CN104189431A - Lymphatic tuberculosis calming liver and clearing heat preparation and preparation method thereof - Google Patents
Lymphatic tuberculosis calming liver and clearing heat preparation and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a lymphatic tuberculosis Chinese herba preparation for calming liver and clearing heat. The preparation is prepared by the following main raw material in part by weight: 5 to 12 parts of gleditschia horrida wood veneer, 6 to 15 parts of bulb of ussuri fritillary, 3 to 9 parts of platycodon root, 10 to 20 parts of red sage root, 6 to 10 parts of scutellarta root, 8 to 12 parts of cyperirhizome, 6 to 9 parts of annual fleabane, 6 to 15 parts of fleece-flower root, 8 to 12 parts of Aristolochia kwangsiensis Chun et How, 15 to 25 parts of selfheal spike, 6 to 12 parts of forsythia fruit, 0.5 to 1.5 parts of purple sal-ammoniac, and 8 to 16 parts of buttercup root. The Chinese herba preparation is simple to operate, low in drug cost, low in side effect and high in cure rate.
Description
Technical field
The invention discloses a kind of Chinese medicine preparation, especially lymphoid tuberculosis calming liver and clearing heat preparation and method for making, belong to Chinese medicine field.
Background technology
Lymphoid tuberculosis, the traditional Chinese medical science is referred to as scrofula, is the malicious block organization that is embodied in flesh table, is that the scorchingly hot poison cohesion of the expectorant institute by liver lung two aspects is become.Doctor trained in Western medicine refers to, thereby specialize in human body in detoxicating virus killing, protects blood vessel, and the lymphsystem of tissue, meets with outside ex vivo and cannot remove the toadstool of killing, and condenses and assemble the malignant tumor of Yu Ji table organization formation.Scrofulous symptom is many grows pimple in cervical region one side or bilateral, grows up gradually, superficial, push slip, without obvious tenderness, increase gradually as low in passive protective physical fitness, skin is sent out purpling, and final ulceration flowing water sample pus is also discharged the cheesy pus of yellow turbid sample, and the traditional Chinese medical science is referred to as meaning " lymphoid tuberculosis ".Repeatedly fester few, the whole body poisoning symptom such as part patient can have low grade fever, robber, antiperspirant inappetence, become thin.
Publication No. CN 102188615 A(application numbers 201110111758.9) Chinese patent literature discloses a kind of scrofulous method for the treatment of, this medicine is comprised of Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati, Pseudobulbus Cremastrae Seu Pleiones, Thallus Laminariae (Thallus Eckloniae), Sargassum, Radix Scrophulariae, Radix Angelicae Sinensis, the Radix Astragali, Pericarpium Citri Reticulatae, Semen Sinapis Albae, Scolopendra, Scorpio, and its weight proportion is 2: 2: 2: 1: 1: 1: 2: 1: 1: 1: 1: 1: 1.Publication No. CN 103845582 A(application number 201210532573.X) Chinese patent literature discloses a kind of scrofulous Chinese medicine for the treatment of, and the crude drug of making effective ingredient by following weight is: Semen Ricini 30-50 gram, Tremella 6-10 gram, Bulbus Allii Fistulosi 20-24 gram.Publication No. CN 101700292 A(application numbers 200910234938.9) Chinese patent literature discloses a kind of scrofulous Chinese medicine composition for the treatment of, and consists of: Mylabris, Cinnabaris, Borneolum Syntheticum, Radix orixae japonicae, Fructus Crotonis, Semen Persicae following bulk drugs.
In a word, present antituberculotics is mostly difficult to penetrate pathological tissues and reaches effective bacteriocidal concentration, can not suppress fast and effectively disease, there is the untoward reaction such as liver function injury in some patient also, make Drug therapy failure, the preparation of lymphoid tuberculosis calming liver and clearing heat of the present invention can improve existing unfavorable situation.
