CN103566165A - Process of exocarpium citri grandis tablets - Google Patents

Process of exocarpium citri grandis tablets Download PDF

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Publication number
CN103566165A
CN103566165A CN201210280452.0A CN201210280452A CN103566165A CN 103566165 A CN103566165 A CN 103566165A CN 201210280452 A CN201210280452 A CN 201210280452A CN 103566165 A CN103566165 A CN 103566165A
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CN
China
Prior art keywords
time
radix
hours
exocarpium citri
ethanol
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Pending
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CN201210280452.0A
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Chinese (zh)
Inventor
王建忠
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JIANDONG PHARMACEUTICAL INDUSTRY Co Ltd FUJIAN
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JIANDONG PHARMACEUTICAL INDUSTRY Co Ltd FUJIAN
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Priority to CN201210280452.0A priority Critical patent/CN103566165A/en
Publication of CN103566165A publication Critical patent/CN103566165A/en
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Abstract

The invention discloses a process of exocarpium citri grandis tablets. The process is characterized by comprising the following steps: preparing exocarpium citri grandis, pericarpium citri reticulatae, rhizoma pinellinae praeparata, poria cocos, liquorice, platycodon grandiflorum, semen armeniacae amarae, fried fructus perillae, radix asteris, flos farfarae, trichosanthes peels, thunberg fritillary bulb, rehmannia, radix ophiopogonis and gypsum; crushing the rhizoma pinellinae praeparata, the poria cocos, the thunberg fritillary bulb, the platycodon grandiflorum and the gypsum into fine powder; adding water into the fried fructus perillae, the liquorice, the radix asteris and the radix ophiopogonis and decocting for two times, wherein one time is lasted for three hours and one time is lasted for one hour; filtering decocting solutions of the two times and combining; adding water into the flos farfarae and hotly immersing for two times, wherein one time lasted for two hours and one time is lasted for one hour; filtering solutions obtained in the two times and combining; respectively heating and reflowing the trichosanthes peels and the rehmannia by using ethanol with the concentration of 48% and the semen armeniacae amarae by using ethanol with the concentration of 80% for two times, wherein one time lasts for three hours and one time lasts for one hour; filtering solutions obtained in the two times and combining; recycling the ethanol; distilling the exocarpium citri grandis and the pericarpium citri reticulatae and extracting volatile oil; filtering and extracting medicine liquid and combining with the medicine liquid; concentrating the medicine liquid into diluted cream with the relative density of 1.35-1.40 (at 60 DEG C); adding five types of fine powder including the rhizoma pinellinae praeparata and the like; and spraying the volatile oil and tabletting.

