CN104383445A

CN104383445A - Traumatic injury analgesic

Info

Publication number: CN104383445A
Application number: CN201410698304.XA
Authority: CN
Inventors: 王艳萍
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-11-26
Filing date: 2014-11-26
Publication date: 2015-03-04

Abstract

The invention discloses a traumatic injury analgesic. The traumatic injury analgesic is prepared from the following raw materials in parts by weight: 20-30g of sappanwood, 10-20g of safflower, 10-20g of folium artemisiae argyi, 10-20g of musk, 10-20g of nux vomica, 10-20g of dipsacus root, 10-20g of common clubmoss herb, 8-15g of clematis chinensis, 8-12g of caulis sinomenii, 8-12g of cassia twig, 8-12g of garden balsam stem, 8-12g of medicinal cyathula root, 8-12g of peach kernel, 8-12g of liquorice, 8-12g of Chinese rhubarb, 8-12g of radix paeoniae rubra, 8-12g of costustoot, 8-12g of Chinese angelica and 8-12g of curcuma aromatica. Compatibility of medicines is excellent, the effects of promoting circulation and removing stasis, relaxing tendons and activating collaterals, relieving swelling and pain as well as removing stasis and promoting granulation are jointly realized, the traumatic injury analgesic is a better external medicine for treating swelling of the traumatic injury, directly acts on a local part, composition is reasonable, and curative effect is definite; meanwhile, the traumatic injury analgesic is economical and practical, and no side effect is produced, so that the traumatic injury analgesic is worthy of popularization and application.

Description

A kind of traumatic injury analgesic

Technical field

The invention belongs to the field of Chinese medicines, specifically a kind of analgesic of traumatic injury.

Background technology

Traumatic injury is clinical very common, many because of sprain, dampen, fall flutter wound or impact injury, body local subcutaneous soft tissue is caused to tear hemorrhage or ooze out, there is hemorrhage or fracture-dislocation of pain and swelling etc. injury more, clinically to swell and ache, rubescent or livid purple and dysfunction is principal character, its main pathology is that congestion is stopped up stagnant, and blood is held one's breath resistance.

Doctor trained in Western medicine adopts antiinflammatory usually clinically, analgesia treats, but conventional analgesic drug is short for action time, needs repeated multiple times administration, the discomfort that can alleviate swells and ache brings, too much or long period administration, and the symptom such as very easily cause gastrointestinal tract bad.In recent years, we are by utilizing the different pharmacological properties of various medical herbs, traumatic injury affected part is spread on outside the herb mixture developed, the object of reducing swelling and alleviating pain can be obtained, solve again the drawback that oral Chinese medicine effect is slow, bitter to the taste, turn avoid the untoward reaction of taking Western medicine and producing in addition, be directed to swelling and ache that traumatic injury causes and achieve good curative effect.

Summary of the invention

The invention solves at present treatment traumatic injury cause swell and ache in the defect that exists, provide one and can directly act on affected part, local, and determined curative effect, economical and practical, the traumatic injury analgesic of the pure external application of Chinese medicine that has no side effect.

The technical solution adopted in the present invention is:

A kind of traumatic injury analgesic, it is characterized in that, described analgesic is made up of the Chinese herb of following weight portion:

Lignum Sappan 20-30 gram, Flos Carthami 10-20 gram, Folium Artemisiae Argyi 10-20 gram, Moschus 10-20 gram, Semen Strychni 10-20 gram, Radix Dipsaci 10-20 gram, Herba Lycopodii 10-20 gram, Radix Clematidis 8-15 gram, Caulis Sinomenii 8-12 gram, Ramulus Cinnamomi 8-12 gram, Herba speranskiae tuberculatae 8-12 gram, Radix Cyathulae 8-12 gram, Semen Persicae 8-12 gram, Radix Glycyrrhizae 8-12 gram, Radix Et Rhizoma Rhei 8-12 gram, Radix Paeoniae Rubra 8-12 gram, Radix Aucklandiae 8-12 gram, Radix Angelicae Sinensis 8-12 gram, RADIX CURCUMAE 8-12 gram.

