CN105250569A - Traditional Chinese medicine pill for treating peripheral neuritis and preparation method - Google Patents

Traditional Chinese medicine pill for treating peripheral neuritis and preparation method Download PDF

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CN105250569A
CN105250569A CN201510835797.1A CN201510835797A CN105250569A CN 105250569 A CN105250569 A CN 105250569A CN 201510835797 A CN201510835797 A CN 201510835797A CN 105250569 A CN105250569 A CN 105250569A
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blood
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王茂凯
刘京平
任日军
陈焕磊
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Abstract

The invention discloses a traditional Chinese medicine pill for treating peripheral neuritis and a preparation method, and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine pill is prepared from ficus sarmentosa var. impressa, cassia twigs, caulis trachelospermi, angelica sinensis, roots or stems of smoothfruit ventilago, roots of silverweed cinquefoil, herbs of gold stargrass, largehead atractylodes rhizome, common macrocarpium fruit, radix codonopsis, Japan sabia, flos carthami, white mustard seeds, licorice roots, fructus lycii, radix morindae officinalis, fructus psoraleae, stems of champion bauhinia, black sesame, sappan wood, common clubmoss herbs, radix cyathulae, areca peels and mountain spicy tree fruits. Medicinal materials are selected and suit the remedy to the case, the effects of nourishing the liver and the kidney, warming the kidney, enhancing Yang, invigorating the spleen, replenishing Qi, enriching and activating the blood, removing blood stasis, warming channels, expelling cold, promoting Qi to activate the blood, activating collaterals and eliminating stagnation are achieved, the absorbing effect is good, the curative effect is obvious, toxic and side effects and an adverse reaction do not exist, and the cure rate to the peripheral neuritis is higher through clinical verification.

Description

A kind of medicine pill and preparation method being used for the treatment of peripheral neuritis
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine pill and the preparation method that are used for the treatment of peripheral neuritis.
Background technology
The general name that the multiple peripheral nerve that peripheral neuritis system is caused by many reasons damages, shows as far-end of limb symmetry sensation, motion and vegetative nerve functional disturbance, therefore also known as polyneuritis or multiple peripheral neuritis.Take far-end of limb as the symmetry sensation of work, motion and vegetative nerve functional disturbance, and normal heavier with lower limb.Peripheral neuritis main manifestations is brothers or numb limbs and tense tendons, can with pain, powerlessness.The lighter refers to (toe), and end is numb, severe one may extend to whole palm and foot, extremity, even whole body, stolidity is stranded swollen, joint stuffiness, move dumb, " Formica fusca climbs the same " or " acupuncture sample sensation ", some patients has " socks ", " oversleeve " type abnormal sensory, conscious skin is thickening the same, insensitive, many patients often show effect when nighttime sleep, so that fiber crops are waken up, or both hands are stranded swollen after getting up morning, numbness and uncomfortableness stiff sense, slightly can alleviate after do activity, above symptom is being caught cold, often increase the weight of after fatigue, with spiritlessness and weakness, cool grade for performance is afraid of in trick.Few patients also has the abnormal sensory of some complexity, and sole is as stepped on the abnormal sense of Cotton Gossypii or cobblestone sample or tactile thing sensation of pricking, burn feeling, electrical sensation.The course of disease seriously can have amyotrophy.But most of patients state of an illness initial stage extremity motor function can be normal, generally do not affect Working Life, laboratory examination nervous system is also without obvious damage pathological changes.Primary disease is chronic progression, year more than can continuing the several years to ten.
Doctor trained in Western medicine is to the pathogenic factor of primary disease and imperfectly understand, and it is main for treating mainly with Symptomatic medicine, and doctor trained in Western medicine thinks that primary disease still belongs to difficult disease at present, and lack curative effect certainly, comparatively speaking, effect is bad, and side effect is more.