Summary of the invention
Not enough for prior art, the object of this invention is to provide a kind of Chinese medicine preparation for the treatment of lymphoid tuberculosis calming liver and clearing heat, there is feature simple to operate, evident in efficacy, and its adopts comparatively common Chinese crude drug with low cost, without financial burden.
Technical scheme of the present invention is:
Lymphoid tuberculosis calming liver and clearing heat preparation, the main raw material(s) that takes off row weight proportion is prepared from: Fructus Gleditsia veneer 5-12 part; Bulbus Fritillariae Ussuriensis 6-15 part; Radix Platycodonis 3-9 part; Radix Salviae Miltiorrhizae 10-20 part; Radix Scutellariae 6-10 part; Rhizoma Cyperi 8-12 part; Herba Erigerontis Annui 6-9 part; Radix Polygoni Multiflori 6-15 part; DABAIJIE potato 8-12 part; Spica Prunellae 15-25 part; Fructus Forsythiae 6-12 part; Sal Ammoniacus 0.5-1.5 part; Radix Ranunculi Ternati 8-16 part.
Preferred version is: Fructus Gleditsia veneer 7-10 part; Bulbus Fritillariae Ussuriensis 9-12 part; Radix Platycodonis 5-7 part; Radix Salviae Miltiorrhizae 12-18 part; Radix Scutellariae 7-9 part; Rhizoma Cyperi 9-11 part; Herba Erigerontis Annui 7-8 part; Radix Polygoni Multiflori 8-13 part; DABAIJIE potato 9-11 part; Spica Prunellae 18-22 part; Fructus Forsythiae 8-10 part; Sal Ammoniacus 0.7-1.3 part; Radix Ranunculi Ternati 10-14 part.
Be more preferably 8.5 parts of Fructus Gleditsia veneer; 10.5 parts of Bulbus Fritillariae Ussuriensiss; 6 parts of Radix Platycodoniss; 15 parts of Radix Salviae Miltiorrhizaes; 8 parts of Radix Scutellariaes; 10 parts of Rhizoma Cyperis; 7.5 parts of Herba Erigerontis Annuis; 10.5 parts of Radix Polygoni Multiflori; 10 parts of DABAIJIE potatos; 20 parts of Spica Prunellaes; 9 parts of Fructus Forsythiaes; 1 part of Sal Ammoniacus; 12 parts of Radix Ranunculi Ternatis.
The present invention also provides this Chinese medicine preparation has been made to pharmaceutically acceptable decoction, powder, pill and thick paste agent.
The preparation method of described decoction is as follows:
1. get Sal Ammoniacus, thermokalite water soaking 40-60 minute (preferably 50 minutes) with 2%, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, adding water did not have medical material 2-4cm to soak 20-30 minute (preferably 25 minutes), intense fire is fried open and turns slow fire boiling 30-40 minute (preferably 35 minutes), and filtered while hot obtains medicinal liquid;
4. recrement adds water continuation decoction, and after boiling, the persistent period is 20-30 minute (preferably 25 minutes), obtains medicinal liquid after filtration;
5. by step 1. 2. in gained medicated powder, cross 100-120 mesh sieve (preferably 110 orders), with step 3. 4. gained medicinal liquid mix homogeneously, sterile packaged obtains Chinese medicine decoction.
The preparation method of described Chinese medicine decoction, it is 4 times of medical material weight that step adds clear water amount in 4..
The preparation process of described powder is as follows:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, the micro-stir-fry of slow fire 5-10 minute (preferably 7 minutes), takes out and puts into mortar, carefully pulverizes;
4. above-mentioned gained fine powder is mixed, cross 100-120 mesh sieve (preferably 110 orders), according to the specification of 5g/ bag, make powder.
The preparation process of described pill is as follows:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, the micro-stir-fry of slow fire 5-10 minute (preferably 7 minutes), takes out and puts into mortar, carefully pulverizes;
4. above-mentioned gained fine powder is crossed to 110 mesh sieves and starch mixes, ratio is 2:1, adds the general ball of making of water, obtains pill.