As this kind of prioritization scheme:

Described analgesic is made up of the Chinese herb of following weight portion:

Lignum Sappan 20 grams, 10 grams, Flos Carthami, Folium Artemisiae Argyi 10 grams, 10 grams, Moschus, Semen Strychni 10 grams, Radix Dipsaci 10 grams, Herba Lycopodii 10 grams, Radix Clematidis 8 grams, Caulis Sinomenii 8 grams, Ramulus Cinnamomi 8 grams, Herba speranskiae tuberculatae 8 grams, Radix Cyathulae 8 grams, 8 grams, Semen Persicae, 8 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 8 grams, Radix Paeoniae Rubra 8 grams, the Radix Aucklandiae 8 grams, Radix Angelicae Sinensis 8 grams, RADIX CURCUMAE 8 grams.

As this kind of prioritization scheme:

Described analgesic is made up of the Chinese herb of following weight portion:

Lignum Sappan 25 grams, 15 grams, Flos Carthami, Folium Artemisiae Argyi 15 grams, 15 grams, Moschus, Semen Strychni 15 grams, Radix Dipsaci 15 grams, Herba Lycopodii 15 grams, Radix Clematidis 12 grams, Caulis Sinomenii 10 grams, Ramulus Cinnamomi 10 grams, Herba speranskiae tuberculatae 10 grams, Radix Cyathulae 10 grams, 10 grams, Semen Persicae, 10 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 grams, Radix Paeoniae Rubra 10 grams, the Radix Aucklandiae 10 grams, Radix Angelicae Sinensis 10 grams, RADIX CURCUMAE 10 grams.

As this kind of prioritization scheme:

Described analgesic is made up of the Chinese herb of following weight portion:

Lignum Sappan 30 grams, 20 grams, Flos Carthami, Folium Artemisiae Argyi 20 grams, 20 grams, Moschus, Semen Strychni 20 grams, Radix Dipsaci 20 grams, Herba Lycopodii 20 grams, Radix Clematidis 15 grams, Caulis Sinomenii 12 grams, Ramulus Cinnamomi 12 grams, Herba speranskiae tuberculatae 12 grams, Radix Cyathulae 12 grams, 12 grams, Semen Persicae, 12 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 12 grams, Radix Paeoniae Rubra 12 grams, the Radix Aucklandiae 12 grams, Radix Angelicae Sinensis 12 grams, RADIX CURCUMAE 12 grams.

The instructions of taking of said medicine is: dried by the raw material Chinese medicine of above-mentioned weight proportion and be crushed into powder.Before the drug of topical application, assisting patients uses warm water cleaning affected part, dries moisture.Indivedual fracture has slight displacement person, must fix through doctor's manual reduction, then according to injury size, get appropriate Chinese medicinal powder warm water and proper honey fully stirs into pasty state, be coated on affected part equably, thickness is 0.3 ~ 0.5mm about, after expanding 1 ~ 2cm again according to the livid purple scope of affected part pain and swelling, covering with hospital gauze is fixed on skin, and drug of topical application every day once.

The raw material Chinese medicine of said medicine:

Lignum Sappan, sweet in the mouth, salty, property is put down; GUIXIN, liver, stomach, large intestine channel.There is promote blood circulation to disperse blood clot, effect of reducing swelling and alleviating pain.

Flos Carthami, acrid in the mouth, warm in nature; GUIXIN, Liver Channel.There is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.

Folium Artemisiae Argyi, bitter in the mouth, pungent, warm in nature; Return spleen, liver, kidney channel.There is vital energy regualting and blood circulation-promoting, by cold damp eliminating, effect of warming the meridian for stopping bleeding.

Moschus, acrid in the mouth, warm in nature.GUIXIN, spleen channel.There is refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, effect of reducing swelling and alleviating pain.

Semen Strychni, bitter in the mouth, cold in nature; Return liver, spleen channel.There is mass dissipating and swelling eliminating, effect of removing obstruction in the collateral to relieve pain.

Radix Dipsaci, bitter in the mouth, pungent, slightly warm in nature; Return liver, kidney channel.There is invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous injured, effect of only metrorrhagia.

Herba Lycopodii, bitter in the mouth, pungent, warm in nature; Return Liver Channel.There is expelling wind and removing dampness, effect of relaxing muscles and tendons and activating QI and blood in the collateral.

