CN104083662B - Eliminate collutory and the preparation method of stomatitis type halitosis - Google Patents

Abstract

The present invention is to disclose a kind of collutory eliminating stomatitis type halitosis and preparation method, take off and state the primary raw material of weight proportion and be prepared from: bamboo salt 10 15 parts, melilotus 6 12 parts, Flos Lonicerae 15 20 parts, Herba Lophatheri 4 10 parts, 5 15 parts of Radix Glycyrrhizae, Rhizoma Coptidis 29 parts, Herba Menthae 15 25 parts, 5 10 parts of the Radix Rehmanniae.Having effect of antihalitosis, compared to prior art, therapeutic effect becomes apparent from, and treatment cycle is short, can be with life-time service.The halitosis disease caused by stomatitis is had significant therapeutic effect.

Description

Eliminate collutory and the preparation method of stomatitis type halitosis

Technical field

The invention discloses a kind of collutory, especially eliminate collutory and the preparation method of stomatitis type halitosis.This belongs to traditional Chinese medicine field.

Background technology

Halitosis disease is also referred to as implication or halitosis, it is simply that come out in population makes others be sick of, makes the unpleasant implication of oneself embarrassment.The time that typically lasts for, more than 20 days, i.e. can be identified as halitosis sick.The people of halitosis, the often symptom such as, dry mouth with bitter taste greasy with thick fur, breathe hard uncomfortable in chest, gastrointestinal upset, insomnia and dreamful sleep, constipation.Oral cavity is just as a micro factory, and live about 50,000,000 antibacterials in the inside, and they stay in the corner of darkness and " day and night work ", gnaw and bite food scraps, produces the stink that fermentation is corrupt, and along with breathing comes out.This is also the feel reason that halitosis is heavier later of why wakeing up.The reason causing halitosis is a lot, is generally divided into ectogenic and endogenic, and medically alleged halitosis is sick, is primarily referred to as endogenic.Halitosis is firstly because what oral disease caused, such as gingivitis, gingival hemorrhage, alveolar pyorrhea, a large amount of calculus or dirty dirts or have food impaction, deeply build food residual produces after bacterial decomposition is fermented in hole hydrogen sulfide and methanthiol, pH value is made to reach 7.2, generation is shouted and is stamped and Ammonia, thus produces unpleasant stink.

The main source of halitosis 87% comes from oral cavity, is referred to as " mouth source property halitosis ", is mainly wherein again to be caused by periodontitis, because periodontal bacteria can manufacture " volatility cured compound " in a large number.Hydrogen sulfide is exactly main component therein (having the abnormal smells from the patient of rotten egg).And smoking can clearly cause periodontitis and increase the weight of the development of periodontitis.Smoking itself can reduce salivation, cause xerostomia, loses the buffer capacity of saliva, namely decreases the self-cleaning ability in oral cavity, can increase the weight of halitosis.Even if (having brushed tooth before sleeping, we get up and the most often can feel slightly implication mornings, it is simply that because salivation can reduce during sleep.) also have sub-fraction halitosis to derive from digestive tract, respiratory tract, and long-term smoker often suffer from chronic gastritis, gastric ulcer and chronic pharyngitis, tracheitis, these can cause halitosis.Result of combustion of tobacco itself can discharge niff (pyridine), and this taste would also adhere to, on tooth and oral mucosa, be pumped the most naturally, and abnormal smells from the patient is the heaviest.A lot of people likes smoking, but harm of smoking is the biggest, and halitosis is exactly one therein, and this may be relevant with dietary habit at ordinary times.Certainly, if smoker, smoking would is that the major reason of halitosis.The health illness such as the harmful substances such as the nicotine in Nicotiana tabacum L. can affect the blood circulation of human normal, makes local immunity power decline, final initiation halitosis.Smoking can pollute respiratory tract again, and oral cavity also can be made to become dry, and along with the minimizing of saliva amount, halitosis also can gradually increase the weight of.Additionally, important halitosis reason is not only in smoking, but also it it is the risk factor of various oral disease (including periodontitis, gingivitis, oral mucositis etc.).Often having cigarette smelly in smoker's mouth, impact is social and works, and smoking can make tooth turn yellow, thus is an impediment to attractive in appearance.Therefore healthy also for attractive in appearance, this bad habit of stopping smoking as far as possible.If can not cut out for the moment, then it is noted that oral hygiene at ordinary times, clean oral cavity in time, simultaneously more than drink water, increase oral cavity humidity.

