute pancreatitis |
| CN103520351A (en) * | 2013-10-28 | 2014-01-22 | 孙立新 | Traditional Chinese medicine injection for treating severe acute pancreatitis and preparation method |
-
2014
- 2014-12-03 CN CN201410728292.0A patent/CN104383049A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101385823A (en) * | 2008-10-23 | 2009-03-18 | 上海方心科技研究所 | Medicine for treating heavy acute pancreatitis and preparation method thereof |
| CN103463439A (en) * | 2013-08-19 | 2013-12-25 | 韩其厚 | Chinese herbal preparation for treating severe acute pancreatitis |
| CN103520351A (en) * | 2013-10-28 | 2014-01-22 | 孙立新 | Traditional Chinese medicine injection for treating severe acute pancreatitis and preparation method |
Non-Patent Citations (3)
| Title |
|---|
| 刘殿青: "通腑清胆汤治疗急性胆胰病96例疗效观察", 《中国中医药科技》 * |
| 刘汉明: "大陷胸汤治疗急性胰腺炎1 例", 《河南中医》 * |
| 姜妙娜等: "急性实验性胰腺炎时胰腺组织学的变化及茵陈蒿汤的影响", 《中国中西医结合外科杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412373A (en) * | 2015-12-24 | 2016-03-23 | 范明月 | Traditional Chinese medicine for treating acute pancreatitis |
| CN105902916A (en) * | 2016-05-06 | 2016-08-31 | 张维霞 | Traditional Chinese medicine preparation for treating SAP (Severe Acute Pancreatitis) and preparation method thereof |
| CN105816685A (en) * | 2016-05-31 | 2016-08-03 | 徐秀堂 | Traditional Chinese medicine preparation for treating spleen and stomach heat type acute pancreatitis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102166317B (en) | Traditional Chinese medicine combination for curing metrorrhagia and metrostaxis | |
| CN103977358A (en) | Oral traditional Chinese medicine for lowering lipid and protecting liver | |
| CN104225441A (en) | Traditional Chinese medicine composition for treating stomach trouble and preparation method of granules and capsules of traditional Chinese medicine composition | |
| CN103816428B (en) | A kind of preparation of effective treatment diabetes | |
| CN101607011B (en) | Traditional Chinese medicine for treating cholecystitis post-operative complacation | |
| CN104383049A (en) | Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method thereof | |
| CN102847074B (en) | Blood stasis removing pill for treating ankylosing spondylitis | |
| CN104147536A (en) | Medicine composition for treating haemorrhoids and preparation method thereof | |
| CN104306929A (en) | Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method of traditional Chinese medicine formula | |
| CN103083616B (en) | Traditional Chinese medicine for treating ovarian cyst | |
| CN103212020A (en) | Traditional Chinese medicine composition for treating functional dyspepsia | |
| CN106267098A (en) | A kind of can effective Chinese medicine composition treating gout and preparation method thereof | |
| CN105727001A (en) | Traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases | |
| CN101780259B (en) | Traditional Chinese medicine for treating gastric cancer | |
| CN105727163A (en) | A traditional Chinese medicine formula for treating liver cancer and a preparing method thereof | |
| CN104338052A (en) | Formula of traditional Chinese medicine for treating cerebral thrombosis | |
| CN109939203A (en) | A kind of Chinese medicine and preparation method thereof for treating tumour | |
| CN109010779A (en) | A kind of traditional Chinese medicine lotion and its application method for treating hemorrhoid | |
| CN104306930A (en) | Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method of traditional Chinese medicine formula | |
| CN105726704A (en) | A traditional Chinese medicine formula for treating severe acute pancreatitis and a preparing method thereof | |
| CN105727215A (en) | Traditional Chinese medicinal prescription for treating severe acute pancreatitis and preparation method of traditional Chinese medicinal prescription | |
| CN105709005A (en) | Breast rehabilitation promoting pill | |
| CN101095919A (en) | Chinese patent drug for treating diabetes gallstone | |
| CN105727148A (en) | Drug for treating ascites due to cirrhosis and preparation thereof | |
| CN105311562A (en) | Traditional Chinese medicine for calming livers and reducing blood pressures |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150304 |
|
| RJ01 | Rejection of invention patent application after publication |