CN104027576A - Preparation for treating third-stage internal hemorrhoid and capable of promoting blood circulation and eliminating dampness and production method of preparation - Google Patents
Preparation for treating third-stage internal hemorrhoid and capable of promoting blood circulation and eliminating dampness and production method of preparation Download PDFInfo
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Abstract
The invention discloses a preparation for treating third-stage internal hemorrhoid and capable of promoting blood circulation and eliminating dampness. The preparation is produced from the following major raw materials in parts by weight: 15-35 parts of radix rehmanniae, 3-9 parts of coptis chinensis, 3-6 parts of rhizoma cimicifugae, 6-12 parts of pagodatree pod, 6-15 parts of herba schizonepetae, 9-16 parts of polygonatum odoratum, 8-12 parts of paniculate swallowwort root, 5-15 parts of pericarpium papaveris (stir-heated with rice vinegar), 9-12 parts of fructus psoraleae, 5-15 parts of pagodatree flower bud, 5-16 parts of gentiana macrophylla, 6-12 parts of bunge cherry seed and 18-30 parts of purslane. The preparation is wide in source of the selected medicinal materials, simple in preparation method and low in production cost; compared with the existing medicines for treating haemorrhoids, the preparation is developed specially for the third-stage internal hemorrhoid, and is remarkable in curative effect.
Description
Technical field
The present invention relates to Chinese medicine field, particularly relate to a kind of stageⅢhemorrhoid invigorate blood circulation damp eliminating prescription and preparation method.
background technology
Hemorrhoid are a kind of common property diseases that endanger person health.According to the difference of morbidity position, hemorrhoid can be divided into internal hemorrhoid, external hemorrhoid and mixed hemorrhoid.Blood stasis is positioned at be called " internal hemorrhoid " of anus the inside mucosa, is called " external hemorrhoid " near being positioned at anal orifice inner side, and the two has is called " mixed hemorrhoid ".
Internal hemorrhoid is more common a kind of in hemorrhoid, also larger to the harm of human body.According to the difference of the pathological change of internal hemorrhoid and development degree, often internal hemorrhoid is divided into clinically to three phases.First phase internal hemorrhoid symptom is lighter, and under sight glass, visible mucosa is the nodositas differing in size, and matter is soft, and color is red; While referring to inspection, the softness of pressing, mucous membrane surface is very thin, is easily frayed and hemorrhage during stool, and stool is normal to be with blood or to bleed, because of blood stasis small volume, therefore do not deviate from outside anus.Second phase, internal hemorrhoid was attached most importance to compared with first phase, and blood stasis is larger, and hemorrhoid mucosal tissue is weak, while exerting oneself defecation, blood stasis emerges in outside anus, can get back to voluntarily anal after an action of the bowels, during stool, excrement piece friction hemorrhoid mucomembranous surface, causes and has blood in stool, and does not have blood in stool and can be toilet paper band blood, bleeds, penetrates blood not etc.StageⅢhemorrhoid is the late stage of internal hemorrhoid.Owing to suffering from the internal hemorrhoid time longer, blood stasis increases, after an action of the bowels blood stasis emerge in anus outer, even cough, exert oneself, walk and also can emerge in outside anus during work, must send anal back to hands, or just can send anal back to after rest.
StageⅢhemorrhoid is first phase the most serious in hemorrhoid, and blood stasis volume increases, and has connective tissue proliferation, mucosa thickening, kermesinus, rough surface.After deviating from, can not naturally reset, need return or put down sleeping rear beginning with hand push can reset.If blood stasis is often deviate from, will cause sphincter dilatation, every running into when exerting oneself, cough, walk and squatting down, all may deviate from.As failed after deviating from, reset in time, due to sphincterismus, extruding, so that obstruction of blood return, the congested swelling of blood stasis, inside has thrombosis, and very person is downright bad, sharp ache, this is strangulated internal hemorrhoid.StageⅢhemorrhoid symptom is more serious, mainly contain: 1. Zhi core is deviate from: stageⅢhemorrhoid, because blood stasis volume increases, is subject to the extruding of feces during defecation, make it separated with flesh layer and deviate from outside anus gradually, sometimes be that 1-2 blood stasis are deviate from simultaneously, be whole blood stasis sometimes and deviate from simultaneously with mucous membrane of rectum.StageⅢhemorrhoid symptom is heavier, needs to return with hand push, or lie up after deviating from, and can reset.Serious symptom person, deviating from during except defecation, all firmly, walking, cough, sneeze, squat down etc., all may deviate from.2. have blood in stool: in defecation or hemorrhage after an action of the bowels, color is scarlet, stool surface is with a small amount of blood sometimes, or toilet paper is incarnadined, sometimes for bleeding or penetrating blood.Due to feces galling mucosa, or too exert oneself during because of defecation, intravascular pressure increases, so that cirso-angiorrhexis, has spurting hemorrhage in the time of just.3. pain: stageⅢhemorrhoid is more serious, because Zhi core increases, more difficult when defecation, can cause the abnormal pain in anus position; Sometimes Zhi core is deviate from outside anus, is difficult to self-resetting, and sense can aggravate the pain.4. mucus flows out: because stageⅢhemorrhoid is internal hemorrhoid in late period, because of Sphincter ani chalasia, often have secretions to be flowed out by anus.When the lighter defecates, flow out, severe one does not flow out during defecation naturally yet, pollutes underwear, and patient is extremely inconvenient.When internal hemorrhoid is deviate from, secretions is more.5. pruritus: because of secretions or the stimulation of deviating from blood stasis, make anus moist unclean around, eczema and pruritus occur, scratch where it itches sometimes because internal hemorrhoid is deviate from and caused because of reflection.In addition, stageⅢhemorrhoid, due to the generation of symptoms such as having blood in stool, also can cause the syndromes such as anemia, chronic colitis, intestinal cancer.Therefore, stageⅢhemorrhoid is very harmful to people's health, and patient is partner treatment actively.
Dietary habit at ordinary times of the main and people of stageⅢhemorrhoid, daily life system etc. have much relations, also relevant with people's attention degree, and some patient is at the beginning time and pay no attention to, active treatment not, to such an extent as to the state of an illness is more and more serious, develops into stageⅢhemorrhoid.Therefore, in daily life, people should form good daily life system rule and the custom of defecation regularly, after finding to suffer from hemorrhoid, should early treatment, and avoid aggravation, endanger the healthy of oneself.
Publication number is CN 101229257A(application number 200810009070.8) Chinese patent literature a kind of by name " the fumigation and wash method hip bath preparation that the outer incarceration of a kind of external curing stageⅢhemorrhoid core anus resets " disclosed, it is comprised of medical materials such as HUTUISHU root, full Folium Callicarpae Formosanae, Alumen, Natrii Sulfas, Cortex Phellodendri, Herba Equiseties Hiemalis.Application publication number is CN 103585595A(application number 201310469957.6) Chinese patent literature a kind of by name " a kind of Chinese medicine preparation for the treatment of internal hemorrhoid " disclosed, 6～15 parts of Semen Juglandis for this Chinese medicine preparation, 6～15 parts of Fructus Crataegis, 6～15 parts, Rhizoma Zingiberis Recens and 6～15 parts of fried forming of brown sugar.
In a word, Chinese medicine is being obtained certain effect in treatment aspect internal hemorrhoid, but also has some problems: in the medicine of existing treatment hemorrhoid, oral medicine and external water preparation, powder therapeutic effect are unsatisfactory, more do not reach the effect of radical cure, therefore need further to improve.
Summary of the invention
In order to make up above-mentioned deficiency, the object of the present invention is to provide a kind of stageⅢhemorrhoid evident in efficacy, easy to use invigorate blood circulation damp eliminating prescription and preparation method, its dosage form is unguentum, can make up the deficiencies in the prior art, there is the effect of the damp eliminating of invigorating blood circulation, thereby reach the effect of radical cure stageⅢhemorrhoid.
Technical scheme of the present invention is:
The stageⅢhemorrhoid damp eliminating prescription of invigorating blood circulation, takes off the primary raw material of stating weight proportion and is prepared from: Radix Rehmanniae 15-35 part, Rhizoma Coptidis 3-9 part, Rhizoma Cimicifugae 3-6 part, Fructus Sophorae 6-12 part, Herba Schizonepetae 6-15 part, Rhizoma Polygonati Odorati 9-16 part, Radix Cynanchi Paniculati 8-12 part, Pericarpium Papaveris (vinegar stir-fry) 5-15 part, Fructus Psoraleae 9-12 part, Flos Sophorae Immaturus 5-15 part, Radix Gentianae Macrophyllae 5-16 part, Semen Pruni 6-12 part, Herba Portulacae 18-30 part.
The stageⅢhemorrhoid damp eliminating prescription of invigorating blood circulation, preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: Radix Rehmanniae 20-30 part, Rhizoma Coptidis 5-7 part, Rhizoma Cimicifugae 4-5 part, Fructus Sophorae 8-10 part, Herba Schizonepetae 9-11 part, Rhizoma Polygonati Odorati 10-14 part, Radix Cynanchi Paniculati 9-11 part, Pericarpium Papaveris (vinegar stir-fry) 8-12 part, Fructus Psoraleae 10-12 part, Flos Sophorae Immaturus 8-12 part, Radix Gentianae Macrophyllae 7-12 part, Semen Pruni 8-10 part, Herba Portulacae 22-26 part.
The stageⅢhemorrhoid damp eliminating prescription of invigorating blood circulation, the scheme being more preferably is, takes off the primary raw material of stating weight proportion and is prepared from: 25 parts, the Radix Rehmanniae, 6 parts of Rhizoma Coptidis, 4.5 parts of Rhizoma Cimicifugaes, 9 parts of the Fructuss Sophorae, 10 parts of Herba Schizonepetae, 12 parts of Rhizoma Polygonati Odorati, 10 parts of Radix Cynanchi Paniculatis, 10 parts of Pericarpium Papaveriss (vinegar stir-fry), 11 parts of Fructus Psoraleaes, 10 parts of the Flos Sophorae Immaturus, 10 parts of Radix Gentianae Macrophyllae, 9 parts of Semen Prunis, 24 parts of Herba Portulacaes.
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, Radix Cynanchi Paniculati and the Flos Sophorae Immaturus are placed in to Oleum Sesami and soak 15-25 hour, with marmite, with slow fire, boil 25-65 minute, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Fructus Sophorae, Herba Schizonepetae, Pericarpium Papaveris (vinegar stir-fry) and Fructus Psoraleae mixed powder are broken into fine powder, cross 90-130 mesh sieve;
(3) will Rhizoma Coptidis, Rhizoma Polygonati Odorati, Radix Gentianae Macrophyllae, Semen Pruni and Herba Portulacae decoct with water twice after mixing, water consumption be crude drug gross weight 3.5-6.5 doubly, 1.6-2.2 hour for the first time, 0.8-1.2 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain prescription unguentum.
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preferred scheme is that step (1) is placed in Oleum Sesami and soaks 18-22 hour (preferably 20 hours).
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preferred scheme is that step (1) boils 40-50 minute (preferably 45 minutes) with marmite with slow fire.
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preferred scheme is that step (2) is crossed 100-120 mesh sieve (preferably 110 mesh sieves).
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preferred scheme is, step (3) water consumption is the 4-6 doubly (preferably 5 times) of crude drug gross weight.
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preferred scheme is, step (3) 1.8-2 hour for the first time (preferably 1.9 hours).
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preferred scheme is, step (3) 0.9-1.1 hour for the second time (preferably 1 hour).
Best using method: for making the present invention reach best therapeutic effect, make unguentum, every day 2 times, be applied in right amount affected part, 7 days courses for the treatment of in sooner or later getting.
The pharmacological effect of each crude drug is respectively:
The Radix Rehmanniae: another name Radix Rehmanniae is the tuber of scrophulariaceae rehmannia glutinosa plant.Nature and flavor: sweet in the mouth, cold.Return through GUIXIN liver, kidney channel.Effect: there is clearing away heat and cooling blood effect for the warm febrile disease blood of joining the army, high fever coma, xerostomia crimson tongue.Cure mainly: can be used for controlling the warm febrile disease blood of joining the army, heat in blood poison is contained, hematemesis and epistaxis, macule purple is black.
Rhizoma Coptidis: base is former: be the dry rhizome of ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall.Nature and flavor: hardship, cold.Gui Jing: GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication.Cure mainly: for cold and heat, tie mutually damp and hot middle resistance, feeling of fullness vomiting.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Rhizoma Cimicifugae: base is former: be the dry rhizome of ranunculaceae plant C.heracleifolia, Cimicifuga Dahurica or Rhizoma Cimicifugae.Nature and flavor: pungent, micro-sweet, be slightly cold.Gui Jing: return lung, spleen, stomach, large intestine channel.Effect: deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.Cure mainly: for headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome is sent out speckle; Proctoptosis, uterine prolapse.
The Fructus Sophorae: base is former: this product is the dry mature fruit of leguminous plant Chinese scholartree.Nature and flavor: hardship, cold.Gui Jing: return liver, large intestine channel.Effect: clearing away heat-fire, cooling blood for hemostasis.Cure mainly: for intestinal heat, have blood in stool, hemorrhoid are swollen hemorrhage, liver-heat headache, dizzy conjunctival congestion.
Herba Schizonepetae: base is former: this product is the dry aerial parts of labiate Herba Schizonepetae.Nature and flavor: acrid in the mouth, tepor.Gui Jing: return lung, Liver Channel.Effect: the loose wind that induces sweat, rash.Cure mainly: for flu, headache, measles, rubella, skin infection from the beginning of.
Rhizoma Polygonati Odorati: base is former: this product is the dry rhizome of liliaceous plant Rhizoma Polygonati Odorati.Nature and flavor: sweet in the mouth, is slightly cold.Gui Jing: attach to the lung and stomach meridians.Effect: nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.Cure mainly: for lung stomach-Yin wound, cough caused by dryness-heat, swallows in thirsty, and interior-heat is quenched one's thirst.
Radix Cynanchi Paniculati: base is former: this product is the dry root and rhizome of asclepiadaceae plant Radix Cynanchi Paniculati.Nature and flavor: pungent, temperature.Gui Jing: return liver, stomach warp.Effect: the removing dampness of dispeling the wind, antalgesic-antipruritic.Cure mainly: for rheumatic arthralgia, stomachache distension, toothache, lumbago, injury from falling down; Urticaria, eczema.
Pericarpium Papaveris: base is former: be the drying and ripening shell of bloodroot Semen Papaveris.Nature and flavor: sour in the mouth, puckery is flat; Poisonous.Gui Jing: return lung, large intestine, kidney channel.Effect: astringe the lung, astringing intestine to stop diarrhea, pain relieving.Cure mainly: for chronic cough, chronic diarrhea, proctoptosis, epigastric pain.
Fructus Psoraleae: base is former: be the dry mature fruit of legumes psoraleae.Nature and flavor: pungent, bitter, temperature.Gui Jing: return kidney, spleen channel.Effect: warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.Cure mainly: for impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.
The Flos Sophorae Immaturus: another name: white Chinese scholartree, Flos Sophorae, Flos Sophorae Immaturus, Chinese scholartree seed.Base is former: be the alabastrum of leguminous plant Chinese scholartree.Nature and flavor: cold nature, bitter in the mouth.Effect: cooling blood for hemostasis, purging liver-fire.Cure mainly: for having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, haematemesis, epistaxis, liver-heat conjunctival congestion, have a headache dizzy.
Radix Gentianae Macrophyllae: base is former: be the dry root of gentianaceae plant Radix Gentianae Macrophyllae, gentiana straminea maxim, gentiana crassicaulis Duthie or Gentiana dahurica.Nature and flavor: acrid in the mouth, hardship, flat.Gui Jing: return stomach, liver, gallbladder meridian.Effect: wind-damp dispelling, clearing away damp-heat, stopping numbness pain.Cure mainly: for rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, day food in one's mouth hectic fever, infantile malnutrition heating.
Semen Pruni: base is former: be the dry mature seed of rosaceous plant Prunus humilis, strongly fragrant Lee or Prunus pedunculata Maxim..Nature and flavor: acrid in the mouth, bitter, sweet, flat.Gui Jing: return spleen, large intestine, small intestine meridian.Effect: moisturize laxation, the therapeutic method to keep the adverse QI flowing downwards, diuretic.Cure mainly: for intestine-dryness due to consumption of fluid, stagnation of QI due to dyspepsia, abdominal distention constipation, edema, beriberi, dysuria.
Herba Portulacae: base is former: be the dry aerial parts of portulacaceous plant Herba Portulacae.Nature and flavor: acid, cold.Gui Jing: return liver, large intestine channel.Effect: heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly: for toxic-heat and blood stasis, carbuncle furuncle, eczema, erysipelas, snake bite and insect sting, has blood in stool, hemorrhoidal bleeding, metrostaxis.
Prescription of the present invention develops for stageⅢhemorrhoid specially, and stageⅢhemorrhoid is had to good therapeutic effect, has the effect of the damp eliminating of invigorating blood circulation, and can fundamentally treat stageⅢhemorrhoid, rear and difficult recurrence.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1the stageⅢhemorrhoid damp eliminating prescription of invigorating blood circulation, takes off the primary raw material of stating weight proportion and is prepared from (getting 10g for every part): 15 parts, the Radix Rehmanniae, 3 parts of Rhizoma Coptidis, 3 parts of Rhizoma Cimicifugaes, 6 parts of the Fructuss Sophorae, 6 parts of Herba Schizonepetae, 9 parts of Rhizoma Polygonati Odorati, 8 parts of Radix Cynanchi Paniculatis, 5 parts of Pericarpium Papaveriss (vinegar stir-fry), 9 parts of Fructus Psoraleaes, 5 parts of the Flos Sophorae Immaturus, 5 parts of Radix Gentianae Macrophyllae, 6 parts of Semen Prunis, 18 parts of Herba Portulacaes.
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, Radix Cynanchi Paniculati and the Flos Sophorae Immaturus are placed in to Oleum Sesami and soak 15 hours, with marmite, with slow fire, boil 25 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Fructus Sophorae, Herba Schizonepetae, Pericarpium Papaveris (vinegar stir-fry) and Fructus Psoraleae mixed powder are broken into fine powder, cross 90 mesh sieves;
(3) will after Rhizoma Coptidis, Rhizoma Polygonati Odorati, Radix Gentianae Macrophyllae, Semen Pruni and Herba Portulacae mixing, decoct with water twice, water consumption is 3.5 times of crude drug gross weight, 1.6 hours for the first time, 0.8 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal ointment.
embodiment 2the stageⅢhemorrhoid damp eliminating prescription of invigorating blood circulation, takes off the primary raw material of stating weight proportion and is prepared from (getting 20g for every part): 35 parts, the Radix Rehmanniae, 9 parts of Rhizoma Coptidis, 6 parts of Rhizoma Cimicifugaes, 12 parts of the Fructuss Sophorae, 15 parts of Herba Schizonepetae, 16 parts of Rhizoma Polygonati Odorati, 12 parts of Radix Cynanchi Paniculatis, 15 parts of Pericarpium Papaveriss (vinegar stir-fry), 12 parts of Fructus Psoraleaes, 15 parts of the Flos Sophorae Immaturus, 16 parts of Radix Gentianae Macrophyllae, 12 parts of Semen Prunis, 30 parts of Herba Portulacaes.
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, Radix Cynanchi Paniculati and the Flos Sophorae Immaturus are placed in to Oleum Sesami and soak 25 hours, with marmite, with slow fire, boil 65 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Fructus Sophorae, Herba Schizonepetae, Pericarpium Papaveris (vinegar stir-fry) and Fructus Psoraleae mixed powder are broken into fine powder, cross 130 mesh sieves;
(3) will after Rhizoma Coptidis, Rhizoma Polygonati Odorati, Radix Gentianae Macrophyllae, Semen Pruni and Herba Portulacae mixing, decoct with water twice, water consumption is 6.5 times of crude drug gross weight, 2.2 hours for the first time, 1.2 hours for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal ointment.
model case one: all XX, female, 67 years old.Suffer from hemorrhoid before patient's readme, so because take medicine and do not draw attention at ordinary times always, but it is undesirable to take medicine recently effect, more difficult during defecation, just in, there are a large amount of bloodstain, and have the symptom of bleeding, after several days, when patient defecates, Zhi core is deviate from outside anus, be difficult to self-resetting, need to return with hand push, and now during defecation anus place pain hard to bear, medicine before taking is again invalid.Use the present embodiment 2 gained stageⅢhemorrhoids damp eliminating prescription of invigorating blood circulation, adopt every day 2 times, in sooner or later getting, be applied in right amount affected part, 7 days courses for the treatment of.Use 2 days, patient's malaise symptoms is alleviated to some extent, pain relief during defecation; Use 5 days, patient's malaise symptoms is clearly better, and the symptom of having blood in stool obviously alleviates; Continue to use 3 days, patient's readme malaise symptoms disappears completely, between the operating period, without any discomfort symptom, produces.
embodiment 3the stageⅢhemorrhoid damp eliminating prescription of invigorating blood circulation, takes off the primary raw material of stating weight proportion and is prepared from (getting 30g for every part): 20 parts, the Radix Rehmanniae, 5 parts of Rhizoma Coptidis, 4 parts of Rhizoma Cimicifugaes, 8 parts of the Fructuss Sophorae, 9 parts of Herba Schizonepetae, 10 parts of Rhizoma Polygonati Odorati, 9 parts of Radix Cynanchi Paniculatis, 8 parts of Pericarpium Papaveriss (vinegar stir-fry), 10 parts of Fructus Psoraleaes, 8 parts of the Flos Sophorae Immaturus, 7 parts of Radix Gentianae Macrophyllae, 8 parts of Semen Prunis, 22 parts of Herba Portulacaes.
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, Radix Cynanchi Paniculati and the Flos Sophorae Immaturus are placed in to Oleum Sesami and soak 18 hours, with marmite, with slow fire, boil 40 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Fructus Sophorae, Herba Schizonepetae, Pericarpium Papaveris (vinegar stir-fry) and Fructus Psoraleae mixed powder are broken into fine powder, cross 100 mesh sieves;
(3) will after Rhizoma Coptidis, Rhizoma Polygonati Odorati, Radix Gentianae Macrophyllae, Semen Pruni and Herba Portulacae mixing, decoct with water twice, water consumption is 4 times of crude drug gross weight, 1.8 hours for the first time, 0.9 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal ointment.
embodiment 4the stageⅢhemorrhoid damp eliminating prescription of invigorating blood circulation, takes off the primary raw material of stating weight proportion and is prepared from (getting 40g for every part): 30 parts, the Radix Rehmanniae, 7 parts of Rhizoma Coptidis, 5 parts of Rhizoma Cimicifugaes, 10 parts of the Fructuss Sophorae, 11 parts of Herba Schizonepetae, 14 parts of Rhizoma Polygonati Odorati, 11 parts of Radix Cynanchi Paniculatis, 12 parts of Pericarpium Papaveriss (vinegar stir-fry), 12 parts of Fructus Psoraleaes, 12 parts of the Flos Sophorae Immaturus, 12 parts of Radix Gentianae Macrophyllae, 10 parts of Semen Prunis, 26 parts of Herba Portulacaes.
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, Radix Cynanchi Paniculati and the Flos Sophorae Immaturus are placed in to Oleum Sesami and soak 22 hours, with marmite, with slow fire, boil 50 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Fructus Sophorae, Herba Schizonepetae, Pericarpium Papaveris (vinegar stir-fry) and Fructus Psoraleae mixed powder are broken into fine powder, cross 120 mesh sieves;
(3) will after Rhizoma Coptidis, Rhizoma Polygonati Odorati, Radix Gentianae Macrophyllae, Semen Pruni and Herba Portulacae mixing, decoct with water twice, water consumption is 6 times of crude drug gross weight, 2 hours for the first time, 1.1 hours for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal ointment.
model case two: Lee XX, man, 35 years old, writer.Patient's readme is lived always irregular at ordinary times, the recent months writing of everyday staying up late, goes to toilet several times and starts to have blood in stool recently, and flowed a lot of blood, wipe also only incessantly, anus place is burning pain also, sometimes in lavatory once sitting for a long time, the state of an illness of going to toilet is now more serious, can feel and have a meat to deviate from from the inside outside anus, be difficult to return again voluntarily, remove examination in hospital, be diagnosed as stageⅢhemorrhoid.Use the present embodiment 4 gained stageⅢhemorrhoids damp eliminating prescription of invigorating blood circulation, adopt every day 2 times, in sooner or later getting, be applied in right amount affected part, 7 days courses for the treatment of.Use 2 days, patient's symptom of having blood in stool is obviously alleviated, and the scorching hot distending pain sense of crissum disappears; Use 4 days, patient Zhi core is deviate from phenomenon and is reduced, and malaise symptoms obviously improves; Continue to use 3 days, patient's malaise symptoms disappears completely, self-induction recovery from illness.
embodiment 5the stageⅢhemorrhoid damp eliminating prescription of invigorating blood circulation, takes off the primary raw material of stating weight proportion and is prepared from (getting 50g for every part): 25 parts, the Radix Rehmanniae, 6 parts of Rhizoma Coptidis, 4.5 parts of Rhizoma Cimicifugaes, 9 parts of the Fructuss Sophorae, 10 parts of Herba Schizonepetae, 12 parts of Rhizoma Polygonati Odorati, 10 parts of Radix Cynanchi Paniculatis, 10 parts of Pericarpium Papaveriss (vinegar stir-fry), 11 parts of Fructus Psoraleaes, 10 parts of the Flos Sophorae Immaturus, 10 parts of Radix Gentianae Macrophyllae, 9 parts of Semen Prunis, 24 parts of Herba Portulacaes.
The invigorate blood circulation preparation method of damp eliminating prescription of above-mentioned stageⅢhemorrhoid, preparation process is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, Radix Cynanchi Paniculati and the Flos Sophorae Immaturus are placed in to Oleum Sesami and soak 20 hours, with marmite, with slow fire, boil 45 minutes, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Fructus Sophorae, Herba Schizonepetae, Pericarpium Papaveris (vinegar stir-fry) and Fructus Psoraleae mixed powder are broken into fine powder, cross 110 mesh sieves;
(3) will after Rhizoma Coptidis, Rhizoma Polygonati Odorati, Radix Gentianae Macrophyllae, Semen Pruni and Herba Portulacae mixing, decoct with water twice, water consumption is 5 times of crude drug gross weight, 1.9 hours for the first time, 1 hour for the second time, collecting decoction, filters, and it is 1.10(45 ℃ that filtrate is concentrated into relative density) clear paste;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal ointment.
experimental example 1the invigorate blood circulation clinical practice of damp eliminating prescription of embodiment 5 gained stageⅢhemorrhoids: in February, 2009-2011 year November, screen 160 routine patients in 5 hospitals, women's 83 examples wherein, male's 77 examples.Before test 6 days, this crowd is carried out to Continuous Observation, record symptom and variation, be divided at random two groups, experimental group and matched group, experimental group is taken embodiment 5 products obtained therefroms, and matched group is taken other medicine conventional medicines such as () hemorrhoid capsule, SANQI HUAZHI WAN.Using method is: every day 2 times, in sooner or later getting, be applied in right amount affected part, 7 days courses for the treatment of.Curative effect situation criterion: cure: use a course for the treatment of of this product, have blood in stool, the malaise symptoms such as pain disappears completely; Effective: use a course for the treatment of of this product, malaise symptoms alleviates or part disappears; Invalid: use a course for the treatment of of this product, malaise symptoms is unchanged.Result is as shown in table 1.
The invigorate blood circulation compliance test result of damp eliminating prescription of table 1: embodiment 5 gained stageⅢhemorrhoids
Therapeutic effect: cure 74 examples (74%), effective 21 examples (21%), invalid 5 examples (5%), total effective rate 95%.Successful is better than matched group.
Between the operating period, self-induction symptom and other symptom variation are as shown in table 2.
Table 2:
Oleum Sesami has the effect of loosening bowel to relieve constipation, removing toxic substances, granulation promoting, can effectively treat dryness of the intestine constipation, ulcer, skin ulcer swollen etc.Select Oleum Sesami and medicine to carry out compatibility, the effect of the more effective performance medicine of energy, makes the present invention have the effect of the damp eliminating of invigorating blood circulation, and stageⅢhemorrhoid is had to better therapeutic effect, thereby reach the object of healing.Use 3 days, more than 51% patient's symptom is improved, the disappearance of having blood in stool, pain relief; Use 6 days, more than 72% patient's malaise symptoms improves, and Zhi core is deviate from symptom and reduced; Use 9 days, more than 94% patient's malaise symptoms improves, the recovery from illness of some patients were self-induction.Experimental group is used 9 days, and effective percentage can reach 94%, and matched group is only 73%.
Finally it should be noted that, embodiment is the specific embodiment of optimum of the present invention, be not limited to the present invention, although the present invention is had been described in detail with reference to previous embodiment, for a person skilled in the art, its technical scheme that still can record aforementioned each embodiment is modified, or part technical characterictic is wherein equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. the stageⅢhemorrhoid damp eliminating prescription of invigorating blood circulation, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Radix Rehmanniae 15-35 part, Rhizoma Coptidis 3-9 part, Rhizoma Cimicifugae 3-6 part, Fructus Sophorae 6-12 part, Herba Schizonepetae 6-15 part, Rhizoma Polygonati Odorati 9-16 part, Radix Cynanchi Paniculati 8-12 part, Pericarpium Papaveris (vinegar stir-fry) 5-15 part, Fructus Psoraleae 9-12 part, Flos Sophorae Immaturus 5-15 part, Radix Gentianae Macrophyllae 5-16 part, Semen Pruni 6-12 part, Herba Portulacae 18-30 part.
2. the stageⅢhemorrhoid according to claim 1 damp eliminating prescription of invigorating blood circulation, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Radix Rehmanniae 20-30 part, Rhizoma Coptidis 5-7 part, Rhizoma Cimicifugae 4-5 part, Fructus Sophorae 8-10 part, Herba Schizonepetae 9-11 part, Rhizoma Polygonati Odorati 10-14 part, Radix Cynanchi Paniculati 9-11 part, Pericarpium Papaveris (vinegar stir-fry) 8-12 part, Fructus Psoraleae 10-12 part, Flos Sophorae Immaturus 8-12 part, Radix Gentianae Macrophyllae 7-12 part, Semen Pruni 8-10 part, Herba Portulacae 22-26 part.
3. the stageⅢhemorrhoid according to claim 1 damp eliminating prescription of invigorating blood circulation, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: 25 parts, the Radix Rehmanniae, 6 parts of Rhizoma Coptidis, 4.5 parts of Rhizoma Cimicifugaes, 9 parts of the Fructuss Sophorae, 10 parts of Herba Schizonepetae, 12 parts of Rhizoma Polygonati Odorati, 10 parts of Radix Cynanchi Paniculatis, 10 parts of Pericarpium Papaveriss (vinegar stir-fry), 11 parts of Fructus Psoraleaes, 10 parts of the Flos Sophorae Immaturus, 10 parts of Radix Gentianae Macrophyllae, 9 parts of Semen Prunis, 24 parts of Herba Portulacaes.
4. according to the invigorate blood circulation preparation method of damp eliminating prescription of the arbitrary described stageⅢhemorrhoid of claim 1-3, it is characterized in that, step is as follows:
(1) Radix Rehmanniae, Rhizoma Cimicifugae, Radix Cynanchi Paniculati and the Flos Sophorae Immaturus are placed in to Oleum Sesami and soak 15-25 hour, with marmite, with slow fire, boil 25-65 minute, boil to micro-withered, oil dripping Cheng Zhuwei degree, endure afterwards that to wait medicine oil temperature to be down to 30 ℃ of elimination medicinal residues standby;
(2) Fructus Sophorae, Herba Schizonepetae, Pericarpium Papaveris (vinegar stir-fry) and Fructus Psoraleae mixed powder are broken into fine powder, cross 90-130 mesh sieve;
(3) will Rhizoma Coptidis, Rhizoma Polygonati Odorati, Radix Gentianae Macrophyllae, Semen Pruni and Herba Portulacae decoct with water twice after mixing, water consumption be crude drug gross weight 3.5-6.5 doubly, 1.6-2.2 hour for the first time, 0.8-1.2 hour for the second time, collecting decoction, filters, and it is 1.10 clear paste that filtrate is concentrated into relative density;
(4) step (1)-(3) gains are mixed, stir, be concentrated in right amount, obtain Chinese medicinal ointment.
5. preparation method according to claim 4, is characterized in that: step (1) is placed in Oleum Sesami and soaks 18-22 hour (preferably 20 hours).
6. preparation method according to claim 4, is characterized in that: step (1) boils 40-50 minute (preferably 45 minutes) with marmite with slow fire.
7. preparation method according to claim 4, is characterized in that: step (2) is crossed 100-120 mesh sieve (preferably 110 mesh sieves).
8. preparation method according to claim 4, is characterized in that: step (3) water consumption is 4-6 times (preferably 5 times) of crude drug gross weight.
9. preparation method according to claim 4, is characterized in that: step (3) 1.8-2 hour for the first time (preferably 1.9 hours).
10. preparation method according to claim 4, is characterized in that: step (3) 0.9-1.1 hour for the second time (preferably 1 hour).
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| CN105213977A (en) * | 2015-10-24 | 2016-01-06 | 孙桂芝 | A kind of hemorrhoid external plaster for the treatment of damp heat downward flowing type |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213977A (en) * | 2015-10-24 | 2016-01-06 | 孙桂芝 | A kind of hemorrhoid external plaster for the treatment of damp heat downward flowing type |
| CN105213977B (en) * | 2015-10-24 | 2019-03-01 | 百草堂医药股份有限公司 | A kind of hemorrhoid external plaster for treating damp heat downward flowing type |
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