CN103272085A - Traditional Chinese medicine composition for treating eperythrozoonosis of dairy cows and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating eperythrozoonosis of dairy cows and a preparation method thereof, and relates to a medicine for treating eperythrozoonosis of dairy cows. The traditional Chinese medicine composition is formed by mixing antifebrile dichroa, areca-nut, isatis root, fructus forsythiae, radix scrophulariae, Codonopsis pilosula, Angelica sinensis, Rhizoma Atractylodis Macrocephalae, liquorice and Artemisia apiacea. The preparation method comprises the following steps of: mixing the raw materials; adding water to soak and decoct for a certain time; and filtering. The composition is safe, effective and free from resistance to medicine, and has the functions of killing worms and removing qi stagnation, clearing away heat and toxic materials, stopping bleeding and cooling blood, tonifying qi and blood, harmonizing stomach and tonifying spleen, and enhancing the resistance and immunity of a human body.

Description

A kind of Chinese medicine composition for the treatment of the milch cow eperythrozoonosis and preparation method thereof

Technical field

The invention belongs to the herbal medicine compositions, particularly be a kind of milch cow eperythrozoonosis composition and method of making the same for the treatment of.

Background technology

The milch cow eperythrozoonosis is to parasitize ORBC surface, blood plasma and bone marrow by Eperythrozoon, is a kind of zoonosis of Clinical symptoms with anemia, hemolytic jaundice, heating, dyspnea.China is one of popular the most serious country of milch cow eperythrozoonosis, and existing 20 provinces, cities and autonomous regions report the generation of this disease at present.Along with developing rapidly of milk cattle cultivating industry, intensive degree is more and more higher, and this disease changes four seasons morbidity into by the seasonality morbidity, and indivedual regional milch cow Eperythrozoon infection rates are up to 50%-90%.This disease can cause that milch cow grows slowly, milk yield descends and breeding difficulty, and normal concurrent with productivity diseases such as endometritis, mastitis and parturient paresises, already brings enormous economic loss to milk cattle cultivating.Simultaneously, the milch cow eperythrozoonosis human beings'health as a kind of zoonosis serious threat, and some regional people's infection rate is up to 40%, in the teenager even can reach more than 70%, show as chronic fatigue syndrome, the unusual and sleep disorder of function of nervous system also appears in part patient.Because most of patients infects back performance sub-health state, this disease is cured clinical often out in the cold the people.

The specific drug for the treatment of milch cow eperythrozoonosis seldom mainly adopt antiparasitic Western medicine imidazophenylurea, Diminazene Aceturate (Benny's that) and oxytetracycline, doxycycline, penicillin to wait the deinsectization anti-inflammation clinically, but effect is all undesirable at present.It is more effective that imidazophenylurea is treated this disease, but this medicine can not enter bone marrow, can not thoroughly kill Eperythrozoon, and expensive, and drug withdrawal is easily recurred.Diminazene Aceturate has bigger toxic and side effects, and safety range is little, easily produces drug residue.

Summary of the invention

Using antibiotics, to treat this disease effect imprecise, and polypide easily produces drug resistance, and can not thoroughly remove pathogen, easily causes drug residue.Arsenic preparation metrifonate liquid can be treated the cattle eperythrozoonosis, but easily causes the residual of poisonous arsenic in beef and the milk.

The Chinese medicine prescription of malaria commonly used and anthelmintic is treated this disease clinically, as the prescription of people such as Guo Hongjun research and development: Herba Artemisiae Annuae, Radix Dichroae, Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Semen Lepidii (Semen Descurainiae), Cortex Lycii, Cortex Mori, the Rhizoma Anemarrhenae, Radix Scutellariae, Radix Glycyrrhizae; And for example ten thousand states are along the prescription that waits the people: Herba Artemisiae Annuae, Cornu Bubali, Radix Scrophulariae, Fructus Gardeniae, Radix Platycodonis, Radix Scutellariae, the Rhizoma Anemarrhenae, the Radix Paeoniae Alba, Fructus Forsythiae, the Radix Rehmanniae, bright Folium Bambusae, Cortex Moutan, Radix Arnebiae (Radix Lithospermi), Herba Ecliptae, Herba Agrimoniae, Herba Ecliptae, Radix Glycyrrhizae.This class prescription comprise have the Radix Scrophulariae that rushes down following function, Gypsum Fibrosum etc., when driving away polypide, can rush down interior-heat down, certain curative effect is arranged, but fails to alleviate anemia and jaundice symptom, insufficiency of the spleen loose stool can appear in the more weak sick cattle of body constitution, increases the weight of the state of an illness.See also that clinically therapy of combining Chinese and Western medicine should disease, the Chinese medicine prescription of common collocation Western medicine has decoction of ten powerful tonics, Radix Codonopsis to support flourish soup etc.The SHIQUAN DABU FANG combined with westem can obviously be alleviated anemia, jaundice and the anaphylaxis that causes because of the infection Eperythrozoon, but can not thoroughly remove polypide, easily repeatedly.Radix Codonopsis is supported flourish soup energy mitigate the disease, improves and suffers from poultry appetite, but can not remove polypide, easily recurs, and cures the symptoms, not the disease.So developing the Chinese medicine composition of safe and efficient treatment milch cow eperythrozoonosis already develops in a healthy way significant to milk cattle cultivating.

Summary of the invention

The objective of the invention is the problem at present treatment milch cow eperythrozoonosis existence, research and develop a kind of Chinese medicine composition for the treatment of the milch cow eperythrozoonosis and preparation method thereof, reach and improve milch cow eperythrozoonosis cure rate, be difficult for recurrence, and purpose with low cost, that have no side effect.

The object of the present invention is achieved like this: said composition is prepared by following raw material and consumption: Radix Dichroae 45-60g, Semen Arecae 45-60g, Radix Isatidis 45-60g, Fructus Forsythiae 30-50g, Radix Scrophulariae 20-40g, Radix Codonopsis 40-60g, Radix Angelicae Sinensis 40-60g, Rhizoma Atractylodis Macrocephalae 40-60g, Radix Glycyrrhizae 30-50g, Herba Artemisiae Annuae 20-45g.Add normal-temperature water 2000-2500ml in whole Radix Dichroae, Semen Arecae, Radix Isatidis, Fructus Forsythiae, Radix Scrophulariae, Radix Codonopsis, Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, the Radix Glycyrrhizae in the dosage, soaked 60 minutes, 30-45 at a simmer minute, filter and remove residue got the about 50mL of medicinal liquid; Add 1500-2000mL water in the medicinal residues after filter again, 30-45 at a simmer minute, filter the about 50mL of medicinal liquid, the medicinal liquid that merges twice filtration gained, after the medicinal liquid that merges is down to 50-60 ℃, the Herba Artemisiae Annuae that insulation immersion 20-45g batters down 2 hours is crossed the elimination medicinal residues, finally obtains the Chinese medicine composition of potion treatment milch cow eperythrozoonosis.

This Chinese medicine composition extensive, with low cost, safe and effective, no Drug resistance, easy to use, not repeatedly of drawing materials has that killing insect and eliminating accumulation, heat-clearing and toxic substances removing, hemostasis removing heat from blood, QI invigorating are enriched blood, an effect of stomach function regulating spleen invigorating, enhancing body resistance and immunity.In several years, adopt said composition that 153 milch cows that suffer from the milch cow eperythrozoonosises are treated, cures 140, dead 3, cure rate reaches more than 90%, and after the healing not repeatedly, evident in efficacy.This Chinese medicine composition is significant for the sound development for the treatment of milch cow eperythrozoonosis, promotion milk cattle cultivating industry.

The specific embodiment

Give an actual example below and describe the present invention.

Get Radix Dichroae 50g, Semen Arecae 50g, Radix Isatidis 45g, Fructus Forsythiae 30g, Radix Scrophulariae 30g, Radix Codonopsis 45g, Radix Angelicae Sinensis 45g, Rhizoma Atractylodis Macrocephalae 45g, Radix Glycyrrhizae 35g, Herba Artemisiae Annuae 30g respectively.

Process for preparation is as follows: add normal-temperature water 2000mL in whole Radix Dichroae, Semen Arecae, Radix Isatidis, Fructus Forsythiae, Radix Scrophulariae, Radix Codonopsis, Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, the Radix Glycyrrhizae in the dosage, soaked 60 minutes, 40 minutes at a simmer, filter and remove residue got the about 50mL of medicinal liquid; Add 2000mL water in the medicinal residues after filter again, 40 minutes at a simmer, filter the about 50mL of medicinal liquid, merge twice medicinal liquid, after the medicinal liquid that merges is down to 50-60 ℃, the Herba Artemisiae Annuae that insulation immersion 45g batters down 2 hours is crossed the elimination medicinal residues, obtains the Chinese medicine composition of potion treatment milch cow eperythrozoonosis.

Using method is as follows: gavage to ill milch cow the compositions of the above-mentioned treatment milch cow eperythrozoonosis Chinese medicine that is mixed with, each once 1 dose of every day, is drunk the state of an illness and is used in conjunction the 4-7 agent sooner or later.

Treat disease row 1

4 years old breast milk cattle of cowboying family, Shangzhi City, Heilongjiang Province on the 6th August in 2012 man is ill; main suit: this milch cow ill fever before one week; veterinary station is diagnosed as eperythrozoonosis in the township; be down to normally through Western medicine imidazophenylurea treatment body temperature, but lacking of eating ruminated few; out of spirits; Sleep hyperhidrosis was once used treatments such as cephalosporin, dense glucose, aminoacid, caffeine and sodium benzoate, DeGrain.Examine it, the trouble carcass is tired unable, is reluctant to walk, and the eye conjunctiva is yellowish, diarrhea, and yellowish urine, palpitation and being susceptible to fright is diagnosed as the Eperythrozoon positive through this city animal epidemic monitoring center.Use above-mentioned traditional Chinese medicine composition for treating, serve on 6 doses 1 dose of every day, main state medication sx after the 3rd day, recovery from illness in the 6th day.Phone is paid a return visit after half a year, not recurrence again.

Treat disease row 2

On May 28th, 2012, a revive cow head of certain raising of Liuhe town, Mulan County, Heilongjiang Province, body weight 600 kg, daily output fresh milk 30 kg, 90 days puerperal, unexpected poor appetite was slow in action, and spirit is depressed, and milk yield descends, and cough is suffered from diarrhoea.Clinical examination: it is thin to suffer from cattle, visual mucosa and breast xanthochromia, rumen peristalsis weakens, and by the urgent consultation of doctors and lab testing, determines the Eperythrozoon positive, adopt Benny you to suffering from the commentaries on classics of getting better slightly after the Niu Jinhang treatment, but the state of an illness is again repeatedly after stopping to treat first quarter moon.Sick cattle is used above-mentioned traditional Chinese medicine composition for treating immediately, serve on 5 doses 1 dose of every day, main state medication after second day symptom namely alleviate, suffer from cattle and recover the diet desire gradually, recovered further consultation behind the first quarter moon on the 5th day, it is normal to suffer from drink heavily appetite, and milk yield increases, and have sharp ears blood smear microscopy Eperythrozoon is turned out cloudy.

Treat disease row 3

Have 9 adult cattle appetite to descend in mid-July, 2012 in 23 cow heads of Baicheng City cattle farm, Jilin Province, ruminate minimizing, and fervescence breathes fast to 40-41.5 ℃, and milk yield descends; Hematuria appears in the minority cattle, and constipation alternately occurs with diarrhoea, and 3 sick beefsteak hemafecias are arranged, wherein 1 conceived cow miscarriage; There are 2 calves jaundice to occur.According to clinical symptoms and blood smear microscopy result, it is eperythrozoonosis that cattle is suffered from diagnosis, and you treat in conjunction with oxytetracycline to take Benny, do not become effective.Use above-mentioned traditional Chinese medicine composition for treating immediately, serve on 7 doses 1 dose of every day, the 3rd day symptom obviously alleviated after the master stated most sick cattle medications, recovered normal after the 7th day.A seriously ill adult milch cow skeletonize is arranged, in death in second day for the treatment of.After death cut open inspection and find, the cattle corpse skeletonize of dying of illness, skin elasticity reduces, and cadaveric rigidity is obvious; Pale, the xanthochromia of visual mucosa; Lymph nodes of body as a whole enlargement, cortex are aubergine or taupe, the tangent plane succulence that turns up; Blood coagulation is bad, is cerise; The cardiac muscle expansion, pale soft, visceral pericardium, the heart are preced with fatty xanthochromia and are dispersed in the remote hemorrhage point that differs in size; The liver enlargement is pale brown color; The gallbladder enlargement, bile is dense thick; The kidney edema has a small amount of petechia; Other is organized and is not seen obvious pathological changes to cut open inspection.Treat 9 routine sick milch cows for this plant altogether, cure 8 examples, dead 1 example.

Treat disease row 4

In November, 2012, the author has accepted 1 milch cow that suffers from eperythrozoonosis for medical treatment.39.8 ℃ of sick cattle body temperature, the quilt hair is thick random, and spirit is depressed, and appetite reduces or useless cutting off with ruminating; Visual mucosa xanthochromia is with mastitis; Constipation, the stiff mucus that is covered with of feces.Through this Chinese medicine composition material treatment, sick cattle was clearly better after 3 days, recovered normal after 7 days, after one week of drug withdrawal, detected through blood smear acridine orange dyeing microscopic examination and elisa respectively, and the result transfers feminine gender to.

Claims (2)

1. Chinese medicine composition for the treatment of the milch cow eperythrozoonosis is characterized in that said composition is by following raw material and consumption preparation: Radix Dichroae 45-60g, Semen Arecae 45-60g, Radix Isatidis 45-60g, Fructus Forsythiae 30-50g, Radix Scrophulariae 20-40g, Radix Codonopsis 40-60g, Radix Angelicae Sinensis 40-60g, Rhizoma Atractylodis Macrocephalae 40-60g, Radix Glycyrrhizae 30-50g, Herba Artemisiae Annuae 25-45g.

2. the Chinese medicine composition preparation method of a treatment as claimed in claim 1 milch cow eperythrozoonosis, it is characterized in that and to add normal-temperature water 2000-2500mL in Radix Dichroaes whole in the dosage, Semen Arecae, Radix Isatidis, Fructus Forsythiae, Radix Scrophulariae, Radix Codonopsis, Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, the Radix Glycyrrhizae, soaked 45 minutes, 30-45 at a simmer minute, filter and remove residue got the about 50mL of medicinal liquid; Add 1500-2000mL water in the medicinal residues after filter again, 30-45 at a simmer minute, filter the about 50mL of medicinal liquid, merge twice medicinal liquid, after the medicinal liquid that merges is cooled to 50-60 ℃, the Herba Artemisiae Annuae that insulation immersion 25-45g batters down 2 hours, filter and remove residue finally obtains the Chinese medicine composition that potion is treated the milch cow eperythrozoonosis.