The preparation method of described thick paste agent:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, the micro-stir-fry of slow fire 8 minutes, takes out and puts into mortar, carefully pulverizes;
3. above-mentioned gained fine powder is put into bag filter, add the water of 7 times of medical material weight, intense fire is fried open, and slow fire boiling 50 minutes, removes medicinal residues, and residue medicinal liquid continues boiling, to medicine liquid volume simmer down to original 1/5;
4. by step 3. gained concentrated solution mix in the ratio of 1:1 with Mel, stir and obtain thick paste agent.
The application of Chinese medicine preparation described in the present invention also provides when the scrofulous medicine of preparation treatment.
The pharmacological effect of each crude drug is respectively:
Fructus Gleditsia veneer: base is former: root bark or peel of stem by deciduous tree Fructus Gleditsia are used as medicine, and autumn and winter gather, and section is dried.Nature and flavor with return through acrid in the mouth, warm in nature, nontoxic.There are the effects such as detoxicating and resolving stagnation of pathogens, wind dispelling insecticide.Cure mainly innominate toxic swelling, scabies, malignant boil, lymphoid tuberculosis, rheumatic ostalgia etc.
Bulbus Fritillariae Ussuriensis: base is former: be the bulb of Liliaceae Fritillaria Linn Bulbus Fritillariae Ussuriensis.Composition: bulb contains alkaloid: imperialine-3-β-D-Glucose glycosides, peimisine, imperialine, pingpeimine A, flat shellfish alkali second, flat shellfish alkali third and flat shellfish alkali glycosides.Nature and flavor with return through: bitter, sweet, be slightly cold.Return lung, heart channel.There are clearing heat and moistening lung, the effect of preventing phlegm from forming and stopping coughing.For lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, cough with blood-flecked phlegm.
Radix Platycodonis: nature and flavor: bitter, pungent, flat.Gui Jing: return lung meridian.Effect: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.Cure mainly: for cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Radix Salviae Miltiorrhizae: nature and flavor are bitter, cold nature.Energy blood circulation promoting and blood stasis dispelling, removing heat from blood, calms the nerves.Enter the heart, spleen two warps.According to the < < book on Chinese herbal medicine > > that looks for the truth: Radix Salviae Miltiorrhizae has the effect into percardium removing blood stasis with potent drugs.Modern medicine study confirms, its energy coronary artery dilator, and increase coronary flow, improves myocardial ischemia, infraction and cardiac function, regulates the rhythm of the heart, and can expand peripheral blood vessel, improves microcirculation; Can improve body's hypoxia tolerance; There is anticoagulation, promote fibrinolytic, suppress platelet aggregation, suppress thrombotic effect; Can reduce blood fat, suppress coronary atherosclerosis and form; Can shorten the convalescent period of erythrocyte and hematochrome, Reticulocyte is increased, can promote the reparation of tissue, accelerate the healing of fracture; There is nervus centralis to have inhibitory action; There is antitumor action; Energy enhancing human body immunity function; Can reduce blood glucose; The various bacteria such as tubercule bacillus are had to inhibitory action.
Radix Scutellariae: bitter in the mouth, cold in nature, return lung, gallbladder, spleen, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect.For hygropyrexia, heat-damp in summer, vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Rhizoma Cyperi: nature and flavor with return through pungent, micro-hardship, micro-sweet, flat.Return liver, spleen, tri-jiao channel.There is dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, the effect of menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, distending pain in the chest and hypochondrium, hernia pain, distending pain of the breast, stagnation of QI in spleen and stomach, gastral cavity abdomen painful abdominal mass is vexed, distension pain, menoxenia, amenorrhea dysmenorrhea.
Herba Erigerontis Annui: base is former: be the herb of feverfew Herba Erigerontis Annui.Nature and flavor with return through: property is sweet, bitter, cool, returns stomach, large intestine channel.There is the antidiarrheal of helping digestion, heat-clearing and toxic substances removing, the effect of preventing the attack (or recurrence) of malaria.Cure mainly dyspepsia, gastroenteritis, gingivitis, malaria, venom.