Primary disease is that cold-damp is kept due to ferritic deficient qi and blood in the traditional Chinese medical science, stops up air resister, and QI-blood circulation is smooth, caused by meridians must not be dredged, controls suitable benefiting qi and nourishing blood, dispelling cold and dehumidification, therapeutic method to keep the adverse QI flowing downwards the turbid descending, dredging the meridian.As publication No. CN104623600A (application number: Chinese patent literature 201510048767.6) discloses a kind of Chinese medicine for the treatment of peripheral neuritis and preparation method thereof, the Chinese medicine of this treatment peripheral neuritis is made up of following raw material: Radix Rehmanniae Preparata, Rhizoma Zingiberis, Radix Polygalae, Semen Persicae, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Radix Saposhnikoviae, Concha Margaritifera, Semen Vaccariae, Poria, Caulis Spatholobi, Arillus Longan, Fructus Jujubae, Rhizoma Gastrodiae, Herba Lycopodii Obscuri, Radix Cynanchi Paniculati, nine sons not from mother, Radix Glycyrrhizae.It is considered herein that primary disease belongs to the traditional Chinese medical science " arthralgia due to stagnation of blood ", " arthralgia due to cold " category, main pathogenesis is deficiency of YIN affecting YANG, yang deficiency cold coagulation, stasis blocking venation, and channels loses supports, functional disorder and occur many clinical manifestations.From function analysis, primary disease with kidney asthenia as the principal aspect, and relates to liver spleen, and The liver and the kidney have a common source, the interpromoting relation in five elements of spleen kidney.Liver governing tendons, main catharsis, the kidney being the origin of congenital constitution, the spleen being the foundation of acquired constitution.Spleen kidney mutual promotion, spleen governing limbs muscle, all feels closely related with extremity.Therefore Chinese medicine selected by medicine of the present invention, suit the remedy to the case for the cause of disease, Radix Morindae Officinalis, Fructus Psoraleae in side, Herba hypoxis aureae can warming the kidney to activate YANG; Fructus Corni in side, Fructus Lycii, Semen Sesami Nigrum can nourishing the liver nourishing kidneys; Radix Codonopsis in side, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Radix potentillae anserinae can invigorating the spleen and benefiting QI, enrich blood and invigorate blood circulation; Flos Carthami in side, Lignum Sappan can blood circulation promoting and blood stasis dispelling; Ramulus Cinnamomi in side, Semen Sinapis Albae, clear Fructus Solani melongenae can dispelling cold by warming the meridian, removing obstruction in the collateral to relieve pain; In side, Radix Cyathulae can eliminating blood stasis and inducing menstruation, conducting blood to flow downwards, strengthens activating blood and removing stasis, the strength of relaxing muscles and tendons and activating QI and blood in the collateral simultaneously; In side, the Chinese medicine such as Caulis Trachelospermi, Caulis Sinomenii, Radix seu Caulis Verntilaginis Leiocarpae, Caulis Bauhihiae Championii, Martin fig, Pericarpium Arecae can expelling wind and removing dampness, promoting flow of QI and blood, resolving mass and removing the obstruction of the collateral; In side, Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription; All medicines share and play nourishing the liver nourishing kidney, warming the kidney to activate YANG, invigorating the spleen and replenishing QI altogether, enrich blood invigorate blood circulation, effect of blood circulation promoting and blood stasis dispelling, dispelling cold by warming the meridian, promoting flow of QI and blood, resolving mass and removing the obstruction of the collateral, medicine Jian Lihong, specially heavily attack heresy, removal network is trembled with fear, and QI and blood is unobstructed, and channels is moistened, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to peripheral neuritis cure rate through clinical verification.
Summary of the invention
The invention provides a kind of medicine pill and the preparation method that are used for the treatment of peripheral neuritis, there is nourishing the liver nourishing kidney, warming the kidney to activate YANG, invigorating the spleen and replenishing QI, enrich blood invigorate blood circulation, effect of blood circulation promoting and blood stasis dispelling, dispelling cold by warming the meridian, promoting flow of QI and blood, resolving mass and removing the obstruction of the collateral, cure the disease and ask source treating both the principal and secondary aspects of a disease, to the peripheral neuritis that a variety of causes causes, all there is good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine pill for peripheral neuritis, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Be used for the treatment of a preparation method for the medicine pill of peripheral neuritis, comprise following processing step:
(1) Martin fig, Ramulus Cinnamomi, Radix potentillae anserinae, Herba hypoxis aureae, Fructus Corni, Flos Carthami, Semen Sinapis Albae, Fructus Lycii, Radix Morindae Officinalis, Caulis Bauhihiae Championii, Semen Sesami Nigrum, Lignum Sappan, Pericarpium Arecae are cleaned, dried rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; The water of 4 ~ 6 times amount is added again, heated and boiled 1 ~ 2 hour, immersion after cooling in remaining medicinal residues; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Caulis Trachelospermi, Radix Angelicae Sinensis, Radix seu Caulis Verntilaginis Leiocarpae, Caulis Sinomenii, Herba Lycopodii, Radix Cyathulae are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) put in pot by Rhizoma Atractylodis Macrocephalae sheet and fry with high heat to coke yellow, spray clear water, taking-up is dried, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(4) be placed in the pot of heating by wheat bran, when playing cigarette to pot, add Radix Codonopsis sheet, stir to buff, take out sieve and remove wheat bran, cool, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(5) get clean Radix Morindae Officinalis, mix thoroughly with saline, enter cage and steam thoroughly, pump core, dry, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(6) get clean Fructus Psoraleae saline to mix thoroughly, micro-profit, put in pot to fry with slow fire and heave to micro-, take out, dry, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(7) get clean Radix Glycyrrhizae tabellae, add cooked Mel and a little boiled water, slightly vexed after mixing thoroughly, put in parch container, slow fire is fried to yellow to buff, and take out time tack-free, cool, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(8) by clear Fructus Solani melongenae removing impurity and residual fruit stem, clean, dry, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(9) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), step (6), step (7), step (8), add after refined honey stirs, be prepared as the pill of every 3g.