Stomatitis is buccal, tongue limit, palate, and gums etc. occurs ulcer, and around redness is had a pain, and ulceration has erosion.The traditional Chinese medical science is thought by retention of heat in the spleen and stomach, flaming up of heart-fire, asthenic fire floating upward and cause.Medical circle is through clinical and immunological investigation recently, it is believed that its cause of disease is that virus infects, and causes the two-strain of oral ulcer to be respectively human cytomegalovirus and Epstein-Barr virus (epstein-barr virus (EB), a kind of herpesvirus)；Wherein human cytomegalovirus hides T lymph corpuscle in blood, and Epstein-Barr virus is then the B lymph corpuscle hidden in blood, and once flu, emotional stress be big, physical tiredness or deficient in energy, and during immunity difference, virus will be shown effect.Medical research it has also been found that, this kind of virus belongs to primary viral, in being body after people are infected, ensconce subepidermal blood vessel, and breed in nucleus, medical research also indicates that, cold virus and the virus of love can activate the virus hidden in vivo, in other words, when body immune system exception, these viruses can be the most active, and ulcer also can substantially deteriorate.Expert thinks, modern is because of life anxiety, and stress is big, oral ulcer also thus be a kind of " ciril disease " caused because of lifestyle.It is true that according to the clinical observation of doctor, oral ulcer patient has many to fall ill after fatigue.In addition, oral ulcer is recognized as relevant with factors such as heredity, hormone, and as before feminine menstrual, oral ulcer has deterioration situation, climacteric women then case has rising phenomenon, but women's period of pregnancy then sickness rate is relatively low, these phenomenons all show that the generation of ulcer is affected by hormone change.Oral ulcer can occur men and women, old and young, is common with the young and the middle aged.Meanwhile, many with the phenomenon such as constipation, halitosis during morbidity.

In the method that existing Chinese medicine halitosis is sick, publication number CN101181360A(application number 200710114725.3) patent disclose a kind of gargle pharmacy treating halitosis, the crude drug of composition effective ingredient is: the Radix Aucklandiae 10 grams, Flos Caryophylli 6 grams, Herba Pogostemonis 12 grams, the Radix Angelicae Dahuricae 12 grams, Radix Puerariae 30 grams.Publication number CN 101744282A(application number 201010103431.2) patent disclose a kind of rice lotus-root congee treating halitosis and packaging process thereof, the raw material of composition effective ingredient is: 1000 parts of water, rice 50-150 part, Rhizoma Nelumbinis 50-150 part.

Above-mentioned Chinese medicine is invented, and can only alleviate halitosis disease to a certain extent, and DeGrain, more cannot effect a radical cure halitosis sick.To the halitosis caused by stomatitis not particular for therapeutic effect.

Summary of the invention

For the present situation of the halitosis that existing treatment smoking causes, an object of the present invention is to provide the collutory eliminating stomatitis type halitosis, has easily operation, feature evident in efficacy, with low cost.Another object is just to provide the preparation method of above-mentioned collutory.

The above-mentioned purpose of the present invention is achieved through the following technical solutions:

Eliminate the collutory of stomatitis type halitosis, take off and state the primary raw material of weight proportion and be prepared from: bamboo salt 10-15 part, melilotus 6-12 part, Flos Lonicerae 15-20 part, Herba Lophatheri 4-10 part, Radix Glycyrrhizae 5-15 part, Rhizoma Coptidis 2-9 part, Herba Menthae 15-25 part, Radix Rehmanniae 5-10 part.