Radix Clematidis is acrid in the mouth, salty, warm in nature; Return urinary bladder channel.There is wind-damp dispelling, the meridian dredging, effect of stopping numbness pain.

Caulis Sinomenii, bitter in the mouth, pungent, property is put down; Return liver, spleen channel.There is expelling wind and removing dampness, effect of inducing diuresis to remove edema.

Ramulus Cinnamomi, acrid in the mouth, sweet, warm in nature; GUIXIN, spleen, urinary bladder channel.There is expelling pathogenic factors from muscles by diaphoresis, warming the meridian for promoting the flow of YANG QI, effect of expelling wind and removing dampness.

Herba speranskiae tuberculatae, sweet in the mouth, pungent, warm in nature; Return liver, kidney channel.Have relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and dampness, promoting blood circulation and stopping pain, softening the hard mass disappears effect of painful abdominal mass.

Radix Cyathulae, bitter in the mouth, acid, property is put down; Return liver, kidney channel.There is nourishing the liver and kidney, bone and muscle strengthening, blood circulation promoting and blood stasis dispelling, effect of inducing diuresis for treating stranguria syndrome.

Semen Persicae, sweet in the mouth, hardship, property is put down; Return lung, liver, large intestine channel.There is blood circulation promoting and blood stasis dispelling, moisturize effect of laxation.

Radix Glycyrrhizae, sweet in the mouth, property is put down; GUIXIN, spleen, lung, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription

Radix Et Rhizoma Rhei, bitter in the mouth, cold in nature; Return spleen, stomach, large intestine, liver, pericardium channel.There is heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, effect of blood circulation promoting and blood stasis dispelling.

Radix Paeoniae Rubra, bitter in the mouth, cold in nature; Return Liver Channel.There is clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, effect of reducing swelling and alleviating pain.

The Radix Aucklandiae, acrid in the mouth, hardship, warm in nature; Return spleen, stomach, lung meridian.There are promoting the circulation of QI to relieve pain, effect of intestinal stasis relieving in tune.

Radix Angelicae Sinensis, acrid in the mouth, warm in nature; Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, effect of pain relieving intestine moistening.

RADIX CURCUMAE, acrid in the mouth, hardship, cold in nature; GUIXIN, liver, gallbladder meridian.There is promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clearing away heat and cooling blood, removing heat from the heart to restore the consciousness, effect of dampness removing jaundice eliminating.

Chinese medicine thinks that the main pathology of traumatic injury is hemorrhage, and blood stasis is stopped up stagnant, and blood is held one's breath resistance, stagnation of QI and blood may bring about pain, the process of the process of its healing and blood stasis removing, new life.Therefore treatment is when being good for flesh, reducing swelling and alleviating pain for rule for the treatment of with blood circulation promoting and blood stasis dispelling, spleen reinforcing.

In external application of Chinese medicine medicine of the present invention, Lignum Sappan, Flos Carthami, Folium Artemisiae Argyi, Moschus, Semen Strychni, the Radix Aucklandiae can promote blood circulation to disperse blood clot, promoting of the circulation of QI and removing the obstruction in the collaterals, reducing swelling and alleviating pain; Radix Dipsaci, Radix Cyathulae, Radix Angelicae Sinensis energy promoting blood circulation to remove obstruction in the collateral, bone and muscle strengthening, draw blood enter through, promote cellular metabolism and skin growth; Herba Lycopodii, Radix Clematidis, Caulis Sinomenii, Ramulus Cinnamomi, Herba speranskiae tuberculatae energy remove rheumatism, warming the meridian for promoting the flow of YANG QI, relaxing muscles and tendons and activating QI and blood in the collateral, improves body blood circulation; Semen Persicae, Radix Et Rhizoma Rhei, Radix Paeoniae Rubra, RADIX CURCUMAE can clearing away heat-fires, removing pathogenic heat from blood and toxic substance from the body, and circulation of qi promoting is sensible; Radix Glycyrrhizae heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, drug effect to play maximum.All medicine compatibilities are superior, play blood circulation promoting and blood stasis dispelling altogether, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain, effect of blood stasis removing granulation promoting, use collaterals of human conduction principle, medicine is directly applied to traumatic injury affected part, makes medicine arrive rapidly position, affected part, blood vessels, blood circulation promoting can be got through at short notice, and then remove affected part blood stasis, repair damaged joints and soft tissue position; Body cell vigor can also be strengthened simultaneously, improve human body physiological defense ability, not only take stopgap measures but also effect a permanent cure, thus reach the object of thoroughly curing traumatic injury.

