CN104258362A - Traditional Chinese medicine preparation for treating peripheral neuritis - Google Patents
Traditional Chinese medicine preparation for treating peripheral neuritis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating peripheral neuritis. The traditional Chinese medicine preparation comprises the following raw materials: cassia twig, jujubes, notopterygium root, ginger, astragalus membranaceus, angelica, rhizoma cyperi, rhizoma atractylodis, loofah sponge, cinnamon, ephedra, prepared rehmannia root, peach kernels and liquorice. According to the traditional Chinese medicine preparation, the cassia twig, the ginger and the ephedra have the effects of warming channels, activating yang, inducing sweat and relieving exterior syndrome; the notopterygium root, the angelica, the rhizoma cyperi and the rhizoma atractylodis have the effects of expelling wind, removing cold and activating blood to relieve pain; the loofah sponge, the prepared rehmannia root and the peach kernels have the effects of activating blood to remove meridian obstruction, nourishing blood and yin, replenishing essence and benefiting marrow; the jujubes, the astragalus membranaceus, the cinnamon and the liquorice have the effects of invigorating the spleen and stomach, benefiting vital energy, replenishing vital energy for consolidating exterior, and warming and unblocking collaterals. The traditional Chinese medicine preparation is prepared by finely mixing the raw materials with complementary effects, treats both symptoms and root causes, gives full play to the advantage of dialectical therapy of traditional Chinese medicine, is used for treating the peripheral neuritis, has the effects of expelling wind, removing cold, activating blood to relieve pain, tonifying the spleen and stomach, benefiting vital energy and replenishing vital energy for consolidating exterior, and is worthy of clinical popularization and application.
Description
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation can treating peripheral neuritis.
Background technology
Peripheral neuritis is that the multiple peripheral nerve caused by many reasons damages, and is one common in neurosurgery related disease.Peripheral neuritis mainly changes relevant with axonal degeneration with perineural segmental demyelination.Producing reason has the heavy metals such as lead, arsenic, hydrargyrum, phosphorus, the organic compounds poisonings such as nitrofural class, isoniazid, streptomycin, organophosphorus pesticide, Nutrition and Metabolism obstacle, various acute and chronic infection, irritated, allergy, connective tissue disease, caused by hereditary.Generally can be divided into peripheral neuritis clinically: sensory disturbance, the dyskinesia, vegetative nerve functional disturbance.
Peripheral neuritis does not generally affect orthobiosis, but is in a bad way and can causes brothers, extremity and total numbness and can cause amyotrophy, adds uncertain danger, therefore answer active treatment to patient.Current doctor trained in Western medicine mainly adopts oral drugs and infusion, lack curative effect certainly, and effect is bad, side effect is more, patient is therefore very painful, for removing the misery of the mind & body of patient, according to the principle of tcm syndrome differentiation and treatment, treating both the principal and the secondary aspects of a disease at the same time, we provide a kind of Chinese medicine preparation, be used for the treatment of peripheral neuritis and achieve satisfied effect.
Summary of the invention
Instant invention overcomes the technical deficiency existed in treatment peripheral neuritis at present, provide a kind of evident in efficacy, cheap, patient compliance is higher, cure after the Chinese medicine preparation that not easily recurs.
The technical solution adopted in the present invention is:
Treat a Chinese medicine preparation for peripheral neuritis, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Ramulus Cinnamomi 20-30 gram, Fructus Jujubae 10-20 gram, Rhizoma Et Radix Notopterygii 10-20 gram, Rhizoma Zingiberis Recens 10-20 gram, Radix Astragali 10-20 gram, Radix Angelicae Sinensis 8-15 gram, Rhizoma Cyperi 8-15 gram, Rhizoma Atractylodis 8-15 gram, Retinervus Luffae Fructus 8-15 gram, Cortex Cinnamomi 6-10 gram, Herba Ephedrae 6-10 gram, Radix Rehmanniae Preparata 6-10 gram, Semen Persicae 6-10 gram, Radix Glycyrrhizae 6-10 gram.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Ramulus Cinnamomi 20 grams, 10 grams, Fructus Jujubae, Rhizoma Et Radix Notopterygii 10 grams, 10 grams, Rhizoma Zingiberis Recens, the Radix Astragali 10 grams, Radix Angelicae Sinensis 8 grams, Rhizoma Cyperi 8 grams, Rhizoma Atractylodis 8 grams, Retinervus Luffae Fructus 8 grams, Cortex Cinnamomi 6 grams, 6 grams, Herba Ephedrae, 6 grams, Radix Rehmanniae Preparata, 6 grams, Semen Persicae, 6 grams, Radix Glycyrrhizae.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Ramulus Cinnamomi 25 grams, 15 grams, Fructus Jujubae, Rhizoma Et Radix Notopterygii 15 grams, 15 grams, Rhizoma Zingiberis Recens, the Radix Astragali 15 grams, Radix Angelicae Sinensis 12 grams, Rhizoma Cyperi 12 grams, Rhizoma Atractylodis 12 grams, Retinervus Luffae Fructus 12 grams, Cortex Cinnamomi 8 grams, 8 grams, Herba Ephedrae, 8 grams, Radix Rehmanniae Preparata, 8 grams, Semen Persicae, 8 grams, Radix Glycyrrhizae.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Ramulus Cinnamomi 30 grams, 20 grams, Fructus Jujubae, Rhizoma Et Radix Notopterygii 20 grams, 20 grams, Rhizoma Zingiberis Recens, the Radix Astragali 20 grams, Radix Angelicae Sinensis 15 grams, Rhizoma Cyperi 15 grams, Rhizoma Atractylodis 15 grams, Retinervus Luffae Fructus 15 grams, Cortex Cinnamomi 10 grams, 10 grams, Herba Ephedrae, 10 grams, Radix Rehmanniae Preparata, 10 grams, Semen Persicae, 10 grams, Radix Glycyrrhizae.