Above-mentioned preparation method, preferred version is, takes off and states the primary raw material of weight proportion and be prepared from: bamboo salt 11-14 part, melilotus 7-11 part, Flos Lonicerae 16-19 part, Herba Lophatheri 5-8 part, Radix Glycyrrhizae 7-13 part, Rhizoma Coptidis 4-7 part, Herba Menthae 17-23 part, Radix Rehmanniae 6-9 part.

Above-mentioned preparation method, preferred version is, takes off and states the primary raw material of weight proportion and be prepared from: bamboo salt 12 parts, melilotus 9 parts, Flos Lonicerae 18 parts, Herba Lophatheri 6 parts, 10 parts of Radix Glycyrrhizae, Rhizoma Coptidis 5 parts, Herba Menthae 20 parts, 8 parts of the Radix Rehmanniae.

The preparation method of above-mentioned collutory, is characterized in that, step is as follows:

(1) Herba Lophatheri is dried rear pulverization, cross mesh sieve, obtain bamboo leaf powder；

(2) Herba Menthae is cleaned making beating, with hot-water soak, filter, obtain filtrate；

(3) by melilotus, Flos Lonicerae, Flos Caryophylli, Radix Glycyrrhizae and Rhizoma Coptidis mix homogeneously, stand-by with three grades of rice wine moistening；

(4) joining in step (2) gained filtrate by step (3) gained mixture, after intense fire is fried open, fire of larding speech with literary allusions is decocted, and adds step (1) gained bamboo leaf powder, stand, take supernatant stand-by after truce；

(5) bamboo salt is joined in step (4) gained supernatant, simmer, after being sufficiently stirred for, be aided with pharmaceutically acceptable carrier package and i.e. obtain collutory.

Above-mentioned preparation method, preferred version is: step (1) crosses 80-120 mesh sieve (preferably 90-110 mesh sieve, mistake 100 mesh sieve more preferably).

Above-mentioned preparation method, preferred version is: step (2) pours the hot water (hot water of preferably 75 DEG C-85 DEG C, more preferably pour 80 DEG C of hot water into) of 70 DEG C-90 DEG C into.

Above-mentioned preparation method, preferred version is: step (3) moistening 30-60 minute (preferred moistening 40-50 minute, moistening more preferably 45 minutes).

Above-mentioned preparation method, preferred version is: step (4) slow fire decocts 40-60 minute (preferably decocting 45-55 minute, pan-fried 50 minutes more preferably).

Above-mentioned preparation method, preferred version is: step (4) stands 20-50 minute (preferably standing 30-40 minute, standing more preferably 35 minutes).

Above-mentioned preparation method, preferred version is: step (5) simmers 30-50(and preferably simmers 35-45 minute, more preferably simmer 40 minutes).

Using method: for making the present invention reach optimum therapeuticing effect, uses application clear water when gargling to gargle, then, containing collutory, gargles more than 1 minute, do not gargle with clear water after having gargled again.Advising and the concrete condition every day of oneself selects to use 3-5 time according to abiding by of doctor, each 20ml, 3 days is a course for the treatment of.

The pharmacological effect of each crude drug is respectively as follows:

Bamboo salt: being to be evaporated brine day in the triennial QINGZHU of loading, two ends are sealed with natural loess, with pinaster as fuel, the material extracting after 1000 DEG C～1500 DEG C of high-temperature calcinations.Bamboo salt is with natural sea salt as raw material, with bamboo, Colophonium, loess as adjuvant, repeatedly fires and forms.Function: bamboo salt energy detoxication and toxicant eliminating function, bamboo salt can be removed the various body fluid of whole body such as enteral stool, entrance saliva, gastric juice, blood, lymph fluid, bile, urine, toxin excretes (so perspiration, urine is micro-salty) by feat of powerful power of impregnation and osmotic pressure.Bamboo salt energy balanced human, bamboo salt can the nutritive equilibrium of effective balanced human, acid-base balance, equilibrium between yin and yang, metabolism balances.Bamboo salt is high-energy food, and bamboo salt can stablize sufficient radioactive source infrared ray.Play the peculiar effect of far infrared.Bamboo salt is basic food, and modern is owing to eating the acid foods such as public hazards food, processing food, meat too much, so body constitution is substantially all shows as acidity.Bamboo salt is basic food, thus acidic physique can be accomplished effective, directly improve.Also it is the important prerequisite effected a radical cure of chronic condition of disease.

