CN104382671A - 一种可有效防止移位、降低增生的可降解人体支架及制作方法 - Google Patents
一种可有效防止移位、降低增生的可降解人体支架及制作方法 Download PDFInfo
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Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106176001A (zh) * | 2016-06-29 | 2016-12-07 | 赵欣怡 | 一种防移位食道支架 |
CN106420127A (zh) * | 2016-10-15 | 2017-02-22 | 韩新巍 | 一种顺应食管蠕动性全贴合食管支架 |
CN109803590A (zh) * | 2016-10-10 | 2019-05-24 | 魏峥 | 具支架的血液导管 |
CN109984863A (zh) * | 2017-12-29 | 2019-07-09 | 先健科技(深圳)有限公司 | 双层血管支架 |
CN109984864A (zh) * | 2017-12-29 | 2019-07-09 | 先健科技(深圳)有限公司 | 用于分支血管的支架 |
WO2019196380A1 (zh) | 2018-04-12 | 2019-10-17 | 杭州糖吉医疗科技有限公司 | 胃导流器及其消化道支架、释放方法 |
CN112402078A (zh) * | 2020-11-05 | 2021-02-26 | 苏州法兰克曼医疗器械有限公司 | 一种防位移呼吸道支架 |
CN112972081A (zh) * | 2021-02-25 | 2021-06-18 | 南通大学附属医院 | 一种消化道可降解防移位支架及其制备方法 |
CN112972080A (zh) * | 2021-02-25 | 2021-06-18 | 南通大学附属医院 | 一种可生物降解的消化道堵漏支架及制备方法 |
CN113017914A (zh) * | 2021-03-17 | 2021-06-25 | 复旦大学附属中山医院 | 一种防止覆膜支架出入口内膜增生的外周血管复合支架 |
CN113520704A (zh) * | 2021-07-09 | 2021-10-22 | 乐普(北京)医疗器械股份有限公司 | 一种吻合口防瘘装置以及密封储存盒和装载器 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070219612A1 (en) * | 2006-03-20 | 2007-09-20 | Xtent, Inc. | Apparatus and methods for deployment of linked prosthetic segments |
US20070219613A1 (en) * | 2003-10-06 | 2007-09-20 | Xtent, Inc. | Apparatus and methods for interlocking stent segments |
CN102000366A (zh) * | 2010-12-08 | 2011-04-06 | 苏州同科生物材料有限公司 | 一种可降解自膨胀食管支架及其制备方法 |
US20110160836A1 (en) * | 2008-06-20 | 2011-06-30 | Vysera Biomedical Limited | Valve device |
CN202637199U (zh) * | 2012-05-07 | 2013-01-02 | 同济大学 | 一种螺旋形可降解食管支架 |
CN104095696A (zh) * | 2013-04-08 | 2014-10-15 | 上海市同济医院 | 用于食管破裂及吻合口漏封堵的食管内支架 |
-
2014
- 2014-09-11 CN CN201410462492.6A patent/CN104382671B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070219613A1 (en) * | 2003-10-06 | 2007-09-20 | Xtent, Inc. | Apparatus and methods for interlocking stent segments |
US20070219612A1 (en) * | 2006-03-20 | 2007-09-20 | Xtent, Inc. | Apparatus and methods for deployment of linked prosthetic segments |
US20110160836A1 (en) * | 2008-06-20 | 2011-06-30 | Vysera Biomedical Limited | Valve device |
CN102000366A (zh) * | 2010-12-08 | 2011-04-06 | 苏州同科生物材料有限公司 | 一种可降解自膨胀食管支架及其制备方法 |
CN202637199U (zh) * | 2012-05-07 | 2013-01-02 | 同济大学 | 一种螺旋形可降解食管支架 |
CN104095696A (zh) * | 2013-04-08 | 2014-10-15 | 上海市同济医院 | 用于食管破裂及吻合口漏封堵的食管内支架 |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106176001A (zh) * | 2016-06-29 | 2016-12-07 | 赵欣怡 | 一种防移位食道支架 |
CN109803590A (zh) * | 2016-10-10 | 2019-05-24 | 魏峥 | 具支架的血液导管 |
CN109803590B (zh) * | 2016-10-10 | 2021-10-29 | 魏峥 | 具支架的血液导管 |
CN106420127A (zh) * | 2016-10-15 | 2017-02-22 | 韩新巍 | 一种顺应食管蠕动性全贴合食管支架 |
CN106420127B (zh) * | 2016-10-15 | 2019-03-15 | 郑州大学第一附属医院 | 一种顺应食管蠕动性全贴合食管支架 |
CN109984864B (zh) * | 2017-12-29 | 2020-07-17 | 先健科技(深圳)有限公司 | 用于分支血管的支架 |
CN109984863B (zh) * | 2017-12-29 | 2020-04-07 | 先健科技(深圳)有限公司 | 双层血管支架 |
CN109984864A (zh) * | 2017-12-29 | 2019-07-09 | 先健科技(深圳)有限公司 | 用于分支血管的支架 |
US10993821B2 (en) | 2017-12-29 | 2021-05-04 | Lifetech Scientific (Shenzhen) Co., Ltd | Double-layer blood vessel stent |
CN109984863A (zh) * | 2017-12-29 | 2019-07-09 | 先健科技(深圳)有限公司 | 双层血管支架 |
WO2019196380A1 (zh) | 2018-04-12 | 2019-10-17 | 杭州糖吉医疗科技有限公司 | 胃导流器及其消化道支架、释放方法 |
CN112402078B (zh) * | 2020-11-05 | 2021-08-17 | 苏州法兰克曼医疗器械有限公司 | 一种防位移呼吸道支架 |
CN112402078A (zh) * | 2020-11-05 | 2021-02-26 | 苏州法兰克曼医疗器械有限公司 | 一种防位移呼吸道支架 |
CN112972080A (zh) * | 2021-02-25 | 2021-06-18 | 南通大学附属医院 | 一种可生物降解的消化道堵漏支架及制备方法 |
CN112972081A (zh) * | 2021-02-25 | 2021-06-18 | 南通大学附属医院 | 一种消化道可降解防移位支架及其制备方法 |
CN112972081B (zh) * | 2021-02-25 | 2022-11-25 | 南通大学附属医院 | 一种消化道可降解防移位支架及其制备方法 |
CN112972080B (zh) * | 2021-02-25 | 2022-11-25 | 南通大学附属医院 | 一种可生物降解的消化道堵漏支架及制备方法 |
CN113017914A (zh) * | 2021-03-17 | 2021-06-25 | 复旦大学附属中山医院 | 一种防止覆膜支架出入口内膜增生的外周血管复合支架 |
CN113520704A (zh) * | 2021-07-09 | 2021-10-22 | 乐普(北京)医疗器械股份有限公司 | 一种吻合口防瘘装置以及密封储存盒和装载器 |
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