The instructions of taking of Chinese medicine preparation of the present invention is: after being mixed by the raw material Chinese medicine of above-mentioned weight proportion, 1 dose/day, every agent head decocts the 500ml that adds water, and warm fire boils 25 minutes, extracting juice 250ml; Two decoct the 300ml that adds water, and warm fire boils 20 minutes, extracting juice 150ml.Two decoct mixing, sooner or later empty stomach decoction being taken hot.25 doses was 1 course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature; GUIXIN, lung, urinary bladder channel.There is relieving the exterior syndrome by diaphoresis, effect of warming the meridian for promoting the flow of YANG QI.
Fructus Jujubae: sweet in the mouth, warm in nature; Return spleen, stomach warp.There is invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relax effect of the property of medicine.
Rhizoma Et Radix Notopterygii: acrid in the mouth, warm in nature; Return bladder, kidney channel.There is the effect in expelling wind and cold, sharp joint.
Rhizoma Zingiberis Recens: acrid in the mouth, slightly warm in nature; Return lung, spleen channel.There is relieving the exterior syndrome by diaphoresis, warming middle-JIAO to stop vomiting, effect of warming the lung to relieve cough.
The Radix Astragali: sweet in the mouth, slightly warm in nature; Return spleen, lung meridian.Have tonifying Qi and lifting yang, benefit defends consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, effect of inducing diuresis to remove edema.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature; Return liver, the heart, spleen channel.There is promoting blood circulation and stopping pain, tonifying blood and regulating menstruation, effect of loosening bowel to relieve constipation.
Rhizoma Cyperi: acrid in the mouth, micro-hardship, micro-sweet, property is put down; Return liver, tri-jiao channel.There is depressed liver-energy dispersing and QI regulating, effect of menstruction regulating and pain relieving.
Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature; Return spleen, stomach warp.Have drying damp and strengthening spleen, ward off dirty, effect of wind-damp dispelling.
Retinervus Luffae Fructus: sweet in the mouth, property are flat; Return lung, stomach, Liver Channel.There is effect of heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, inducing diuresis to remove edema.
Cortex Cinnamomi: acrid in the mouth, sweet, hot in nature; Return kidney, spleen, the heart, Liver Channel.There is benefit fire supporing yang, dispersing cold for relieving pain, effect of promoting the flow of QI-blood by warming the meridian.
Herba Ephedrae: acrid in the mouth, micro-hardship, warm in nature; Return lung, urinary bladder channel.There is relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, effect of inducing diuresis to remove edema.
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature; Return liver, kidney channel.There is nourishing the blood and yin, effect of vital essence replenishing and marrow benifiting.
Semen Persicae: bitter in the mouth, property is put down; GUIXIN, liver, lung, large intestine channel.There is blood circulation promoting and blood stasis dispelling, effect of loosening bowel to relieve constipation.
Radix Glycyrrhizae: sweet in the mouth, property is put down; GUIXIN, spleen, lung, stomach warp.There is invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, heat-clearing and toxic substances removing, alleviate pain relieving, relax effect of the property of medicine.