Description

A kind of technique of Exocarpium Citri Rubrum sheet
Technical field
The present invention relates to a kind of technique of Exocarpium Citri Rubrum sheet, belong to the improved technical field of production process of medical medicine.
Background technology
At present, the medicine that above market, treatment cough is reduced phlegm is innumerable, but, the comprehensive medicine really simultaneously with diseases such as treatment is reduced phlegm, cough, lung heat clearing is few, for the problems referred to above, the present inventor has proposed a kind of technique of Exocarpium Citri Rubrum sheet, and this medicine has the comprehensive medicine of the diseases such as treatment is reduced phlegm, cough, lung heat clearing simultaneously.
Summary of the invention
The technique that the object of this invention is to provide a kind of Exocarpium Citri Rubrum sheet, concrete technical scheme is as follows:
1, a technique for Exocarpium Citri Rubrum sheet, its material composition and content thereof are as follows:
Pericarpium Citri Reticulatae 116.3g
Rhizoma Pinelliae Preparatum 87.2g
Poria 116.3g
Radix Glycyrrhizae 58.1g
Radix Platycodonis 87.2g
Semen Armeniacae Amarum 116.3g
Fructus Perillae (parched) 87.2g
Radix Asteris 87.2g
Flos Farfarae 58.1g
Pericarpium Trichosanthis 116.3g
Bulbus Fritillariae Thunbergii 116.3g
Radix Rehmanniae 116.3g
Radix Ophiopogonis 116.3g
Gypsum Fibrosum 116.3g.
2, processing technology: by above Rhizoma Pinelliae Preparatum, Poria, Bulbus Fritillariae Thunbergii, Radix Platycodonis and Gypsum Fibrosum powder are broken into fine powder, by Fructus Perillae (parched), Radix Glycyrrhizae, decoct with water Radix Asteris and Radix Ophiopogonis secondary, three hours for the first time, one hour for the second time, filter, the decocting liquid of twice is merged, Flos Farfarae adds hydro-thermal and soaks secondary, two hours for the first time, one hour for the second time, filter, the filtrate of twice is merged, Pericarpium Trichosanthis, Radix Rehmanniae 48% ethanol, Semen Armeniacae Amarum 80% ethanol, reflux is twice respectively, three hours for the first time, two hours for the second time, filter, the filtrate of twice is merged, reclaim ethanol, Exocarpium Citri Grandis and Pericarpium Citri Reticulatae distillating extracting oil are most to oil, and filter and extract medicinal liquid, merge with above-mentioned medicinal liquid, being evaporated to relative density is 1.35-1.40(60 ℃) clear paste, the five tastes fine powders such as the addition method Rhizoma Pinelliae are mixed, dry, be ground into fine powder, with alcohol granulation, dry, spray adds the volatile oil of Exocarpium Citri Grandis and Pericarpium Citri Reticulatae, be mixed, be pressed into 1000.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, patent of the present invention is described further:
Fig. 1 is patent process flow diagram of the present invention;
The specific embodiment
The composition of raw materials providing by foregoing invention technical scheme, by above Rhizoma Pinelliae Preparatum, Poria, Bulbus Fritillariae Thunbergii, Radix Platycodonis and Gypsum Fibrosum powder are broken into fine powder, by Fructus Perillae (parched), Radix Glycyrrhizae, decoct with water Radix Asteris and Radix Ophiopogonis secondary, three hours for the first time, one hour for the second time, filter, the decocting liquid of twice is merged, Flos Farfarae adds hydro-thermal and soaks secondary, two hours for the first time, one hour for the second time, filter, the filtrate of twice is merged, Pericarpium Trichosanthis, Radix Rehmanniae 48% ethanol, Semen Armeniacae Amarum 80% ethanol, reflux is twice respectively, three hours for the first time, two hours for the second time, filter, the filtrate of twice is merged, reclaim ethanol, Exocarpium Citri Grandis and Pericarpium Citri Reticulatae distillating extracting oil are most to oil, and filter and extract medicinal liquid, merge with above-mentioned medicinal liquid, being evaporated to relative density is 1.35-1.40(60 ℃) clear paste, the five tastes fine powders such as the addition method Rhizoma Pinelliae are mixed, dry, be ground into fine powder, with alcohol granulation, dry, spray adds the volatile oil of Exocarpium Citri Grandis and Pericarpium Citri Reticulatae, be mixed, be pressed into 1000.

Claims (2)