Radix Polygoni Multiflori: nature and flavor with return through: bitter, sweet, puckery, tepor.Return liver, the heart, kidney channel.There is removing toxic substances, eliminating carbuncle, preventing the attack (or recurrence) of malaria, the effect of loosening bowel to relieve constipation.For carbuncle sore, scrofula, rubella pruritus, chronic malaria body is empty, dryness of the intestine constipation.
DABAIJIE potato: base is former: be the tuber of Aristolochiaceae birthwort kwangsi dutchmanspipe root.Composition: root contains allantoin, aristolochic acid A ,-sitosterol, 6-methoxyl group removes nitro Aristolochic Acid methanol and 6-methoxyl group aristolochic acid A methyl ester, the alkaloids such as magnoflorine.The property of medicine: hardship, cold.GUIXIN, stomach, large intestine channel.Function cures mainly: regulating QI to relieve pain, heat-clearing and toxic substances removing, hemostasis.Cure mainly spastic stomachache, stomachache, acute gastroenteritis, gastric and duodenal ulcers, dysentery, traumatic injury, sore and toxic, venom, bone tuberculosis, traumatic hemorrhage.
Spica Prunellae: nature and flavor with return through: pungent, bitter, cold.Return liver, gallbladder meridian.There is purging liver-fire, improving eyesight, the effect of mass dissipating and swelling eliminating.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, acute mastitis, nodules of the breast, distending pain of the breast.
Fructus Forsythiae: nature and flavor with return through: hardship, is slightly cold.Return lung, the heart, small intestine meridian; There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the effect of dispelling wind and heat pathogens; For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm people battalion, high hot excessive thirst, coma is sent out speckle, the puckery pain of pyretic stranguria.
Sal Ammoniacus: base is former: be halogenide class mineral violet color rock salt crystal.Composition: main sodium chloride-containing; Still containing a small amount of Fe
3+, Fe
2+, Mg
2+, S
2-deng.The property of medicine: salty, bitter, pungent, warm in nature.Poisonous.Attach to the lung and stomach meridians.Function cures mainly: removing blood stasis with potent drugs removing food stagnancy, softening the hard mass erosion is rotten.Zhu Zhi lumps in the chest and abdomen, dysphagia and regurgitation, breath raw meat, sore throat corneal nebula, carbuncle scrofula, malignant boil wart.
Radix Ranunculi Ternati: nature and flavor with return through sweet, acrid, warm.Return liver, lung meridian.There is dissipating phlegm and resolving masses, the effect of removing toxic substances and promoting subsidence of swelling.For scrofula sucutaneous nodule, furuncle swelling toxin, snake bite and insect sting.
Chinese medicine composition prescription science provided by the invention, the preparation method of various dosage forms is simple, products obtained therefrom taking convenience, in addition, excellent results of the present invention also shows:
1, gained preparation of the present invention is simple to operate, medical material is with low cost, it is painful little to take;
2, this prescription Chinese crude drug used is Chinese medicine, and side effect is little, and cure rate is high;
3, for lymph tuberculosis, the relief of symptoms of suiting the remedy to the case, improves liver function, is applicable to the crowd of each age group.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1the Chinese medicine preparation of lymphoid tuberculosis calming liver and clearing heat, is prepared from by following bulk drugs: Fructus Gleditsia veneer 5g, Bulbus Fritillariae Ussuriensis 6g, Radix Platycodonis 3g, Radix Salviae Miltiorrhizae 10g, Radix Scutellariae 6g, Rhizoma Cyperi 8g, Herba Erigerontis Annui 6g, Radix Polygoni Multiflori 6g, DABAIJIE potato 8g, Spica Prunellae 15g, Fructus Forsythiae 6g, Sal Ammoniacus 0.5g, Radix Ranunculi Ternati 8 g.The preparation method of the Chinese medicine decoction of above-mentioned treatment lymphoid tuberculosis calming liver and clearing heat:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, add water and do not have medical material 2-4cm to soak 20 minutes, intense fire is fried open and turns slow fire boiling 30 minutes, and filtered while hot obtains medicinal liquid;
4. recrement adds water continuation decoction, and the water yield is 4 times of medical material weight, and after boiling, the persistent period is 20 minutes, obtains medicinal liquid after filtration;
5. by step 1. 2. in gained medicated powder, cross 100 mesh sieves, with step 3. 4. gained medicinal liquid mix homogeneously, sterile packaged obtains Chinese medicine decoction.
