CN104172418A - 一种治疗泌尿性结石的醋饮及其制备方法 - Google Patents
一种治疗泌尿性结石的醋饮及其制备方法 Download PDFInfo
- Publication number
- CN104172418A CN104172418A CN201410435783.6A CN201410435783A CN104172418A CN 104172418 A CN104172418 A CN 104172418A CN 201410435783 A CN201410435783 A CN 201410435783A CN 104172418 A CN104172418 A CN 104172418A
- Authority
- CN
- China
- Prior art keywords
- parts
- vinegar
- preparation
- calculus
- drink
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000021419 vinegar Nutrition 0.000 title claims abstract description 81
- 239000000052 vinegar Substances 0.000 title claims abstract description 81
- 238000002360 preparation method Methods 0.000 title claims description 39
- 206010007027 Calculus urinary Diseases 0.000 title abstract description 9
- 208000009911 Urinary Calculi Diseases 0.000 title abstract 5
- 235000013361 beverage Nutrition 0.000 title abstract 4
- 240000008042 Zea mays Species 0.000 claims abstract description 40
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 40
- 239000004575 stone Substances 0.000 claims abstract description 37
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 35
- 235000005822 corn Nutrition 0.000 claims abstract description 35
- 210000000582 semen Anatomy 0.000 claims abstract description 26
- 235000008671 Calycanthus floridus Nutrition 0.000 claims abstract description 25
- 235000008670 Calycanthus occidentalis Nutrition 0.000 claims abstract description 25
- 244000148992 Lindera benzoin Species 0.000 claims abstract description 25
- 235000004520 Lindera benzoin Nutrition 0.000 claims abstract description 25
- 235000008262 Lindera benzoin var. benzoin Nutrition 0.000 claims abstract description 25
- 241000903946 Clematidis Species 0.000 claims abstract description 22
- 240000005702 Galium aparine Species 0.000 claims abstract description 22
- 235000014820 Galium aparine Nutrition 0.000 claims abstract description 21
- 241001598107 Imperata Species 0.000 claims abstract description 21
- 241000112528 Ligusticum striatum Species 0.000 claims abstract description 21
- 239000002994 raw material Substances 0.000 claims abstract description 16
- 238000011282 treatment Methods 0.000 claims description 38
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 26
- 235000003283 Pachira macrocarpa Nutrition 0.000 claims description 23
- 235000014364 Trapa natans Nutrition 0.000 claims description 23
- 235000009165 saligot Nutrition 0.000 claims description 23
- 239000000706 filtrate Substances 0.000 claims description 21
- 238000009835 boiling Methods 0.000 claims description 18
- 241001083492 Trapa Species 0.000 claims description 15
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 14
- 239000006228 supernatant Substances 0.000 claims description 14
- 238000012376 hot air sterilization Methods 0.000 claims description 13
- 238000007789 sealing Methods 0.000 claims description 11
- 241000219198 Brassica Species 0.000 claims description 8
- 235000011331 Brassica Nutrition 0.000 claims description 8
- 240000001085 Trapa natans Species 0.000 claims description 8
- 238000001802 infusion Methods 0.000 claims description 8
- 208000003643 Callosities Diseases 0.000 claims description 7
- 206010020649 Hyperkeratosis Diseases 0.000 claims description 7
- 235000008216 herbs Nutrition 0.000 claims description 7
- 229910052742 iron Inorganic materials 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 7