1. a technique for Exocarpium Citri Rubrum sheet, is characterized in that: this material composition and content thereof are as follows:
Pericarpium Citri Reticulatae 116.3g
Rhizoma Pinelliae Preparatum 87.2g
Poria 116.3g
Radix Glycyrrhizae 58.1g
Radix Platycodonis 87.2g
Semen Armeniacae Amarum 116.3g
Fructus Perillae (parched) 87.2g
Radix Asteris 87.2g
Flos Farfarae 58.1g
Pericarpium Trichosanthis 116.3g
Bulbus Fritillariae Thunbergii 116.3g
Radix Rehmanniae 116.3g
Radix Ophiopogonis 116.3g
Gypsum Fibrosum 116.3g.
2. the technique of a kind of Exocarpium Citri Rubrum sheet according to claim 1, by above Rhizoma Pinelliae Preparatum, Poria, Bulbus Fritillariae Thunbergii, Radix Platycodonis and Gypsum Fibrosum powder are broken into fine powder, by Fructus Perillae (parched), Radix Glycyrrhizae, decoct with water Radix Asteris and Radix Ophiopogonis secondary, three hours for the first time, one hour for the second time, filter, the decocting liquid of twice is merged, Flos Farfarae adds hydro-thermal and soaks secondary, two hours for the first time, one hour for the second time, filter, the filtrate of twice is merged, Pericarpium Trichosanthis, Radix Rehmanniae 48% ethanol, Semen Armeniacae Amarum 80% ethanol, reflux is twice respectively, three hours for the first time, two hours for the second time, filter, the filtrate of twice is merged, reclaim ethanol, Exocarpium Citri Grandis and Pericarpium Citri Reticulatae distillating extracting oil are most to oil, and filter and extract medicinal liquid, merge with above-mentioned medicinal liquid, being evaporated to relative density is 1.35-1.40(60 ℃) clear paste, the five tastes fine powders such as the addition method Rhizoma Pinelliae are mixed, dry, be ground into fine powder, with alcohol granulation, dry, spray adds the volatile oil of Exocarpium Citri Grandis and Pericarpium Citri Reticulatae, be mixed, be pressed into 1000.
CN201210280452.0A 2012-08-09 2012-08-09 Process of exocarpium citri grandis tablets Pending CN103566165A (en)

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CN201210280452.0A CN103566165A (en) 2012-08-09 2012-08-09 Process of exocarpium citri grandis tablets

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104225558A (en) * 2014-09-29 2014-12-24 栗明峰 Quick-acting external use patch for pneumonia and preparation method thereof
CN105232936A (en) * 2015-10-25 2016-01-13 四川双鑫生物科技有限公司 Decoction medicine capable of treating cold, cough and phlegm and preparation method thereof
CN105343469A (en) * 2014-12-26 2016-02-24 杭州美誉医药有限公司 Traditional Chinese medicine preparation for treating cough and preparation method and uses
CN108714171A (en) * 2018-06-09 2018-10-30 广东永青生物科技有限公司 Strengthening flesh by the strong bone that fructose and Exocarpium Citri Rubrum form for one group enhances the health food of locomitivity and the formula and processing technology of drug

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011527A (en) * 2007-02-01 2007-08-08 四川美大康药业股份有限公司 Improved preparation of Juhong pill, its preparation method and quality inspection method
KR20110124442A (en) * 2010-05-11 2011-11-17 송시훈 Composition for improving physiological activity of positive constitution

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011527A (en) * 2007-02-01 2007-08-08 四川美大康药业股份有限公司 Improved preparation of Juhong pill, its preparation method and quality inspection method
KR20110124442A (en) * 2010-05-11 2011-11-17 송시훈 Composition for improving physiological activity of positive constitution

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吕武清等: "《中成药中的药材薄层色谱鉴别》", 31 March 1997, 人民卫生出版社 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104225558A (en) * 2014-09-29 2014-12-24 栗明峰 Quick-acting external use patch for pneumonia and preparation method thereof
CN104225558B (en) * 2014-09-29 2018-06-05 栗明峰 A kind of pneumonia external patch and preparation method thereof
CN105343469A (en) * 2014-12-26 2016-02-24 杭州美誉医药有限公司 Traditional Chinese medicine preparation for treating cough and preparation method and uses
CN105232936A (en) * 2015-10-25 2016-01-13 四川双鑫生物科技有限公司 Decoction medicine capable of treating cold, cough and phlegm and preparation method thereof
CN108714171A (en) * 2018-06-09 2018-10-30 广东永青生物科技有限公司 Strengthening flesh by the strong bone that fructose and Exocarpium Citri Rubrum form for one group enhances the health food of locomitivity and the formula and processing technology of drug

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Application publication date: 20140212