The instructions of taking of decoction of the present invention: take twice (warm) each 150-200m1,7 days courses for the treatment of every day.
embodiment 2
The Chinese medicine preparation of lymphoid tuberculosis calming liver and clearing heat, is prepared from by following bulk drugs: pod veneer 12g, Bulbus Fritillariae Ussuriensis 15g, Radix Platycodonis 9g, Radix Salviae Miltiorrhizae 20g, Radix Scutellariae 10g, Rhizoma Cyperi 12g, Herba Erigerontis Annui 9g, Radix Polygoni Multiflori 15g, DABAIJIE potato 12g, Spica Prunellae 25g, Fructus Forsythiae 12g, Sal Ammoniacus 1.5g, Radix Ranunculi Ternati 16g.The preparation method of the Chinese powder medicine of above-mentioned treatment lymphoid tuberculosis calming liver and clearing heat:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, the micro-stir-fry of slow fire 5-10 minute (preferably 7 minutes), takes out and puts into mortar, carefully pulverizes;
4. above-mentioned gained fine powder is mixed, cross 100-120 mesh sieve (preferably 110 orders), according to the specification of 5g/ bag, make powder.
Instructions of taking: every day 2-3 time, each one bag, with warm boiled water, 7 days courses for the treatment of.
Model case: xxx, the age: 11 years old; Sex: man; Medical history: suffer from lymphoid tuberculosis 1 year, cervical region has lump, is fused into agglomerate when serious, and quality moderate is hard, and with the symptom of fever, midnight night sweat.Once use antibiotic invalid, caused slight liver dysfunction.
Take this example gained Chinese powder medicine, each one bag every day three times, seven days is a course for the treatment of.Patient took after 7 days, fever, night sweat transference cure, and neck region lump has the sign of disappearing, and continues to use two courses for the treatment of, and lump deliquescing also fades away, and through examination in hospital, liver function is also recovered normally, patient's recovery from illness.
embodiment 3
The Chinese medicine preparation of lymphoid tuberculosis calming liver and clearing heat, is prepared from by following bulk drugs: Fructus Gleditsia veneer 7g, Bulbus Fritillariae Ussuriensis 9g, Radix Platycodonis 5g, Radix Salviae Miltiorrhizae 12g, Radix Scutellariae 7g, Rhizoma Cyperi 9g, Herba Erigerontis Annui 7g, Radix Polygoni Multiflori 8g, DABAIJIE potato 9g, Spica Prunellae 18g, Fructus Forsythiae 8g, Sal Ammoniacus 0.7g, Radix Ranunculi Ternati 10g.The medicine pill preparation method for the treatment of lymphoid tuberculosis calming liver and clearing heat is:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, the micro-stir-fry of slow fire 5-10 minute (preferably 7 minutes), takes out and puts into mortar, carefully pulverizes;
4. above-mentioned gained fine powder is crossed to 110 mesh sieves and starch mixes, ratio is 2:1, adds the general ball of making of water, obtains pill.
Instructions of taking: each ball, every day three times, warm boiled water, 7 days is a course for the treatment of.
Model case: xxx, the age: 18 years old; Sex: man; Medical history: right ear side occurs an enclosed mass without obvious inducement, increases gradually after two months, with tenderness, the tolerance of health declines, and stomach significant discomfort is diagnosed as lymphoid tuberculosis through puncture, take a period of time Western medicine, effect is remarkable and occur abnormal liver function, and time-out is taken antituberculotics.
