CN104306934A - Medicine composition for enhancing immunity and preparation method thereof - Google Patents
Medicine composition for enhancing immunity and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine compound preparation, and discloses a medicine composition for enhancing immunity. The composition is prepared from the following components in parts by weight: 0.5-2 parts of cinnamon, 0.5-2 parts of dried ginger, 2-4.5 parts of schisandra chinensis, 2-4.5 parts of moutan bark, 2-4.5 parts of lophatherum gracile, 1.5-2.5 parts of semen ziziphi spinosae, 2-4.5 parts of radix rehmanniae, 2-4.5 parts of cornus officinalis, 0.5-2 parts of Chinese date and 2-4.5 parts of oyster. Clinical tests prove that the medicinal materials are synergized to play healthy functions of nourishing yin, tonifying yang, reinforcing qi, tranquilizing, clearing heat, relieving restlessness and enhancing immunity. The invention further discloses a method for preparing the medicine composition for enhancing immunity. The method is simple in operation, environment-friendly, economical, efficient and non-toxic, and has a wide application prospect.
Description
Technical field
The present invention relates to Chinese medicine compound and control agent, relate to a kind of pharmaceutical composition with enhancing immunity, particularly relate to the preparation method of the pharmaceutical composition with enhancing immunity.
Background technology
Immunity is the defense mechanism of human body self, is human bioequivalence and any foreign body (virus, antibacterial etc.) eliminating external intrusion; Process is old and feeble, damage, the ability of mutant cell and virus infected cell in the own cells of dead, degeneration and identification and handling body.Immunology Today is thought, immunity is the physiological reaction of human bioequivalence and eliminating " dissident ".What perform this function in human body is immune system.Over millions of year, the mankind were not only applicable to existence but also the environment be fraught with risks life one, and the mankind are able to survival, also obtain outstanding immunity.Immunity is the product of biological evolution process thus.
The health of hypoimmunity is easy to infected or cancer stricken; Immunity is extraordinary also can produce insalubrious result, as caused anaphylaxis, autoimmune disease etc.A variety of causes makes immune system normally can not play protective effect, and in the case, very easily cause the infection such as antibacterial, virus, fungus, therefore hypoimmunity the most directly shows is exactly liable to illness.Because of often ill, increased the weight of the consumption of body, thus generally have a delicate constitution, the reduction of malnutrition, lethargy, fatigue and weak, appetite, the performance such as sleep disorder, sick, have an injection and take medicine the normal potluck that just gets married.At every turn sickly all to could to recover for a long time, and usually recurrent exerbation.If things go on like this can cause health and intelligent development bad, also easily bring out major disease.Underlying causes is that hypoimmunity or immunity are unsound.When immune function of human body imbalance, or when immune system is unsound, following point will recurrent exerbation flu recurrent exerbation, tonsillitis recurrent exerbation, asthma recurrent exerbation, bronchitis recurrent exerbation, pneumonia recurrent exerbation, diarrhoea recurrent exerbation, so necessarily can't neglect.
Have huge harm based on hypoimmunity, therefore, strengthen the food of body immunity or medicine, be one of the study hotspot field of medical personal in this year always.
Summary of the invention
The present invention is directed to the shortcoming of prior art, disclose a kind of pharmaceutical composition with enhancing immunity, also disclose the preparation method of the pharmaceutical composition with enhancing immunity; Easy to prepare, condition is simple, safe and reliable, be applicable to suitability for industrialized production.
In order to solve the problems of the technologies described above, the present invention is solved by following technical proposals.
Have a pharmaceutical composition for enhancing immunity, in following weight proportion, each component and content are, 0.5-2 part Cortex Cinnamomi, 0.5-2 part Rhizoma Zingiberis, 2-4.5 part Fructus Schisandrae Chinensis, 2-4.5 part Cortex Moutan, 2-4.5 part Herba Lophatheri, 1.5-2.5 part Semen Ziziphi Spinosae, 2-4.5 part Radix Rehmanniae, 2-4.5 part Fructus Corni, 0.5-2 part Fructus Jujubae, 2-4.5 part Concha Ostreae.
The present invention has nourishing YIN and invigorating YANG, invigorating QI and tranquilization, clearing heat and relieving fidgetness, the health care of enhancing immunity.