Melilotus: genus pulse family, biennial herb is high 40-100 centimetre.Originating in northeast, south China, various places, southwest, remaining each province is usually by cultivation.It is born in hillside, riverbank, roadside, chiltern meadow.Bitter in the mouth, light, cool in nature, nontoxic.There is effect of heat-clearing and toxic substances removing, be used for treating skin scar, red wind, dysentery with red and white feces, gonorrhea.

Flos Lonicerae: sweet in the mouth, cold in nature.Return lung, the heart, stomach warp.There is heat-clearing and toxic substances removing, effect of wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.

Radix Glycyrrhizae: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, limbs pain, carbuncle sore tumefacting virus.

Herba Menthae: acrid in the mouth, cool in nature.Return lung, Liver Channel.There is wind-dispelling heat-dissipating, refresh oneself, throat, rash, effect of resolving depression.For dizziness of having a headache, conjunctival congestion and swelling pain, pharyngalgia celostomia, toothache, measles without adequate eruption, urticaria pruritus, hypochondriac pain due to stagnation of liverQI gastral cavity is swollen.

Rhizoma Coptidis: this product is the dry rhizome of ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall.Meridian distribution of property and flavor: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication.Tying mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomit acid regurgitation.

The Radix Rehmanniae: another name Radix Rehmanniae, for the tuber of scrophulariaceae rehmannia glutinosa plant.Herbaceos perennial, height 10-30 centimetre, close by the long pubescence of canescence many cells and glandular hair.Meridian distribution of property and flavor: sweet, cold.GUIXIN, liver, kidney channel.There is clearing away heat and cooling blood effect join the army blood for warming febrile disease, high fever coma, xerostomia crimson tongue.Controlling the convalescent stage of febrile disease, waste heat not to the greatest extent, hinder, night fever abating at dawn, red tongue rapid pulse person by cloudy liquid.Can be used for controlling warm febrile disease to join the army blood, heat in blood poison is contained, and hematemesis and epistaxis, macule purple is black；Thirsty for Tianjin wound, interior-heat is quenched one's thirst.Control epidemic febrile disease impairment of YIN, dryness of the intestine constipation.

Herba Lophatheri: this product is the dry stem and leaf of grass Herba Lophatheri.Meridian distribution of property and flavor: sweet, light, cold.GUIXIN, stomach, small intestine meridian.Function cures mainly: clearing heat and relieving fidgetness, diuresis.For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.

Compared with prior art, the technical advantage of the present invention is embodied in:

1, medical material used by the present invention does not has toxicity, and the health mechanism for sufferer does not results in damage, and audient crowd is wide, is suitable for child and old people takes.

2, bright the used medical material relative inexpensiveness of this law, compared with prior art the bright obtained collutory cost of this law is cheaper.

3, the therapeutic effect of the present invention becomes apparent from compared to prior art, therapeutic effect, and treatment cycle is short, does not has obvious sequela, can be with life-time service.

Detailed description of the invention

Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited by this.

Embodiment 1Eliminate the collutory of stomatitis type halitosis, take off and state the primary raw material of weight proportion and be prepared from (every part takes 10g): bamboo salt 10 parts, melilotus 6 parts, Flos Lonicerae 15 parts, Herba Lophatheri 4 parts, 5 parts of Radix Glycyrrhizae, Rhizoma Coptidis 2 parts, Herba Menthae 15 parts, 5 parts of the Radix Rehmanniae.