- FFBHFFJDDLITSX-UHFFFAOYSA-N benzyl N-[2-hydroxy-4-(3-oxomorpholin-4-yl)phenyl]carbamate Chemical compound OC1=C(NC(=O)OCC2=CC=CC=C2)C=CC(=C1)N1CCOCC1=O FFBHFFJDDLITSX-UHFFFAOYSA-N 0.000 claims description 2
- 208000002193 Pain Diseases 0.000 abstract description 26
- 239000003814 drug Substances 0.000 abstract description 24
- 230000000694 effects Effects 0.000 abstract description 17
- 210000002700 urine Anatomy 0.000 abstract description 12
- 229940079593 drug Drugs 0.000 abstract description 5
- 241001596950 Larimichthys crocea Species 0.000 abstract description 3
- 230000001939 inductive effect Effects 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 244000025254 Cannabis sativa Species 0.000 abstract 1
- 244000285774 Cyperus esculentus Species 0.000 abstract 1
- 235000005853 Cyperus esculentus Nutrition 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 10
- 208000026435 phlegm Diseases 0.000 description 10
- 208000004880 Polyuria Diseases 0.000 description 9
- 230000035619 diuresis Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- 208000024891 symptom Diseases 0.000 description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 230000002485 urinary effect Effects 0.000 description 8
- 201000010099 disease Diseases 0.000 description 7
- 210000003734 kidney Anatomy 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 210000001015 abdomen Anatomy 0.000 description 6
- 230000035622 drinking Effects 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 6
- 241000345998 Calamus manan Species 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 5
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 5
- 239000000796 flavoring agent Substances 0.000 description 5
- 235000019634 flavors Nutrition 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 235000009973 maize Nutrition 0.000 description 5
- 230000027939 micturition Effects 0.000 description 5
- 235000012950 rattan cane Nutrition 0.000 description 5
- 230000008961 swelling Effects 0.000 description 5
- 210000003932 urinary bladder Anatomy 0.000 description 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- 240000007594 Oryza sativa Species 0.000 description 4
- 235000007164 Oryza sativa Nutrition 0.000 description 4
- 206010037660 Pyrexia Diseases 0.000 description 4
- 210000000038 chest Anatomy 0.000 description 4
- 208000015181 infectious disease Diseases 0.000 description 4
- 235000009566 rice Nutrition 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 206010030113 Oedema Diseases 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- 235000012907 honey Nutrition 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 206010025482 malaise Diseases 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000008506 pathogenesis Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 208000006820 Arthralgia Diseases 0.000 description 2
- 206010007026 Calculus urethral Diseases 0.000 description 2
- 241000218158 Clematis Species 0.000 description 2
- 241000786785 Clematis montana Species 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000287828 Gallus gallus Species 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- 201000009906 Meningitis Diseases 0.000 description 2
- 208000012287 Prolapse Diseases 0.000 description 2
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 2
- 229930003268 Vitamin C Natural products 0.000 description 2