The property of medicine of the present invention's Chinese medicine used is as follows:
Martin fig: acrid in the mouth; Sweet; Warm in nature.Expelling wind and removing dampness; Promoting flow of QI and blood; Reducing swelling and alleviating pain.Cure mainly rheumatic arthralgia; Nervous headache; Infantile convulsion; Stomachache; Traumatic injury.
Ramulus Cinnamomi: acrid in the mouth; Sweet; Warm in nature.Enter bladder; The heart; Lung meridian.Expelling cold and relieving exterior syndrome; Promoting the flow of QI-blood by warming the meridian; Activating YANG and prormoting functioning of QI.Cure mainly exterior syndrome due to wind-cold; Arthralgia due to cold-dampnes; Extreme cold of the limbs; Amenorrhea dysmenorrhea; WEIJIA is lumpd; The thoracic obstruction; Cardiopalmus; Phlegm retention; Dysuria." Changsha medicine solution " carries: " enter liver man and promoting the circulation of blood divides, determine meridians and reach Rong Yu.Kind solution ailment said due to cold or exposure, adjusts wood gas most.The detrapping of sending up the lucid YANG, the punching of the turbid descending the moon is inverse, the anxious contraction of relaxing muscles and tendons feeling pulse; The heap soil or fertilizer over and around the roots resistance in profit joint.Enter liver and gall and loose to suppress, pole pain relieving Chu, the meridian dredging and to open numbness puckery, very drying cold.Can renal mass be stopped, more pacify palpitation with fear." modern medicine study confirm, Ramulus Cinnamomi can effectively blood vessel dilating, promote diaphoresis, contained cinnamic aldehyde, natrium cinnamicum have antipyretic, analgesia, calmness, anticonvulsant action, in addition Ramulus Cinnamomi antibacterial, antiviral effect in addition.
Caulis Trachelospermi: bitter in the mouth; Pungent; Cold nature.Enter the heart; Liver; Kidney channel.Removing obstruction in the collateral to relieve pain; Heat clearing and blood cooling; Removing toxic substances and promoting subsidence of swelling.Cure mainly rheumatic arthralgia; Soreness of waist and knee joint; The contracture of muscle arteries and veins; Laryngopharynx swelling and pain; Furuncle swelling toxin; Traumatic injury; Traumatic hemorrhage." book on Chinese herbal medicine justice " carries: " this thing is apt to away passages through which vital energy circulates, sensible podomere, and the dead flesh of main air heat, supports kidney, main waist hip pain, hard muscle, sharp joint." modern medicine study confirms, Caulis Trachelospermi has stronger resistancing action to staphylococcus aureus, shigella flexneri and Bacillus typhi, and contained arctigenin can stimulate central nervous system, accelerates respiratory frequency, suppresses blood vessel edema.
Radix Angelicae Sinensis: sweet in the mouth; Pungent; Warm in nature.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation; Menstruction regulating and pain relieving; Loosening bowel to relieve constipation.Cure mainly blood deficiency and yellow complexion; Dizzy cardiopalmus; Asthenia cold abdominalgia; Rheumatic arthralgia; Injury from falling down; Ulcer sores." book on Chinese herbal medicine is just " carries: " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable." modern medicine study confirmation, Radix Angelicae Sinensis has antibacterial, antiinflammation, has obvious inhibitory action to chronic articular rheumatism acute attack.
Radix seu Caulis Verntilaginis Leiocarpae: sweet in the mouth; Warm in nature.Return lung; Spleen channel.Fill blood; Bone and muscle strengthening; Relax meridians.Cure mainly deficient qi and blood; Have through uncomfortable; Blood deficiency amenorrhea; Rheumatalgia; Traumatic injury; Lumbar muscle strain." conventional Chinese herbal medicine handbook ": rich in nutrition, relaxing muscles and tendons and activating QI and blood in the collateral.Control deficiency of both QI and blood, menoxenia, bones and muscles pain due to rheumatism, numb limbs and tense tendons, traumatic injury.
