CN101683429A - Animal Chinese medicine granular formulation for preventing and treating infectious bursal disease of fowl and preparation method thereof - Google Patents
Animal Chinese medicine granular formulation for preventing and treating infectious bursal disease of fowl and preparation method thereof Download PDFInfo
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- CN101683429A CN101683429A CN200810151753A CN200810151753A CN101683429A CN 101683429 A CN101683429 A CN 101683429A CN 200810151753 A CN200810151753 A CN 200810151753A CN 200810151753 A CN200810151753 A CN 200810151753A CN 101683429 A CN101683429 A CN 101683429A
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Abstract
The invention relates to a animal Chinese medicine granular formulation for preventing and treating infectious bursal disease of fowl and a preparation method thereof, which is characterized in that:the medicament contains the following medicaments: gypsum 1-8 parts by weight, isatis root 1-8 parts by weight, astragalus 1-5 parts by weight, dried rehmannia root 1-3 parts by weight, root bark of tree peony 1-3 parts by weight, and liquorice 1-5 parts by weight; the preparation method includes the steps of: weighing the medicaments as raw materials in parts by weight; adding water into the Chinese medicine for decocting Chinese medicine twice, decocting Chinese medicine for 1.5 hour every time, combining decoction liquids of the two times, filtering, concentrating filter liquor to clear paste with relative density of 1.08, when the clear paste is cooled to room temperature, adding equivalent ethanol for precipitation, standing for 30 minutes, concentrating supernatant into thick paste with relative density of 1.38-1.40, adding appropriate amount of sucrose and saccharine, mixing evenly and sponge drying. The invention can overcome that vaccine, highly immunized egg yolk antibody andother Chinese medicament preparations have insufficiencies in preventing and treating infectious bursal disease of fowl without any medicament residuals for organism and any toxic and side effects, and the invention can be used conveniently.
Description
Technical field
The invention belongs to fowl and use Chinese medicine, relate in particular to a kind of herbal medicine granule of preventing and treating poultry infectious bursal disease and preparation method thereof.
Background technology
Poultry infectious bursal disease is a kind of immune maincenter organ with the destruction poultry that is caused by infectious bursal disease virus---fabricius bursa is acute, the height contagious disease of feature.Because after poultry infects infectious bursal disease virus, the immune maincenter organ of poultry is destroyed, the result causes serious immunosuppressant, on the one hand body is weakened to the responsing reaction of various vaccines, influence the epidemic prevention effect of vaccine, the premunition of poultry itself is weakened, the various infectious disease of easier trouble.At present vaccine is mainly used in the prevention of primary disease, vaccine has two kinds of the vaccine of mesogenic and weak virulence vaccines.Though the vaccine of mesogenic has the good preventing effect to primary disease, the vaccine of mesogenic destroys the fabricius bursa of fowl easily, and poultry is reduced the resistance of other diseases.Though the vaccine of weak virulence does not have destruction to the fabricius bursa of fowl, immune effect is relatively poor.Medicine to primary disease mainly contains fabricius bursa high immunity yolk antibody, Chinese medicine preparation.The fabricius bursa high immunity yolk antibody is easy to be polluted in the process of producing, and to produce the used fowl egg of high immunity yolk antibody scarcely be that the poultry of specific pathogen free microorganism produces, so the very difficult pathogenic microorganism that do not carry in the high immunity yolk antibody.The Chinese medicine preparation major part is a powder, the medicine mixing must be used in feedstuff during use, and be particulate material but at present the daily ration of poultry adopts, so the very difficult mixing of medicine is in feedstuff.
Summary of the invention
The present invention is in order to overcome deficiency of the prior art, and for aviculture provides a kind of herbal medicine granule of preventing and treating poultry infectious bursal disease and preparation method thereof, its antibacterial antitoxic action is strong, and has a broad antifungal spectrum.All medicines cooperates the purpose that reaches treating both the principal and secondary aspects of a disease, and curative effect is outstanding, and no drug residue, problem has no side effect, has no drug resistance.
The present invention is achieved through the following technical solutions for achieving the above object: a kind of herbal medicine granule of preventing and treating poultry infectious bursal disease is characterized in that: be made up of following medicine, by weight meter
1～8 part of Gypsum Fibrosum, 1～5 part of Radix Isatidis, 1～3 part of the Radix Astragali,
1～3 part in the Radix Rehmanniae, 1～3 part of Cortex Moutan, 1～5 part in Radix Glycyrrhizae.
Above-mentioned Chinese medicine composition preferred ingredient is: 3 parts of Gypsum Fibrosum, 3 parts of Radix Isatidis, 3 parts of the Radixs Astragali, 2 parts in the Radix Rehmanniae, 2 parts of Cortex Moutans, 4 parts in Radix Glycyrrhizae.
A kind of herbal medicine granule of preventing and treating poultry infectious bursal disease, its preparation method is characterized in that: carry out as follows:
(1) takes by weighing 1～8 part of Gypsum Fibrosum, 1～5 part of Radix Isatidis, 1～3 part of the Radix Astragali, 1～3 part in the Radix Rehmanniae, 1～3 part of Cortex Moutan, Radix Glycyrrhizae by weight and be raw material for 1～5 part;
(2) above-mentioned Chinese medicine is decocted with water respectively twice, the each decoction 1.5 hours merges twice decoction liquor, filters, filtrate is concentrated into relative density and is about 1.08 clear paste, room temperature to be chilled to, the ethanol that adds equivalent makes precipitation, leaves standstill 30 minutes, getting supernatant concentration, to become relative density be 1.38～1.40 thick paste, an amount of with sucrose and glucide, mixing, spray drying is promptly.
Described Chinese medicine all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2005.
Composition principle of the present invention: Chinese veterinarian thinks that poultry infectious bursal disease belongs to the category of pestilence, and its etiology and pathogenesis is the pyretic toxicity invasion and attack, and pathogenic heat is not separated, and the blood system pathogenic heat is contained, and heat is YANG pathogen, easy impairment of body fluid liquid, thus the dehydration of sick chicken, the extreme thirst polydipsia.Pyretic toxicity very easily consumes the moving blood of body fluid, easily causes the origin exhaustion.Utilization traditional Chinese veterinary medicine determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs adopts treating both the principal and secondary aspects of a disease, the principles of formulating prescriptions of heat clearing away and usefulness, side's Gypsum Fibrosum, Radix Isatidis Fructus Forsythiae clearing away heat-fire, detoxifcation removing heat from blood; The resistance of Radix Astragali invigorating the spleen and replenishing QI, enhancing body, the formation of inducing interferon reaches antiviral purpose; The Radix Rehmanniae, Cortex Moutan clearing away heat and cooling blood, nourishing YIN to lower pathogenic fire; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, invigorating the spleen and replenishing QI.Experiment showed, that the not only antibacterial antitoxic action of medicine-feeding is strong, and has a broad antifungal spectrum.All medicines cooperate the purpose that reaches treating both the principal and secondary aspects of a disease.
Beneficial effect of the present invention: it has overcome vaccine and high immunity yolk antibody and other Chinese medicine preparation in the deficiency that exists aspect the control poultry infectious bursal disease.This medicine is owing to be pure herbal medicine granule, thus no any drug residue, without any side effects to body, and easy to use.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of herbal medicine granule of preventing and treating poultry infectious bursal disease is made up of following medicine, and every part by 10g,
Gypsum Fibrosum 30g, Radix Isatidis 30g, Radix Astragali 30g, Radix Rehmanniae 20g, Cortex Moutan 20g, Radix Glycyrrhizae 40g.
A kind of herbal medicine granule of preventing and treating poultry infectious bursal disease, its preparation method, carry out as follows:
(1) take by weighing Gypsum Fibrosum 30g, Radix Isatidis 30g, Radix Astragali 30g, Radix Rehmanniae 20g by weight, Cortex Moutan 20g, Radix Glycyrrhizae 40g are raw material;
(2) above-mentioned Chinese medicine is decocted with water respectively twice, the each decoction 1.5 hours merges twice decoction liquor, filters, filtrate is concentrated into relative density and is about 1.08 clear paste, room temperature to be chilled to, the ethanol that adds equivalent makes precipitation, leaves standstill 30 minutes, getting supernatant concentration, to become relative density be 1.38～1.40 thick paste, an amount of with sucrose and glucide, mixing, spray drying is promptly.
Embodiment 2
A kind of herbal medicine granule of preventing and treating poultry infectious bursal disease is made up of following medicine, and every part by 10g,
Gypsum Fibrosum 10g, Radix Isatidis 50g, Radix Astragali 10g, Radix Rehmanniae 30g, Cortex Moutan 10g, Radix Glycyrrhizae 10g.
Its preparation method takes by weighing Gypsum Fibrosum 10g, Radix Isatidis 50g, Radix Astragali 10g, Radix Rehmanniae 30g, Cortex Moutan 10g, Radix Glycyrrhizae 10g are raw material by weight; Undertaken by the step (2) of embodiment 1 again.
Embodiment 3
A kind of herbal medicine granule of preventing and treating poultry infectious bursal disease is made up of following medicine, and every part by 10g,
Gypsum Fibrosum 80g, Radix Isatidis 10g, Radix Astragali 10g, Radix Rehmanniae 10g, Cortex Moutan 30g, Radix Glycyrrhizae 10g.
Its preparation method takes by weighing Gypsum Fibrosum 80g, Radix Isatidis 10g, Radix Astragali 10g, Radix Rehmanniae 10g, Cortex Moutan 30g, Radix Glycyrrhizae 10g are raw material by weight; Undertaken by the step (2) of embodiment 1 again.
Embodiment 4
A kind of herbal medicine granule of preventing and treating poultry infectious bursal disease is made up of following medicine, and every part by 10g,
Gypsum Fibrosum 10g, Radix Isatidis 20g, Radix Astragali 15g, Radix Rehmanniae 15g, Cortex Moutan 15g, Radix Glycyrrhizae 50g.
Its preparation method takes by weighing Gypsum Fibrosum 10g, Radix Isatidis 20g, Radix Astragali 15g, Radix Rehmanniae 15g, Cortex Moutan 15g, Radix Glycyrrhizae 50g are raw material by weight; Undertaken by the step (2) of embodiment 1 again.
Clinical trial:
Medicine of the present invention is pressed the dosage of 1g/kg body weight, with hot water this product is washed open earlier, and then added an amount of drinking-water, freely drink for poultry.
For example: in May, 2007, Jinghai County plant raises table hens 8000, and when raising to 20 ages in days, taking place increases with drinking-water, and loss of appetite is arranged white loose stool, cuts open the inspection pathological change and is: the fabricius bursa severe haemorrhage, be the purple grape shape.After cutting fabricius bursa, the mucosa gauffer has petechia or ecchymosis, and purulent secretion is arranged in the blister cavities.Through laboratory diagnosis is poultry infectious bursal disease.Satisfy with herbal medicine granule of the present invention and press above-mentioned dosage treatment, medication after 3 days the state of an illness controlled.
The above only is preferred embodiment of the present invention, is not structure of the present invention is done any pro forma restriction.Every foundation technical spirit of the present invention all still belongs in the scope of technical scheme of the present invention any simple modification, equivalent variations and modification that above embodiment did.
Claims (3)
1. a herbal medicine granule of preventing and treating poultry infectious bursal disease is characterized in that: be made up of following medicine, by weight meter
1～8 part of Gypsum Fibrosum, 1～5 part of Radix Isatidis, 1～3 part of the Radix Astragali,
1～3 part in the Radix Rehmanniae, 1～3 part of Cortex Moutan, 1～5 part in Radix Glycyrrhizae.
2, the herbal medicine granule of control poultry infectious bursal disease according to claim 1 is characterized in that: preferred ingredient is 3 parts of Gypsum Fibrosum, 3 parts of Radix Isatidis, 3 parts of the Radixs Astragali, 2 parts in the Radix Rehmanniae, 2 parts of Cortex Moutans, 4 parts in Radix Glycyrrhizae.
3, a kind of herbal medicine granule of preventing and treating poultry infectious bursal disease, its preparation method is characterized in that: carry out as follows:
(1) takes by weighing 1～8 part of Gypsum Fibrosum, 1～5 part of Radix Isatidis, 1～3 part of the Radix Astragali, 1～3 part in the Radix Rehmanniae, 1～3 part of Cortex Moutan, Radix Glycyrrhizae by weight and be raw material for 1～5 part;
(2) above-mentioned Chinese medicine is decocted with water respectively twice, the each decoction 1.5 hours merges twice decoction liquor, filters, filtrate is concentrated into relative density and is about 1.08 clear paste, room temperature to be chilled to, the ethanol that adds equivalent makes precipitation, leaves standstill 30 minutes, getting supernatant concentration, to become relative density be 1.38～1.40 thick paste, an amount of with sucrose and glucide, mixing, spray drying is promptly.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810151753A CN101683429A (en) | 2008-09-25 | 2008-09-25 | Animal Chinese medicine granular formulation for preventing and treating infectious bursal disease of fowl and preparation method thereof |
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| CN200810151753A CN101683429A (en) | 2008-09-25 | 2008-09-25 | Animal Chinese medicine granular formulation for preventing and treating infectious bursal disease of fowl and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263527A (en) * | 2013-05-09 | 2013-08-28 | 广西百通动物药业有限公司 | Chicken high fever disease prevention and treatment traditional Chinese medicine and preparation method thereof |
| CN103520674A (en) * | 2013-09-27 | 2014-01-22 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treatment of infectious bursa fabricius disease of poultry |
| CN111135251A (en) * | 2020-01-09 | 2020-05-12 | 山西中医药大学 | Veterinary drug for preventing and treating chicken bursal disease as well as preparation method and application thereof |
| CN111388549A (en) * | 2020-02-22 | 2020-07-10 | 卢茂林 | Formula and preparation method of tea for treating viral diseases |
-
2008
- 2008-09-25 CN CN200810151753A patent/CN101683429A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263527A (en) * | 2013-05-09 | 2013-08-28 | 广西百通动物药业有限公司 | Chicken high fever disease prevention and treatment traditional Chinese medicine and preparation method thereof |
| CN103520674A (en) * | 2013-09-27 | 2014-01-22 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treatment of infectious bursa fabricius disease of poultry |
| CN111135251A (en) * | 2020-01-09 | 2020-05-12 | 山西中医药大学 | Veterinary drug for preventing and treating chicken bursal disease as well as preparation method and application thereof |
| CN111388549A (en) * | 2020-02-22 | 2020-07-10 | 卢茂林 | Formula and preparation method of tea for treating viral diseases |
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Open date: 20100331 |