- 208000000260 Warts Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 206010013990 dysuria Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 210000004317 gizzard Anatomy 0.000 description 2
- 229930182470 glycoside Natural products 0.000 description 2
- 150000002338 glycosides Chemical class 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 208000006750 hematuria Diseases 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 2
- 210000004379 membrane Anatomy 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 231100000862 numbness Toxicity 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 229930182490 saponin Natural products 0.000 description 2
- 201000010153 skin papilloma Diseases 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- -1 trisaccharide saponin Chemical class 0.000 description 2
- 210000000626 ureter Anatomy 0.000 description 2
- 201000009160 urethral calculus Diseases 0.000 description 2
- 208000008281 urolithiasis Diseases 0.000 description 2
- 235000019154 vitamin C Nutrition 0.000 description 2
- 239000011718 vitamin C Substances 0.000 description 2
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 1
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 description 1
- OWODMVTTWPVWQA-COFJZONBSA-N (2s,4ar,6ar,6as,6br,8ar,9r,10r,11s,12ar,14bs)-10,11-dihydroxy-9-(hydroxymethyl)-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-2,4a-dicarboxylic acid Chemical compound C([C@H]1C2=CC[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C(O)=O)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)C[C@H](O)[C@H](O)[C@]1(CO)C OWODMVTTWPVWQA-COFJZONBSA-N 0.000 description 1
- NTWLPZMPTFQYQI-UHFFFAOYSA-N (3alpha)-olean-12-ene-3,23-diol Natural products C1CC(O)C(C)(CO)C2CCC3(C)C4(C)CCC5(C)CCC(C)(C)CC5C4=CCC3C21C NTWLPZMPTFQYQI-UHFFFAOYSA-N 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 240000006995 Abutilon theophrasti Species 0.000 description 1
- 240000008027 Akebia quinata Species 0.000 description 1
- 235000007756 Akebia quinata Nutrition 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 229910001369 Brass Inorganic materials 0.000 description 1
- 241000219193 Brassicaceae Species 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 241000282994 Cervidae Species 0.000 description 1
- 241001672694 Citrus reticulata Species 0.000 description 1
- 241000601164 Clematis orientalis Species 0.000 description 1
- 244000205754 Colocasia esculenta Species 0.000 description 1
- 235000006481 Colocasia esculenta Nutrition 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 208000012895 Gastric disease Diseases 0.000 description 1
- 206010018045 Gastroptosis Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- GCGBHJLBFAPRDB-UHFFFAOYSA-N Hederagenin Natural products CC1(C)CCC2(CCC3(C)C4CCC5C(C)(CO)C(O)CCC5(C)C4CC=C3C2C1)C(=O)O GCGBHJLBFAPRDB-UHFFFAOYSA-N 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000006083 Hypokinesia Diseases 0.000 description 1
- OWODMVTTWPVWQA-UHFFFAOYSA-N Jaligonic acid Natural products C12CC=C3C4CC(C)(C(O)=O)CCC4(C(O)=O)CCC3(C)C1(C)CCC1C2(C)CC(O)C(O)C1(CO)C OWODMVTTWPVWQA-UHFFFAOYSA-N 0.000 description 1
- 240000007049 Juglans regia Species 0.000 description 1
- 235000009496 Juglans regia Nutrition 0.000 description 1
- 208000000913 Kidney Calculi Diseases 0.000 description 1
- 241000356842 Larimichthys polyactis Species 0.000 description 1
- 244000241838 Lycium barbarum Species 0.000 description 1
