CN103690940A - Compound dimetridazole premix for preventing and treating poultry enterovirus syndrome - Google Patents
Compound dimetridazole premix for preventing and treating poultry enterovirus syndrome Download PDFInfo
- Publication number
- CN103690940A CN103690940A CN201310728696.5A CN201310728696A CN103690940A CN 103690940 A CN103690940 A CN 103690940A CN 201310728696 A CN201310728696 A CN 201310728696A CN 103690940 A CN103690940 A CN 103690940A
- Authority
- CN
- China
- Prior art keywords
- dimetridazole
- mixing agent
- percent
- lysozyme
- premix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a compound dimetridazole premix for preventing and treating the poultry enterovirus syndrome. The premix is prepared by uniformly mixing the following components in percentage by weight: 10 to 30 percent of dimetridazole, 4 to 10 percent of neomycin sulfate, 2 to 8 percent of decoquinate econazole nitrate, 10 to 30 percent of lysozyme, 0.5 to 5 percent of etamsylate, 3 to 10 percent of lactic acid TMP and the balance of pharmaceutically applicable auxiliary material. According to the invention, the novel high-efficiency anticoccidial drug decoquinate econazole nitrate, the dimetridazole and the neomycin sulfate which have a special curative effect on intestinal infection, the lysozyme with effects of resisting to bacteria, resisting to viruses, diminishing inflammation, relieving pain and repairing intestinal mucosa, the high-efficiency hemostatics etamsylate and the drug synergist are compounded into a compound preparation; and the compound dimetridazole premix has a high-efficiency treatment effect on the poultry enterovirus syndrome. The compound dimetridazole premix has a reasonable and scientific formula, is simple to prepare, has wide application and can be used as a priority drug for preventing and treating the poultry enterovirus syndrome.
Description
Technical field
The present invention relates to a kind of fowl medicine, particularly relate to a kind of for preventing and treating the syndromic compound recipe dimetridazole pre-mixing agent of birds intestinal poison.
Background technology
At present, along with the intensive development of the high density of aquaculture, area in China's aquaculture prosperity, there is a large problem, no matter being that ground is flat supports or online flat supporting, no matter be broiler or laying hen, Ji Qunzhong all ubiquity a kind of take contain the incomplete feedstuff of digestion in diarrhoea, feces or be that the red feces of Fructus Kaki, feed intake decline, lose weight, dehydration, the price of deed decline, cut open simultaneously and examine the disease that has Fructus Lycopersici esculenti sample content etc. be feature in intestinal.At present this disease is generally popular, although mortality rate is not high, the recessive economic loss causing is huge, and by raiser, to be takeed for be that " dyspepsia " or mistaken diagnosis are small intestinal coccidiosis.Research shows, this disease is not caused by single cause of disease, but a kind of syndrome being caused by multi-pathogenesis, called after " intestinal toxicity syndrome ".The comprehensive disease that intestinal toxicity syndrome is a kind of intestinal mucosa inflammation being caused by multi-pathogenesis, thicken, come off, hemorrhage, downright bad etc. changes, primary disease all can occur throughout the year, but occur large time more with summer, autumn, winter and weather and difference variation, any age in days can occur, particularly the chicken of 15 ~ 90 ages in days is multiple, 30 ages in days are occurred frequently, and laying hen also can occur, and broiler occurrence frequency is higher.
The etiological analysis of intestinal toxicity syndrome:
(1) infectiousness factor: mainly refer to virus, antibacterial, parasite.
1. viral infection: the infection of virus all can become the inducement that intestinal intestinal toxicity syndrome occurs as: arc reovirus virus, adenovirus, parvovirus, crown, colyliform, Astrovirus, these viruses cause enteritis, the absorption function of infringement intestinal, destroy intestinal mucosa, after infecting, broiler chicken classical symptom causes obstacle to cause dysplasia for digesting and assimilating, growth retardation and diarrhoea etc.
2. antibacterial infects: some common pathogenic bacterium, the necrotic enteritis causing as Salmonella, bacillus perfringens, clostridieum welchii, the microbial ulcerative enteritis of alcohol shuttle, escherichia coli, anaerobe etc. are also the causes of disease that causes enterotoxic syndrome of meat chicken, these bacterium are by stimulating intestinal mucosa, make enterokinesia accelerate to strengthen, Digestive system is discharged and is increased, and feed link is crossed gastral time shorten, causes dysentery, diarrhoea, punishment in advance.