Peripheral neuritis belongs to the traditional Chinese medical science " BI-syndrome involved the blood vessels " category, its cause of disease more complicated, and exopathogenic factor is many paddled with severe winter, stride ice and snow, nine occupies wetland or bear a heavy burden and go on a long journey, and caused the invasion of wind and cold Shi Re Bing Pian relevant; Endogenous cause of ill is then mainly internal organs imbalance of YIN and YANG, positive QI-insufficiency, and blood vessels numbness hinders, affect that battalion defends, the operation of QI and blood, body fluid or blood stasis, expectorant turbid caused by form.
Modern medicine thinks the generation of primary disease and heavy metal poisoning, Nutrition and Metabolism obstacle, various acute and chronic infection, allergy, allergy are relevant, therefore treat primary disease to show according to patient's different symptoms, defend consolidating superficial resistance with expelling wind and cold, invigorating the spleen and replenishing QI, benefit, fundamentally adjust body internal organs, battalion defends, QI and blood, dialectical treatment, applies in a flexible way, and Fang Xianqi is imitated.
In Chinese medicine preparation of the present invention, Ramulus Cinnamomi, Rhizoma Zingiberis Recens, Herba Ephedrae can warming the meridian for promoting the flow of YANG QI, relieving the exterior syndrome by diaphoresis; Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, Rhizoma Cyperi, Rhizoma Atractylodis can relieving rheumatism and cold, invigorating blood circulation and stopping pains; Retinervus Luffae Fructus, Radix Rehmanniae Preparata, Semen Persicae can promoting blood circulation to remove obstruction in the collateral, nourishing the blood and yin, vital essence replenishing and marrow benifiting; Fructus Jujubae, the Radix Astragali, Cortex Cinnamomi, Radix Glycyrrhizae can invigorating the spleen and replenishing QI, and benefit defends consolidating superficial resistance, warming the meridian and promoting blood circulation.Full side's compatibility is superior, attacks benefit and executes mutually, treating both the principal and secondary aspects of a disease, has given full play to the advantage that differential diagnosis in tcm treats, has been used for the treatment of peripheral neuritis, has expelling wind and cold, a merit that promoting blood circulation and stopping pain, invigorating the spleen and replenishing QI, benefit defend consolidating superficial resistance, clinic promotion and application.
For investigating clinical efficacy and the safety of medicine of the present invention further, we select the routine out-patient of certain hospital 66 to carry out clinical trial; Minimum 40 years old of age, maximum 72 years old, average 56 years old; The course of disease is the shortest 0.5 year, the longest 3 years, average 1.8 years; Sensory disturbance patient 38 example, dyskinesia patient 12 example, vegetative nerve functional disturbance patient 16 example.
Criterion of therapeutical effect:
Cure: clinical symptoms, sign disappear, limbs sensation and motor capacity recover completely.
Effective: clinical symptoms, sign obviously alleviate, muscular strength strengthens, and amyotrophy is obviously improved, limbs pain, and numb degree obviously alleviates before comparatively treating.
Effective: clinical symptoms, sign slightly alleviated, limbs pain, numb sensation alleviates to some extent.
Invalid: clinical symptoms, sign all remain unchanged, do not improve completely.
Therapeutic Method:
After being mixed by the raw material Chinese medicine of above-mentioned weight proportion, 1 dose/day, every agent head decocts the 500ml that adds water, and warm fire boils 25 minutes, extracting juice 250ml; Two decoct the 300ml that adds water, and warm fire boils 20 minutes, extracting juice 150ml.Two decoct mixing, sooner or later empty stomach decoction being taken hot.25 doses was 1 course for the treatment of.
Efficacy result:
1. clinical efficacy result:
After treatment, cure 32 examples, effective 19 examples, effective 11 examples, invalid 4 examples; Cure rate 48.5%, obvious effective rate 28.9%, effective percentage 16.7%, inefficiency 6.1%, total effective rate 93.90%.Detailed results is in table 1.
Table 1: clinical efficacy result table after treatment
Number of cases | Cure n (%) | Effective n (%) | Effective n (%) | Invalid n (%) | Effective percentage n (%) |
66 | 32(48.5) | 19(28.9) | 11(16.7) | 4(6.1) | 62(93.9) |
2. classifying type disease efficacy result:
After treatment, statistics finds, sensory disturbance treated effect is 97.4%, dyskinesia treated effect is 83.3%, vegetative nerve functional disturbance treated effect is 93.8%, can treat in adenofibroma of breast by Chinese medicine preparation of the present invention, curative effect is the sensory disturbance > vegetative nerve functional disturbance > dyskinesia.Detailed results is in table 2.
Table 2: classifying type disease efficacy result synopsis
Disease title | Number of cases n | Cure n | Effective n | Effective n | Invalid n | Effective percentage (%) |
Sensory disturbance | 38 | 22 | 6 | 9 | 1 | 97.4 |
The dyskinesia | 12 | 4 | 5 | 1 | 2 | 83.3 |
Vegetative nerve functional disturbance | 16 | 6 | 8 | 1 | 1 | 93.8 |
3. side effect reaction
In the treatment, all there is not obvious adverse reaction in all patients.
Result shows, Chinese medicine preparation of the present invention is by Chinese medicine differential diagnosis of diseases and the dialectical principle combined, attack and mend double making, treating both the principal and the secondary aspects of a disease at the same time, be used for the treatment of that peripheral neuritis is evident in efficacy, cure rate is high and not easily recur, avoid the side effect that Drug therapy is brought simultaneously, there is certain advantage, clinic promotion and application.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of peripheral neuritis, chooses Ramulus Cinnamomi 20 grams, 10 grams, Fructus Jujubae, Rhizoma Et Radix Notopterygii 10 grams, 10 grams, Rhizoma Zingiberis Recens, the Radix Astragali 10 grams, Radix Angelicae Sinensis 8 grams, Rhizoma Cyperi 8 grams, Rhizoma Atractylodis 8 grams, Retinervus Luffae Fructus 8 grams, Cortex Cinnamomi 6 grams, 6 grams, Herba Ephedrae, 6 grams, Radix Rehmanniae Preparata, 6 grams, Semen Persicae, 6 grams, Radix Glycyrrhizae.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of peripheral neuritis, chooses Ramulus Cinnamomi 25 grams, 15 grams, Fructus Jujubae, Rhizoma Et Radix Notopterygii 15 grams, 15 grams, Rhizoma Zingiberis Recens, the Radix Astragali 15 grams, Radix Angelicae Sinensis 12 grams, Rhizoma Cyperi 12 grams, Rhizoma Atractylodis 12 grams, Retinervus Luffae Fructus 12 grams, Cortex Cinnamomi 8 grams, 8 grams, Herba Ephedrae, 8 grams, Radix Rehmanniae Preparata, 8 grams, Semen Persicae, 8 grams, Radix Glycyrrhizae.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of peripheral neuritis, chooses Ramulus Cinnamomi 30 grams, 20 grams, Fructus Jujubae, Rhizoma Et Radix Notopterygii 20 grams, 20 grams, Rhizoma Zingiberis Recens, the Radix Astragali 20 grams, Radix Angelicae Sinensis 15 grams, Rhizoma Cyperi 15 grams, Rhizoma Atractylodis 15 grams, Retinervus Luffae Fructus 15 grams, Cortex Cinnamomi 10 grams, 10 grams, Herba Ephedrae, 10 grams, Radix Rehmanniae Preparata, 10 grams, Semen Persicae, 10 grams, Radix Glycyrrhizae.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is verified further:
Case 1
What so-and-so, women 56 years old.Patient 2 years presensation brothers have numbness slightly to feel, do not go hospitalize in time, cause aggravation, rear employing western medicine, has no obvious curative effects, and present muscular strength goes down, and motion has obstacle slightly.Show through examination in hospital: muscular strength goes down, Tendon defection, tendon reflex weaken.Be diagnosed as: the dyskinesia caused by peripheral neuritis.Take Chinese medicine preparation of the present invention upon somebody's introduction to treat, take medicine 10 doses, without uncomfortable.Serve on 20 days, motor capacity recovers gradually, and following the service 2 months, recovers completely.Follow up a case by regular visits to 1 year without recurrence.
Case 2
Dong so-and-so, man, 61 years old.Patient's presensation half a year finger and toe end is burnt, pain, numb etc. feel not give timely treatment, engenders hypoesthetic symptom afterwards.Remove hospital admission, the sensory disturbance of diagnosis caused by peripheral neuritis, after take Chinese medicine preparation of the present invention and treat, after the course for the treatment of of taking medicine, symptom is improved substantially, takes two courses for the treatment of continuously, rehabilitation substantially afterwards.Follow up a case by regular visits to half a year without recurrence.
Case 3
Hole so-and-so, man, 43 years old.Patient is in occurring that acra skin is sent out cool, pale symptom two months ago, and hypohidrosis, skin liver is coarse, and fingernail tarnishes.Remove hospital admission, be diagnosed as the vegetative nerve functional disturbance caused by peripheral neuritis, after take Chinese medicine preparation of the present invention and treat, after taking 40 days, transference cure.Follow up a case by regular visits to half a year without recurrence.
