CN103558397A - 一种缺血修饰白蛋白检测试剂及检测方法 - Google Patents
一种缺血修饰白蛋白检测试剂及检测方法 Download PDFInfo
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- CN103558397A CN103558397A CN201310537922.1A CN201310537922A CN103558397A CN 103558397 A CN103558397 A CN 103558397A CN 201310537922 A CN201310537922 A CN 201310537922A CN 103558397 A CN103558397 A CN 103558397A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6827—Total protein determination, e.g. albumin in urine
- G01N33/683—Total protein determination, e.g. albumin in urine involving metal ions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/775—Indicator and selective membrane
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
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CN201310537922.1A CN103558397B (zh) | 2013-11-04 | 2013-11-04 | 一种缺血修饰白蛋白检测试剂及检测方法 |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105021609A (zh) * | 2015-07-06 | 2015-11-04 | 广州金域医学检验中心有限公司 | 一种缺血修饰白蛋白检测试剂及其检测方法 |
CN106093017A (zh) * | 2016-04-28 | 2016-11-09 | 安徽伊普诺康生物技术股份有限公司 | 一种测定缺血修饰白蛋白的试剂盒及其制备方法 |
CN111366715A (zh) * | 2018-12-25 | 2020-07-03 | 深圳迈瑞生物医疗电子股份有限公司 | 抗肝素干扰剂及抗肝素干扰的试剂盒 |
CN112763731A (zh) * | 2020-12-29 | 2021-05-07 | 广州市伊川生物科技有限公司 | 一种脂蛋白(a)测定试剂盒及其检测方法 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101013137A (zh) * | 2007-02-06 | 2007-08-08 | 贺坚慧 | 一类检测缺血性修饰白蛋白的试剂盒及其检测方法 |
WO2007093902A1 (en) * | 2006-02-15 | 2007-08-23 | Inverness Medical Switzerland Gmbh | Assays |
CN101458257A (zh) * | 2007-12-12 | 2009-06-17 | 上海复星医药(集团)股份有限公司 | 检测缺血修饰白蛋白的试剂盒及其制备方法 |
CN101655500A (zh) * | 2009-09-08 | 2010-02-24 | 贺坚慧 | 一种红光检测缺血修饰白蛋白的试剂盒及其检测方法 |
WO2011022628A1 (en) * | 2009-08-20 | 2011-02-24 | The Board Of Regents Of The University Of Texas System | Methods and compositions for diagnosis of acute myocardial infarction (ami) |
CN102147416A (zh) * | 2011-01-19 | 2011-08-10 | 四川省新成生物科技有限责任公司 | 稳定的缺血修饰白蛋白测定试剂盒 |
CN102507916A (zh) * | 2011-11-07 | 2012-06-20 | 宁波美康生物科技股份有限公司 | 缺血修饰白蛋白液体稳定试剂盒 |
CN103344768A (zh) * | 2013-07-10 | 2013-10-09 | 中国人民解放军第三军医大学第一附属医院 | 缺血性心脏病检测试剂盒及其应用 |
-
2013
- 2013-11-04 CN CN201310537922.1A patent/CN103558397B/zh active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007093902A1 (en) * | 2006-02-15 | 2007-08-23 | Inverness Medical Switzerland Gmbh | Assays |
CN101013137A (zh) * | 2007-02-06 | 2007-08-08 | 贺坚慧 | 一类检测缺血性修饰白蛋白的试剂盒及其检测方法 |
CN101458257A (zh) * | 2007-12-12 | 2009-06-17 | 上海复星医药(集团)股份有限公司 | 检测缺血修饰白蛋白的试剂盒及其制备方法 |
WO2011022628A1 (en) * | 2009-08-20 | 2011-02-24 | The Board Of Regents Of The University Of Texas System | Methods and compositions for diagnosis of acute myocardial infarction (ami) |
CN101655500A (zh) * | 2009-09-08 | 2010-02-24 | 贺坚慧 | 一种红光检测缺血修饰白蛋白的试剂盒及其检测方法 |
CN102147416A (zh) * | 2011-01-19 | 2011-08-10 | 四川省新成生物科技有限责任公司 | 稳定的缺血修饰白蛋白测定试剂盒 |
CN102507916A (zh) * | 2011-11-07 | 2012-06-20 | 宁波美康生物科技股份有限公司 | 缺血修饰白蛋白液体稳定试剂盒 |
CN103344768A (zh) * | 2013-07-10 | 2013-10-09 | 中国人民解放军第三军医大学第一附属医院 | 缺血性心脏病检测试剂盒及其应用 |
Non-Patent Citations (1)
Title |
---|
包丽华等: "新显色剂噻二唑偶氮二甲氨基苯酚与钴显色反应研究和应用", 《山东农业大学学报(自然科学版)》 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105021609A (zh) * | 2015-07-06 | 2015-11-04 | 广州金域医学检验中心有限公司 | 一种缺血修饰白蛋白检测试剂及其检测方法 |
CN106093017A (zh) * | 2016-04-28 | 2016-11-09 | 安徽伊普诺康生物技术股份有限公司 | 一种测定缺血修饰白蛋白的试剂盒及其制备方法 |
CN111366715A (zh) * | 2018-12-25 | 2020-07-03 | 深圳迈瑞生物医疗电子股份有限公司 | 抗肝素干扰剂及抗肝素干扰的试剂盒 |
CN111366715B (zh) * | 2018-12-25 | 2024-04-12 | 深圳迈瑞生物医疗电子股份有限公司 | 抗肝素干扰剂及抗肝素干扰的试剂盒 |
CN112763731A (zh) * | 2020-12-29 | 2021-05-07 | 广州市伊川生物科技有限公司 | 一种脂蛋白(a)测定试剂盒及其检测方法 |
CN112763731B (zh) * | 2020-12-29 | 2023-02-28 | 广州市伊川生物科技有限公司 | 一种脂蛋白(a)测定试剂盒及其检测方法 |
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Denomination of invention: A detection reagent and method for ischemic modified albumin Effective date of registration: 20230601 Granted publication date: 20150610 Pledgee: Overpass Branch of Jinan Rural Commercial Bank Co.,Ltd. Pledgor: BIOBASE BIODUSTRY (SHANDONG) Co.,Ltd. Registration number: Y2023980042636 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right |
Granted publication date: 20150610 Pledgee: Overpass Branch of Jinan Rural Commercial Bank Co.,Ltd. Pledgor: BIOBASE BIODUSTRY (SHANDONG) Co.,Ltd. Registration number: Y2023980042636 |