3. the infection of parasite (main finger small intestinal, caecum coccidiosis): parasite is also the major reason that causes intestinal intestinal toxicity syndrome, and its mechanism of bringing out is roughly:
Coccidiosis is amount reproduction on intestinal mucosa, cause intestinal mucosa to thicken, the pathological changes such as seriously come off, almost make feedstuff not digest and assimilate, the absorption of moisture is also obviously reduced, although broiler great quantity of water drinking simultaneously, but bad because absorbing, a large amount of water sample loose stool of discharging are taken away moisture and are caused dehydration phenomenon, and this is to cause that broiler feces is thinning, in excrement with not digesting one of reason of feedstuff.
Coccidiosis is Fast-propagation in intestinal mucosa cells, oxygen consumption is large, cause mucous membrane of small intestine tissue to produce a large amount of lactic acid, intestinal pH value is seriously reduced, probiotics falls sharply, coccidiosis and harmful bacteria are mutually collaborative, cause pathogenic reinforcement, electrolyte is run off in a large number, particularly potassium ion, can cause cardiac excitability excessively to strengthen, accelerate primary disease mortality rate.
(2) non-pathogenic factor:
1. each anatoxic impact: external toxin may be present in each material compositions such as feedstuff, drinking-water, endotoxin produces these toxin by escherichia coli, clostridieum welchii, alcohol clostridium occurs corrupt decomposition, after disintegrate, discharge a large amount of harmful substances, after being absorbed by body, there is self poisoning in these harmful substances, thus the situation of stupor exhaustion death after appearance excitement clinically.
2. vitamin in feedstuff, energy and the impact of protein height on broiler, in feedstuff nutrition too abundant, sickness rate is higher, symptom is more serious.
3. the impact of various stressors (reload, it is large etc. that in feedstuff, corn moisture too much, heat is adopted the water yield).
4. density is excessive, and humidity is excessive, draws badly.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art part, provide a kind of efficient, quick-acting, treating both the principal and secondary aspects of a disease for preventing and treating the compound recipe dimetridazole pre-mixing agent of birds intestinal toxicity syndrome.
The technical scheme that the present invention solves its technical problem is: a kind of for preventing and treating the compound recipe dimetridazole pre-mixing agent of birds intestinal toxicity syndrome, this pre-mixing agent is made by following component mix homogeneously by weight percentage: dimetridazole 10～30%, polygynax 4～10%, Kui oxygen quinoline ester 2～8%, lysozyme 10～30%, etamsylate 0.5～5%, lactic acid TMP3～10%, surplus is pharmaceutically applicable adjuvant.
Described pre-mixing agent is made by following component mix homogeneously by weight percentage: dimetridazole 15～25%, polygynax 5～8%, Kui oxygen quinoline ester 5～6%, lysozyme 14～25%, etamsylate 2～4%, lactic acid TMP4～8%, surplus is pharmaceutically applicable adjuvant.
Described pre-mixing agent is made by following component mix homogeneously by weight percentage: dimetridazole 18～22%, polygynax 7～9%, Kui oxygen quinoline ester 3～7%, lysozyme 16～27%, etamsylate 1～3%, lactic acid TMP7～9%, surplus is pharmaceutically applicable adjuvant.
Described pre-mixing agent is made by following component mix homogeneously by weight percentage: dimetridazole 20%, polygynax 6%, Kui oxygen quinoline ester 4%, and lysozyme 20%, etamsylate 1.5%, lactic acid TMP5%, surplus is pharmaceutically applicable adjuvant.
Described pharmaceutically applicable adjuvant is at least a kind of in starch, sucrose, anhydrous glucose, oral glucose, preferably anhydrous glucose.