For investigating the clinical efficacy of medicine of the present invention further, we have selected 100 routine traumatic injury out-patients and carry out clinical trial, wherein male 61 example, women 39 example, oldest 71 years old, minimum 24 years old, 48 years old mean age; All see that the subcutaneous livid purple ecchymosis in affected part is obviously accompanied to swell and ache, some deformities are obviously with functional activity obstacle; Patient is divided at random two groups to contrast, treatment group 50 example, each 25 examples of men and women, 47.6 years old mean age; Matched group 50 example, man 26 example, female 24 example, 48.2 years old mean age; Two groups of patients, in sex, age, disease etc., compare there was no significant difference (P > 0.05) through statistics, have comparability.

Therapeutic Method:

Treatment group: get Lignum Sappan 25 grams, 15 grams, Flos Carthami, Folium Artemisiae Argyi 15 grams, 15 grams, Moschus, Semen Strychni 15 grams, Radix Dipsaci 15 grams, Herba Lycopodii 15 grams, Radix Clematidis 12 grams, Caulis Sinomenii 10 grams, Ramulus Cinnamomi 10 grams, Herba speranskiae tuberculatae 10 grams, Radix Cyathulae 10 grams, 10 grams, Semen Persicae, 10 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 grams, Radix Paeoniae Rubra 10 grams, the Radix Aucklandiae 10 grams, Radix Angelicae Sinensis 10 grams, RADIX CURCUMAE 10 grams, oven dry is crushed into powder.Before the drug of topical application, assisting patients uses warm water cleaning affected part, dries moisture.Indivedual fracture has slight displacement person, must fix through doctor's manual reduction, then according to injury size, get appropriate Chinese medicinal powder warm water and proper honey fully stirs into pasty state, be coated on affected part equably, thickness is 0.3 ~ 0.5mm about, after expanding 1 ~ 2cm again according to the livid purple scope of affected part pain and swelling, covering with hospital gauze is fixed on skin, and drug of topical application every day once.Matched group adopts Pingyue County to open up muscle tincture, and (Luoyang, henan bonesetting hospital produces, and authentication code: Henan medicine word 204030027, product batch number: 20060801), dosage form is spray.Specification every bottle 200ml.Every spray 3 times, gives suitable massage.

Criterion of therapeutical effect:

Cure: clinical symptoms disappears completely, and without pain and swelling, activity is not limited;

Effective: pain obviously alleviates, activity is still limited;

Effective: pain is slightly alleviated, movable without improving;

Invalid: clinical symptoms is without alleviation.

Efficacy result:

1. Clinical efficacy comparison:

After treatment, treatment group cures 38 examples, effective 6 examples, effective 3 examples, invalid 3 examples, and cure rate is 76.0%, and total effective rate reaches 94.0%; Matched group cures 21 examples, effective 5 examples, effective 13 examples, invalid 11 examples, and cure rate is 42.0%, and total effective rate is 78.0%; The symptoms such as treatment group local pain, swelling, tenderness, improving action are obviously better than matched group, and two groups of results compare P < 0.05, and difference has statistical significance.Detailed results is in table 1.

Table 1: the curative effect comparision result table after two groups of case treatments

Group	Number of cases	Cure n (%)	Effective n (%)	Effective n (%)	Invalid n (%)	Total effective rate (%)
							Treatment group	50	38(76.0)	6(12.0)	3(6.0)	3(6.0)	94.0
Matched group	50	21(42.0)	5(10.0)	13(26.0)	11(22.0)	78.0

2. untoward reaction is compared

In therapeutic process, there is gastrointestinal upset patient 6 example in matched group, treatment group has no obvious adverse reaction.

Result shows, the present invention's pure external application of Chinese medicine medicine is the external used medicine that a kind of good treatment traumatic injury swells and ache, and it directly acts on local, reasonable recipe, determined curative effect, and economical and practical, has no side effect, clinic promotion and application.