- 235000015459 Lycium barbarum Nutrition 0.000 description 1
- 208000037093 Menstruation Disturbances Diseases 0.000 description 1
- 206010027339 Menstruation irregular Diseases 0.000 description 1
- 240000003433 Miscanthus floridulus Species 0.000 description 1
- 241001529936 Murinae Species 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- 206010028817 Nausea and vomiting symptoms Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 241000356847 Otolithes Species 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 241000209504 Poaceae Species 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 241000545442 Radix Species 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 206010038419 Renal colic Diseases 0.000 description 1
- 206010062237 Renal impairment Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 240000004980 Rheum officinale Species 0.000 description 1
- 235000008081 Rheum officinale Nutrition 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 208000006268 Sarcoma 180 Diseases 0.000 description 1
- GCGBHJLBFAPRDB-KCVAUKQGSA-N Scutellaric acid Natural products CC1(C)CC[C@@]2(CC[C@@]3(C)[C@@H]4CC[C@H]5[C@@](C)(CO)[C@H](O)CC[C@]5(C)[C@H]4CC=C3[C@@H]2C1)C(=O)O GCGBHJLBFAPRDB-KCVAUKQGSA-N 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 208000000014 Ureteral Calculi Diseases 0.000 description 1
- 208000006568 Urinary Bladder Calculi Diseases 0.000 description 1
- 206010046555 Urinary retention Diseases 0.000 description 1
- 206010046788 Uterine haemorrhage Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- MXZRMHIULZDAKC-UHFFFAOYSA-L ammonium magnesium phosphate Chemical compound [NH4+].[Mg+2].[O-]P([O-])([O-])=O MXZRMHIULZDAKC-UHFFFAOYSA-L 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000001663 anti-spastic effect Effects 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 201000007201 aphasia Diseases 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- COUXBBBIXWWAEP-AGUBZPQCSA-N asperuloside Natural products CC(=O)OCC1=C[C@@H]2OC(=O)C3=CO[C@@H](OC[C@H]4O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]4O)[C@H]1[C@H]23 COUXBBBIXWWAEP-AGUBZPQCSA-N 0.000 description 1
- IBIPGYWNOBGEMH-DILZHRMZSA-N asperuloside Chemical compound O([C@@H]1OC=C2C(=O)O[C@H]3C=C([C@@H]1[C@H]32)COC(=O)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O IBIPGYWNOBGEMH-DILZHRMZSA-N 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 208000002894 beriberi Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 229940116229 borneol Drugs 0.000 description 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 description 1
- 239000010951 brass Substances 0.000 description 1
- QXDMQSPYEZFLGF-UHFFFAOYSA-L calcium oxalate Chemical compound [Ca+2].[O-]C(=O)C([O-])=O QXDMQSPYEZFLGF-UHFFFAOYSA-L 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 230000002279 cholagogic effect Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000002574 cystoscopy Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 206010016766 flatulence Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 208000027692 gas pain Diseases 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- PGOYMURMZNDHNS-MYPRUECHSA-N hederagenin Chemical compound C1C[C@H](O)[C@@](C)(CO)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C PGOYMURMZNDHNS-MYPRUECHSA-N 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 235000021268 hot food Nutrition 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 229940087305 limonene Drugs 0.000 description 1
