CN103468568A - Filtering device, filtering piece and filtering method - Google Patents

Filtering device, filtering piece and filtering method Download PDF

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Publication number
CN103468568A
CN103468568A CN2013104218966A CN201310421896A CN103468568A CN 103468568 A CN103468568 A CN 103468568A CN 2013104218966 A CN2013104218966 A CN 2013104218966A CN 201310421896 A CN201310421896 A CN 201310421896A CN 103468568 A CN103468568 A CN 103468568A
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China
Prior art keywords
sample section
inner tray
translot
filtering
disk body
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CN2013104218966A
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Chinese (zh)
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CN103468568B (en
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许嘉森
刘志明
吴诗扬
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Surexam Bio Tech Co Ltd
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Surexam Bio Tech Co Ltd
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Abstract

The invention discloses a filtering device, a filtering piece and a filtering method. The filtering device comprises a sample containing section, a sample guiding section and the filtering piece, wherein at least two longitudinal grooves are formed in the sample guiding section in a connecting manner; the filtering piece is internally provided with an inner disc body, an outer disc body, a filtering membrane and at least two connecting bridges; the inner disc body is arranged in the middle of the outer disc body and is connected with the middle of the outer disc body by the connecting bridges; the inner disc body is provided with a filtering hole; the filtering membrane is arranged at the filtering hole; the connecting bridges are arranged in the longitudinal grooves; the connecting ends of the sample containing section and the sample guiding section are connected by a connecting device and are communicated with the filtering membrane. The filtering device, the filtering piece and the filtering method disclosed by the invention have the advantages that the filtering membrane can be conveniently taken out and the pollution to a sample is effectively reduced.