Cortex Cinnamomi, pungent, sweet, hot greatly.Return kidney, spleen, the heart, Liver Channel.It is supporing yang that function mends fire, guiding fire to origin, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian.
Rhizoma Zingiberis, pungent, heat.Return spleen, stomach, kidney, the heart, lung meridian.Function warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, warming the lung to resolve fluid-retention.
Fructus Schisandrae Chinensis, sour, sweet, warm.Woman's lung, the heart, kidney channel.Function convergence is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.
Cortex Moutan is bitter, pungent, be slightly cold.GUIXIN, liver, kidney channel.Function clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.
Herba Lophatheri, sweet, light, cold.GUIXIN, stomach, small intestine meridian.Function clearing away heat-fire, relieving restlessness is quenched the thirst, inducing diuresis for treating stranguria syndrome.
Semen Ziziphi Spinosae is sweet, sour, flat.Return liver, gallbladder, heart channel.Function nourishes heart tonifying liver, and mind tranquilizing and the heart calming, arresting sweating, promotes the production of body fluid.
Radix Rehmanniae, sweet, cold.GUIXIN, liver, kidney channel.Function clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.
Fructus Corni, sour, puckery, tepor.Return liver, kidney channel.Function liver and kidney tonifying, arresting collape syndrome by astringents.
Fructus Jujubae, sweet, warm.Return spleen, stomach, heart channel.Function invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.
Concha Ostreae is salty, be slightly cold.Return liver, gallbladder, kidney channel.Function tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.
As preferably, in following weight proportion, each component and content are, 0.5-1.5 part Cortex Cinnamomi, 0.5-1.5 part Rhizoma Zingiberis, 2-3.5 part Fructus Schisandrae Chinensis, 2-3.5 part Cortex Moutan, 2-3.5 part Herba Lophatheri, 1.5-2.3 part Semen Ziziphi Spinosae, 2-3.5 part Radix Rehmanniae, 2-3.5 part Fructus Corni, 0.5-1.5 part Fructus Jujubae, 2-3.5 part Concha Ostreae.The pharmaceutical composition with enhancing immunity of the raw material formation of this proportioning, safety is high, and the effect of enhancing immunity is ideal.
As preferably, in following weight proportion, each component and content is, 1 portion of Cortex Cinnamomi, 1 portion of Rhizoma Zingiberis, 3 parts of Fructus Schisandrae Chinensis, 3 parts of Cortex Moutans, 3 portions of Herba Lophatheris, 2 parts of Semen Ziziphi Spinosaes, 3 portions of Radix Rehmanniae, 3 parts of Fructus Corni, 1 portion of Fructus Jujubae, 3 portions of Concha Ostreaes.The pharmaceutical composition with enhancing immunity of the raw material formation of this proportioning, safety is high, and the effect of enhancing immunity is even more ideal.
As preferably, the pharmaceutical composition of the treatment climacteric syndrome of every 23 grams comprises following component: 1g Cortex Cinnamomi, 1g Rhizoma Zingiberis, 3g Fructus Schisandrae Chinensis, 3g Cortex Moutan, 3g Herba Lophatheri, 2g Semen Ziziphi Spinosae, 3g Radix Rehmanniae, 3g Fructus Corni, 1g Fructus Jujubae, 3g Concha Ostreae.The pharmaceutical composition with enhancing immunity of the raw material formation of this proportioning, safety is high, the best results of enhancing immunity.
As preferably, the pharmaceutical composition with enhancing immunity makes oral liquid or tablet or capsule or pill or granule or drop pill.
The above-described preparation method with the pharmaceutical composition of enhancing immunity, comprises the following steps,
A. above medical material decocts with water, and adds 7-10 ml water in every 1 gram of medical material, decocts 3 times, and first time decocts 1.5-3h, and second time decocts 1-2h, and third time decocts 0.5-1.5h; Add 7-10 ml water in every 1 gram of medical material, the effect that during decoction, Chinese medicine ingredients is dissolved in water is better.When decocting 3 times, more desirable to the effect of Chinese medicine constituents extraction.