Radix potentillae anserinae: sweet in the mouth; Bitter; Cold.Return spleen; Stomach warp.Fill blood, strengthening the spleen and stomach, promoting the production of body fluid to quench thirst, dampness removing.For anemia after being ill, malnutrition, insufficiency of the spleen diarrhoea, rheumatic arthralgia." Chinese herbal medicine is commonly used in Tibet ": " vigorate qi and replenish the blood, controls insufficiency of the spleen diarrhoea, after being ill anemia, malnutrition for invigorating spleen and reinforcing stomach, promoting the production of body fluid to quench thirst." modern study proves: Radix potentillae anserinae contains two kinds of compositions of contraction and relaxing smooth muscle, has certain influence, and have cardiotonic to smooth muscle.
Herba hypoxis aureae: sweet in the mouth, micro-pungent, warm in nature.Warming the kidney to invigorate YANG; Regulating QI to relieve pain.Cure mainly lumbago due to renal deficiency; Sexual impotence; Insomnia; Colic of cold type is suffered from abdominal pain." Guizhou medical herbs ": the kidney warming regulating QI.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; Stomach warp.Invigorating the spleen and benefiting QI; Dampness diuretic; Hidroschesis; Antiabortive.Cure mainly deficiency-weakness of spleen-QI; Spiritlessness and weakness; Lack of appetite abdominal distention; Large loose stool is thin; Fluid-retention stagnating in the interior; Dysuria; Edema; Dizziness due to fluid-retention; Arthralgia chiefly caused by damp pathogen is ached; Spontaneous sweating due to deficiency of QI; Frequent fetal movement." herbal classic is met former " carries: " art, raw with there being dehumidifying benefit dry, expectorant diuretic, controls anemofrigid-damp arthralgia, dead flesh convulsion subcutaneous ulcer, blood between loose waist umbilicus, and chong channel is disease, the merit of inverse gas pain in the abdomen; Make ripe, have and middle QI invigorating, slake thirst and help produce saliva, hidroschesis heat extraction, enters diet, antiabortive effect." modern medicine study confirms, the Rhizoma Atractylodis Macrocephalae has diuresis, blood sugar lowering, strong, anticoagulation, antitumor, antibacterial, the effect that promotes hemopoietic and protein synthesis.
Fructus Corni: sour in the mouth; Slightly warm in nature, returns liver; Kidney channel.Liver and kidney tonifying; Convergence is solid de-, cures mainly: waist is had a dizzy spell; Deafness and tinnitus; Soreness of the waist and knees; Xian essence spermatorrhea; Frequent micturition; Incessant sweating due to debility; Woman uterine bleeding." herbal classic is met former ": Fructus Corni energy diaphoresis in detail, when being energy arresting sweating mistake.Receive with its acid, acomia inducing vomiting reason.Zhong Jing eight taste ball with it, lid kidney qi be benefited, then seal degree of keeping, liver-yin must be supported, then catharsis is without anxiety, and yi and Kui are derived from the same origin is also.Modern medicine study shows: Fructus Corni has antibacterial, immunity moderation, blood sugar lowering, blood fat reducing, antioxidation, anticancer, the function such as anti-AIDS, heart tonifying.
Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Strengthening the spleen and tonifying the lung; Supplementing QI for promoting the production of body fluid.Cure mainly weakness of the spleen and stomach; Anorexia and loose stool; Limbs fatigue; The deficiency of the lung is breathed with cough; To breathe hard spontaneous perspiration; The all cards of deficiency of both QI and blood." moral joins book on Chinese herbal medicine " carries: " lung heat clearing gold, invigorating primordial QI, opens sound, helps biceps." modern medicine study confirms; Radix Codonopsis energy Gastrointestinal motility adjustment, antiulcer, enhancing immunologic function; on excited and suppress two kinds of nervous process to have impact, can raise erythrocyte, hemoglobin, reticulocyte, also have the effect of slow down aging and antioxidation, radioprotective, blood pressure lowering.
Caulis Sinomenii: bitter in the mouth; Pungent; Warm in nature.Return Liver Channel.Expelling wind and removing dampness; Promoting blood circulation and detoxication.Cure mainly rheumatic arthralgia; The arthroncus of knee; Edema; Foot gas; Treating swelling and pain by traumatic injury; Fracture; Deep abscess; Osteomyelitis; Suppurative arthritis; Spondylitis; Sore swollen toxin; Skin pruritus.
Flos Carthami: acrid in the mouth; Warm in nature.Enter liver; Kidney channel.Promoting blood circulation to restore menstrual flow, scattered silt pain relieving.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache." Guizhou medical herbs " carries: " heat-clearing and toxic substances removing, controls innominate toxic swelling, fracture." modern medicine study confirmation, Flos Carthami is improved human body immune function, blood pressure lowering, blood fat reducing, increase coronary flow and the multiple pharmacological effect such as myocardial alimentary blood flow, inhibition thrombosis.