- 235000001510 limonene Nutrition 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 description 1
- 208000010553 multiple abscesses Diseases 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 230000002842 otolith Effects 0.000 description 1
- 210000001265 otolithic membrane Anatomy 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 210000003516 pericardium Anatomy 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 231100000857 poor renal function Toxicity 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 235000020234 walnut Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗泌尿性结石的醋饮，取下述重量配比的主要原料制备而成：白芥子9-15份，玉米6-12份，甘草10-15份，枳壳5-10份，乌药6-12份，白茅根15-60份，川芎5-15份，鱼脑石4.5-9份，荸荠5-15份，川木通2-5份，八仙草5-15份，醋60-100份。本发明具有利尿通淋、利水渗湿之功效，对由泌尿性结石引起的疼痛、尿赤、排尿困难有很好的治疗作用，能够极有效且较为快速的治疗泌尿性结石，是一种治疗泌尿性结石较为理想安全的药物。
Description
技术领域
本发明属中医中药领域，尤其是涉及一种治疗泌尿性结石的醋饮及其制备方法。
背景技术
泌尿性结石又称***、尿石症，是泌尿系的常见病。是指在泌尿***内因尿液浓缩沉淀形成颗粒或成块样聚集物，为泌尿***常见病，好发于青壮年，近年来随着环境污染的不断扩大，人们生活习惯的改变，泌尿系结石的病人在不断地增加。泌尿性结石是肾、输尿管、膀胱、尿道结石的总称，结石可见于肾、膀胱、输尿管和尿道的任何部位。按***所在的部位基本分为上***和下***。上***是指肾和输尿管结石；下***包括膀胱结石和尿道结石。当尿中形成结石晶体的盐类呈饱和状态、抑制晶体形成物质不足和核基质的存在就会形成结石，结石成分有草酸钙、磷酸钙和磷酸镁铵等。泌尿性结石的致病原因较为为复杂，中医认为泌尿系结石的病因病机为《诸病源候论》载：“诸淋者，由肾虚而膀胱热故也”的影响，认为其病因病机主要是肾虚膀胱气化无力失司，湿热蕴结，煎熬津液．日久月累，聚而成石。泌尿性结石以突然发生的剧烈腰痛、牵引少腹，尿频、尿急、尿痛、尿色混浊，甚至尿中有血或砂石为主要临床表现。泌尿系结石可引起尿路损伤、梗阻，并发感染，致使肾功能受损，所以一旦检查发现患泌尿性结石应及时治疗。对于泌尿性结石，西医的治疗方法是小结石(直径在0.5厘米以下)采用多饮水，依靠身体自身机能等待排石，此方法使患者十分被动，在等待排石的过程中，患者依然要忍受病痛的折磨；大结石采用手术治疗，即通过内腔镜(如肾盂镜、输尿管镜)下取石术、体外震波碎石术及膀胱结石的***疗法等，效果虽好，但手术费用较高，且碎石排出过程中，可能引起肾绞痛，给患者造成额外的身体负担。
在已有中医中药领域治疗泌尿性结石的技术中，授权公告号 CN 102125605 B（申请号 201010019338.3）的专利文件公开了一种具有治疗泌尿系结石，同时又有补肾作用的中药颗粒制剂，其特征在于该中药制剂的组分以及重量分数为：枸杞30 份、冬葵子15 份、滑石30 份、木通12 份、鹿角胶15 份、鸡内金12 份、鸡内金12 份、白芥子15 份、甘草6 份、黄芪30 份、大黄15 份，同时，在本配方中加入蜂蜜2-8 份。中国发明专利申请CN02153898.0于2003年5月28日公开了一种名称为“一种治疗泌尿系结石的中药制剂及其制备方法”，它是以中药胡桃仁为原料，经压榨出油、醇提醇沉、喷雾干燥等工艺得到胡桃仁油和胡桃仁提取物干粉，两者再按一定比例量混合均匀，以混合物的药物活性成分制成适合服用的剂型，此发明配方简单，只有核桃仁一味原料，无法做到对不同部位的泌尿性结石进行辨证治疗的目的，且加工提炼工序麻烦，成本较高。
发明内容
针对现有的治疗现状，本发明的目的之一在于提供一种治疗泌尿性结石的醋饮，具有易操作、疗效显著、病患承受痛苦小的特点，并且它采用地方上较为常见的中药材作为原料，成本低廉。
本发明的另一目的就是提供上述治疗泌尿性结石醋饮的制备方法。
本发明的上述目的是通过以下技术方案来实现的：
一种治疗泌尿性结石的醋饮，取下述重量配比的主要原料制备而成：白芥子9-15份，玉米6-12份，甘草10-15份，枳壳5-10份，乌药6-12份，白茅根15-60份，川芎5-15份，鱼脑石4.5-9份，荸荠5-15份，川木通2-5份，八仙草5-15份，醋60-100份。
上述治疗泌尿性结石的醋饮，取下述重量配比的主要原料制备而成：白芥子10-12份，玉米7-10份，甘草11-14份，枳壳6-9份，乌药9-11份，白茅根25-40份，川芎8-11份，鱼脑石5-8份，荸荠7-12份，川木通3-4份，八仙草7-12份，醋70-90份。
上述治疗泌尿性结石的醋饮，取下述重量配比的主要原料制备而成：白芥子10份，玉米8份，甘草12份，枳壳8份，乌药10份，白茅根30份，川芎10份，鱼脑石6.5份，荸荠10份，川木通3.5份，八仙草10份，醋80份。
一种治疗泌尿性结石的醋饮的制备方法，具体有以下步骤制备而成：
①取新鲜的玉米，切成块，置于砂锅内，加水微火慢煮1-3小时，过滤，滤液备用；
②将鱼脑石置于小火上，烧至外部焦黑为度，使药物表面部分炭化，然后研磨成细末，过80-120目筛；
③将醋加入到步骤①所得滤液中，一边用大铁勺搅拌一边熬煮，待滤液煮开后加入白芥子，甘草，枳壳，乌药，白茅根，川芎、荸荠、川木通、八仙草和步骤②所得鱼脑石，武火煎开，转文火煎煮20-40分钟，密封静置10-15小时，取上清液待用；
④将步骤③所得上清液，于80-100℃干热灭菌，密封于塑料瓶中，即得醋饮。
上述醋饮的制备方法，制备步骤①水的用量是玉米重量的8-12倍（优选的，水的用量是玉米重量的9-11倍，更佳优选的，水的用量是玉米重量的10倍）。
上述醋饮的制备方法，制备步骤①加水微火慢煮1.5-2.5小时（优选的加水微火慢煮2小时）。
上述醋饮的制备方法，制备步骤②细末过90-110目筛（优选过100目筛）。
上述醋饮的制备方法，制备步骤③武火煎开，转文火煎煮25-35分钟（优选武火煎开，转文火煎煮30分钟）。
上述醋饮的制备方法，制备步骤③密封静置11-14小时（优选的密封静置12小时）。
上述醋饮的制备方法，制备步骤④于80-100℃干热灭菌3-9分钟（优选的，于85-95℃干热灭菌5-7分钟，更佳优选的，于90℃干热灭菌6分钟）。
上述醋饮的制备方法，优选的，以米醋为最佳的制备醋饮原料。
使用方法：一日3-6次，每次取本发明醋饮40-50ml，可根据个人口味添加糖或者蜂蜜，10天为一个疗程。
该醋饮对泌尿性结石效果显著，有止痛、利尿的功效。方中的玉米经过加工后变成玉米水，玉米水有甘甜的味道，加入米醋和中药熬煮后得到酸甜口味的醋饮，方中白芥子、甘草和川芎均有止痛的功效，能在服药初期快速缓解患者的疼痛症状，使患者有坚持治疗的信心；枳壳、白茅根、鱼脑石、荸荠、川木通和八仙草均有利尿的作用，可以促使结石顺畅快速的排出，减轻患者的身体痛苦与负担。
各原料药的药理功效分别为：
白芥子：白芥子，别名辣菜子，拉丁文名一年或二年生植物白芥的干燥成熟种子。十字花科，呈球形，表面灰白色至淡黄色，种皮薄而脆，有油性。无臭，味辛辣。可入药。温肺豁痰利气，散结通络止痛，化痰逐饮；散结消肿。主咳喘痰多；胸满胁痛；肢体麻木；关节肿痛；湿痰流注；阴疽肿毒。治乳痈、乳癌、乳腺疼痛、结核、痰饮咳喘，胸胁胀满疼痛，反胃呕吐，中风不语，肢体痹痛麻木，脚气，阴疽，肿毒，跌打肿痛。
玉米：玉米亦称玉蜀黍、包谷、苞米、棒子；粤语称为粟米，闽南语称作番麦，是一年生禾本科草本植物，具有利尿、降压、利胆、降血糖的功效。
甘草：性味: 甘，平。归经: 归心。肺、脾、胃经。功效: 补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。主治: 用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，院腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
枳壳：性味: 苦、辛、酸，温。归经: 归脾、胃经。功效: 理气宽中，行滞消胀。主治: 用于胸胁气滞．胀满疼痛，食积不化，痰饮内停；胃下垂，脱肛，子宫脱垂。乌药：味甘，性平。有利水渗湿的功效，主要用于小便不利。
乌药：1 挥发油的兴奋作用：内服时，有兴奋大脑皮质的作用，并有促进呼吸，兴奋心肌，加速血循环，升高血压及发汗的作用。局部外用使局部血管扩张，血循环加速，缓和肌肉痉挛性疼痛。2、抑菌作用：对金黄色葡萄球菌，甲型溶血性链球菌，伤寒杆菌，变形杆菌，绿脓杆菌，大肠杆菌均有抑制作用。3、对消化道的影响：有报导乌药对胃肠平滑肌有双重作用，此外，乌药能增加消化液的分泌。4、止血作用：体外实验证明，乌药干粉能明显缩短家兔血浆再钙化时间，促进血凝及良好的止血作用。5、其它作用：用乌药长期喂大鼠，可使体重增加，并对小鼠肉瘤-180有抑制作用。其龙脑可发汗、兴奋、镇痉、驱虫等
白茅根：性味: 甘，寒。归经: 归肺、胃、膀胱经。功效: 凉血止血，清热利尿。主治: 用于血热吐血．衄血，尿血，热病烦渴，黄疸，水肿，热淋涩痛；急性肾炎水肿。
川芎：性味: 辛，温。归经: 归肝、胆、心包经。功效: 活血行气，祛风止痛。 主治: 用于***．经闭痛经，癥瘕腹痛，胸胁刺痛，跌扑肿痛，头痛。风湿痹痛。
鱼脑石：基原：为石首鱼科黄鱼属动物大黄鱼和小黄鱼的头骨中的耳石。药性：甘、咸，平。功用主治：化石，通淋，解毒。主治石淋，小便淋沥不畅，鼻渊，聤耳出脓。
荸荠：荸荠:别名马蹄、乌芋、地栗。性味功效:甘、寒。功能清热、化痰、消积、化疣。适用于温病消渴、黄疸、热淋、痞积、目赤、咽喉肿痛、赘疣等。预防急性传染病、清热泻火、凉血解毒、利尿通便祛痰、消食除胀，调理痔疮或痢疾便血、妇女崩漏、阴虚肺燥、痰热咳嗽、咽喉不利、痞块积聚、目赤障翳、辅助退烧等功效。此外，荸荠含有一种抗病毒物质可抑制流脑，流感病毒，能用于预防流脑及流感的传播。
川木通：川木通：基原：为毛莨科铁线莲属植物小木通、绣球藤等的藤茎。成分：1.小木通 含黄铜苷类成分：威灵仙苷。2.绣球藤 含有以常春藤皂苷元为苷元的六糖皂苷及三糖皂苷。药性：淡、微苦，寒。功用主治：清热利尿，通经下乳。主治湿热癃闭，水肿，淋证，口舌生疮，湿热痹痛，关节不利，妇人闭经，乳汁不通。宜忌：气弱津伤，精滑遗尿，小便过多及孕妇慎服。
八仙草：又名锯子草、拉拉藤、飞扬藤，味茜草科拉拉藤属植物猪殃殃或粗叶拉拉藤的全草。药性：全草纤细，易破碎，表面灰绿或绿褐色，气微，味辛、味苦，性微寒。成分：猪殃殃地上部分含生物碱，果实含大麦芽胺，加利果酸等；粗叶拉拉藤地上部分含车叶草苷，维生素C。根据现代药理研究发现，该药具有抑菌、抗癌、清热解毒、利尿通淋、消肿止痛的功效，用于痈疽肿毒，阑尾炎，感冒发热，尿血等。
米醋：米醋是众多种类醋中营养价值较高的一种，含有丰富的碱性氨基酸、糖类物质、有机酸、维生素B1、维生素B2、维生素C、无机盐、矿物质等，具有祛脂降压,降低胆固醇,解毒,解酒,消食,减肥,安神除烦,有益心血管。
本发明醋饮基于中医中药辩症治疗的原理。选用的药材有用于表症止痛、利尿的，也有用于里症除热调肾的，属于内外兼顾且安全有效的药物，对泌尿性结石有极好的治疗作用。
具体实施方式
下面结合实施例和实验例详细说明本发明的技术方案，但保护范围不被此限制。
实施例 1一种治疗泌尿性结石的醋饮，取下述重量配比的主要原料制备而成（每份取10g）：白芥子9份，玉米6份，甘草10份，枳壳5份，乌药6份，白茅根15份，川芎5份，鱼脑石4.5份，荸荠5份，川木通2份，八仙草5份，醋60份。
上述治疗泌尿性结石的醋饮的制备方法，步骤如下：
①取新鲜的玉米，切成块，置于砂锅内，加水微火慢煮1小时，水的用量是玉米重量的8倍，过滤，滤液备用；
②将鱼脑石置于小火上，烧至外部焦黑为度，使药物表面部分炭化，然后研磨成细末，过80目筛；
③将醋加入到步骤①所得滤液中，一边用大铁勺搅拌一边熬煮，待滤液煮开后加入白芥子，甘草，枳壳，乌药，白茅根，川芎、荸荠、川木通、八仙草和步骤②所得鱼脑石，武火煎开，转文火煎煮20分钟，密封静置10小时，取上清液待用；
④将步骤③所得上清液，于80℃干热灭菌3分钟，密封于塑料瓶中，即得醋饮。
典型病例一朱XX，男，52岁，山东省德州人士，某高校的教师，不明原因的右侧腰痛，发作时大汗淋漓，疼痛向同侧腹股沟放射，半个月前曾出现尿频、尿痛的症状，仔细观察发现有血尿症状，医院诊断为肾窦近中部有0.3*0.4cm强回声光斑，确诊为泌尿性结石，由于患者想继续给学生上课，又坚持保守治疗，医生就建议饮用本发明醋饮。
饮用实施例1所得的醋饮，饮用1天，小便顺畅了很多，疼痛有所减轻，继续饮用4天，疼痛基本消失，小便顺畅，继续服用10周，去医院检查，结石已完全排出，停药至今未复发。
实施例 2一种治疗泌尿性结石的醋饮，取下述重量配比的主要原料制备而成（每份取10g）：白芥子15份，玉米12份，甘草15份，枳壳10份，乌药12份，白茅根60份，川芎15份，鱼脑石9份，荸荠15份，川木通5份，八仙草15份，醋100份。
上述治疗泌尿性结石的醋饮的制备方法，步骤如下：
①取新鲜的玉米，切成块，置于砂锅内，加水微火慢煮3小时，水的用量是玉米重量的12倍，过滤，滤液备用；
②将鱼脑石置于小火上，烧至外部焦黑为度，使药物表面部分炭化，然后研磨成细末，过120目筛；
③将醋加入到步骤①所得滤液中，一边用大铁勺搅拌一边熬煮，待滤液煮开后加入白芥子，甘草，枳壳，乌药，白茅根，川芎、荸荠、川木通、八仙草和步骤②所得鱼脑石，武火煎开，转文火煎煮40分钟，密封静置15小时，取上清液待用；
④将步骤③所得上清液，于80-100℃干热灭菌9分钟，密封于塑料瓶中，即得醋饮。
实施例 3一种治疗泌尿性结石的醋饮，取下述重量配比的主要原料制备而成（每份取10g）：白芥子10份，玉米7份，甘草11份，枳壳6份，乌药9份，白茅根25份，川芎8份，鱼脑石5份，荸荠7份，川木通3份，八仙草7份，醋70份。
上述治疗泌尿性结石的醋饮的制备方法，步骤如下：
①取新鲜的玉米，切成块，置于砂锅内，加水微火慢煮1.5小时，水的用量是玉米重量的9倍，过滤，滤液备用；
②将鱼脑石置于小火上，烧至外部焦黑为度，使药物表面部分炭化，然后研磨成细末，过90目筛；
③将醋加入到步骤①所得滤液中，一边用大铁勺搅拌一边熬煮，待滤液煮开后加入白芥子，甘草，枳壳，乌药，白茅根，川芎、荸荠、川木通、八仙草和步骤②所得鱼脑石，武火煎开，转文火煎煮25分钟，密封静置11小时，取上清液待用；
④将步骤③所得上清液，于85℃干热灭菌5分钟，密封于塑料瓶中，即得醋饮。
实施例 4一种治疗泌尿性结石的醋饮，取下述重量配比的主要原料制备而成（每份取10g）：白芥子12份，玉米10份，甘草14份，枳壳9份，乌药11份，白茅根40份，川芎11份，鱼脑石8份，荸荠12份，川木通4份，八仙草12份，醋90份。
上述治疗泌尿性结石的醋饮的制备方法，步骤如下：
①取新鲜的玉米，切成块，置于砂锅内，加水微火慢煮2.5小时，水的用量是玉米重量的11倍，过滤，滤液备用；
②将鱼脑石置于小火上，烧至外部焦黑为度，使药物表面部分炭化，然后研磨成细末，过110目筛；
③将醋加入到步骤①所得滤液中，一边用大铁勺搅拌一边熬煮，待滤液煮开后加入白芥子，甘草，枳壳，乌药，白茅根，川芎、荸荠、川木通、八仙草和步骤②所得鱼脑石，武火煎开，转文火煎煮35分钟，密封静置14小时，取上清液待用；
④将步骤③所得上清液，于95℃干热灭菌7分钟，密封于塑料瓶中，即得醋饮。
典型病例二：俎XX，女，60岁，山东济南人士。2年前有过泌尿性结石，在医院进行碎石治疗痊愈出院，出院后半年复发，但最近反复出现排尿困难，尿不尽，下腹胀痛，去医院经B超、X线检查，膀胱镜检查，发现有结石0.7*0.6cm，诊断为泌尿性结石，由于碎石法对俎女士不太实用，所以医生建议其饮用本发明所得醋饮。
饮用实施例4所得的醋饮，服用5天，排尿困难症状好转，疼痛减轻；饮用20天，期间有小块结石随尿液排出，小便基本正常；继续饮用1个月，去医院检查结石已完全排出；减少药量服用继续巩固10天，停药至今未复发。
实施例 5一种治疗泌尿性结石的醋饮，取下述重量配比的主要原料制备而成（每份取10g）：白芥子10份，玉米8份，甘草12份，枳壳8份，乌药10份，白茅根30份，川芎10份，鱼脑石6.5份，荸荠10份，川木通3.5份，八仙草10份，醋80份。
上述治疗泌尿性结石的醋饮的制备方法，步骤如下：
①取新鲜的玉米，切成块，置于砂锅内，加水微火慢煮2小时，水的用量是玉米重量的10倍，过滤，滤液备用；
②将鱼脑石置于小火上，烧至外部焦黑为度，使药物表面部分炭化，然后研磨成细末，过100目筛；
③将醋加入到步骤①所得滤液中，一边用大铁勺搅拌一边熬煮，待滤液煮开后加入白芥子，甘草，枳壳，乌药，白茅根，川芎、荸荠、川木通、八仙草和步骤②所得鱼脑石，武火煎开，转文火煎煮30分钟，密封静置12小时，取上清液待用；
④将步骤③所得上清液，于90℃干热灭菌6分钟，密封于塑料瓶中，即得醋饮。
试验例：实施例5所得治疗泌尿性结石的醋饮的临床应用：2008年6月-2011年12月，在4所医院筛选200例患者，其中女性100例，男性100例，年龄最大的72岁，最小年龄28岁，平均年龄50岁。试验之前1周，对该人群进行连续观察，记录症状及变化，随机分为两组，实验组及对照组，实验组服用实施例5所得产品，对照组服用其它药品（例如苧麻二金汤、化瘀排石汤等常规治疗泌尿性结石的药物）。使用方法为: 一日3-6次，每次取本发明醋饮40-50ml，可根据个人口味添加糖或者蜂蜜，10天为一个疗程，在饮用本发明的同时配合多喝水。疗效情况判定标准:治愈:饮用本品后，不适症状消失，结石完全排出；有效：饮用本品后，不适症状减轻或部分消失，结石基本排出；无效：饮用本品一个疗程，不适症状无变化。结果如表1所示。
表1:服用实施例5产品28-72岁泌尿性结石患者治疗结果
治疗效果：治愈85例（85%）， 有效10例（10%），无效5例（5%），总有效率95%。效果明显优于对照组。
经临床试验证明，对于直径0.5cm以下的结石，饮用本品5天即可有部分结石排出，严重者，饮用本品10天也会有好转，且治疗过程中无副作用，费用低廉，复发率极低，是治疗泌尿性结石安全且有效的药物。
Claims (10)
1.一种治疗泌尿性结石的醋饮，其特征在于：取下述重量配比的主要原料制备而成：白芥子9-15份，玉米6-12份，甘草10-15份，枳壳5-10份，乌药6-12份，白茅根15-60份，川芎5-15份，鱼脑石4.5-9份，荸荠5-15份，川木通2-5份，八仙草5-15份，醋60-100份。
2.根据权利要求1所述的治疗泌尿性结石的醋饮，其特征在于：取下述重量配比的主要原料制备而成：白芥子10-12份，玉米7-10份，甘草11-14份，枳壳6-9份，乌药9-11份，白茅根25-40份，川芎8-11份，鱼脑石5-8份，荸荠7-12份，川木通3-4份，八仙草7-12份，醋70-90份。
3.根据权利要求1所述的治疗泌尿性结石的醋饮，其特征在于：取下述重量配比的主要原料制备而成：白芥子10份，玉米8份，甘草12份，枳壳8份，乌药10份，白茅根30份，川芎10份，鱼脑石6.5份，荸荠10份，川木通3.5份，八仙草10份，醋80份。
4.根据权利要求1-3任一项所述的治疗泌尿性结石的醋饮的制备方法，其特征在于：步骤而成：
①取新鲜的玉米，切成块，置于砂锅内，加水微火慢煮1-3小时，过滤，滤液备用；
②将鱼脑石置于小火上，烧至外部焦黑为度，使药物表面部分炭化，然后研磨成细末，过80-120目筛；
③将醋加入到步骤①所得滤液中，一边用大铁勺搅拌一边熬煮，待滤液煮开后加入白芥子，甘草，枳壳，乌药，白茅根，川芎、荸荠、川木通、八仙草和步骤②所得鱼脑石，武火煎开，转文火煎煮20-40分钟，密封静置10-15小时，取上清液待用；
④将步骤③所得上清液，于80-100℃干热灭菌，密封于塑料瓶中，即得醋饮。
5.根据权利要求4所述的醋饮的制备方法，其特征在于：制备步骤①水的用量是玉米重量的8-12倍（优选的，水的用量是玉米重量的9-11倍，更佳优选的，水的用量是玉米重量的10倍）。
6.根据权利要求4所述的醋饮的制备方法，其特征在于：制备步骤①加水微火慢煮1.5-2.5小时（优选的加水微火慢煮2小时）。
7.根据权利要求4所述的醋饮的制备方法，其特征在于：制备步骤②细末过90-110目筛（优选过100目筛）。
8.根据权利要求4所述的醋饮的制备方法，其特征在于：制备步骤③武火煎开，转文火煎煮25-35分钟（优选武火煎开，转文火煎煮30分钟）。
9.根据权利要求4所述的醋饮的制备方法，其特征在于：制备步骤③密封静置11-14小时（优选的密封静置12小时）。
10.根据权利要求4所述的醋饮的制备方法，其特征在于：制备步骤④于80-100℃干热灭菌3-9分钟（优选的，于85-95℃干热灭菌5-7分钟，更佳优选的，于90℃干热灭菌6分钟）。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410435783.6A CN104172418B (zh) | 2014-08-31 | 2014-08-31 | 一种治疗泌尿性结石的醋饮及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410435783.6A CN104172418B (zh) | 2014-08-31 | 2014-08-31 | 一种治疗泌尿性结石的醋饮及其制备方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104172418A true CN104172418A (zh) | 2014-12-03 |
| CN104172418B CN104172418B (zh) | 2016-01-06 |
Family
ID=51953982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410435783.6A Expired - Fee Related CN104172418B (zh) | 2014-08-31 | 2014-08-31 | 一种治疗泌尿性结石的醋饮及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104172418B (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105567530A (zh) * | 2016-01-30 | 2016-05-11 | 王月水 | 一种具有软化血管之功效的醋饮及其制备方法 |