B. merge three decoctions and filter the filtrate obtained afterwards, filtrate is concentrated into the extractum that relative density is 1.20-1.25;
C. adding ethanol to alcohol precipitation concentration is 50-80%, and leave standstill 24h, getting supernatant concentration to relative density is the extractum of 1.12-1.20, dry, obtains the pharmaceutical composition with enhancing immunity.Chinese medicine water drug-decocting concentrating liquid, removes the starch, protein etc. of non-prolamine, adds the liquid that ethanol is made into certain alcoholic degree, then room temperature preferably freezing sedimentation carry out solid-liquid separation to improve alcoholic degree and the clarity of Chinese medicine extraction liquid, thus to improve the quality of products.
As preferably, step D, adds starch, mixes, incapsulate with the pharmaceutical composition with enhancing immunity.
As preferably, in step B, after merging filtrate, at 60 DEG C, filtrate is concentrated into the extractum that relative density is 1.20-1.25.
As preferably, in step C, at 60 DEG C, be the extractum of 1.12-1.20 by supernatant concentration to relative density, spraying dry, obtains the pharmaceutical composition with enhancing immunity.
Compared with prior art, beneficial effect of the present invention is:
The pharmaceutical composition with enhancing immunity that the present invention is Cortex Cinnamomi, Rhizoma Zingiberis, Fructus Schisandrae Chinensis, Cortex Moutan, Herba Lophatheri, Semen Ziziphi Spinosae, Radix Rehmanniae, Fructus Corni, Fructus Jujubae, Concha Ostreae obtain.Find through clinical trial, above medical material synergism, has following effect: nourishing YIN and invigorating YANG, invigorating QI and tranquilization, clearing heat and relieving fidgetness, the health care of enhancing immunity.
Preparation method of the present invention, simple to operate, environmental protection, economy, efficient, nontoxic, have broad application prospects.
Detailed description of the invention
Embodiment 1
Have a pharmaceutical composition for enhancing immunity, in following weight proportion, each component and content is, 0.5 portion of Cortex Cinnamomi, 0.5 portion of Rhizoma Zingiberis, 2 parts of Fructus Schisandrae Chinensis, 2 parts of Cortex Moutans, 2 portions of Herba Lophatheris, 1.5 parts of Semen Ziziphi Spinosaes, 2 portions of Radix Rehmanniae, 2 parts of Fructus Corni, 0.5 portion of Fructus Jujubae, 2 portions of Concha Ostreaes.The pharmaceutical composition with enhancing immunity makes oral liquid.
The above-described preparation method with the pharmaceutical composition of enhancing immunity, comprises the following steps,
A. above medical material decocts with water, and adds 7 ml waters in every 1 gram of medical material, decocts 3 times, and first time decocts 1.5h, and second time decocts 1h, and third time decocts 0.5h;
B. merge three decoctions and filter the filtrate obtained afterwards, filtrate is concentrated into the extractum that relative density is 1.20;
C. adding ethanol to alcohol precipitation concentration is 50%, and leave standstill 24h, getting supernatant concentration to relative density is the extractum of 1.12, obtains the pharmaceutical composition with enhancing immunity.
Embodiment 2
Have a pharmaceutical composition for enhancing immunity, in following weight proportion, each component and content is, 2 portions of Cortex Cinnamomis, 2 portions of Rhizoma Zingiberiss, 4.5 parts of Fructus Schisandrae Chinensis, 4.5 parts of Cortex Moutans, 4.5 portions of Herba Lophatheris, 2.5 parts of Semen Ziziphi Spinosaes, 4.5 portions of Radix Rehmanniae, 4.5 parts of Fructus Corni, 2 portions of Fructus Jujubaes, 4.5 portions of Concha Ostreaes.The pharmaceutical composition with enhancing immunity makes tablet.
The above-described preparation method with the pharmaceutical composition of enhancing immunity, comprises the following steps,
A. above medical material decocts with water, and adds 10 ml waters in every 1 gram of medical material, decocts 3 times, and first time decocts 3h, and second time decocts 2h, and third time decocts 1.5h;
B. merge three decoctions and filter the filtrate obtained afterwards, filtrate is concentrated into the extractum that relative density is 1.25;
C. adding ethanol to alcohol precipitation concentration is 80%, and leave standstill 24h, getting supernatant concentration to relative density is the extractum of 1.20, dry, obtains the pharmaceutical composition with enhancing immunity.