The collutory preparation process eliminating stomatitis type halitosis is as follows:

(1) Herba Lophatheri is dried rear pulverization, cross 80 mesh sieves, obtain bamboo leaf powder；

(2) Herba Menthae is cleaned making beating, with 70 DEG C of hot-water soaks, filter, obtain filtrate；

(3) by melilotus, Flos Lonicerae, Flos Caryophylli, Radix Glycyrrhizae and Rhizoma Coptidis mix homogeneously, with three grades of rice wine moistening 30 minutes, stand-by；

(4) joining in step (2) gained filtrate by step (3) gained mixture, after intense fire is fried open, fire of larding speech with literary allusions is decocted 40 minutes, adds step (1) gained bamboo leaf powder, stand 20 minutes, take supernatant stand-by after truce；

(5) bamboo salt is joined in step (4) gained supernatant, simmer 30 minutes, after being sufficiently stirred for, be aided with pharmaceutically acceptable carrier package and i.e. obtain collutory.

Model case oneLee so-and-so, man, 31 years old.Suffers from stomatitis, stomatitis disease is not too paid close attention to by patient, seeks medical advice the most in time, along with stomatitis is the most serious, sufferer occurs in that the symptom of halitosis, with dense implication when speaking, with rotten-egg odour, have a strong impact on the sufferer normal talk with other people, sufferer then arrives hospital and seeks medical advice, while treatment stomatitis, under the suggestion of doctor, use the collutory obtained by this enforcement 1, in order to treat the symptom sick by the halitosis caused by stomatitis.

Using collutory obtained by the present embodiment 1, one day 3 times, each 20ml, 3 days is a course for the treatment of, after using 2 courses for the treatment of, sufferer implication is the most thin out, and rotten-egg odour alleviates, after being continuing with 1 course for the treatment of, sufferer implication recovers normal, and rotten-egg odour disappears, and halitosis symptom is cured.

Embodiment 2Eliminate the collutory of stomatitis type halitosis, take off and state the primary raw material of weight proportion and be prepared from (every part takes 15g): bamboo salt 15 parts, melilotus 12 parts, Flos Lonicerae 20 parts, Herba Lophatheri 10 parts, 15 parts of Radix Glycyrrhizae, Rhizoma Coptidis 9 parts, Herba Menthae 25 parts, 10 parts of the Radix Rehmanniae.

The collutory preparation process eliminating stomatitis type halitosis is as follows:

(1) Herba Lophatheri is dried rear pulverization, cross 120 mesh sieves, obtain bamboo leaf powder；

(2) Herba Menthae is cleaned making beating, with 90 DEG C of hot-water soaks, filter, obtain filtrate；

(3) by melilotus, Flos Lonicerae, Flos Caryophylli, Radix Glycyrrhizae and Rhizoma Coptidis mix homogeneously, with three grades of rice wine moistening 60 minutes, stand-by；

(4) joining in step (2) gained filtrate by step (3) gained mixture, after intense fire is fried open, fire of larding speech with literary allusions is decocted 60 minutes, adds step (1) gained bamboo leaf powder, stand 50 minutes, take supernatant stand-by after truce；

(5) bamboo salt is joined in step (4) gained supernatant, simmer 50 minutes, after being sufficiently stirred for, be aided with pharmaceutically acceptable carrier package and i.e. obtain collutory.

Embodiment 3Eliminate the collutory of stomatitis type halitosis, take off and state the primary raw material of weight proportion and be prepared from (every part takes 20g): bamboo salt 11 parts, melilotus 7 parts, Flos Lonicerae 16 parts, Herba Lophatheri 5 parts, 7 parts of Radix Glycyrrhizae, Rhizoma Coptidis 4 parts, Herba Menthae 17 parts, 6 parts of the Radix Rehmanniae.

The collutory preparation process eliminating stomatitis type halitosis is as follows:

(1) Herba Lophatheri is dried rear pulverization, cross 90 mesh sieves, obtain bamboo leaf powder；

(2) Herba Menthae is cleaned making beating, with 75 DEG C of hot-water soaks, filter, obtain filtrate；

(3) by melilotus, Flos Lonicerae, Flos Caryophylli, Radix Glycyrrhizae and Rhizoma Coptidis mix homogeneously, with three grades of rice wine moistening 40 minutes, stand-by；

(4) joining in step (2) gained filtrate by step (3) gained mixture, after intense fire is fried open, fire of larding speech with literary allusions is decocted 45 minutes, adds step (1) gained bamboo leaf powder, stand 30 minutes, take supernatant stand-by after truce；

(5) bamboo salt is joined in step (4) gained supernatant, simmer 35 minutes, after being sufficiently stirred for, be aided with pharmaceutically acceptable carrier package and i.e. obtain collutory.

Typical case two: king so-and-so, man, 19 years old, student enrollment.Liking pungent food, suffer from stomatitis, stomatitis is not the most cured, and sufferer the symptom of halitosis occurs due to stomatitis, and oral inflammation aggravates, and with implication, implication distributes rotten stench.Seek medical advice to hospital, under the suggestion of doctor of traditional Chinese medicine, employ collutory obtained in the present embodiment 3.

Using collutory obtained by this enforcement 3 one day 3 times, a 20ml, three days is a course for the treatment of, and after using 1 course for the treatment of, implication substantially alleviates, and after being continuing with 2 courses for the treatment of, implication recovers normal, and stomatitis makes moderate progress, and sufferer self-induction therapeutic effect is good.

Embodiment 4Eliminate the collutory of stomatitis type halitosis, take off and state the primary raw material of weight proportion and be prepared from (every part takes 25g): bamboo salt 14 parts, melilotus 11 parts, Flos Lonicerae 19 parts, Herba Lophatheri 8 parts, 13 parts of Radix Glycyrrhizae, Rhizoma Coptidis 7 parts, Herba Menthae 23 parts, 9 parts of the Radix Rehmanniae.

The collutory preparation process eliminating stomatitis type halitosis is as follows:

(1) Herba Lophatheri is dried rear pulverization, cross 110 mesh sieves, obtain bamboo leaf powder；

(2) Herba Menthae is cleaned making beating, with 85 DEG C of hot-water soaks, filter, obtain filtrate；

(3) by melilotus, Flos Lonicerae, Flos Caryophylli, Radix Glycyrrhizae and Rhizoma Coptidis mix homogeneously, with three grades of rice wine moistening 50 minutes, stand-by；

(4) joining in step (2) gained filtrate by step (3) gained mixture, after intense fire is fried open, fire of larding speech with literary allusions is decocted 55 minutes, adds step (1) gained bamboo leaf powder, stand 40 minutes, take supernatant stand-by after truce；

(5) bamboo salt is joined in step (4) gained supernatant, simmer 45 minutes, after being sufficiently stirred for, be aided with pharmaceutically acceptable carrier package and i.e. obtain collutory.

Embodiment 5Eliminate the collutory of stomatitis type halitosis, take off and state the primary raw material of weight proportion and be prepared from (every part takes 30g): bamboo salt 12 parts, melilotus 9 parts, Flos Lonicerae 18 parts, Herba Lophatheri 6 parts, 10 parts of Radix Glycyrrhizae, Rhizoma Coptidis 5 parts, Herba Menthae 20 parts, 8 parts of the Radix Rehmanniae.