Claims (4)
1. treat a Chinese medicine preparation for peripheral neuritis, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Ramulus Cinnamomi 20-30 gram, Fructus Jujubae 10-20 gram, Rhizoma Et Radix Notopterygii 10-20 gram, Rhizoma Zingiberis Recens 10-20 gram, Radix Astragali 10-20 gram, Radix Angelicae Sinensis 8-15 gram, Rhizoma Cyperi 8-15 gram, Rhizoma Atractylodis 8-15 gram, Retinervus Luffae Fructus 8-15 gram, Cortex Cinnamomi 6-10 gram, Herba Ephedrae 6-10 gram, Radix Rehmanniae Preparata 6-10 gram, Semen Persicae 6-10 gram, Radix Glycyrrhizae 6-10 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Ramulus Cinnamomi 20 grams, 10 grams, Fructus Jujubae, Rhizoma Et Radix Notopterygii 10 grams, 10 grams, Rhizoma Zingiberis Recens, the Radix Astragali 10 grams, Radix Angelicae Sinensis 8 grams, Rhizoma Cyperi 8 grams, Rhizoma Atractylodis 8 grams, Retinervus Luffae Fructus 8 grams, Cortex Cinnamomi 6 grams, 6 grams, Herba Ephedrae, 6 grams, Radix Rehmanniae Preparata, 6 grams, Semen Persicae, 6 grams, Radix Glycyrrhizae.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Ramulus Cinnamomi 25 grams, 15 grams, Fructus Jujubae, Rhizoma Et Radix Notopterygii 15 grams, 15 grams, Rhizoma Zingiberis Recens, the Radix Astragali 15 grams, Radix Angelicae Sinensis 12 grams, Rhizoma Cyperi 12 grams, Rhizoma Atractylodis 12 grams, Retinervus Luffae Fructus 12 grams, Cortex Cinnamomi 8 grams, 8 grams, Herba Ephedrae, 8 grams, Radix Rehmanniae Preparata, 8 grams, Semen Persicae, 8 grams, Radix Glycyrrhizae.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Ramulus Cinnamomi 30 grams, 20 grams, Fructus Jujubae, Rhizoma Et Radix Notopterygii 20 grams, 20 grams, Rhizoma Zingiberis Recens, the Radix Astragali 20 grams, Radix Angelicae Sinensis 15 grams, Rhizoma Cyperi 15 grams, Rhizoma Atractylodis 15 grams, Retinervus Luffae Fructus 15 grams, Cortex Cinnamomi 10 grams, 10 grams, Herba Ephedrae, 10 grams, Radix Rehmanniae Preparata, 10 grams, Semen Persicae, 10 grams, Radix Glycyrrhizae.
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Publication number | Priority date | Publication date | Assignee | Title |
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CN104667105A (en) * | 2015-03-16 | 2015-06-03 | 侯荣耀 | Chinese patent medicine for treating facial neuritis and preparation method for Chinese patent medicine |
CN105250569A (en) * | 2015-11-26 | 2016-01-20 | 王茂凯 | Traditional Chinese medicine pill for treating peripheral neuritis and preparation method |
CN105412614A (en) * | 2015-12-16 | 2016-03-23 | 蒋中平 | Traditional Chinese medicine composition for treating toxic peripheral neuritis and preparation method thereof |
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CN102430102A (en) * | 2011-12-07 | 2012-05-02 | 哈药集团中药二厂 | Preparation method for huangqi-guizhi-wuwu granule |
CN102895630A (en) * | 2011-07-29 | 2013-01-30 | 苏州知微堂生物科技有限公司 | Preparation technology and production method for integrated new formulation of astragalus and cinnamon twig five agents decoction |
CN102988666A (en) * | 2012-09-27 | 2013-03-27 | 李承平 | Cassia twig tablets for warming channel and expelling cold |
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CN102895630A (en) * | 2011-07-29 | 2013-01-30 | 苏州知微堂生物科技有限公司 | Preparation technology and production method for integrated new formulation of astragalus and cinnamon twig five agents decoction |
CN102430102A (en) * | 2011-12-07 | 2012-05-02 | 哈药集团中药二厂 | Preparation method for huangqi-guizhi-wuwu granule |
CN102988666A (en) * | 2012-09-27 | 2013-03-27 | 李承平 | Cassia twig tablets for warming channel and expelling cold |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104667105A (en) * | 2015-03-16 | 2015-06-03 | 侯荣耀 | Chinese patent medicine for treating facial neuritis and preparation method for Chinese patent medicine |
CN105250569A (en) * | 2015-11-26 | 2016-01-20 | 王茂凯 | Traditional Chinese medicine pill for treating peripheral neuritis and preparation method |
CN105412614A (en) * | 2015-12-16 | 2016-03-23 | 蒋中平 | Traditional Chinese medicine composition for treating toxic peripheral neuritis and preparation method thereof |
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