Take this example gained medicine pill, every day three times, each ball, warm boiled water, seven days is a course for the treatment of.Use 14 days, patient's lump has obviously and dwindles, and pain is lighter, continues to take two courses for the treatment of, lump touching less than, spirit obviously improves, liver function recovery is normal, follows up a case by regular visits to a year and a half patient without recurrence.
embodiment 4
The Chinese medicine preparation of lymphoid tuberculosis calming liver and clearing heat, is prepared from by following bulk drugs: Fructus Gleditsia veneer 10g, Bulbus Fritillariae Ussuriensis 12g, Radix Platycodonis 7g, Radix Salviae Miltiorrhizae 18g, Radix Scutellariae 9g, Rhizoma Cyperi 11g, Herba Erigerontis Annui 8g, Radix Polygoni Multiflori 13g, DABAIJIE potato 11g, Spica Prunellae 22g, Fructus Forsythiae 10g, Sal Ammoniacus 1.3g, Radix Ranunculi Ternati 14g.The preparation method of the Chinese medicine thick paste agent for the treatment of lymphoid tuberculosis calming liver and clearing heat:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, the micro-stir-fry of slow fire 8 minutes, takes out and puts into mortar, carefully pulverizes;
3. above-mentioned gained fine powder is put into bag filter, add the water of 7 times of medical material weight, intense fire is fried open, and slow fire boiling 50 minutes, removes medicinal residues, and residue medicinal liquid continues boiling, to medicine liquid volume simmer down to original 1/5;
4. by step 3. gained concentrated solution mix in the ratio of 1:1 with Mel, stir and obtain thick paste agent.
Using method: get two soup ladles and be as the criterion (about 30-40 milliliter), boiled water is taken after melting, and every day three times, 7 days is a course for the treatment of.
Model case: xxx, the age: 31 years old; Sex: female; Main suit a: enclosed mass appears in cervical region, pain while pressing; Existing symptom: Diagnosis of Cervical Masses is 3*1 centimetre, with calcification, growth, has tenderness sense, and leucocyte content is low; Diagnosis: through mass puncture pathological examination, be diagnosed as the tuberculosis of cervical lymph nodes.
Take the agent of this example gained thick paste, each two soup ladles, boiled water is taken after melting, and one day three times seven days is a course for the treatment of.Take after 21 days, enclosed mass obviously reduces, and softening gradually, continues to use a course for the treatment of, and patient's symptom is clearly better, and the mental status improves, self-induction recovery from illness.
embodiment 5
The Chinese medicine preparation of lymphoid tuberculosis calming liver and clearing heat, is prepared from by following bulk drugs: Fructus Gleditsia veneer 8.5g, Bulbus Fritillariae Ussuriensis 10.5g, Radix Platycodonis 6g, Radix Salviae Miltiorrhizae 15g, Radix Scutellariae 8g, Rhizoma Cyperi 10g, Herba Erigerontis Annui 7.5g, Radix Polygoni Multiflori 10.5g, DABAIJIE potato 10g, Spica Prunellae 20g, Fructus Forsythiae 9g, Sal Ammoniacus 1g, Radix Ranunculi Ternati 12g.The preparation method of the Chinese medicine decoction for the treatment of lymphoid tuberculosis calming liver and clearing heat:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 50 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, add water and do not have medical material 2-4cm to soak 25 minutes, intense fire is fried open and turns slow fire boiling 35 minutes, and filtered while hot obtains medicinal liquid;
4. recrement adds water continuation decoction, and after boiling, the persistent period is 25 minutes, obtains medicinal liquid after filtration;
5. by step 1. 2. in gained medicated powder, cross 110 mesh sieves, with step 3. 4. gained medicinal liquid mix homogeneously, sterile packaged obtains Chinese medicine decoction.