The collutory preparation process eliminating stomatitis type halitosis is as follows:

(1) Herba Lophatheri is dried rear pulverization, cross 100 mesh sieves, obtain bamboo leaf powder；

(2) Herba Menthae is cleaned making beating, with 80 DEG C of hot-water soaks, filter, obtain filtrate；

(3) by melilotus, Flos Lonicerae, Flos Caryophylli, Radix Glycyrrhizae and Rhizoma Coptidis mix homogeneously, with three grades of rice wine moistening 45 minutes, stand-by；

(4) joining in step (2) gained filtrate by step (3) gained mixture, after intense fire is fried open, fire of larding speech with literary allusions is decocted 50 minutes, adds step (1) gained bamboo leaf powder, stand 35 minutes, take supernatant stand-by after truce；

(5) bamboo salt is joined in step (4) gained supernatant, simmer 40 minutes, after being sufficiently stirred for, be aided with pharmaceutically acceptable carrier package and i.e. obtain collutory.

Test example 1 :The clinical practice of the collutory of embodiment 5 gained elimination stomatitis type halitosis: in January ,-2014 in July, 2012,400 example patients are screened in 5 hospitals, max age 65 years old, minimal ages 18 years old, the halitosis all suffering from causing because of stomatitis is sick, sufferer is randomly divided into two groups, experimental group 300 people, matched group 100 people, experimental group uses the collutory obtained by this enforcement 5, and matched group uses other medicines, observe 6 days time limits, test the first 1 day symptom to patient comprehensively to check, periodically check inquiry patient body situation and impression during experiment, and make a record.

Using method: for making the present invention reach optimum therapeuticing effect, uses application clear water when gargling to gargle, then, containing collutory, gargles more than 1 minute, do not gargle with clear water after having gargled again.Advising and the concrete condition every day of oneself selects to use 4 times according to abiding by of doctor, each 20ml, 3 days is a course for the treatment of.Effective: malaise symptoms alleviates or partial disappearance.Cure: malaise symptoms disappears, and without recurrence.Invalid: malaise symptoms is unchanged or recurs.Result is as shown in the table:

As it can be seen from table 1 therapeutic effect: take the healing 260 example (86.7%) of embodiment 5 product, effective 36 examples (12%), invalid 4 examples (1.3%), total effective rate 98.7%.And take the healing 35 example (35%) of other products, and effective 15 examples (15%), invalid 50 examples (50%), total effective rate 50%.Can be seen that taking the effect of embodiment 5 product is substantially better than and takes other products.

Finally it should be noted that, embodiment is the detailed description of the invention that the present invention is optimum, it is not limited to the present invention, although the present invention being described in detail with reference to previous embodiment, for a person skilled in the art, technical scheme described in foregoing embodiments still can be modified by it, or wherein portion of techniques feature is carried out equivalent.All within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.

Claims (3)

1. Eliminate the collutory of stomatitis type halitosis, it is characterized in that, take off the raw material stating weight proportion: bamboo salt 10-15 part, melilotus 6-12 part, Flos Lonicerae 15-20 part, Herba Lophatheri 4-10 part, Radix Glycyrrhizae 5-15 part, Rhizoma Coptidis 2-9 part, Herba Menthae 15-25 part, Radix Rehmanniae 5-10 part；Bamboo salt: being to be evaporated brine day in the triennial QINGZHU of loading, two ends are sealed with natural loess, with pinaster as fuel, the material extracting after 1000 DEG C～1500 DEG C of high-temperature calcinations；Rhizoma Coptidis: for the dry rhizome of ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall；Herba Lophatheri: for the dry stem and leaf of grass Herba Lophatheri.

2. Collutory according to claim 1, is characterized in that, takes off the raw material stating weight proportion: bamboo salt 11-14 part, melilotus 7-11 part, Flos Lonicerae 16-19 part, Herba Lophatheri 5-8 part, Radix Glycyrrhizae 7-13 part, Rhizoma Coptidis 4-7 part, Herba Menthae 17-23 part, Radix Rehmanniae 6-9 part.

3. Collutory according to claim 1, is characterized in that, takes off the raw material stating weight proportion: bamboo salt 12 parts, melilotus 9 parts, Flos Lonicerae 18 parts, Herba Lophatheri 6 parts, 10 parts of Radix Glycyrrhizae, Rhizoma Coptidis 5 parts, Herba Menthae 20 parts, 8 parts of the Radix Rehmanniae.