Detailed description of the invention

Embodiment 1: a kind of traumatic injury analgesic, chooses Lignum Sappan 20 grams, 10 grams, Flos Carthami, Folium Artemisiae Argyi 10 grams, 10 grams, Moschus, Semen Strychni 10 grams, Radix Dipsaci 10 grams, Herba Lycopodii 10 grams, Radix Clematidis 8 grams, Caulis Sinomenii 8 grams, Ramulus Cinnamomi 8 grams, Herba speranskiae tuberculatae 8 grams, Radix Cyathulae 8 grams, 8 grams, Semen Persicae, 8 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 8 grams, Radix Paeoniae Rubra 8 grams, the Radix Aucklandiae 8 grams, Radix Angelicae Sinensis 8 grams, RADIX CURCUMAE 8 grams.

Embodiment 2: a kind of traumatic injury analgesic, chooses Lignum Sappan 25 grams, 15 grams, Flos Carthami, Folium Artemisiae Argyi 15 grams, 15 grams, Moschus, Semen Strychni 15 grams, Radix Dipsaci 15 grams, Herba Lycopodii 15 grams, Radix Clematidis 12 grams, Caulis Sinomenii 10 grams, Ramulus Cinnamomi 10 grams, Herba speranskiae tuberculatae 10 grams, Radix Cyathulae 10 grams, 10 grams, Semen Persicae, 10 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 grams, Radix Paeoniae Rubra 10 grams, the Radix Aucklandiae 10 grams, Radix Angelicae Sinensis 10 grams, RADIX CURCUMAE 10 grams.

Embodiment 3: a kind of traumatic injury analgesic, chooses Lignum Sappan 30 grams, 20 grams, Flos Carthami, Folium Artemisiae Argyi 20 grams, 20 grams, Moschus, Semen Strychni 20 grams, Radix Dipsaci 20 grams, Herba Lycopodii 20 grams, Radix Clematidis 15 grams, Caulis Sinomenii 12 grams, Ramulus Cinnamomi 12 grams, Herba speranskiae tuberculatae 12 grams, Radix Cyathulae 12 grams, 12 grams, Semen Persicae, 12 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 12 grams, Radix Paeoniae Rubra 12 grams, the Radix Aucklandiae 12 grams, Radix Angelicae Sinensis 12 grams, RADIX CURCUMAE 12 grams.

Below by concrete case, curative effect of medication of the present invention is verified further:

Case 1

Grandson, man, 45 years old.Patient due to hands scrap old television set go downstairs time, left foot is stepped on empty landing in varus posture and is sprained.Outer swollen ankles, subcutaneous extvavasated blood, tenderness is obvious, ankle moving function limitation.With our medicine hot compress in affected part after 1 day, swelling pain obviously alleviates, and after deposited 4 days, swelling is disappeared, and pain is eliminated, and blood stasis disappears, and patient activity recovers normal, and patient cures.

Case 2

Yuan, man, 25 years old.Patient is because accidentally spraining left ankle joint during Basketball Match, and pain at that time, swelling is obvious, and moving obstacle, only can adhere to slow limping, through wiping local outward by BOGU SHUI, has no positive effect.Left sprained ankle is diagnosed during people institute.Then upon somebody's introduction, utilize our external application for curing, after the drug of topical application three doses, swollen swelling is disappeared, pain relief; Medication 3 days again, swelling, pain disappears, and functional rehabilitation is normal.

Case 3

Season, female, 34 years old.Patient falls because rainy day hill path road is sliding, and right sprained ankle, produces severe pain at once, difficulty of walking, and ankle swelling, Surrounding muscles is nervous.Check without percussion pain and sprain.Utilize SHEXIANG ZHUANGGU GAO to have no positive effect after one week, so use we's treatment instead, the drug of topical application is after 2 days, and swelling and pain obviously alleviate, and continue medication after 5 days, pain and swelling disappears completely, and freely, patient cures in activity.

Claims

1. a traumatic injury analgesic, is characterized in that, described analgesic is made up of the Chinese herb of following weight portion:

2. analgesic according to claim 1, is characterized in that, described analgesic is made up of the Chinese herb of following weight portion:

3. analgesic according to claim 1, is characterized in that, described analgesic is made up of the Chinese herb of following weight portion:

4. analgesic according to claim 1, is characterized in that, described analgesic is made up of the Chinese herb of following weight portion: