CN103610797B - Traditional Chinese medicine composition for treating keratoconjunctivitis due to congestion and excess of dampness-heat - Google Patents
Traditional Chinese medicine composition for treating keratoconjunctivitis due to congestion and excess of dampness-heat Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating keratoconjunctivitis due to congestion and excess of dampness-heat. The traditional Chinese medicine composition is prepared from serissa serissoides, drymaria diandra, hemigraphis procumbens (Lour.) Merr., coptis root, Chinese taxillus herb, capsella bursa-pastoris, scorzonera subacaulis, paniculate swallowwort root and cape jasmine fruit. The traditional Chinese medicine composition can be clinically used for treating keratoconjunctivitis due to congestion and excess of dampness-heat.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of damp-heat retention keratoconjunctivitis.
Background technology
Keratoconjunctivitis is a kind of strong communicable contagious disease, is caused by adenovirus.Onset is anxious, severe symptoms, many eyes morbidities.Cardinal symptom has hyperemia, pain, photophobia with watery secretion.After morbidity a couple of days, there is disc of confusion point-like epithelial lesions in cornea.Often there is preauricular lymph nodes enlargement, and have tenderness.Doctor trained in Western medicine often uses intravenous injection cedilanid or verapamil, ethamine iodine barks ketone or oral quinidine is controlled, but side effect is very large, and can not effect a radical cure.Drug therapy damp-heat retention keratoconjunctivitis of the present invention reaches good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine composition to the treatment damp-heat retention keratoconjunctivitis of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizing the property of medicine of Chinese medicine uniqueness, adopting Radix Serissae, Herba drymariae cordatae, attached column flower, Rhizoma Coptidis, Herba Taxilli, Herba Capsellae, little Radix Scorzonerae austriacae, Radix Cynanchi Paniculati, Fructus Gardeniae according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention to be made up of following raw material medicaments: Radix Serissae 40-60 part, Herba drymariae cordatae 30-50 part, attached column flower 30-50 part, Rhizoma Coptidis 20-40 part, Herba Taxilli 20-40 part, Herba Capsellae 20-40 part, little Radix Scorzonerae austriacae 10-30 part, Radix Cynanchi Paniculati 10-30 part, Fructus Gardeniae 10-20 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: Radix Serissae 50 parts, Herba drymariae cordatae 40 parts, attached column spend 40 parts, Rhizoma Coptidis 30 parts, Herba Taxilli 30 parts, 30 parts, Herba Capsellae, little Radix Scorzonerae austriacae 20 parts, Radix Cynanchi Paniculati 20 parts, Fructus Gardeniae 15 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Serissae: bitter, pungent, cool, nontoxic.Return liver, spleen channel.Dispel the wind, dampness removing, heat clearing away, removing toxic substances.Clinical in flu, icterohepatitis, oedema due to nephritis, cough, laryngalgia, keratitis, enteritis, dysentery, lumbago and skelalgia, hemoptysis, hematuria, women's amenorrhea, leucorrhea, infantile malnutrition, infantile convulsion, acute toothache, the diseases such as traumatic injury.
Herba drymariae cordatae: bitter, cool.Return liver, stomach, urinary bladder channel.Clearing away heat-damp and promoting diuresis, promoting blood circulation and detoxication.Cure mainly jaundice, edema, malaria, infantile convulsion, rheumatism beriberi, the diseases such as corneal nebula.
Attached column flower: micro-hardship, pungent, cool.Heat-clearing and toxic substances removing, dampness removing is antipruritic, reducing swelling and alleviating pain.Clinical in dysentery, eczema, skin pruritus, the diseases such as traumatic injury.
Rhizoma Coptidis: bitter, cold.GUIXIN, liver, stomach, large intestine channel.Clearing away heat-fire, dampness, removing toxic substances.Cure mainly the high heat that calentura heresy enters heart channel, irritated, the damp and hot feeling of stuffiness in chest, rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain etc.
Herba Taxilli: bitter, sweet, flat.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive.For soreness of waist and knee joint, muscles and bones is thin and weak, rheumatic arthralgia, frequent fetal movement, metrostaxis.
Herba Capsellae: sweet, light, cool.Return liver, the heart, lung meridian.Cool liver hemostasis, suppressing the hyperactive liver improving eyesight, clearing away heat-damp and promoting diuresis.For spitting blood, hemoptysis, hematuria, metrorrhagia, conjunctival congestion and pain of eye, retinal hemorrhage, hypertension, the diseases such as oedema due to nephritis.
Little Radix Scorzonerae austriacae: sweet, bitter, cold in nature.Clearing away heat-damp and promoting diuresis, eliminating carbuncle, stimulating milk secretion.For damp-heat dysentery, urine leaching is puckery, carbuncle furunculosis, acute mastitis, agalactia etc.
Radix Cynanchi Paniculati: pungent, hot, returns spleen, stomach, kidney channel.Warming middle-JIAO to relieve pain, killing parasites for relieving itching, promoting blood circulation and detoxication, detumescence is used for gastropathy, and toothache, rheumatic arthralgia, lumbago, epigastric pain, cholecystitis, urine water conservancy, has loose bowels, dysentery, eczema, urticaria, venom.
Fructus Gardeniae: bitter, cold, GUIXIN, liver, lung, stomach warp.Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body., sore swollen toxin unhappy for calentura.
The traditional Chinese medical science thinks damp-heat retention keratoconjunctivitis for outer by ailment said due to cold or exposure, and priming liver-fire, wind heat is fought mutually, above attacks in order.In the present invention Radix Serissae dispel the wind, dampness removing, heat clearing away, removing toxic substances, for monarch drug, Herba drymariae cordatae clearing away heat-damp and promoting diuresis, promoting blood circulation and detoxication, attached column flower heat-clearing and toxic substances removing, dampness removing are antipruritic, are ministerial drug, Rhizoma Coptidis clearing away heat-fire, dampness, removing toxic substances, Herba Taxilli wind-damp dispelling, bone and muscle strengthening, the improving eyesight of Herba Capsellae suppressing the hyperactive liver, clearing away heat-damp and promoting diuresis, little Radix Scorzonerae austriacae clearing away heat-damp and promoting diuresis, Radix Cynanchi Paniculati is antipruritic, removing toxic substances, Fructus Gardeniae eliminating damp, detoxifying.Find through clinical practice, have unique curative effect to damp-heat retention keratoconjunctivitis, effect of heat-clearing and toxic substances removing, removing damp to relieve itching, promoting blood circulation by removing wind played altogether by all medicines, reaches the object for the treatment of damp-heat retention keratoconjunctivitis.
Chinese medicine composition of the present invention was in 2006 to 2010 the routine patients of clinical observation damp-heat retention keratoconjunctivitis 125, and clinical report is as follows:
1, physical data
In 125 routine patients, in age 17-43 year, the course of disease is many at 1 week to 4 months, 31 years old mean age.
2, diagnostic criteria
2.1 carry out clinical diagnosis with reference to the diagnosis basis in " Chinese medical disease Standardization of diagnosis and curative effect ":
Hyperemia of the bulbar conjunctiva, or see that subconjunctival ecchymosis is put in sheet, born of the same parents' eyelid is red and swollen, the visible punctate keratitis of black eyeball.Can lay one's hand on and core before ear or under chin.Eye is husky puckery, and causalgia, photophobia is shed tears, and notably hot tears are as soup, or a lot of secretion in the eye is rare clearly.
Damp-heat retention Corneal inflammation is shown in: suffer from eye and very itch unbearably, gritty is puckery sheds tears, and gum is thick, and in haircuts shape, born of the same parents' eyelid is heavy, cobble sample in eyelid, hyperemia of the bulbar conjunctiva, muddy colour, black and white eyeball intersection, swells in glue sample tuberosity, red tongue, yellow and greasy fur, rapid pulse.
3, Therapeutic Method
3.1 prescriptions: Radix Serissae 50g, Herba drymariae cordatae 40g, attached column flower 40g, Rhizoma Coptidis 30g, Herba Taxilli 30g, Herba Capsellae 30g, little Radix Scorzonerae austriacae 20g, Radix Cynanchi Paniculati 20g, Fructus Gardeniae 15g.
3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 5 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 treatment evaluation criterias, judge according to " the Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine formulates:
Cure: clinical symptoms and sign all disappear, vision restoration normal (or vision restoration is to premorbid vision);
Effective: vision improves, and clinical symptoms and sign all disappear;
Effective: clinical symptoms and sign all disappear or partial disappearance or improvement, and vision is without improve;
Invalid: vision without raising or clinical symptoms and sign without improvement or increase the weight of.
4.2 results: in 125 routine patients, cure 80 examples (64%), effective 32 examples (25.6%), effective 10 examples (8%), and invalid 3 examples (2.4%), total effective rate is 97.6%.
Model case
1, poplar, man, 33 years old, right eye was red red, and more than the photophobia pain recurrent exerbation moon, examine and see that right eye is red red, very itch unbearably, photophobia is shed tears, blurred vision, did, constipation when bitter taste, headache.Red tongue, thick, yellow and greasy fur, stringy pulse is number slightly.Check: hyperemia of the bulbar conjunctiva, black eyeball central authorities and periphery have the punctate opacity of the cornea of several Semen Sesami size.Vision: right eye 0.12, left eye 1.2, examines as damp-heat retention keratoconjunctivitis.Above-mentioned symptom after rear 2 courses for the treatment of of taking medicine alleviates, and eye is red redly slightly to go down, and checks that right vision is promoted to 0.8.Continue to take medicine of the present invention, after 1 course for the treatment of, transference cure, follows up a case by regular visits to after 1 year without recurrence.
2, high certain, female, 29 years old, eyes were red, bitterly, shed tears, existing with headache, heating.Check: binocular vision is 1.0, Dual-eyelid mild swelling, palpebral conjunctiva is obviously congested, and lower eyelid fornix portion has folliculus to be formed, and cornea of left eye has point-like inflammatory infiltration, red tongue, thick, yellow and greasy fur.Take 1 course for the treatment of of medicine of the present invention, every day 1 dose, transference cure, follow up a case by regular visits to after 1 year without recurrence.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, a kind of Chinese medicine composition for the treatment of damp-heat retention keratoconjunctivitis is made up of Radix Serissae 40g, Herba drymariae cordatae 30g, attached column flower 30g, Rhizoma Coptidis 20g, Herba Taxilli 20g, Herba Capsellae 20g, little Radix Scorzonerae austriacae 10g, Radix Cynanchi Paniculati 10g, Fructus Gardeniae 10g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of damp-heat retention keratoconjunctivitis is made up of Radix Serissae 50g, Herba drymariae cordatae 40g, attached column flower 40g, Rhizoma Coptidis 30g, Herba Taxilli 30g, Herba Capsellae 30g, little Radix Scorzonerae austriacae 20g, Radix Cynanchi Paniculati 20g, Fructus Gardeniae 15g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of damp-heat retention keratoconjunctivitis is made up of Radix Serissae 60g, Herba drymariae cordatae 50g, attached column flower 50g, Rhizoma Coptidis 40g, Herba Taxilli 40g, Herba Capsellae 40g, little Radix Scorzonerae austriacae 30g, Radix Cynanchi Paniculati 30g, Fructus Gardeniae 20g.
Claims (2)
1. treat a Chinese medicine composition for damp-heat retention keratoconjunctivitis, it is characterized in that it is made up of following raw material medicaments:
Radix Serissae 40-60 part, Herba drymariae cordatae 30-50 part, attached column flower 30-50 part, Rhizoma Coptidis 20-40 part, Herba Taxilli 20-40 part, Herba Capsellae 20-40 part, little Radix Scorzonerae austriacae 10-30 part, Radix Cynanchi Paniculati 10-30 part, Fructus Gardeniae 10-20 part.
2. Chinese medicine composition according to claim 1, is characterized in that it is made up of following raw material medicaments:
Radix Serissae 50 parts, Herba drymariae cordatae 40 parts, attached column spend 40 parts, Rhizoma Coptidis 30 parts, Herba Taxilli 30 parts, 30 parts, Herba Capsellae, little Radix Scorzonerae austriacae 20 parts, Radix Cynanchi Paniculati 20 parts, Fructus Gardeniae 15 parts.
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JP4933007B2 (en) * | 2001-09-21 | 2012-05-16 | ライオン株式会社 | Ophthalmic composition and method for enhancing antibacterial activity of the composition |
KR101165716B1 (en) * | 2010-06-15 | 2012-07-18 | 한국 한의학 연구원 | Compositions for prevention and treatment of allergic disease comprising the fractions from the extracts of Gardenia jasminoides as an active ingredient |
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CN1253797A (en) * | 1998-11-18 | 2000-05-24 | 陈江辉 | Chiyan yitiexiao plaster for curing acute contagious conjunctivitis and itspreparation method |
CN101164579A (en) * | 2007-09-20 | 2008-04-23 | 吴月 | Traditional Chinese medicine for curing keratitis |
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