Semen Sinapis Albae: acrid in the mouth; Warm in nature.Enter lung; Liver; Spleen; Stomach; Pericardium channel.Promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain.Control phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation is vomitted, aphasia due to apoplexy, and limbs arthralgia pain is numb, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury." Elementary Medicine ": " sharp chest and diaphragm expectorant, only regurgitation of food from the stomach tells food, gas on phlegmatic cough, aphasia due to apoplexy, appearance yellow skin, settling five organs, stops many urine at night.Control again and flutter damage blood stasis."
Radix Glycyrrhizae: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; Stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, draft is malicious by every means to separate 1,002, is in harmonious proportion from medicine and gains merit." modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; be widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, have anti-gastric-ulcer, gastritis effect in addition.
Fructus Lycii: sweet in the mouth; Property is put down.Return liver; Kidney; Lung meridian.Nourishing the liver; Nourishing kidney; Lung moistening.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual one clear; Soreness of the waist and knees; The expensive essence of sexual impotence; Cough due to consumptive disease; To quench one's thirst taking fluids profusely." book on Chinese herbal medicine just " carries: " improve visual and auditory acuity, adds the solid marrow of essence, strengthen the muscle and bone, and kind benefit impairment caused by overstrain, especially only quenches one's thirst." modern medicine study confirm, Fructus Lycii scalable body's immunity, can effectively Tumor suppression grow and cell mutation, there is the effect of the aspect such as slow down aging, anti-fatty liver, adjusting blood lipid and blood glucose, promotion hemopoietic function.
Radix Morindae Officinalis: acrid-sweet flavor; Warm in nature.Return liver; Kidney channel.Reinforcing the kidney and supporting YANG, strengthening the tendons and bones, expelling wind and removing dampness, cure mainly impotence due to deficiency of the kidney; Seminal emission premature ejaculation; Few abdomen cold type of pain; Incontinence of urine; Cold womb is infertile; Anemofrigid-damp arthralgia; Soreness of the waist and knees; Rheumatism limb gas." Japan hanako materia medica ": settling five organs, centering gas, except all rheumatism, treatment edema.Modern medicine study proves: Radix Morindae Officinalis has puts on weight and antifatigue effect, has a certain impact, can promote Corticosterone secretion, and have blood pressure lowering and antiinflammatory action to immune tool.
Fructus Psoraleae: acrid in the mouth; Bitter; Warm in nature.Return kidney; Pericardium; Spleen; Stomach; Lung meridian.Reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha.Cure mainly: insufficiency of kidney-YANG; Below element deficiency and cold; Chills and pain of the waist and kness; Sexual impotence essence; Frequent micturition; The enuresis; Failure of the kidney in receiving QI; Dyspnea due to deficiency is more than; Asthenia of both the spleen and kidney; Stool chronic diarrhea; Vitiligo; Speckle is bald; Psoriasis." beautiful Chinese catalpa medicine solution ": warm water and soil, digestion diet, rise reach taste, convergence lingering diarrhea, seminal emission, leukorrhagia, drown many, just slide all cards." medical center bun want ": control deficiency and coldness and breathe heavily and cough.Modern medicine study proves: Fructus Psoraleae energy coronary artery dilator, excited heart, improves Heart Pumping Power; Uterus can be shunk and shorten the bleeding time, reducing amount of bleeding; There is estrogen-like effects, vagina keratinization can be strengthened, increase uterus weight; Cause photosensitization, take orally or be coated with skin outward, through daylight or ultraviolet radiation, can localised skin pigmentation be made; Can immunity and endocrine function be strengthened, nervous system regulation function, promote bone marrow hematogenesis; Energy diastole bronchial smooth muscle; In addition hemostasis, antitumor, slow down aging, antibacterial and insecticidal action is still had.
Caulis Bauhihiae Championii: bitter in the mouth; Property is put down; Nontoxic.Return liver; Kidney channel.Expelling wind and removing dampness, promoting flow of QI and blood.Cure mainly rheumatic arthralgia, traumatic injury, hemiplegia, gastric abscess, infantile malnutrition, dysentery." Nanning City's medicine will ": dispel the wind, blood stasis dispelling, dispelling the wind and dampness pathogens osteodynia, traumatic injury synthetism.
Semen Sesami Nigrum: sweet in the mouth; Property is put down.Return liver; Spleen; Kidney channel.Liver and kidney tonifying; The benefit that nourishes blood essence; Loosening bowel to relieve constipation.For dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.Modern medicine study proves: Semen Sesami Nigrum has hypoglycemic activity, short adrenal gland's effect, antiinflammatory action and has certain effect to cardiovascular.
