CN1593603A - Emmeniopathy treating Chinese medicinal capsule and its preparation - Google Patents

Emmeniopathy treating Chinese medicinal capsule and its preparation Download PDF

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Publication number
CN1593603A
CN1593603A CN 200410045007 CN200410045007A CN1593603A CN 1593603 A CN1593603 A CN 1593603A CN 200410045007 CN200410045007 CN 200410045007 CN 200410045007 A CN200410045007 A CN 200410045007A CN 1593603 A CN1593603 A CN 1593603A
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China
Prior art keywords
radix
rhizoma
radix paeoniae
angelicae sinensis
atractylodis macrocephalae
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CN 200410045007
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Chinese (zh)
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谢子龙
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Individual
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Individual
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Priority to CN 200410045007 priority Critical patent/CN1593603A/en
Publication of CN1593603A publication Critical patent/CN1593603A/en
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention provides a Chinese medicinal preparation for treating abnormal menstruation, whose main compositions include nutagrass flatsedge rhizome, Ligusticum wallichii, Chinese angelica root, corydalis tuber, white atractylodes rhizome, licorice root, root of herbaceous peony, radix paeoniae rubrathe, red date, prepared rehmannia root, and calcium carbonate. Its preparing process is also disclosed in the invention.

Description

Gynecological's ten flavor capsules and preparation method thereof
Technical field:
The present invention relates to a kind of Chinese medicinal capsule agent and process for making thereof, relate in particular to gynecological's ten flavor capsules and preparation method thereof.
Background technology:
Capsule is a kind of pharmaceutical dosage form commonly used, according to the relevant laws and regulations of China's drug control, changes dosage form and manages as new drug research.The original dosage form of this product is a tablet, has listed the national drug ministry standard in.
The technology features of former dosage form be with the prescription Chinese crude drug pulverize, extract, concentrate, dry, pulverize, add adjuvant and granulate, tabletting, coating, promptly.
There is difficult disintegrate in existing tablet of ten ingredients for woman diseases, and onset is slow, the drawback of medicine stability difference.
Summary of the invention:
The purpose of this invention is to provide the rapid disintegrate onset of a kind of energy.Be used for the treatment of hepatic depression and blood deficiency, menoxenia, menalgia, Chinese medicinal capsule preparation of amenorrhea etc. cards and preparation method thereof overcomes the above-mentioned drawback of prior art, improves the quality and the curative effect of product, satisfies the needs of medical treatment better.
Technical solution of the present invention is a kind of gynecological ten flavor capsules, it is a kind of treatment menoxenia, the Chinese patent medicine of card such as menalgia, it is that main constituent is the capsule of Rhizoma Cyperi, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Rhizoma Corydalis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Fructus Jujubae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Radix Rehmanniae Preparata, calcium carbonate.
The capsular preparation method of a kind of gynecological's ten flavors is characterized in that:
(1) getting main medicine constituent and percentage by weight thereof is:
Rhizoma Cyperi 24~72%, Rhizoma Chuanxiong 1~3%, Radix Angelicae Sinensis 9~26%, Rhizoma Corydalis 2~6%, the Rhizoma Atractylodis Macrocephalae 1~4%, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Paeoniae Rubra each 1~2%, Fructus Jujubae 5~15%, Radix Rehmanniae Preparata, calcium carbonate each 3~9%;
(2) in the above-mentioned flavour of a drug, get 70% Radix Angelicae Sinensis, Rhizoma Cyperi, Rhizoma Corydalis, the Radix Paeoniae Alba, Radix Paeoniae Rubra, that Paris white is broken into fine powder is standby;
(3) get above-mentioned Radix Glycyrrhizae, Fructus Jujubae decocts with water three times, filters merging filtrate;
(4) get above-mentioned all the other Radix Angelicae Sinensis of 30%, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong with 70% alcohol heating reflux extraction secondary, filter, merging filtrate reclaims ethanol.
(5) two kinds of filtrates of above (3), (4) gained merge, and are evaporated to the thick paste of relative density 1.35~1.40 (50 ℃).
(6) by the quantitative thick paste mixing of Six-element fine powder such as the Rhizoma Cyperi that quantitatively adds above-mentioned (2) gained with above-mentioned (5) gained, drying is ground into fine powder, adds the granulation of the amount of making adjuvant, drying, and fill becomes capsule.
(7) used adjuvant can be in the preparation: any/multiple mixing during micropowder silica gel, starch, dextrin, magnesium stearate, essence, Pulvis Talci, sucrose, microcrystalline Cellulose, carboxymethyl starch are received is used.
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of gynecological ten flavor capsules are a kind of treatment hepatic depression and blood deficiencies, menoxenia, and menalgia, the Chinese patent medicine of card such as amenorrhea, its main constituent is Rhizoma Cyperi, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Rhizoma Corydalis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Fructus Jujubae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Radix Rehmanniae Preparata, calcium carbonate.
The optimum implementation of a kind of gynecological ten flavor capsule preparation method thereofs is:
(1) getting main medicine constituent and optimum weight percentage ratio thereof is: Rhizoma Cyperi 48.2%, Rhizoma Chuanxiong 1.9%, Radix Angelicae Sinensis 17.4%, Rhizoma Corydalis 3.9%, the Rhizoma Atractylodis Macrocephalae 2.8%, Radix Glycyrrhizae 1.3%, Fructus Jujubae 9.6%, the Radix Paeoniae Alba, Radix Paeoniae Rubra each 1.4%, Radix Rehmanniae Preparata 5.8%, calcium carbonate 6.3%;
(2) in the above flavour of a drug, get 70% Radix Angelicae Sinensis, Rhizoma Cyperi, Rhizoma Corydalis, the Radix Paeoniae Alba, Radix Paeoniae Rubra, that Paris white is broken into fine powder is standby; Extracting liquorice, Fructus Jujubae decoct with water three times, filter merging filtrate; Get all the other Radix Angelicae Sinensis of 30%, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong with 70% alcohol heating reflux extraction secondary, filter, merging filtrate reclaims ethanol.Two kinds of filtrates of above gained are merged, be evaporated to the thick paste of relative density 1.35~1.40 (50 ℃).By the quantitative thick paste mixing of Six-element fine powder such as the Rhizoma Cyperi that quantitatively adds above-mentioned gained with above-mentioned gained, drying is ground into fine powder, adds the granulation of the amount of making adjuvant, drying, and fill becomes capsule.
Advantage of the present invention is: get final product rapid disintegration after gynaecology's ten flavor capsules are taken, rapid-action, medicine stability is good, Be beneficial to storage, produce, carry and improve the product curative effect, can satisfy better the treatment needs.

Claims (3)

1, a kind of gynecological ten flavor capsules, it is a kind of treatment hepatic depression and blood deficiency, menoxenia, menalgia, the Chinese patent medicine of card such as amenorrhea is characterized in that it is that main constituent is the capsule of Rhizoma Cyperi, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Rhizoma Corydalis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Fructus Jujubae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Radix Rehmanniae Preparata, calcium carbonate.
2, the capsular preparation method of a kind of gynecological's ten flavors is characterized in that:
(1) getting main medicine constituent and percentage by weight thereof is:
Rhizoma Cyperi 24~72%, Rhizoma Chuanxiong 1~3%, Radix Angelicae Sinensis 9~26%, Rhizoma Corydalis 2~6%, the Rhizoma Atractylodis Macrocephalae 1~4%, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Paeoniae Rubra each 1~2%, Fructus Jujubae 5~15%, Radix Rehmanniae Preparata, calcium carbonate each 3~9%;
(2) in the above flavour of a drug, get 70% Radix Angelicae Sinensis, Rhizoma Cyperi, Rhizoma Corydalis, the Radix Paeoniae Alba, Radix Paeoniae Rubra, that Paris white is broken into fine powder is standby;
(3) extracting liquorice, Fructus Jujubae decoct with water three times, filter merging filtrate;
(4) get all the other Radix Angelicae Sinensis of 30%, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Rhizoma Chuanxiong with 70% alcohol heating reflux extraction secondary, filter, merging filtrate reclaims ethanol.
(5) two kinds of filtrates with above (3) (4) gained merge, and are evaporated to the thick paste of relative density 1.35~1.40 (50 ℃).
(6) by the quantitative thick paste mixing of Six-element fine powder such as the Rhizoma Cyperi that quantitatively adds above-mentioned (2) gained with above-mentioned (5) gained, drying is ground into fine powder, adds the appropriate amount of auxiliary materials granulation, drying, and fill becomes capsule.
3, the capsular preparation method of gynecological's ten flavors according to claim 2, the optimum weight percentage ratio that it is characterized in that its main constituent is: Rhizoma Cyperi 48.2%, Rhizoma Chuanxiong 1.9%, Radix Angelicae Sinensis 17.4%, Rhizoma Corydalis 3.9%, the Rhizoma Atractylodis Macrocephalae 2.8%, Radix Glycyrrhizae 1.3%, Fructus Jujubae 9.6%, the Radix Paeoniae Alba, Radix Paeoniae Rubra each 1.4%, Radix Rehmanniae Preparata 5.8%, calcium carbonate 6.3%.
CN 200410045007 2004-07-08 2004-07-08 Emmeniopathy treating Chinese medicinal capsule and its preparation Pending CN1593603A (en)

Priority Applications (1)

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CN 200410045007 CN1593603A (en) 2004-07-08 2004-07-08 Emmeniopathy treating Chinese medicinal capsule and its preparation

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CN1593603A true CN1593603A (en) 2005-03-16

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102008621A (en) * 2010-12-09 2011-04-13 张月英 Traditional Chinese medicine pill for curing amenorrhea resulted from psychotropic drugs and preparation method thereof
CN102106949A (en) * 2009-12-25 2011-06-29 华斯农业开发股份有限公司 Mink feed traditional Chinese medicine
CN103316179A (en) * 2013-05-20 2013-09-25 回音必集团安徽制药有限公司 Preparation method of Fuke Shiwei tablets
CN111110807A (en) * 2018-10-16 2020-05-08 党广旺 Pharmaceutical composition with analgesic function
CN113893224A (en) * 2020-06-22 2022-01-07 九芝堂股份有限公司 Preparation method of gynecological ten-ingredient tablet

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106949A (en) * 2009-12-25 2011-06-29 华斯农业开发股份有限公司 Mink feed traditional Chinese medicine
CN102008621A (en) * 2010-12-09 2011-04-13 张月英 Traditional Chinese medicine pill for curing amenorrhea resulted from psychotropic drugs and preparation method thereof
CN102008621B (en) * 2010-12-09 2011-12-07 张月英 Traditional Chinese medicine pill for curing amenorrhea resulted from psychotropic drugs and preparation method thereof
CN103316179A (en) * 2013-05-20 2013-09-25 回音必集团安徽制药有限公司 Preparation method of Fuke Shiwei tablets
CN111110807A (en) * 2018-10-16 2020-05-08 党广旺 Pharmaceutical composition with analgesic function
CN113893224A (en) * 2020-06-22 2022-01-07 九芝堂股份有限公司 Preparation method of gynecological ten-ingredient tablet

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