The instructions of taking of decoction of the present invention: take twice (warm) each 150-200m1,7 days courses for the treatment of every day.
test example 1the clinical practice of the Chinese medicine decoction of embodiment 5 gained treatment lymphoid tuberculosis calming liver and clearing heats:
Choose crowd: according to case that hospital is stayed, choose and be diagnosed as scrofulous patient's 256 examples,, in the range of age 15-65 year, male 126, and women 130, experimental group 156 people, matched group 100 people;
Test method: patient's random assortment is two groups, experimental group is taken the 5 gained Chinese medicine decoction treatments of this example, practical other conventional method treatments (isoniazid, rifampicin, ethambutol or excision) of matched group;
Selection standard: patient suffers from lymphoid tuberculosis and reaches more than 1 year, and lump merges mutually, and what push away is motionless, by being pressed with pain, there is diabrosis, suppuration in part lump even, and with liver dysfunction, the symptom such as weak.
Diagnostic criteria: 1. recovery from illness: lump dissipates, ulcer healing, general malaise transference cure, liver function recovery is normal; 2. effective: abscess is obviously dwindled, ulcer heals substantially, and malaise symptoms is most of to disappear, and liver function is recovered to some extent; 3. invalid: lump does not disappear, ulcer disunion, malaise symptoms does not improve.
Therapeutic effect: total effective rate=cure rate+obvious effective rate.
Table 1 is taken the lymphoid tuberculosis patient treatment result of embodiment five decoctions
Experimental group: cure rate 82.1%, obvious effective rate 16.0%, inefficiency 1.9%, total effective rate 98.1%; Matched group: cure rate 76%, obvious effective rate 14%, inefficiency 10%, total effective rate 90%.
Chinese medicine preparation of the present invention is treated scrofulous medicine with other and is compared safely, painful few, and effect is remarkable.In side, select Spica Prunellae, Radix Salviae Miltiorrhizae, Radix Ranunculi Ternati, utilize the effect of its blood circulation promoting and blood stasis dispelling, mass dissipating and swelling eliminating, heat-clearing and toxic substances removing, lymph tuberculosis is had to obvious healing effect.Through clinical trial certificate, take Chinese medicine preparation of the present invention, the scrofulous recurrence probability of patient reduces greatly, symptom before and after treatment is improved remarkable compared with conventional medicine also effect, can short-term and the healing lymphoid tuberculosis patient of safety, and can recover patient's liver function, clinical trial certificate total effective rate can reach 98.1%.
It should be pointed out that the specific embodiment is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, within the spirit and principles in the present invention all, any modification of doing, replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. lymphoid tuberculosis calming liver and clearing heat preparation, is characterized in that, the main raw material(s) that takes off row weight proportion is prepared from: Fructus Gleditsia veneer 5-12 part; Bulbus Fritillariae Ussuriensis 6-15 part; Radix Platycodonis 3-9 part; Radix Salviae Miltiorrhizae 10-20 part; Radix Scutellariae 6-10 part; Rhizoma Cyperi 8-12 part; Herba Erigerontis Annui 6-9 part; Radix Polygoni Multiflori 6-15 part; DABAIJIE potato 8-12 part; Spica Prunellae 15-25 part; Fructus Forsythiae 6-12 part; Sal Ammoniacus 0.5-1.5 part; Radix Ranunculi Ternati 8-16 part.
2. Chinese medicine preparation as claimed in claim 1, is characterized in that, the main raw material(s) that takes off row weight proportion is prepared from: Fructus Gleditsia veneer 7-10 part; Bulbus Fritillariae Ussuriensis 9-12 part; Radix Platycodonis 5-7 part; Radix Salviae Miltiorrhizae 12-18 part; Radix Scutellariae 7-9 part; Rhizoma Cyperi 9-11 part; Herba Erigerontis Annui 7-8 part; Radix Polygoni Multiflori 8-13 part; DABAIJIE potato 9-11 part; Spica Prunellae 18-22 part; Fructus Forsythiae 8-10 part; Sal Ammoniacus 0.7-1.3 part; Radix Ranunculi Ternati 10-14 part.