Lignum Sappan: sweet in the mouth; Salty; Property is put down; Nontoxic.GUIXIN; Liver; Stomach; Large intestine channel.Blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain.Cure mainly married woman's amenorrhea due to stagnation of blood, dysmenorrhea, postpartum stagnation cardiac and abdominal pain, puerperal blood faints, carbuncle, traumatic injury, tetanus." book on Chinese herbal medicine is looked for the truth ": Lignum Sappan, function has class Flos Carthami, few with then can and blood, multiplex then can removing blood stasis.But Flos Carthami slightly warm in nature and, then cold nature is also cool for this.Therefore all cause of disease the exterior and the interior wind rises, and hyperamization is stagnant not all right, and puerperal blood faints distension is with extremely, and blood pain abdominal mass due to blood stasis, through holding one's breath the diseases such as heaps soil or fertilizer over and around the roots, carbuncle, injury from falling down, all should the conjunction of phase disease recuperate under medical treatment with his medicine.Modern study proves: Lignum Sappan can increase coronary flow, reduces coronary resistance, reduces heart rate, lowers the work done of left room, but increases myocardial oxygen consumption; Significantly can reduce blood viscosity, the equal highly significant of the effect of Lignum Sappan under various cutting speed; There is antitumaous effect; Also have and suppress AR enzyme inhibition.
Herba Lycopodii: bitter in the mouth; Pungent; Warm in nature.Enter Liver Channel.Expelling wind and removing dampness; Dredge the meridian passage; Reducing swelling and alleviating pain.Cure mainly lumbago, skelalgia of rheumatism; Arthralgia; Traumatic injury; Knife injury; Burn and scald." Hunan medicine will " carries: " relaxing muscles and tendons to promote blood circulation, invigorating qi and dredging collateral.Control lumbago, arthralgia, amenorrhea." modern medicine study shows, Herba Lycopodii contains the alkaloid such as lycopodine, excellent lycoclavanin alkali, and terpenoid, sterol and acids, has cooling, hypotensive activity, can strengthen heart contraction dynamics, excited smooth muscle, also has bacteriostasis in addition.
Radix Cyathulae: sweet in the mouth; Micro-hardship, property is put down.Return liver, kidney channel.Eliminating blood stasis and inducing menstruation; Easing joint movement; Inducing diuresis for treating stranguria syndrome.For amenorrhea lump in the abdomen; Retention of placenta; Arthralgia; Flaccidity of the lower limbs clonic spasm of the muscle; Injury from falling down." Chinese medicinal herbal " carries: " removing blood stasis declines, and controls to beat and flutters knife injury, have the effect relaxing pain." modern medicine study confirmation, Radix Cyathulae has obvious analgesic activity, and contained insectean metamorphosis steroid hormone and Herba Cyathulae Prostratae steroid paulownia have protein assimilation.
Pericarpium Arecae: acrid in the mouth; Slightly warm in nature.Enter spleen; Stomach; Large intestine; Small intestine meridian.Therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO; Line water detumescence.Cure mainly breast abdominal distention vexed; Edema; Foot gas; Dysuria." book on Chinese herbal medicine is new again " carries: " dampness removing chases after wind for eliminating the pathogens from the lung, easing stomach-QI, wide intestinal detumescence, reason waist beriberi, treating malaria disease dysentery." modern medicine study confirms, Pericarpium Arecae can improve intestinal tube tonicity, reduces shrinkage amplitude, has the function regulating intestinal smooth muscle.
Clear Fructus Solani melongenae: acrid in the mouth; Micro-hardship; Warm in nature.Return spleen; Stomach; Kidney channel.Warming middle-JIAO to relieve pain; Promoting flow of QI and blood; Relieving asthma; Diuresis.Cure mainly coldness and pain in the epigastrium; Food stagnation flatulence; Regurgitation is vomitted; Heatstroke is vomited and diarrhoea; Dysentery; Colic of cold type is suffered from abdominal pain; Asthma; Cold-damp dropsy; Dysuria; Turbid urine; Sore swollen toxin; Toothache; Arthralgia due to cold-dampnes; Traumatic injury.Modern medicine study proves: clear Fructus Solani melongenae has antiplatelet aggregative activity, resist myocardial ischemia and myocardial infarction effect, to relieving asthma and anti-allergic effects, antibacterial action and litholytic effect.
The present invention compared with prior art, has following beneficial effect:
The present invention selects medical material, the property of medicine is suitable mutually auxiliary mutually, suit the remedy to the case for the cause of disease, have nourishing the liver nourishing kidney, warming the kidney to activate YANG, invigorating the spleen and replenishing QI, enrich blood invigorate blood circulation, effect of blood circulation promoting and blood stasis dispelling, dispelling cold by warming the meridian, promoting flow of QI and blood, resolving mass and removing the obstruction of the collateral, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to peripheral neuritis cure rate through clinical verification.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
The processing step of process for preparing medicine of the present invention is:
(1) Martin fig, Ramulus Cinnamomi, Radix potentillae anserinae, Herba hypoxis aureae, Fructus Corni, Flos Carthami, Semen Sinapis Albae, Fructus Lycii, Radix Morindae Officinalis, Caulis Bauhihiae Championii, Semen Sesami Nigrum, Lignum Sappan, Pericarpium Arecae are cleaned, dried rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; The water of 4 ~ 6 times amount is added again, heated and boiled 1 ~ 2 hour, immersion after cooling in remaining medicinal residues; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Caulis Trachelospermi, Radix Angelicae Sinensis, Radix seu Caulis Verntilaginis Leiocarpae, Caulis Sinomenii, Herba Lycopodii, Radix Cyathulae are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) put in pot by Rhizoma Atractylodis Macrocephalae sheet and fry with high heat to coke yellow, spray clear water, taking-up is dried, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(4) be placed in the pot of heating by wheat bran, when playing cigarette to pot, add Radix Codonopsis sheet, stir to buff, take out sieve and remove wheat bran, cool, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(5) get clean Radix Morindae Officinalis, mix thoroughly with saline, enter cage and steam thoroughly, pump core, dry, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(6) get clean Fructus Psoraleae saline to mix thoroughly, micro-profit, put in pot to fry with slow fire and heave to micro-, take out, dry, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(7) get clean Radix Glycyrrhizae tabellae, add cooked Mel and a little boiled water, slightly vexed after mixing thoroughly, put in parch container, slow fire is fried to yellow to buff, and take out time tack-free, cool, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(8) by clear Fructus Solani melongenae removing impurity and residual fruit stem, clean, dry, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(9) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), step (6), step (7), step (8), add after refined honey stirs, be prepared as the pill of every 3g.
Usage and dosage: oral, each 2 of every day 3 times, one hour ante cibum took with warm water or warm yellow wine, within 10 days, was 1 course for the treatment of.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection
The routine clinical observation of peripheral neuritis patient 60 selecting my institute to make a definite diagnosis, wherein male 37 example, women 23 example, 42 ~ 64 years old age, 53.7 years old mean age.
2, Therapeutic Method
Patient takes medicine of the present invention, oral, and each 2 of every day 3 times, one hour ante cibum took with warm water or warm yellow wine, within 10 days, was 1 course for the treatment of, took 3 courses for the treatment of.
3, efficacy determination:
(1) cure: numb limbs and tense tendons, send out cool, the clinical symptoms such as pain disappears completely, limbs sensation and motor function recovery normal, physical recovery health.
(2) take a turn for the better: numb limbs and tense tendons, send out cool, the clinical symptoms such as pain obviously alleviates, limbs are felt and motor function obviously makes moderate progress.
(3) invalid: symptom is with treating front no significant difference.
4, result
After Drug therapy of the present invention, patient cures 38 examples, and take a turn for the better 17 examples, invalid 5 examples, cure rate 63.3%, total effective rate 91.6%.Therapeutic outcome shows, Drug therapy peripheral neuritis of the present invention is evident in efficacy, has no side effect, taking convenience, and clinic uses and promotes.
Model case is illustrated:
1, grandson's ××, man, 45 years old.This patient two sufficient toenails stasis of blood is black, paroxysmal pain, and two lower limb are sent out cool, occasionally has numb hand and foot, arm twinge.Coming institute to go to a doctor, being diagnosed as peripheral neuritis, through taking medicine of the present invention, oral, each 2 of every day 3 times, one hour ante cibum took with warm water or warm yellow wine, within 10 days, be 1 course for the treatment of, after taking 2 courses for the treatment of, patient's biped toe melanonychia alleviates, pain disappears, but two lower limb still have and send out symptom cool, follows the doctor's advice after continuing to take 1 course for the treatment of of medicine of the present invention, biped big toe melanonychia disappears, two lower limb such as send out cool at the clinical symptom disappearance, and physical recovery is healthy, fully recovers.
2, what ××, female, 58 years old.Patient's fingers and toes in morning stolidity, stiff, swollen pain, occasionally have acupuncture sample pain, comes institute and go to a doctor, be diagnosed as peripheral neuritis, through taking medicine of the present invention, oral, each 2 of every day 3 times, one hour ante cibum took with warm water or warm yellow wine, within 10 days, was 1 course for the treatment of, after taking 1 course for the treatment of, above-mentioned symptom disappears substantially, and follow the doctor's advice after continuing to take 1 course for the treatment of of medicine of the present invention, above-mentioned symptom disappears completely, physical recovery is healthy, fully recovers.