The characteristic of various medicines and composition principle in the present invention:
Dimetridazole: dimetridazole is wide spectrum anaerobe resistant and antiprotozoal drug, coccidiosis is had to certain inhibitory action, be mainly used in the trichomonacide of fowl vibrio hepatitis, gangrenosum acne tissue, enterohepatitis, fowl etc., the trichomonacide of cattle is also had to good curative effect.These product also can be used as growth promoter, in order to promote the production of pig, chicken and to improve food conversion ratio.This product toxicity is low, and animal better tolerance, without carcinogenic teratogenesis, is rapidly absorbed in intestinal, is distributed in each tissue, through biliary tract, enters intestinal, liver circulation.In fowl carcass, after oxidation, reductive metabolism, excrete.Residue in trunk, after 48h or after the cooking, the overwhelming majority is destroyed.In soil, decompose also very fast, therefore can not cause the pollution to environment.
Polygynax: polygynax is a kind of aminoglycoside antibiotics.This product has good antibacterial action to enterobacteriaceae lactobacteriaceaes such as staphylococcus (methicillin-sensitivity strain), corynebacterium, escherichia coli, Klebsiella, Proteus, poor to each group B streptococcus, streptococcus pneumoniae, Enterococcus isoreactivity.The oral intestinal infection that can be used for responsive Pseudomonas of neomycin.
Kui oxygen quinoline ester: Kui oxygen quinoline ester plays a role at the asexual reproductive phase of coccidiosis, enters after coccidiosis spore cell, and by disturbing, DNA is synthetic stops it to grow, coccidiosis life cycle start in early days play a role, thereby avoid poultry intestinal tract sustain damage.This drug absorption is fast, can reach the valid density of anticoccidial in 1 hour, the concentration level that peaks after 3 days.Deccox belongs to efficient coccidiostat, not yet finds that at present any coccidiosis has drug resistance to Kui oxygen quinoline ester.
Lysozyme: lysozyme (lysozyme) claims again muramidase (muramidase) or N-acetylmuramide lycanohydrlase (N-acetylmuramide glycanohydrlase) is a kind of alkaline enzyme that can be hydrolyzed mucopolysaccharide in pathogenic bacterium.Mainly, by the-acetylmuramic acid in destruction cell wall and the β-Isosorbide-5-Nitrae glycosidic bond between NAG, make the insoluble mucopolysaccharide of cell wall resolve into solubility glycopeptide, cause cell wall rupture content to be overflowed and make bacterolysis.Lysozyme also can the direct combination with electronegative virus protein, forms double salt with DNA, RNA, apoprotein, makes virally inactivated.Can be used as a kind of natural infection material with bactericidal action.There are antibacterial, antiviral, hemostasis, reducing swelling and alleviating pain and accelerate the effects such as organized renewing function.
Etamsylate: etamsylate can increase platelet counts, and strengthen its coherency and adhesive force, promote platelet to discharge blood coagulation activity material, shorten clotting time, accelerate blood clot retraction.In addition, still there is the capillary resistance of enhancing, reduce its permeability, reduce the effects such as blood oozes out.This product anastalsis is rapid, and the effect in latter 1 hour of quiet note gets final product peaking, the sustainable 4-6 hour of drug effect.Clinically applicable to various hemorrhage, as hemorrhage in perioperatively, digestive tract hemorrhage etc.Also can share with other hemorrhage (as vitamin K).
Lactic acid TMP: the lactate that this product is TMP, its mechanism of action is anti-bacteria dihydrofolate reductase, makes dihydrofoilic acid can not be reduced into tetrahydrofolic acid, stops the synthetic of bacterial nucleic acid.Trimethoprim lactate is combined use with sulphonamides, Tetracyclines, penicillins, erythromycin, gentamycin, fluoroquinolones, can strengthen the antibacterial activity of original medicine, and can also reduce the generation of Resistant strain.
Comprehensive drug feature: in view of the cause of disease of intestinal toxicity syndrome is complicated, will regularly prevent in multiple season for this disease, should treat in time after morbidity.Though this disease causes by many factors, it is the main cause that causes morbidity that coccidiosis occurs, so should be specifically noted that prevention coccidiosis on veterinary clinic; Meanwhile, in feedstuff, should keep enough vitamin A and vitamin Es, to improve the resistance of body.Because of this disease early period of origination, the general non-evident sympton of chicken group, so in warm rainy high humidity season, give special heed to chicken group state, notes abnormalities, and makes a definite diagnosis early.In order to reach good therapeutic effect, when the treatment of this disease, must consider various pathogenic factors, in conjunction with the coefficient result of its multi-pathogenesis, according to the principle of the etiological treatment of suiting the medicine to the illness, to reach good therapeutic effect.The present invention be to intestinal toxicity syndrome various pathogenic factors carry out putting forward on the basis of large quantity research, and take the pathological material of disease of various places to carry out a large amount of drug sensitivity tests, by a series of clinical trial, carried out abundant checking, by three-dimensional prescription, many infection reason considerations is careful, do not allow a kind of pathogenic microorganism slip through the net; The reason of harm body is considered comprehensively, and antiinflammatory, antibacterial, antiviral, hemostasis, reparation intestinal mucosa etc. also can effectively be controlled secondary infection simultaneously.
Beneficial effect: the present invention adopts new and effective coccidiostat Kui oxygen quinoline ester, the dimetridazole and the polygynax that intestinal infection are had to special efficacy, and there is the lysozyme of antibacterial, antiviral, anti-inflammatory analgetic, reparation intestinal mucosa effect, high-effective hemostatic thing etamsylate and medicament synergistic agent are re-dubbed compound preparation, and birds intestinal toxicity syndrome is had to efficient therapeutical effect.The present invention fills a prescription rationally, science, preparation simple, be widely used, and can be used as the choice drug of prevention and treatment birds intestinal toxicity syndrome.
The specific embodiment
Below in conjunction with preferred embodiment, the present invention will be further described.
Embodiment 1: according to following proportioning, take respectively raw material: dimetridazole 20g, polygynax 6g, Kui oxygen quinoline ester 4g, lysozyme 20g, etamsylate 1.5g, lactic acid TMP5g, add anhydrous glucose to 100g, mix homogeneously, makes the specific compound recipe dimetridazole pre-mixing agent that is used for the treatment of birds intestinal toxicity syndrome of a kind of tool.Described raw material is commercially available prod.
Embodiment 2: according to following proportioning, take respectively raw material: dimetridazole 11g, polygynax 9g, Kui oxygen quinoline ester 2g, lysozyme 30g, etamsylate 1g, lactic acid TMP8g, add anhydrous glucose to 100g, mix homogeneously, makes the specific compound recipe dimetridazole pre-mixing agent that is used for the treatment of birds intestinal toxicity syndrome of a kind of tool.Described raw material is commercially available prod.
Embodiment 3: according to following proportioning, take respectively raw material: dimetridazole 30g, polygynax 4g, Kui oxygen quinoline ester 7g, lysozyme 12g, etamsylate 4g, lactic acid TMP4g, add anhydrous glucose to 100g, mix homogeneously, makes the specific compound recipe dimetridazole pre-mixing agent that is used for the treatment of birds intestinal toxicity syndrome of a kind of tool.Described raw material is commercially available prod.
Embodiment 4: according to following proportioning, take respectively raw material: dimetridazole 16g, polygynax 7g, Kui oxygen quinoline ester 5.5g, lysozyme 23g, etamsylate 2.5g, lactic acid TMP7g, add starch, oral glucose to 100g, mix homogeneously, makes the specific compound recipe dimetridazole pre-mixing agent that is used for the treatment of birds intestinal toxicity syndrome of a kind of tool.The weight ratio of described starch, oral glucose is 1:1.Described raw material is commercially available prod.
Embodiment 5: according to following proportioning, take respectively raw material: dimetridazole 24g, polygynax 6g, Kui oxygen quinoline ester 5.8g, lysozyme 15g, etamsylate 3.5g, lactic acid TMP4.5g, with sucrose, anhydrous glucose to 100g, mix homogeneously, makes the specific compound recipe dimetridazole pre-mixing agent that is used for the treatment of birds intestinal toxicity syndrome of a kind of tool.The weight ratio of described sucrose, anhydrous glucose is 1:2.Described raw material is commercially available prod.
Embodiment 6: according to following proportioning, take respectively raw material: dimetridazole 21g, polygynax 8g, Kui oxygen quinoline ester 6.5g, lysozyme 26g, etamsylate 2g, lactic acid TMP7.5g, add starch, anhydrous glucose and oral glucose to 100g, mix homogeneously, makes the specific compound recipe dimetridazole pre-mixing agent that is used for the treatment of birds intestinal toxicity syndrome of a kind of tool.The weight ratio of described starch, anhydrous glucose and oral glucose is 1:1:1.Described raw material is commercially available prod.
Using method: be watered 400 jin of drinking-water with this product medicine 100g, use (control after feeding night drinking-water after 2 hours administering effect best) in night, be used in conjunction 3～5 days, spice doubles, and prevention reduces by half.
Effect: be applicable to prevention and the treatment of birds intestinal toxicity syndrome, show as clinically in diarrhoea, feces, contain the incomplete feedstuff of digestion or be that the red feces of Fructus Kaki, feed intake decline, lose weight, dehydration, the price of deed decline, cut open simultaneously and examine that in intestinal, to have Fructus Lycopersici esculenti sample content etc. be the disease of feature.With after can effectively control generation and the development of intestinal toxicity syndrome, use and can effectively control hemafecia in two days, improve food conversion ratio.
Above-mentioned preferred embodiment is to the description of carrying out for preventing and treating the compound recipe dimetridazole pre-mixing agent of birds intestinal toxicity syndrome; illustrative and not restrictive; can enumerate several embodiment according to institute's limited range; therefore in the variation and the modification that do not depart under general idea of the present invention, within should belonging to protection scope of the present invention.
Claims (6)
1. one kind for preventing and treating the compound recipe dimetridazole pre-mixing agent of birds intestinal toxicity syndrome, it is characterized in that: this pre-mixing agent is made by following component mix homogeneously by weight percentage: dimetridazole 10～30%, polygynax 4～10%, Kui oxygen quinoline ester 2～8%, lysozyme 10～30%, etamsylate 0.5～5%, lactic acid TMP3～10%, surplus is pharmaceutically applicable adjuvant.
2. compound recipe dimetridazole pre-mixing agent according to claim 1, it is characterized in that: described pre-mixing agent is made by following component mix homogeneously by weight percentage: dimetridazole 15～25%, polygynax 5～8%, Kui oxygen quinoline ester 5～6%, lysozyme 14～25%, etamsylate 2～4%, lactic acid TMP4～8%, surplus is pharmaceutically applicable adjuvant.
3. compound recipe dimetridazole pre-mixing agent according to claim 1, it is characterized in that: described pre-mixing agent is made by following component mix homogeneously by weight percentage: dimetridazole 18～22%, polygynax 7～9%, Kui oxygen quinoline ester 3～7%, lysozyme 16～27%, etamsylate 1～3%, lactic acid TMP7～9%, surplus is pharmaceutically applicable adjuvant.
4. compound recipe dimetridazole pre-mixing agent according to claim 1, it is characterized in that: described pre-mixing agent is made by following component mix homogeneously by weight percentage: dimetridazole 20%, polygynax 6%, Kui oxygen quinoline ester 4%, lysozyme 20%, etamsylate 1.5%, lactic acid TMP5%, surplus is pharmaceutically applicable adjuvant.
5. according to the compound recipe dimetridazole pre-mixing agent described in claim 1-4 any one, it is characterized in that: described pharmaceutically applicable adjuvant is at least a kind of in starch, sucrose, anhydrous glucose, oral glucose.
6. compound recipe dimetridazole pre-mixing agent according to claim 5, is characterized in that: described pharmaceutically applicable adjuvant is anhydrous glucose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310728696.5A CN103690940B (en) | 2013-12-26 | 2013-12-26 | Compound dimetridazole premix for preventing and treating poultry enterovirus syndrome |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310728696.5A CN103690940B (en) | 2013-12-26 | 2013-12-26 | Compound dimetridazole premix for preventing and treating poultry enterovirus syndrome |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103690940A true CN103690940A (en) | 2014-04-02 |
| CN103690940B CN103690940B (en) | 2015-07-01 |
Family
ID=50352708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310728696.5A Active CN103690940B (en) | 2013-12-26 | 2013-12-26 | Compound dimetridazole premix for preventing and treating poultry enterovirus syndrome |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103690940B (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108553423A (en) * | 2018-05-16 | 2018-09-21 | 厦门汇承科技有限公司 | Water-soluble Dimetridazole pre-mixing agent for animals of one kind and preparation method thereof |
| CN109329628A (en) * | 2018-12-05 | 2019-02-15 | 河北农业大学 | Pig feed additive and preparation method and application thereof |
| CN111632028A (en) * | 2020-06-17 | 2020-09-08 | 江西派尼生物药业有限公司 | High-stability dimetridazole premix |
| CN112998135A (en) * | 2021-03-25 | 2021-06-22 | 河南省健达动保有限公司 | High-efficiency compound mildew-removing and toxin-removing preparation |
| CN113425686A (en) * | 2021-07-29 | 2021-09-24 | 四川伴农动保生物技术有限公司 | Dimetridazole soluble powder and preparation method thereof |
| CN113813373A (en) * | 2021-11-15 | 2021-12-21 | 中国农业科学院兰州畜牧与兽药研究所 | Medicine for repairing intestinal mucosa and improving mucosal immunity and preparation method thereof |
| CN113813373B (en) * | 2021-11-15 | 2024-07-16 | 中国农业科学院兰州畜牧与兽药研究所 | Medicine for repairing intestinal mucosa and improving mucosal immune function and preparation method thereof |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101530405A (en) * | 2009-04-14 | 2009-09-16 | 何诚 | Citric acid and compound citric acid application in pharmacy |
| CN101579451A (en) * | 2009-07-07 | 2009-11-18 | 广东溢多利生物科技股份有限公司 | Chicken coccidia powder and preparation method thereof |
| CN102145011A (en) * | 2011-04-25 | 2011-08-10 | 广州华农大实验兽药有限公司 | Composition for preventing and curing diarrhea, preparation method and application of composition |
| CN102416169A (en) * | 2010-09-28 | 2012-04-18 | 瑞普（天津）生物药业有限公司 | Composition used for alimentary tract diseases of poultry |
| CN102600120A (en) * | 2012-01-04 | 2012-07-25 | 中国农业大学 | Application of cinnamic acid in preparation of drugs for preventing and treating livestock and poultry virus infection |
| CN102920719A (en) * | 2012-11-19 | 2013-02-13 | 菏泽普恩药业有限公司 | Compound veterinary medicine preparation for treating avian enteritis type colibacillosis |
| CN102988363A (en) * | 2012-11-19 | 2013-03-27 | 河南新正好生物工程有限公司 | Medicine for treating poultry proventriculitis and necrotic enteritis and preparation method thereof |
| CN103432162A (en) * | 2013-08-30 | 2013-12-11 | 天津生机集团股份有限公司 | Composition for treating poultry intestinal bacteria and anaerobic bacteria mixing infection and preparation method thereof |
-
2013
- 2013-12-26 CN CN201310728696.5A patent/CN103690940B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101530405A (en) * | 2009-04-14 | 2009-09-16 | 何诚 | Citric acid and compound citric acid application in pharmacy |
| CN101579451A (en) * | 2009-07-07 | 2009-11-18 | 广东溢多利生物科技股份有限公司 | Chicken coccidia powder and preparation method thereof |
| CN102416169A (en) * | 2010-09-28 | 2012-04-18 | 瑞普（天津）生物药业有限公司 | Composition used for alimentary tract diseases of poultry |
| CN102145011A (en) * | 2011-04-25 | 2011-08-10 | 广州华农大实验兽药有限公司 | Composition for preventing and curing diarrhea, preparation method and application of composition |
| CN102600120A (en) * | 2012-01-04 | 2012-07-25 | 中国农业大学 | Application of cinnamic acid in preparation of drugs for preventing and treating livestock and poultry virus infection |
| CN102920719A (en) * | 2012-11-19 | 2013-02-13 | 菏泽普恩药业有限公司 | Compound veterinary medicine preparation for treating avian enteritis type colibacillosis |
| CN102988363A (en) * | 2012-11-19 | 2013-03-27 | 河南新正好生物工程有限公司 | Medicine for treating poultry proventriculitis and necrotic enteritis and preparation method thereof |
| CN103432162A (en) * | 2013-08-30 | 2013-12-11 | 天津生机集团股份有限公司 | Composition for treating poultry intestinal bacteria and anaerobic bacteria mixing infection and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 宋培勇等: "鸡球虫病及其防治", 《养禽与禽病防治》 * |
| 杨德兴: "肉鸡球虫病的诊断与防治", 《畜牧兽医科技信息》 * |
| 王玉端等: "本地草鸡球虫病与线虫病混合感染的诊治", 《兽医导刊》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108553423A (en) * | 2018-05-16 | 2018-09-21 | 厦门汇承科技有限公司 | Water-soluble Dimetridazole pre-mixing agent for animals of one kind and preparation method thereof |
| CN109329628A (en) * | 2018-12-05 | 2019-02-15 | 河北农业大学 | Pig feed additive and preparation method and application thereof |
| CN111632028A (en) * | 2020-06-17 | 2020-09-08 | 江西派尼生物药业有限公司 | High-stability dimetridazole premix |
| CN112998135A (en) * | 2021-03-25 | 2021-06-22 | 河南省健达动保有限公司 | High-efficiency compound mildew-removing and toxin-removing preparation |
| CN113425686A (en) * | 2021-07-29 | 2021-09-24 | 四川伴农动保生物技术有限公司 | Dimetridazole soluble powder and preparation method thereof |
| CN113813373A (en) * | 2021-11-15 | 2021-12-21 | 中国农业科学院兰州畜牧与兽药研究所 | Medicine for repairing intestinal mucosa and improving mucosal immunity and preparation method thereof |
| CN113813373B (en) * | 2021-11-15 | 2024-07-16 | 中国农业科学院兰州畜牧与兽药研究所 | Medicine for repairing intestinal mucosa and improving mucosal immune function and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103690940B (en) | 2015-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103690940B (en) | Compound dimetridazole premix for preventing and treating poultry enterovirus syndrome | |
| ES2591041T3 (en) | Use of EDTA and its salts for the prevention and treatment of bacterial intestinal diseases in pigs | |
| CN102302599A (en) | Chinese medicinal composition for preventing and treating porcine diarrhea | |
| CN101934070A (en) | Veterinary antibacterial drug composition containing lysozyme and oligosaccharide and application thereof | |
| Hosseini et al. | Effects of xylanase supplementation and citric acid on performance, ileal nutrients digestibility, and gene expression of intestinal nutrient transporters in broilers challenged with Clostridium perfringens | |
| CN105287790A (en) | Paederia scandens extract and applications thereof | |
| CN102920771B (en) | Medicine for treating poultry coccidiosis | |
| CN107173584A (en) | A kind of feed addictive for treating swine fever | |
| BR112014020782B1 (en) | Process of improving feed efficiency and animal carcass characteristics | |
| Kyriakis et al. | Evaluation of Toyocerin, a probiotic containing Bacillus toyoi spores, on health status and productivity of weaned, growing and finishing pigs | |
| CN111450241A (en) | Composition for improving immunity of livestock | |
| CN113925894A (en) | Antibacterial and anti-inflammatory Chinese herbal medicine extract feed additive and application thereof | |
| CN103349699B (en) | Chinese herbal preparation capable of preventing and curing piglet's yellow-white dysentery and preparation method and application thereof | |
| CN101966200A (en) | Composition for treating poultry digestive tract bacterial infection and preparation method thereof | |
| CN101780266A (en) | Compound preparation for preventing and treating respiratory disease of livestock and poultry | |
| CN101757069A (en) | Oral medical liquid for treating chicken mixed infection as well as preparation method and application thereof | |
| Widjanarko et al. | Laxative potential of the konjac flour (Amorphophallus muelleri Blume) in treatment of loperamide induced constipation on Sprague Dawley rats | |
| CN104222652A (en) | Broiler chicken raising method | |
| CN103405490A (en) | Compound medicine for preventing and treating infectious diseases of livestock and poultry and preparation method thereof | |
| CN104288260B (en) | A kind of herbal medicine of effective preventing and treating porcine respiratory disease | |
| CN104189219B (en) | A kind of Chinese medicine composition | |
| CN107494922A (en) | It is a kind of to be used to adjust Tiny ecosystem Chinese herbal feed additive of enteron aisle and preparation method thereof | |
| CN101953879B (en) | Microbial ecological agent for quickly and efficiently preventing and treating pig high fever | |
| CN101313977B (en) | Intestine toxicity syndrome vaccine oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof | |
| CN105998321A (en) | Feed additive for treating and preventing broiler mycoplasmosis and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent of invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Liu Changdou Inventor after: Cao Sufang Inventor before: Liu Changdou |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: LIU CHANGDOU TO: LIU CHANGDOU CAO SUFANG |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |