CN103316297A - 一种治疗萎缩性鼻炎的中药 - Google Patents
一种治疗萎缩性鼻炎的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗萎缩性鼻炎的中药，它是由以下重量配比的原料药材制备而成：桉紫地榆8克、蘡薁根14克、荠苨6克、沙苑子9克、黄精4克、莪术8克、没药10克、见血飞10克、三颗针10克、九龙藤8克、血竭4克。临床实验证明，本发明能够安全有效治疗萎缩性鼻炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗萎缩性鼻炎的中药。
背景技术
萎缩性鼻炎是一种发展缓慢的鼻腔慢性炎性疾病，发病具有地区性。本病女性患者较多，多发于青壮年，健康状况及生活条件差者易患此病，近年来呈现逐渐减少的趋势。其特点是鼻黏膜干燥、萎缩，鼻腔增大，嗅觉障碍，鼻腔内有大量黄绿色脓痴形成。主要症状：鼻及鼻咽干燥感，鼻塞，鼻出血，头疼、头昏等。
本病病因西医理论尚不清楚，近年来研究发现本病患者大多有免疫功能紊乱，故提出本病可能是一种自身免疫病。故而亦缺乏公认有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
紫地榆【来源】牻牛儿苗科老鹤草属植物紫地榆，以根入药。秋季采挖，洗净切片晒干。别名隔山消、赤地榆，以根入药。【功能主治】清热利湿，活血止血。用于肠炎，痢疾，消化不良，慢性胃炎，***，鼻衄；外用治跌打损伤。
蘡薁根【来源】为葡萄科植物蘡薁的根，全年可采。【功能主治】清湿热，消肿毒。治黄疸，湿痹，热淋，痢疾，肿毒，瘰疬，跌打损伤。治下焦热痛淋闷，消肿毒。治胃痛，疗痔疮，通经利尿。
荠苨【来源】为桔梗科植物荠苨的根。我国各地山野平原都有分布。【功能主治】清热，解毒，化痰。治燥咳，喉痛，消渴，疔疮肿毒。解百药毒，利肺气，和中，明目，止痛。
沙苑子【来源】为豆科一年生草本植物扁茎黄芪的成熟种子，秋末冬初果实成熟尚未开裂时采割植株，晒干，打下种子。生用或炒用。【功能主治】补肝，益肾，明目，固精。治肝肾不足，腰膝酸痛，目昏，遗精早泄，小便频数，遗尿，尿血，白带。
黄精【来源】又名老虎姜、鸡头参。百合科植物滇黄精、黄精或多花黄精的干燥根茎。以根茎入药。【功能主治】具有补气养阴，健脾，润肺，益肾功能。用于治疗脾胃虚弱，体倦乏力，口干食少，肺虚燥咳，精血不足，内热消渴等症。
莪术【来源】莪术为多年生宿根草本。姜科植物蓬莪术、广西莪术或温郁金的干燥根茎。【功能主治】行气破血，消积止痛。用于燀瘕痞块，瘀血经闭，食积胀痛；早期***。
没药【来源】橄榄树科植物地丁树、哈地丁树，树干部渗出的油胶树脂。分为天然没药和胶质没药。【功能主治】散血去瘀，消肿定痛。治跌打损伤、金疮、筋骨、心腹诸痛、症瘕、经闭、痈疽肿痛、痔漏、目障。
见血飞【来源】于芸香科植物刺异叶花椒的根或根皮。辛，温。功效祛风散寒。【功能主治】活血舒筋，治风寒咳嗽，风湿麻木。《贵州草药》：驱风，散寒。
三颗针【来源】于小檗科植物刺黑珠、毛叶小檗、黑石珠等的根皮或茎皮。性寒，微苦。【功能主治】清热，利湿，散瘀的功效。治疗赤痢，黄疸，咽痛，目赤，跌打损伤。
九龙藤【来源】于豆科植物龙须藤的茎。苦辛，平，无毒。【功能主治】祛风、去瘀、止痛的作用。治疗风湿骨痛、跌打损伤。
血竭【来源】别名：骐驎竭、海蜡、麒麟血、木血竭。棕榈科植物麒麟竭果实和藤茎中的树脂。【功能主治】内服活血散瘀，定痛，外用止血生肌，敛疮。主治：①淤血经闭、痛经，产后瘀阻。②症瘕痞块，胸腹刺痛。③跌打损伤，淤血肿痛。④外伤出血，溃疡不敛。
发明内容
本发明旨在提供一种治疗萎缩性鼻炎的中药，通过选择合适的药材及其配比，达到安全有效治愈萎缩性鼻炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗萎缩性鼻炎的中药，其特征在于，它是由以下重量配比的原料药材制备而成：紫地榆8克、蘡薁根14克、荠苨6克、沙苑子9克、黄精4克、莪术8克、没药10克、见血飞10克、三颗针10克、九龙藤8克、血竭4克。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年10月-2012年6月间共收集120例萎缩性鼻炎的门诊患者，年龄16-54岁，病程1-8年。随机分为：治疗组85例，空白组35例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程30天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程30天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(％) |
| 治疗组 | 85 | 14(16.5％) | 52(61.2％) | 19(22.3％) | 77.7％ |
| 空白组 | 35 | 0 | 5(14.3％) | 30(85.7％) | 14.3％ |
可见，本发明制得的药物能够安全有效治疗萎缩性鼻炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：紫地榆8克、蘡薁根14克、荠苨6克、沙苑子9克、黄精4克、莪术8克、没药10克、见血飞10克、三颗针10克、九龙藤8克、血竭4克；加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人一天用量的胶囊剂。
用于治疗萎缩性鼻炎。口服，每日分早晚两次服用。
具体实施例2
称取：紫地榆8克、蘡薁根14克、荠苨6克、沙苑子9克、黄精4克、莪术8克、没药10克、见血飞10克、三颗针10克、九龙藤8克、血竭4克；加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常成人一天用量的散剂。
用于治疗萎缩性鼻炎。口服，每日一次。
具体实施例3
称取：紫地榆8克、蘡薁根14克、荠苨6克、沙苑子9克、黄精4克、莪术8克、没药10克、见血飞10克、三颗针10克、九龙藤8克、血竭4克；加6倍量水，煎煮3次，每次煎煮1小时，合并煎煮液，浓缩，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人一天用量的颗粒剂。
用于治疗萎缩性鼻炎。口服，每日分早中晚三次服用。
Claims (1)
1.一种治疗萎缩性鼻炎的中药，其特征在于，它是由以下重量配比的原料药材制备而成：紫地榆8克、蘡薁根14克、荠苨6克、沙苑子9克、黄精4克、莪术8克、没药10克、见血飞10克、三颗针10克、九龙藤8克、血竭4克。
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| CN1857597A (zh) * | 2005-04-30 | 2006-11-08 | 谢建平 | 一种治疗鼻炎的中药 |
| CN101537089A (zh) * | 2008-03-21 | 2009-09-23 | 北京中泰天和科技有限公司 | 一种治疗过敏性鼻炎的药物组合及其制备方法 |
| CN101612300A (zh) * | 2008-06-27 | 2009-12-30 | 韩庆亮 | 一种治疗萎缩性鼻炎的中药药剂 |
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| CN1857597A (zh) * | 2005-04-30 | 2006-11-08 | 谢建平 | 一种治疗鼻炎的中药 |
| CN101537089A (zh) * | 2008-03-21 | 2009-09-23 | 北京中泰天和科技有限公司 | 一种治疗过敏性鼻炎的药物组合及其制备方法 |
| CN101612300A (zh) * | 2008-06-27 | 2009-12-30 | 韩庆亮 | 一种治疗萎缩性鼻炎的中药药剂 |
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| 徐静: "鼻炎选方用药临床经验介绍", 《中华中医药学会耳鼻喉科分会第15届学术交流会论文集》, 31 December 2009 (2009-12-31) * |
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| CN104173546A (zh) * | 2014-09-03 | 2014-12-03 | 王继礼 | 治疗鼻炎的中药水 |
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