In sum, medicine of the present invention sums up configuration through Long-term clinical checking to form, in side, the property of medicine of selected Chinese medicine is suitable mutually auxiliary mutually, suit the remedy to the case for the cause of disease, insufficiency of vital energy and blood, cold block, blood vessels are obstructed, QI and blood can not moisten the underlying etiology that foster meridians are primary disease clinical symptoms, therefore selected Chinese medicine is with pungent Wen Weizhu in side, Radix Morindae Officinalis in side, Fructus Psoraleae, Herba hypoxis aureae can warming the kidney to activate YANG; Fructus Corni in side, Fructus Lycii, Semen Sesami Nigrum can nourishing the liver nourishing kidneys; Radix Codonopsis in side, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Radix potentillae anserinae can invigorating the spleen and benefiting QI, enrich blood and invigorate blood circulation; Flos Carthami in side, Lignum Sappan can blood circulation promoting and blood stasis dispelling; Ramulus Cinnamomi in side, Semen Sinapis Albae, clear Fructus Solani melongenae can dispelling cold by warming the meridian, removing obstruction in the collateral to relieve pain; In side, Radix Cyathulae can eliminating blood stasis and inducing menstruation, conducting blood to flow downwards, strengthens activating blood and removing stasis, the strength of relaxing muscles and tendons and activating QI and blood in the collateral simultaneously; In side, the Chinese medicine such as Caulis Trachelospermi, Caulis Sinomenii, Radix seu Caulis Verntilaginis Leiocarpae, Caulis Bauhihiae Championii, Martin fig, Pericarpium Arecae can expelling wind and removing dampness, promoting flow of QI and blood, resolving mass and removing the obstruction of the collateral; In side, Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription; All medicines share and play nourishing the liver nourishing kidney, warming the kidney to activate YANG, invigorating the spleen and replenishing QI altogether, enrich blood invigorate blood circulation, effect of blood circulation promoting and blood stasis dispelling, dispelling cold by warming the meridian, promoting flow of QI and blood, resolving mass and removing the obstruction of the collateral, medicine Jian Lihong, specially heavily attack heresy, removal network is trembled with fear, and QI and blood is unobstructed, and channels is moistened, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to peripheral neuritis cure rate through clinical verification.

Claims (5)

1. be used for the treatment of a medicine pill for peripheral neuritis, it is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
2. a kind of medicine pill being used for the treatment of peripheral neuritis according to claim 1, is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
3. a kind of medicine pill being used for the treatment of peripheral neuritis according to claim 1, is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
4. a kind of medicine pill being used for the treatment of peripheral neuritis according to claim 1, is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
5. be used for the treatment of a preparation method for the medicine pill of peripheral neuritis, it is characterized in that, comprise following processing step:
(1) Martin fig, Ramulus Cinnamomi, Radix potentillae anserinae, Herba hypoxis aureae, Fructus Corni, Flos Carthami, Semen Sinapis Albae, Fructus Lycii, Radix Morindae Officinalis, Caulis Bauhihiae Championii, Semen Sesami Nigrum, Lignum Sappan, Pericarpium Arecae are cleaned, dried rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; The water of 4 ~ 6 times amount is added again, heated and boiled 1 ~ 2 hour, immersion after cooling in remaining medicinal residues; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Caulis Trachelospermi, Radix Angelicae Sinensis, Radix seu Caulis Verntilaginis Leiocarpae, Caulis Sinomenii, Herba Lycopodii, Radix Cyathulae are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) put in pot by Rhizoma Atractylodis Macrocephalae sheet and fry with high heat to coke yellow, spray clear water, taking-up is dried, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(4) be placed in the pot of heating by wheat bran, when playing cigarette to pot, add Radix Codonopsis sheet, stir to buff, take out sieve and remove wheat bran, cool, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(5) get clean Radix Morindae Officinalis, mix thoroughly with saline, enter cage and steam thoroughly, pump core, dry, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(6) get clean Fructus Psoraleae saline to mix thoroughly, micro-profit, put in pot to fry with slow fire and heave to micro-, take out, dry, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(7) get clean Radix Glycyrrhizae tabellae, add cooked Mel and a little boiled water, slightly vexed after mixing thoroughly, put in parch container, slow fire is fried to yellow to buff, and take out time tack-free, cool, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(8) by clear Fructus Solani melongenae removing impurity and residual fruit stem, clean, dry, pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(9) by the thick paste of step (1), step (2) gained, mix with the fine powder of gained in step (3), step (4), step (5), step (6), step (7), step (8), add after refined honey stirs, be prepared as the pill of every 3g.
CN201510835797.1A 2015-11-26 2015-11-26 Traditional Chinese medicine pill for treating peripheral neuritis and preparation method Withdrawn CN105250569A (en)

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