3. Chinese medicine preparation as claimed in claim 1, is characterized in that, the main raw material(s) that takes off row weight proportion is prepared from: 8.5 parts of Fructus Gleditsia veneer; 10.5 parts of Bulbus Fritillariae Ussuriensiss; 6 parts of Radix Platycodoniss; 15 parts of Radix Salviae Miltiorrhizaes; 8 parts of Radix Scutellariaes; 10 parts of Rhizoma Cyperis; 7.5 parts of Herba Erigerontis Annuis; 10.5 parts of Radix Polygoni Multiflori; 10 parts of DABAIJIE potatos; 20 parts of Spica Prunellaes; 9 parts of Fructus Forsythiaes; 1 part of Sal Ammoniacus; 12 parts of Radix Ranunculi Ternatis.
4. the Chinese medicine preparation as described in as arbitrary in claim 1-3, is characterized in that, this Chinese medicine preparation is made to pharmaceutically acceptable decoction, powder, pill and thick paste agent.
5. the preparation method of arbitrary described Chinese medicine preparation in claim 4, is characterized in that, the preparation process of described decoction is as follows:
1. get Sal Ammoniacus, thermokalite water soaking 40-60 minute (preferably 50 minutes) with 2%, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, adding water did not have medical material 2-4cm to soak 20-30 minute (preferably 25 minutes), intense fire is fried open and turns slow fire boiling 30-40 minute (preferably 35 minutes), and filtered while hot obtains medicinal liquid;
4. recrement adds water continuation decoction, and after boiling, the persistent period is 20-30 minute (preferably 25 minutes), obtains medicinal liquid after filtration;
5. by step 1. 2. in gained medicated powder, cross 100-120 mesh sieve (preferably 110 orders), with step 3. 4. gained medicinal liquid mix homogeneously, sterile packaged obtains Chinese medicine decoction.
6. Chinese medicine preparation as claimed in claim 5, is characterized in that, it is 4 times of medical material weight that described step adds clear water amount in 4..
7. Chinese medicine preparation as claimed in claim 4, is characterized in that, the preparation process of described powder is as follows:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, the micro-stir-fry of slow fire 5-10 minute (preferably 7 minutes), takes out and puts into mortar, carefully pulverizes;
4. above-mentioned gained fine powder is mixed, cross 100-120 mesh sieve (preferably 110 orders), according to the specification of 5g/ bag, make powder.
8. Chinese medicine preparation as claimed in claim 4, is characterized in that, the preparation process of described pill is as follows:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato are cleaned to stripping and slicing, with edible oil, explode and to surface, be yellow, after taking-up, grind to form fine powder;
3. Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, the micro-stir-fry of slow fire 5-10 minute (preferably 7 minutes), takes out and puts into mortar, carefully pulverizes;
4. above-mentioned gained fine powder is crossed to 110 mesh sieves and starch mixes, ratio is 2:1, adds the general ball of making of water, obtains pill.
9. Chinese medicine preparation as claimed in claim 4, is characterized in that, the preparation method of described thick paste agent:
1. get Sal Ammoniacus, the thermokalite water soaking with 2% 40 minutes, then use the clean alkali liquor of clear water rinsing, after being dried, pulverize;
2. Fructus Gleditsia veneer, Bulbus Fritillariae Ussuriensis, DABAIJIE potato, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are put into marmite, the micro-stir-fry of slow fire 8 minutes, takes out and puts into mortar, carefully pulverizes;
3. above-mentioned gained fine powder is put into bag filter, add the water of 7 times of medical material weight, intense fire is fried open, and slow fire boiling 50 minutes, removes medicinal residues, and residue medicinal liquid continues boiling, to medicine liquid volume simmer down to original 1/5;
4. by step 3. gained concentrated solution mix in the ratio of 1:1 with Mel, stir and obtain thick paste agent.
10. the application of the Chinese medicine preparation as described in as arbitrary in claim 1-3 when the scrofulous medicine of preparation treatment.
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Address after: 730000 Gansu province Xigu District of Lanzhou City Xinye Road No. 102-182 Applicant after: Wang Shumei Address before: 250014, No. 5, building seven, East District, Ming Lake District, Lixia District, Shandong, Ji'nan Applicant before: Wang Shumei |
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Application publication date: 20141210 |