CN104098585A - 米尔贝霉素类似物、其制备方法和应用 - Google Patents
米尔贝霉素类似物、其制备方法和应用 Download PDFInfo
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- CN104098585A CN104098585A CN201410321563.0A CN201410321563A CN104098585A CN 104098585 A CN104098585 A CN 104098585A CN 201410321563 A CN201410321563 A CN 201410321563A CN 104098585 A CN104098585 A CN 104098585A
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- 239000003242 anti bacterial agent Substances 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- NZNMSOFKMUBTKW-UHFFFAOYSA-N cyclohexanecarboxylic acid Chemical compound OC(=O)C1CCCCC1 NZNMSOFKMUBTKW-UHFFFAOYSA-N 0.000 description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 2
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- 229950008167 abamectin Drugs 0.000 description 1
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- 238000007605 air drying Methods 0.000 description 1
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- VZFUCHSFHOYXIS-UHFFFAOYSA-N cycloheptane carboxylic acid Natural products OC(=O)C1CCCCCC1 VZFUCHSFHOYXIS-UHFFFAOYSA-N 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- HEDRZPFGACZZDS-MICDWDOJSA-N deuterated chloroform Substances [2H]C(Cl)(Cl)Cl HEDRZPFGACZZDS-MICDWDOJSA-N 0.000 description 1
- 238000011161 development Methods 0.000 description 1
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- QLFZZSKTJWDQOS-YDBLARSUSA-N doramectin Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C3CCCCC3)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C QLFZZSKTJWDQOS-YDBLARSUSA-N 0.000 description 1
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- 244000144972 livestock Species 0.000 description 1
- 239000003120 macrolide antibiotic agent Substances 0.000 description 1
- 229940041033 macrolides Drugs 0.000 description 1
- 229910000357 manganese(II) sulfate Inorganic materials 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- VOZIAWLUULBIPN-LRBNAKOISA-N milbemycin A4 Chemical compound C1C[C@H](C)[C@@H](CC)O[C@@]21O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 VOZIAWLUULBIPN-LRBNAKOISA-N 0.000 description 1
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- AICOOMRHRUFYCM-ZRRPKQBOSA-N oxazine, 1 Chemical compound C([C@@H]1[C@H](C(C[C@]2(C)[C@@H]([C@H](C)N(C)C)[C@H](O)C[C@]21C)=O)CC1=CC2)C[C@H]1[C@@]1(C)[C@H]2N=C(C(C)C)OC1 AICOOMRHRUFYCM-ZRRPKQBOSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dentistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Description
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410321563.0A CN104098585B (zh) | 2014-07-07 | 2014-07-07 | 米尔贝霉素类似物、其制备方法和应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201410321563.0A CN104098585B (zh) | 2014-07-07 | 2014-07-07 | 米尔贝霉素类似物、其制备方法和应用 |
Publications (2)
Publication Number | Publication Date |
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CN104098585A true CN104098585A (zh) | 2014-10-15 |
CN104098585B CN104098585B (zh) | 2016-04-13 |
Family
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Family Applications (1)
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CN201410321563.0A Active CN104098585B (zh) | 2014-07-07 | 2014-07-07 | 米尔贝霉素类似物、其制备方法和应用 |
Country Status (1)
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CN (1) | CN104098585B (zh) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107593728A (zh) * | 2016-07-12 | 2018-01-19 | 江苏龙灯化学有限公司 | 一种杀虫组合物 |
CN110938081A (zh) * | 2019-12-11 | 2020-03-31 | 台州职业技术学院 | 一种大环内酯类新化合物、药物组合物及其制备方法与应用 |
CN113588840A (zh) * | 2021-08-17 | 2021-11-02 | 丽珠集团福州福兴医药有限公司 | 一种检测米尔贝霉素含量的方法 |
CN114634518A (zh) * | 2022-04-02 | 2022-06-17 | 台州职业技术学院 | 两种大环内酯类新化合物、药物组合物及其制备方法和应用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3950360A (en) * | 1972-06-08 | 1976-04-13 | Sankyo Company Limited | Antibiotic substances |
CN101619067A (zh) * | 2009-03-25 | 2010-01-06 | 东北农业大学 | 大环内酯类化合物及其制备方法 |
CN102217611A (zh) * | 2011-04-19 | 2011-10-19 | 浙江农林大学 | 米尔贝霉素树木注干液剂及其用途 |
CN103789339A (zh) * | 2013-11-04 | 2014-05-14 | 浙江海正药业股份有限公司 | 一种产5-酮基米尔贝霉素的链霉菌及生产5-酮基米尔贝霉素的方法 |
-
2014
- 2014-07-07 CN CN201410321563.0A patent/CN104098585B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3950360A (en) * | 1972-06-08 | 1976-04-13 | Sankyo Company Limited | Antibiotic substances |
CN101619067A (zh) * | 2009-03-25 | 2010-01-06 | 东北农业大学 | 大环内酯类化合物及其制备方法 |
CN102217611A (zh) * | 2011-04-19 | 2011-10-19 | 浙江农林大学 | 米尔贝霉素树木注干液剂及其用途 |
CN103789339A (zh) * | 2013-11-04 | 2014-05-14 | 浙江海正药业股份有限公司 | 一种产5-酮基米尔贝霉素的链霉菌及生产5-酮基米尔贝霉素的方法 |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107593728A (zh) * | 2016-07-12 | 2018-01-19 | 江苏龙灯化学有限公司 | 一种杀虫组合物 |
CN110938081A (zh) * | 2019-12-11 | 2020-03-31 | 台州职业技术学院 | 一种大环内酯类新化合物、药物组合物及其制备方法与应用 |
CN110938081B (zh) * | 2019-12-11 | 2021-03-26 | 台州职业技术学院 | 一种大环内酯类新化合物、药物组合物及其制备方法与应用 |
CN113588840A (zh) * | 2021-08-17 | 2021-11-02 | 丽珠集团福州福兴医药有限公司 | 一种检测米尔贝霉素含量的方法 |
CN114634518A (zh) * | 2022-04-02 | 2022-06-17 | 台州职业技术学院 | 两种大环内酯类新化合物、药物组合物及其制备方法和应用 |
CN114634518B (zh) * | 2022-04-02 | 2023-10-24 | 台州职业技术学院 | 两种大环内酯类新化合物、药物组合物及其制备方法和应用 |
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Publication number | Publication date |
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CN104098585B (zh) | 2016-04-13 |
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