| WO2020097706A1 (pt) * | 2018-11-13 | 2020-05-22 | Roberto Nardini Antonio | Composição para tratamento e dissolução de cálculos renais |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260202A (zh) * | 1999-08-30 | 2000-07-19 | 张振礼 | 治疗泌尿系结石的药物及其制法 |
| CN100998836A (zh) * | 2006-10-18 | 2007-07-18 | 龚崇明 | 一种适于治疗多器官结石症的药物及其制备方法 |
| CN101732621A (zh) * | 2009-12-25 | 2010-06-16 | 黄毅 | 治疗肾结石的中药 |
| CN102266501A (zh) * | 2011-07-25 | 2011-12-07 | 王疆宏 | 一种结石通茶组合物及其制备方法 |
| CN102895597A (zh) * | 2012-10-17 | 2013-01-30 | 于大鹏 | 一种治疗泌尿系结石的药剂 |
| CN103385954A (zh) * | 2012-05-08 | 2013-11-13 | 陈�田 | 一种用于治疗肾结石的中药组合物 |
-
2014
- 2014-08-31 CN CN201410435783.6A patent/CN104172418B/zh not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1260202A (zh) * | 1999-08-30 | 2000-07-19 | 张振礼 | 治疗泌尿系结石的药物及其制法 |
| CN100998836A (zh) * | 2006-10-18 | 2007-07-18 | 龚崇明 | 一种适于治疗多器官结石症的药物及其制备方法 |
| CN101732621A (zh) * | 2009-12-25 | 2010-06-16 | 黄毅 | 治疗肾结石的中药 |
| CN102266501A (zh) * | 2011-07-25 | 2011-12-07 | 王疆宏 | 一种结石通茶组合物及其制备方法 |
| CN103385954A (zh) * | 2012-05-08 | 2013-11-13 | 陈�田 | 一种用于治疗肾结石的中药组合物 |
| CN102895597A (zh) * | 2012-10-17 | 2013-01-30 | 于大鹏 | 一种治疗泌尿系结石的药剂 |
Non-Patent Citations (2)
| Title |
|---|
| 刘天增: "排尿石汤治疗泌尿***结石98例疗效观察", 《中国实用医药》 * |
| 徐传明: "中医辨证治疗泌尿系结石80例", 《中国当代医药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105567530A (zh) * | 2016-01-30 | 2016-05-11 | 王月水 | 一种具有软化血管之功效的醋饮及其制备方法 |
| WO2020097706A1 (pt) * | 2018-11-13 | 2020-05-22 | Roberto Nardini Antonio | Composição para tratamento e dissolução de cálculos renais |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104172418B (zh) | 2016-01-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103689296B (zh) | 妊娠后期和哺乳期的母羊饲料及其制备方法 | |
| CN102205107B (zh) | 一种治疗十二指肠溃疡的中药制剂及其制备方法 | |
| CN103652360B (zh) | 用于治疗猪副伤寒的饲料及其制备方法 | |
| CN103536826B (zh) | 一种治疗***炎的中药组合物及其制备方法 | |
| CN105213941A (zh) | 一种用于治疗小儿腹泻的中药组合物及其制备方法 | |
| CN104721672A (zh) | 一种治疗粘连性肠梗阻的中药制剂及其制备方法 | |
| CN104172418B (zh) | 一种治疗泌尿性结石的醋饮及其制备方法 | |
| CN103719616B (zh) | 用于治疗猪血痢的饲料及其制备方法 | |
| CN105597057A (zh) | 一种制备治疗急性肾炎的中药组合物散剂的方法 | |
| CN103844164A (zh) | 一种益气补血粥及其制备方法 | |
| CN103099885A (zh) | 具有祛痤疮功能软胶囊及其制备方法 | |
| CN104839483A (zh) | 一种2-3龄鳖的配合饲料及其制备方法 | |
| CN103341151B (zh) | 用于治疗慢性支气管炎的中药 | |
| CN103860976B (zh) | 一种治疗婴幼儿皮炎的药物组合物 | |
| CN103690771B (zh) | 用于治疗羔羊大肠杆菌病的药物及其制备方法 | |
| CN103751533B (zh) | 一种用于***术后的中药外用制剂及其制备方法 | |
| CN110812468B (zh) | 一种手掌参-37味蒙药膏方及其制备方法 | |
| CN107137689A (zh) | 一种治疗更年期综合征的中药组合物 | |
| CN105663828A (zh) | 一种用于治疗产后抑郁症的药物及制备方法 | |
| CN105233048A (zh) | 一种用于治疗精阜炎的中药 | |
| CN104435339A (zh) | 泌尿系补肾排石复方制剂及制法 | |
| CN104524225A (zh) | 一种治疗肾虚型腹部手术后尿潴留的中药 | |
| CN104800687A (zh) | 一种治疗小儿疳积的中药剂及其制备方法 | |
| CN104740396A (zh) | 治疗肾结石的中药剂及制备方法 | |
| CN104258361A (zh) | 一种治疗小儿哮喘的中药组合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhou Jiehua Inventor after: Huang Keji Inventor after: Liu Yong Inventor before: Wang Yueshui |
|
| COR | Change of bibliographic data | ||
| GR01 | Patent grant | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20151214 Address after: Shibei District People's road 266000 Shandong city of Qingdao province No. 4 Applicant after: Zhou Jiehua Address before: 810600 in Qinghai province and county Haidong Haidong Prefecture Public Kawaguchi Town Street 9_2_9 Applicant before: Wang Yueshui |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160106 Termination date: 20190831 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |