CN103468568B - Filtration unit, filter member and filter method - Google Patents
Filtration unit, filter member and filter method Download PDFInfo
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- CN103468568B CN103468568B CN201310421896.6A CN201310421896A CN103468568B CN 103468568 B CN103468568 B CN 103468568B CN 201310421896 A CN201310421896 A CN 201310421896A CN 103468568 B CN103468568 B CN 103468568B
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- inner tray
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Abstract
The invention discloses filtration unit, filter member and filter method, this filtration unit comprises and holds sample section, leads sample section and filter member, the connection leading sample section is provided with at least two longitudinal slots, described filter member has inner tray, outer disk body, filtering membrane and at least two cross structures, inner tray to be positioned in the middle part of outer disk body and to be connected by cross structure, inner tray is provided with filter pore, filter pore place is located at by filtering membrane, cross structure is positioned at longitudinal slot, holds sample section and the coupling end of leading sample section and is connected by coupling device and is communicated by filtering membrane.Filtering membrane can take out by the present invention easily, effectively decreases the pollution to sample.
Description
Technical field
The invention belongs to medical instruments field, be specifically related to filtration unit, filter member and filter method.
Background technology
Some specific blood cells, such as tumour cell, the ratio existed is very little, but compared with other cell existed in blood, their volume is comparatively large, therefore, when utilizing some instrument to detect, in order to ensure the accuracy detected, need to filter cell to be detected, general cell filtration method is that blood sample is passed through filtration devices.
In clinical medicine, also may filter other samples, to detect.
But now filtration unit sold on the market mostly is simple strainer, and its shortcoming is: single filtration volume is little, it is extremely inconvenient to use, lose time and manpower; There is again a kind of cell filtering device afterwards, and just still there is filtering membrane and take out inconvenient defect, in some cases even can contaminated sample.
Summary of the invention
Based on this, the invention reside in the defect overcoming prior art, provide a kind of filtration unit, filter member and filter method, filtering membrane can take out by the present invention easily, effectively decreases the pollution to sample.
Its technical scheme is as follows:
Filtration unit, comprise and hold sample section, lead sample section and filter member, the coupling end of leading sample section is provided with at least two longitudinal slots, described filter member has inner tray, outer disk body, filtering membrane and at least two cross structures, inner tray to be positioned in the middle part of outer disk body and to be connected by cross structure, and inner tray is provided with filter pore, and filter pore place is located at by filtering membrane, cross structure is positioned at longitudinal slot, holds sample section and the coupling end of leading sample section and is connected by coupling device and is communicated by filtering membrane.
Below further technical scheme is described:
The bottom of described longitudinal slot has the first translot of at least two circumferential direction.
The middle part of described longitudinal slot has the second translot of at least two circumferential direction, at the coupling end of described appearance sample section, there are at least two clamping projections, the quantity of clamping projection is identical with the quantity of the second translot and position relative, and described coupling device is that this second translot and clamping are protruding.
Described first translot, the second translot are identical relative to the direction of described longitudinal slot.
Described coupling end of leading sample section has clamping outer wall and interior land, and interior land is positioned at clamping outer wall, and the end face holding the coupling end of sample section is relative with interior land and inner tray compressed.
Described coupling end of leading sample section also has outward flange, and the diameter of outward flange is greater than the diameter of clamping outer wall, and described outer disk body is positioned at the top of described outward flange.
Described outward flange is provided with two steps down scarce, two opposition sides lacking and lay respectively at outward flange of stepping down.
The end face of coupling end holding sample section and interior land are equipped with wear ring, two wear rings respectively from both sides by two side compressions of inner tray.
The invention also discloses a kind of filter member, have inner tray, outer disk body, filtering membrane and at least two cross structures, inner tray to be positioned in the middle part of outer disk body and to be connected by cross structure, and inner tray is provided with filter pore, and filter pore place is located at by filtering membrane.
The invention also discloses a kind of filter method, it comprises the steps:
Hold the outer disk body of filter member, by cross structure inner tray is placed in the coupling end of leading sample section, appearance sample section is connected with the coupling end of leading sample section; Take off after sample is filtered and hold sample section; Hold the outer disk body of filter member, and by cross structure, inner tray is taken out.
Below the principle, effect etc. of preceding solution are described:
1, because this filter member has inner tray, outer disk body and cross structure, when putting into or take out filtering membrane, outer disk body can be held and operate, putting into or take out more convenient; And realize inner tray (and filtering membrane) to put into or take out by the outer disk body of operation, avoid direct contacted filter membrane or sample is polluted.
2, the bottom of described longitudinal slot has the first translot of circumference, after cross structure is placed in longitudinal slot, can rotates outer disk body again and cross structure is stuck in the first translot, avoid filter member arbitrarily deviate from and pollute, and improves operability and reliability further.
3, the middle part of described longitudinal slot has the second translot of circumferential direction, clamping projection is stuck in longitudinal slot and rotates the connection that can realize leading sample section and holding sample section along the second translot, can realize leading sample section and holding disassembling of sample section along the second translot reverse rotation by protruding for clamping, easy to use.
4, described first translot, the second translot are identical relative to the direction of described longitudinal slot, and when clamping projection screws in, the cross structure of filter member can be taken advantage of a situation and be snapped in the first translot, uses more convenient.
The coupling end of leading sample section 5, has clamping outer wall and interior land, longitudinal slot on clamping outer wall can with clamping male cooperation and realize holding sample section and the connection of leading sample section, inner tray compresses by the end face holding the coupling end of sample section together with interior land, avoids sample leakage.
The coupling end of leading sample section 6, also has outward flange, and this outward flange can provide support for outer disk body or protect.
7, be provided with on described outward flange step down scarce, by this step down lack can easily externally disk body grip.
Accompanying drawing explanation
Fig. 1 is the structure iron of filtration unit described in the embodiment of the present invention;
Fig. 2 is the disassembly diagram of Fig. 1;
Fig. 3 is the structure iron of filter member;
Fig. 4 is the oblique drawing of leading sample section;
Fig. 5 is the side-view of leading sample section;
Fig. 6 is the use schematic flow sheet of filtration unit described in the embodiment of the present invention;
Description of reference numerals:
10, sample section is held, 11, injection port, 12, clamping is protruding, 20, sample section is led, 21, clamping outer wall, 211, longitudinal slot, 212, the first translot, the 213, second translot, 22, interior land, 23, outward flange, 231, step down scarce, 24, lead sample mouth, 30, filter member, 31, outer disk body, 32, inner tray, 33, cross structure, 34, filtering membrane, 40, wear ring.
Embodiment
Below embodiments of the invention are described in detail:
As shown in Figures 1 to 5, filtration unit, comprise and hold sample section 10, lead sample section 20 and filter member 30, the coupling end of leading sample section 20 is provided with at least two longitudinal slots 211, described filter member 30 has inner tray 32, outer disk body 31, filtering membrane 34 and two cross structures 33, inner tray 32 to be positioned in the middle part of outer disk body 31 and to be connected by cross structure 33, inner tray 32 is provided with filter pore, filter pore place is located at by filtering membrane 34, cross structure 33 is positioned at longitudinal slot 211, holds sample section 10 and the coupling end of leading sample section 20 and is connected by coupling device and is communicated by filtering membrane 34.
Wherein, the bottom of described longitudinal slot 211 has the first translot 212 of two circumferential direction, the middle part of described longitudinal slot 211 has the second translot 213 of two circumferential direction, described first translot 212, second translot 213 is identical relative to the direction of described longitudinal slot 211, at the coupling end of described appearance sample section 10, there are two clamping projections 12, the quantity of clamping projection 12 is identical with the quantity of the second translot 213 and position relative, and described coupling device is this second translot 213 and clamping projection 12.
Described coupling end of leading sample section 20 has clamping outer wall 21 and interior land 22, interior land 22 is positioned at clamping outer wall 21, the end face holding the coupling end of sample section 10 is relative with interior land 22 and inner tray 32 compressed, for enhanced leaktightness effect, the end face of coupling end holding sample section 10 and interior land 22 are equipped with wear ring 40, two wear rings 40 respectively from both sides by two side compressions of inner tray 32.Described coupling end of leading sample section 20 also has outward flange 23, and the diameter of outward flange 23 is greater than the diameter of clamping outer wall 21, and described outer disk body 31 is positioned at the top of described outward flange 23.Described outward flange 23 is provided with two and steps down scarce 231, two scarce 231 opposition sides laying respectively at outward flange 23 of stepping down.
The use flow process of this filtration unit as shown in Figure 6, hold the outer disk body 31 of filter member 30, by cross structure 33 inner tray 32 is placed in (now cross structure 33 is stuck in longitudinal slot 211) in the coupling end of leading sample section 20, rotate and hold sample section 10 (or leading sample section 20), clamping projection 12 is stuck in the second translot 213, and realizes appearance sample section 10 to be connected with the coupling end of leading sample section 20; Being poured into by injection port 11 by sample (i.e. cell suspension) holds in sample section 10, the sample mouth 24 of leading of leading below sample section 20 is communicated with vacuum unit and vacuumizes, after filtering sample, reverse rotation is held sample section 10 (or leading sample section 20) and is taken off appearance sample section 10; Hold the outer disk body 31 of filter member 30, and by cross structure 33, inner tray 32 is taken out.
The present embodiment tool has the following advantages:
1, because this filter member 30 has inner tray 32, outer disk body 31 and cross structure 33, when putting into or take out filtering membrane 34, outer disk body 31 can be held and operate, putting into or take out more convenient; And realize inner tray 32 (and filtering membrane 34) to put into or take out by the outer disk body 31 of operation, avoid direct contacted filter membrane 34 or sample is polluted.
2, the bottom of described longitudinal slot 211 has the first translot 212 of circumference, after cross structure 33 is placed in longitudinal slot 211, can rotate outer disk body 31 again makes cross structure 33 be stuck in the first translot 212, avoids filter member 30 arbitrarily deviate from and pollute, and improves operability and reliability further.
3, the middle part of described longitudinal slot 211 has the second translot 213 of circumferential direction, clamping projection 12 is stuck in longitudinal slot 211 and rotates the connection that can realize leading sample section 20 and holding sample section 10 along the second translot 213, clamping projection 12 can be realized leading sample section 20 and holding disassembling of sample section 10 along the second translot 213 reverse rotation, easy to use.
4, described first translot 212, second translot 213 is identical relative to the direction of described longitudinal slot 211, and when clamping protruding 12 screws in, the cross structure 33 of filter member 30 can be taken advantage of a situation and be snapped in the first translot 212, uses more convenient.
The coupling end of leading sample section 20 5, has clamping outer wall 21 and interior land 22, longitudinal slot 211 on clamping outer wall 21 can coordinate with clamping protruding 12 and realize holding sample section 10 and the connection leading sample section 20, inner tray 32 compresses by the end face holding the coupling end of sample section 10 together with interior land 22, avoids sample leakage.
The coupling end of leading sample section 20 6, also has outward flange 23, and this outward flange 23 can provide support for outer disk body 31 or protect.
7, be provided with on described outward flange 23 and step down scarce 231, by this step down scarce 231 can easily externally disk body 31 grip.
The above embodiment only have expressed the specific embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.
Claims (7)
1. filtration unit, it is characterized in that, comprise and hold sample section, lead sample section and filter member, the coupling end of leading sample section is provided with at least two longitudinal slots, and described filter member has inner tray, outer disk body, filtering membrane and at least two cross structures, and inner tray to be positioned in the middle part of outer disk body and to be connected by cross structure, inner tray is provided with filter pore, filter pore place is located at by filtering membrane, and cross structure is positioned at longitudinal slot, holds sample section and the coupling end of leading sample section and is connected by coupling device and communicated by filtering membrane;
The bottom of described longitudinal slot has the first translot of at least two circumferential direction,
The middle part of described longitudinal slot has the second translot of at least two circumferential direction, at the coupling end of described appearance sample section, there are at least two clamping projections, the quantity of clamping projection is identical with the quantity of the second translot and position relative, and described coupling device is that this second translot and clamping are protruding.
2. filtration unit according to claim 1, it is characterized in that, described first translot, the second translot are identical relative to the direction of described longitudinal slot.
3. filtration unit according to any one of claim 1 to 2, is characterized in that, described in lead sample section coupling end there is clamping outer wall and interior land, interior land is positioned at clamping outer wall, and the end face holding the coupling end of sample section is relative with interior land and inner tray compressed.
4. filtration unit according to claim 3, is characterized in that, described in lead sample section coupling end also there is outward flange, the diameter of outward flange is greater than the diameter of clamping outer wall, and described outer disk body is positioned at the top of described outward flange.
5. filtration unit according to claim 4, is characterized in that, described outward flange is provided with two and steps down scarce, two opposition sides lacking and lay respectively at outward flange of stepping down.
6. filtration unit according to claim 3, is characterized in that, the end face of coupling end holding sample section and interior land are equipped with wear ring, two wear rings respectively from both sides by two side compressions of inner tray.
7. carry out the method for filtering with the filtration unit described in any one of claim 1-6, it is characterized in that, comprise the steps:
Hold the outer disk body of filter member, by cross structure inner tray is placed in the coupling end of leading sample section, appearance sample section is connected with the coupling end of leading sample section; Take off after sample is filtered and hold sample section; Hold the outer disk body of filter member, and by cross structure, inner tray is taken out;
When inner tray is placed in the coupling end of leading sample section, cross structure is positioned at longitudinal slot, rotates outer disk body and makes cross structure be stuck in the first translot; The clamping projection holding sample section is stuck in longitudinal slot and rotates along the second translot, realizes the connection of the coupling end holding sample section and lead sample section.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310421896.6A CN103468568B (en) | 2013-09-16 | 2013-09-16 | Filtration unit, filter member and filter method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310421896.6A CN103468568B (en) | 2013-09-16 | 2013-09-16 | Filtration unit, filter member and filter method |
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| Publication Number | Publication Date |
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| CN103468568A CN103468568A (en) | 2013-12-25 |
| CN103468568B true CN103468568B (en) | 2016-03-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310421896.6A Active CN103468568B (en) | 2013-09-16 | 2013-09-16 | Filtration unit, filter member and filter method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104017722B (en) * | 2014-06-20 | 2016-03-23 | 益善生物技术股份有限公司 | Hatch strainer and hatch the incubating device of strainer containing this |
| JP6619271B2 (en) * | 2015-03-23 | 2019-12-11 | アークレイ株式会社 | Method for isolating or detecting rare cells |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN87209860U (en) * | 1987-07-08 | 1988-05-25 | 中国人民解放军总医院 | Single cell separator |
| FR2952069B1 (en) * | 2009-11-04 | 2013-06-28 | Metagenex | DEVICE AND METHOD FOR ISOLATING AND / OR CULTIVATING LIVING CELLS ON FILTER OR EXTRACTING GENETIC MATERIAL |
| US20120129252A1 (en) * | 2010-11-11 | 2012-05-24 | Seubert Ronald C | Method and system for cell filtration |
| CN202415566U (en) * | 2012-01-10 | 2012-09-05 | 王秋艳 | Filtering device for microcapsules and microcarriers |
| CN203462051U (en) * | 2013-09-16 | 2014-03-05 | 益善生物技术股份有限公司 | Filtering device and filtering element |
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| CN103468568A (en) | 2013-12-25 |
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Application publication date: 20131225 Assignee: Shanghai Yishan Medical Laboratory Co., Ltd. Assignor: Surexam Biological Technology Co., Ltd. Contract record no.: 2019990000156 Denomination of invention: Filtering device, filtering piece and filtering method Granted publication date: 20160323 License type: Common License Record date: 20190515 |