Embodiment 3
Have a pharmaceutical composition for enhancing immunity, in following weight proportion, each component and content is, 1.5 portions of Cortex Cinnamomis, 1.5 portions of Rhizoma Zingiberiss, 3.5 parts of Fructus Schisandrae Chinensis, 3.5 parts of Cortex Moutans, 3.5 portions of Herba Lophatheris, 2.3 parts of Semen Ziziphi Spinosaes, 3.5 portions of Radix Rehmanniae, 3.5 parts of Fructus Corni, 1.5 portions of Fructus Jujubaes, 3.5 portions of Concha Ostreaes.
The pharmaceutical composition with enhancing immunity makes capsule.
The above-described preparation method with the pharmaceutical composition of enhancing immunity, comprises the following steps,
A. above medical material decocts with water, and adds 8 ml waters in every 1 gram of medical material, decocts 3 times, and first time decocts 1.8h, and second time decocts 1.5h, and third time decocts 0.8h;
B. merge three decoctions and filter the filtrate obtained afterwards, filtrate is concentrated into the extractum that relative density is 1.21;
C. adding ethanol to alcohol precipitation concentration is 55%, and leave standstill 24h, getting supernatant concentration to relative density is the extractum of 1.18, dry, obtains the pharmaceutical composition with enhancing immunity;
D. add starch, mix with the pharmaceutical composition with enhancing immunity, incapsulate.
Embodiment 4
Have a pharmaceutical composition for enhancing immunity, in following weight proportion, each component and content is, 1 portion of Cortex Cinnamomi, 1 portion of Rhizoma Zingiberis, 3 parts of Fructus Schisandrae Chinensis, 3 parts of Cortex Moutans, 3 portions of Herba Lophatheris, 2 parts of Semen Ziziphi Spinosaes, 3 portions of Radix Rehmanniae, 3 parts of Fructus Corni, 1 portion of Fructus Jujubae, 3 portions of Concha Ostreaes.The pharmaceutical composition with enhancing immunity makes pill.
The above-described preparation method with the pharmaceutical composition of enhancing immunity, comprises the following steps,
A. above medical material decocts with water, and adds 8 ml waters in every 1 gram of medical material, decocts 3 times, and first time decocts 2.8h, and second time decocts 1.8h, and third time decocts 1.3h;
B. merge three decoctions and filter the filtrate obtained afterwards, after merging filtrate, at 60 DEG C, filtrate is concentrated into the extractum that relative density is 1.24;
C. adding ethanol to alcohol precipitation concentration is 78%, and leave standstill 24h, at 60 DEG C, be the extractum of 1.19 by supernatant concentration to relative density, pill, obtains the pharmaceutical composition with enhancing immunity.
Embodiment 5
Have a pharmaceutical composition for enhancing immunity, the pharmaceutical composition of the treatment climacteric syndrome of every 23 grams comprises following component: 1g Cortex Cinnamomi, 1g Rhizoma Zingiberis, 3g Fructus Schisandrae Chinensis, 3g Cortex Moutan, 3g Herba Lophatheri, 2g Semen Ziziphi Spinosae, 3g Radix Rehmanniae, 3g Fructus Corni, 1g Fructus Jujubae, 3g Concha Ostreae.The pharmaceutical composition with enhancing immunity makes granule.
The above-described preparation method with the pharmaceutical composition of enhancing immunity, comprises the following steps,
A. above medical material decocts with water, and adds 8 ml waters in every 1 gram of medical material, decocts 3 times, and first time decocts 1.6h, and second time decocts 1.1h, and third time decocts 0.6h;
B. merge three decoctions and filter the filtrate obtained afterwards, filtrate is concentrated into the extractum that relative density is 1.21;
C. adding ethanol to alcohol precipitation concentration is 51%, and leave standstill 24h, getting supernatant concentration to relative density is the extractum of 1.13, granulates, obtains the pharmaceutical composition with enhancing immunity.
Embodiment 6
Have a pharmaceutical composition for enhancing immunity, the pharmaceutical composition of the treatment climacteric syndrome of every 23 grams comprises following component: 1g Cortex Cinnamomi, 1g Rhizoma Zingiberis, 3g Fructus Schisandrae Chinensis, 3g Cortex Moutan, 3g Herba Lophatheri, 2g Semen Ziziphi Spinosae, 3g Radix Rehmanniae, 3g Fructus Corni, 1g Fructus Jujubae, 3g Concha Ostreae.
The pharmaceutical composition with enhancing immunity makes drop pill.
The above-described preparation method with the pharmaceutical composition of enhancing immunity, comprises the following steps,
A. above medical material decocts with water, and adds 8 ml waters in every 1 gram of medical material, decocts 3 times, and first time decocts 1.6h, and second time decocts 1.1h, and third time decocts 0.6h;
B. merge three decoctions and filter the filtrate obtained afterwards, filtrate is concentrated into the extractum that relative density is 1.21;
C. adding ethanol to alcohol precipitation concentration is 51%, and leave standstill 24h, getting supernatant concentration to relative density is the extractum of 1.13, and pill, obtains the pharmaceutical composition with enhancing immunity.
Embodiment 7
This experiment, by the research with the pharmaceutical composition of enhancing immunity mentioned in embodiment 6, understands the effect that it improves immunity.
One, experiment material
1. Experimental agents: improve immunity drug extract and be divided into three dosage groups (high dose group, middle dosage group, low dose group) administration, be respectively 6g/kg, 3g/kg, 1.5g/kg; With meat soup, the Radix Astragali as a control group.
2. instrument: biological microscope is that Japan produces OLYMPLUS.
3. animal: Kunming mouse, body weight 27.0 ± 2.0g, is provided by animal experimental center.
Two, experimental technique and result
Get mice 45, be divided into 5 groups at random, grouping and administration are in table 1, and administration capacity is 0.2ml/10g.Once a day, totally 7 times, meat soup matched group every day is to normal saline.24h before last administration, each group mice equal lumbar injection 6% starch Broth solution 1ml/ only.During experiment aseptically, get Sanguis Gallus domesticus with brine 3 times, be made into 5%RBC-NS suspension, and only give every mouse peritoneal injection 1ml, 0.5h pneumoretroperitoneum injecting normal saline 2ml/, rub the abdominal part that rubs, put to death and open abdomen and get ascites.Ascites is centrifugal, taking precipitate smear, every Mus is coated with 3, place airing, Wright dyes, counting 100 macrophages (M Φ) under every sheet oil mirror, therefrom counts the M Φ number of having engulfed chicken RBC and by chicken red blood cell (CRBC) sum engulfed, and obtain average phagocytic rate and the phagocytic index of every Mus, the results are shown in Table 1.
Table 1 improves immunity extract engulfs chicken RBC vigor impact (X ± SD) on Turnover of Mouse Peritoneal Macrophages
| Group | Dosage (g/kg/ day) | n | Phagocytic rate % | Phagocytic index |
| Meat soup contrasts | - | 8 | 35.5±5.29 | 2.06±0.22 |
| Low dose group | 1.5 | 9 | 58.0±7.28 ＊ | 2.81±0.25 ＊ |
| Middle dosage group | 3.0 | 9 | 64.1±3.14 ＊ | 2.89±0.35 ＊ |
| High dose group | 6.0 | 9 | 67.8±2.86 ＊ | 2.63±0.07 ＊ |
| The Radix Astragali contrasts | 20.0 | 9 | 52.4±3.75 ＊ | 3.41±0.25 ＊ |
Note: compared with meat soup matched group
*p<0.01
Test each dosage group of extract used and all significantly can increase the ability that Turnover of Mouse Peritoneal Macrophages engulfs chicken RBC, show that it has nonspecific immunity promotion functions.
In a word, the foregoing is only preferred embodiment of the present invention, all equalizations done according to the present patent application the scope of the claims change and modify, and all should belong to the covering scope of patent of the present invention.
Claims (9)
1. have a pharmaceutical composition for enhancing immunity, it is characterized in that: in following weight proportion, each component and content are, 0.5-2 part Cortex Cinnamomi, 0.5-2 part Rhizoma Zingiberis, 2-4.5 part Fructus Schisandrae Chinensis, 2-4.5 part Cortex Moutan, 2-4.5 part Herba Lophatheri, 1.5-2.5 part Semen Ziziphi Spinosae, 2-4.5 part Radix Rehmanniae, 2-4.5 part Fructus Corni, 0.5-2 part Fructus Jujubae, 2-4.5 part Concha Ostreae.
2. the pharmaceutical composition with enhancing immunity according to claim 1, is characterized in that: in following weight proportion, each component and content are, 0.5-1.5 part Cortex Cinnamomi, 0.5-1.5 part Rhizoma Zingiberis, 2-3.5 part Fructus Schisandrae Chinensis, 2-3.5 part Cortex Moutan, 2-3.5 part Herba Lophatheri, 1.5-2.3 part Semen Ziziphi Spinosae, 2-3.5 part Radix Rehmanniae, 2-3.5 part Fructus Corni, 0.5-1.5 part Fructus Jujubae, 2-3.5 part Concha Ostreae.
3. the pharmaceutical composition with enhancing immunity according to claim 1, is characterized in that: in following weight proportion, each component and content are, 1 portion of Cortex Cinnamomi, 1 portion of Rhizoma Zingiberis, 3 parts of Fructus Schisandrae Chinensis, 3 parts of Cortex Moutans, 3 portions of Herba Lophatheris, 2 parts of Semen Ziziphi Spinosaes, 3 portions of Radix Rehmanniae, 3 parts of Fructus Corni, 1 portion of Fructus Jujubae, 3 portions of Concha Ostreaes.
4. the pharmaceutical composition with enhancing immunity according to claim 1, it is characterized in that: the pharmaceutical composition of the treatment climacteric syndrome of every 23 grams comprises following component: 1g Cortex Cinnamomi, 1g Rhizoma Zingiberis, 3g Fructus Schisandrae Chinensis, 3g Cortex Moutan, 3g Herba Lophatheri, 2g Semen Ziziphi Spinosae, 3g Radix Rehmanniae, 3g Fructus Corni, 1g Fructus Jujubae, 3g Concha Ostreae.
5. the pharmaceutical composition with enhancing immunity according to claim 1 or 2 or 3 or 4, is characterized in that: the pharmaceutical composition with enhancing immunity makes oral liquid or tablet or capsule or pill or granule or drop pill.
6. claim 1 or the preparation method with the pharmaceutical composition of enhancing immunity described in 2 or 3 or 4, is characterized in that: comprise the following steps,
A. above medical material decocts with water, and adds 7-10 ml water in every 1 gram of medical material, decocts 3 times, and first time decocts 1.5-3h, and second time decocts 1-2h, and third time decocts 0.5-1.5h;
B. merge three decoctions and filter the filtrate obtained afterwards, filtrate is concentrated into the extractum that relative density is 1.20-1.25;
C. adding ethanol to alcohol precipitation concentration is 50-80%, and leave standstill 24h, getting supernatant concentration to relative density is the extractum of 1.12-1.20, dry, obtains the pharmaceutical composition with enhancing immunity.
7. the preparation method with the pharmaceutical composition of enhancing immunity according to claim 6, is characterized in that: step D, adds starch, mixes, incapsulate with the pharmaceutical composition with enhancing immunity.
8. the preparation method with the pharmaceutical composition of enhancing immunity according to claim 6, is characterized in that: in step B, after merging filtrate, at 60 DEG C, filtrate is concentrated into the extractum that relative density is 1.20-1.25.
9. the preparation method with the pharmaceutical composition of enhancing immunity according to claim 6, it is characterized in that: in step C, at 60 DEG C, is the extractum of 1.12-1.20 by supernatant concentration to relative density, spraying dry, obtains the pharmaceutical composition with enhancing immunity.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104721620A (en) * | 2015-03-18 | 2015-06-24 | 苏州普罗达生物科技有限公司 | Leafy composition for enhancing immunity |
| WO2016197878A1 (en) * | 2015-06-10 | 2016-12-15 | Thisherb Health Pty Ltd | Pharmaceutical composition for treatment of menopausal syndrome and preparation method thereof |
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| CN102551155A (en) * | 2011-12-31 | 2012-07-11 | 上海豪源生物制品有限公司 | Diet drink and preparing method thereof |
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| CN102551155A (en) * | 2011-12-31 | 2012-07-11 | 上海豪源生物制品有限公司 | Diet drink and preparing method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104721620A (en) * | 2015-03-18 | 2015-06-24 | 苏州普罗达生物科技有限公司 | Leafy composition for enhancing immunity |
| WO2016197878A1 (en) * | 2015-06-10 | 2016-12-15 | Thisherb Health Pty Ltd | Pharmaceutical composition for treatment of menopausal syndrome and preparation method thereof |
| GB2554010A (en) * | 2015-06-10 | 2018-03-21 | Thisherb Health Pty Ltd | Pharmaceutical composition for treatment of menopausal syndrome and preparation method thereof |
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