Description

Filtration unit, filter member and filter method
Technical field
The invention belongs to medical instruments field, be specifically related to filtration unit, filter member and filter method.
Background technology
Some specific blood cells, tumour cell for example, the ratio existed is very little, yet with other cell existed in blood, compare, their volume is larger, therefore, when utilizing some instrument to detect, in order to guarantee the accuracy detected, need to be filtered cell to be detected, general cell filtration method is that blood sample is filtered by filtration unit.
In clinical medicine, also may be filtered other samples, to be detected.
But the filtration unit sold on the market now mostly is simple strainer, and its shortcoming is: the single filtration volume is little, it is extremely inconvenient to use, lose time and manpower; A kind of cell filtering device occurs again afterwards, and just still existed filtering membrane to take out inconvenient defect, even can contaminated sample in some situation.
Summary of the invention
Based on this, the invention reside in the defect that overcomes prior art, a kind of filtration unit, filter member and filter method are provided, the present invention can take out filtering membrane easily, has effectively reduced the pollution to sample.
Its technical scheme is as follows:
Filtration unit, comprise appearance sample section, lead sample section and filter member, be provided with at least two longitudinal slots in the connection of leading the sample section, described filter member has inner tray, outer disk body, filtering membrane and at least two cross structures, inner tray is positioned at outer disk body middle part and connects by cross structure, and inner tray is provided with filter pore, and filtering membrane is located at the filter pore place, cross structure is positioned at longitudinal slot, holds the sample section and is connected by coupling device and communicates by filtering membrane with the coupling end of leading the sample section.
Below further technical scheme is described:
The bottom of described longitudinal slot has the first translot of at least two circumferential direction.
The middle part of described longitudinal slot has the second translot of at least two circumferential direction, coupling end in described appearance sample section has at least two clamping projections, the quantity of the quantity of clamping projection and the second translot is identical and position is relative, and described coupling device is this second translot and clamping projection.
Described the first translot, the second translot are identical with respect to the direction of described longitudinal slot.
Described coupling end of leading the sample section has clamping outer wall and interior ring platform, and interior ring platform is positioned at the clamping outer wall, holds the end face of coupling end of sample section relative with interior ring platform and inner tray is compressed.
Described coupling end of leading the sample section also has outward flange, and the diameter of outward flange is greater than the diameter of clamping outer wall, and described outer disk body is positioned at the top of described outward flange.
Be provided with two and step down scarcely on described outward flange, step down for two and lack the opposition sides lay respectively at outward flange.
Be equipped with wear ring on the end face of the coupling end that holds the sample section and interior ring platform, two wear rings respectively from both sides by two side compressions of inner tray.
The invention also discloses a kind of filter member, have inner tray, outer disk body, filtering membrane and at least two cross structures, inner tray is positioned at outer disk body middle part and connects by cross structure, and inner tray is provided with filter pore, and filtering membrane is located at the filter pore place.
The invention also discloses a kind of filter method, it comprises the steps:
Hold the outer disk body of filter member, by cross structure, inner tray is placed in the coupling end of leading the sample section, be connected with the linkage section of leading the sample section holding the sample section; Take off after sample is filtered and hold the sample section; Hold the outer disk body of filter member, and by cross structure, inner tray is taken out.
Below the principle of aforementioned techniques scheme, effect etc. are described:
1, because this filter member has inner tray, outer disk body and cross structure, when putting into or take out filtering membrane, can hold outer disk body and be operated, put into or take out more convenient; And realize inner tray (and filtering membrane) is put into or taken out by the outer disk body of operation, avoid direct contacted filter membrane or sample is polluted.
2, the bottom of described longitudinal slot has the first circumferential translot, after cross structure is placed in longitudinal slot, can rotates outer disk body again cross structure is stuck in the first translot, avoids filter member arbitrarily deviate from and pollute, and further improves operability and reliability.
3, the middle part of described longitudinal slot has the second translot of circumferential direction, the connection that the clamping projection is stuck in to longitudinal slot and can realizes leading the sample section and hold the sample section along the second translot rotation, the clamping projection can be realized leading the sample section and holds disassembling of sample section along the second translot reverse rotation, easy to use.
4, described the first translot, the second translot are identical with respect to the direction of described longitudinal slot, and when the clamping projection screws in, the cross structure of filter member can be taken advantage of a situation and be snapped in the first translot, uses more convenient.
5, described coupling end of leading the sample section has clamping outer wall and interior ring platform, longitudinal slot on the clamping outer wall can coordinate with the clamping projection and realize holding the sample section and leading being connected of sample section, the end face that holds the coupling end of sample section compresses inner tray together with interior ring platform, avoids sample leakage.
6, described coupling end of leading the sample section also has outward flange, and this outward flange can provide support or protect for the outer disk body.
7, on described outward flange, be provided with step down scarce, by this step down lack can be easily externally disk body gripped.
The accompanying drawing explanation
Fig. 1 is the structure iron of the described filtration unit of the embodiment of the present invention;
Fig. 2 is the disassembly diagram of Fig. 1;
Fig. 3 is the structure iron of filter member;
Fig. 4 is the oblique drawing of leading the sample section;
Fig. 5 is the side-view of leading the sample section;
Fig. 6 is the use schematic flow sheet of the described filtration unit of the embodiment of the present invention;
Description of reference numerals:
10, hold the sample section, 11, injection port, 12, the clamping projection, 20, lead the sample section, 21, the clamping outer wall, 211, longitudinal slot, 212, the first translot, the 213, second translot, 22, interior ring platform, 23, outward flange, 231, step down scarce, 24, lead the sample mouth, 30, filter member, 31, outer disk body, 32, inner tray, 33, cross structure, 34, filtering membrane, 40, wear ring.
Embodiment
Below embodiments of the invention are elaborated:
As shown in Figures 1 to 5, filtration unit, comprise appearance sample section 10, lead sample section 20 and filter member 30, be provided with at least two longitudinal slots 211 in the connection of leading sample section 20, described filter member 30 has inner tray 32, outer disk body 31, filtering membrane 34 and two cross structures 33, inner tray 32 is positioned at outer disk body 31 middle parts and connects by cross structure 33, inner tray 32 is provided with filter pore, filtering membrane 34 is located at the filter pore place, cross structure 33 is positioned at longitudinal slot 211, holds sample section 10 and is connected by coupling device and communicates by filtering membrane 34 with the coupling end of leading sample section 20.
Wherein, the bottom of described longitudinal slot 211 has the first translot 212 of two circumferential direction, the middle part of described longitudinal slot 211 has the second translot 213 of two circumferential direction, described the first translot 212, the second translot 213 are identical with respect to the direction of described longitudinal slot 211, coupling end in described appearance sample section 10 has two clamping projections 12, the quantity of the quantity of clamping projection 12 and the second translot 213 is identical and position is relative, and described coupling device is this second translot 213 and clamping projection 12.
Described coupling end of leading sample section 20 has clamping outer wall 21 and interior ring platform 22, interior ring platform 22 is positioned at clamping outer wall 21, hold the end face of coupling end of sample section 10 relative with interior ring platform 22 and by inner tray 32 compressions, for the enhanced leaktightness effect, on the end face of the coupling end that holds sample section 10 and interior ring platform 22, be equipped with 40, two wear rings 40 of wear ring respectively from both sides by two side compressions of inner tray 32.Described coupling end of leading sample section 20 also has outward flange 23, and the diameter of outward flange 23 is greater than the diameter of clamping outer wall 21, and described outer disk body 31 is positioned at the top of described outward flange 23.Being provided with two on described outward flange 23 steps down and lacks 231, two and step down and lack 231 opposition sides that lay respectively at outward flange 23.
The use flow process of this filtration unit as shown in Figure 6, hold the outer disk body 31 of filter member 30, by cross structure 33, inner tray 32 is placed in (now cross structure 33 is stuck in longitudinal slot 211) in the coupling end of leading sample section 20, sample section 10 (or leading sample section 20) are held in rotation, clamping projection 12 is stuck in the second translot 213, and realizes that will hold sample section 10 is connected with the linkage section of leading sample section 20; Sample (being cell suspension) is poured into and held in sample section 10 by injection port 11, the sample mouth 24 of leading of leading sample section 20 belows is communicated with vacuum unit and vacuumizes, after sample is filtered, reverse rotation is held sample section 10 (or leading sample section 20) and is taken off and hold sample section 10; Hold the outer disk body 31 of filter member 30, and by cross structure 33, inner tray 32 is taken out.
The present embodiment has following advantage:
1, because this filter member 30 has inner tray 32, outer disk body 31 and cross structure 33, when putting into or take out filtering membrane 34, can hold outer disk body 31 and be operated, put into or take out more convenient; And realize inner tray 32 (and filtering membrane 34) is put into or taken out by the outer disk body 31 of operation, avoid direct contacted filter membrane 34 or sample is polluted.
2, the bottom of described longitudinal slot 211 has the first circumferential translot 212, after cross structure 33 is placed in longitudinal slot 211, can rotate again outer disk body 31 cross structure 33 is stuck in the first translot 212, avoid filter member 30 arbitrarily deviate from and pollute, further improve operability and reliability.
3, the middle part of described longitudinal slot 211 has the second translot 213 of circumferential direction, the connection that clamping projection 12 is stuck in to longitudinal slot 211 and can realizes leading sample section 20 and hold sample section 10 along the second translot 213 rotations, clamping projection 12 can be realized leading sample section 20 and holds disassembling of sample section 10 along the second translot 213 reverse rotations, easy to use.
4, described the first translot 212, the second translot 213 are identical with respect to the direction of described longitudinal slot 211, and when clamping projection 12 screws in, the cross structure 33 of filter member 30 can be taken advantage of a situation and be snapped in the first translot 212, uses more convenient.
5, described coupling end of leading sample section 20 has clamping outer wall 21 and interior ring platform 22, longitudinal slot 211 on clamping outer wall 21 can coordinate with clamping projection 12 and realize holding sample section 10 and leading being connected of sample section 20, the end face that holds the coupling end of sample section 10 compresses inner tray 32 together with interior ring platform 22, avoids sample leakage.
6, described coupling end of leading sample section 20 also has outward flange 23, and this outward flange 23 can provide support or protect for outer disk body 31.
7, be provided with to step down on described outward flange 23 and lack 231, by this step down lack 231 can be easily externally disk body 31 gripped.
The above embodiment has only expressed the specific embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.

Claims (10)

1. filtration unit, it is characterized in that, comprise appearance sample section, lead sample section and filter member, be provided with at least two longitudinal slots in the connection of leading the sample section, described filter member has inner tray, outer disk body, filtering membrane and at least two cross structures, and inner tray is positioned at outer disk body middle part and connects by cross structure, inner tray is provided with filter pore, filtering membrane is located at the filter pore place, and cross structure is positioned at longitudinal slot, holds the sample section and is connected by coupling device and communicates by filtering membrane with the coupling end of leading the sample section.
2. filtration unit according to claim 1, is characterized in that, the bottom of described longitudinal slot has the first translot of at least two circumferential direction.
3. filtration unit according to claim 2, it is characterized in that, the middle part of described longitudinal slot has the second translot of at least two circumferential direction, coupling end in described appearance sample section has at least two clamping projections, the quantity of the quantity of clamping projection and the second translot is identical and position is relative, and described coupling device is this second translot and clamping projection.
4. filtration unit according to claim 3, is characterized in that, described the first translot, the second translot are identical with respect to the direction of described longitudinal slot.
5. according to the described filtration unit of any one in claim 1 to 4, it is characterized in that, described coupling end of leading the sample section has clamping outer wall and interior ring platform, and interior ring platform is positioned at the clamping outer wall, holds the end face of coupling end of sample section relative with interior ring platform and inner tray is compressed.
6. filtration unit according to claim 5, is characterized in that, described coupling end of leading the sample section also has outward flange, and the diameter of outward flange is greater than the diameter of clamping outer wall, and described outer disk body is positioned at the top of described outward flange.
7. filtration unit according to claim 6, is characterized in that, is provided with two and steps down scarcely on described outward flange, steps down for two and lack the opposition sides that lay respectively at outward flange.
8. filtration unit according to claim 5, is characterized in that, on the end face of the coupling end that holds the sample section and interior ring platform, is equipped with wear ring, two wear rings respectively from both sides by two side compressions of inner tray.
9. filter member, is characterized in that, has inner tray, outer disk body, filtering membrane and at least two cross structures, and inner tray is positioned at outer disk body middle part and connects by cross structure, and inner tray is provided with filter pore, and filtering membrane is located at the filter pore place.
10. filter method, is characterized in that, comprises the steps:
Hold the outer disk body of filter member, by cross structure, inner tray is placed in the coupling end of leading the sample section, be connected with the linkage section of leading the sample section holding the sample section; Take off after sample is filtered and hold the sample section; Hold the outer disk body of filter member, and by cross structure, inner tray is taken out.
CN201310421896.6A 2013-09-16 2013-09-16 Filtration unit, filter member and filter method Active CN103468568B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104017722A (en) * 2014-06-20 2014-09-03 益善生物技术股份有限公司 Incubation filter and incubation device comprising same
JP2016180753A (en) * 2015-03-23 2016-10-13 アークレイ株式会社 Method of isolating or detecting rare cells

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN87209860U (en) * 1987-07-08 1988-05-25 中国人民解放军总医院 Single cell separator
CN202415566U (en) * 2012-01-10 2012-09-05 王秋艳 Filtering device for microcapsules and microcarriers
CN103201374A (en) * 2009-11-04 2013-07-10 史格林细胞公司 Device and method for isolating and cultivating living cells on a filter or extracting the genetic material thereof from same
CN103298546A (en) * 2010-11-11 2013-09-11 瑞尔赛特股份有限公司 Method and system for cell filtration
CN203462051U (en) * 2013-09-16 2014-03-05 益善生物技术股份有限公司 Filtering device and filtering element

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN87209860U (en) * 1987-07-08 1988-05-25 中国人民解放军总医院 Single cell separator
CN103201374A (en) * 2009-11-04 2013-07-10 史格林细胞公司 Device and method for isolating and cultivating living cells on a filter or extracting the genetic material thereof from same
CN103298546A (en) * 2010-11-11 2013-09-11 瑞尔赛特股份有限公司 Method and system for cell filtration
CN202415566U (en) * 2012-01-10 2012-09-05 王秋艳 Filtering device for microcapsules and microcarriers
CN203462051U (en) * 2013-09-16 2014-03-05 益善生物技术股份有限公司 Filtering device and filtering element

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104017722A (en) * 2014-06-20 2014-09-03 益善生物技术股份有限公司 Incubation filter and incubation device comprising same
CN104017722B (en) * 2014-06-20 2016-03-23 益善生物技术股份有限公司 Hatch strainer and hatch the incubating device of strainer containing this
JP2016180753A (en) * 2015-03-23 2016-10-13 アークレイ株式会社 Method of isolating or detecting rare cells

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EE01 Entry into force of recordation of patent licensing contract

Application publication date: 20131225

Assignee: Shanghai Yishan Medical Laboratory Co., Ltd.

Assignor: Surexam Biological Technology Co., Ltd.

Contract record no.: 2019990000156

Denomination of invention: Filtering device, filtering piece and filtering method

Granted publication date: 20160323

License type: Common License

Record date: 20190515

EE01 Entry into force of recordation of patent licensing contract